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19 results on '"Wall, Dominic"'

5. Abstract LB-023: Dynamic real time in vivo CAR T cell tracking: Clinical and preclinical studies using a novel dual PET-MR imaging agent

Author

Singla, Ritu, primary, Wall, Dominic, additional, Anderson, Samuel, additional, Zia, Nicholas, additional, Korte, James C., additional, Kravets, Lucy, additional, McKiernan, Gerard, additional, Butler, Jeanne, additional, Gammilonghi, Amanda, additional, Arora, Jyoti, additional, Solomon, Ben, additional, Hicks, Rodney, additional, Cain, Timothy, additional, Darcy, Phillip, additional, Cullinane, Carleen, additional, Neeson, Paul, additional, Ramanathan, Rajesh, additional, Shukla, Ravi, additional, Bansal, Vipul, additional, and Harrison, Simon, additional

Published
2020
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6. Positioning a Scientific Community on Unproven Cellular Therapies: The 2015 International Society for Cellular Therapy Perspective

Author

Dominici, Massimo, primary, Nichols, Karen, additional, Srivastava, Alok, additional, Weiss, Daniel J., additional, Eldridge, Paul, additional, Cuende, Natividad, additional, Deans, Robert J., additional, Rasko, John E.J., additional, Levine, Aaron D., additional, Turner, Leigh, additional, Griffin, Deborah L., additional, O'Donnell, Lynn, additional, Forte, Miguel, additional, Mason, Chris, additional, Wagena, Edwin, additional, Janssen, William, additional, Nordon, Robert, additional, Wall, Dominic, additional, Ho, Hong-Nerng, additional, Ruiz, Milton A., additional, Wilton, Steve, additional, Horwitz, Edwin M., additional, and Gunter, Kurt C., additional

Published
2015
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7. Persistence and Efficacy of Second Generation CAR T Cell Against the LeY Antigen in Acute Myeloid Leukemia

Author

Ritchie, David S., primary, Neeson, Paul J., additional, Khot, Amit, additional, Peinert, Stefan, additional, Tai, Tsin, additional, Tainton, Kellie, additional, Chen, Karen, additional, Shin, Mandy, additional, Wall, Dominic M., additional, Hönemann, Dirk, additional, Gambell, Peter, additional, Westerman, David A., additional, Haurat, Javier, additional, Westwood, Jennifer A., additional, Scott, Andrew M., additional, Kravets, Lucy, additional, Dickinson, Michael, additional, Trapani, Joseph A., additional, Smyth, Mark J., additional, Darcy, Phillip K., additional, Kershaw, Michael H., additional, and Prince, H. Miles, additional

Published
2013
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8. Low Dose Lenalidomide and Dexamethasone Induction Followed by Autologous Transplantation In Untreated Patients with Myeloma Is Associated with High Response Rates and Preservation of CD8, but Not CD4 or NK Cellular Immunity

Author

Harrison, Simon J., primary, Khot, Amit S, additional, Tsin, Tsin, additional, Hsu, Andy, additional, Chen, Karen, additional, Loudovaris, Maureen, additional, Neeson, Paul, additional, Wall, Dominic, additional, Sedunary, Rebecca, additional, Prince, H. Miles, additional, and Ritchie, David, additional

Published
2011
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9. Autologous Peripheral Blood T Lymphocytes Transduced with An Anti LewisY Chimeric Receptor Gene Persist In Patients with Lewisy Positive Acute Myeloid Leukaemia and Show Changes In Functional Polarization After Adoptive Transfer,

Author

Neeson, Paul, primary, Khot, Amit S, additional, Peinert, Stefan, additional, Tai, Tsin Y, additional, Chen, Karen, additional, Tainton, Kellie, additional, Wall, Dominic, additional, Hoenemann, Dirk, additional, Kershaw, Michael H, additional, Westwood, Jennifer, additional, Trapani, Joe, additional, Smyth, Mark J, additional, Darcy, Phillip, additional, Scott, Andrew, additional, Kravets, Lucy, additional, Davison, Jill, additional, Dickinson, Michael J., additional, Ritchie, David, additional, and Prince, Miles, additional

Published
2011
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10. Characterisation of the anticoagulant properties of a range of structurally diverse sulfated oligosaccharides

Author

Wall, Dominic, Douglas, S, Ferro, Vito, Cowden, William, Parish, Christopher, Wall, Dominic, Douglas, S, Ferro, Vito, Cowden, William, and Parish, Christopher

Abstract

In this study, 17 sulfated oligosaccharides were assessed by the activated partial thromboplastin time (APTT) test for their anticoagulant activity and nine were found to exhibit significant activity. Chain length, monosaccharide makeup, and linkage all appear to be critical factors in determining anticoagulant activity, with the most active compounds being five- to sixfold less potent than unfractionated heparin (UFH). Phosphomannopentaose sulfate (PI-88), one of the most active sulfated oligosaccharides and a promising anticancer drug, was selected for further study. PI-88 gave a more linear APTT dose-response curve and displayed less patient-to-patient variation than UFH, with its activity being neutralised by protamine sulfate. However, PI-88 showed considerable species-to-species variation in its anticoagulant effect. It was found that PI-88 acted as an anticoagulant by enhancing the ability of heparin cofactor II (HCII) to inhibit thrombin, and did not act via antithrombin III (AT-III) in either inhibiting Factor Xa or thrombin. PI-88 also mildly prolonged the prothrombin time (PT), whilst it had no platelet pro-aggregatory activity, nor did it demonstrate direct fibrinolytic activity. Thus, PI-88 represents a potential antithrombotic agent deserving further study.

Published
2001

11. Comparing a Novel PET Agent, Yttrium-86 Oxine, with Biopsy and FACS Analysis for Tracking in Vivo Migration Patterns of Different Preparations of DC from a Single Donor

Author

Harrison, Si mon J., primary, Thompson, Mick, primary, Wall, Dominic, primary, Loudovaris, Maureen, primary, Mackensen, Andreas, primary, Bartholeyns, Jacques, primary, Ferrantini, Maria, primary, Santodonato, Laura, primary, Felzmann, Thomas, primary, Hicks, Rod, primary, Prince, H. Miles, primary, and Ritchie, David, primary

Published
2008
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16. PLAY LIKE A WINNER.

Author

Wall, Dominic

Abstract

An excerpt from the book "Golf Excellence" by Dominic Wall is presented.

Published
2008

17. Autologous Peripheral Blood T Lymphocytes Transduced with An Anti LewisY Chimeric Receptor Gene Persist In Patients with LewisyPositive Acute Myeloid Leukaemia and Show Changes In Functional Polarization After Adoptive Transfer,

Author

Neeson, Paul, Khot, Amit S, Peinert, Stefan, Tai, Tsin Y, Chen, Karen, Tainton, Kellie, Wall, Dominic, Hoenemann, Dirk, Kershaw, Michael H, Westwood, Jennifer, Trapani, Joe, Smyth, Mark J, Darcy, Phillip, Scott, Andrew, Kravets, Lucy, Davison, Jill, Dickinson, Michael J., Ritchie, David, and Prince, Miles

Abstract

Abstract 4180This icon denotes a clinically relevant abstract

Published
2011
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19. Peripheral Blood CD34+ Cell Enumeration as a Predictor of Apheresis Yield: An Analysis of More Than 1,000 Collections

Author

Gambell, Peter, Herbert, Kirsten, Dickinson, Michael, Stokes, Kerrie, Bressel, Mathias, Wall, Dominic, Harrison, Simon, and Prince, H. Miles

Subjects
*HEMAPHERESIS, *PROGENITOR cells, *LEUCOCYTES, *BODY weight, *GRANULOCYTE colony stimulating factor receptor, *MYELODYSPLASTIC syndromes, *MYELOPROLIFERATIVE neoplasms
Abstract

The role of the peripheral blood (PB) CD34+ cell count in predicting the CD34+ cell yield in hematopoietic progenitor cell apheresis collections is well established. However, sometimes unexpectedly poor CD34+ cell yields are obtained. To determine the effect, if any, of a range of factors on the ability of the PB CD34+ count to predict collection CD34+ cell count, we performed a retrospective analysis on consecutive hematopoietic progenitor cell apheresis collections between 2004 and 2008. Factors investigated included mobilization regimen, PB white blood cell count, body weight, and disease. After exclusion of collections involving apheresis complications, a total of 1,225 PB CD34+ cell results with corresponding collection CD34+ cell results from 458 patients were analyzed. Although differences in the median PB CD34+ cell counts and collection CD34+ cell counts were seen between mobilized collections with chemotherapy plus granulocyte colony-stimulating factor and those with granulocyte colony-stimulating factor alone, the predictive capability of the PB CD34+ cell count for the collection CD34+ cell yield remained similar. Although poorer collection efficiencies were observed in the myelodysplastic syndrome/myeloproliferative disorder diagnostic subgroup, our findings confirm that PB CD34+ cell analysis remains a powerful and irreplaceable tool for predicting hematopoietic progenitor cell apheresis CD34+ cell yield. [Copyright &y& Elsevier]

Published
2012
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