1. RENEB/EURADOS field exercise–the dicentric chromosome assay (DCA)-a valuable tool in emergency situations
- Author
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Endesfelder, David, Oestreicher, Ursula, Kulka, Ulrike, Ainsbury, Elizabeth, Moquet, Jayne, Grégoire, Eric, Trompier, Francois, Woda, Clemens, Waldner, Lovisa, Beinke, Christina, Vral, Anne, Barquinero, Joan Francesco, Sommer, Sylwester, Montoro, Alegria, Milic, Mirta, and Port, Matthias
- Subjects
ionizing radiation ,dicentric chromosome - Abstract
Depending on the ionising radiation exposure scenario, different biological or physical assays or combinations of these assays will be required to successfully recover the scenario and to obtain reliable dose estimates to aid medical decision making for the treatment of potentially exposed individuals. Interlaboratory comparisons (ILCs) are a central tool to validate and improve the performance of methods and laboratories. In most cases, such ILCs are performed under laboratory conditions where the influence of fixed parameters contributing to the uncertainty budget can be minimized. However, in a real-life scenario, the situation is much more complicated and it is therefore crucial to validate methods and laboratory responses under more realistic conditions.
- Published
- 2021