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1. Efficacy of a Multicomponent Positive Psychology Self-Help Intervention: Study Protocol of a Randomized Controlled Trial

Author

Schotanus-Dijkstra, Marijke, Drossaert, Constance HC, Pieterse, Marcel E, Walburg, Jan A, and Bohlmeijer, Ernst T

Subjects
Medicine, Computer applications to medicine. Medical informatics, R858-859.7
Abstract

BackgroundPositive psychology interventions have been found to enhance well-being and decrease clinical symptomatology. However, it is still unknown how flourishing can also be increased. Although multicomponent interventions seem to be necessary for this purpose, different formats can be used. A cost-effective approach could be a positive psychology-based self-help book with tailored email support to reach large target groups and to prevent dropout. ObjectiveThis study will evaluate the efficacy of a comprehensive multicomponent self-help intervention with or without email support on well-being and flourishing, and will seek to determine the working mechanisms underlying the intervention. MethodsIn this 3-armed, parallel, randomized controlled trial, 396 participants with low or moderate levels of well-being and without clinical symptomatology will be randomly assigned to (1) a self-help book condition with weekly email support, (2) a self-help book condition without email support but with a weekly information email, or (3) a waiting list control condition. Online measurements will be assessed at baseline, at post-test (3 months after baseline), and at 6 and 12 months after baseline. ResultsThe primary outcomes are well-being and flourishing (ie, high levels of well-being). Secondary outcomes are the well-being components included in the intervention: positive emotion, use of strengths, optimism, self-compassion, resilience, and positive relations. Other measures include depressive and anxiety symptoms, personality traits, direct medical and non-medical costs, life-events, and client satisfaction. ConclusionsThis study will add knowledge to the efficacy and cost-effectiveness of a multicomponent positive psychology intervention. We will also explore who can benefit most from this intervention. If the intervention is found to be effective, our results will be especially relevant for public mental health services, governments, and primary care. Trial RegistrationThe Netherlands Trial Register NTR4297; http://www.trialregister.nl/trialreg/admin/rctview.asp?TC=4297 (Archived by WebCite at http://webcitation.org/6Uwb5SUUM).

Published
2015
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6. A CRITICAL REVIEW OF PHARMACOECONOMIC STUDIES OF ACAMPROSATE

Author

POLDRUGO, FLAVIO, HAEGER, DORIS-ANITA, COMTE, SYLVIE, WALBURG, JAN, PALMER, ANDREW J., POLDRUGO, FLAVIO, HAEGER, DORIS-ANITA, COMTE, SYLVIE, WALBURG, JAN, and PALMER, ANDREW J.

Abstract

Aims: This review assessed the published data on the cost-effectiveness of acamprosate for the treatment of alcohol dependence. Methods: Four Markov modelling studies have assessed the therapeutic benefit and economic impact of acamprosate on the treatment of alcohol dependence. These have evaluated both short-term and long-term outcomes and have used German, Belgian, and Spanish costings. A fifth prospective cohort study collected real outcomes and data on expenditure during a 1 year study follow-up period. Results: All five studies have produced consistent results, showing the use of acamprosate, which enhances abstinence rates, to reduce the total costs of treatment and thus be dominant over other rehabilitation strategies not involving pharmacotherapy. In all of the studies, the principal cost-driver is hospitalization. Although there is a short-term increase in treatment costs associated with drug acquisition, these are recovered from long-term savings attributable to reduced hospitalization and rehabilitation costs

Published
2017

8. De Sterke-kanten-benadering: Persoonlijke Kwaliteiten als Hefboom voor Verandering

Author

Hiemstra, Djoerd, Bohlmeijer, Ernst Thomas, Bohlmeijer, Ernst, Bolier, Linda, Westerhof, Gerben, Walburg, Jan Auke, and Faculty of Behavioural, Management and Social Sciences

Subjects
IR-88934, METIS-300352
Abstract

Hoe kunnen we mensen helpen om hun functioneren, prestaties, gezondheid en welbevinden te verbeteren? De sterke-kanten-benadering biedt een inspirerende aanpak voor persoonlijke en professionele ontwikkeling, die zowel in de zorg, in het onderwijs, als in het personeelsmanagement kan worden toegepast. De kern van deze benadering is dat niet de problemen, gebreken en tekortkomingen, maar juist de successen, persoonlijke kwaliteiten en sterke kanten van mensen het vertrekpunt vormen voor verandering. In dit hoofdstuk bespreken we de basisfilosofie, de theorie, de empirische onderbouwing en de praktische toepassing van deze positief-psychologische veranderingsmethodiek.

Published
2013

11. A CRITICAL REVIEW OF PHARMACOECONOMIC STUDIES OF ACAMPROSATE

Author

POLDRUGO, FLAVIO, HAEGER, DORIS-ANITA, COMTE, SYLVIE, WALBURG, JAN, PALMER, ANDREW J., POLDRUGO, FLAVIO, HAEGER, DORIS-ANITA, COMTE, SYLVIE, WALBURG, JAN, and PALMER, ANDREW J.

Abstract

Aims: This review assessed the published data on the cost-effectiveness of acamprosate for the treatment of alcohol dependence. Methods: Four Markov modelling studies have assessed the therapeutic benefit and economic impact of acamprosate on the treatment of alcohol dependence. These have evaluated both short-term and long-term outcomes and have used German, Belgian, and Spanish costings. A fifth prospective cohort study collected real outcomes and data on expenditure during a 1 year study follow-up period. Results: All five studies have produced consistent results, showing the use of acamprosate, which enhances abstinence rates, to reduce the total costs of treatment and thus be dominant over other rehabilitation strategies not involving pharmacotherapy. In all of the studies, the principal cost-driver is hospitalization. Although there is a short-term increase in treatment costs associated with drug acquisition, these are recovered from long-term savings attributable to reduced hospitalization and rehabilitation costs

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