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Nurturing a low-carbon residential building stock requires businesses to create new solutions for markets. Wood material-based retrofits would be one solution but have remained rare in the urban context. Our study explores the structure and dynamics of an emerging business ecosystem (BE) of wooden retrofits in Finland. We study wooden retrofit projects, from the perspective of the initial steps of local-level development. By applying the concepts of BE and dynamic capabilities, we aim to shed light on the role of actors and their early-stage decision-making and use actor mapping and qualitative analysis of 27 thematic interviews with retrofit businesses and municipal actors. Results show that project initiation has relied on individual champions seizing opportunities as a main base in building dynamic capabilities. Builders and customers are key actors of wooden retrofit projects in local BEs in Finland. The identified actors are further involved with future plans for wooden retrofits, some with ambitious deep renovation with wood. Motivations for projects are driven from urban densification strategies, improvement of suburban neighborhood attractiveness and from the efficiency of space utilization. Results further elaborate a certain degree of difficulty in the early-stage decision-making. This study contributes to the scientific knowledge of both the BE and the dynamic capability perspective by exploring a path to material-driven sustainable construction in the Finnish context. We provide new information on this emerging retrofit construction business with potentially significant international implications if scaled up more widely.

Few studies have investigated the processes and strategic interactions among the Wooden Multistory Construction (WMC) industry actors, its customers, and local policymakers. Further insights into this field are needed for a sustainability transition in the construction sector. This study aims to explain WMC’s corporate sustainability strategies for co-creation with customers and municipalities. This was based on interviews with key informants in the sector and WMC actors using three case studies in Sweden. Our interviews focused on business processes, interactions with users and municipalities, sustainability, and innovation in the WMC market. The findings reflect the notion of a slow transition in the Swedish WMC market toward using more wood as a bearing structure, which is supported by the competitive advantages and climate performance of wood. The three case studies indicated that the corporate focus is currently placed on incremental improvements in operations, price competitiveness, and successful project management. However, in contexts where wood construction is seen as a unique advantage, collaborations between the construction industry and end users have developed and served as novel platforms for WMC market development. The study concludes that WMCl growth hinges on the industry’s housing offerings prioritizing quality, affordability, and swift construction.

Abstract Background . Decreased work ability due to mental disorders is a growing concern in Europe. We studied the role of work-family conflicts in association with long-term sickness absence due to mental disorders (LTSA-MD). Methods . Baseline data were extracted from the Helsinki Health Study for women aged 40 to 55 in full-time work in 2001 − 2002 (N = 2386). Questionnaire responses were linked with register data from the Social Insurance Institution of Finland on SA spells due to mental disorders during 2004–2010. We studied an overall question on satisfaction with combining work and family (WFS) and composite scores of work-to-family conflicts (WTFC) and family-to-work-conflicts (FTWC), and their components in association with the first certified SA spell (≥ 12 calendar days) due to a mental disorder during the follow-up. We performed Cox regression analyses with hazard ratios (HR) and their 95% confidence intervals (CI) adjusted for sociodemographic factors, work schedule, perceived mental and physical strenuousness at work, and self-rated health. First, we examined all participants, and second, only those who reported no prior mental disorder. Results . Poor work-family satisfaction (WFS) was associated with subsequent LTSA-MD, adjusting for all covariates (HR 1.60; 95% CI 1.10–2.16). Both high WTFC (1.64; 1.15–2.23), and high FTWC (1.43; 1.02–2.00) increased the probability of LTSA-MD in the full model. When participants with prior mental disorder were excluded, the association between poor WFS and WTFC with LTSA-MD retained while that between FTWC and LTSA-MD attenuated; however, two items of the FTWC were still associated with LTSA-MD: ‘Family worries and problems distract you from your work’ and ‘Family matters prevent you from sleeping enough to do your job well’. Of the WTFC items, the following remained associated with LTSA-MD: ‘Problems at work make you irritable at home’ and ‘Your job takes so much energy you do not feel up to doing things that need attention at home’. The experience of decreased time for work or family did not associate with LTSA-MD. Conclusions . Among female municipal employees, dissatisfaction with combining work and family and both work-to-family and family-to-work conflicts were associated with subsequent long-term sickness absence due to mental disorders.

Unmanned Aircraft Systems-relevant education is a rapidly evolving domain-specific topic that needs wide expertise in ICT. That kind of topic is very difficult for a single research group to gain overall competence and keep the courses updated within a rapidly evolving education topic. This paper gives an overview of the education and research activities of Finnish universities that are members of the UAS (Drone) University Collaboration Network project funded by the Finnish Ministry of Education, Science and Culture.

Using wood in multistory apartment construction (WMC) has a climate-positive advantage with buildings acting as long-term carbon storage. Business ecosystem (BE) development around WMC is needed to accelerate the adoption of wooden materials in the conservative construction industry. As the business actors around WMC are essentially different from those using other building materials, new knowledge must be built from the project level. This study uses a qualitative interview approach among actors from three pioneering urban building projects to address their perceptions of building with wood regarding a project-based BE. Based on the thematic analysis, sources of both tangible and intangible value creation were found to arise from building with wood. A higher degree of prefabrication associated with WMC was seen in all projects to influence the reorganization of logistics, enabling faster building processes and lean material use. No strong sustainability-driven culture could be identified in any of the projects. Results further flag the sensitivity and importance of management and coordination skills in targeting improvements of the construction business based on WMC. In the bigger picture, there is still room for further research at regional and global level on business model changes in building with this renewable and recyclable material.

Abstract Tea should be perceived more as a cultural product than a fast-moving consumer good with its roots deep in different cultures across nations. Nevertheless, consumer demands on tea have not been explored sufficiently from a cultural perspective. This research aims to examine motives that are driving Chinese tea consumption on two usage occasions, under the influence of the Chinese renqing, mianzi, collectivism, and man-nature unity culture. Linkage was established between Chinese culture and consumer motives. The factor analysis on 280 respondents identified five consumer psychological motives. Further logistic regression analysis suggested consumer motives and usage situations were related. The contribution of the findings is summarized. On one hand, this study adds to the limited understandings on consumer motives of tea in an emerging country from the cultural aspect. On the other hand, deep understandings of brand chasing, sustainability, and pragmatism motives should businesses to better serve consumers.

This study examines the role of business organizations in co-governing biodiversity and ecosystem services (BES) using a phenomenon-based approach and bridging business management literature, ecosystem services literature and environmental governance literature. The empirical analysis includes twelve Nordic forest corporations considered market leaders in Finland, Sweden and Norway. Using content analysis of corporate sustainability reports and managerial interviews, we recorded 127 company-led measures addressing BES and we categorized them into seventeen types (e.g., land use planning and restoration, mobilization of financial resources for conservation, partner auditing, capacity building and consultation with stakeholders). For each BES measure, we also identified the BES issues being addressed (e.g., climate regulation, soil maintenance, cultural values); company motivation (i.e., compliance, strategic, profit-seeking); the stakeholders/beneficiaries involved (e.g., employees, forest owners, experts, local communities, public administration, NGOs); and the private governance instruments used for implementing the measure (i.e., regulatory, economic, information and rights-based instruments). The findings suggest that practices such as monetary valuation, biodiversity offsets and green bonds are emerging as profitable or strategically interesting options for Nordic forest companies. However, well-established practices, such as forest inventory, partner auditing and land sparing, continue to be the backbone of private BES governance among the leading companies examined. Although not directly motivated by compliance, private governance measures are largely nested in legislation. The contribution of this study includes reflections of relevance for both the scholarly and managerial realms. From a scholarly perspective, we further elaborate an understanding of BES management and governance from an organizational perspective. From a managerial perspective, we provide and discuss an overview of potential measures that forest companies can implement to address biodiversity and other socio-ecological issues at the land-use level.

Climate change sets high pressures on the construction industry to decrease greenhouse gas emissions. Due to the carbon storage properties and potential to use renewable resources efficiently, wooden multi-storey construction (WMC) is an interesting alternative for the construction industry to enhance sustainable development combined with the aesthetic and well-being benefits of wood perceived among many consumers. For forest industry firms, industrial wood construction is a possibility to seek for business opportunities and bring socio-economic benefits for local economies. Despite positive drivers, WMC still remains a niche even in the forest-rich countries.The purpose of our study is to add understanding on the WMC market development by conducting a systematic literature analysis on international peer-reviewed studies from the past 20 years. Our special focus is on the role of WMC in the housing markets studied from the perspectives of the demand, supply and local governance factors. As specific aims, we 1) synthesize the key barriers and enabling factors for the WMC market growth; 2) identify the actors addressed in the existing studies connected to the WMC market development, and 3) summarize research methods and analytical approaches used in the previous studies. As a systematic method to make literature searches in Web of Science and Scopus for years 2000â2020, we employed PRISMA guidelines. By using pre-determined keywords, our searches resulted in a sample of 696 articles, of which 42 full articles were after selection procedure included in-depth content analysis. Our results showed cost-efficiency gains from industrialized prefabrication and perceived sustainability benefits by consumers and architects enabled a WMC market diffusion. The lack of experiences on the WMC, and path dependencies to use concrete and steel continue to be key barriers for increased WMC. Although our research scope was the global WMC market development, most of the literature concerned the Nordic region. The key actors covered in the literature were businesses (e.g., contractors, manufacturers and architects) involved in the wood construction value-chains, while residents and actors in the local governance were seldomly addressed. Currently, case studies, the use of qualitative data sets and focus on the Nordic region dominate the literature. This hinders the generalizability of findings in different regional contexts. In the future, more research is needed on how sustainability-driven wood construction value-chains are successfully shaping up in different geographical regions, and how they could challenge the dominant concrete-based construction regime.

Purpose: A systematic review of the literature on circular business models was performed, for synthesis of what it reveals about the role and value of data in those models. The increasing quantity of supply-chain and life-cycle data available has potential to be a signifi­cant driver of circular business models. The paper describes the current state of knowledge and identifies avenues for further research related to use of various forms of data in the models. Design: A systematic review of literature on the use of data in circular business models was carried out, to inform understanding of the existing body of knowledge and provide a firm foundation for further research. Findings: The literature reviewed indicates that the understanding of the role and value of data in circular business models is fragmented. Nonetheless, data and related technologies, services, and platforms are commonly seen as drivers and enablers of circular economy. Among the further research opportunities are work on collaboration in capturing the value of data in circular business models and on data as a source of business-model innovation. Value: The work provides new insight on transforming data-driven value creation into good business and represents one of the first comprehensive reviews addressing data’s value in a networked circular-economy context. It aids in understanding what data-driven circular business models enable, how companies can create new circular business, and how the emergence of such networked business can be accelerated.

The long-term impact of viruses residing in the human bone marrow (BM) remains unexplored. However, chronic inflammatory processes driven by single or multiple viruses could significantly alter hematopoiesis and immune function. We performed a systematic analysis of the DNAs of 38 viruses in the BM. We detected, by quantitative PCRs and next-generation sequencing, viral DNA in 88.9% of the samples, up to five viruses in one individual. Included were, among others, several herpesviruses, hepatitis B virus, Merkel cell polyomavirus and, unprecedentedly, human papillomavirus 31. Given the reactivation and/or oncogenic potential of these viruses, their repercussion on hematopoietic and malignant disorders calls for careful examination. Furthermore, the implications of persistent infections on the engraftment, regenerative capacity, and outcomes of bone marrow transplantation deserve in-depth evaluation.

In this article, we have presented the teaching, research, and development-related activities on unmanned aircraft systems (UAS) carried out at the Savonia University of Applied Sciences. We aim to demonstrate a few applications such as snow-depth measurement, mapping of gas leaks and operation of bio-waste composting pits, and the feasibility study for installing bird warning balls on the power grids. Also, we have highlighted the major ongoing UAS project activities, education, and future directions.

Human bocavirus 1 (HBoV1), a common pediatric respiratory pathogen, can persist in airway secretions for months hampering diagnosis. It also persists in tonsils, providing potential reservoirs for airway shedding, with the exact location, host cell types, and virus activity unknown.

So far, consumer housing values have not been addressed as factors affecting the market diffusion potential of multi-storey wood building (MSWB). To fill the void, this study addresses different types of consumer housing values in Denmark, Finland, Norway, and Sweden (i.e., Nordic region), and whether they affect the likelihood of prejudices against building with wood in the housing markets. The data collected in 2018 from 2191 consumers in the Nordic region were analyzed with exploratory factor analysis and logistic binary regression analysis. According to the results, consumersâ perceptions on ecological sustainability, material usage and urban lifestyle were similar in all countries, while country-specific differences were detected for perceptions on aesthetics and natural milieus. In all countries, appreciating urban lifestyle and living in attractive neighborhoods with good reputation increased the likelihood of prejudices against wood building, while appreciation of aesthetics and natural milieus decreased the likelihood of prejudices. In strengthening the demand for MSWB and sustainable urbanization through actions in businesses (e.g., branding) and via public policy support (e.g., land zoning), few messages derive from the results. In all, abreast with the already existing knowledge on the supply side factors (e.g., wood building innovations), more customized information is needed on the consumer-driven issues affecting the demand potential of MSWB in the housing markets. This would enable, e.g., both enhancing the supply of wooden homes for consumers appreciating urban lifestyle and neighborhoods and fortifying positive image of wood among consumers especially appreciating good architecture and pleasant environmental milieus.

ABSTRACT Infections with the nine human herpesviruses (HHVs) are globally prevalent and characterized by lifelong persistence. Reactivations can potentially manifest as life-threatening conditions for which the demonstration of viral DNA is essential. In the present study, we developed HERQ-9, a pan-HHV quantitative PCR designed in triplex reactions to differentiate and quantify each of the HHV-DNAs: (i) herpes simplex viruses 1 and 2 and varicella-zoster virus; (ii) Epstein-Barr virus, human cytomegalovirus, and Kaposi’s sarcoma-associated herpesvirus; and (iii) HHV-6A, -6B, and -7. The method was validated with prequantified reference standards as well as with mucocutaneous swabs and cerebrospinal fluid, plasma, and tonsillar tissue samples. Our findings highlight the value of multiplexing in the diagnosis of many unsuspected, yet clinically relevant, herpesviruses. In addition, we report here frequent HHV-DNA co-occurrences in clinical samples, including some previously unknown. HERQ-9 exhibited high specificity and sensitivity (LOD95s of ∼10 to ∼17 copies/reaction), with a dynamic range of 101 to 106 copies/μl. Moreover, it performed accurately in the coamplification of both high- and low-abundance targets in the same reaction. In conclusion, we demonstrated that HERQ-9 is suitable for the diagnosis of a plethora of herpesvirus-related diseases. Besides its significance to clinical management, the method is valuable for the assessment of hitherto-unexplored synergistic effects of herpesvirus coinfections. Furthermore, its high sensitivity enables studies on the human virome, often dealing with minute quantities of persisting HHVs. IMPORTANCE By adulthood, almost all humans become infected by at least one herpesvirus (HHV). The maladies inflicted by these microbes extend beyond the initial infection, as they remain inside our cells for life and can reactivate, causing severe diseases. The diagnosis of active infection by these ubiquitous pathogens includes the detection of DNA with sensitive and specific assays. We developed the first quantitative PCR assay (HERQ-9) designed to identify and quantify each of the nine human herpesviruses. The simultaneous detection of HHVs in the same sample is important since they may act together to induce life-threatening conditions. Moreover, the high sensitivity of our method is of extreme value for assessment of the effects of these viruses persisting in our body and their long-term consequences on our health.

Metsäalan työmarkkinat ovat muutoksessa, ja työntekijöiltä odotetaan tulevaisuudessa entistä monipuolisempia taitoja. Tämä yhdessä ikäluokkien pienenemisen kanssa ennakoi kovenevaa kilpailua osaavista työntekijöistä myös metsäalalla, jolla työvoimatarpeen on pääsääntöisesti arvioitu kasvavan. Tässä tutkimuksessa selvitettiin suomalaisten 17–18-vuotiaiden nuorten suhtautumista työuraan metsäalalla ja alan houkuttelevuuteen työnantajana. Tulosten perusteella metsäalalla on mahdollisuus rekrytoida alasta kiinnostuneita työntekijöitä myös tulevaisuudessa. Kiinnostus toimialaa kohtaan on kuitenkin edelleen jossain määrin sukupuolittunutta, sillä miehistä reilu puolet, mutta naisista vain reilu kolmannes, uskoi, että omalla kohdalla hyvä työpaikka voisi löytyä metsäalalta. Yleisesti vastaajia kiinnostivat erityisesti erilaiset asiantuntijuuteen liittyvät työtehtävät sekä työtehtävät uusien tuotteiden kehittämisen parissa. Työssä tärkeiksi asioiksi katsottiin mielekkyyden, palkan ja työyhteisön lisäksi myös työn merkityksellisyys. Metsäbiotalouden tulevaisuuden osalta suurin osa vastaajista arvioi, että kymmenen vuoden kuluttua kestävyyskysymykset nousevat tärkeämmiksi nykytilaan verrattuna.

Abstract Background In the past few years, eleven new human viruses have joined the two previously known members JCPyV and BKPyV of the Polyomaviridae family, by virtue of molecular methods. Serology data suggest that infections with human polyomaviruses (HPyVs) occur since childhood and the viruses are widespread in the general population. However, the viral persistence sites and transmission routes are by and large unknown. Our previous studies demonstrated that the four new HPyVs – KIPyV, WUPyV, MCPyV and TSPyV – were present in the tonsils, and suggested lymphoid tissue as a persistent site of these emerging human viruses. We developed a Luminex-based multiplex assay for simultaneous detection of all 13 HPyVs known, and explored their occurrence in tonsillar tissues of children and adults mostly with tonsillitis or tonsillar hypertrophy. Methods We set up and validated a new Luminex-based multiplex assay by using primer pairs and probes targeting the respective HPyV viral protein 1 (VP1) genes. With this assay we tested 78 tonsillar tissues for DNAs of 13 HPyVs. Results The multiplex assay allowed for simultaneous detection of 13 HPyVs with high analytical sensitivity and specificity, with detection limits of 100–102 copies per microliter, and identified correctly all 13 target sequences with no cross reactions. HPyV DNA altogether was found in 14 (17.9%) of 78 tonsils. The most prevalent HPyVs were HPyV6 (7.7%), TSPyV (3.8%) and WUPyV (3.8%). Mixed infection of two HPyVs occurred in one sample. Conclusions The Luminex-based HPyV multiplex assay appears highly suitable for clinical diagnostic purposes and large-scale epidemiological studies. Additional evidence was acquired that the lymphoid system plays a role in HPyV infection and persistence. Thereby, shedding from this site during reactivation might take part in transmission of the newly found HPyVs.

The cell type that hosts parvovirus B19 (B19V) DNA lifelong is currently unknown. Here, the authors identify tonsillar B cells as a reservoir, detect an extinct B19V type in older adults, supporting a long-term association, and show that B19V uptake into B cells is antibody dependent.

Bioeconomy development will create new opportunities for firms operating in the international wood products markets, and identifying and exploiting these opportunities is emphasized as a key concept to achieving business success. Our study will attempt to address a gap in the literature on sawmill industry business development from the viewpoint of international opportunity recognition. The aim of our study is to provide a holistic description on how small and medium-sized enterprises (SMEs) in the wood products industry recognize and exploit international business opportunities, and how they utilize network perspectives in this context. The subject was examined through Finnish wood product industry SMEs by interviewing 11 managers and industry representatives. The results suggest that SMEs recognize international opportunities reactively per se. Social networks formed in professional forums were an important information channel for identifying international opportunities. Through vertical business networks, such as sales agents, firms have been able to increase their international market presence and free their own resources for other important activities. Horizontal dyadic business networks were seen to facilitate new international opportunities through cooperation, while excessive reliance on vertical networks raised concerns and seemed not to be effective in international opportunity recognition. Institutional networks formed a systematic way of recognizing international opportunities, but more so at the initial market entry stage.

Tutkimuksessa selvitettiin työn ja muun elämän yhteensovittamisen käytäntöjä ja kulttuuria työorganisaatioiden näkökulmasta. Tavoitteena oli luoda tilannekuva suomalaisten työpaikkojen työn ja muun elämän yhteensovittamista tukevien käytäntöjen ja kulttuurin esiintymiseen sekä selvittää yhteyttä käytäntöjen ja työpaikan luonteen sekä työ-elämä -kulttuurin välillä. Tutkimuksen kohteena olivat kaikki yli 10 työntekijän suomalaiset työpaikat, joiden työsuojelupäälliköille ja -valtuutetuille lähetettiin sähköinen kysely lokakuussa 2015. Kyselyyn vastasi 2715 työsuojeluhenkilöä 2345 työpaikalta. Työn ja muun elämän yhteensovittamista tukevia käytäntöjä ja kulttuuria tarkasteltiin työnantajasektorin, toimialan, työpaikan koon, sukupuoli- ja ikäjakauman mukaan. Tulokset osoittivat, että työn ja muun elämän yhteensovittamista tukevat käytännöt ja kulttuuri vaihtelivat työpaikan taustatekijöiden mukaan. Erityisesti naisvaltaisilla ja pienillä työpaikoilla työ-elämä -kulttuuri oli myönteinen. Kulttuuriltaan myönteisillä työpaikoilla oli myös enemmän työn ja muun elämän yhteensovittamista tukevia käytäntöjä, niitä seurattiin, niistä tiedotettiin ja niihin liittyviä tavoitteita oli useammin kirjattu strategiaan tai suunnitelmiin. Yleisesti ottaen työpaikoilla on vielä paljon hyödyntämättömiä mahdollisuuksia kehittää työn ja muun elämän yhteensovittamisen käytäntöjä.