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Dengue encephalitis is considered as a severe but unusual clinical presentation of dengue infection. Limited molecular information is available on the neurotropism of dengue virus (DENV), highlighting the need for further research. During a dengue outbreak in Vietnam in 2013, two DENV-3 strains were isolated, in which one was isolated from cerebrospinal fluid (CSF) samples from a dengue encephalitis patient and another strain was isolated from a patient with classical dengue fever in Hai Phong, Vietnam. DENV serotype-3 (DENV-3) isolated from these samples belonged to genotype III, marking the first report of this genotype in the country at that time. Genetic variation between both strains was elucidated by using a full genome sequencing by next-generation sequencing (NGS). The infectivity of the isolated DENV-3 strains was further characterized using human and mouse neuronal cell lines. Phylogenetic analysis of the isolates demonstrated high homogeneity between the CSF-derived and serum-derived DENV-3, in which the full genome sequences of the CSF-derived DENV-3 presented a Thr-1339-Ile mutation in the nonstructural 2A (NS2A) protein. The CSF-derived DENV-3 isolate grew preferentially in human neuronal cells, with a significant proportion of cells that were positive for nonstructural 1 (NS1), nonstructural 4B (NS4B), and nonstructural 5 (NS5) antigens. These results suggest that NS2A may be a crucial region in the neuropathogenesis of DENV-3 and its growth in human neuronal cells. Taken together, our results demonstrate that a CSF-derived DENV-3 has unique infectivity characteristics for human neuronal cells, which might play a crucial role in the neuropathogenesis of DENV infection., Canadian Journal of Infectious Diseases and Medical Microbiology, 2023, art. no. 2635383; 2023

Supplemental material, sj-docx-1-npx-10.1177_1934578X221148621 for Two New Nitrogen-Containing Glycosides From Stixis scandens by Tran Thi Yen, Nguyen Thanh Tam, Nguyen Thanh Thi Kim and Vo Ngoc Binh, Nguyen Thao Kim Nu, Ngo Quoc Anh in Natural Product Communications

We revisit a model describing Seebeck effect on a weak link between two charge Kondo circuits, which has been proposed in the [Phys. Rev. B 97, 085403 (2018)]. We calculate the thermoelectric coefficients in the perturbation theory assuming smallness of the reflection amplitudes of the quantum point contacts. We focus on the linear response equations for the heat conductance in three different scenarios as: Fermi liquid vs Fermi liquid, Fermi liquid vs non-Fermi liquid, nonFermi liquid vs non-Fermi liquid. The oscillations of the heat conductance as a function of the gate voltage of each quantum dot are analysed in both Fermi liquid and non-Fermi liquid regimes. We discuss possible experimental realizations of the model to observe the signatures of the non-Fermi liquid behaviour in the heat conductance measurements., Comment: 12 pages, 2 figures

Porcine epidemic diarrhea virus (PEDV) causes diarrhea in pigs leading to severe illnesses and high mortality rates. The development of medicinal agents to treat PEDV infection is therefore crucial. In this study, antiviral activities against PEDV of ethanol and aqueous extracts of 17 Vietnamese traditional medicinal plants were evaluated using the cytopathic effect-based assay. The results showed that 14 out of 17 medicinal plants could inhibit the cytopathic effect of PEDV. The ethanol extract of Stixis scandens was identified as the most active extract with its MIC (minimum inhibitory concentration) being 0.15 μg/mL. Other plant extracts also displayed strong antiviral activity against PEDV, including Anisomeles indica, Pericampylus glaucus and Croton kongensis. The results demonstrate that certain medicinal plants have a high antiviral potential and may serve as a lead to develop novel pharmaceutical agents to cure PED as well as the diseases caused by other coronaviruses.

Breast cancer (BC) is the leading type of cancer among women. Findings have revolutionized current knowledge of microRNA (miRNA) in breast tumorigenesis. The seed region of miRNA regulates the process of gene expression negatively. The presence of SNPs in the seed regions of miRNA dramatically alters the mature miRNA function. Additionally, SNPs in the out-seed region of miRNAs have a significant impact on miRNA targeting. This study focuses on the in silico analysis procedure of mature miRNA SNPs and their impact on BC risk. The database annotated SNPs on mature miRNAs was used. Also, target gene alterations, miRNAs function in BC, and the interaction of miRNAs with targets were predicted. A list of 101 SNPs in 100 miRNAs with functional targets in BC was indicated. Under the SNPs allele variation, 10 miRNAs changed function, 6 miRNAs lost targets, 15 miRNAs gained targets, 48 onco-miRNAs remained unchanged, and 21 tumor suppressor miRNAs remained unchanged. At last, a list of 89 SNPs, which alter miRNA function and miRNA-mRNA interaction, were shown to be potentially associated with BC risk. This research theoretically generated a list of possible causative SNPs in the mature miRNA gene that might be used in future BC management studies.

In Vietnam, fisheries play a key role in the national economy. Helminth infections in fish have a major impact on public health and sustainable fish production. A comprehensive summary of the recent knowledge on fish helminths is important to understand the distribution of parasites in the country, and to design effective control measures. Therefore, a systematic review was conducted, collecting available literature published between January 2004 and October 2020. A total of 108 eligible records were retrieved reporting 268 helminth species, among which are digeneans, monogeneans, cestodes, nematodes and acanthocephalans. Some helminths were identified with zoonotic potential, such as, the heterophyids, opisthorchiids, the nematodes Gnathostoma spinigerum, Anisakis sp. and Capillaria spp. and the cestode Hysterothylacium; and with highly pathogenic potential, such as, the monogeneans of Capsalidae, Diplectanidae and Gyrodactylidae, the nematodes Philometra and Camallanidae, the tapeworm Schyzocotyle acheilognathi, the acanthocephalans Neoechinorhynchus and Acanthocephalus. Overall, these studies only covered about nine percent of the more than 2400 fish species occurring in the waters of Vietnam. Considering the expansion of the aquaculture sector as a part of the national economic development strategy, it is important to expand the research to cover the helminth fauna of all fish species, to assess their potential zoonotic and fish health impacts., Graphical abstract Image 1, Highlights • 268 helminth species were reported in 213 fish species occurring in Vietnam. • Reported zoonotic helminths belonged to digeneans, nematodes and cestodes. • Other species included monogeneans, nematodes, cestodes and acanthocephalans.

Breast cancer is the most common cancer for women around the world. The presence of single nucleotide polymorphisms (SNP) on or near the coding region of breast cancer susceptibility genes can affect the regulation of gene expression, which may increase or decrease the risk of breast cancer. BARX2 was showed to stimulate the expression of ERS1, which involved in the development of breast cancer. SNP rs7107217 on 152kb downstream of the BARX2 could affect the level of protein BARX2 and had been proved to associate with the breast cancer risk in populations similar to Vietnamese, including Chinese and Korean. In this study, rs7107217 was genotyped and initially detemined the association with the breast cancer risk in Vietnamese. Real-time PCR HRM was optimized and used to genotype rs7107217 in 117 breast cancer cases and 105 healthy controls. Thereafter, the correlation of this SNP with the risk of breast cancer was initially determined by analyzing the differences in allelic and genotypic frequencies between cases and control groups. The results showed the optimal rs7107217 genotyping condition was successfully developed with the high sensitivity, specificity, and consistency. SNP rs7107217 had high polymorphism with the frequency of minor allele C of 29.9% and 35.3% in case and control, respectively. SNP rs7107217 had been found no association with the breast cancer risk (C vs A: P = 0.23, OR (95% CI) = 0.79 (0.53 – 1.17)). However with the low reliability of the analysis (11.71%) and the high potential related to the formation of breast cancer, the association between rs7107217 and breast cancer risk in Vietnamese population should be further conducted on a larger sample size to get higher accuracy.

MicroRNAs (miRNAs) have been recently described as small noncoding RNAs that are involved in numerous crucial physiological processes, such as cell cycles, differentiation, development, and metabolism. Thus, dysregulation of these molecules could lead to several severe disorders, including breast cancer (BC). Ongoing investigations in malignant growth diagnostics have distinguished miRNAs as promising disease biomarkers. As with any other mRNAs, single nucleotide polymorphisms (SNPs) in DNA sequence encoding for miRNA (miR-SNPs) indeed lead to potential changes in the function of miRNA. In this study, miR-SNPs located in different miRNA sequence regions, which have been associated with BC in different ways, and the potential mechanisms of how these miR-SNPs develop the risk of the disease were discussed.

Breast cancer (BC) is the most common cancer among women and accounts for the highest mortality rates in the developing countries, including Vietnam. D-loop, is a non-coding region in mitochondrialcircular DNA molecules, related to control the replication and transcription of mitochondrial genes. D-loop mutations cause the dysfunction of the respiratory chain, which contributes to the process of BC. SNP rs3937033 (T/C) on D-loop was reported to have the association with BC in Europe America population (OR [95%CI]= 1.98 [1.25–3.12], P=0.036), and Caucasian (OR[95%CI]= 21 [2.15–204.6], P=0.003). In this study, the High Resolution Melting (HRM) method is optimized for genotyping 100/100 cases/controls samples, then to determine the association between the disease and this SNP. TT, TC and CC genotype frequencies in patient group (36 %, 3 % and 61 %) and control group (23 %, 1 % and 76 %) were calculated based on the results of genotyping by optimal HRM method with the annealing temperature is 66 0C. Association analysis result showed that T allele increases the risk of breast cancer patients up to 1.41 times (OR [95% CI] = 1.41 [1.3-1.92], Pallele = 0.03). Therefore, SNP rs3937033 could be a potential biomarker for early BC diagnosis in Vietnamese. However, this research needs to be conducted with a larger sample size to reach the greater confidence.

In this paper, SnO2 nano particles were loaded on TiO2 nanotubes (SnO2/TNTs) by onestep hydrothermal method with the purpose to enhance the photocatalytic ability of TiO2 nanotubes (TNTs). Structure and morphology of the material were characterized by X-ray diffraction measurement (XRD) and transmission electron microscopy (TEM). SnO2 nano particles onto TNTs prevent the recombination of electronhole pairs at the interface area. This contribution increased the photocatalytic efficiency of the material. The effect of SnO2 contents on the photocatalytic activities of the composite materials was also investigated with methylene blue that is chosen as the pollutant in industry. The results showed that SnO2/TNTs composite materials had been successfully synthesized by one-step hydrothermal method and SnO2/TNTs composite material with 2 % SnO2 content loading possesses the highest photocatalytic efficiency with 70 % after 180 minutes illuminated under sunlight.

Background An opisthorchiid liver fluke was recently reported from ducks (Anas platyrhynchos) in Binh Dinh Province of Central Vietnam, and referred to as “Opisthorchis viverrini-like”. This species uses common cyprinoid fishes as second intermediate hosts as does Opisthorchis viverrini, with which it is sympatric in this province. In this study, we refer to the liver fluke from ducks as “Opisthorchis sp. BD2013”, and provide new sequence data from the mitochondrial (mt) genome and the nuclear ribosomal transcription unit. A phylogenetic analysis was conducted to clarify the basal taxonomic position of this species from ducks within the genus Opisthorchis (Digenea: Opisthorchiidae). Methods Adults and eggs of liver flukes were collected from ducks, metacercariae from fishes (Puntius brevis, Rasbora aurotaenia, Esomus metallicus) and cercariae from snails (Bithynia funiculata) in different localities in Binh Dinh Province. From four developmental life stage samples (adults, eggs, metacercariae and cercariae), the complete cytochrome b (cob), nicotinamide dehydrogenase subunit 1 (nad1) and cytochrome c oxidase subunit 1 (cox1) genes, and near-complete 18S and partial 28S ribosomal DNA (rDNA) sequences were obtained by PCR-coupled sequencing. The alignments of nucleotide sequences of concatenated cob + nad1 + cox1, and of concatenated 18S + 28S were separately subjected to phylogenetic analyses. Homologous sequences from other trematode species were included in each alignment. Results Phylogenetic trees were inferred from concatenated (cob + nad1 + cox1) nucleotide sequences and combined 18S + 28S nucleotide sequences of five Opisthorchis sp. BD2013 samples and additional reference taxa. Both trees demonstrated the anticipated clustering of taxa within the superfamily Opisthorchioidea, the paraphyly of the genus Opisthorchis and the sister-species relationship of Opisthorchis sp. BD2013 with O. viverrini. Conclusions While it is likely that Opisthorchis sp. BD2013 is distinct from O. viverrini, it is clearly a sister taxon of O. viverrini within the limited number of Opisthorchis species for which appropriate sequence data are available. The new sequences provided here will assist the diagnosis and the taxonomic clarification of the opisthorchiid species.

We investigate theoretically quantum transport through the "charge" Kondo circuit consisting of the quantum dot (QD) coupled weakly to an electrode at temperature $T+\Delta T$ and connected strongly to another electrode at the reference temperature $T$ by a single-mode quantum point contact (QPC). To account for the effects of Coulomb interaction in the QD-QPC setup operating in the integer quantum Hall regime we describe the edge current in the quantum circuit by Luttinger model characterized by the Luttinger parameter $g$. It is shown that the temperature dependence of both electric conductance $G\propto T^{2/g}$ and thermoelectric coefficient $G_T\propto T^{1+2/g}$ detours from the Fermi-liquid (FL) theory predictions. The behaviour of the thermoelectric power $S=G_T/G\propto T$ in a regime of a single-channel Kondo effect is, by contrast, consistent with the FL paradigm. We demonstrate that the interplay between the mesoscopic Coulomb blockade in QD and weak repulsive interaction in the Luttinger Liquid $g=1-\alpha$ $(\alpha \ll 1)$ results in the enhancement of the thermopower. This enhancement is attributed to suppression of the Kondo correlations in the "charge" circuit by the destructive quantum interference effects., Comment: 10 pages, 2 figures

Breast cancer (BC), the most common type of cancer among women worldwide, is a polygenetic disease which is caused by the interaction of several genes. Understanding the genetic factors for early diagnosis of BC is crucial to ensure the survival of BC patients. MicroRNA 27a (miR-27a), an oncogenic miRNA, has been predicted to target on the tumor suppressor ZBTB10 that can regulate many processes of cell. Single nucleotide polymorphism (SNP) rs895819 alters the structure and function of miR-27a, which has been anticipated to reduce the risk of BC in different populations such as German and Chinese. This study aimes to investigate the relationship between the existence of SNP rs895819 (A>G) and the risk of BC using the optimized high resolution melting (HRM) method. 106 BC samples and 117 healthy samples were genotyped using an optimal HRM protocol then statistical analysis was applied to examine the relationship of the SNP. In the case group, the risk G allele accounted for 36 % while in the control group it took up 32 %. Statistic result revealed that rs895819 (A>G) had no significant relationship with the breast cancer (OR=1.119; P=0.46676) in given case-control samples. Although the SNP is significantly ralated with BC in German or Chinese populations, it is not a potential marker for diagnosis in the Vietnamese population. Further studies investigating relationship between rs895819 (A>G) and breast cancer in the Vietnamese population is not recommended. In future, other SNPs should be investigated with the aim of identification efficient biomarker for early diagnosis of BC in Vietnamese.

As the second most popular cancer in the world, breast cancer affects millions of people and causes a large number of deaths every year. Identifying the genetic marker is one of approaches of early diagnosis for following cancer and give a correct treatment. Many recent studies have shown several SNPs including rs10941679 (located at the uptream of MRPS30 gene) are strongly associated with breast cancer in European and other populations. The association between rs10941679 and breast cancer in Vietnamese population has been investigated in this study using High Resolution Melt (HRM) method as a tool for genotyping. HRM was designed on Umelt sofware and was optimized based on annealing temperature and MgCl2 concentration gradient in order to have 3 distinct melting curves from 3 genotypes of rs10941679. The optimal HRM conditions were selected with Tm=58 oC and MgCl2=3.0 mM and 100 Cases/control samples were genotyped by the optimimal HRM condition. The results showed that the frequency of the risk allele G in case and control group were 48.5 % and 54.0 %, respectively. Regression analysis on the presense of the risk allele and risk allele-containing genotypes has shown no association between rs10941679 and breast cancer in Vietnamese population (OR = 0.80; 95% CI = [0.54 – 1.19]; PG = 0.27; PGG/GA = 0.56). The power of this result was estimated to be 12.02 %. To obtain the power up to 90 %, the sample size up to 1691 cases/controls is needed. Due to its low posibility in the assocation with breast cancer in Vietnamese population, rs1094169 is not recommended for further study in finding the genetic for markers cancer in Vietnamese population.

Following the first report of Opisthorchis viverrini infection in a domestic duck in Phu My District of Binh Dinh Province, Central Vietnam, many other cases were observed in the province. We determined the infection rate and intensity of O. viverrini infection in ducks in 4 districts of the province. A total of 178 ducks were randomly selected from 34 farms for examination of flukes in the liver and gall bladder. An infection rate of 34.3% (range 20.7-40.4% among districts) was found; the intensity of infection was 13.8 worms per infected duck (range 1-100). These findings show the role of ducks as a host for O. viverrini, duck genotype, which is sympatric with the human O. viverrini genotype in this province. It also stresses the need for investigations on the zoonotic potential and the life cycle of this parasite.

The control of the aging conditions for the aluminium alloys has been considered as an effective strategy to improve the properties of the alloy, especially in enhancement of the corrosion resistance. In this study, a detailed investigation of the effect of one-stage (T6) and two-stage (T76x) aging temper on mechanical properties, exfoliation and intergranular corrosion behaviours of 7075 Al–Zn–Mg–Cu alloy was implemented. Microstructures of the aged alloys were observed by optical microscopy and scanning electron microscopy (SEM), exfoliation and intergranular corrosion behaviours were investigated according to ASTM G34-2001 and ASTM G110-1992, respectively; the mechanical properties of the aged alloys were determined followed the standard methods. The microstructures of the sample aged with the T6 temper showed the finer particle size of precipitates than that of obtained from T76x tempers. Additionally, while the T6-aged sample revealed no appearance of the Precipitate Free Zones (PFZ), the PFZ with 40–50 nm in width was observed in the alloys treated with T76x tempers. The mechanical properties of the sample aged with T76x temper were negligibly reduced comparing to that of obtained with T6 temper, however, the exfoliation and intergranular corrosion behaviours were significantly improved by using two-stage aging conditions. The mechanism in enhancement of the corrosion resistance of the alloys treated with T76x temper over T6 temper was also discussed.

The research aims at estimating the tourism and recreational values of Can Gio Mangrove Biosphere Reserve, Ho Chi Minh City, specifically, assessed the tourism potential via the willingness-to-pays of respondents (including domestic tourists and local people) for sustaining the landscape and regenerating natural resources as well as protecting the environment. The zone travel cost method was adopted in this study, to firstly plot the demand curve and then to estimate the values of recreation for visitors, eventually, come up with the total economic value of natural resources and environment of the research site. The results showed that the total recreational value of this resort is 6,542.3 billion VND while the consumer surplus values that visitors would receive from tourism activities are 1,389 billion VND. Each the tourist is willing to pay 107 thousand VND to improve the quality of tourism services, upgrading the infrastructure, sustaining the environmental quality and protecting the pristine look of the landscape.

Interpretation of wireline logging data supported to recover the sedimentary environment of block 102 of Song Hong basin. It inchided in determination of the spatial distribution of source, reservoir and cap rocks and an indispensable part in oil exploration of this area. Resulted wireline logging data showed some sedimentary environment units as the following The late Oligocene was delta environment. It was identified as forming delta plain, swamp to lacustrine. The middle Miocene had changed to shallow water marine environment, which formed the shoreface, tidal flat, lagoon and channel. The lower Miocene was aluvial environment that changed into fluvial and coastal plain.

Gas sensing is one of the most promising applications for reduced graphene oxide (rGO). High surface-to-volume ratio in conjunction with remaining reactive oxygen functional groups translates into sensitivity to molecular on the rGO surface. The response of the rGO based devices can be further improved by functionalizing its surface with metal nano-materials. In this paper, we report the ammonia (NH3) sensing behavior of rGO based sensors functionalized with nano-structured metal: silver (Ag) or platinum (Pt) or gold (Au) in air at room temperature and atmospheric pressure. The gas response is detected by the monitoring changes in electrical resistance of the rGO/metal hybrids due to NH3 gas adsorption. Compared to bare rGO, significantly improved NH3 sensitivity is observed with the addition of nano-structured metals. These materials are applied to play the small bridges role connecting many graphene islands together to improve electrical conduction of hybrids while maintaining the inherent advantage of rGO for NH3 gas sensitivity.

The synthesis of polystyrene-block-poly(iso-butyl vinyl ether) by using the combination of metallocene catalyst and atom transfer radical polymerization (ATRP) has been tried. This synthetic method takes advantages of both metallocene catalyst to form stereoregular polymer with high activity and ATRP with the controlled molecular weights and low polydispersity. The recent dinuclear half-sandwich complexes of titanium with xylene bridge, [Ti(η5-cyclopentadienyl)Cl2L]2-ortho, meta-[CH2-C6H4-CH2] (L = Cl, L = O-2,6-iPr2C6H3 ) were successfully synthesized. These catalysts were characterized by 1H NMR, 13C NMR and elemental analysis. Copolymers have been characterized by using gel permeation chromatography (GPC) and nuclear magnetic resonance (NMR). The collected copolymers have got narrow molecular weight distribution (≤1.8) and the improvement of stereoregularity (racemo dyads, r, are from 45 % to 56 %).

Natural rubber (NR) latex is considered as a “green material” because of its natural origin and a sustainable choice as well as it minimizes environmental impacts so that it has become an integral part of our daily lives. However, natural latex may contain allergenic proteins that need to be removed and this process affects the properties of vulcanized materials. In this study, an attempt has been made to incorporate cerium oxide (CeO2) into low-protein NR latex and effect of CeO2 content on the mechanical properties of the CeO2/ vulcanized rubber composite films such as tensile modulus 100% (M100), tensile modulus 300% (M300), tensile strength, tear strength was investigated. The results show that the properties of low-protein NR films were stable after 48 hrs of incubation. In particular, the mechanical properties were remarkably improved while increasing CeO2 content from 2 to 4 phr. In addition, aging resistance (AR) ability by evidence of thermal degradation and Q-sun environment test in the presence of CeO2 (4 phr) is excellent whilst AR coefficient is closest to zero. This research has provided an initial prospect of the use of rare earth oxide to produce commercially valuable products from the natural rubber resources in Vietnam.

Introduction: Breast cancer is the one of the most common types of cancer as well as the second leading cause of cancer death in women in the world. In recent studies, microRNAs (miRNAs) have been demonstrated to play a crucial role as a new potential biomarker in the association with breast cancer. Single Nucleotide Polymorphisms (SNPs) located on specific miRNA may result in breast cancer. Among the SNPs, SNP rs353291 has shown to be associated with breast cancer in individuals of Caucasian background. Furthermore, this SNP is observed in a high percentage of mutant alleles in the Vietnamese population. Thus, SNP rs353291 was selected as a candidate SNP for investigation in this study. The frequency of SNP rs353291 was evaluated by High Resolution Melting (HRM) method, which is a highly powerful method to detect variants in DNA sequence, especially for SNP genotyping. Methods: In this study, the association between this SNP and risk of breast cancer in the Vietnamese population was evaluated in 90 cases and 96 healthy controls via genotyping using an optimized HRM protocol. Result: The genotyping results revealed that SNP rs353291 is a polymorphism in the Vietnamese population. We have successfully identified frequencies of AA, AG and GG to be 40%, 42.2% and 17.8%, respectively. In particular, the calculated frequencies of allele G was 61.1% while risk allele A was 38.9%. The association between this SNP and breast cancer in Vietnam revealed that there is an obvious decreased risk of breast cancer among Vietnamese population when comparing G allele to A allele (G vs A: OR=0.92, 95% CI: 0.62-1.36, p= 0.677); the results also showed that heterozygote model had a reduced risk of breast cancer compared to dominant model (GA+GG vs AA: OR=0.94, 95% CI: 0.52-1.70, p=0.839). Conclusion: However, since the p-values were >0.05, our results only show a correlation rather than a significant association between SNP rs353291 and breast cancer risk in the Vietnamese population.

Breast cancer is one of the most common malignancies among women worldwide. GWASs have found several potential breast cancer associated SNPs in some populations. Among them, rs13281615, rs889312, rs10941679 and rs3803662 have been found to have strong relationship with breast cancer risk in different populations. Rs3803662 were statisti¬cally significantly associated with breast cancer risk in Asian population, while three others SNPs were showed to have stronger association with breast cancer in American, European and Australian than Asian. In this study, focusing on Vietnamese people only, four these SNPs were investigated to understand more about the association between these variations with breast cancer disease. An optimized genotyping method was used to genotype 600 samples including 300 controls and 300 cases. The result showed that rs13281615, rs889312, and rs10941679 were not associated with Vietnamese breast cancer patients (P>0.05). However, rs3803662 has strong association with breast cancer risk in Vietnamese population (P = 0.00122, OR = 1.454, 95%CI = 1.159-1.826). Allele A plays the role of increasing the risk of breast cancer and the genotype AA shows strongly affecting to increase breast cancer risk. Rs3803662 may involve in the list of markers using for diagnosis breast cancer in Vietnamese people in the future. A further study on larger sample size is certainly required to increase the reliability of the study. We also suggest doing more association studies for other SNPs and analyzing the haplotype to identify multiple breast cancer risk prediction markers for Vietnamese population

In this paper, Ag-Au alloy nanoparticles (NPs) were fabricated by dewetting process to enhance the broadband antireflection performance of textured silicon surfaces. The alloy NPs presented a large range of shapes and sizes, which provided an average reflectance (AR) below 4% over the spectral range of 300~1200 nm, a decrease of ~50% and ~90% as compared to the corresponding monometallic NPs and the original flat Si surfaces, respectively. The superior broadband antireflection demonstrated by the alloy NPs are attributed to the enhanced light trapping by alloy nanoparticle plasmon resonance.