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Developing host resistance is an economic and long-term approach to disease management; however, resistance reactions that differ depending on the genotypes. Potato late blight is the devastating disease caused due to Phytophthora infestans (Mont.) de Bary. In order to identify late blight resistance in potato genotypes, seven local potato cultivars (Bardiya Rato Local, Bardiya Seto Local, Cardinal, Deukhuri Rato Local, Deukhuri Seto Local, Kailali Local and Khumal Ujjowal) were evaluated in randomized complete block design (RCBD) with three replications during October 2018 to January 2019 on naturally infested soils in Deukhuri, Dang, Nepal. Results showed that significantly the highest disease incidence (99.17%), and the highest disease severity (88%) were found on Cardinal followed by Deukhuri Rato Local (64%), and Deukhuri Seto Local (60%). Potato cultivar namely Khumal Ujjowal was moderately resistant, whereas Deukhuri Rato local and Deukhuri Seto Local were susceptible to late blight disease. Significantly the highest yield (12.67 t ha -1 ) was produced by Khumal Ujjowal followed by Bardiya Rato Local (10.78 t ha -1 ) and Bardiya Seto Local (9.40 t ha -1 ). The disease incidence and Area under disease progressive curve (AUDPC) value was negatively co-related with the tuber yield. The potato cultivar Khumal Ujjowal followed by Bardiya Rato Local were found moderately resistant to late blight disease in Deukhuri conditions. This study suggests that potato cultivar Bardiya Rato Local can be grown for higher tuber production in Dang and similar topographic regions. DOI: 10.37637/ab.v3i1.464

© 2018 Elsevier B.V. Background and Objective: It can be challenging to delineate the target object in anatomical imaging when the object boundaries are difficult to discern due to the low contrast or overlapping intensity distributions from adjacent tissues. Methods: We propose a topo-graph model to address this issue. The first step is to extract a topographic representation that reflects multiple levels of topographic information in an input image. We then define two types of node connections - nesting branches (NBs) and geodesic edges (GEs). NBs connect nodes corresponding to initial topographic regions and GEs link the nodes at a detailed level. The weights for NBs are defined to measure the similarity of regional appearance, and weights for GEs are defined with geodesic and local constraints. NBs contribute to the separation of topographic regions and the GEs assist the delineation of uncertain boundaries. Final segmentation is achieved by calculating the relevance of the unlabeled nodes to the labels by the optimization of a graph-based energy function. We test our model on 47 low contrast CT studies of patients with non-small cell lung cancer (NSCLC), 10 contrast-enhanced CT liver cases and 50 breast and abdominal ultrasound images. The validation criteria are the Dice's similarity coefficient and the Hausdorff distance. Results: Student's t-test show that our model outperformed the graph models with pixel-only, pixel and regional, neighboring and radial connections (p-values

Introduction. The pathogenesis of Perthes disease is not fully understood and requires a greater understanding of the physical development, external and internal markers of connective tissue dysplasia. Objective. To analyze the deviations in physical development and connective tissue dysplasia in children with Perthes disease to determine its phenotypes. Materials and methods. We examined 52 patients and 36 children (control group) aged of 4–17 years. We estimated and compared their physical and proportional growth by using centile charts and Vervec’s index and defined external and internal manifestations of connective tissue dysplasia in major organs, systems, and topographic regions. Complete genealogical histories were taken by with examining the genealogies of 52 probands, including clinical examination of 136 first and second degree relatives. Results. Deviations in physical growth were observed in 33 patients (63.5%). The body height of 27 (51.9%) patients aged 4–17 years ranged from 1–2 lines (3–10%) and was significantly lower than that of the control group within 5 lines (p < 0.5). Six (11.6%) children had body lengths higher than the average 7th line (75–90%). Vervec’s index in 34 (65.4%) children ranged from 1.25–0.85 and represented mesomorphy, moderate brachy, or dolichomorphia. The primary pathology of external organs and systems was skeletal anomalies in 36 (69.2%) children, followed by dermal in 23 (44.2%) and organs of vision in 9 (17.3%). Among visceral disorders, the primary pathology was cardiovascular diseases in 17 (32,7%) children followed by surgical and urological pathologies in 7 (13.5%) and digestive system disorders in 5 (9.6%). Disease inheritance was sporadical in 48 (92.3%) children. Conclusion. The Perthes disease phenotype was related to the undifferentiated form of collagenopathies.

Hazardous and toxic waste are not only produced by industry, but also by household. But in fact, the household activities also produce Household Toxic and Hazardous Waste (HTHW). Considering the potential of the impact of HTHW to the reduction of environment quality, the effort of HTHW management must have been started well. One important aspect in the management strategy is to determine the characteristics and the HTHW generation. The method used to determine the characteristics HTHW refers to SNI 19-2454-2002, while the calculation HTHW generation refers to the SNI 19-3694-1994 calculated based on weight and volume. Sampling was conducted in four districts of Semarang (Pedurungan, Semarang Barat, Semarang Utara and Banyumanik). The samples used in this study were 400 families were calculated based on the proportion of Slovin Formula. Data analysis performed using Analysis of Variance (ANOVA) and Kruskal-Walis test (α = 0.05). The largest characteristic of HTHW in Semarang City is infectious (79%), further Poisonous (13%), Combustible (6%) and Corrosive (2%). While HTHW generation is 0.01 kg/person/day (5.1% MSW). Statistical test result showed there was significant difference (p-value : 0.001) between HTHW generation based on economic level, but there was no significant difference (p-value :0.442) between HTHW characteristics in Semarang city. Level of education, occupation, income level and lifestyle may become potential factor in difference characteristics and HTHW generation in Semarang city.

The availability of lake bathymetry maps is imperative for estimating lake water volumes and their variability, which is a sensitive indicator of climate. It is difficult, if not impossible, to obtain bathymetric measurements from all of the thousands of lakes across the globe due to costly labor and/or harsh topographic regions. In this study, we develop a new digital lake bathymetry model (DLBM) using the step-wise water recession method (WRM) to generate 3-dimensional lake bathymetric maps based on the digital elevation model (DEM) alone, with two assumptions: (1) typically, the lake&rsquo, s bathymetry is formed and shaped by geological processes similar to those that shaped the surrounding landmasses, and (2) the agent rate of water (the thickness of the sedimentary deposit proportional to the lake water depth) is uniform. Lake Ontario and Lake Namco are used as examples to demonstrate the development, calibration, and refinement of the model. Compared to some other methods, the estimated 3D bathymetric maps using the proposed DLBM could overcome the discontinuity problem to adopt the complex topography of lake boundaries. This study provides a mathematically robust yet cost-effective approach for estimating lake volumes and their changes in regions lacking field measurements of bathymetry, for example, the remote Tibetan Plateau, which contains thousands of lakes.

The Parsnip River area in British Columbia (BC), Canada, provides important habitat for grizzly bears (Ursus arctos). This area contains 2 adjacent topographic regions: (1) a relatively pristine portion of the Hart Ranges of the Canadian Rocky Mountains, and (2) a plateau on which timber harvests have occurred. Increasing human modification of both landscapes may affect the quality of grizzly bear habitat. Therefore, we examined denning behavior and den-site selection of grizzly bears in this area based on data from 61 grizzly bears radiocollared between 1997 and 2002 (34 plateau, 27 mountain bears). Adult females residing in the mountainous landscape arrived earlier to their denning areas (14 Oct versus 26 Oct), entered dens earlier (23 Oct versus 9 Nov), and emerged later (11 May versus 24 Apr) than plateau females, spending on average 36 days longer in their dens (200 days versus 164 days). Dens used in consecutive years by mountain females tended to be closer to one another (x = 2.4 km) than those of plateau females (x = 5.1 km). Dens in the mountains were excavations into sloping ground (74%), or natural caves (26%), using rocks as the primary stabilizing structure (47%). Resource selection functions (RSF) revealed that mountain grizzly bears selected dens in alpine habitats at mid-to-upper elevations. Plateau bears mainly excavated dens under the base of trees (90%), where roots stabilized material (80%). These dens primarily were located in older-aged forest stands ranging from 45–99 years (40%) or >100 years (50%); RSFs further revealed that grizzly bears on the plateau selected stands with tall trees. Plateau dens also were located away from roads, possibly because of less disturbance and because older trees were farther from roads.

[1] Topologically, water bodies are the first-level topographic regions that get flooded, and as the flood level gets higher, adjacent water bodies merge. The looplike network that forms along all these merging points represents zones of influence of each water body. These two topologically interdependent phenomena follow the universal scaling laws similar to certain other environmental and biological phenomena. Despite morphological variations, water bodies and their influence zones of varied sizes and shapes have different sets of scaling exponents, thereby determining that they belong to different universality classes.

The aim of the current study was to investigate the gender effecton minor physical anomalies (MPA) in schizophrenic patients and normal controls. Seventy-six schizophrenic patients (43 males and 33 females) and 82 normal control subjects (42 males and 40 females) were examined for MPA using a modified version of the Waldrop Physical Anomaly Scale. Men tended to be more stigmatized with MPA than women both in normal subjects and in schizophrenics (with this difference slightly expanding in schizophrenics). In both genders schizophrenic patients were significantly more likely to have MPA than normal controls, but the difference tended to be more pronounced in males. There was a tendency towards sex-related predilection for the increase of MPA in schizophrenics in terms of individual anomalies and topographic regions affected. Among schizophrenics, genders showed a somewhat opposite topography of MPA stigmatization, with relatively more pronounced peripheral dysmorphy in males and craniofacial dysmorphy in females. These data suggest greater vulnerability of the male fetus to endogenous or exogenous factors and different susceptibilities to developmental adversities in male and female schizophrenics. This finding is in accord with the increasing evidence that sex differences in the epidemiology of schizophrenia may be broader and more fundamental than previously thought.

In the face of the current debate on ‘cadaverless’ teaching of anatomy (Guttmann et al. 2004; McLachlan et al. 2004), the publication of the 13th edition of this classic ‘cook book’ of human dissection is a vindication of the irreplaceably tried and true method of gaining anatomical knowledge. With a new author assuming the mantle of this eponymous ‘Dissector’ with a 60-year publication record, the realities of the reduced curriculum time allocated for anatomical dissection are taken into account. The book is highly integrated with its complementary Grant's Atlas of Anatomy, 12th edition (although incorrectly indicating the 11th edition, page 4), and with three other popular anatomical atlases. The dissection instructions are organized into seven ‘stand alone’ topographic regions that allow for interchangeable approaches to the order of dissection. Each regional description follows a set pattern of surface anatomy, then osteology, with a preview of ‘before you dissect …’, followed by explicit instructions in a numbered sequence. A review, ‘after you dissect …’ emphasizes the significant facts and includes specific references (page and plate numbers) to four anatomical atlases. This theme is in keeping with the best tradition of reiteration and reinforcement as a pedagogical protocol that makes this text an admirable tutor. Colour-coded boxes distinguish the xanthochroic ‘Dissection Instructions’ from the cerulean ‘Clinical Correlations’, interspersed with clear, appropriately coloured drawings of the anatomical structures and the best approach to their dissection. The terminology used is in accordance with the Terminologia Anatomica, reducing potential confusion of nomenclature. The glossy paper on which this book is printed will serve to some extent to repel the ravages of dissection-room exposure. The spiralbound version will more likely survive the inevitable expansive opening for which the text is designed. In summary, a highly recommended tool for dissection.