67 results on '"Simion, F"'
Search Results
2. Lo sviluppo della mente umana. Dalle teorie classiche ai nuovi orientamenti
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MACCHI CASSIA, V, Valenza, E, Simion, F, MACCHI CASSIA, VIOLA MARINA, Simion F., MACCHI CASSIA, V, Valenza, E, Simion, F, MACCHI CASSIA, VIOLA MARINA, and Simion F.
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Il volume offre un panorama aggiornato dei modelli teorici che la psicologia ha elaborato per spiegare le cause e i meccanismi che determinano lo sviluppo della mente umana. Dopo aver affrontato nella prima parte le teorie classiche, le autrici passano in rassegna, nella seconda parte, i modelli più recenti relativi allo sviluppo cognitivo, sottolineandone gli aspetti interdisciplinari. È così illustrato con chiarezza il fondamentale ruolo che questo filone di ricerca svolge nell’indagine sull’architettura e sul funzionamento della mente umana.
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- 2012
3. Face detection in complex visual displays: An eye tracking study with 3- and 6-month-old infants and adults
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Di Giorgio, E, Turati, C, Altoé, G, Simion, F, Simion, F., TURATI, CHIARA, Di Giorgio, E, Turati, C, Altoé, G, Simion, F, Simion, F., and TURATI, CHIARA
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The ability to detect and prefer a face when embedded in complex visual displays was investigated in 3- and 6-month-old infants, as well as in adults, through a modified version of the visual search paradigm and the recording of eye movements. Participants (N= 43) were shown 32 visual displays that comprised a target face among 3 or 5 heterogeneous objects as distractors. Results demonstrated that faces captured and maintained adults' and 6-month-olds' attention, but not 3-month-olds' attention. Overall, the current study contributes to knowledge of the capacity of social stimuli to attract and maintain visual attention over other complex objects in young infants as well as in adults. © 2012 Elsevier Inc.
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- 2012
4. Holistic face processing in newborns, 3-month-old infants and adults: Evidence from the composite effect
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Turati, C, di Giorgio, E, Bardi, L, Simion, F, TURATI, CHIARA, Simion, F., Turati, C, di Giorgio, E, Bardi, L, Simion, F, TURATI, CHIARA, and Simion, F.
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Holistic face processing was investigated in newborns, 3-month-old infants, and adults through a modified version of the composite face paradigm and the recording of eye movements. After familiarization to the top portion of a face, participants (N = 70) were shown 2 aligned or misaligned faces, 1 of which comprised the familiar top part. In the aligned condition, no visual preference was found at any group age. In the misaligned condition, 3-month-olds preferred the face stimulus with the familiar top part, adults preferred the face stimulus with the novel one, and newborns did not manifest any visual preference. Results revealed that both infants' and adults' eye movements may be affected by holistic face information and demonstrated holistic face processing in 3-month-olds. © 2010 The Authors. Child Development © 2010 Society for Research in Child Development, Inc.
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- 2010
5. The visual search of an illusory figure: A comparison between 6-month-old infants and adults
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Bulf, H, Valenza, E, Simion, F, BULF, HERMANN SERGIO, Simion, F., Bulf, H, Valenza, E, Simion, F, BULF, HERMANN SERGIO, and Simion, F.
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The aim of the present study was to investigate how perceptual binding and selective attention operate during infants' and adults' visual search of an illusory figure. An eye-tracker system was used to test adults and infants in two conditions: illusory and non-illusory (real). In the illusory condition, a Kanizsa triangle was embedded among distractor pacmen which did not generate illusory contours. In the non-illusory condition, a real triangle was included in the same pacmen's display. The results showed that adults detected both the Kanizsa and the real figure automatically and without focal attention (experiment 1). In contrast, 6-month-old infants showed a pop-out effect only for the real figure (experiment 2). The failure of the illusory figure to trigger infants' attention was not due to infants' inability to perceive the illusory figure per se, as infants preferred the illusory figure over a non-illusory control stimulus in a classical preferential-looking task (experiment 3). Overall, these findings indicate that the illusory Kanizsa triangle triggers visual attention in adults, but not in infants, supporting evidence that at 6 months of age the binding processes involved in the perception of a Kanizsa figure do not operate in an adult-like manner.
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- 2009
6. I meccanismi che mediano la preferenza visiva per il volto a tre mesi di vita e negli adulti
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Leo, I, Turati, C, Valenza, E, Simion, F, Simion, F., TURATI, CHIARA, Leo, I, Turati, C, Valenza, E, Simion, F, Simion, F., and TURATI, CHIARA
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- 2009
7. Newborns face recognition is based on spatial frequencies below 0.5 cycles per degree
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de Heering, A, Turati, C, Rossion, B, Bulf, H, Goffaux, V, Simion, F, Simion, F., TURATI, CHIARA, BULF, HERMANN SERGIO, de Heering, A, Turati, C, Rossion, B, Bulf, H, Goffaux, V, Simion, F, Simion, F., TURATI, CHIARA, and BULF, HERMANN SERGIO
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A critical question in Cognitive Science concerns how knowledge of speciWc domains emerges during development. Here we examined how limitations of the visual system during the Wrst days of life may shape subsequent development of face processing abilities. By manipulating the bands of spatial frequencies of face images, we investigated what is the nature of the visual information that newborn infants rely on to perform face recognition. Newborns were able to extract from a face the visual information lying from 0 to 1 cpd (Experiment 1), but only a narrower 0–0.5 cpd spatial frequency range was successful to accomplish face recognition (Experiment 2). These results provide the Wrst empirical support of a low spatial frequency advantage in individual face recognition at birth and suggest that early in life low-level, non-speciWc perceptual constraints aVect the development of the face processing system
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- 2008
8. Holistic face processing can be independent of gaze behavior: Evidence from the composite face effect
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de Heering, A, Rossion, B, Turati, C, Simion, F, Simion, F., TURATI, CHIARA, de Heering, A, Rossion, B, Turati, C, Simion, F, Simion, F., and TURATI, CHIARA
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People tend to perceive identical top halves (i.e. above the nose) of two face stimuli as being different when they are aligned with distinct bottom halves. This face composite illusion has been demonstrated almost 20 years ago (Young et al., 1987), and is generally considered as the most compelling evidence that facial features are integrated into a holistic representation. Here, we recorded eye movements during the face composite effect, i.e. when the top and the bottom parts of a composite face stimulus are integrated into a single holistic face representation. The behavioral results showed a strong face composite effect when subjects maintained fixation to the top part of the face stimulus. Fixation sites and eye movements were virtually identical when the top and bottom parts were aligned (composite illusion) or misaligned (no illusion), indicating that holistic face processing can be independent of gaze behavior. These findings reinforce the view that holistic representations of individual faces can be extracted early on from low spatial frequency analysis, independently of overt attention.
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- 2008
9. Newborns’ face recognition over changes in viewpoint
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Turati, C, Bulf, H, Simion, F, TURATI, CHIARA, BULF, HERMANN SERGIO, Simion, F., Turati, C, Bulf, H, Simion, F, TURATI, CHIARA, BULF, HERMANN SERGIO, and Simion, F.
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The study investigated the origins of the ability to recognize faces despite rotations in depth. Four experiments are reported that tested, using the habituation technique, whether 1-to-3-day-old infants are able to recognize the invariant aspects of a face over changes in viewpoint. Newborns failed to recognize facial perceptual invariances between profile and full-face poses (Experiment 1), and profile and 3/4 poses (Experiment 3). Conversely, newborns recognized the identity of a face through full-face and 3/4 poses (Experiment 2). This result cannot be explained as a consequence of newborns’ inability to discriminate between the full-face and 3/4 points of view (Experiment 4). Overall, evidence was provided that newborns are able to derive a representation of an unfamiliar face that is resilient to a certain degree of rotation in depth, from full-face to 3/4 and vice versa.
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- 2008
10. Three-month-olds' visual preference for faces and its underlying visual processing mechanisms
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Turati, C, Valenza, E, Leo, I, Simion, F, TURATI, CHIARA, Valenza E., Leo I., Simion F., Turati, C, Valenza, E, Leo, I, Simion, F, TURATI, CHIARA, Valenza E., Leo I., and Simion F.
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This study was aimed at investigating the face preference phenomenon and its underlying mechanisms at 3 months of age. Using an eye-tracker apparatus, Experiment 1 demonstrated that 3-month-olds prefer natural face images to unnatural ones, replicating and extending previous evidence obtained with schematic facelike stimuli. Experiments 2 and 3 showed that the general mechanisms that induce face preference in newborns could not explain the same phenomenon at 3 months of age, when infants are attracted by perceptual cues more specific to faces. This suggests that signs of a process of cognitive specialization are already present in 3-month-olds' visual behavior toward faces. © 2004 Elsevier Inc. All rights reserved.
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- 2005
11. Lo sviluppo cognitivo: dalle teorie classiche ai nuovi orientamenti
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MACCHI CASSIA, V, Valenza, E, Simion, F, MACCHI CASSIA, VIOLA MARINA, Simion, F., MACCHI CASSIA, V, Valenza, E, Simion, F, MACCHI CASSIA, VIOLA MARINA, and Simion, F.
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- 2004
12. Can a nonspecific bias toward top-heavy patterns explain newborns' face preference?
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MACCHI CASSIA, V, Turati, C, Simion, F, MACCHI CASSIA, VIOLA MARINA, TURATI, CHIARA, Simion, F., MACCHI CASSIA, V, Turati, C, Simion, F, MACCHI CASSIA, VIOLA MARINA, TURATI, CHIARA, and Simion, F.
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This study examined newborns' face preference using images of natural and scrambled faces in which the location of the inner features was distorted. The results demonstrate that newborns' face preference is not confined to schematic configurations, but can be obtained also with veridical faces. Moreover, this phenomenon is not produced by a specific bias toward the face geometry, but derives from a domain-general bias toward configurations with more elements in the upper than in the lower half (i.e., top-heavy patterns). These results suggest that it may be unnecessary to assume the existence of a prewired tendency to orient toward the face geometry, and support the idea that faces do not possess a special status in newborns' visual world.
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- 2004
13. Differenze individuali nell’esplorazione visuo-manipolatoria e strategie di elaborazione dell’informazione
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MACCHI CASSIA, V, Simion, F, MACCHI CASSIA, VIOLA MARINA, Simion, F., MACCHI CASSIA, V, Simion, F, MACCHI CASSIA, VIOLA MARINA, and Simion, F.
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Molte ricerche dimostrano che le differenze individuali nella durata della fissazione visiva nella prima infanzia sono riconducibili alla tendenza da parte dei soggetti a selezionare le informazioni di livello globale o locale contenute nello stimolo. Nella presente ricerca, la tecnica dell’object-examining (Ruff et al., 1992) è stata utilizzata allo scopo di verificare se, anche nel caso della modalità visuo-manipolatoria, esista una relazione tra la durata del comportamento esplorativo e la natura, locale o globale, dell'informazione estratta dall'oggetto. I dati emersi da uno studio pilota confermano la validità dell'examining come misura dei processi attentivi implicati nella selezione dell'informazione durante l'esplorazione visuo-manipolatoria degli oggetti. I risultati della ricerca presentata dimostrano che le differenze individuali nella durata dell’attività esplorativa riflettono la tendenza da parte del soggetto a selezionare informazioni di livello differente: i bambini che producono episodi di examining di breve durata selezionano principalmente le proprietà globali degli oggetti, mentre i bambini che esplorano gli oggetti per lunghi periodi selezionano soprattutto gli aspetti di livello locale. In linea con la letteratura, i risultati suggeriscono l'esistenza di forti analogie tra le misure della fissazione visiva e le misure dell'examining, intese entrambe come indici dei processi di elaborazione dell'informazione messi in atto dal bambino, ed estendono la convergenza tra le due misure al dominio delle differenze individuali.
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- 2003
14. Individual differences in object-examining duration: Do they reflect the use of different encoding strategies?
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MACCHI CASSIA, V, Simion, F, MACCHI CASSIA, VIOLA MARINA, Simion, F., MACCHI CASSIA, V, Simion, F, MACCHI CASSIA, VIOLA MARINA, and Simion, F.
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Much evidence has shown that individual differences in the duration of visual fixation in infancy are related to processing of wholistic versus featural properties of the stimuli. In the present study, an object-examining technique was used with 8-month-old infants to test the hypothesis that infants who display differential attention durations to visuo-manually presented stimuli will vary in their processing of wholistic vs featural aspects of the stimuli. The results confirmed the hypothesis, indicating that, after being familiarized with an object comprised of both global and local properties, long examiners attended more to an object comprised of new-local rather than new-global aspects, whereas short examiners attended more to the new-global rather than the new-local object. These findings provide support to the contention of the existence of close similarities between visual fixation and object-examining measures as indexes of infant information processing, extending the convergences between the two measures to the domain of individual differences.
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- 2002
15. Interferenza asimmetrica tra l'informazione locale e globale alla nascita
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MACCHI CASSIA, V, Simion, F, MACCHI CASSIA, VIOLA MARINA, Simion, F., MACCHI CASSIA, V, Simion, F, MACCHI CASSIA, VIOLA MARINA, and Simion, F.
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Two experiments were carried out to demonstrate the existence of a global precedence effect in newborns, as it was found in adults and in 3-4 month old infants. The results demonstrated that, when the two levels of visual information are equally discriminable, newborns showed an asymmetric interference between the two levels. This finding provides evidence for a processing dominance of global over local information.
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- 2001
16. L'organizzazione percettiva alla nascita: modalità di elaborazione analitica e globale
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MACCHI CASSIA, V, Farroni, T, Valenza, E, Turati, C, Simion, F, MACCHI CASSIA, VIOLA MARINA, TURATI, CHIARA, Simion, F., MACCHI CASSIA, V, Farroni, T, Valenza, E, Turati, C, Simion, F, MACCHI CASSIA, VIOLA MARINA, TURATI, CHIARA, and Simion, F.
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Sono stati condotti tre esperimenti al fine di dimostrare che il neonato è in grado di imporre un'organizzazione strutturale all'informazione visiva contenuta nello stimolo sulla base del principio gestaltico della vicinanza. I risultati emersi dall'Esperimento 1, nel quale è stata utilizzata la tecnica dell'abituazione, dimostrano che le abilità visive del neonato sono sufficientemente sviluppate da consentire la discriminazione dei singoli elementi che compongono la configurazione. I risultati dell'Esperimento 2, nel quale è stata utilizzata la tecnica della preferenza visiva, mostrano che i neonati generalizzano la preferenza spontanea per bande orientate in senso orizzontale piuttosto che verticale (Esperimento 2a) anche a scacchiere formate da singole componenti raggruppabili in colonne verticali e righe orizzontali (Esperimento 2b). Ciò dimostra che i neonati sono in grado raggruppare tali componenti, organizzandole in unità percettive di ordine superiore.
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- 2001
17. The cradle of causal reasoning: newborns' preference for physical causality, Developmental Science
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Mascalzoni, E, Regolin, L, Vallortigara, G, and Simion F.
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- 2013
18. Nachweis und Bestimmung des Chroms
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Muller, J. A., Reinhardt, C., Fischbach, C., Siebenschub, A., Stanek, V., Randall, N. M., Bogoluboff, K., Wdowiszewski, H., Garrat, F., Demorest, D. J., Cain, J. R., Walters, H. E., Daniels, F. C. T., Field, A. J., Terni, A., Malaguti, P., Evans, B. S., Winkler, L. W., Barnebey, O. L., Kelley, G. L., Wiley, J. A., Little, E., Costa, J., Gröger, M., Ward, H. O., Slawik, P., Hild, W., and Simion, F.
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- 1923
- Full Text
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19. Schmelzpunktsbestimmungen
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Lynn, G., Hosking, J. R., Short, W. F., Kerckow, F., Anschütz, R., Speter, M., Winkler, L. W., Wick, G., Barchfeld, G., Niethammer, Anneliese, Borgström, L. H., Matthaes, W., Herbst, H., Kisser, J., Wendriner, M., and Simion, F.
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- 1931
- Full Text
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20. La suzione non nutritiva: uno strumento per lo studio delle competenze neonatali
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MACCHI CASSIA, V, Simion, F, MACCHI CASSIA, VIOLA MARINA, Simion, F., MACCHI CASSIA, V, Simion, F, MACCHI CASSIA, VIOLA MARINA, and Simion, F.
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The aim of the present study is to review the existing literature on Nonnutritive Sucking (NNS ) as a tool for investigating neonatal capabilities. Three research areas where NNS was utilized with newborn and infants are considered: regulation of states, visual scanning, attentional processes. In the light of new reported data concerning the relation between NNS and processing of visual and acoustic information at birth, a comprehensive interpretative framework is presented to explain the apparently contradictory results emerging from the three outlined research fields.
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- 1997
21. LCA Modeling of Waste Management Scenarios
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Christensen, Thomas Højlund, Simion, F., Tonini, Davide, Møller, Jacob, Christensen, Thomas Højlund, Simion, F., Tonini, Davide, and Møller, Jacob
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Lifecycle assessment (LCA) modeling provides a quantitative statement about resource issues and environmental issues in waste management useful in evaluating alternative management systems and in mapping where major loads and savings take place within existing systems. Chapter 3.1 describes the concepts behind LCA modeling and Chapter 3.2 gives an overview of existing models and shows examples of their application. A recent comprehensive review of publicly available LCA studies (WRAP, 2006) concluded that, on a material basis, LCA modeling in general confirms the validity of the waste hierarchy and shows that recycling is superior to incineration with energy recovery, which again is better than landfilling. Cleary (2010) reviewed 20 waste management scenarios assessed in 11 studies published in the period 2002–2008 and concluded that, due to lack of transparency regarding boundary conditions and exchange with the energy systems, a comparison of results was hampered on a system level. In addition, differences in waste composition may affect the LCA results. This chapter provides results of LCA modeling of 40 waste management scenarios handling the same municipal waste (MSW) and using different combinations of waste recycling, biological treatment, incineration, mechanical–biological treatment and landfilling. The purpose is to compare waste management on a system level and to indentify the steps and treatments within the system contributing the most to the environmental performance of waste management systems. The study focuses on Europe in terms of waste composition and exchange with the energy system. The waste management systems modeled are described with respect to waste composition, waste management technologies, mass flows and energy exchange in the systems. Results are first presented with respect to Global Warming contributions (kg of CO2-eq./t of waste). These data are identical to those presented in Christensen et al. (2009). Finally also results for other
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- 2011
22. Congruency as a non-specific perceptual property contributing to newborns’ face preference
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Macchi Cassia, V, Valenza, E, Simion, F, Leo, I, Macchi Cassia, V, Valenza, E, Simion, F, and Leo, I
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Past research has shown that top-heaviness is a perceptual property that plays a crucial role in triggering newborns’ preference toward faces. The present study examined the contribution of a second configural property, congruency, to newborns’ face preference. Experiments 1 and 2 demonstrated that, when embedded in non-facelike stimuli, congruency induces a preference of the same strength of that induced by facedness. Experiments 3 and 4 demonstrated that the attentional biases toward facedness and congruency produce a cumulative effect on newborns’ visual preferences according to an additive model. These findings were extended by those of Experiment 5, showing that the additive model holds true when congruency is added to top-heaviness in non-facelike stimuli displaying more elements in the upper portion.
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- 2008
23. A predisposition for biological motion in the newborn baby
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Simion, F, Regolin, L, Bulf, H, BULF, HERMANN SERGIO, Simion, F, Regolin, L, Bulf, H, and BULF, HERMANN SERGIO
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An inborn predisposition to attend to biological motion has long been theorized, but had so far been demonstrated only in one animal species (the domestic chicken). In particular, no preference for biological motion was reported for human infants of <3 months of age. We tested 2-day-old babies’ discrimination after familiarization and their spontaneous preferences for biological vs. nonbiological point-light animations. Newborns were shown to be able to discriminate between two different patterns of motion (Exp. 1) and, when first exposed to them, selectively preferred to look at the biological motion display (Exp. 2). This preference was also orientation-dependent: newborns looked longer at upright displays than upside-down displays (Exp. 3). These data support the hypothesis that detection of biological motion is an intrinsic capacity of the visual system, which is presumably part of an evolutionarily ancient and nonspecies-specific system predisposing animals to preferentially attend to other animals.
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- 2008
24. How face specialization emerges in the first months of life
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Von Hofsten, C, Rosander, K, Simion, F, Leo, I, Turati, C, Valenza, E, TURATI, CHIARA, Valenza, E., Von Hofsten, C, Rosander, K, Simion, F, Leo, I, Turati, C, Valenza, E, TURATI, CHIARA, and Valenza, E.
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The present chapter deals with the topic of the ontogeny and development of face processing in the first months of life and is organized into two sections concerning face detection and face recognition. The first section focuses on the mechanisms underlying infants' visual preference for faces. Evidence is reviewed supporting the contention that newborns' face preferences is due to a set of non-specific constraints that stem from the general characteristics of the human visuo-perceptual system, rather than to a representational bias for faces. It is shown that infants' response to faces becomes more and more tuned to the face category over the first 3 months of life, revealing a gradual progressive specialization of the face-processing system. The second section sought to determine the properties of face recognition at birth. In particular, a series of experiments are presented to examine whether the inner facial part is processed and encoded when newborns recognize a face, and what kind of information - featural or configural - newborns' face recognition rely on. Overall, results are consistent with the existence of general constraints present at birth that tune the system to become specialized for faces later during development.
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- 2007
25. Il riconoscimento del volto alla nascita
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Leo, I, Turati, C, MACCHI CASSIA, V, Simion, F, Dalla Barba, B, Dalla Barba, B., TURATI, CHIARA, MACCHI CASSIA, VIOLA MARINA, Leo, I, Turati, C, MACCHI CASSIA, V, Simion, F, Dalla Barba, B, Dalla Barba, B., TURATI, CHIARA, and MACCHI CASSIA, VIOLA MARINA
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The present study investigated, using the habituation technique, what perceptual cues are used by newborns in the process of recognition of a stranger's face. Evidence showed that newborns are able to discriminate and recognize a face when all the facial features are visible (exp. 1), and when only the inner (exp. 2) or the other features are present (exp. 3).
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- 2007
26. Newborns' face recognition: role of inner and outer facial features
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Turati, C, MACCHI CASSIA, V, Simion, F, Leo, I, TURATI, CHIARA, MACCHI CASSIA, VIOLA MARINA, Leo, I., Turati, C, MACCHI CASSIA, V, Simion, F, Leo, I, TURATI, CHIARA, MACCHI CASSIA, VIOLA MARINA, and Leo, I.
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Existing data indicate that newborns are able to recognize individual faces, but little is known about what perceptual cues drive this ability. The current study showed that either the inner or outer features of the face can act as sufficient cues for newborns' face recognition (Exp.1), but the outer part of the face enjoys an advantage over the inner part (Exp. 2). Inversion of the face stimuli disrupted recognition when only the inner portion of the face was shown, but not when the whole face was fully visible or only the outer features were presented (Exp. 3). The results enhance our picture of what information newborns actually process and encode when they discriminate, learn and recognize faces.
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- 2006
27. The emergence of cognitive specialization in infancy: The case of face preference
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Johnson, M, Munakata, M, Simion, F, Turati, C, Valenza, E, Leo, I, Leo, I., TURATI, CHIARA, Johnson, M, Munakata, M, Simion, F, Turati, C, Valenza, E, Leo, I, Leo, I., and TURATI, CHIARA
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- 2006
28. Non-specific perceptual biases at the origins of face processing
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Pascalis, O, Slater, A, Simion, F, MACCHI CASSIA, V, Turati, C, Valenza, E, Valenza, E., MACCHI CASSIA, VIOLA MARINA, TURATI, CHIARA, Pascalis, O, Slater, A, Simion, F, MACCHI CASSIA, V, Turati, C, Valenza, E, Valenza, E., MACCHI CASSIA, VIOLA MARINA, and TURATI, CHIARA
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- 2003
29. Newborns' preference for up-down asymmetrical configurations
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Simion, F, Valenza, E, MACCHI CASSIA, V, Turati, C, Umiltà, C, MACCHI CASSIA, VIOLA MARINA, TURATI, CHIARA, Umiltà, C., Simion, F, Valenza, E, MACCHI CASSIA, V, Turati, C, Umiltà, C, MACCHI CASSIA, VIOLA MARINA, TURATI, CHIARA, and Umiltà, C.
- Abstract
The present study was aimed at investigating whether, because of a differential sensitivity between the upper and the lower visual fields, in a visual preference task newborns would orient more frequently and look longer at patterns with a great number of high-contrast areas in the upper or lower visual field Newborns were presented with three pairs of geometrical stimuli, each composed of a pattern with a greater number of elements in the upper part or a pattern with more elements in the lower part, The results showed a reliable preference for the stimuli that had more elements in the upper than in the lower part. The evidence obtained suggests the possibility that, at birth, the visibility of a stimulus depends not only on its sensory properties, but also on its structural characteristics
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- 2002
30. L’organizzazione della percezione visiva alla nascita
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Di Stefano, G, Vianello, R, Simion, F, MACCHI CASSIA, V, Turati, C, MACCHI CASSIA, VIOLA MARINA, TURATI, CHIARA, Di Stefano, G, Vianello, R, Simion, F, MACCHI CASSIA, V, Turati, C, MACCHI CASSIA, VIOLA MARINA, and TURATI, CHIARA
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- 2002
31. Newborns' local processing in schematic facelike configurations
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Simion, F, Farroni, T, MACCHI CASSIA, V, Turati, C, Dalla Barba, B, MACCHI CASSIA, VIOLA MARINA, TURATI, CHIARA, Dalla Barba, B., Simion, F, Farroni, T, MACCHI CASSIA, V, Turati, C, Dalla Barba, B, MACCHI CASSIA, VIOLA MARINA, TURATI, CHIARA, and Dalla Barba, B.
- Abstract
The goal of the study was to provide a direct comparison of newborns' ability to process and store, over a 2min delay, the shape of the internal local elements of schematic facelike and non-facelike patterns. Two experiments were carried out using a visual habituation technique with an infant control procedure. The results demonstrate that newborns discriminated between two schematic facelike and non-facelike configurations that differed exclusively for the shape of the internal local elements (Expt 1), and they maintained this discriminative ability even when recognition was tested after a 2min retention interval (Expt 2). The results are consistent with the existence of a general pattern learning mechanism that mediates newborns' ability to acquire information about any pattern, including faces (de Schonen Mancini, 1995; de Schonen, Mancini, Liegeois 1998; Johnson, 1997)
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- 2002
32. Dominance of global visual properties at birth
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Macchi Cassia, V, Simion, F, Milani, I, Umilta, C, Macchi Cassia, VM, Umilta, C., Macchi Cassia, V, Simion, F, Milani, I, Umilta, C, Macchi Cassia, VM, and Umilta, C.
- Abstract
Six experiments are reported that were aimed at demonstrating the presence in newborns of a perceptual dominance of global over local visual information in hierarchical patterns, similar to that observed in adults (D. Navon, 1977, 198 1). The first four experiments showed that, even though both levels of visual information were detectable by the newborn (Experiments 1A and 1B), global cues enjoyed some advantage over local cues (Experiments 2 and 3). Experiments 4A and 4B demonstrated that the global bias was strictly dependent on the low spatial frequency content of the stimuli and vanished after selective removal of low spatial frequencies. The results are interpreted as suggesting parallels between newborns' visual processing and processing later in development
- Published
- 2002
33. Face preference at birth: the role of an orienting mechanism
- Author
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Macchi Cassia, V, Simion, F, Umiltà, C, Macchi Cassia, V, Simion, F, and Umiltà, C
- Abstract
It has been proposed that newborns' preferential orienting to faces is solely controlled by a subcortically mediated orienting mechanism (i.e., Conspec). In contrast preferential-looking tasks show that face preference at birth manifests itself also with measures that index fixation duration. It is possible, however, that orienting and fixation duration are confounded and only orienting matters. The present study used a revised version of the preferential-looking technique, in which the same stimulus (i.e., a facelike or a nonfacelike pattern) was simultaneously presented to both sides of the visual field. Results showed that longer total fixation times on the facelike stimuli resulted from the sum of a greater number of brief fixations, rather than from the sum of a small number of long fixations. These findings support the hypothesis that, for facelike patterns, the duration of infant's fixation on the stimulus is determined by the nature of the pattern that impinges on the periphery of the visual field, more than by the nature of the pattern that is being looked at.
- Published
- 2001
34. The origins of face perception: specific vs non-specific mechanisms
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Simion, F, MACCHI CASSIA, V, Turati, C, Valenza, E, Valenza, E., MACCHI CASSIA, VIOLA MARINA, TURATI, CHIARA, Simion, F, MACCHI CASSIA, V, Turati, C, Valenza, E, Valenza, E., MACCHI CASSIA, VIOLA MARINA, and TURATI, CHIARA
- Abstract
Many studies demonstrated that newborns prefer upright faces over upside-down faces. Based on this evidence, some have suggested that faces represent a special class of stimuli for newborns and there is a qualitative difference between the processes involved in perception of facelike and non-facelike patterns (i.e., structural hypothesis). Others suggest that there is no reason to suppose that faces are different from other patterns, because faces, like any other classes of visual stimuli, are subject to filtering by the properties of the visual system (i.e., sensory hypothesis). The core question that will be adressed in the present paper is whether, to manifest itself, face preference requires the unique structure of the face, represented by the relative spatial location of its internal features, or rather some more general properties that other stimuli may also possess. Evidence will be presented supporting the idea that newborns do not respond to facelike stimuli by "facedness" but, rather, by some general structural characteristics that best satisfy the constraints of the immature visual system.
- Published
- 2001
35. Face Preference at Birth
- Author
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Valenza, E, Simion, F, Macchi Cassia, V, Umiltà, C, Macchi Cassia, VM, Umiltà, C., Valenza, E, Simion, F, Macchi Cassia, V, Umiltà, C, Macchi Cassia, VM, and Umiltà, C.
- Abstract
Four experiments are reported that were aimed at elucidating some of the controversial issues concerning the preference for facelike patterns in newborns. The experiments were devised to contrast the original and the revised versions of the sensory hypothesis and the structural hypothesis as accounts of face preference in newborns, Experiments 1A and 1B supported the structural hypothesis by showing a visual preference for the stimulus for which components were located in the correct arrangement for a human face, Experiment 2 supported the sensory hypothesis by showing a visual preference for stimuli that were designed to have the optimal spatial frequency components for the newborn visual system. Experiment 3 showed that babies directed attention to a facelike pattern also when it was presented simultaneously with a nonfacelike stimulus with optimal spatial frequency for the newborn visual system
- Published
- 1996
36. Strumenti per la valutazione delle competenze neonatali
- Author
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Donnarumma D'Alessio, M, Ricci Bitti, P, Villone Bettocchi, G, Simion, F, MACCHI CASSIA, V, Valenza, E, Dalla Barba, B, Dalla Barba, B., MACCHI CASSIA, VIOLA MARINA, Donnarumma D'Alessio, M, Ricci Bitti, P, Villone Bettocchi, G, Simion, F, MACCHI CASSIA, V, Valenza, E, Dalla Barba, B, Dalla Barba, B., and MACCHI CASSIA, VIOLA MARINA
- Published
- 1995
37. Two distinct mechanisms for taurocholate uptake in subcellular fractions from rat liver.
- Author
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Simion, F A, Fleischer, B, and Fleischer, S
- Abstract
As part of the enterohepatic circulation, hepatocytes take up bile acids from the intestines via the hepatic portal blood using a sodium-dependent carrier mechanism and resecrete the bile acids into the bile. In order to assess whether intracellular organelles are involved in the transcellular secretion of bile acids, we measured directly the ability of purified subcellular fractions of rat liver to take up taurocholate using a Millipore filtration assay. Two distinct uptake mechanisms can be discerned, one localized in the plasma membranes and the other in the Golgi and smooth microsomal fractions. Plasma membranes prepared by the method of Fleischer and Kervina (Fleischer, S., and Kervina, M. (1974) Methods Enzymol. 31, 6) take up taurocholate in a saturable manner with an apparent Vmax of 2.4 nmol min-1 mg protein-1 and a Km of 190 microM at 37 degrees C. After preincubation of the membranes with K+ ions, a sodium gradient (100 mM outside) stimulates the uptake rate by 90% with the observed Km unchanged. The stimulation is inhibited by phalloidin but not by bromosulfophthalein. Bile canalicular plasma membranes made according to Kramer et al. (Kramer, W., Bickel, U., Buscher, H. P., Gerok, W., and Kurz, G. (1982) Eur. J. Biochem. 129, 13-24) do not take up taurocholate. The transport by Golgi vesicles and smooth microsomes differs from that in the plasma membrane fraction in that it is not stimulated by a sodium gradient, has a Vmax of 12 nmol min-1 mg protein-1 and a Km of 440 microM at 37 degrees C, and is inhibited by bromosulfophthalein but not by phalloidin. Taurocholate uptake into smooth microsomes is abolished by filipin, an antibiotic that complexes with cholesterol to disrupt the membrane. This suggests that taurocholate uptake occurs into a nonendoplasmic reticulum subfraction since endoplasmic reticulum membranes contain negligible amounts of cholesterol. Little uptake was observed using rough microsomes or mitochondria. A model of transhepatic transport compatible with our observations is that taurocholate uptake into the cytoplasm occurs via the plasma membranes on the sinusoidal side of the hepatocyte; taurocholate is then taken up into smooth vesicles and the Golgi complex and is secreted into the bile by exocytosis as the vesicles fuse with the canalicular plasma membranes.
- Published
- 1984
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38. Teichoic acid and lipid metabolism during sporulation of Bacillus megaterium KM
- Author
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Johnstone, K, Simion, F A, and Ellar, D J
- Abstract
The biochemistry of teichoic acid and lipid metabolism has been studied during sporulation of Bacillus megaterium KM. Measurements of cell-wall and membrane teichoic acid have shown that net synthesis of these polymers ceases at the onset of sporulation. Pulse-labelling studies show that the period of asymmetric septation and forespore engulfment is marked by an initiation of turnover of membrane teichoic acid but not of wall teichoic acid. This is reflected in the presence of inner-membrane teichoic acid and the virtual absence of wall teichoic acid in dormant spores. The total amount of lipid phosphorus in the sporulating cell increases by 70% as a result of asymmetric septation and subsequent engulfment of the forespore. The phosphorus requirement for this synthesis is derived from a pool formed during exponential growth, which is not exchangeable with extracellular Pi during sporulation. These results suggest that during sporulation a proportion of the glycerol 3-phosphate produced by preferential degradation of membrane teichoic acid formed during exponential growth is used for phospholipid synthesis during sporulation.
- Published
- 1982
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39. Can a Nonspecific Bias Toward Top-Heavy Patterns Explain Newborns' Face Preference?
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Francesca Simion, Chiara Turati, Viola Macchi Cassia, MACCHI CASSIA, V, Turati, C, and Simion, F
- Subjects
Visual perception ,top-heavy ,05 social sciences ,Infant, Newborn ,050109 social psychology ,Fixation, Ocular ,Choice Behavior ,Lower half ,innate bias ,050105 experimental psychology ,Preference ,face preference ,Cognition ,newborn ,Face ,Face (geometry) ,Fixation (visual) ,Visual Perception ,Humans ,0501 psychology and cognitive sciences ,Psychology ,Social psychology ,General Psychology - Abstract
This study examined newborns' face preference using images of natural and scrambled faces in which the location of the inner features was distorted. The results demonstrate that newborns' face preference is not confined to schematic configurations, but can be obtained also with veridical faces. Moreover, this phenomenon is not produced by a specific bias toward the face geometry, but derives from a domain-general bias toward configurations with more elements in the upper than in the lower half (i.e., top-heavy patterns). These results suggest that it may be unnecessary to assume the existence of a prewired tendency to orient toward the face geometry, and support the idea that faces do not possess a special status in newborns' visual world.
- Published
- 2004
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40. A predisposition for biological motion in the newborn baby
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Hermann Bulf, Francesca Simion, Lucia Regolin, Simion, F, Regolin, L, and Bulf, H
- Subjects
Male ,medicine.medical_specialty ,Visual perception ,Time Factors ,Light ,Concept Formation ,Motion Perception ,Audiology ,Biology ,Motion (physics) ,Discrimination Learning ,Motion ,Discrimination, Psychological ,M-PSI/04 - PSICOLOGIA DELLO SVILUPPO E PSICOLOGIA DELL'EDUCAZIONE ,Orientation ,medicine ,Humans ,Attention ,Motion perception ,Discrimination learning ,Animal species ,Newborns ,Multidisciplinary ,Infant, Newborn ,Biological Sciences ,Biological motion ,Preference ,Biological motion perception ,Pattern Recognition, Visual ,Visual Perception ,Female - Abstract
An inborn predisposition to attend to biological motion has long been theorized, but had so far been demonstrated only in one animal species (the domestic chicken). In particular, no preference for biological motion was reported for human infants of
- Published
- 2008
41. Newborns' face recognition: role of inner and outer facial features
- Author
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Francesca Simion, Chiara Turati, Viola Macchi Cassia, Irene Leo, Turati, C, MACCHI CASSIA, V, Simion, F, and Leo, I
- Subjects
Male ,Visual perception ,media_common.quotation_subject ,Speech recognition ,Facial recognition system ,Education ,Perception ,Developmental and Educational Psychology ,Humans ,media_common ,newborns, face recognition, inner-outer features ,Facial expression ,Communication ,business.industry ,Infant, Newborn ,Recognition, Psychology ,Infant newborn ,Facial Expression ,Recien nacido ,Visual discrimination ,Face (geometry) ,Face ,Pediatrics, Perinatology and Child Health ,Female ,Psychology ,business - Abstract
Existing data indicate that newborns are able to recognize individual faces, but little is known about what perceptual cues drive this ability. The current study showed that either the inner or outer features of the face can act as sufficient cues for newborns' face recognition (Experiment 1), but the outer part of the face enjoys an advantage over the inner part (Experiment 2). Inversion of the face stimuli disrupted recognition when only the inner portion of the face was shown, but not when the whole face was fully visible or only the outer features were presented (Experiment 3). The results enhance our picture of what information newborns actually process and encode when they discriminate, learn, and recognize faces.
- Published
- 2006
42. Survivorship and complications of cementless compared to cemented posterior-stabilized total knee arthroplasties: A systematic review and meta-analysis.
- Author
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Chahidi E, Martinov S, Simion F, Mercier C, Sabot L, Kyriakydis T, Callewier A, and Hernigou J
- Abstract
Purpose: Controversy exists on the best fixation for total knee arthroplasty (TKA). Non-cemented fixation has been theorized to improve patient outcomes and longevity of implantation but no study has focused on comparison between cemented or cementless posterior-stabilized implants despite being the most commonly or second most frequently utilized implant in most total knee replacement registries., Methods: Inclusion criteria with observational and interventional papers, and review articles that focused on patients with cementless and cemented PS TKAs were used to analyze outcomes such as implant survivorship, complication, or revision rates. Using a combination of keywords, a systematic search was performed on Medline (PubMed), Embase, and Cochrane Library for Meta-Analysis., Results: When using the specified criteria, only 8 studies were selected for full-text analysis and meta-analysis after eliminating screening duplicates, titles, and abstracts without full-text access. These eight studies contain 1652 patients, 693 in the non-cemented Group, and 959 in the cemented total knee prosthesis Group. The meta-analysis revealed the advantage of cementless fixation over cemented fixation in implant survivorship, with 0.6% and 2.6% of aseptic loosening in each Group. The cumulative survival at 12 years was 97.4% for the cementless Group and 89.2% for the cemented Group. The subgroup with a stem showed a positive outcome for cementless fixation over cemented fixation regarding implant survivorship. No differences between the cemented and cementless TKAs were observed in patient-reported outcomes, revision rates, or radiolucent line development., Conclusion: We observed comparable rates for cemented and cementless posterior-stabilized TKAs over a medium-term follow-up period., (© The Authors, published by EDP Sciences, 2024.)
- Published
- 2024
- Full Text
- View/download PDF
43. Abnormal visual attention to simple social stimuli in 4-month-old infants at high risk for Autism.
- Author
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Di Giorgio E, Rosa-Salva O, Frasnelli E, Calcagnì A, Lunghi M, Scattoni ML, Simion F, and Vallortigara G
- Subjects
- Age Factors, Autism Spectrum Disorder etiology, Humans, Infant, Infant, Newborn, Learning, Risk, Attention physiology, Autism Spectrum Disorder physiopathology, Autism Spectrum Disorder psychology, Fixation, Ocular physiology
- Abstract
Despite an increasing interest in detecting early signs of Autism Spectrum Disorders (ASD), the pathogenesis of the social impairments characterizing ASD is still largely unknown. Atypical visual attention to social stimuli is a potential early marker of the social and communicative deficits of ASD. Some authors hypothesized that such impairments are present from birth, leading to a decline in the subsequent typical functioning of the learning-mechanisms. Others suggested that these early deficits emerge during the transition from subcortically to cortically mediated mechanisms, happening around 2-3 months of age. The present study aimed to provide additional evidence on the origin of the early visual attention disturbance that seems to characterize infants at high risk (HR) for ASD. Four visual preference tasks were used to investigate social attention in 4-month-old HR, compared to low-risk (LR) infants of the same age. Visual attention differences between HR and LR infants emerged only for stimuli depicting a direct eye-gaze, compared to an adverted eye-gaze. Specifically, HR infants showed a significant visual preference for the direct eye-gaze stimulus compared to LR infants, which may indicate a delayed development of the visual preferences normally observed at birth in typically developing infants. No other differences were found between groups. Results are discussed in the light of the hypotheses on the origins of early social visual attention impairments in infants at risk for ASD., (© 2021. The Author(s).)
- Published
- 2021
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44. Newborns' sensitivity to speed changes as a building block for animacy perception.
- Author
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Di Giorgio E, Lunghi M, Vallortigara G, and Simion F
- Subjects
- Cues, Humans, Attention physiology, Infant, Newborn psychology, Motion, Motion Perception physiology, Photic Stimulation
- Abstract
The human visual system can discriminate between animate beings vs. inanimate objects on the basis of some kinematic cues, such as starting from rest and speed changes by self-propulsion. The ontogenetic origin of such capability is still under debate. Here we investigate for the first time whether newborns manifest an attentional bias toward objects that abruptly change their speed along a trajectory as contrasted with objects that move at a constant speed. To this end, we systematically manipulated the motion speed of two objects. An object that moves with a constant speed was contrasted with an object that suddenly increases (Experiment 1) or with one that suddenly decreases its speed (Experiment 2). When presented with a single speed change, newborns did not show any visual preference. However, newborns preferred an object that abruptly increases and then decreases its speed (Experiment 3), but they did not show any visual preference for the reverse sequence pattern (Experiment 4). Overall, results are discussed in line with the hypothesis of the existence of attentional biases in newborns that trigger their attention towards some visual cues of motion that characterized animate perception in adults.
- Published
- 2021
- Full Text
- View/download PDF
45. Individually distinctive features facilitate numerical discrimination of sets of objects in domestic chicks.
- Author
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Rugani R, Loconsole M, Simion F, and Regolin L
- Subjects
- Animals, Cognition physiology, Face physiology, Female, Visual Perception physiology, Chickens physiology, Discrimination Learning physiology
- Abstract
Day-old domestic chicks approach the larger of two groups of identical objects, but in a 3 vs 4 comparison, their performance is random. Here we investigated whether adding individually distinctive features to each object would facilitate such discrimination. Chicks reared with 7 objects were presented with the operation 1 + 1 + 1 vs 1 + 1 + 1 + 1. When objects were all identical, chicks performed randomly, as expected (Experiment 1). In the remaining experiments, objects differed from one another due to additional features. Chicks succeeded when those features were differently oriented segments (Experiment 2) but failed when the features were arranged to depict individually different face-like displays (Experiment 3). Discrimination was restored if the face-like stimuli were presented upside-down, disrupting global processing (Experiment 4). Our results support the claim that numerical discrimination in 3 vs 4 comparison benefits from the presence of distinctive features that enhance object individuation due to individual processing. Interestingly, when the distinctive features are arranged into upright face-like displays, the process is susceptible to global over local interference due to configural processing. This study was aimed at assessing whether individual object processing affects numerical discrimination. We hypothesise that in humans similar strategies aimed at improving performance at the non-symbolic level may have positive effects on symbolic mathematical abilities.
- Published
- 2020
- Full Text
- View/download PDF
46. A comparison between preterm and full-term infants' preference for faces.
- Author
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Pereira SA, Pereira Junior A, Costa MF, Monteiro MV, Almeida VA, Fonseca Filho GG, Arrais N, and Simion F
- Subjects
- Child Development, Choice Behavior, Cross-Sectional Studies, Female, Fixation, Ocular, Gestational Age, Humans, Infant, Newborn, Infant, Premature, Male, Facial Recognition
- Abstract
Objective: Visual preference for faces at birth is the product of a multimodal sensory experience experienced by the fetus even during the gestational period. The ability to recognize faces allows an ecologically advantageous interaction with the social environment. However, perinatal events such as premature birth, may adversely affect the adequate development of this capacity. In this study, we evaluated the preference for facial stimuli in preterm infants within the first few hours after birth., Methods: This is a cross-sectional observational study of 59 newborns, 28 preterm and 31 full-term infants. The babies were assessed in the first hours of life, with two white boards in the shape of a head and neck: one with the drawing of a face similar to the human face (natural face), and one with the drawing of misaligned eyes, mouth and nose (distorted face). After the newborn fixated the eyes on the presented stimulus, it was slowly moved along the visual field. The recognition of the stimulus was considered present when the baby had eye or head movements toward the stimulus., Results: The preterm infants, in addition to showing a lower occurrence of orientation movements for both stimuli, on average (1.8±1.1 to natural faces and 2.0±1.2 for distorted ones) also showed no preference for any of them (p=0.35). Full-term newborns showed a different behavior, in which they showed a preference for natural faces (p=0.002) and a higher number of orientations for the stimulus, for both natural (3.2±0.8) and distorted faces (2.5±0.9)., Conclusion: Preterm newborns recognize facial stimuli and disclose no preference for natural faces, different from full-term newborns., (Copyright © 2016 Sociedade Brasileira de Pediatria. Published by Elsevier Editora Ltda. All rights reserved.)
- Published
- 2017
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47. Corrigendum: Difference in Visual Social Predispositions Between Newborns at Low- and High-risk for Autism.
- Author
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Di Giorgio E, Frasnelli E, Rosa Salva O, Scattoni ML, Puopolo M, Tosoni D, Simion F, and Vallortigara G
- Published
- 2016
- Full Text
- View/download PDF
48. Difference in Visual Social Predispositions Between Newborns at Low- and High-risk for Autism.
- Author
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Di Giorgio E, Frasnelli E, Rosa Salva O, Scattoni ML, Puopolo M, Tosoni D, Simion F, and Vallortigara G
- Subjects
- Child, Preschool, Female, Humans, Infant, Infant, Newborn, Interpersonal Relations, Male, Social Behavior, Social Perception, Attention, Autism Spectrum Disorder diagnosis, Autism Spectrum Disorder psychology
- Abstract
Some key behavioural traits of Autism Spectrum Disorders (ASD) have been hypothesized to be due to impairments in the early activation of subcortical orienting mechanisms, which in typical development bias newborns to orient to relevant social visual stimuli. A challenge to testing this hypothesis is that autism is usually not diagnosed until a child is at least 3 years old. Here, we circumvented this difficulty by studying for the very first time, the predispositions to pay attention to social stimuli in newborns with a high familial risk of autism. Results showed that visual preferences to social stimuli strikingly differed between high-risk and low-risk newborns. Significant predictors for high-risk newborns were obtained and an accurate biomarker was identified. The results revealed early behavioural characteristics of newborns with familial risk for ASD, allowing for a prospective approach to the emergence of autism in early infancy.
- Published
- 2016
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- View/download PDF
49. Face perception and processing in early infancy: inborn predispositions and developmental changes.
- Author
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Simion F and Giorgio ED
- Abstract
From birth it is critical for our survival to identify social agents and conspecifics. Among others stimuli, faces provide the required information. The present paper will review the mechanisms subserving face detection and face recognition, respectively, over development. In addition, the emergence of the functional and neural specialization for face processing as an experience-dependent process will be documented. Overall, the present work highlights the importance of both inborn predispositions and the exposure to certain experiences, shortly after birth, to drive the system to become functionally specialized to process faces in the first months of life.
- Published
- 2015
- Full Text
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50. Dynamics, deterministic nature and correlations of outdoor (222)Rn and (220)Rn progeny concentrations measured at Bacău, Romania.
- Author
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Cuculeanu V, Simion F, Simion E, and Geicu A
- Subjects
- Background Radiation, Romania, Seasons, Time Factors, Weather, Radiation Monitoring, Radon chemistry
- Abstract
The long-term variation, nature and correlations of outdoor (222)Rn and (220)Rn progeny concentrations measured during the period 1994-2009 were investigated. The time series of data were obtained within the framework of the monitoring program performed by the Environmental Radioactivity Monitoring Station (ERMS) Bacău, a component part of the National Environmental Radioactivity Survey Network (NERSN), coordinated by National Environmental Protection Agency (NEPA). The measuring method is based on the total beta measurements of atmospheric aerosol filters, using a low background total beta counter and ((90)Sr/Y) reference standard. Analysis of the time series of progeny concentrations in the low atmosphere makes evident different patterns of variation of these concentrations: diurnal, seasonal and annual. A possible relationship of progeny concentration increase with global warming is emphasized. In order to find the dominant frequency of the physical processes determining progeny concentration variability the power spectrum has been used. The deterministic nature of the time series of concentrations has been studied making use of the autocorrelation function and stationarity of the original data and of their phase randomized time series. Also, the correlations with meteorological parameters have been investigated using Pearson's correlation coefficient with corresponding level of significance., (2011 Elsevier Ltd. All rights reserved.)
- Published
- 2011
- Full Text
- View/download PDF
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