182 results on '"Scott, Kenneth L"'
Search Results
2. PI4KIIIβ is a therapeutic target in chromosome 1q–amplified lung adenocarcinoma
3. Rational combination therapy with PARP and MEK inhibitors capitalizes on therapeutic liabilities in RAS mutant cancers
4. PIK3CA variants selectively initiate brain hyperactivity during gliomagenesis
5. Bacteria-to-Human Protein Networks Reveal Origins of Endogenous DNA Damage
6. Literature-based automated discovery of tumor suppressor p53 phosphorylation and inhibition by NEK2
7. Systematic Functional Annotation of Somatic Mutations in Cancer
8. A Pan-Cancer Proteogenomic Atlas of PI3K/AKT/mTOR Pathway Alterations
9. The RNA-binding protein AKAP8 suppresses tumor metastasis by antagonizing EMT-associated alternative splicing
10. The epithelial-to-mesenchymal transition activator ZEB1 initiates a prometastatic competing endogenous RNA network
11. Combinatorial inhibition of PTPN12-regulated receptors leads to a broadly effective therapeutic strategy in triple-negative breast cancer
12. Functionally Assessing Candidate Drivers Advances Precision Cancer Medicine
13. Analyzing Somatic Genome Rearrangements in Human Cancers by Using Whole-Exome Sequencing
14. The Genomic Landscape and Clinical Relevance of A-to-I RNA Editing in Human Cancers
15. The GABA Transaminase, ABAT, Is Essential for Mitochondrial Nucleoside Metabolism
16. In vivo functional characterization of EGFR variants identifies novel drivers of glioblastoma
17. Neomorphic PDGFRA extracellular domain driver mutations are resistant to PDGFRA targeted therapies
18. RNA editing derived epitopes function as cancer antigens to elicit immune responses
19. A functional genomic screen in vivo identifies CEACAM5 as a clinically relevant driver of breast cancer metastasis
20. Mutations in FBXL4 Cause Mitochondrial Encephalopathy and a Disorder of Mitochondrial DNA Maintenance
21. Lysyl hydroxylase 2 induces a collagen cross-link switch in tumor stroma
22. mTORC1-Dependent and -Independent Regulation of Stem Cell Renewal, Differentiation, and Mobilization
23. Proinvasion Metastasis Drivers in Early-Stage Melanoma Are Oncogenes
24. A functional genomic approach to actionable gene fusions for precision oncology
25. In vivo functional characterization of EGFR variants identifies novel drivers of glioblastoma.
26. SMAD4-dependent barrier constrains prostate cancer growth and metastatic progression
27. GOLPH3 modulates mTOR signalling and rapamycin sensitivity in cancer
28. POT1 Regulates Proliferation and Confers Sexual Dimorphism in Glioma
29. Differential expression of MAGEA6 toggles autophagy to promote pancreatic cancer progression
30. TMEM106B drives lung cancer metastasis by inducing TFEB-dependent lysosome synthesis and secretion of cathepsins
31. In vivo screening identifies GATAD2B as a metastasis driver in KRAS-driven lung cancer
32. Cancer driver mutation prediction through Bayesian integration of multi-omic data
33. A-to-I RNA Editing Contributes to Proteomic Diversity in Cancer
34. Daam2 driven degradation of VHL promotes gliomagenesis
35. HER2 Reactivation through Acquisition of the HER2 L755S Mutation as a Mechanism of Acquired Resistance to HER2-targeted Therapy in HER2+ Breast Cancer
36. Engineering and Functional Characterization of Fusion Genes Identifies Novel Oncogenic Drivers of Cancer
37. Ba/F3 transformation assays
38. Systematic characterization of A-to-I RNA editing hotspots in microRNAs across human cancers
39. Circulating Tumor Cells from 4D Model Have Less ITGB4 Expression
40. Abstract B25: A novel in vivo gain-of-function screen for metastasis drivers in non-small cell lung cancers
41. Functional annotation of rare gene aberration drivers of pancreatic cancer
42. Identification of Variant-Specific Functions of PIK3CA by Rapid Phenotyping of Rare Mutations
43. Abstract 955: High-throughput functional screening for metastasis drivers of lung cancer
44. High-Throughput Functional Validation of Progression Drivers in Lung Adenocarcinoma
45. Daam2 driven degradation of VHL promotes gliomagenesis.
46. Intronic miR-211 Assumes the Tumor Suppressive Function of Its Host Gene in Melanoma
47. Polygenic in vivovalidation of cancer mutations using transposons
48. Third-party beneficiary analysis in federal housing law: in search of uniformity.
49. High-Throughput Functional Validation of Progression Drivers in Lung Adenocarcinoma
50. Abstract C199: Coordinate phosphorylation of multiple residues on single AKT1 and AKT2 molecules.
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