Search

Your search keyword '"Schutter, Rianne"' showing total 8 results
Start Over Author "Schutter, Rianne" Search Limiters Full Text
8 results on '"Schutter, Rianne"'

2. Optimizing utilization and quality assessment of deceased donor kidneys

Author

Schutter, Rianne and Schutter, Rianne

Abstract

When patients have end-stage organ failure, organ transplantation is often the best (and sometimes even the only) option. The shortage of donor organs remains a persistent global problem. As deceased donor organs are scarce, it is of great importance that available organs are used optimally. This thesis sheds light on the donation process and kidney utilization of deceased donor kidneys in the Netherlands, clinical decision-making in kidney offers for transplantation, long-term outcomes of kidney preservation methods, and finally it discusses the role of MRI in pre-transplant kidney quality assessment, and in identifying possible complications after transplantation. We concluded that 24% of deceased donor kidneys, that seemed medically suitable in the first place, were not transplanted. Furthermore, we objectified that kidney acceptance is very prone to subjective judgments by doctors, with little consensus on which suboptimal donor kidney should be transplanted or discarded. Finally, we developed a method to visualize intrarenal regional physiological and metabolic processes of a procured kidney on a pump, by several MRI techniques. To conclude, we provide suggestions to improve kidney utilization of deceased donors covering the entire donation cascade, starting during a potential donor’s treatment at the intensive care unit, via a complex sequence of events until eventual transplantation.

Published
2023

3. Considerable Variability Among Transplant Nephrologists in Judging Deceased Donor Kidney Offers

Author

MS Nefrologie, Circulatory Health, Schutter, Rianne, Sanders, Jan Stephan F., Ramspek, Chava L., Crop, Meindert J., Bemelman, Frederike J., Christiaans, Maarten H.L., Hilbrands, Luuk B., de Vries, Aiko P.J., van de Wetering, Jacqueline, van Zuilen, Arjan D., van Diepen, Merel, Leuvenink, Henri G.D., Dekker, Friedo W., Moers, Cyril, MS Nefrologie, Circulatory Health, Schutter, Rianne, Sanders, Jan Stephan F., Ramspek, Chava L., Crop, Meindert J., Bemelman, Frederike J., Christiaans, Maarten H.L., Hilbrands, Luuk B., de Vries, Aiko P.J., van de Wetering, Jacqueline, van Zuilen, Arjan D., van Diepen, Merel, Leuvenink, Henri G.D., Dekker, Friedo W., and Moers, Cyril

Published
2023

5. Kidney utilization in the Netherlands – do we optimally use our donor organs?

Author

Schutter, Rianne, Vrijlandt, Willemijn A L, Weima, Gelske M, Pol, Robert A, Sanders, Jan-Stephan F, Crop, Meindert J, Leuvenink, Henri G D, and Moers, Cyril

Subjects
*KIDNEYS, *ORGAN donors, *ACUTE kidney failure
Abstract

Background To ensure optimal utilization of deceased donor kidneys, it is important to understand the precise reasons why kidneys are discarded. In this study we aimed to obtain a comprehensive overview of kidney utilization and discard during the entire donation process in the Netherlands. Methods In this retrospective cohort study we analysed kidney utilization of 3856 kidneys in the Netherlands between 1 January 2015 and 31 December 2020. For every kidney that was not transplanted, we determined the moment of and reason for discard through a unique case-by-case assessment. Results Kidney discard according to the traditional definition (procured but not transplanted) was 7.8%. However, when kidneys that seemed medically suitable at the beginning of the donation process were also included, many more potential donor kidneys were lost and the total non-utilization was 24.4%. Subjectively presumed impaired organ quality was responsible for 34.2% of all discarded kidneys. Two-thirds of kidneys discarded due to acute kidney injury (AKI) had only AKI stage 1 or 2. Conclusion The classical definition of organ discard underestimates the non-utilization of deceased donor kidneys. Strategies to improve kidney utilization could be a revision of the maximum allowed agonal time in donation after circulatory death, careful consideration in reporting and accepting kidneys from donors with AKI and a prospectively filled registry of detailed organ discard reasons, including the 'silent' non-utilization before procurement. [ABSTRACT FROM AUTHOR]

Published
2023
Full Text
View/download PDF

8. Magnetic resonance imaging assessment of renal flow distribution patterns during ex vivo normothermic machine perfusion in porcine and human kidneys

Author

Schutter, Rianne, primary, Lantinga, Veerle A., additional, Hamelink, Tim L., additional, Pool, Merel B. F., additional, Varsseveld, Otis C., additional, Potze, Jan Hendrik, additional, Hillebrands, Jan‐Luuk, additional, van den Heuvel, Marius C., additional, Dierckx, Rudi A. J. O., additional, Leuvenink, Henri G. D., additional, Moers, Cyril, additional, and Borra, Ronald J. H., additional

Published
2021
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results