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Your search keyword '"Schmidt, Jan-Hendrik"' showing total 7 results
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7 results on '"Schmidt, Jan-Hendrik"'

1. Addressing the spin-valley flavors in moir'e mini-bands of MoS2

Author

Sharma, Chithra H., Prada, Marta, Schmidt, Jan-Hendrik, D'iaz-Palacio, Isabel Gonz'alez, Stauber, Tobias, Taniguchi, Takashi, Watanabe, Kenji, Tiemann, Lars, and Blick, Robert H.

Subjects
Condensed Matter - Mesoscale and Nanoscale Physics
Abstract

The physics of moir'e superlattices and the resulting formation of mini-bands in van der Waals materials have opened up an exciting new field in condensed matter physics. These systems exhibit a rich phase diagram of novel physical phenomena and exotic correlated phases that emerge in the low-dispersing bands. Transition metal dichalcogenides, in particular, molybdenum disulfide (MoS2), are potential candidates to extend the studies on moir'e electronics beyond graphene. Our transport spectroscopy measurements and analysis reveal a correlation-driven phase transition and the emergence of discrete mini-bands in MoS2 moir'e superlattices that remained elusive so far. We resolve these mini-bands arising from quantum mechanical tunneling through Schottky barriers between the MoS2 and its metallic leads. Energy scales deduced from a first approach exhibit an astounding agreement with our experimental observations. The behavior under thermal activation suggests a Lifshitz phase transition at low temperatures that is driven by a complete spin-valley symmetry breaking. These intriguing observations bring out the potential of twisted MoS2 to explore correlated electron states and associated physics.

Published
2023
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5. Implications of subsidiary cropping and tillage system on economics and production risk

Author

Blumenstein, Benjamin, Finkh, Maria Renate, Schmidt, Jan Hendrik, Westaway, Sally, Brandsæter, Lars Olav, Möller, Detlev, and Rahmann, Gerold

Subjects
Crop combinations and interactions, Farm nutrient management, Crop husbandry, Farming Systems, Farm economics
Abstract

Subsidiary cropping and mulch systems as well as conservation tillage may induce multiple positive agro-ecological effects, increasing resilience and yield stability of cash cropping in organic farming systems. As this may also implicitly affect production economics and risk potential, the paper at hand evaluates two year crop-rotations from empiric field data, considering costs and revenues of production as well as yield effects based on stochastic risk simulation. Absolute profitability as well as risk potential substantially varies between cropping systems and locations and does not necessarily display a definite preference of conventional/reduced tillage or subsidiary cropping systems. However, a temporal expansion of the period under observation considering long-term effects of soil fertility enhancing management practices may illustrate their risk-reducing potential as well as the necessity to handle them as long-term investments with instant expenses and subsequent economic returns.

Published
2017

6. Implications of subsidiary cropping and tillage system on economics and production risk

Author

Rahmann, Gerold, Blumenstein, Benjamin, Finkh, Maria Renate, Schmidt, Jan Hendrik, Westaway, Sally, Brandsæter, Lars Olav, Möller, Detlev, Rahmann, Gerold, Blumenstein, Benjamin, Finkh, Maria Renate, Schmidt, Jan Hendrik, Westaway, Sally, Brandsæter, Lars Olav, and Möller, Detlev

Abstract

Subsidiary cropping and mulch systems as well as conservation tillage may induce multiple positive agro-ecological effects, increasing resilience and yield stability of cash cropping in organic farming systems. As this may also implicitly affect production economics and risk potential, the paper at hand evaluates two year crop-rotations from empiric field data, considering costs and revenues of production as well as yield effects based on stochastic risk simulation. Absolute profitability as well as risk potential substantially varies between cropping systems and locations and does not necessarily display a definite preference of conventional/reduced tillage or subsidiary cropping systems. However, a temporal expansion of the period under observation considering long-term effects of soil fertility enhancing management practices may illustrate their risk-reducing potential as well as the necessity to handle them as long-term investments with instant expenses and subsequent economic returns.

Published
2017

7. Targeting postsynaptic glutamate receptor scaffolding proteins PSD-95 and PICK1 for obesity treatment.

Author

Fadahunsi, Nicole, Petersen, Jonas, Metz, Sophia, Jakobsen, Alexander, Vad Mathiesen, Cecilie, Buch-Rasmussen, Alberte Silke, Kurgan, Nigel, Larsen, Jeppe Kjærgaard, Andersen, Rita C., Topilko, Thomas, Svendsen, Charlotte, Apuschkin, Mia, Skovbjerg, Grethe, Schmidt, Jan Hendrik, Houser, Grace, Jager, Sara Elgaard, Bach, Anders, Deshmukh, Atul S., Kilpeläinen, Tuomas O., and Strømgaard, Kristian

Subjects
*SCAFFOLD proteins, *GLUTAMATE receptors, *PROTEIN receptors, *REGULATION of body weight, *GENOME-wide association studies, *FAT
Abstract

Human genome-wide association studies (GWAS) suggest a functional role for central glutamate receptor signaling and plasticity in body weight regulation. Here, we use UK Biobank GWAS summary statistics of body mass index (BMI) and body fat percentage (BF%) to identify genes encoding proteins known to interact with postsynaptic a-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) and N-methyl-d-aspartate (NMDA) receptors. Loci in/near discs large homolog 4 (DLG4) and protein interacting with C kinase 1 (PICK1) reached genome-wide significance (P < 5 × 10-8) for BF% and/or BMI. To further evaluate the functional role of postsynaptic density protein-95 (PSD-95; gene name: DLG4) and PICK1 in energy homeostasis, we used dimeric PSD-95/disc large/ZO-1 (PDZ) domain-targeting peptides of PSD-95 and PICK1 to demonstrate that pharmacological inhibition of PSD-95 and PICK1 induces prolonged weight-lowering effects in obese mice. Collectively, these data demonstrate that the glutamate receptor scaffolding proteins, PICK1 and PSD-95, are genetically linked to obesity and that pharmacological targeting of their PDZ domains represents a promising therapeutic avenue for sustained weight loss. [ABSTRACT FROM AUTHOR]

Published
2024
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