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1. Quality known. GlobeWQ final report

Author

Schmidt, Christian, Jomaa, Seifeddine, Bärlund, Ilona, Büttner, Olaf, Borchardt, Dietrich, Kumar, Rohini, Batool, Masooma, Schenk, K., Heege, T., Bauer, P., Bernert, H., Flörke, M., Rivera, J., Dürr, H., Kynast, E., Paulsen, H., Rothstein, U., Blitza, H., Schmidt, Christian, Jomaa, Seifeddine, Bärlund, Ilona, Büttner, Olaf, Borchardt, Dietrich, Kumar, Rohini, Batool, Masooma, Schenk, K., Heege, T., Bauer, P., Bernert, H., Flörke, M., Rivera, J., Dürr, H., Kynast, E., Paulsen, H., Rothstein, U., and Blitza, H.

Abstract

Water quality is an essential component of the Sustainable Development Goals (SDGs), specifically highlighted in SDG 6, which focuses on „Ensuring availability and sustainable management of water and sanitation for all.“ While the title may suggest a primary emphasis on drinking water and sanitation, SDG 6 encompasses a much broader scope, including the preservation of aquatic ecosystems and the maintenance of ambient water quality.Maintaining and restoring good ambient water quality is essential for the integrity of aquatic ecosystems on the one hand, while on the other hand aquatic ecosystems provide services to society such as natural purification of water and the storage of freshwater in the landscape. But water quality hazards are present all over the world: Increasing pollution of freshwater as a result of rapid economic growth and urbanization in developing countries, and sustained, chronic pollution including long-term legacies in developed countries.In 2019 a report entitled „Quality unknown“ by the Worldbank concluded that the water quality status is largely invisible and unknown because of the lack of information on water quality.In the 2021 progress update on SDG 6.3.2, water quality could not be assessed for about three billion people due the lack of water quality data. It is obvious that there is a need to improve water quality information.The GlobeWQ project was designed to address the global challenge of improving water quality information. It was conducted from October 1st, 2019 to December 31st, 2022 funded by the German Federal Ministry of Education and Research (BMBF).At a global scale, GlobeWQ has further developed and applied the WorldQual water quality model, providing information on concentration of fecal coliform bacteria, biological oxygen demand and total dissolved solids for rivers worldwide. A data-driven approach was applied to estimate global nitrate concentrations.In addition to global information products, GlobeWQ has also developed

Published
2023

5. Patient-Reported Outcome Measurement Compared with Professional Judgment of Cosmetic Results after Breast-Conserving Therapy

Author

Brands-Appeldoorn, Angelique T. P. M., primary, Maaskant-Braat, A. J. G., additional, Zwaans, W. A. R., additional, Dieleman, J. P., additional, Schenk, K. E., additional, Broekhuysen, C. L., additional, Weerdenburg, H., additional, Daniels, R., additional, Tjan-Heijnen, V. C. G., additional, and Roumen, R. M. H., additional

Published
2018
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7. Global lakes sentinel services: Evaluation of Chl-A trends in deep clear lakes

Author

Ouwehand, L, Cazzaniga, I, Giardino, C, Bresciani, M, Poser, K, Peters, S, Hommersom, A, Schenk, K, Heege, T, Philipson, P, Ruescas, A, Böttcher, M, Stelzer, K, CAZZANIGA, ILARIA, Stelzer, K., Ouwehand, L, Cazzaniga, I, Giardino, C, Bresciani, M, Poser, K, Peters, S, Hommersom, A, Schenk, K, Heege, T, Philipson, P, Ruescas, A, Böttcher, M, Stelzer, K, CAZZANIGA, ILARIA, and Stelzer, K.

Abstract

The aim of this study is the analysis of trend in the trophic level evolution in clear deep lakes which, being characterised by good quality state, are important socio-economic resources for their regions. The selected lakes are situated in Europe (Garda, Maggiore, Constance and Vättern), North America (Michigan) and Africa (Malawi and Tanganyika) and cover a range of eco-regions (continental, perialpine, boreal, rift valley) distributed globally. To evaluate trophic level tendency we mainly focused on chlorophyll-A concentrations (chl-a) which is a direct proxy of trophic status. The chl-A concentrations were obtained from 5216 cloud-free MERIS imagery from 2002 to 2012. The 'GLaSS RoIStats tool' available within the GLaSS project was used to extract chl-A in a number of region of interests (ROI) located in pelagic waters as well as some few other stations depending on lakes morphology. For producing the time-series trend, these extracted data were analysed with the Seasonal Kendall test. The results overall show almost stable conditions with a slight increase in concentration for lakes Maggiore, Constance, and the Green Bay of Lake Michigan; a slight decrease for lakes Garda and Tanganyika and absolutely stable conditions for lakes Vättern and Malawi. The results presented in this work show the great capability of MERIS to perform trend tests analysis on trophic status with focus on chl-A concentration. Being chl-A also a key parameter in water quality monitoring plans, this study also supports the managing practices implemented worldwide for using the water of the lakes.

Published
2016

9. Seventh Annual Meeting of the European Association for the Study of Diabetes: Southampton, England, September 15–17, 1971

Author

Knussman, R., Toeller, M., Kopf, A., Tchobroutsky, G., Eschwege, E., Dauchy, F., Korec, R., Koschinsky, Th., Gries, F. A., Herberg, L., Krug, E., Mialhe, P., Marliss, E. B., Kanazawa, Y., Kikuchi, M., Burr, I. M., Stauffacher, W., Renold, A. E., Lambert, A. E., Orci, L., Blondel, B., Rouiller, C., Langslow, D. R., Freeman, B. M., Laube H., Kruger, C., Goberna, R., Fussganger, R., Teller, W., Pfeiffer, E. F., Raptis, S., Legros, F., Conard, V., Metzger, P., Rogister, C., Tinant, A., Lernmark, A., Hellman, B., Sehlin, J., Täljedal, I. -B., Lesobre, B., Hewitt, J., Canivet, J., Levett, R. E., Korp, W., Loubatières, A., Mariani, M. M., Jallet, F., Lundbak, K., Speich, E., Johansen, K., Ørskov, H., Luyckx, A. S., Massi-Benedetti, F., Lefèbvre, P. J., Malaisse, W. J., Brisson, G. R., Marco, J., Diaz-Fierros, M., Baroja, I. M., Villanueva, M. L., Valverde, I., Massara, F., Camanni, F., Molinatti, G. M., McCarroll, A. M., Murphy, R. F., Teale, J. D., Buchanan, K. D., Menzinger, G., Javicoli, M., Fallucca, F., Tamburrano, G., Andreani, D., Michaelis, D., Jutzi, E., Neumann, I., Schulz, B., Hildmann, W., Bibergeil, H., Mincu, I., Campeanu, S., Dumitrescu, C., Mihalache, N., Mincu, T., Parvulescu, M., Georgescu, S., Nuteanu, V., Mogensen, C. E., Hansen, Aa. Prange, Seyer-Hansen, K., Ruth, C. E., Østerby, C. E., Möller, E. B., Bergström, A. L., Wingstrand, H., Persson, S., Morell, B., Froesch, E. R., Mosora, N., Baciu, Tr., Vincze, J., Motocou, M., Simionesco, Ligia, Duma, V., Gligore, V., Muggio, M., Fedele, D., Bagnariol, G., Tiengo, A., Fellin, R., Enzi, G., Rasmussen, S. Munkgaard, Nielsen, Poul Ebbe, Nielsen, S. Levin, Niklas, L., Otto, H., Fuchs, R., Nye, L., Triggs, S., Landon, J., de Mowbray, R., Oelz, O., Oppermann, W., Iwatsuka, H., Ehrenreich, T., Gordon, A., Camerini-Davalos, R. A., Ammon, H. P. T., Steinke, J., Orsetti, A., Bali, J. P., Serre, Mme A., Mirouze, J., Östman, J., Cerasi, E., Efendić, S., Luft, R., Brinck, U., Sabin, J., Sparthe, R., Wübbens, D., Page, M. A., Williamson, D. H., Panten, U., Kriedstein, Ev., Poser, W., Schönborn, J., Hasselblatt, A., Parry, D. G., Taylor, K. W., Polosa, P., Motta, L., Lunetta, M., Pozza, G., Melogli, O., Viberti, G. C., Pappalettera, A. E., Palmieri, G. C., Tognetti, A., Ghidoni, A., Pyörälä, K., Nikkilä, E. A., Lehtovirta, E., Taskinen, M. -R., Pelkonen, R., Siltanen, P., Schröder, K. E., Rothenbuchner, G., Thum, Ch., Fussgänger, R., Sträub, K., Klör, U., Rastogi, G. K., Sinha, M. K., Dash, R. J., Rehfeld, J. F., Stadil, F., Riveline, B., Verry, M., Rosak, C., Bartelt, K. M., Haupt, E., Beyer, J., Schöffling, K., Rosselin, G., Valleron, A. J., Papoz, L., Birk, J., Loos, U., Rudas, B., Wick, G., Samsel, J., Karmann, H., Schatz, H., Rahman, Y. Abdel, Hinz, M., Katsilambros, N., Maier, V., Fehm, H. L., Schenk, K. E., Quabbe, H. J., Klemens, U., Schröder, R., Schennetten, Felix P. N., Schlichtkrull, J., Scandellari, C., Conte, N., Federspil, G., Frezzato, S., Trisotto, A., Scott, R. D. M., Prud'homme, M., Kipnis, D. M., Bricker, N. S., Klahr, S., Skrabalo, Z., Smith, M. J., Hall, M. R. P., Sodovez, J. C., Sodovez-Goffaux, F., Dunbar, J. C., Foà, P. P., Spaethe, R., Meyer, B., Srivastava, M. C., Sönksen, P. H., Tompkins, C. V., Nabarro, J. D. N., Balant, L., Amherdt, M., Cameron, D. P., Steingaszner, O., Kammerer, L., Bretán, M., Sterne, J., Guilcher, S. Le, Rousselet, M., Stimmler, L., Snodgrass, G. J. A. I., Sutherland, Hamish, Tohobroutsky, G., Assan, R., Tompkins, C. V., Track, N. S., Trap-Jensen, J., Turner, M. R., Heard, C. R. C., Reeds, P. J., Munday, K. A., Vague, P., Oliver, C., Jacquet, P., Vague, J., Warnet, J. M., Claude, J. R., Rathery, M., Lozano, I., van Assche, F. A., van't Laar, A., Vigas, M., Haist, R. E., Braun, W., Drucker, W. R., Vitelli, A., Giangrandi, E., Fusco, E., Scaroina, F., Waldhäusl, W. K., Weiss, L., Löffler, G., Schirmann, A., Wieland, O., Westermark, Per, and Woodroffe, F. J.

Published
1972
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17. Sunday, 18 July 2010

Author

Schuchardt, M., primary, Toelle, M., additional, Huang, T., additional, Wiedon, A., additional, Van Der Giet, M., additional, Mill, C., additional, George, S., additional, Jeremy, J., additional, Santulli, G., additional, Illario, M., additional, Cipolletta, E., additional, Sorriento, D., additional, Del Giudice, C., additional, Anastasio, A., additional, Trimarco, B., additional, Iaccarino, G., additional, Jobs, A., additional, Wagner, C., additional, Kurtz, A., additional, De Wit, C., additional, Koller, A., additional, Suvorava, T., additional, Weber, M., additional, Dao, V., additional, Kojda, G., additional, Tsaousi, A., additional, Lyon, C., additional, Williams, H., additional, Barth, N., additional, Loot, A., additional, Fleming, I., additional, Keul, P., additional, Lucke, S., additional, Graeler, M., additional, Heusch, G., additional, Levkau, B., additional, Biessen, E., additional, De Jager, S., additional, Bermudez-Pulgarin, B., additional, Bot, I., additional, Abia, R., additional, Van Berkel, T., additional, Renger, A., additional, Noack, C., additional, Zafiriou, M., additional, Dietz, R., additional, Bergmann, M., additional, Zelarayan, L., additional, Hammond, J., additional, Hamelet, J., additional, Van Assche, T., additional, Belge, C., additional, Vanderper, A., additional, Langin, D., additional, Herijgers, P., additional, Balligand, J., additional, Perrot, A., additional, Neubert, M., additional, Posch, M., additional, Oezcelik, C., additional, Waldmuller, S., additional, Berger, F., additional, Scheffold, T., additional, Bouvagnet, P., additional, Ozcelik, C., additional, Lebreiro, A., additional, Martins, E., additional, Lourenco, P., additional, Cruz, C., additional, Martins, M., additional, Bettencourt, P., additional, Maciel, M., additional, Abreu-Lima, C., additional, Pilichou, K., additional, Bauce, B., additional, Rampazzo, A., additional, Carturan, E., additional, Corrado, D., additional, Thiene, G., additional, Basso, C., additional, Piccini, I., additional, Fortmueller, L., additional, Kuhlmann, M., additional, Schaefers, M., additional, Carmeliet, P., additional, Kirchhof, P., additional, Fabritz, L., additional, Sanchez, J., additional, Rodriguez-Sinovas, A., additional, Agullo, E., additional, Garcia-Dorado, D., additional, Lymperopoulos, A., additional, Rengo, G., additional, Gao, E., additional, Zincarelli, C., additional, Koch, W., additional, Morgan, P., additional, Diez, A., additional, Perez, N., additional, Cingolani, H., additional, Zahradnikova, A., additional, Polakova, E., additional, Zahradnik, I., additional, Fluschnik, N., additional, Sossalla, S., additional, Ort, K., additional, Neef, S., additional, Hasenfuss, G., additional, Maier, L., additional, Weinert, S., additional, Poitz, D., additional, Herold, J., additional, Schmeisser, A., additional, Strasser, J., additional, Braun-Dullaeus, R., additional, Nazari-Jahantigh, M., additional, Weber, C., additional, Schober, A., additional, Leuner, A., additional, Eichhorn, B., additional, Ravens, U., additional, Morawietz, H., additional, Babes, E., additional, Babes, V., additional, Popescu, M., additional, Ardelean, A., additional, Rus, M., additional, Bustea, C., additional, Gwozdz, P., additional, Csanyi, G., additional, Luzak, B., additional, Gajda, M., additional, Mateuszuk, L., additional, Chmura-Skirlinska, A., additional, Watala, C., additional, Chlopicki, S., additional, Kierzkowska, I., additional, Sulicka, J., additional, Kwater, A., additional, Strach, M., additional, Surdacki, A., additional, Siedlar, M., additional, Grodzicki, T., additional, Olieslagers, S., additional, Pardali, L., additional, Tchaikovski, V., additional, Ten Dijke, P., additional, Waltenberger, J., additional, Renner, M., additional, Redwan, B., additional, Winter, M., additional, Panzenboeck, A., additional, Jakowitsch, J., additional, Sadushi-Kolici, R., additional, Bonderman, D., additional, Lang, I., additional, Toso, A., additional, Tanini, L., additional, Pizzetti, T., additional, Leoncini, M., additional, Maioli, M., additional, Tedeschi, D., additional, Oliviero, C., additional, Bellandi, F., additional, Casprini, P., additional, Amato, M., additional, Molins, B., additional, Pena, E., additional, Badimon, L., additional, Ferreiro Gutierrez, J., additional, Ueno, M., additional, Alissa, R., additional, Dharmashankar, K., additional, Capodanno, D., additional, Desai, B., additional, Bass, T., additional, Angiolillo, D., additional, Chabielska, E., additional, Gromotowicz, A., additional, Szemraj, J., additional, Stankiewicz, A., additional, Zakrzeska, A., additional, Mohammed, S., additional, Molla, F., additional, Soldo, A., additional, Russo, I., additional, Germano, G., additional, Balconi, G., additional, Staszewsky, L., additional, Latini, R., additional, Lynch, F., additional, Austin, C., additional, Prendergast, B., additional, Keenan, D., additional, Malik, R., additional, Izzard, A., additional, Heagerty, A., additional, Czikora, A., additional, Lizanecz, E., additional, Rutkai, I., additional, Boczan, J., additional, Porszasz, R., additional, Papp, Z., additional, Edes, I., additional, Toth, A., additional, Colantuoni, A., additional, Vagnani, S., additional, Lapi, D., additional, Maroz-Vadalazhskaya, N., additional, Koslov, I., additional, Shumavetz, V., additional, Glibovskaya, T., additional, Ostrovskiy, Y., additional, Koutsiaris, A., additional, Tachmitzi, S., additional, Kotoula, M., additional, Giannoukas, A., additional, Tsironi, E., additional, Darago, A., additional, Orosz, P., additional, Megyesi, Z., additional, Schudeja, S., additional, Matschke, K., additional, Deussen, A., additional, Castro, M., additional, Cena, J., additional, Walsh, M., additional, Schulz, R., additional, Poddar, K., additional, Rha, S., additional, Ramasamy, S., additional, Park, J., additional, Choi, C., additional, Seo, H., additional, Park, C., additional, Oh, D., additional, Almeida, J., additional, Pimenta, S., additional, Bernardes, J., additional, Machado, J., additional, Sabatasso, S., additional, Laissue, J., additional, Hlushchuk, R., additional, Brauer-Krisch, E., additional, Bravin, A., additional, Blattmann, H., additional, Michaud, K., additional, Djonov, V., additional, Hirschberg, K., additional, Tarcea, V., additional, Pali, S., additional, Korkmaz, S., additional, Loganathan, S., additional, Merkely, B., additional, Karck, M., additional, Szabo, G., additional, Pagliani, L., additional, Faggin, E., additional, Rattazzi, M., additional, Puato, M., additional, Presta, M., additional, Grego, F., additional, Deriu, G., additional, Pauletto, P., additional, Kaiser, R., additional, Albrecht, K., additional, Schgoer, W., additional, Theurl, M., additional, Beer, A., additional, Wiedemann, D., additional, Steger, C., additional, Bonaros, N., additional, Kirchmair, R., additional, Kharlamov, A., additional, Cabaravdic, M., additional, Breuss, J., additional, Uhrin, P., additional, Binder, B., additional, Fiordaliso, F., additional, Maggioni, M., additional, Biondi, A., additional, Masson, S., additional, Cervo, L., additional, Francke, A., additional, Soenke, W., additional, Strasser, R., additional, Hecht, N., additional, Vajkoczy, P., additional, Woitzik, J., additional, Hackbusch, D., additional, Gatzke, N., additional, Duelsner, A., additional, Tsuprykov, O., additional, Slavic, S., additional, Buschmann, I., additional, Kappert, K., additional, Massaro, M., additional, Scoditti, E., additional, Carluccio, M., additional, Storelli, C., additional, Distante, A., additional, De Caterina, R., additional, Barandi, L., additional, Harmati, G., additional, Simko, J., additional, Horvath, B., additional, Szentandrassy, N., additional, Banyasz, T., additional, Magyar, J., additional, Nanasi, P., additional, Kaya, A., additional, Uzunhasan, I., additional, Yildiz, A., additional, Yigit, Z., additional, Turkoglu, C., additional, Doisne, N., additional, Zannad, N., additional, Hivert, B., additional, Cosnay, P., additional, Maupoil, V., additional, Findlay, I., additional, Virag, L., additional, Kristof, A., additional, Koncz, I., additional, Szel, T., additional, Jost, N., additional, Biliczki, P., additional, Papp, J., additional, Varro, A., additional, Bukowska, A., additional, Skopp, K., additional, Hammwoehner, M., additional, Huth, C., additional, Bode-Boeger, S., additional, Goette, A., additional, Workman, A., additional, Dempster, J., additional, Marshall, G., additional, Rankin, A., additional, Revnic, C., additional, Ginghina, C., additional, Revnic, F., additional, Yakushev, S., additional, Petrushanko, I., additional, Makhro, A., additional, Segato Komniski, M., additional, Mitkevich, V., additional, Makarov, A., additional, Gassmann, M., additional, Bogdanova, A., additional, Rutkovskiy, A., additional, Mariero, L., additional, Stenslokken, K., additional, Valen, G., additional, Vaage, J., additional, Dizayee, S., additional, Kaestner, S., additional, Kuck, F., additional, Piekorz, R., additional, Hein, P., additional, Matthes, J., additional, Nurnberg, B., additional, Herzig, S., additional, Hertel, F., additional, Switalski, A., additional, Bender, K., additional, Kienitz, M.-C., additional, Pott, L., additional, Fornai, L., additional, Angelini, A., additional, Erika Amstalden Van Hove, E., additional, Fedrigo, M., additional, Heeren, R., additional, Kruse, M., additional, Pongs, O., additional, Lehmann, H., additional, Martens-Lobenhoffer, J., additional, Roehl, F., additional, Radicke, S., additional, Cotella, C., additional, Sblattero, D., additional, Schaefer, M., additional, Wettwer, E., additional, Santoro, C., additional, Seyler, C., additional, Kulzer, M., additional, Zitron, E., additional, Scholz, E., additional, Welke, F., additional, Thomas, D., additional, Karle, C., additional, Schmidt, K., additional, Dobrev, D., additional, Houshmand, N., additional, Menesi, D., additional, Cotella, D., additional, Szuts, V., additional, Puskas, L., additional, Kiss, I., additional, Deak, F., additional, Tereshchenko, S., additional, Gladyshev, M., additional, Kalachova, G., additional, Syshchik, N., additional, Gogolashvili, N., additional, Dedok, E., additional, Evert, L., additional, Wenzel, J., additional, Brandenburger, M., additional, Bogdan, R., additional, Richardt, D., additional, Reppel, M., additional, Hescheler, J., additional, Dendorfer, A., additional, Terlau, H., additional, Wiegerinck, R., additional, Galvez-Monton, C., additional, Jorge, E., additional, Martinez, R., additional, Ricart, E., additional, Cinca, J., additional, Bagavananthem Andavan, G., additional, Lemmens Gruber, R., additional, Brack, K., additional, Coote, J., additional, Ng, G., additional, Daimi, H., additional, Haj Khelil, A., additional, Neji, A., additional, Ben Hamda, K., additional, Maaoui, S., additional, Aranega, A., additional, Chibani, J., additional, Franco Jaime, D., additional, Tanko, A.-S., additional, Daniel, J.-M., additional, Bielenberg, W., additional, Stieger, P., additional, Tillmanns, H., additional, Sedding, D., additional, Fortini, C., additional, Toffoletto, B., additional, Fucili, A., additional, Beltrami, A., additional, Fiorelli, V., additional, Francolini, G., additional, Ferrari, R., additional, Beltrami, C., additional, Castellani, C., additional, Ravara, B., additional, Tavano, R., additional, Vettor, R., additional, De Coppi, P., additional, Papini, E., additional, Gunetti, M., additional, Fagioli, F., additional, Suffredini, S., additional, Sartiani, L., additional, Stillitano, F., additional, Mugelli, A., additional, Cerbai, E., additional, Krausgrill, B., additional, Halbach, M., additional, Soemantri, S., additional, Schenk, K., additional, Lange, N., additional, Saric, T., additional, Muller-Ehmsen, J., additional, Kavanagh, D., additional, Zhao, Y., additional, Yemm, A., additional, Kalia, N., additional, Wright, E., additional, Farrell, K., additional, Wallrapp, C., additional, Geigle, P., additional, Lewis, A., additional, Stratford, P., additional, Malik, N., additional, Holt, C., additional, Raths, M., additional, Zagallo, M., additional, Luni, C., additional, Serena, E., additional, Cimetta, E., additional, Zatti, S., additional, Giobbe, G., additional, Elvassore, N., additional, Zaglia, T., additional, Zambon, A., additional, Gordon, K., additional, Mioulane, M., additional, Foldes, G., additional, Ali, N., additional, Harding, S., additional, Gorbe, A., additional, Szunyog, A., additional, Varga, Z., additional, Pirity, M., additional, Rungaruniert, S., additional, Dinnyes, A., additional, Csont, T., additional, Ferdinandy, P., additional, Iqbal, A., additional, Schneider, M. D., additional, Khodjaeva, E., additional, Ibadov, R., additional, Khalikulov, K., additional, Mansurov, A., additional, Astvatsatryan, A., additional, Senan, M., additional, Nemeth, A., additional, Lenkey, Z., additional, Ajtay, Z., additional, Cziraki, A., additional, Sulyok, E., additional, Horvath, I., additional, Lobenhoffer, J., additional, Bode-Boger, S., additional, Li, J., additional, He, Y., additional, Yang, X., additional, Wang, F., additional, Xu, H., additional, Li, X., additional, Zhao, X., additional, Lin, Y., additional, Juszynski, M., additional, Ciszek, B., additional, Jablonska, A., additional, Stachurska, E., additional, Ratajska, A., additional, Atkinson, A., additional, Inada, S., additional, Sleiman, R., additional, Zhang, H., additional, Boyett, M., additional, Dobrzynski, H., additional, Fedorenko, O., additional, Hao, G., additional, Yanni, J., additional, Buckley, D., additional, Anderson, R., additional, Ma, Y., additional, Ma, X., additional, Hu, Y., additional, Yang, Y., additional, Huang, D., additional, Liu, F., additional, Huang, Y., additional, Liu, C., additional, Jedrzejczyk, T., additional, Balwicki, L., additional, Wierucki, L., additional, Zdrojewski, T., additional, Agarkova, I., additional, Vogel, J., additional, Korybalska, K., additional, Pyda, M., additional, Witowski, J., additional, Ibatov, A., additional, Sozmen, N., additional, Seymen, A., additional, Tuncay, E., additional, Turan, B., additional, Chen, B., additional, Houston-Feenstra, L., additional, Chiong, J. R., additional, Jutzy, K., additional, Furundzija, V., additional, Kaufmann, J., additional, Meyborg, H., additional, Fleck, E., additional, Stawowy, P., additional, Ksiezycka-Majczynska, E., additional, Lubiszewska, B., additional, Kruk, M., additional, Kurjata, P., additional, Ruzyllo, W., additional, Driesen, R., additional, Coenen, T., additional, Fagard, R., additional, Sipido, K., additional, Petrov, V., additional, Aksentijevic, D., additional, Lygate, C., additional, Makinen, K., additional, Sebag-Montefiore, L., additional, Medway, D., additional, Schneider, J., additional, Neubauer, S., additional, Gasser, R., additional, Holzwart, E., additional, Rainer, P., additional, Von Lewinski, D., additional, Maechler, H., additional, Gasser, S., additional, Roessl, U., additional, Pieske, B., additional, Krueger, J., additional, Kintscher, U., additional, Podramagi, T., additional, Paju, K., additional, Piirsoo, A., additional, Roosimaa, M., additional, Kadaja, L., additional, 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additional, Khanna, N., additional, O'shea, K., additional, Kristian, T., additional, Hecker, P., additional, Des Rosiers, R., additional, Fiskum, G., additional, Fernandez-Alfonso, M., additional, Guzman-Ruiz, R., additional, Somoza, B., additional, Gil-Ortega, M., additional, Attane, C., additional, Castan-Laurell, I., additional, Valet, P., additional, Ruiz-Gayo, M., additional, Denissevich, T., additional, Schrepper, A., additional, Schwarzer, M., additional, Amorim, P., additional, Schoepe, M., additional, Mohr, F., additional, Doenst, T., additional, Chiellini, G., additional, Ghelardoni, S., additional, Saba, A., additional, Marchini, M., additional, Frascarelli, S., additional, Raffaelli, A., additional, Scanlan, T., additional, Zucchi, R., additional, Van Den Akker, N., additional, Molin, D., additional, Kolk, F., additional, Jeukens, F., additional, Olde Engberink, R., additional, Post, M., additional, Verbruggen, S., additional, Schulten, H., additional, Rochais, F., additional, Kelly, R., additional, Aberg, M., additional, Johnell, M., additional, Wickstrom, M., additional, Siegbahn, A., additional, Dimitrakis, P., additional, Groppalli, V., additional, Ott, D., additional, Seifriz, F., additional, Suter, T., additional, Zuppinger, C., additional, Kashcheyeu, Y., additional, Mueller, R., additional, Wiesen, M., additional, Gruendemann, D., additional, Falcao-Pires, I., additional, Fontes-Sousa, A., additional, Lopes-Conceicao, L., additional, Bras-Silva, C., additional, Leite-Moreira, A., additional, Bukauskas, F., additional, Palacios-Prado, N., additional, Norheim, F., additional, Raastad, T., additional, Thiede, B., additional, Drevon, C., additional, Haugen, F., additional, Lindner, D., additional, Westermann, D., additional, Zietsch, C., additional, Schultheiss, H.-P., additional, Tschoepe, C., additional, Horn, M., additional, Graham, H., additional, Hall, M., additional, Richards, M., additional, Clarke, J., additional, Dibb, K., additional, Trafford, A., additional, Cheng, C.-F., additional, Lin, H., additional, Eigeldiger-Berthou, S., additional, Buntschu, P., additional, Frobert, A., additional, Flueck, M., additional, Tevaearai, H., additional, Kadner, A., additional, Mikhailov, A., additional, Torrado, M., additional, Centeno, A., additional, Lopez, E., additional, Lourido, L., additional, Castro Beiras, A., additional, Popov, T., additional, Srdanovic, I., additional, Petrovic, M., additional, Canji, T., additional, Kovacevic, M., additional, Jovelic, A., additional, Sladojevic, M., additional, Panic, G., additional, Kararigas, G., additional, Fliegner, D., additional, Regitz-Zagrosek, V., additional, De La Rosa Sanchez, A., additional, Dominguez, J., additional, Sedmera, D., additional, Franco, D., additional, Medunjanin, S., additional, Burgbacher, F., additional, Han, W., additional, Zhang, J., additional, Gao, X., additional, Bayliss, C., additional, Song, W., additional, Stuckey, D., additional, Dyer, E., additional, Leung, M.-C., additional, Monserrat, L., additional, Marston, S., additional, Fusco, A., additional, Paillard, M., additional, Liang, J., additional, Strub, G., additional, Gomez, L., additional, Hait, N., additional, Allegood, J., additional, Lesnefsky, E., additional, Spiegel, S., additional, Zuchi, C., additional, Coiro, S., additional, Bettini, M., additional, Ciliberti, G., additional, Mancini, I., additional, Tritto, I., additional, Becker, L., additional, Ambrosio, G., additional, Adam, T., additional, Sharp, S., additional, Opie, L., additional, Lecour, S., additional, Khaliulin, I., additional, Parker, J., additional, Halestrap, A., additional, Kandasamy, A., additional, Osterholt, M., additional, Miro-Casas, E., additional, Boengler, K., additional, Menazza, S., additional, Canton, M., additional, Sheeran, F., additional, Di Lisa, F., additional, Pepe, S., additional, Borchi, E., additional, Manni, M., additional, Bargelli, V., additional, Giordano, C., additional, D'amati, G., additional, Nediani, C., additional, Raimondi, L., additional, Micova, P., additional, Balkova, P., additional, Kolar, F., additional, Neckar, J., additional, Novak, F., additional, Novakova, O., additional, Schuchardt, M., additional, Pruefer, N., additional, Pruefer, J., additional, Jankowski, V., additional, Jankowski, J., additional, Su, Y., additional, Zervou, S., additional, Seidel, B., additional, Radovits, T., additional, Barnucz, E., additional, Aggeli, I., additional, Kefaloyianni, E., additional, Beis, I., additional, Gaitanaki, C., additional, Lacerda, L., additional, Somers, S., additional, Paur, H., additional, Nikolaev, V., additional, Lyon, A., additional, Silva, S., additional, Gomes, M., additional, Ferreira, P., additional, Capuano, V., additional, Ferron, L., additional, Ruchon, Y., additional, Ben Mohamed, F., additional, Renaud, J.-F., additional, Goncalves, N., additional, Gavina, C., additional, Pinho, S., additional, Moura, C., additional, Amorim, M., additional, Pinho, P., additional, Christ, T., additional, Molenaar, P., additional, Kaumann, A., additional, Kletsiou, E., additional, Giannakopoulou, M., additional, Bozas, E., additional, Iliodromitis, E., additional, Anastasiou-Nana, M., additional, Papathanassoglou, E., additional, Chottova Dvorakova, M., additional, Mistrova, E., additional, Slavikova, J., additional, Hynie, S., additional, Sida, P., additional, Klenerova, V., additional, Zakrzewicz, A., additional, Hoffmann, C., additional, Hohberg, M., additional, Chlench, S., additional, Maroski, J., additional, Drab, M., additional, Siegel, G., additional, Pries, A., additional, Schrot, G., additional, Wilck, N., additional, Fechner, M., additional, Arias, A., additional, Meiners, S., additional, Baumann, G., additional, Stangl, V., additional, Stangl, K., additional, Ludwig, A., additional, Christ, A., additional, Eijgelaar, W., additional, Daemen, M., additional, Penfold, M., additional, Schall, T., additional, Hintenberger, R., additional, Kaun, C., additional, Pfaffenberger, S., additional, Maurer, G., additional, Huber, K., additional, Wojta, J., additional, Demyanets, S., additional, Titov, V., additional, Chin-Dusting, J., additional, Vaisman, B., additional, Khong, S., additional, Remaley, A., additional, Andrews, K., additional, Hoeper, A., additional, Khalid, A., additional, Fuglested, B., additional, Aasum, E., additional, Larsen, T., additional, Diebold, I., additional, Petry, A., additional, Djordjevic, T., additional, Belaiba, R., additional, Fratz, S., additional, Hess, J., additional, Kietzmann, T., additional, Goerlach, A., additional, Chess, D., additional, Walsh, K., additional, Van Der Velden, J., additional, Moreira-Goncalves, D., additional, Paulus, W., additional, Niessen, H., additional, Perlini, S., additional, Azibani, F., additional, Tournoux, F., additional, Fazal, L., additional, Polidano, E., additional, Merval, R., additional, Chatziantoniou, C., additional, Samuel, J., additional, Delcayre, C., additional, Mgandela, P., additional, Brooksbank, R., additional, Maswanganyi, T., additional, Woodiwiss, A., additional, Norton, G., additional, Makaula, S., additional, Bucciantini, M., additional, Spinelli, V., additional, Coppini, R., additional, Russo, E., additional, Stefani, M., additional, Sukumaran, V., additional, Watanabe, K., additional, Ma, M., additional, Thandavarayan, R., additional, Azrozal, W., additional, Sari, F., additional, Shimazaki, H., additional, Kobayashi, Y., additional, Roleder, T., additional, Golba, K., additional, Deja, M., additional, Malinowski, M., additional, Wos, S., additional, Grebe, M., additional, Preissner, K., additional, Ercan, E., additional, Guven, A., additional, Asgun, F., additional, Ickin, M., additional, Ercan, F., additional, Kaplan, A., additional, Yavuz, O., additional, Bagla, S., additional, Kuka, J., additional, Vilskersts, R., additional, Vavers, E., additional, Liepins, E., additional, Dambrova, M., additional, Duerr, G., additional, Suchan, G., additional, Heuft, T., additional, Klaas, T., additional, Zimmer, A., additional, Welz, A., additional, Fleischmann, B., additional, Dewald, O., additional, Voelkl, J., additional, Haubner, B., additional, Kremser, C., additional, Mayr, A., additional, Klug, G., additional, Reiner, M., additional, Pachinger, O., additional, Metzler, B., additional, Pisarenko, O., additional, Shulzhenko, V., additional, Pelogeykina, Y., additional, Khatri, D., additional, Studneva, I., additional, Bencsik, P., additional, Kocsis, G., additional, Shamloo, M., additional, Woodburn, K., additional, Szucs, G., additional, Kupai, K., additional, Csont, C., additional, Kocsisne Fodor, G., additional, Monostori, P., additional, and Turi, S., additional

Published
2010
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18. Quantitative process evaluation of a community-based HIV/AIDS behavioural intervention in rural Uganda

Author

Kinsman, John, Kamali, A, Kanyesigye, E, Kamulegeya, I, Basajja, V, Nakiyingi, J, Schenk, K, Whitworth, J, Kinsman, John, Kamali, A, Kanyesigye, E, Kamulegeya, I, Basajja, V, Nakiyingi, J, Schenk, K, and Whitworth, J

Abstract

This paper describes the implementation of a large community-based HIV/AIDS behavioural intervention in rural Uganda and presents 4 years' worth of quantitative process data. The intervention involved 560 field-based workers (57% male, 76% subsistence farmers, mean age 35 years), supervised by six central staff. Intervention channels included drama and video shows, Community Educators (CEs), as well as leaflet and condom distribution. Activities focused on one or more of 16 key topics. In total, 392 000 attendances (51% female) were recorded--a mean of over 6 for each of the 64 000 target adults--at 81 000 activities, with CEs attracting 71% of the total attendance; 164 000 leaflets and 242 000 condoms were also distributed. The annual cost of the intervention per target individual was approximately US$1.76. Our voluntary workforce experienced an annual attrition rate of 11%, with 'stable' workers more likely to be older, married or opinion leaders in their community than those who dropped out. We calculate that even a significant increase in the proportion of female field workers would have made little difference either to the sex ratio of attendees or to overall attendance. In spite of some initial resistance to the intervention, particularly in relation to condoms, we have demonstrated that people in rural Africa can accept and actively participate in the dissemination of HIV/AIDS prevention messages throughout their own communities.

Published
2002
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31. EFFECTS OF MASSAGE UNDER HYPOXIC CONDITIONS ON EXERCISE-INDUCED MUSCLE DAMAGE AND PHYSICAL STRAIN INDICES IN PROFESSIONAL SOCCER PLAYERS.

Author

Gatterer, H., Schenk, K., Wille, M., Burtscher, M., and Murnig, P.

Abstract

Reports based on experiences from masseurs and players, mostly without any scientific background, suggest that the combination of a classical regeneration method (i.e. massage) with exposure to hypoxia may enhance regeneration in soccer. The aim of this study was to evaluate whether this specific combination could affect blood parameters related to muscle damage and physical strain after a soccer game. Approximately 15 hours after two separate championship games, 10 professional male outfield players of the first Austrian division were exposed to normobaric hypoxia (F1O2 13.5% ~ 4000m) or normoxia for 1 hour (30 minutes rest followed by 30 min massage) (cross-over design). Creatine kinase (CK), urea and uric acid (UA) were measured 4 days before the first game, and 15 and 63 hours after the two games. Match play increased CK values independently of the intervention. No effect of the massage in combination with hypoxia was seen. A trend was found between Δ UA ([UA] 48 hours after exposure minus [UA] before exposure) in response to hypoxia and SaO2 measured in hypoxia (r=0.612, p=0.06). Results show that massage under hypoxic conditions had no additional positive effect on the measured parameters compared to massage alone. Solely the trend of a relationship for Δ UA and SaO2 might indicate that redox alterations are a potential consequence of hypoxic exposure. [ABSTRACT FROM AUTHOR]

Published
2013
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32. Boomdiameterbepalingen

Author

Hagman, K. and Schenk, K.

Subjects
girth, work study, meting, arbeidskunde, forestry, suriname, measurement, diameter, omtrek, bosbouw
Published
1982

34. A Language Comparison. A Comparison of the Properties of the Programming Languages ALGOL 68, CAMAC-IML, Coral 66, PAS 1, PEARL, PL/1, PROCOL, RTL/2 in Relation to Real Time Programming

Author

PURDUE UNIV LAFAYETTE IND PURDUE LAB FOR APPLIED INDUSTRIAL CONTROL, Roessler,R, Schenk,K, PURDUE UNIV LAFAYETTE IND PURDUE LAB FOR APPLIED INDUSTRIAL CONTROL, Roessler,R, and Schenk,K

Abstract

A comparison of the key features of eight well known real time programming languages in relation to their use for industrial computer systems. (Author)

Published
1976

36. Surfactant protein D and KL-6 serum levels in systemic sclerosis: Correlation with lung and systemic involvement

Author

Francesco Bonella, Volpe, A., Caramaschi, P., Nava, C., Ferrari, P., Schenk, K., Ohshimo, S., Costabel, U., and Ferrari, M.

Subjects
Male, Scleroderma, Systemic, Pulmonary Fibrosis, Mucin-1, Medizin, Enzyme-Linked Immunosorbent Assay, Middle Aged, Prognosis, Pulmonary Surfactant-Associated Protein D, Severity of Illness Index, Respiratory Function Tests, lung, pneumoproteins, Humans, Systemic sclerosis, Female, Biomarkers, Autoantibodies, Follow-Up Studies
Abstract

The aim of this study was to investigate the relationship between SP-D and KL-6 serum concentrations and the extent of interstitial lung involvement, as measured by a quantitative HRCT score and the functional impairment, in patients with systemic sclerosis (SSc). Moreover we analysed the association between these lung-specific biomarkers and skin involvement, anti-Scl-70 antibody titres and an index of disease activity.Serum SP-D, KL-6 and anti-Scl-70 concentrations were determined by ELISA in 25 SSc patients. Disease activity and lung function parameters were assessed, and the extent of ILD was measured by a HRCT score.SP-D and KL-6 concentrations were higher in patients with SSc and lung fibrosis than in healthy controls. KL-6 correlated positively with the HRCT-fibrosis score (r=0.68, p0.001), SP-D showed a weaker correlation (r=0.44, p=0.025). Increased KL-6 concentrations were associated with decreased DLCO and decreased FVC in SSc patients, SP-D showed no association. Furthermore KL-6, but not SP-D, showed a strong association with skin involvement as expressed by the modified Rodnan skin score (r=0.71, p0.0001) and a disease activity index (r=0.73, p0.0001).KL-6 is more strongly associated than SP-D with the HRCT-fibrosis score, and, different from SP-D, it correlates with skin involvement and disease activity. We suggest that KL-6 may be a useful biomarker in the assessment of scleroderma patients.

41. Anstössige Bilder? Medienstrategien der Interkulturalität

Author

Loren, Scott, Sinn, Christian, Schenk, K., Cornejo, R., Szabo, L.V., and PHSG - Studienbereich Sprachen und Literatur

Subjects
education, visuelle Kultur, Zensur, Interkulturalität, Medien, Kulturpolitik, Intermedialität, Rassismus, Sexismus, cultural studies, political science, social sciences
Abstract

Geschichte und Erinnerungen sind jedoch überall gegenwärtig und werden als Ressourcen der Macht genutzt. Je mehr Gegenregierungen, widersprüchliche Bilder und konkurrierende Erinnerungen die Diskurse in beide Regionen prägen, umso mehr schaffen sie die notwendigen Voraussetzungen für eine pluralistische Erinnerungskultur.

Published
2016

42. Do personal, familial or counseling factors influence the choice for prophylactic mastectomy and/or bilateral salpingo-oöphorectomy of female BRCA mutation carriers?

Author

Caanen, B. A., Gielen, M., GomezGarcia, E. B., Kruitwagen, R. F., Keymeulen, K. B., Ter Haar-van Eck, S. A., Schenk, K., and Helderman-van den Enden, A.

Subjects
*BREAST cancer research, *BRCA genes, *OVARIAN cancer, *LOGISTIC regression analysis, *MASTECTOMY
Abstract

Background: A germline mutation in the BRCA1 or BRCA2 gene predisposes for breast- and ovarian cancer. Female carriers of a BRCA-mutation 25 years of age, need to choose between surveillance and prophylactic surgery for their breasts and ovaries. Until now it remains unclear which factors contribute to these choices. Aim: The aim of our study was to investigate whether psychosocial or care provider-related factors influence the choice for prophylactic surgery in BRCA mutation carriers. Design: The cohort consisted of 635 women (mean age 46 (18-90) years), all living in the South East of The Netherlands and counseled between 1994 and April 2012. 323 women were carrier of a BRCA1 and 312 of a BRCA2 mutation. 239 had breast cancer, 38 ovarian cancer, 28 had breast and ovarian cancer and 330 women had no cancer history. Univariable and multivariable logistic regression analyses were performed with either breast surveillance vs. mastectomy or ovarian surveillance vs. bilateral salpingo- oöphorectomy (BSO) as outcome. The following factors were investigated: * - Personal: age at time of BRCA test and cancer history, * - Familial: presence of first degree relative with breast and/or ovarian cancer, age of the relative and the BRCA carrier at time of cancer diagnosis in this relative, whether the BRCA carrier had children and if so age of the children(< 18 or 18), * - Counseling: professional responsible of counseling (clinical geneticist vs genetic counselor), Psychsocial support (if needed) (genetic counselor vs psychologist) and whether the follow up was in specialized multidisciplinary teams or a peripheral hospital. Results: Prophylactic mastectomy was chosen by 132 of the women, breast surveillance by 352 women. BSO was chosen by 268 women, most of them above 40 years of age; ovarian surveillance by 161 women. Ovarian surveillance was the choice of women younger than 40, women with a breast cancer history and older women. Univariable analyses revealed that women more often chose for mastectomy when they had a younger age (OR 0.94 CI 0.919-0.964), breast cancer (OR 4.827 CI 2.843-8.198), children (OR: 1.889 CI 1.085-3.289), especially children under the age of 18 (OR 1.778 CI 1.103-2.866), a first degree relative with cancer (OR 0.41 CI 0.231-0.728) or consulted a psychologist (OR 5.299 CI 1.425-19.703). The choice for mastectomy was not influenced by the counselor or the place where the follow-up was given. Multivariable analysis showed that if all factors were considered together, 3 factors remained significant for choosing mastectomy: age, personal cancer history and first degree relative with cancer factors. No factors were found that influence the choice for preventive measures for ovarian cancer. This was expected because since 2002 all women BRCA carriers where advised to chose BSO above 40 years of age. Conclusion: Personal and familial factors play important roles in the choice for prevention of breast- and ovarian cancer in female BRCA mutation carriers. In our study counseling factors, such as type of counselor or place of follow-up did not influence the choice for prophylactic mastectomy. [ABSTRACT FROM AUTHOR]

Published
2012
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43. Changes in Factors Regulating Serum Sodium Homeostasis During Two Ultra-Endurance Mountain Races of Different Distances: 69km vs. 121km.

Author

Schenk K, Rauch S, Procter E, Grasegger K, Mrakic-Sposta S, and Gatterer H

Abstract

Overdrinking and non-osmotic arginine vasopressin release are the main risk factors for exercise-associated hyponatremia (EAH) in ultra-marathon events. However, particularly during ultra-marathon running in mountainous regions, eccentric exercise and hypoxia, which have been shown to modulate inflammation, hormones regulating fluid homeostasis (hypoxia), and oxidative stress, could contribute to serum sodium changes in a dose-dependent manner. To the best of our knowledge, the contribution of these factors, the extent of which depends on the duration and geographical location of the race, has not been well studied. Twelve male participants (11 finishers) of the short (69km, 4,260m elevation-gain) and 15 male participants (seven finishers) of the long (121km, 7,554m elevation-gain) single-stage Südtirol Ultra Sky-Race took part in this observational field study. Venous blood was drawn immediately before and after the race. Analyses included serum sodium concentration, copeptin (a stable marker for vasopressin), markers of inflammation, muscle damage and oxidative stress. Heart rate was measured during the race and race time was obtained from the race office. During the short and the long competition two and one finishers, respectively showed serum sodium concentrations >145mmol/L. During the long competition, one athlete showed serum sodium concentrations <135mmol/L. Only during the short competition percent changes in serum sodium concentrations of the finishers were related to percent changes in body mass ( r =-0.812, p =0.002), total time ( r =-0.608, p =0.047) and training impulse (TRIMP) ( r =-0.653, p =0.030). Data show a curvilinear (quadratic) relationship between percent changes in serum sodium concentration and body mass with race time when including all runners (short, long, finishers and non-finishers). The observed prevalence of hypo- and hypernatremia is comparable to literature reports, as is the relationship between serum sodium changes and race time, race intensity and body mass changes of the finishers of the short race. The curvilinear relationship indicates that there might be a turning point of changes in serum sodium and body mass changes after a race time of approximately 20h. Since the turning point is represented mainly by non-finishers, regardless of race duration slight decrease in body mass and a slight increase in serum sodium concentration should be targeted to complete the race. Drinking to the dictate of thirst seems an adequate approach to achieve this goal., Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest., (Copyright © 2021 Schenk, Rauch, Procter, Grasegger, Mrakic-Sposta and Gatterer.)

Published
2021
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44. Venous Pooling in Suspension Syndrome Assessed with Ultrasound.

Author

Rauch S, Schenk K, Gatterer H, Erckert M, Oberhuber L, Bliemsrieder B, Dal Cappello T, Brugger H, Paal P, and Strapazzon G

Subjects
Adult, Humans, Male, Syncope, Vasovagal diagnostic imaging, Syncope, Vasovagal etiology, Ultrasonography, Weightlessness adverse effects, Wilderness Medicine, Young Adult, Mountaineering, Oxygen Consumption, Syncope, Vasovagal physiopathology
Abstract

Introduction: Suspension syndrome describes a potentially life-threatening event during passive suspension on a rope. The pathophysiological mechanism is not fully understood; however, the most widespread hypothesis assumes blood pools in the lower extremities, prompting a reduction in cardiac preload and cardiac output and leading to tissue hypoperfusion, loss of consciousness, and death. The aim of this study was to assess venous pooling by ultrasound in simulated suspension syndrome using human subjects., Methods: In this trial, 20 healthy volunteers were suspended in a sit harness for a maximum of 60 min with and without preceding exercise. Venous pooling was assessed by measuring the diameter of the superficial femoral vein (SFV) with ultrasound at baseline in supine and standing positions as well as during and after suspension., Results: SFV diameter increased and blood flow became progressively sluggish. In 30% of the tests, near syncope occurred. However, SFV diameter did not differ between subjects with and without near syncope., Conclusions: Free hanging in a harness leads to rapid venous pooling in the lower limbs. The most important measure to prevent suspension syndrome might be constant movement of the legs., (Copyright © 2019 The Authors. Published by Elsevier Inc. All rights reserved.)

Published
2020
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45. Perinatal mental health care from the user and provider perspective: protocol for a qualitative study in Switzerland.

Author

Berger A, Schenk K, Ging A, Walther S, and Cignacco E

Subjects
Focus Groups, Humans, Needs Assessment, Qualitative Research, Switzerland, Mental Health Services, Perinatal Care
Abstract

Background: Mental disorders in the perinatal period (PMD) can severely harm women and their children if not detected early and treated appropriately. Even though mental health care is covered by health insurance and is used widely by women in the perinatal period in Switzerland, it is not known if the care provided is meeting the needs of the patients and is efficient in the view of health care professionals. The aim of this study is to identify strengths, gaps and requirements for adequate mental health care in the perinatal period from the perspectives of patients and care providers for a wide range of relevant mental disorders., Methods: In the qualitative study we conduct (1) semi-structured single interviews with former PMD patients to obtain narratives about their experiences and needs for health care for their condition. Women are included who have been treated for PMD but are mentally stable at the time of the interview (n = 24). We will stratify the sample by 4 clusters of relevant ICD-10 F-diagnoses, covering the most frequent and the most severe mental disorders. We will further stratify the sample based on whether the women already had experience with psychiatric or psychological health care or not before their last episode of PMD. We will also conduct (2) three interprofessional focus groups with health and social care professionals involved in perinatal care, and a health insurance representative. The focus groups will consist of 5-8 professionals. Data collection and thematic analysis will consider Levesque's et al. (2013) conceptual model on access to health care., Discussion: The study will provide fundamental data on the experiences and perspectives about perinatal mental health care from user and provider perspectives. The study will generate the evidence base needed to develop models of integrated, coordinated, patient- and family-centred care that is accessed by women with various types of PMD., Trial Registration: The study was registered on ClinicalTrials.gov in November 2019 under the identifier NCT04185896.

Published
2020
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46. La version franco-canadienne du « STrengthening the Reporting of OBservational studies in Epidemiology » (STROBE) Statement : L’outil STROBE.

Author

Brosseau L, Guitard P, Laroche C, King J, Barette JA, Cardinal D, Cavallo S, Laferrière L, Lortie-Latreille C, Thibault J, Sutton A, Galipeau R, Tourigny J, Toupin-April K, Loew L, Demers C, Sauvé-Schenk K, Paquet N, Savard J, Lagacé J, Pharand D, and Vaillancourt V

Abstract

Purpose: The main purpose is to produce a French-Canadian translation of the "STrengthening the Reporting of OBservational studies in Epidemiology" (STROBE) Statement under the proposed name of "outil STROBE" and to assess the cross-cultural validity of its content. The secondary purpose is to examine its preliminary interrater reliability. Method: A modified approach to Vallerand's cross-cultural validation methodology was used. First, professional translators and clinical practitioners produced a parallel reverse translation of the "STROBE Statement." Then, a committee of experts (P1) examined the translated versions and created a first experimental draft of the "outil STROBE." This draft was assessed and modified by a second committee of experts (P2). Finally, 32 future professionals doing their master's degree in physiotherapy and occupational therapy assessed this second experimental version of the tool using an ambiguity scale of 8 points (0 meaning "not at all ambiguous" and 7 meaning "extremely ambiguous"). The main co-researchers examined the problematic elements and proposed final modifications. Ten observational studies published in French after 1980 were assessed by two independent raters using the French-Canadian version of the "outil STROBE." The kappa coefficient was used to examine interrater reliability. Results: For the different elements of the final version of the "outil STROBE," the averages on the ambiguity scale varied from 0.0 to 2.4. No element received an average below 2.4, which showed a high level of clarity. The interrater reliability ( n = 2) for the "outil STROBE" is thought to be good for 74% of individual elements, according to the kappa coefficient values obtained. Conclusions: The process's five rigorous steps enabled the production of a valid French-Canadian version of the "STROBE Statement.", Competing Interests: Conflits d’intérêts : Les auteurs n’ont aucun conflit d’intérêts à déclarer.

Published
2019
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47. Validation transculturelle de contenu de la version franco-canadienne de l’échelle COREQ.

Author

King J, Brosseau L, Guitard P, Laroche C, Barette JA, Cardinal D, Cavallo S, Laferrière L, Toupin-April K, Bérubé MÈ, O'Neil J, Castro J, Kidjo C, Fakhry S, Sutton A, Galipeau R, Tourigny J, Lagacé J, Demers C, Paquet N, Pharand D, Loew L, Vaillancourt V, and Sauvé-Schenk K

Abstract

Purpose: The main purpose of this article is to produce a French-Canadian translation of the Consolidated criteria for reporting qualitative studies (COREQ) scale under the proposed name "échelle COREQ" and to assess the transcultural validity of its content. The secondary purpose is to examine the inter-rater reliability of the French-Canadian version of the COREQ scale. Method: A modified approach to Vallerand's methodology (1989) for cross-cultural validation was used. First, a parallel back-translation of the COREQ scale was performed, by both professionals and clinicians. Next, a first committee of experts(P1) examined the translations to create a first draft of the French-Canadian version of the COREQ scale. This draft was then evaluated and modified by a second committee of experts (P2). Finally, 28future professionals (master's students in physiotherapy) rated this second draft of the tool for clarity using a seven-point scale (1:very clear; 7:very ambiguous). The principal co-investigators then reviewed the problematic elements and proposed final changes. Two independent raters used this French-Canadian version of the COREQ scale to assess 13qualitative studies that were published in French after the year2007. The kappa coefficient was used to examine inter-rate reliability. Results: The different elements of the final version of the COREQ scale received an average ambiguity rating between 1.04 and 2.56. These low values show a high level of clarity for the French-Canadian version of the COREQ scale. In relation to the total score of the COREQ scale, inter-rater reliability ( n  = 2) is considered to be average to excellent for 62.5% of individual elements, according to the kappa values obtained. Conclusions: A valid French-Canadian version of the COREQ scale was created using this rigorous five-step process., (© Canadian Physiotherapy Association.)

Published
2019
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48. The prevalence and process of pediatric HIV disclosure: A population-based prospective cohort study in Zimbabwe.

Author

Finnegan A, Langhaug L, Schenk K, Puffer ES, Rusakaniko S, Choi Y, Mahaso S, and Green EP

Subjects
Adolescent, Age Factors, Child, Cohort Studies, Female, Humans, Longitudinal Studies, Male, Middle Aged, Prevalence, Prospective Studies, Social Stigma, Zimbabwe, Caregivers psychology, HIV Infections psychology, Truth Disclosure
Abstract

Introduction: The objective of this study was to estimate the prevalence of pediatric HIV disclosure in rural Zimbabwe and track the process of disclosure over time., Methods: We recruited a population-based sample of 372 caregivers of HIV-positive children ages 9 to 15 to participate in a survey about disclosure. Using data from this cross-sectional sample, we then identified a prospective cohort of 123 caregivers who said their HIV-positive child did not know his or her HIV status, and we followed this non-disclosed cohort of caregivers through two additional waves of data collection over the next 12 months. At each wave, we inquired about the timing and process of disclosure and psychosocial factors related to HIV disclosure., Results: The overall prevalence of disclosure in the cross-sectional sample was 66.9% (95% CI 62.0 to 71.5%). Only 26.9% of children knew how they were infected and that they can transmit the virus to others (i.e. "full disclosure"). Older children were more likely to know their status. Among the non-disclosed caregivers at baseline, nearly 60% of these children learned their HIV status over the course of the 12-month study period, but only 17.1% learned how they were infected and that they can transmit the virus to others. Most caregivers were satisfied with their child's disclosure experience. Caregivers who had not disclosed their child's HIV status to the child worried that disclosure would lead to stigma in the community, provoke questions from their child they would not be able to answer, or cause the child to reject the caregiver in anger., Conclusions: This study suggests that rates of pediatric HIV disclosure may be larger than typically reported, but also reinforces the idea that most children do not know key details about their illness, such as how they were infected and that they can infect others., Competing Interests: The authors have declared that no competing interests exist.

Published
2019
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49. Cosmetic Consequences of Breast-Conserving Treatment for Breast Cancer: Something Worth Talking About.

Author

Brands-Appeldoorn A, Maaskant-Braat S, Schenk K, and Roumen R

Subjects
Adult, Aged, Aged, 80 and over, Female, Humans, Middle Aged, Breast Neoplasms surgery, Mastectomy, Segmental methods
Abstract

Background: Breast-conserving treatment (BCT) for breast cancer can lead to deformation of the treated breast, resulting in patient dissatisfaction with the final cosmetic outcome. Currently, literature on the specific information needs of patients concerning the cosmetic effects of BCT is lacking. The aim of the present study was to investigate the information needs of breast cancer patients regarding the long-term cosmetic outcome after BCT., Subjects, Materials, and Methods: The data from 115 women who had undergone BCT in a general teaching hospital breast cancer unit in The Netherlands were studied. Structured questionnaires and semi-structured interviews were conducted between October 2012 and April 2013. A mixed model of quantitative and qualitative research was used to explore patient-reported information needs. A phenomenological approach was used to analyze the qualitative data., Results: This study shows that women undergoing BCT want to discuss long-term cosmetic effects. Most patients appreciate such information immediately after the diagnosis. Patients indicated that it is also important to pay attention to the cosmetic effects during the follow-up visits, because deformation of the breast can also occur at a later stage. Furthermore, half the patients indicated that they would not likely raise the subject of cosmetic effects of the treatment themselves., Conclusion: Breast cancer patients have a need for long-term attention for cosmetic outcome of BCT, which should be tailored during the treatment and follow-up process., Implications for Practice: Currently, no literature exists concerning patients' needs for information regarding the cosmetic effects of breast-conserving therapy (BCT). Bringing up the cosmetic effects of BCT by health care professionals does not appear to be a standard part of treatment and follow-up. It is expected that the quality of care and life will be improved by providing information and guidance regarding the cosmetic outcome of BCT within the existing structure of the breast cancer pathway. Discussion and visualization of the cosmetic effects prior to treatment will lead to more realistic expectations, and as a result, secondary interventions, such as partial prostheses and plastic surgery, may be easier to discuss and accept., Competing Interests: Disclosures of potential conflicts of interest may be found at the end of this article., (© AlphaMed Press 2018.)

Published
2019
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50. The influence of gestational age in the psychometric testing of the Bernese Pain Scale for Neonates.

Author

Schenk K, Stoffel L, Bürgin R, Stevens B, Bassler D, Schulzke S, Nelle M, and Cignacco E

Subjects
Blood Specimen Collection adverse effects, Female, Humans, Infant, Newborn, Male, Pain etiology, Prospective Studies, Psychometrics, Gestational Age, Pain Measurement methods
Abstract

Background: Assessing pain in neonates is challenging because full-term and preterm neonates of different gestational ages (GAs) have widely varied reactions to pain. We validated the Bernese Pain Scale for Neonates (BPSN) by testing its use among a large sample of neonates that represented all GAs., Methods: In this prospective multisite validation study, we assessed 154 neonates between 24 2/7 and 41 4/7 weeks GA, based on the results of 1-5 capillary heel sticks in their first 14 days of life. From each heel stick, we produced three video sequences: baseline; heel stick; and, recovery. Five blinded nurses rated neonates' pain responses according to the BPSN. The underlying factor structure of the BPSN, interrater reliability, concurrent validity with the Premature Infant Pain Profile-Revised (PIPP-R), construct validity, sensitivity and specificity, and the relationship between behavioural and physiological indicators were explored. We considered GA and gender as individual contextual factors., Results: The factor analyses resulted in a model where the following behaviours best fit the data: crying; facial expression; and, posture. Pain scores for these behavioural items increased on average more than 1 point during the heel stick phases compared to the baseline and recovery phases (p < 0.001). Among physiological items, heart rate was more sensitive to pain than oxygen saturation. Heart rate averaged 0.646 points higher during the heel stick than the recovery phases (p < 0.001). GA increased along with pain scores: for every additional week of gestation, the average increase of behavioural pain score was 0.063 points (SE = 0.01, t = 5.49); average heart rate increased 0.042 points (SE = 0.01, t = 6.15). Sensitivity and specificity analyses indicated that the cut-off should increase with GA. Modified BPSN showed good concurrent validity with the PIPP-R (r = 0.600-0.758, p < 0.001). Correlations between the modified behavioural subscale and the item heart rate were low (r = 0.102-0.379)., Conclusions: The modified BPSN that includes facial expression, crying, posture, and heart rate is a reliable and valid tool for assessing acute pain in full-term and preterm neonates, but our results suggest that adding different cut-off points for different GA-groups will improve the BPSN's clinical usefulness., Trial Registration: The study was retrospectively registered in the database of Clinical Trial gov. Study ID-number: NCT 02749461 . Registration date: 12 April 2016.

Published
2019
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