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10 results on '"Sardiña González, Cristina"'

2. Real-Life Impact of Glucocorticoid Treatment in COVID-19 Mortality: A Multicenter Retrospective Study

Author

Muñoz-Gómez, Ana, Fernández-Cruz, Ana, Lavilla-Olleros, Cristina, Giner-Galvañ, Vicente, Ausín-García, Cristina, Wikman, Philip, Bendala-Estrada, Alejandro D., Vargas, Juan A., Rubio-Rivas, Manuel, Laureiro, Jaime, Fernández-Bermúdez, Daniel, Buonaiuto, Verónica A., Larriva, Antonio P. Arenas de, Pascual-Pérez, María de los Reyes, Alcalá-Pedrajas, José N., Ruiz, Ane Labirua-Iturburu, Hernández-Milián, Almudena, Mazo, Marta Gómez del, Antequera, Beatriz, Mella-Pérez, Carmen, Navas-Alcántara, María de la Sierra, Soto-Delgado, Juan F., Gámez-Mancera, Rosa M., Sardiña-González, Cristina, Meijide-Míguez, Héctor, Ramos-Rincón, José M., Gómez-Huelgas, Ricardo, Network, on behalf of the SEMI-COVID-19 Network on behalf of the SEMI-COVID-19, [Muñoz-Gómez,A] Internal Medicine Department, Hospital de Parla, Madrid, Spain. [Fernández-Cruz,A] Infectious Diseases Unit, Internal Medicine Department, Hospital Universitario Puerta de Hierro-Majadahonda, Instituto de Investigación Sanitaria Puerta de Hierro—Segovia de Arana, Madrid, Spain. [Lavilla-Olleros,C, Ausín-García,C, Bendala-Estrada,AD] Internal Medicine Department, Hospital General Universitario Gregorio Marañón, Madrid, Spain. [Giner-Galvañ,V, Wikman,P] Internal Medicine Department, Hospital Clínico Universitario de Sant Joan d’Alacant, Fundación para el Fomento de la Investigación Sanitaria y Biomédica en la Comunidad Valenciana (FISABIO), Alicante, Spain. [Vargas,JA] Internal Medicine Department, Hospital Universitario Puerta de Hierro-Majadahonda, Instituto de Investigación Sanitaria Puerta de Hierro—Segovia de Arana, Madrid, Spain. [Rubio-Rivas,M] Department of Internal Medicine, Bellvitge University Hospital, L’Hospitalet de Llobregat, Barcelona, Spain. [Laureiro,J] Doce de Octubre University Hospital, Madrid, Spain. [Fernández-Bermúdez,D] Internal Medicine Department, Costa del Sol Hospital, Marbella, Spain. [Buonaiuto,VA, and Gómez-Huelgas R] Internal Medicine Department, Regional University Hospital of Málaga, Biomedical Research Institute of Málaga (IBIMA), University of Málaga (UMA), Málaga, Spain. [Arenas de Larriva,AP] Lipids and Atherosclerosis Unit, Department of Internal Medicine, Maimonides Biomedical Research Institute of Córdoba (IMIBIC), Reina Sofia University Hospital, University of Córdoba, Córdoba, Spain. [Arenas de Larriva,AP] CIBER Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III (ISCIII), Madrid, Spain. [Pascual-Pérez,MLR] Internal Medicine Department, University General Hospital of Elda, Alicante, Spain. [Alcalá-Pedrajas,JN] Internal Medicine Department, Pozoblanco Regional Hospital, Córdoba, Spain. [Labirua-Iturburu Ruiz,A] Santa Marina Hospital, Bilbao, Spain. [Hernández-Milián,A] Internal Medicine Department, Son Llàtzer University Hospital, Palma de Mallorca, Spain. [Gómez Del Mazo,M] Internal Medicine Department, San Pedro Hospital, Logroño, Spain. [Antequera,B] Internal Medicine Department, Sagunto Hospital, Valencia, Spain. [Mella-Pérez,C] Universitary Hospital Complex of Ferrol, A Coruña, Spain. [Navas-Alcántara,MS] Internal Medicine Department, Infanta Margarita Hospital, Cabra, Córdoba, Spain. [Soto-Delgado,JF] Internal Medicine Department, University Hospital of Salamanca, Salamanca, Spain. [Gámez-Mancera,RM] Internal Medicine Department, University Hospital Virgen del Rocío, Sevilla, Spain. [Sardiña-González,C] Internal Medicine Department, Monforte de Lemos Public Hospital, Lugo, Spain. [Meijide-Míguez,H] Internal Medicine Department, Quironsalud Hospital, A Coruña, Spain. [Ramos-Rincón,JM] Department of Clinical Medicine, Miguel Hernandez University of Elche, Alicante, Spain.

Subjects
medicine.medical_specialty, ARDS, Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Case-Control Studies::Retrospective Studies [Medical Subject Headings], medicine.medical_treatment, Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Confidence Intervals [Medical Subject Headings], Article, Steroid, corticosteroids, Estudios retrospectivos, Diseases::Respiratory Tract Diseases::Respiration Disorders::Respiratory Insufficiency [Medical Subject Headings], Internal medicine, medicine, Mortalitat, Mortality, Glucocorticoides, Corticoesteroides, Health Care::Health Care Facilities, Manpower, and Services::Health Facilities::Hospitals [Medical Subject Headings], Chemicals and Drugs::Polycyclic Compounds::Steroids [Medical Subject Headings], business.industry, SARS-CoV-2, COVID-19, Retrospective cohort study, General Medicine, medicine.disease, mortality, Diseases::Virus Diseases::RNA Virus Infections::Nidovirales Infections::Coronaviridae Infections::Coronavirus Infections [Medical Subject Headings], Confidence interval, Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Probability::Propensity Score [Medical Subject Headings], Cortisone, body regions, Pneumonia, Chemicals and Drugs::Hormones, Hormone Substitutes, and Hormone Antagonists::Hormones::Adrenal Cortex Hormones::Glucocorticoids [Medical Subject Headings], Respiratory failure, Cortisona, Mortalidad, Propensity score matching, Diseases::Respiratory Tract Diseases::Respiration Disorders::Respiratory Distress Syndrome, Adult [Medical Subject Headings], Medicine, Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Data Collection::Vital Statistics::Mortality::Hospital Mortality [Medical Subject Headings], business, Glucocorticoid, medicine.drug
Abstract

We aimed to determine the impact of steroid use in COVID-19 in-hospital mortality, in a retrospective cohort study of the SEMICOVID19 database of admitted patients with SARS-CoV-2 laboratory-confirmed pneumonia from 131 Spanish hospitals. Patients treated with corticosteroids were compared to patients not treated with corticosteroids, and adjusted using a propensity-score for steroid treatment. From March–July 2020, 5.262 (35.26%) were treated with corticosteroids and 9.659 (64.73%) were not. In-hospital mortality overall was 20.50%, it was higher in patients treated with corticosteroids than in controls (28.5% versus 16.2%, OR 2.068 [95% confidence interval, 1.908 to 2.242], p = 0.0001), however, when adjusting by occurrence of ARDS, mortality was significantly lower in the steroid group (43.4% versus 57.6%, OR 0.564 [95% confidence interval, 0.503 to 0.633], p = 0.0001). Moreover, the greater the respiratory failure, the greater the impact on mortality of the steroid treatment. When adjusting these results including the propensity score as a covariate, in-hospital mortality remained significantly lower in the steroid group (OR 0.774 [0.660 to 0.907], p = 0.002). Steroid treatment reduced mortality by 24% relative to no steroid treatment (RRR 0.24). These results support the use of glucocorticoids in COVID-19 in this subgroup of patients.

Published
2021
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7. Lo que puede esconder una ciatalgia

Author

Sardiña González, Cristina, López Reboiro, Manuel Lorenzo, Sardiña González, Cristina, and López Reboiro, Manuel Lorenzo

Published
2019

10. COVID 19 comprehensive management in a regional hospital of Northwestern Spain.

Author

Sardiña-González C, López-Reboiro ML, Suárez-Fuentetaja R, Castro-Conde BA, Álvarez-Asensio E, and López-Castro J

Subjects
Aged, Aged, 80 and over, COVID-19, COVID-19 Testing, Coronavirus Infections diagnosis, Coronavirus Infections epidemiology, Female, Humans, Incidence, Length of Stay statistics & numerical data, Male, Middle Aged, Pandemics, Pneumonia, Viral diagnosis, Pneumonia, Viral epidemiology, Polymerase Chain Reaction, Respiration, Artificial statistics & numerical data, Spain, Clinical Laboratory Techniques, Contact Tracing, Coronavirus Infections therapy, Hospitalization, Pneumonia, Viral therapy
Abstract

Introduction: The COVID-19 pandemic has brought about a paradigm shift in healthcare., Objective: To evaluate the utility of a strategy to comprehensively address the pandemic in a health area that covers 42,000 people., Method: Between March 10 and May 15, 2020, the COVID Unit was created in the corresponding regional hospital, and an independent circuit was established for the diagnosis and management of patients with suspected or confirmed COVID-19; social health centers were monitored with PCR testing., Results: Eighteen COVID-19-positive patients (age 72.9 ± 13.2 years) were admitted, out of which 66% were males. All these patients had pneumonia and 67% had respiratory distress syndrome; no one required mechanical ventilation. Mean hospital stay was 9.4 ± 5.3 days, and mortality, 11%. PCR tests were applied to all hospital residents (n = 827) and workers (n = 519), 1,044 phone calls were made and 36 hospital admissions were avoided. Only 50 patients required close follow-up, out of which four (0.48%) were positive for COVID-19., Conclusion: Clinical monitoring at the hospital and social health centers showed that patient profile was like that documented in the literature and that the incidence of COVID-19 was low in social health centers., (Copyright: © 2020 Permanyer.)

Published
2020
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