201 results on '"Sangfelt, Olle"'
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2. FBXL12 degrades FANCD2 to regulate replication recovery and promote cancer cell survival under conditions of replication stress
3. FBXO44 promotes DNA replication-coupled repetitive element silencing in cancer cells
4. Ex vivo assessment of targeted therapies in a rare metastatic epithelial–myoepithelial carcinoma
5. PTENP1-AS contributes to BRAF inhibitor resistance and is associated with adverse clinical outcome in stage III melanoma
6. Single cell characterization of B-lymphoid differentiation and leukemic cell states during chemotherapy in ETV6-RUNX1-positive pediatric leukemia identifies drug-targetable transcription factor activities
7. K63-linked ubiquitylation induces global sequestration of mitochondria
8. Mechanistic Study of Wee1 Kinase Inhibition with AZD1775 Exposes Drug Targetable Vulnerabilities in Acute B-Lymphoblastic Leukemia
9. FBW7 suppression leads to SOX9 stabilization and increased malignancy in medulloblastoma
10. Dormant SOX9-Positive Cells Facilitate MYC-Driven Recurrence of Medulloblastoma
11. RETRACTED: A FBXO7/EYA2-SCFFBXW7 axis promotes AXL-mediated maintenance of mesenchymal and immune evasion phenotypes of cancer cells
12. Control of Iron Homeostasis by an Iron-Regulated Ubiquitin Ligase
13. Dormant SOX9-Positive Cells Facilitate MYC-Driven Recurrence of Medulloblastoma
14. A FBXO7/EYA2-SCFFBXW7 axis promotes AXL-mediated maintenance of mesenchymal and immune evasion phenotypes of cancer cells
15. TMOD-25. LATENT SOX9-POSITIVE CELLS BEHIND MYC-DRIVEN MEDULLOBLASTOMA RELAPSE
16. Ablation of Key Oncogenic Pathways by RITA-Reactivated p53 Is Required for Efficient Apoptosis
17. Ex vivo analysis of DNA repair targeting in extreme rare cutaneous apocrine sweat gland carcinoma
18. CDK-mediated activation of the SCFFBXO28 ubiquitin ligase promotes MYC-driven transcription and tumourigenesis and predicts poor survival in breast cancer
19. Mechanisms of Interferon-alpha induced apoptosis in malignant cells
20. Identification and characterization of two novel human mitochondrial elongation factor genes, hEFG2 and hEFG1, phylogenetically conserved through evolution
21. Human F-box protein hCdc4 targets cyclin E for proteolysis and is mutated in a breast cancer cell line
22. Ubiquitylation of Cyclin E Requires the Sequential Function of SCF Complexes Containing Distinct hCdc4 Isoforms
23. Molecular mechanisms underlying interferon-α-induced G0/G1 arrest: CKI-mediated regulation of G1 Cdk-complexes and activation of pocket proteins
24. MBRS-10. QUIESCENT SOX9-POSITIVE CELLS BEHIND MYC DRIVEN MEDULLOBLASTOMA RECURRENCE
25. Abstract 2371: FBXL12 modulates Fanconi anaemia-BRCA signaling under conditions of oncogene-induced replication stress
26. PTEN and DNA-PK determine sensitivity and recovery in response to WEE1 inhibition in human breast cancer
27. Involvement of the Ink4 proteins p16 and p15 in T-lymphocyte senescence
28. Induction of Cip/Kip and Ink4 cyclin dependent kinase inhibitors by interferon-α in hematopoietic cell lines
29. Characterization of a novel B-CLL candidate gene – DLEU7 – located in the 13q14 tumor suppressor locus
30. Interferon-alpha inhibits Stat5 DNA-binding in IL-2 stimulated primary T-lymphocytes
31. MEDU-26. LATENT SOX9-POSITIVE CELLS RESPONSIBLE FOR MYC-DRIVEN MEDULLOBLASTOMA RECURRENCE
32. Ablation of Key Oncogenic Pathways by RITA-Reactivated p53 Is Required for Efficient Apoptosis
33. Comparative Sequence Analysis of a Region on Human Chromosome 13q14, Frequently Deleted in B-Cell Chronic Lymphocytic Leukemia, and Its Homologous Region on Mouse Chromosome 14
34. Interferon α down-regulates telomerase reverse transcriptase and telomerase activity in human malignant and nonmalignant hematopoietic cells
35. TMOD-35. CAN RARE SOX9-POSITIVE CELLS INCITE MYC-DRIVEN MEDULLOBLASTOMA RECURRENCE?
36. TMOD-31. RARE SOX9+ CELLS BEHIND MYC-DRIVEN MEDULLOBLASTOMA RECURRENCE
37. Targeting SOX9 for degradation to inhibit chemoresistance, metastatic spread, and recurrence
38. FBW7 suppression leads to SOX9 stabilization and increased malignancy in medulloblastoma
39. In beta-actin knockouts, epigenetic reprogramming and rDNA transcription inactivation lead to growth and proliferation defects
40. Targeting SOX9 for degradation to inhibit chemoresistance, metastatic spread, and recurrence
41. CDK-mediated activation of the SCF(FBXO) (28) ubiquitin ligase promotes MYC-driven transcription and tumourigenesis and predicts poor survival in breast cancer
42. CDK ‐mediated activation of theSCF FBXO28 ubiquitin ligase promotes MYC ‐driven transcription and tumourigenesis and predicts poor survival in breast cancer
43. The RBCC Gene RFP2 (Leu5) Encodes a Novel Transmembrane E3 Ubiquitin Ligase Involved in ERAD
44. FBXW7/hCDC4 is a general tumor suppressor in human cancer
45. Fbw7α and Fbw7γ Collaborate To Shuttle Cyclin E1 into the Nucleolus for Multiubiquitylation
46. Proteomic screen reveals Fbw7 as a modulator of the NF-κB pathway
47. MiRNA-27a controls FBW7/hCDC4-dependent cyclin E degradation and cell cycle progression
48. Inactivation of FBXW7/hCDC4-β expression by promoter hypermethylation is associated with favorable prognosis in primary breast cancer
49. RFP2 Modulates 20S Proteasome Activity, NF Kappa B Activation, and Tumor Cell Growth in Multiple Myeloma.
50. FBXW7/hCDC4 Is a General Tumor Suppressor in Human Cancer
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