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38 results on '"Saleh, M.M."'

9. EP08.02-106 KEAP1/NFE2L2 Transcriptomic Signature Predicts Survival in Advanced Stage NSCLC Patients Without Actionable Driver Mutations

Author

Scheffler, M., primary, Dugan, M., additional, Saleh, M.M., additional, Koleczko, S., additional, Brägelmann, J., additional, Arolt, C., additional, Nogova, L., additional, Riedel, R., additional, Michels, S., additional, Eisert, A., additional, Fischer, R., additional, Scharpenseel, H., additional, Weber, J.-P., additional, Scheel, A.H., additional, Merkelbach-Bruse, S., additional, Büttner, R., additional, Lafleur, F., additional, Wild, R., additional, Catanzariti, L., additional, Hillmer, A.M., additional, and Wolf, J., additional

Published
2022
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15. Spectrum of mutations underlying Propionic acidemia and further insight into a genotype-phenotype correlation for the common mutation in Saudi Arabia

Author

Al-Hamed, Mohamed H., primary, Imtiaz, Faiqa, additional, Al-Hassnan, Zuhair, additional, Al-Owain, Mohammed, additional, Al-Zaidan, Hamad, additional, Alamoudi, Mohamed S., additional, Faqeih, Eissa, additional, Alfadhel, Majid, additional, Al-Asmari, Ali, additional, Saleh, M.M., additional, Al Mutairi, Fuad, additional, Moghrabi, Nabil, additional, and AlSayed, Moeenaldeen, additional

Published
2019
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16. The Ability of Women to Overcome Household Food Insecurity: Social Support & Social Networks

Author

Mph Saleh M.M. Rahman, Mitwe Musingo, Coumba Mar Gadio, P. Qasimah Boston, Mph, DrPH, C. Perry Brown, Msph, DrPH, and Ivette A López

Subjects
medicine.medical_specialty, Health (social science), Social network, business.industry, Health Policy, Public health, Public Health, Environmental and Occupational Health, Medicine (miscellaneous), Qualitative property, medicine.disease, Health Professions (miscellaneous), Obesity, Mental health, Social support, Low birth weight, medicine, Marital status, medicine.symptom, Socioeconomics, Psychology, business
Abstract

Food insecurity is a daily reality for millions globally and persists in rural northern Ghana. Being more a problem in resource poor countries, it challenges the wellbeing of children, adults, families and communities by creating public health problems including; low birth weight babies, mental health conditions, diabetes and obesity. This research examined associations between social networks and social support and women's ability to overcome household food insecurity. A two-phase mixed method quantitative and qualitative data collection technique was applied. A 24-item instrument was developed, pilot tested, validated and administered among women responsible for food preparation in the household (n=241). Measures of household food insecurity, socio-demographic, social network, and perceived social support were constructed and analyzed using SPSS 19®. Women in northern rural Ghana who were married, with higher social supports and social networks were more likely to experience low household food insecurity. Of 241 women, 88% were married, 39% had co-wives, 80% did not have formal education, the average age was 40 years and the average number of adults per household was 7. Correlation analysis and logistic regression models revealed social networks, perceived social support, marital status and years living in the village were significantly associated to the experience of low household food insecurity.

Published
2013

18. Global, regional, and national disability-adjusted life-years (DALYs) for 333 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990-2016: A systematic analysis for the Global Burden of Disease Study 2016.

Author

Kaul A., Bhutta Z.A., Hailu G.B., Hamadeh R.R., Hamidi S., Hammami M., Handal A.J., Hankey G.J., Hao Y., Harb H.L., Hareri H.A., Haro J.M., Harun K.M., Harvey J., Hassanvand M.S., Havmoeller R., Hay R.J., Hedayati M.T., Hendrie D., Henry N.J., Heredia-Pi I.B., Heydarpour P., Hoek H.W., Hofman H.J., Horino M., Horita N., Hosgood H.D., Hostiuc S., Hotez P.J., Hoy D.G., Htet A.S., Hu G., Huang J.J., Huynh C., Iburg K.M., Igumbor E.U., Ikeda C., Irvine C.M.S., Jacobsen K.H., Jahanmehr N., Jakovljevic M.B., James P., Jassal S.K., Javanbakht M., Jayaraman S.P., Jeemon P., Jensen P.N., Jha V., Jiang G., John D., Johnson C.O., Johnson S.C., Jonas J.B., Jurisson M., Kabir Z., Kadel R., Kahsay A., Kamal R., Kar C., Karam N.E., Karch A., Karema C.K., Karimi S.M., Karimkhani C., Kasaeian A., Kassa G.M., Kassebaum N.J., Kassaw N.A., Kastor A., Katikireddi S.V., Kawakami N., Keiyoro P.N., Kemmer L., Kengne A.P., Keren A., Kesavachandran C.N., Khader Y.S., Khalil I.A., Khan E.A., Khang Y.-H., Khoja A.T., Khosravi A., Khubchandani J., Kieling C., Kim Y.J., Kim D., Kimokoti R.W., Kinfu Y., Kisa A., Kissimova-Skarbek K.A., Kissoon N., Kivimaki M., Knudsen A.K., Kokubo Y., Kolte D., Kopec J.A., Kosen S., Kotsakis G.A., Koul P.A., Koyanagi A., Kravchenko M., Krohn K.J., Defo B.K., Bicer B.K., Kumar G.A., Kumar P., Kyu H.H., Lager A.C.J., Lal D.K., Lalloo R., Lallukka T., Lambert N., Lan Q., Lansingh V.C., Larsson A., Leasher J.L., Lee P.H., Leigh J., Leshargie C.T., Leung J., Leung R., Levi M., Li Y., Liang X., Liben M.L., Lim S.S., Linn S., Liu A., Liu P.Y., Liu S., Liu Y., Lodha R., Logroscino G., Looker K.J., Lopez A.D., Lorkowski S., Lotufo P.A., Lozano R., Lucas T.C.D., Lunevicius R., Lyons R.A., Macarayan E.R.K., Maddison E.R., Magdy Abd El Razek H., Magdy Abd El Razek M., Magis-Rodriguez C., Mahdavi M., Majdan M., Majdzadeh R., Majeed A., Malekzadeh R., Malhotra R., Malta D.C., Mamun A.A., Manguerra H., Manhertz T., Mantovani L.G., Mapoma C.C., March L.M., Marczak L.B., Martinez-Raga J., Martins P.H.V., Martins-Melo F.R., Martopullo I., Marz W., Mathur M.R., Mazidi M., McAlinden C., McGaughey M., McGrath J.J., McKee M., Mehata S., Meier T., Meles K.G., Memiah P., Memish Z.A., Mendoza W., Mengesha M.M., Mengistie M.A., Mengistu D.T., Mensah G.A., Meretoja A., Meretoja T.J., Mezgebe H.B., Micha R., Millear A., Miller T.R., Minnig S., Mirarefn M., Mirrakhimov E.M., Misganaw A., Mishra S.R., Mitchell P.B., Mohammad K.A., Mohammadi A., Mohammed S., Mohammed K.E., Mohammed M.S.K., Mohan M.B.V., Mokdad A.H., Mollenkopf S.K., Monasta L., Montanez Hernandez J.C., Montico M., Moradi-Lakeh M., Moraga P., Morawska L., Mori R., Morrison S.D., Moses M., Mountjoy-Venning C., Mruts K.B., Mueller U.O., Muller K., Mudoch M.E., Murthy S., Murthy G.V.S., Musa K.I., Nachega J.B., Nagel G., Naghavi M., Naheed A., Naidoo K.S., Nangia V., Nasher J.T., Natarajan G., Negasa D.E., Negoi I., Negoi R.I., Newton C.R., Ngunjiri J.W., Nguyen C.T., Nguyen Q.L., Nguyen G., Nguyen T.H., Nguyen M., Nichols E., Ningrum D.N.A., Nong V.M., Norheim O.F., Norrving B., Noubiap J.J.N., Nyandwi A., Obermeyer C.M., O'Donnell M.J., Ogbo F.A., Oh I.-H., Okoro A., Oladimeji O., Olagunju A.T., Olagunju T.O., Olsen H.E., Olusanya B.O., Olusanya J.O., Ong K., Opio J.N., Oren E., Ortiz A., Osborne R.H., Osgood-Zimmerman A., Osman M., Ota E., Owolabi M.O., Pa M., Pacella R.E., Panda B.K., Pandian J.D., Papachristou C., Park E.-K., Parry C.D., Parsaeian M., Patil S.T., Patten S.B., Patton G.C., Paudel D., Paulson K., Pearce N., Pereira D.M., Perez K.M., Perico N., Pesudovs K., Peterson C.B., Petri W.A., Petzold M., Phillips M.R., Phipps G., Pigott D.M., Pillay J.D., Pinho C., Piradov M.A., Plass D., Pletcher M.A., Popova S., Poulton R.G., Pourmalek F., Prabhakaran D., Prasad N., Purcell C., Purwar M., Qorbani M., Rabiee R.H.S., Radfar A., Rafay A., Rahimi K., Rahimi-Movaghar A., Rahimi-Movaghar V., Rahman M., Rahman M.A., Rahman M.H.U., Rai R.K., Rajsic S., Ram U., Ranabhat C.L., Rangaswamy T., Rankin Z., Rao P.V., Rao P.C., Rawaf S., Ray S.E., Reiner R.C., Reinig N., Reitsma M., Remuzzi G., Renzaho A.M.N., Resnikof S., Rezaei S., Ribeiro A.L., Roba H.S., Robinson S.R., Rojas-Rueda D., Rokni M.B., Ronfani L., Roshandel G., Roth G.A., Rothenbacher D., Roy A., Rubagotti E., Ruhago G.M., Saadat S., Safdarian M., Safri S., Sagar R., Sahathevan R., Sahraian M.A., Salama J., Saleh M.M., Salomon J.A., Salvi S.S., Samy A.M., Sanabria J.R., Sanchez-Nino M.D., Santomauro D., Santos J.V., Santos I.S., Santric Milicevic M.M., Sartorius B., Satpathy M., Sawhney M., Saxena S., Schelonka K., Schmidt M.I., Schneider I.J.C., Schottker B., Schutte A.E., Schwebel D.C., Schwendicke F., Seedat S., Sepanlou S.G., Servan-Mori E.E., Shaheen A., Shaikh M.A., Shamsipour M., Shariful Islam S.M., Sharma R., Sharma J., She J., Shi P., Shibuya K., Shields C., Shiferaw M.S., Shigematsu M., Shiri R., Shirkoohi R., Shirude S., Shishani K., Shoman H., Siabani S., Sibai A.M., Sigfusdottir I.D., Silberberg D.H., Silva J.P., Silva D.A.S., Silveira D.G.A., Singh J.A., Singh V., Singh O.P., Singh N.P., Sinha D.N., Skiadaresi E., Skirbekk V., Slepak E.L., Smith D.L., Smith M., Sobaih B.H.A., Sobngwi E., Soljak M., Sorensen R.J.D., Sousa T.C.M., Sposato L.A., Sreeramareddy C.T., Srinivasan V., Stanaway J.D., Stathopoulou V., Steel N., Stein D.J., Steiner C., Steinke S., Stokes M.A., Stovner L.J., Strub B., Subart M., Sufyan M.B., Abdulkader R.S., Sunguya B.F., Sur P.J., Swaminathan S., Sykes B.L., Sylte D., Szoeke C.E.I., Tabares-Seisdedos R., Tadakamadla S.K., Tafere G.R., Takala J.S., Tandon N., Tanne D., Tarekegn Y.L., Tavakkoli M., Taveira N., Taylor H.R., Tegegne T.K., Tehrani-Banihashemi A., Tekelab T., Temam Shifa G., Terkawi A.S., Tesfaye D.J., Tesssema B., Thakur J.S., Thamsuwan O., Theadom A.M., Theis A.M., Thomas K.E., Thomas N., Thompson R., Tobe-Gai R., Tobollik M., Tonelli M., Topor-Madry R., Tortajada M., Touvier M., Traebert J., Tran B.X., Troeger C., Truelsen T., Tsoi D., Tuzcu E.M., Tymeson H., Tyrovolas S., Ukwaja K.N., Undurraga E.A., Uneke C.J., Updike R., Uthman O.A., Uzochukwu B.S.C., Van Boven J.F.M., Varughese S., Vasankari T., Veerman L.J., Venkatesh S., Venketasubramanian N., Vidavalur R., Vijayakumar L., Violante F.S., Vishnu A., Vladimirov S.K., Vlassov V.V., Vollset S.E., Vos T., Wadilo F., Wakayo T., Wallin M.T., Wang Y.-P., Weichenthal S., Weiderpass E., Weintraub R.G., Weiss D.J., Werdecker A., Westerman R., Whiteford H.A., Wijeratne T., Williams H.C., Wiysonge C.S., Woldeyes B.G., Wolfe C.D.A., Woodbrook R., Woolf A.D., Workicho A., Xavier D., Xu G., Yadgir S., Yaghoubi M., Yakob B., Yan L.L., Yano Y., Ye P., Yihdego M.G., Yimam H.H., Yip P., Yonemoto N., Yoon S.-J., Yotebieng M., Younis M.Z., Yu C., Zaidi Z., Zaki M.E.S., Zegeye E.A., Zenebe Z.M., Zhang X., Zheng Y., Zhou M., Zipkin B., Zodpey S., Zoeckler L., Zuhlke L.J., Murray C.J.L., Adedji I.A., Murdoch M.E., Bryane C.E.G., De Courten B., Thrift A.G., Biadgilign S., Hay S.I., Abajobir A.A., Abate K.H., Abbafati C., Abbas K.M., Abd-Allah F., Abdulle A.M., Abebo T.A., Abera S.F., Aboyans V., Abu-Raddad L.J., Ackerman I.N., Adedeji I.A., Adetokunboh O., Afshin A., Aggarwal R., Agrawal S., Agrawal A., Kiadaliri A.A., Ahmed M.B., Aichour A.N., Aichour I., Aichour M.T.E., Aiyar S., Akinyemiju T.F., Akseer N., Al Lami F.H., Alahdab F., Al-Aly Z., Alam K., Alam N., Alam T., Alasfoor D., Alene K.A., Ali R., Alizadeh-Navaei R., Alkaabi J.M., Alkerwi A., Alla F., Allebeck P., Allen C., Al-Maskari F., Almazroa M.A., Al-Raddadi R., Alsharif U., Alsowaidi S., Althouse B.M., Altirkawi K.A., Alvis-Guzman N., Amare A.T., Amini E., Ammar W., Amoako Y.A., Ansha M.G., Antonio C.A.T., Anwari P., Arnlov J., Arora M., Artaman A., Aryal K.K., Asgedom S.W., Atey T.M., Atnafu N.T., Avila-Burgos L., Arthur Avokpaho E.F.G., Awasthi A., Awasthi S., Quintanilla B.P.A., Azarpazhooh M.R., Azzopardi P., Babalola T.K., Bacha U., Badawi A., Balakrishnan K., Bannick M.S., Barac A., Barker-Collo S.L., Barnighausen T., Barquera S., Barrero L.H., Basu S., Battista R., Battle K.E., Baune B.T., Bazargan-Hejazi S., Beardsley J., Bedi N., Bejot Y., Bekele B.B., Bell M.L., Bennett D.A., Bennett J.R., Bensenor I.M., Benson J., Berhane A., Berhe D.F., Bernabe E., Betsu B.D., Beuran M., Beyene A.S., Bhansali A., Bhatt S., Bienhof K., Bikbov B., Birungi C., Biryukov S., Bisanzio D., Bizuayehu H.M., Blyth F.M., Boneya D.J., Bose D., Bou-Orm I.R., Bourne R.R.A., Brainin M., Brayne C.E.G., Brazinova A., Breitborde N.J.K., Briant P.S., Britton G., Brugha T.S., Buchbinder R., Bulto L.N.B., Bumgarner B., Butt Z.A., Cahuana-Hurtado L., Cameron E., Campos-Nonato I.R., Carabin H., Cardenas R., Carpenter D.O., Carrero J.J., Carter A., Carvalho F., Casey D., Castaneda-Orjuela C.A., Rivas J.C., Castle C.D., Catala-Lopez F., Chang J.-C., Charlson F.J., Chaturvedi P., Chen H., Chibalabala M., Chibueze C.E., Chisumpa V.H., Chitheer A.A., Chowdhury R., Christopher D.J., Ciobanu L.G., Cirillo M., Colombara D., Cooper L.T., Cooper C., Cortesi P.A., Cortinovis M., Criqui M.H., Cromwell E.A., Cross M., Crump J.A., Dadi A.F., Dalal K., Damasceno A., Dandona L., Dandona R., Das Neves J., Davitoiu D.V., Davletov K., De Leo D., De Steur H., Degenhardt L., Deiparine S., Dellavalle R.P., Deribe K., Deribew A., Das Jarlais D.C., Dey S., Dharmaratne S.D., Dhillon P.K., Dicker D., Djalalinia S., Do H.P., Dokova K., Doku D.T., Dorsey E.R., Dos Santos K.P.B., Driscoll T.R., Dubey M., Duncan B.B., Ebel B.E., Echko M., El-Khatib Z.Z., Enayati A., Endries A.Y., Ermakov S.P., Erskine H.E., Eshetie S., Eshrati B., Esteghamati A., Estep K., Fanuel F.B.B., Farag T., Farinha C.S.E.S., Faro A., Farzadfar F., Fazeli M.S., Feigin V.L., Feigl A.B., Fereshtehnejad S.-M., Fernandes J.C., Ferrari A.J., Feyissa T.R., Filip I., Fischer F., Fitzmaurice C., Flaxman A.D., Foigt N., Foreman K.J., Franklin R.C., Frostad J.J., Fullman N., Furst T., Furtado J.M., Futran N.D., Gakidou E., Garcia-Basteiro A.L., Gebre T., Gebregergs G.B., Gebrehiwot T.T., Geleijnse J.M., Geleto A., Gemechu B.L., Gesesew H.A., Gething P.W., Ghajar A., Gibney K.B., Gillum R.F., Ginawi I.A.M., Gishu M.D., Giussani G., Godwin W.W., Goel K., Goenka S., Goldberg E.M., Gona P.N., Goodridge A., Gopalani S.V., Gosselin R.A., Gotay C.C., Goto A., Goulart A.C., Graetz N., Gugnani H.C., Gupta P.C., Gupta T., Gupta V., Gupta R., Gutierrez R.A., Hachinski V., Hafezi-Nejad N., Hailu A.D., Kaul A., Bhutta Z.A., Hailu G.B., Hamadeh R.R., Hamidi S., Hammami M., Handal A.J., Hankey G.J., Hao Y., Harb H.L., Hareri H.A., Haro J.M., Harun K.M., Harvey J., Hassanvand M.S., Havmoeller R., Hay R.J., Hedayati M.T., Hendrie D., Henry N.J., Heredia-Pi I.B., Heydarpour P., Hoek H.W., Hofman H.J., Horino M., Horita N., Hosgood H.D., Hostiuc S., Hotez P.J., Hoy D.G., Htet A.S., Hu G., Huang J.J., Huynh C., Iburg K.M., Igumbor E.U., Ikeda C., Irvine C.M.S., Jacobsen K.H., Jahanmehr N., Jakovljevic M.B., James P., Jassal S.K., Javanbakht M., Jayaraman S.P., Jeemon P., Jensen P.N., Jha V., Jiang G., John D., Johnson C.O., Johnson S.C., Jonas J.B., Jurisson M., Kabir Z., Kadel R., Kahsay A., Kamal R., Kar C., Karam N.E., Karch A., Karema C.K., Karimi S.M., Karimkhani C., Kasaeian A., Kassa G.M., Kassebaum N.J., Kassaw N.A., Kastor A., Katikireddi S.V., Kawakami N., Keiyoro P.N., Kemmer L., Kengne A.P., Keren A., Kesavachandran C.N., Khader Y.S., Khalil I.A., Khan E.A., Khang Y.-H., Khoja A.T., Khosravi A., Khubchandani J., Kieling C., Kim Y.J., Kim D., Kimokoti R.W., Kinfu Y., Kisa A., Kissimova-Skarbek K.A., Kissoon N., Kivimaki M., Knudsen A.K., Kokubo Y., Kolte D., Kopec J.A., Kosen S., Kotsakis G.A., Koul P.A., Koyanagi A., Kravchenko M., Krohn K.J., Defo B.K., Bicer B.K., Kumar G.A., Kumar P., Kyu H.H., Lager A.C.J., Lal D.K., Lalloo R., Lallukka T., Lambert N., Lan Q., Lansingh V.C., Larsson A., Leasher J.L., Lee P.H., Leigh J., Leshargie C.T., Leung J., Leung R., Levi M., Li Y., Liang X., Liben M.L., Lim S.S., Linn S., Liu A., Liu P.Y., Liu S., Liu Y., Lodha R., Logroscino G., Looker K.J., Lopez A.D., Lorkowski S., Lotufo P.A., Lozano R., Lucas T.C.D., Lunevicius R., Lyons R.A., Macarayan E.R.K., Maddison E.R., Magdy Abd El Razek H., Magdy Abd El Razek M., Magis-Rodriguez C., Mahdavi M., Majdan M., Majdzadeh R., Majeed A., Malekzadeh R., Malhotra R., Malta D.C., Mamun A.A., Manguerra H., Manhertz T., Mantovani L.G., Mapoma C.C., March L.M., Marczak L.B., Martinez-Raga J., Martins P.H.V., Martins-Melo F.R., Martopullo I., Marz W., Mathur M.R., Mazidi M., McAlinden C., McGaughey M., McGrath J.J., McKee M., Mehata S., Meier T., Meles K.G., Memiah P., Memish Z.A., Mendoza W., Mengesha M.M., Mengistie M.A., Mengistu D.T., Mensah G.A., Meretoja A., Meretoja T.J., Mezgebe H.B., Micha R., Millear A., Miller T.R., Minnig S., Mirarefn M., Mirrakhimov E.M., Misganaw A., Mishra S.R., Mitchell P.B., Mohammad K.A., Mohammadi A., Mohammed S., Mohammed K.E., Mohammed M.S.K., Mohan M.B.V., Mokdad A.H., Mollenkopf S.K., Monasta L., Montanez Hernandez J.C., Montico M., Moradi-Lakeh M., Moraga P., Morawska L., Mori R., Morrison S.D., Moses M., Mountjoy-Venning C., Mruts K.B., Mueller U.O., Muller K., Mudoch M.E., Murthy S., Murthy G.V.S., Musa K.I., Nachega J.B., Nagel G., Naghavi M., Naheed A., Naidoo K.S., Nangia V., Nasher J.T., Natarajan G., Negasa D.E., Negoi I., Negoi R.I., Newton C.R., Ngunjiri J.W., Nguyen C.T., Nguyen Q.L., Nguyen G., Nguyen T.H., Nguyen M., Nichols E., Ningrum D.N.A., Nong V.M., Norheim O.F., Norrving B., Noubiap J.J.N., Nyandwi A., Obermeyer C.M., O'Donnell M.J., Ogbo F.A., Oh I.-H., Okoro A., Oladimeji O., Olagunju A.T., Olagunju T.O., Olsen H.E., Olusanya B.O., Olusanya J.O., Ong K., Opio J.N., Oren E., Ortiz A., Osborne R.H., Osgood-Zimmerman A., Osman M., Ota E., Owolabi M.O., Pa M., Pacella R.E., Panda B.K., Pandian J.D., Papachristou C., Park E.-K., Parry C.D., Parsaeian M., Patil S.T., Patten S.B., Patton G.C., Paudel D., Paulson K., Pearce N., Pereira D.M., Perez K.M., Perico N., Pesudovs K., Peterson C.B., Petri W.A., Petzold M., Phillips M.R., Phipps G., Pigott D.M., Pillay J.D., Pinho C., Piradov M.A., Plass D., Pletcher M.A., Popova S., Poulton R.G., Pourmalek F., Prabhakaran D., Prasad N., Purcell C., Purwar M., Qorbani M., Rabiee R.H.S., Radfar A., Rafay A., Rahimi K., Rahimi-Movaghar A., Rahimi-Movaghar V., Rahman M., Rahman M.A., Rahman M.H.U., Rai R.K., Rajsic S., Ram U., Ranabhat C.L., Rangaswamy T., Rankin Z., Rao P.V., Rao P.C., Rawaf S., Ray S.E., Reiner R.C., Reinig N., Reitsma M., Remuzzi G., Renzaho A.M.N., Resnikof S., Rezaei S., Ribeiro A.L., Roba H.S., Robinson S.R., Rojas-Rueda D., Rokni M.B., Ronfani L., Roshandel G., Roth G.A., Rothenbacher D., Roy A., Rubagotti E., Ruhago G.M., Saadat S., Safdarian M., Safri S., Sagar R., Sahathevan R., Sahraian M.A., Salama J., Saleh M.M., Salomon J.A., Salvi S.S., Samy A.M., Sanabria J.R., Sanchez-Nino M.D., Santomauro D., Santos J.V., Santos I.S., Santric Milicevic M.M., Sartorius B., Satpathy M., Sawhney M., Saxena S., Schelonka K., Schmidt M.I., Schneider I.J.C., Schottker B., Schutte A.E., Schwebel D.C., Schwendicke F., Seedat S., Sepanlou S.G., Servan-Mori E.E., Shaheen A., Shaikh M.A., Shamsipour M., Shariful Islam S.M., Sharma R., Sharma J., She J., Shi P., Shibuya K., Shields C., Shiferaw M.S., Shigematsu M., Shiri R., Shirkoohi R., Shirude S., Shishani K., Shoman H., Siabani S., Sibai A.M., Sigfusdottir I.D., Silberberg D.H., Silva J.P., Silva D.A.S., Silveira D.G.A., Singh J.A., Singh V., Singh O.P., Singh N.P., Sinha D.N., Skiadaresi E., Skirbekk V., Slepak E.L., Smith D.L., Smith M., Sobaih B.H.A., Sobngwi E., Soljak M., Sorensen R.J.D., Sousa T.C.M., Sposato L.A., Sreeramareddy C.T., Srinivasan V., Stanaway J.D., Stathopoulou V., Steel N., Stein D.J., Steiner C., Steinke S., Stokes M.A., Stovner L.J., Strub B., Subart M., Sufyan M.B., Abdulkader R.S., Sunguya B.F., Sur P.J., Swaminathan S., Sykes B.L., Sylte D., Szoeke C.E.I., Tabares-Seisdedos R., Tadakamadla S.K., Tafere G.R., Takala J.S., Tandon N., Tanne D., Tarekegn Y.L., Tavakkoli M., Taveira N., Taylor H.R., Tegegne T.K., Tehrani-Banihashemi A., Tekelab T., Temam Shifa G., Terkawi A.S., Tesfaye D.J., Tesssema B., Thakur J.S., Thamsuwan O., Theadom A.M., Theis A.M., Thomas K.E., Thomas N., Thompson R., Tobe-Gai R., Tobollik M., Tonelli M., Topor-Madry R., Tortajada M., Touvier M., Traebert J., Tran B.X., Troeger C., Truelsen T., Tsoi D., Tuzcu E.M., Tymeson H., Tyrovolas S., Ukwaja K.N., Undurraga E.A., Uneke C.J., Updike R., Uthman O.A., Uzochukwu B.S.C., Van Boven J.F.M., Varughese S., Vasankari T., Veerman L.J., Venkatesh S., Venketasubramanian N., Vidavalur R., Vijayakumar L., Violante F.S., Vishnu A., Vladimirov S.K., Vlassov V.V., Vollset S.E., Vos T., Wadilo F., Wakayo T., Wallin M.T., Wang Y.-P., Weichenthal S., Weiderpass E., Weintraub R.G., Weiss D.J., Werdecker A., Westerman R., Whiteford H.A., Wijeratne T., Williams H.C., Wiysonge C.S., Woldeyes B.G., Wolfe C.D.A., Woodbrook R., Woolf A.D., Workicho A., Xavier D., Xu G., Yadgir S., Yaghoubi M., Yakob B., Yan L.L., Yano Y., Ye P., Yihdego M.G., Yimam H.H., Yip P., Yonemoto N., Yoon S.-J., Yotebieng M., Younis M.Z., Yu C., Zaidi Z., Zaki M.E.S., Zegeye E.A., Zenebe Z.M., Zhang X., Zheng Y., Zhou M., Zipkin B., Zodpey S., Zoeckler L., Zuhlke L.J., Murray C.J.L., Adedji I.A., Murdoch M.E., Bryane C.E.G., De Courten B., Thrift A.G., Biadgilign S., Hay S.I., Abajobir A.A., Abate K.H., Abbafati C., Abbas K.M., Abd-Allah F., Abdulle A.M., Abebo T.A., Abera S.F., Aboyans V., Abu-Raddad L.J., Ackerman I.N., Adedeji I.A., Adetokunboh O., Afshin A., Aggarwal R., Agrawal S., Agrawal A., Kiadaliri A.A., Ahmed M.B., Aichour A.N., Aichour I., Aichour M.T.E., Aiyar S., Akinyemiju T.F., Akseer N., Al Lami F.H., Alahdab F., Al-Aly Z., Alam K., Alam N., Alam T., Alasfoor D., Alene K.A., Ali R., Alizadeh-Navaei R., Alkaabi J.M., Alkerwi A., Alla F., Allebeck P., Allen C., Al-Maskari F., Almazroa M.A., Al-Raddadi R., Alsharif U., Alsowaidi S., Althouse B.M., Altirkawi K.A., Alvis-Guzman N., Amare A.T., Amini E., Ammar W., Amoako Y.A., Ansha M.G., Antonio C.A.T., Anwari P., Arnlov J., Arora M., Artaman A., Aryal K.K., Asgedom S.W., Atey T.M., Atnafu N.T., Avila-Burgos L., Arthur Avokpaho E.F.G., Awasthi A., Awasthi S., Quintanilla B.P.A., Azarpazhooh M.R., Azzopardi P., Babalola T.K., Bacha U., Badawi A., Balakrishnan K., Bannick M.S., Barac A., Barker-Collo S.L., Barnighausen T., Barquera S., Barrero L.H., Basu S., Battista R., Battle K.E., Baune B.T., Bazargan-Hejazi S., Beardsley J., Bedi N., Bejot Y., Bekele B.B., Bell M.L., Bennett D.A., Bennett J.R., Bensenor I.M., Benson J., Berhane A., Berhe D.F., Bernabe E., Betsu B.D., Beuran M., Beyene A.S., Bhansali A., Bhatt S., Bienhof K., Bikbov B., Birungi C., Biryukov S., Bisanzio D., Bizuayehu H.M., Blyth F.M., Boneya D.J., Bose D., Bou-Orm I.R., Bourne R.R.A., Brainin M., Brayne C.E.G., Brazinova A., Breitborde 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Abstract

Background: Measurement of changes in health across locations is useful to compare and contrast changing epidemiological patterns against health system performance and identify specific needs for resource allocation in research, policy development, and programme decision making. Using the Global Burden of Diseases, Injuries, and Risk Factors Study 2016, we drew from two widely used summary measures to monitor such changes in population health: disability-adjusted life-years (DALYs) and healthy life expectancy (HALE). We used these measures to track trends and benchmark progress compared with expected trends on the basis of the Socio-demographic Index (SDI). Method(s): We used results from the Global Burden of Diseases, Injuries, and Risk Factors Study 2016 for all-cause mortality, cause-specific mortality, and non-fatal disease burden to derive HALE and DALYs by sex for 195 countries and territories from 1990 to 2016. We calculated DALYs by summing years of life lost and years of life lived with disability for each location, age group, sex, and year. We estimated HALE using age-specific death rates and years of life lived with disability per capita. We explored how DALYs and HALE difered from expected trends when compared with the SDI: the geometric mean of income per person, educational attainment in the population older than age 15 years, and total fertility rate. Finding(s): The highest globally observed HALE at birth for both women and men was in Singapore, at 75.2 years (95% uncertainty interval 71.9-78.6) for females and 72.0 years (68.8-75.1) for males. The lowest for females was in the Central African Republic (45.6 years [42.0-49.5]) and for males was in Lesotho (41.5 years [39.0-44.0]). From 1990 to 2016, global HALE increased by an average of 6.24 years (5.97-6.48) for both sexes combined. Global HALE increased by 6.04 years (5.74-6.27) for males and 6.49 years (6.08-6.77) for females, whereas HALE at age 65 years increased by 1.78 years (1.61-1.93) for m

Published
2017

21. Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks, 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015.

Author

Abraham B., Patil S.T., Patten S.B., Wang J., Pereira D.M., Cortinovis M., Giussani G., Perico N., Remuzzi G., Pesudovs K., Phillips M.R., Pillay J.D., Plass D., Tobollik M., Polinder S., Pond C.D., Pope C.A., Prasad N.M., Qorbani M., Radfar A., Rafay A., Rana S.M., Rahman M., Rahman S.U., Rajsic S., Rai R.K., Raju M., Ranganathan K., Refaat A.H., Rehm C.D., Ribeiro A.L., Rojas-Rueda D., Roy A., Satpathy M., Tandon N., Rothenbacher D., Saleh M.M., Sanabria J.R., Sanchez-Riera L., Sanchez-Nino M.D., Sarmiento-Suarez R., Sawhney M., Schmidhuber J., Schneider I.J.C., Schutte A.E., Silva D.A.S., Shahraz S., Shin M., Shaheen A., Shaikh M.A., Sharma R., Shigematsu M., Yoon S., Shishani K., Sigfusdottir I.D., Singh P.K., Silveira D.G.A., Silverberg J.I., Yano Y., Soneji S., Stranges S., Steckling N., Sreeramareddy C.T., Stathopoulou V., Stroumpoulis K., Sunguya B.F., Swaminathan S., Sykes B.L., Tabares-Seisdedos R., Talongwa R.T., Tanne D., Tuzcu E.M., Thakur J., Shaddick G., Thomas M.L., Thrift A.G., Thurston G.D., Thomson A.J., Topor-Madry R., Topouzis F., Towbin J.A., Uthman O.A., Tobe-Gai R., Tsilimparis N., Tsala Z., Tyrovolas S., Ukwaja K.N., van Os J., Vasankari T., Venketasubramanian N., Violante F.S., Waller S.G., Uneke C.J., Wang Y., Weichenthal S., Woolf A.D., Xavier D., Xu G., Yakob B., Yip P., Kesavachandran C.N., Montico M., Ronfani L., Yu C., Zaidi Z., Yonemoto N., Younis M.Z., Wubshet M., Zuhlke L.J., Zaki M.E., Zhu J., Forouzanfar M.H., Afshin A., Alexander L.T., Biryukov S., Brauer M., Cercy K., Charlson F.J., Cohen A.J., Dandona L., Estep K., Ferrari A.J., Frostad J.J., Fullman N., Godwin W.W., Griswold M., Hay S.I., Kyu H.H., Larson H.J., Lim S.S., Liu P.Y., Lopez A.D., Lozano R., Marczak L., Mokdad A.H., Moradi-Lakeh M., Naghavi M., Reitsma M.B., Roth G.A., Sur P.J., Vos T., Wagner J.A., Wang H., Zhao Y., Zhou M., Barber R.M., Bell B., Blore J.D., Casey D.C., Coates M.M., Cooperrider K., Cornaby L., Dicker D., Erskine H.E., Fleming T., Foreman K., Gakidou E., Haagsma J.A., Johnson C.O., Kemmer L., Ku T., Leung J., Masiye F., Millear A., Mirarefin M., Misganaw A., Mullany E., Mumford J.E., Ng M., Olsen H., Rao P., Reinig N., Roman Y., Sandar L., Santomauro D.F., Slepak E.L., Sorensen R.J.D., Thomas B.A., Vollset S.E., Whiteford H.A., Zipkin B., Murray C.J.L., Mock C.N., Anderson B.O., Futran N.D., Anderson H.R., Bhutta Z.A., Nisar M.I., Akseer N., Krueger H., Gotay C.C., Kissoon N., Kopec J.A., Pourmalek F., Burnett R., Abajobir A.A., Knibbs L.D., Veerman J.L., Lalloo R., Scott J.G., Alam N.K.M., Gouda H.N., Guo Y., McGrath J.J., Jeemon P., Dandona R., Goenka S., Kumar G.A., Gething P.W., Bisanzio D., Deribew A., Darby S.C., Ali R., Bennett D.A., Jha V., Kinfu Y., McKee M., Murthy G.V.S., Pearce N., Stockl H., Duan L., Jin Y., Li Y., Liu S., Wang L., Ye P., Liang X., Azzopardi P., Patton G.C., Meretoja A., Alam K., Borschmann R., Colquhoun S.M., Weintraub R.G., Szoeke C.E.I., Ademi Z., Taylor H.R., Wijeratne T., Batis C., Barquera S., Campos-Nonato I.R., Contreras A.G., Cuevas-Nasu L., De V., Gomez-Dantes H., Heredia-Pi I.B., Medina C., Mejia-Rodriguez F., Montanez Hernandez J.C., Razo-Garcia C.A., Rivera J.A., Rodriguez-Ramirez S., Sanchez-Pimienta T.G., Servan-Mori E.E., Shamah T., Mensah G.A., Hoff H.J., Neal B., Driscoll T.R., Kemp A.H., Leigh J., Mekonnen A.B., Bhatt S., Furst T., Piel F.B., Rodriguez A., Hutchings S.J., Majeed A., Soljak M., Salomon J.A., Thorne-Lyman A.L., Ajala O.N., Barnighausen T., Cahill L.E., Ding E.L., Farvid M.S., Khatibzadeh S., Wagner G.R., Shrime M.G., Fitchett J.R.A., Aasvang G.M., Savic M., Abate K.H., Gebrehiwot T.T., Gebremedhin A.T., Abbafati C., Abbas K.M., Abd-Allah F., Abdulle A.M., Abera S.F., Melaku Y.A., Abyu G.Y., Betsu B.D., Hailu G.B., Tekle D.Y., Yalew A.Z., Abu-Raddad L.J., Adebiyi A.O., Adedeji I.A., Adou A.K., Adsuar J.C., Agardh E.E., Rehm J., Badawi A., Popova S., Agarwal A., Ahmad A., Akinyemiju T.F., Schwebel D.C., Singh J.A., Al-Aly Z., Aldhahri S.F., Altirkawi K.A., Terkawi A.S., Aldridge R.W., Tillmann T., Alemu Z.A., Tegegne T.K., Alkerwi A., Alla F., Guillemin F., Allebeck P., Rabiee R.H.S., Fereshtehnejad S.M., Kivipelto M., Carrero J.J., Weiderpass E., Havmoeller R., Sindi S., Alsharif U., Alvarez E., Alvis-Guzman N., Amare A.T., Ciobanu L.G., Taye B.W., Amberbir A., Amegah A.K., Amini H., Karema C.K., Ammar W., Harb H.L., Amrock S.M., Andersen H.H., Antonio C.A.T., Faraon E.J.A., Anwari P., Arnlov J., Larsson A., Artaman A., Asayesh H., Asghar R.J., Assadi R., Atique S., Avokpaho E.F.G.A., Awasthi A., Ayala B.P., Bacha U., Bahit M.C., Balakrishnan K., Barac A., Barker-Collo S.L., del Pozo-Cruz B., Mohammed S., Barregard L., Petzold M., Barrero L.H., Basu S., Del L.C., Bazargan-Hejazi S., Beardsley J., Bedi N., Beghi E., Sheth K.N., Bell M.L., Huang J.J., Bello A.K., Santos I.S., Bensenor I.M., Lotufo P.A., Berhane A., Wolfe C.D., Bernabe E., Roba H.S., Beyene A.S., Hassen T.A., Mesfin Y.M., Bhala N., Bhansali A., 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F., Kasaeian A., Parsaeian M., Esteghamati A., Hafezi-Nejad N., Sheikhbahaei S., Fahimi S., Malekzadeh R., Roshandel G., Sepanlou S.G., Hassanvand M.S., Heydarpour P., Rahimi-Movaghar V., Yaseri M., Farid T.A., Khan A.R., Farinha C.S.E.S., Faro A., Feigin V.L., Fernandes J.G., Fischer F., Foigt N., Shiue I., Fowkes F.G.R., Franklin R.C., Garcia-Basteiro A.L., Geleijnse J.M., Jibat T., Gessner B.D., Tefera W., Giref A.Z., Haile D., Manamo W.A.A., Giroud M., Gishu M.D., Martinez-Raga J., Gomez-Cabrera M.C., Gona P., Goodridge A., Gopalani S.V., Goto A., Inoue M., Gugnani H.C., Gupta R., Gutierrez R.A., Orozco R., Halasa Y.A., Undurraga E.A., Hamadeh R.R., Hamidi S., Handal A.J., Hankey G.J., Hao Y., Harikrishnan S., Haro J.M., Hernandez-Llanes N.F., Hoek H.W., Tura A.K., Horino M., Horita N., Hosgood H.D., Hoy D.G., Hsairi M., Hu G., Husseini A., Huybrechts I., Iburg K.M., Idrisov B.T., Kwan G.F., Ileanu B.V., Pana A., Kawakami N., Shibuya K., Jacobs T.A., Jacobsen K.H., Jahanmehr N., Jakovljevic M.B., Jansen H.A.F., Jassal S.K., Stein M.B., Javanbakht M., Jayaraman S.P., Jayatilleke A.U., Jee S.H., Jonas J.B., Kabir Z., Kalkonde Y., Kamal R., She J., Kan H., Karch A., Karimkhani C., Kaul A., Kazi D.S., Keiyoro P.N., Parry C.D., Kengne A.P., Matzopoulos R., Wiysonge C.S., Stein D.J., Mayosi B.M., Keren A., Khader Y.S., Khan E.A., Khan G., Khang Y.H., Won S., Khera S., Tavakkoli M., Khoja T.A.M., Khubchandani J., Kim C., Kim D., Kimokoti R.W., Kokubo Y., Koul P.A., Koyanagi A., Kravchenko M., Varakin Y.Y., Kuate B., Kuchenbecker R.S., Kucuk B., Kuipers E.J., Lallukka T., Shiri R., Meretoja T.J., Lan Q., Latif A.A., Lawrynowicz A.E.B., Leasher J.L., Levi M., Li X., Liang J., Lloyd B.K., Logroscino G., Lunevicius R., Pope D., Mahdavi M., Malta D.C., Marcenes W., Matsushita K., Nachega J.B., Tran B.X., Meaney P.A., Mehari A., Tedla B.A., Memish Z.A., Mendoza W., Mensink G.B.M., Mhimbira F.A., Miller T.R., Mills E.J., Mohammadi A., Mola G.L.D., Monasta L., Morawska L., Norman R.E., Mori R., Mozaff D., Shi P., Werdecker A., Mueller U.O., Paternina A.J., Westerman R., Seedat S., Naheed A., Nangia V., Nassiri N., Nguyen Q.L., Nkamedjie P.M., Norheim O.F., Norrving B., Nyakarahuka L., Obermeyer C.M., Ogbo F.A., Oh I., Oladimeji O., Sartorius B., Olusanya B.O., Olivares P.R., Olusanya J.O., Opio J.N., Oren E., Ortiz A., Ota E., Mahesh P.A., Park E., Patel T., Abraham B., Patil S.T., Patten S.B., Wang J., Pereira D.M., Cortinovis M., Giussani G., Perico N., Remuzzi G., Pesudovs K., Phillips M.R., Pillay J.D., Plass D., Tobollik M., Polinder S., Pond C.D., Pope C.A., Prasad N.M., Qorbani M., Radfar A., Rafay A., Rana S.M., Rahman M., Rahman S.U., Rajsic S., Rai R.K., Raju M., Ranganathan K., Refaat A.H., Rehm C.D., Ribeiro A.L., Rojas-Rueda D., Roy A., Satpathy M., Tandon N., Rothenbacher D., Saleh M.M., Sanabria J.R., Sanchez-Riera L., Sanchez-Nino M.D., Sarmiento-Suarez R., Sawhney M., Schmidhuber J., Schneider I.J.C., Schutte A.E., Silva D.A.S., Shahraz S., Shin M., Shaheen A., Shaikh M.A., Sharma R., Shigematsu M., Yoon S., Shishani K., Sigfusdottir I.D., Singh P.K., Silveira D.G.A., Silverberg J.I., Yano Y., Soneji S., Stranges S., Steckling N., Sreeramareddy C.T., Stathopoulou V., Stroumpoulis K., Sunguya B.F., Swaminathan S., Sykes B.L., Tabares-Seisdedos R., Talongwa R.T., Tanne D., Tuzcu E.M., Thakur J., Shaddick G., Thomas M.L., Thrift A.G., Thurston G.D., Thomson A.J., Topor-Madry R., Topouzis F., Towbin J.A., Uthman O.A., Tobe-Gai R., Tsilimparis N., Tsala Z., Tyrovolas S., Ukwaja K.N., van Os J., Vasankari T., Venketasubramanian N., Violante F.S., Waller S.G., Uneke C.J., Wang Y., Weichenthal S., Woolf A.D., Xavier D., Xu G., Yakob B., Yip P., Kesavachandran C.N., Montico M., Ronfani L., Yu C., Zaidi Z., Yonemoto N., Younis M.Z., Wubshet M., Zuhlke L.J., Zaki M.E., Zhu J., Forouzanfar M.H., Afshin A., Alexander L.T., Biryukov S., Brauer M., Cercy K., Charlson F.J., Cohen A.J., Dandona L., Estep K., Ferrari A.J., Frostad J.J., Fullman N., Godwin W.W., Griswold M., Hay S.I., Kyu H.H., Larson H.J., Lim S.S., Liu P.Y., Lopez A.D., Lozano R., Marczak L., Mokdad A.H., Moradi-Lakeh M., Naghavi M., Reitsma M.B., Roth G.A., Sur P.J., Vos T., Wagner J.A., Wang H., Zhao Y., Zhou M., Barber R.M., Bell B., Blore J.D., Casey D.C., Coates M.M., Cooperrider K., Cornaby L., Dicker D., Erskine H.E., Fleming T., Foreman K., Gakidou E., Haagsma J.A., Johnson C.O., Kemmer L., Ku T., Leung J., Masiye F., Millear A., Mirarefin M., Misganaw A., Mullany E., Mumford J.E., Ng M., Olsen H., Rao P., Reinig N., Roman Y., Sandar L., Santomauro D.F., Slepak E.L., Sorensen R.J.D., Thomas B.A., Vollset S.E., Whiteford H.A., Zipkin B., Murray C.J.L., Mock C.N., Anderson B.O., Futran N.D., Anderson H.R., Bhutta Z.A., Nisar M.I., Akseer N., Krueger H., Gotay C.C., Kissoon N., Kopec J.A., Pourmalek F., Burnett R., Abajobir A.A., Knibbs L.D., Veerman J.L., Lalloo R., Scott J.G., Alam N.K.M., Gouda H.N., Guo Y., McGrath J.J., Jeemon P., Dandona R., Goenka S., Kumar G.A., Gething P.W., Bisanzio D., Deribew A., Darby S.C., Ali R., Bennett D.A., Jha V., Kinfu Y., McKee M., Murthy G.V.S., Pearce N., Stockl H., Duan L., Jin Y., Li Y., Liu S., Wang L., Ye P., Liang X., Azzopardi P., Patton G.C., Meretoja A., Alam K., Borschmann R., Colquhoun S.M., Weintraub R.G., Szoeke C.E.I., Ademi Z., Taylor H.R., Wijeratne T., Batis C., Barquera S., Campos-Nonato I.R., Contreras A.G., Cuevas-Nasu L., De V., Gomez-Dantes H., Heredia-Pi I.B., Medina C., Mejia-Rodriguez F., Montanez Hernandez J.C., Razo-Garcia C.A., Rivera J.A., Rodriguez-Ramirez S., Sanchez-Pimienta T.G., Servan-Mori E.E., Shamah T., Mensah G.A., Hoff H.J., Neal B., Driscoll T.R., Kemp A.H., Leigh J., Mekonnen A.B., Bhatt S., Furst T., Piel F.B., Rodriguez A., Hutchings S.J., Majeed A., Soljak M., Salomon J.A., Thorne-Lyman A.L., Ajala O.N., Barnighausen T., Cahill L.E., Ding E.L., Farvid M.S., Khatibzadeh S., Wagner G.R., Shrime M.G., Fitchett J.R.A., Aasvang G.M., Savic M., Abate K.H., Gebrehiwot T.T., Gebremedhin A.T., Abbafati C., Abbas K.M., Abd-Allah F., Abdulle A.M., Abera S.F., Melaku Y.A., Abyu G.Y., Betsu B.D., Hailu G.B., Tekle D.Y., Yalew A.Z., Abu-Raddad L.J., Adebiyi A.O., Adedeji I.A., Adou A.K., Adsuar J.C., Agardh E.E., Rehm J., Badawi A., Popova S., Agarwal A., Ahmad A., Akinyemiju T.F., Schwebel D.C., Singh J.A., Al-Aly Z., Aldhahri S.F., Altirkawi K.A., Terkawi A.S., Aldridge R.W., Tillmann T., Alemu Z.A., Tegegne T.K., Alkerwi A., Alla F., Guillemin F., Allebeck P., Rabiee R.H.S., Fereshtehnejad S.M., Kivipelto M., Carrero J.J., Weiderpass E., Havmoeller R., Sindi S., Alsharif U., Alvarez E., Alvis-Guzman N., Amare A.T., Ciobanu L.G., Taye B.W., Amberbir A., Amegah A.K., Amini H., Karema C.K., Ammar W., Harb H.L., Amrock S.M., Andersen H.H., Antonio C.A.T., Faraon E.J.A., Anwari P., Arnlov J., Larsson A., Artaman A., Asayesh H., Asghar R.J., Assadi R., Atique S., Avokpaho E.F.G.A., Awasthi A., Ayala B.P., Bacha U., Bahit M.C., Balakrishnan K., Barac A., Barker-Collo S.L., del Pozo-Cruz B., Mohammed S., Barregard L., Petzold M., Barrero L.H., Basu S., Del L.C., Bazargan-Hejazi S., Beardsley J., Bedi N., Beghi E., Sheth K.N., Bell M.L., Huang J.J., Bello A.K., Santos I.S., Bensenor I.M., Lotufo P.A., Berhane A., Wolfe C.D., Bernabe E., Roba H.S., Beyene A.S., Hassen T.A., Mesfin Y.M., Bhala N., Bhansali A., Biadgilign S., Bikbov B., Bjertness E., Htet A.S., Boufous S., Degenhardt L., Resnikoff S., Calabria B., Bourne R.R.A., Brainin M., Brazinova A., Majdan M., Shen J., Breitborde N.J.K., Brenner H., Schottker B., Broday D.M., Brugha T.S., Brunekreef B., Kromhout H., Butt Z.A., van Donkelaar A., Martin R.V., Cardenas R., Carpenter D.O., Castaneda-Orjuela C.A., Castillo J., Castro R.E., Catala-Lopez F., Chang J., Chiang P.P., Chibalabala M., Chimed-Ochir O., Jiang Y., Takahashi K., Chisumpa V.H., Mapoma C.C., Chitheer A.A., Choi J.J., Christensen H., Christopher D.J., Cooper L.T., Crump J.A., Poulton R.G., Damasceno A., Dargan P.I., das Neves J., Davis A.C., Newton J.N., Steel N., Davletov K., de Castro E.F., De D., Dellavalle R.P., Des D.C., Dharmaratne S.D., Dhillon P.K., Lal D.K., Zodpey S., Diaz-Torne C., Dorsey E.R., Doyle K.E., Dubey M., Rahman M.H.U., Ram U., Singh A., Yadav A.K., Duncan B.B., Kieling C., Schmidt M.I., Elyazar I., Endries A.Y., Ermakov S.P., Eshrati B., Farzadfar F., Kasaeian A., Parsaeian M., Esteghamati A., Hafezi-Nejad N., Sheikhbahaei S., Fahimi S., Malekzadeh R., Roshandel G., Sepanlou S.G., Hassanvand M.S., Heydarpour P., Rahimi-Movaghar V., Yaseri M., Farid T.A., Khan A.R., Farinha C.S.E.S., Faro A., Feigin V.L., Fernandes J.G., Fischer F., Foigt N., Shiue I., Fowkes F.G.R., Franklin R.C., Garcia-Basteiro A.L., Geleijnse J.M., Jibat T., Gessner B.D., Tefera W., Giref A.Z., Haile D., Manamo W.A.A., Giroud M., Gishu M.D., Martinez-Raga J., Gomez-Cabrera M.C., Gona P., Goodridge A., Gopalani S.V., Goto A., Inoue M., Gugnani H.C., Gupta R., Gutierrez R.A., Orozco R., Halasa Y.A., Undurraga E.A., Hamadeh R.R., Hamidi S., Handal A.J., Hankey G.J., Hao Y., Harikrishnan S., Haro J.M., Hernandez-Llanes N.F., Hoek H.W., Tura A.K., Horino M., Horita N., Hosgood H.D., Hoy D.G., Hsairi M., Hu G., Husseini A., Huybrechts I., Iburg K.M., Idrisov B.T., Kwan G.F., Ileanu B.V., Pana A., Kawakami N., Shibuya K., Jacobs T.A., Jacobsen K.H., Jahanmehr N., Jakovljevic M.B., Jansen H.A.F., Jassal S.K., Stein M.B., Javanbakht M., Jayaraman S.P., Jayatilleke A.U., Jee S.H., Jonas J.B., Kabir Z., Kalkonde Y., Kamal R., She J., Kan H., Karch A., Karimkhani C., Kaul A., Kazi D.S., Keiyoro P.N., Parry C.D., Kengne A.P., Matzopoulos R., Wiysonge C.S., Stein D.J., Mayosi B.M., Keren A., Khader Y.S., Khan E.A., Khan G., Khang Y.H., Won S., Khera S., Tavakkoli M., Khoja T.A.M., Khubchandani J., Kim C., Kim D., Kimokoti R.W., Kokubo Y., Koul P.A., Koyanagi A., Kravchenko M., Varakin Y.Y., Kuate B., Kuchenbecker R.S., Kucuk B., Kuipers E.J., Lallukka T., Shiri R., Meretoja T.J., Lan Q., Latif A.A., Lawrynowicz A.E.B., Leasher J.L., Levi M., Li X., Liang J., Lloyd B.K., Logroscino G., Lunevicius R., Pope D., Mahdavi M., Malta D.C., Marcenes W., Matsushita K., Nachega J.B., Tran B.X., Meaney P.A., Mehari A., Tedla B.A., Memish Z.A., Mendoza W., Mensink G.B.M., Mhimbira F.A., Miller T.R., Mills E.J., Mohammadi A., Mola G.L.D., Monasta L., Morawska L., Norman R.E., Mori R., Mozaff D., Shi P., Werdecker A., Mueller U.O., Paternina A.J., Westerman R., Seedat S., Naheed A., Nangia V., Nassiri N., Nguyen Q.L., Nkamedjie P.M., Norheim O.F., Norrving B., Nyakarahuka L., Obermeyer C.M., Ogbo F.A., Oh I., Oladimeji O., Sartorius B., Olusanya B.O., Olivares P.R., Olusanya J.O., Opio J.N., Oren E., Ortiz A., Ota E., Mahesh P.A., Park E., and Patel T.

Abstract

Background The Global Burden of Diseases, Injuries, and Risk Factors Study 2015 provides an up-to-date synthesis of the evidence for risk factor exposure and the attributable burden of disease. By providing national and subnational assessments spanning the past 25 years, this study can inform debates on the importance of addressing risks in context. Methods We used the comparative risk assessment framework developed for previous iterations of the Global Burden of Disease Study to estimate attributable deaths, disability-adjusted life-years (DALYs), and trends in exposure by age group, sex, year, and geography for 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks from 1990 to 2015. This study included 388 risk-outcome pairs that met World Cancer Research Fund-defined criteria for convincing or probable evidence. We extracted relative risk and exposure estimates from randomised controlled trials, cohorts, pooled cohorts, household surveys, census data, satellite data, and other sources. We used statistical models to pool data, adjust for bias, and incorporate covariates. We developed a metric that allows comparisons of exposure across risk factors-the summary exposure value. Using the counterfactual scenario of theoretical minimum risk level, we estimated the portion of deaths and DALYs that could be attributed to a given risk. We decomposed trends in attributable burden into contributions from population growth, population age structure, risk exposure, and risk-deleted cause-specific DALY rates. We characterised risk exposure in relation to a Socio-demographic Index (SDI). Findings Between 1990 and 2015, global exposure to unsafe sanitation, household air pollution, childhood underweight, childhood stunting, and smoking each decreased by more than 25%. Global exposure for several occupational risks, high body-mass index (BMI), and drug use increased by more than 25% over the same period. All risks jointly evaluated in 2015 accou

Published
2016

22. Global, regional, and national life expectancy, all-cause mortality, and cause-specific mortality for 249 causes of death, 1980-2015: a systematic analysis for the Global Burden of Disease Study 2015.

Author

Alhabib S., Lipshultz S.E., Wilkinson J.D., Simard E.P., Liu Y., Phillips M.R., Xiao Q., Lo L., Logroscino G., Lunevicius R., Ma S., Machado V.M., Mackay M.T., Magdy Abd El Razek H., Magdy Abd El Razek M., Mandisarisa J., Mangalam S., Marcenes W., Meaney P.A., Margolis D.J., Silberberg D.H., Martin G.R., Martinez-Raga J., Marzan M.B., Mason-Jones A.J., McMahon B.J., Mehndiratta M.M., Woldeyohannes S.M., Tedla B.A., Zeleke B.M., Memiah P., Memish Z.A., Mendoza W., Meretoja T.J., Lallukka T., Mhimbira F.A., Micha R., Mozaff D., Shi P., Singh G.M., Miller T.R., Mohammad K.A., Mohammadi A., Mohan V., Mola G.L.D., Monasta L., Montico M., Ronfani L., Morawska L., Werdecker A., Mueller U.O., Westerman R., Musa K.I., Paternina Caicedo A.J., Seedat S., Nagel G., Rothenbacher D., Naidoo K.S., Sartorius B., Naldi L., Remuzzi G., Nangia V., Nash D., Nejjari C., Neupane S., Newton C.R., Ngalesoni F.N., Ngirabega J.D., Nguyen Q.L., Nkamedjie Pete P.M., Nomura M., Nyakarahuka L., Ogbo F.A., Ohkubo T., Olivares P.R., Olusanya B.O., Olusanya J.O., Opio J.N., Oren E., Ortiz A., Ota E., Ozdemir R., Mahesh P.A., Pandian J.D., Pant P.R., Papachristou C., Park E., Park J., Patten S.B., Tonelli M., Stokic Pejin L., Pereira D.M., Cortinovis M., Giussani G., Perico N., Pesudovs K., Pillay J.D., Plass D., Platts-Mills J.A., Polinder S., Pope C.A., Qorbani M., Rafay A., Rana S.M., Rahman M., Rahman S.U., Rai R.K., Rajsic S., Raju M., Rakovac I., Ranabhat C.L., Rangaswamy T., Ribeiro A.L., Ricci S., Roca A., Rojas-Rueda D., Roy N.K., Ruhago G.M., Sunguya B.F., Saha S., Sahathevan R., Saleh M.M., Sanabria J.R., Sanchez-Nino M.D., Sanchez-Riera L., Sarmiento-Suarez R., Sawhney M., Schaub M.P., Schneider I.J.C., Silva D.A.S., Schutte A.E., Shaddick G., Shaheen A., Shahraz S., Shaikh M.A., Sharma R., Shetty B.P., Shin M., Shiri R., Sigfusdottir I.D., Silveira D.G.A., Silverberg J.I., Yano Y., Singh O.P., Singh P.K., Singh V., Soneji S., Soreide K., Soriano J.B., Sposato L.A., Sreeramareddy C.T., Stathopoulou V., Stein M.B., Stranges S., Stroumpoulis K., Swaminathan S., Sykes B.L., Tabares-Seisdedos R., Tabb K.M., Takala J.S., Talongwa R.T., Taye B., Ten Have M., Tuzcu E.M., Thomson A.J., Thurston G.D., Topor-Madry R., Topouzis F., Towbin J.A., Traebert J., Truelsen T., Trujillo U., Uchendu U.S., Ukwaja K.N., Uthman O.A., Van Dingenen R., van Donkelaar A., Vasankari T., Vasconcelos A.M.N., Venketasubramanian N., Vidavalur R., Violante F.S., Vlassov V.V., Wallin M.T., Weichenthal S., White R.A., Williams H.C., Wong J.Q., Woolf A.D., Xavier D., Xu G., Yakob B., Yan L.L., Yip P., Yonemoto N., Yonga G., Younis M.Z., Zaidi Z., Zaki M.E., Zannad F., Zavala D.E., Zeeb H., Zonies D., Zuhlke L.J., Brown A., Brown J., Singh A., Thrift A.G., Wang L., Wang H., Naghavi M., Allen C., Barber R.M., Carter A., Casey D.C., Charlson F.J., Chen A.Z., Coates M.M., Coggeshall M., Dandona L., Dicker D.J., Erskine H.E., Fitzmaurice C., Foreman K., Forouzanfar M.H., Fraser M.S., Fullman N., Goldberg E.M., Graetz N., Haagsma J.A., Hay S.I., Huynh C., Johnson C.O., Kassebaum N.J., Kulikoff X.R., Kutz M., Kyu H.H., Larson H.J., Leung J., Lim S.S., Lind M., Lozano R., Marquez N., Mikesell J., Mokdad A.H., Mooney M.D., Nguyen G., Nsoesie E., Pigott D.M., Pinho C., Roth G.A., Sandar L., Silpakit N., Sligar A., Sorensen R.J.D., Stanaway J., Steiner C., Teeple S., Thomas B.A., Troeger C., VanderZanden A., Vollset S.E., Wanga V., Whiteford H.A., Wolock T., Zoeckler L., Achoki T., Afshin A., Alexander L.T., Anderson G.M., Bell B., Biryukov S., Blore J.D., Cercy K., Chew A., Cohen A.J., Daoud F., Dossou E., Estep K., Flaxman A., Friedman J., Frostad J., Godwin W.W., Hancock J., Kemmer L., Khalil I.A., Liu P.Y., Masiye F., Millear A., Mirarefin M., Misganaw A., Moradi-Lakeh M., Morgan K., Ng M., Pain A., Quame-Amaglo J., Rao P., Reitsma M.B., Shackelford K.A., Sur P., Wagner J.A., Vos T., Lopez A.D., Murray C.J.L., Ellenbogen R.G., Mock C.N., Quistberg D.A., Anderson B.O., Blosser C.D., Futran N.D., Heckbert S.R., Jensen P.N., Montine T.J., Tirschwell D.L., Watkins D.A., Bhutta Z.A., Nisar M.I., Akseer N., Alam N.K.M., Knibbs L.D., Lalloo R., Gouda H.N., McGrath J.J., Jeemon P., Dandona R., Kumar G.A., Gething P.W., Cooper C., Darby S.C., Deribew A., Ali R., Bennett D.A., Jha V., Rahimi K., Kinfu Y., Faghmous I.D.A., Langan S.M., McKee M., Murthy G.V.S., Pearce N., Roberts B., Campos-Nonato I.R., Campuzano J.C., Gomez-Dantes H., Heredia-Pi I.B., Mejia-Rodriguez F., Montanez Hernandez J.C., Montero P., Rios Blancas M.J., Servan-Mori E.E., Villalpando S., Duan L., Liu S., Ye P., Liang X., Yu S., Mensah G.A., Salomon J.A., Thorne-Lyman A.L., Ajala O.N., Barnighausen T., Ding E.L., Farvid M.S., Wagner G.R., James P., Osman M., Shrime M.G., Fitchett J.R.A., Knudsen A.K., Ellingsen C.L., Krog N.H., Savic M., Hailu A.D., Norheim O.F., Abate K.H., Gebrehiwot T.T., Gebremedhin A.T., Abbafati C., Abbas K.M., Abd-Allah F., Abera S.F., Alasfoor D., Melaku Y.A., Tesfay F.H., Abyu G.Y., Aregay A.F., Betsu B.D., Gebru A.A., Hailu G.B., Yalew A.Z., Yebyo H.G., Abreu D.M.X., Franca E.B., Abu-Raddad L.J., Adelekan A.L., Akinyemi R.O., Ojelabi F.A., Ademi Z., Furst T., Azzopardi P., Cowie B.C., Gibney K.B., MacLachlan J.H., Meretoja A., Alam K., Colquhoun S.M., Patton G.C., Weintraub R.G., Szoeke C.E.I., Vijayakumar L., Bohensky M.A., Taylor H.R., Wijeratne T., Adou A.K., Adsuar J.C., Afanvi K.A., Agardh E.E., Rehm J., Badawi A., Lindsay M.P., Popova S., Agarwal A., Agrawal A., Hotez P.J., Ahmad Kiadaliri A., Norrving B., Akanda A.S., Akinyemiju T.F., Schwebel D.C., Singh J.A., Al Lami F.H., Alabed S., Al-Aly Z., Driscoll T.R., Leigh J., Kemp A.H., Aldhahri S.F., Altirkawi K.A., Terkawi A.S., Aldridge R.W., Banerjee A., Tillmann T., Alegretti M.A., Aleman A.V., Cavalleri F., Colistro V., Alemu Z.A., Alkerwi A., Alla F., Allebeck P., Carrero J.J., Fereshtehnejad S., Weiderpass E., Havmoeller R., Al-Raddadi R., Alsharif U., Alvarez Martin E., Alvis-Guzman N., Amare A.T., Ciobanu L.G., Tessema G.A., Amegah A.K., Kudom A.A., Ameh E.A., Amini H., Karema C.K., Ammar W., Harb H.L., Amrock S.M., Andersen H.H., Antonio C.A.T., Faraon E.J.A., Arnlov J., Larsson A., Arsic Arsenijevic V.S., Barac A., Artaman A., Asayesh H., Asghar R.J., Atique S., Avokpaho E.F.G.A., Gankpe F.G., Awasthi A., Bacha U., Bahit M.C., Balakrishnan K., Barker-Collo S.L., Mohammed S., Barregard L., Petzold M., Barrero L.H., Basu A., Basu S., Bayou Y.T., Bazargan-Hejazi S., Beardsley J., Bedi N., Beghi E., Deribe K., Belay H.A., Giref A.Z., Haile D., Jibat T., Manamo W.A.A., Tefera W.M., Yirsaw B.D., Sheth K.N., Bell M.L., Biroscak B.J., Bello A.K., Santos I.S., Bensenor I.M., Lotufo P.A., Berhane A., Wolfe C.D.A., Bernabe E., Beyene A.S., Gishu M.D., Bhala N., Bhalla A., Biadgilign S., Bikbov B., Bin Abdulhak A.A., Bjertness E., Htet A.S., Bose D., Bourne R.R.A., Brainin M., Brayne C.E.G., Brazinova A., Majdan M., Shen J., Breitborde N.J.K., Brenner H., Schottker B., Brewer J.D., Brugha T.S., Buckle G.C., Gosselin R.A., Butt Z.A., Calabria B., Lal A., Lucas R.M., Degenhardt L., Resnikoff S., Carapetis J.R., Cardenas R., Carpenter D.O., Castaneda-Orjuela C.A., Castillo Rivas J., Catala-Lopez F., Cerda J., Chen W., Chiang P.P., Chibalabala M., Chibueze C.E., Mori R., Chimed-Ochir O., Jiang Y., Takahashi K., Chisumpa V.H., Mapoma C.C., Choi J.J., Chowdhury R., Christensen H., Christopher D.J., Cirillo M., Colomar M., Cooper L.T., Crump J.A., Poulton R.G., Damsere-Derry J., Danawi H., Refaat A.H., Dargan P.I., das Neves J., Massano J., Pedro J.M., Davey G., Davis A.C., Greaves F., Newton J.N., Davitoiu D.V., de Castro E.F., de Jager P., De D., Dellavalle R.P., Dharmaratne S.D., Dhillon P.K., Ganguly P., Lal D.K., Zodpey S., Diaz-Torne C., dos Santos K.P.B., Dubey M., Rahman M.H.U., Duncan B.B., Kieling C., Schmidt M.I., Elyazar I., Endries A.Y., Ermakov S.P., Eshrati B., Esteghamati A., Hafezi-Nejad N., Fahimi S., Malekzadeh R., Roshandel G., Sepanlou S.G., Farzadfar F., Kasaeian A., Parsaeian M., Heydarpour P., Rahimi-Movaghar V., Sheikhbahaei S., Yaseri M., Farid T.A., Khan A.R., Farinha C.S.E.S., Faro A., Feigin V.L., Te Ao B.J., Fernandes J.G., Fernandes J.C., Fischer F., Foigt N., Shiue I., Fowkes F.G.R., Franklin R.C., Piel F.B., Majeed A., Gall S.L., Gambashidze K., Gamkrelidze A., Kereselidze M., Shakh-Nazarova M., Iyer V.J., Gebre T., Geleijnse J.M., Gessner B.D., Ghoshal A.G., Gillum R.F., Mehari A., Gilmour S., Inoue M., Kawakami N., Shibuya K., Giroud M., Glaser E., Halasa Y.A., Shepard D.S., Undurraga E.A., Gona P., Goodridge A., Gopalani S.V., Gotay C.C., Kissoon N., Kopec J.A., Murthy S., Pourmalek F., Goto A., Gugnani H.C., Gupta R., Gupta V., Gutierrez R.A., Hamadeh R.R., Hamidi S., Handal A.J., Hankey G.J., Norman P.E., Hao Y., Harikrishnan S., Haro J.M., Hilderink H.B., Hoek H.W., Tura A.K., Hogg R.S., Horino M., Horita N., Hosgood H.D., Hoy D.G., Hsairi M., Htike M.M.T., Hu G., Huang C., Huang H., Huiart L., Husseini A., Huybrechts I., Huynh G., Iburg K.M., Innos K., Jacobs T.A., Jacobsen K.H., Jahanmehr N., Katibeh M., Rajavi Z., Jakovljevic M.B., Javanbakht M., Jayaraman S.P., Jayatilleke A.U., Prabhakaran D., Jiang G., Jimenez-Corona A., Jonas J.B., Joshi T.K., Kabir Z., Kamal R., Kesavachandran C.N., She J., Shen Z., Zhang H., Kan H., Kant S., Karch A., Karimkhani C., Karletsos D., Karthikeyan G., Naik N., Paul V.K., Roy A., Sagar R., Satpathy M., Tandon N., Kaul A., Kayibanda J.F., Keiyoro P.N., Lyons R.A., Parry C.D., Kengne A.P., Matzopoulos R., Wiysonge C.S., Stein D.J., Mayosi B.M., Keren A., Khader Y.S., Khan E.A., Khang Y.H., Won S., Khera S., Tavakkoli M., Khoja T.A.M., Kim D., Kim Y.J., Kissela B.M., Kokubo Y., Kolte D., McGarvey S.T., Kosen S., Koul P.A., Koyanagi A., Kuate Defo B., Kucuk Bicer B., Kuipers E.J., Kulkarni V.S., Kwan G.F., Rao S.R., Lam H., Lam J.O., Nachega J.B., Tran B.X., Lansingh V.C., Laryea D.O., Latif A.A., Lawrynowicz A.E.B., Levi M., Li Y., Alhabib S., Lipshultz S.E., Wilkinson J.D., Simard E.P., Liu Y., Phillips M.R., Xiao Q., Lo L., Logroscino G., Lunevicius R., Ma S., Machado V.M., Mackay M.T., Magdy Abd El Razek H., Magdy Abd El Razek M., Mandisarisa J., Mangalam S., Marcenes W., Meaney P.A., Margolis D.J., Silberberg D.H., Martin G.R., Martinez-Raga J., Marzan M.B., Mason-Jones A.J., McMahon B.J., Mehndiratta M.M., Woldeyohannes S.M., Tedla B.A., Zeleke B.M., Memiah P., Memish Z.A., Mendoza W., Meretoja T.J., Lallukka T., Mhimbira F.A., Micha R., Mozaff D., Shi P., Singh G.M., Miller T.R., Mohammad K.A., Mohammadi A., Mohan V., Mola G.L.D., Monasta L., Montico M., Ronfani L., Morawska L., Werdecker A., Mueller U.O., Westerman R., Musa K.I., Paternina Caicedo A.J., Seedat S., Nagel G., Rothenbacher D., Naidoo K.S., Sartorius B., Naldi L., Remuzzi G., Nangia V., Nash D., Nejjari C., Neupane S., Newton C.R., Ngalesoni F.N., Ngirabega J.D., Nguyen Q.L., Nkamedjie Pete P.M., Nomura M., Nyakarahuka L., Ogbo F.A., Ohkubo T., Olivares P.R., Olusanya B.O., Olusanya J.O., Opio J.N., Oren E., Ortiz A., Ota E., Ozdemir R., Mahesh P.A., Pandian J.D., Pant P.R., Papachristou C., Park E., Park J., Patten S.B., Tonelli M., Stokic Pejin L., Pereira D.M., Cortinovis M., Giussani G., Perico N., Pesudovs K., Pillay J.D., Plass D., Platts-Mills J.A., Polinder S., Pope C.A., Qorbani M., Rafay A., Rana S.M., Rahman M., Rahman S.U., Rai R.K., Rajsic S., Raju M., Rakovac I., Ranabhat C.L., Rangaswamy T., Ribeiro A.L., Ricci S., Roca A., Rojas-Rueda D., Roy N.K., Ruhago G.M., Sunguya B.F., Saha S., Sahathevan R., Saleh M.M., Sanabria J.R., Sanchez-Nino M.D., Sanchez-Riera L., Sarmiento-Suarez R., Sawhney M., Schaub M.P., Schneider I.J.C., Silva D.A.S., Schutte A.E., Shaddick G., Shaheen A., Shahraz S., Shaikh M.A., Sharma R., Shetty B.P., Shin M., Shiri R., Sigfusdottir I.D., Silveira D.G.A., Silverberg J.I., Yano Y., Singh O.P., Singh P.K., Singh V., Soneji S., Soreide K., Soriano J.B., Sposato L.A., Sreeramareddy C.T., Stathopoulou V., Stein M.B., Stranges S., Stroumpoulis K., Swaminathan S., Sykes B.L., Tabares-Seisdedos R., Tabb K.M., Takala J.S., Talongwa R.T., Taye B., Ten Have M., Tuzcu E.M., Thomson A.J., Thurston G.D., Topor-Madry R., Topouzis F., Towbin J.A., Traebert J., Truelsen T., Trujillo U., Uchendu U.S., Ukwaja K.N., Uthman O.A., Van Dingenen R., van Donkelaar A., Vasankari T., Vasconcelos A.M.N., Venketasubramanian N., Vidavalur R., Violante F.S., Vlassov V.V., Wallin M.T., Weichenthal S., White R.A., Williams H.C., Wong J.Q., Woolf A.D., Xavier D., Xu G., Yakob B., Yan L.L., Yip P., Yonemoto N., Yonga G., Younis M.Z., Zaidi Z., Zaki M.E., Zannad F., Zavala D.E., Zeeb H., Zonies D., Zuhlke L.J., Brown A., Brown J., Singh A., Thrift A.G., Wang L., Wang H., Naghavi M., Allen C., Barber R.M., Carter A., Casey D.C., Charlson F.J., Chen A.Z., Coates M.M., Coggeshall M., Dandona L., Dicker D.J., Erskine H.E., Fitzmaurice C., Foreman K., Forouzanfar M.H., Fraser M.S., Fullman N., Goldberg E.M., Graetz N., Haagsma J.A., Hay S.I., Huynh C., Johnson C.O., Kassebaum N.J., Kulikoff X.R., Kutz M., Kyu H.H., Larson H.J., Leung J., Lim S.S., Lind M., Lozano R., Marquez N., Mikesell J., Mokdad A.H., Mooney M.D., Nguyen G., Nsoesie E., Pigott D.M., Pinho C., Roth G.A., Sandar L., Silpakit N., Sligar A., Sorensen R.J.D., Stanaway J., Steiner C., Teeple S., Thomas B.A., Troeger C., VanderZanden A., Vollset S.E., Wanga V., Whiteford H.A., Wolock T., Zoeckler L., Achoki T., Afshin A., Alexander L.T., Anderson G.M., Bell B., Biryukov S., Blore J.D., Cercy K., Chew A., Cohen A.J., Daoud F., Dossou E., Estep K., Flaxman A., Friedman J., Frostad J., Godwin W.W., Hancock J., Kemmer L., Khalil I.A., Liu P.Y., Masiye F., Millear A., Mirarefin M., Misganaw A., Moradi-Lakeh M., Morgan K., Ng M., Pain A., Quame-Amaglo J., Rao P., Reitsma M.B., Shackelford K.A., Sur P., Wagner J.A., Vos T., Lopez A.D., Murray C.J.L., Ellenbogen R.G., Mock C.N., Quistberg D.A., Anderson B.O., Blosser C.D., Futran N.D., Heckbert S.R., Jensen P.N., Montine T.J., Tirschwell D.L., Watkins D.A., Bhutta Z.A., Nisar M.I., Akseer N., Alam N.K.M., Knibbs L.D., Lalloo R., Gouda H.N., McGrath J.J., Jeemon P., Dandona R., Kumar G.A., Gething P.W., Cooper C., Darby S.C., Deribew A., Ali R., Bennett D.A., Jha V., Rahimi K., Kinfu Y., Faghmous I.D.A., Langan S.M., McKee M., Murthy G.V.S., Pearce N., Roberts B., Campos-Nonato I.R., Campuzano J.C., Gomez-Dantes H., Heredia-Pi I.B., Mejia-Rodriguez F., Montanez Hernandez J.C., Montero P., Rios Blancas M.J., Servan-Mori E.E., Villalpando S., Duan L., Liu S., Ye P., Liang X., Yu S., Mensah G.A., Salomon J.A., Thorne-Lyman A.L., Ajala O.N., Barnighausen T., Ding E.L., Farvid M.S., Wagner G.R., James P., Osman M., Shrime M.G., Fitchett J.R.A., Knudsen A.K., Ellingsen C.L., Krog N.H., Savic M., Hailu A.D., Norheim O.F., Abate K.H., Gebrehiwot T.T., Gebremedhin A.T., Abbafati C., Abbas K.M., Abd-Allah F., Abera S.F., Alasfoor D., Melaku Y.A., Tesfay F.H., Abyu G.Y., Aregay A.F., Betsu B.D., Gebru A.A., Hailu G.B., Yalew A.Z., Yebyo H.G., Abreu D.M.X., Franca E.B., Abu-Raddad L.J., Adelekan A.L., Akinyemi R.O., Ojelabi F.A., Ademi Z., Furst T., Azzopardi P., Cowie B.C., Gibney K.B., MacLachlan J.H., Meretoja A., Alam K., Colquhoun S.M., Patton G.C., Weintraub R.G., Szoeke C.E.I., Vijayakumar L., Bohensky M.A., Taylor H.R., Wijeratne T., Adou A.K., Adsuar J.C., Afanvi K.A., Agardh E.E., Rehm J., Badawi A., Lindsay M.P., Popova S., Agarwal A., Agrawal A., Hotez P.J., Ahmad Kiadaliri A., Norrving B., Akanda A.S., Akinyemiju T.F., Schwebel D.C., Singh J.A., Al Lami F.H., Alabed S., Al-Aly Z., Driscoll T.R., Leigh J., Kemp A.H., Aldhahri S.F., Altirkawi K.A., Terkawi A.S., Aldridge R.W., Banerjee A., Tillmann T., Alegretti M.A., Aleman A.V., Cavalleri F., Colistro V., Alemu Z.A., Alkerwi A., Alla F., Allebeck P., Carrero J.J., Fereshtehnejad S., Weiderpass E., Havmoeller R., Al-Raddadi R., Alsharif U., Alvarez Martin E., Alvis-Guzman N., Amare A.T., Ciobanu L.G., Tessema G.A., Amegah A.K., Kudom A.A., Ameh E.A., Amini H., Karema C.K., Ammar W., Harb H.L., Amrock S.M., Andersen H.H., Antonio C.A.T., Faraon E.J.A., Arnlov J., Larsson A., Arsic Arsenijevic V.S., Barac A., Artaman A., Asayesh H., Asghar R.J., Atique S., Avokpaho E.F.G.A., Gankpe F.G., Awasthi A., Bacha U., Bahit M.C., Balakrishnan K., Barker-Collo S.L., Mohammed S., Barregard L., Petzold M., Barrero L.H., Basu A., Basu S., Bayou Y.T., Bazargan-Hejazi S., Beardsley J., Bedi N., Beghi E., Deribe K., Belay H.A., Giref A.Z., Haile D., Jibat T., Manamo W.A.A., Tefera W.M., Yirsaw B.D., Sheth K.N., Bell M.L., Biroscak B.J., Bello A.K., Santos I.S., Bensenor I.M., Lotufo P.A., Berhane A., Wolfe C.D.A., Bernabe E., Beyene A.S., Gishu M.D., Bhala N., Bhalla A., Biadgilign S., Bikbov B., Bin Abdulhak A.A., Bjertness E., Htet A.S., Bose D., Bourne R.R.A., Brainin M., Brayne C.E.G., Brazinova A., Majdan M., Shen J., Breitborde N.J.K., Brenner H., Schottker B., Brewer J.D., Brugha T.S., Buckle G.C., Gosselin R.A., Butt Z.A., Calabria B., Lal A., Lucas R.M., Degenhardt L., Resnikoff S., Carapetis J.R., Cardenas R., Carpenter D.O., Castaneda-Orjuela C.A., Castillo Rivas J., Catala-Lopez F., Cerda J., Chen W., Chiang P.P., Chibalabala M., Chibueze C.E., Mori R., Chimed-Ochir O., Jiang Y., Takahashi K., Chisumpa V.H., Mapoma C.C., Choi J.J., Chowdhury R., Christensen H., Christopher D.J., Cirillo M., Colomar M., Cooper L.T., Crump J.A., Poulton R.G., Damsere-Derry J., Danawi H., Refaat A.H., Dargan P.I., das Neves J., Massano J., Pedro J.M., Davey G., Davis A.C., Greaves F., Newton J.N., Davitoiu D.V., de Castro E.F., de Jager P., De D., Dellavalle R.P., Dharmaratne S.D., Dhillon P.K., Ganguly P., Lal D.K., Zodpey S., Diaz-Torne C., dos Santos K.P.B., Dubey M., Rahman M.H.U., Duncan B.B., Kieling C., Schmidt M.I., Elyazar I., Endries A.Y., Ermakov S.P., Eshrati B., Esteghamati A., Hafezi-Nejad N., Fahimi S., Malekzadeh R., Roshandel G., Sepanlou S.G., Farzadfar F., Kasaeian A., Parsaeian M., Heydarpour P., Rahimi-Movaghar V., Sheikhbahaei S., Yaseri M., Farid T.A., Khan A.R., Farinha C.S.E.S., Faro A., Feigin V.L., Te Ao B.J., Fernandes J.G., Fernandes J.C., Fischer F., Foigt N., Shiue I., Fowkes F.G.R., Franklin R.C., Piel F.B., Majeed A., Gall S.L., Gambashidze K., Gamkrelidze A., Kereselidze M., Shakh-Nazarova M., Iyer V.J., Gebre T., Geleijnse J.M., Gessner B.D., Ghoshal A.G., Gillum R.F., Mehari A., Gilmour S., Inoue M., Kawakami N., Shibuya K., Giroud M., Glaser E., Halasa Y.A., Shepard D.S., Undurraga E.A., Gona P., Goodridge A., Gopalani S.V., Gotay C.C., Kissoon N., Kopec J.A., Murthy S., Pourmalek F., Goto A., Gugnani H.C., Gupta R., Gupta V., Gutierrez R.A., Hamadeh R.R., Hamidi S., Handal A.J., Hankey G.J., Norman P.E., Hao Y., Harikrishnan S., Haro J.M., Hilderink H.B., Hoek H.W., Tura A.K., Hogg R.S., Horino M., Horita N., Hosgood H.D., Hoy D.G., Hsairi M., Htike M.M.T., Hu G., Huang C., Huang H., Huiart L., Husseini A., Huybrechts I., Huynh G., Iburg K.M., Innos K., Jacobs T.A., Jacobsen K.H., Jahanmehr N., Katibeh M., Rajavi Z., Jakovljevic M.B., Javanbakht M., Jayaraman S.P., Jayatilleke A.U., Prabhakaran D., Jiang G., Jimenez-Corona A., Jonas J.B., Joshi T.K., Kabir Z., Kamal R., Kesavachandran C.N., She J., Shen Z., Zhang H., Kan H., Kant S., Karch A., Karimkhani C., Karletsos D., Karthikeyan G., Naik N., Paul V.K., Roy A., Sagar R., Satpathy M., Tandon N., Kaul A., Kayibanda J.F., Keiyoro P.N., Lyons R.A., Parry C.D., Kengne A.P., Matzopoulos R., Wiysonge C.S., Stein D.J., Mayosi B.M., Keren A., Khader Y.S., Khan E.A., Khang Y.H., Won S., Khera S., Tavakkoli M., Khoja T.A.M., Kim D., Kim Y.J., Kissela B.M., Kokubo Y., Kolte D., McGarvey S.T., Kosen S., Koul P.A., Koyanagi A., Kuate Defo B., Kucuk Bicer B., Kuipers E.J., Kulkarni V.S., Kwan G.F., Rao S.R., Lam H., Lam J.O., Nachega J.B., Tran B.X., Lansingh V.C., Laryea D.O., Latif A.A., Lawrynowicz A.E.B., Levi M., and Li Y.

Abstract

Background Improving survival and extending the longevity of life for all populations requires timely, robust evidence on local mortality levels and trends. The Global Burden of Disease 2015 Study (GBD 2015) provides a comprehensive assessment of all-cause and cause-specific mortality for 249 causes in 195 countries and territories from 1980 to 2015. These results informed an in-depth investigation of observed and expected mortality patterns based on sociodemographic measures. Methods We estimated all-cause mortality by age, sex, geography, and year using an improved analytical approach originally developed for GBD 2013 and GBD 2010. Improvements included refinements to the estimation of child and adult mortality and corresponding uncertainty, parameter selection for under-5 mortality synthesis by spatiotemporal Gaussian process regression, and sibling history data processing. We also expanded the database of vital registration, survey, and census data to 14 294 geography-year datapoints. For GBD 2015, eight causes, including Ebola virus disease, were added to the previous GBD cause list for mortality. We used six modelling approaches to assess cause-specific mortality, with the Cause of Death Ensemble Model (CODEm) generating estimates for most causes. We used a series of novel analyses to systematically quantify the drivers of trends in mortality across geographies. First, we assessed observed and expected levels and trends of cause-specific mortality as they relate to the Socio-demographic Index (SDI), a summary indicator derived from measures of income per capita, educational attainment, and fertility. Second, we examined factors affecting total mortality patterns through a series of counterfactual scenarios, testing the magnitude by which population growth, population age structures, and epidemiological changes contributed to shifts in mortality. Finally, we attributed changes in life expectancy to changes in cause of death. We documented each step of the GBD 2

Published
2016

23. Measuring the health-related Sustainable Development Goals in 188 countries: a baseline analysis from the Global Burden of Disease Study 2015.

Author

Nguhiu P., Shigematsu M., Shin M., Yoon S., Shiri R., Shishani K., Sigfusdottir I.D., Silverberg J.I., Yano Y., Singh O.P., Singh P.K., Soreide K., Soriano J.B., Sposato L.A., Sreeramareddy C.T., Stahl H., Stathopoulou V., Steckling N., Stranges S., Strong M., Sunguya B.F., Swaminathan S., Sykes B.L., Tabares-Seisdedos R., Tabb K.M., Talongwa R.T., Tarawneh M.R., Tavakkoli M., Taye B., Tuzcu E.M., Thakur J., Thomson A.J., Thurston G.D., Tobe-Gai R., Topor-Madry R., Topouzis F., Tsala Dimbuene Z., Tyrovolas S., Ukwaja K.N., Uneke C.J., Uthman O.A., Vasankari T., Vasconcelos A.M.N., Venketasubramanian N., Violante F.S., Vlassov V.V., Volkow P., Wallin M.T., Weichenthal S., Woolf A.D., Wubshet M., Xu G., Yakob B., Yan L.L., Yip P., Yonemoto N., Younis M.Z., Yu C., Zaidi Z., Zaki M.E., Zambrana-Torrelio C., Zapata T., Zonies D., Singh A., Thrift A.G., Wang L., Lim S.S., Allen K., Dandona L., Forouzanfar M.H., Fullman N., Goldberg E.M., Hay S.I., Holmberg M., Kutz M.J., Larson H.J., Lopez A.D., McNellan C.R., Mokdad A.H., Mooney M.D., Naghavi M., Olsen H.E., Pigott D.M., Vos T., Wang H., Achoki T., Afshin A., Allen C., Anderson G.M., Barber R., Bienhoff K.A., Blore J., Brauer M., Carter A., Casey D., Charlson F.J., Chen A.Z., Coates M.M., Coggeshall M., Cohen A.J., Deshpande A., Erskine H.E., Ferrari A.J., Fitzmaurice C., Foreman K., Fraser M., Friedman J., Frostad J., Godwin W., Graetz N., Griswold M., Haagsma J.A., Haakenstad A., Kassebaum N.J., Kemmer L., Kulikoff X.R., Kyu H.H., Leung J., Lind M., Liu P.Y., Masiye F., Mirarefin M., Misganaw A., Moradi-Lakeh M., Nguyen G., Pinho C., Rao P.C., Reitsma M.B., Roth G.A., Santomauro D.F., Shackelford K., Silpakit N., Sligar A., Sorensen R.J.D., Stanaway J.D., Steiner C., Sur P., Vollset S.E., Wanga V., Whiteford H.A., Zhao Y., Zhou M., Murray C.J.L., Kotsakis G.A., Mock C.N., Anderson B.O., Watkins D.A., Bhutta Z.A., Nisar M.I., Akseer N., deVeber G.A., Jeemon P., Dandona R., Kumar G.A., Gething P.W., Bisanzio D., Cooper C., Ali R., Bennett D.A., Jha V., Weiss D.J., Kinfu Y., Patel V., Langan S.M., McKee M., Murthy G.V.S., Roberts B., Stockl H., Duan L., Jin Y., Li Y., Liu S., Ye P., Liang X., Azzopardi P., Cowie B.C., Meretoja A., Patton G.C., Alam K., Weintraub R.G., Sawyer S.M., Szoeke C.E.I., Taylor H.R., Lozano R., Barrientos-Gutierrez T., Campos-Nonato I.R., Campuzano J.C., Heredia-Pi I.B., Montanez Hernandez J.C., Rios Blancas M.J., Servan-Mori E.E., Shamah Levy T., Salomon J.A., Binagwaho A., Barnighausen T., Cahill L.E., Ding E.L., Farvid M.S., Wagner G.R., Thorne-Lyman A.L., James P., Fitchett J.R.A., Abajobir A.A., Knibbs L.D., Veerman J.L., Lalloo R., Gouda H.N., Guo Y., McGrath J.J., Abate K.H., Gebrehiwot T.T., Gebremedhin A.T., Abbafati C., Abbas K.M., Abd-Allah F., Abdulle A.M., Abraham B., Abubakar I., Aldridge R.W., Banerjee A., Benzian H., Tillmann T., Abu-Raddad L.J., Abu-Rmeileh N.M., Melaku Y.A., Abyu G.Y., Bayou T.A., Betsu B.D., Gebru A.A., Hailu G.B., Tekle D.Y., Yalew A.Z., Adebiyi A.O., Owolabi M.O., Akinyemi R.O., Adedeji I.A., Afanvi K.A., Micha R., Shi P., Singh G.M., Badawi A., Agarwal A., Agrawal A., Ahmad Kiadaliri A., Norrving B., Ahmadieh H., Yaseri M., Jahanmehr N., Ahmed K.Y., Alemu Z.A., Tegegne T.K., Akanda A.S., Akinyemiju T.F., Schwebel D.C., Singh J.A., Al-Aly Z., Driscoll T.R., Leigh J., Mekonnen A.B., Neal B., Alam U., Alasfoor D., AlBuhairan F.S., Alkhateeb M.A., Aldhahri S.F., Altirkawi K.A., Terkawi A.S., Alkerwi A., Alla F., Allebeck P., Rabiee R.H.S., Roy N., Kivipelto M., Carrero J.J., Fereshtehnejad S.M., Weiderpass E., Havmoeller R., Sindi S., Al-Raddadi R., Alvarez E., Alvis-Guzman N., Paternina Caicedo A.J., Amare A.T., Ciobanu L.G., Tessema G.A., Amberbir A., Amegah A.K., Amini H., Furst T., Karema C.K., Ammar W., Harb H.L., Amrock S.M., Andersen H.H., Antonio C.A.T., Anwari P., Arnlov J., Larsson A., Artaman A., Asayesh H., Asghar R.J., Atique S., Avokpaho E.F.G.A., Awasthi A., Ayala Quintanilla B.P., Bacha U., Balakrishnan K., Barac A., Barker-Collo S.L., Mohammed S., Barrero L.H., Basu S., Del L.C., Bazargan-Hejazi S., Beardsley J., Bedi N., Beghi E., Bejot Y., Sheth K.N., Bell M.L., Bello A.K., Santos I.S., Bensenor I.M., Lotufo P.A., Berhane A., Wolfe C.D., Bernabe E., Wolfe I., Bernal O.A., Roba H.S., Beyene A.S., Mesfin Y.M., Bhala N., Bhatt S., Biadgilign S., Bikbov B., Soneji S., Bjertness E., Htet A.S., Bourne R.R.A., Brainin M., Krueger H., Gotay C.C., Kissoon N., Murthy S., Pourmalek F., Brazinova A., Majdan M., Shen J., Breitborde N.J.K., Broday D.M., Brugha T.S., Buchbinder R., Gabbe B., Butt Z.A., van Donkelaar A., Martin R.V., Carabin H., Cardenas R., Caso V., Castaneda-Orjuela C.A., Castillo Rivas J., Catala-Lopez F., Cavalleri F., Cecilio P., das Neves J., Massano J., Pedro J.M., Chang H., Chang J., Che X., Chiang P.P., Chibalabala M., Chisumpa V.H., Mapoma C.C., Choi J.J., Chowdhury R., Christensen H., Cirillo M., Piel F.B., Rodriguez A., Cooke G.S., Majeed A., Cooper L.T., Crump J.A., Derrett S., Poulton R.G., Damtew S.A., Workie S.B., Deribe K., Tefera W., Giref A.Z., Haile D., Temam Shifa G., Dargan P.I., Davis A.C., Newton J.N., Steel N., Davletov K., de Castro E.F., De Leo D., Degenhardt L., Resnikoff S., Mitchell P.B., Des Jarlais D.C., Dey S., Dhillon P.K., Lal D.K., Zodpey S., Dharmaratne S.D., Dorsey E.R., Doyle K.E., Kemp A.H., Dubey M., Rahman M.H.U., Ram U., Verma R.K., Yadav A.K., Duncan B.B., Kieling C., Schmidt M.I., Ebrahimi H., Esteghamati A., Farzadfar F., Hafezi-Nejad N., Kasaeian A., Parsaeian M., Pishgar F., Sheikhbahaei S., Fahimi S., Malekzadeh R., Roshandel G., Sepanlou S.G., Hassanvand M.S., Khosravi A., Rahimi-Movaghar V., Endries A.Y., Ermakov S.P., Soshnikov S., Eshrati B., Farid T.A., Khan A.R., Farinha C.S.E.S., Faro A., Feigin V.L., Felicio M.M., Fernandes J.C., Fischer F., Foigt N., Shiue I., Fowkes F.G.R., Franca E.B., Franklin R.C., Garcia-Basteiro A.L., Gebre T., Gessner B.D., Gillum R.F., Mehari A., Ginawi I.A., Giroud M., Gishu M.D., Tura A.K., Gona P., Goodridge A., Gopalani S.V., Goto A., Inoue M., Greenwell K.F., Gupta R., Gupta V., Gutierrez R.A., Gyawali B., Iburg K.M., Halasa Y.A., Undurraga E.A., Hamadeh R.R., Hamidi S., Hammami M., Hankey G.J., Haro J.M., Hoek H.W., Skirbekk V., Horino M., Horita N., Hosgood H.D., Hoy D.G., Hu G., Huang H., Idrisov B.T., Kwan G.F., Kawakami N., Shibuya K., Islami F., Jacobs T.A., Jacobsen K.H., Jakovljevic M.B., Jansen H.A.F., Javanbakht M., Jayatilleke A.U., Jee S.H., Jiang Y., Jibat T., Jonas J.B., Kabir Z., Kalkonde Y., Kamal R., Kesavachandran C.N., She J., Kan H., Kandel A., Karch A., Karimkhani C., Karunapema P., Kaul A., Kayibanda J.F., Keiyoro P.N., Matzopoulos R., Parry C.D., Kengne A.P., Wiysonge C.S., Stein D.J., Mayosi B.M., Shey M., Keren A., Khader Y.S., Khan E.A., Khan G., Khang Y.H., Won S., Khoja T.A.M., Khubchandani J., Kim C., Kim D., Kim S., Kim Y.J., Kimokoti R.W., Kokubo Y., Kolte D., Kosen S., Koul P.A., Koyanagi A., Kravchenko M., Varakin Y.Y., Kuate Defo B., Kuchenbecker R.S., Kuipers E.J., Kulkarni V.S., Lal A., Lucas R.M., Lam H., Lan Q., Laryea D.O., Latif A.A., Leasher J.L., Leinsalu M., Leung R., Levi M., Linn S., Lipshultz S.E., Wilkinson J.D., Simard E.P., Liu Y., Phillips M.R., Lloyd B.K., Lo L., Logroscino G., Lunevicius R., Magdy M., Magis-Rodriguez C., Mahdavi M., Malta D.C., Meaney P.A., Margolis D.J., Martinez-Raga J., Mason-Jones A.J., Tedla B.A., Memiah P., Memish Z.A., Mendoza W., Mensink G.B.M., Meretoja T.J., Mhimbira F.A., Miller T.R., Mills E.J., Mohammadi A., Monasta L., Montico M., Ronfani L., Monis J.D., Morawska L., Sun J., Mori R., Werdecker A., Mueller U.O., Westerman R., Murdoch M.E., Murimira B., Murray J., Musa K.I., Nachega J.B., Seedat S., Tran B.X., Nagel G., Rothenbacher D., Naidoo K.S., Oladimeji O., Sartorius B., Zegeye E.A., Naldi L., Remuzzi G., Nangia V., Nejjari C., Newton C.R., Ngalesoni F.N., Nguyen Q.L., Nkamedjie P.M., Nolte S., Osborne R.H., Nomura M., Norheim O.F., Obermeyer C.M., Ogbo F.A., Oh I., Olivares P.R., Olusanya B.O., Olusanya J.O., Opio J.N., Oren E., Ortiz A., Ota E., Mahesh P.A., Park E., Park H., Patel T., Patil S.T., Patten S.B., Tonelli M., Paudel D., Pereira D.M., Perico N., Pesudovs K., Petzold M., Pillay J.D., Polinder S., Qorbani M., Radfar A., Rahman M., Rahman S.U., Rai R.K., Rajsic S., Raju M., Rana S.M., Ranabhat C.L., Ranganathan K., Refaat A.H., Ribeiro A.L., Rojas-Rueda D., Roy A., Sagar R., Satpathy M., Sackey B.B., Saleh M.M., Sanabria J.R., Sarmiento-Suarez R., Savic M., Sawhney M., Schmidhuber J., Schneider I.J.C., Silva D.A.S., Schutte A.E., Shaheen A., Shaikh M.A., Sharma R., Nguhiu P., Shigematsu M., Shin M., Yoon S., Shiri R., Shishani K., Sigfusdottir I.D., Silverberg J.I., Yano Y., Singh O.P., Singh P.K., Soreide K., Soriano J.B., Sposato L.A., Sreeramareddy C.T., Stahl H., Stathopoulou V., Steckling N., Stranges S., Strong M., Sunguya B.F., Swaminathan S., Sykes B.L., Tabares-Seisdedos R., Tabb K.M., Talongwa R.T., Tarawneh M.R., Tavakkoli M., Taye B., Tuzcu E.M., Thakur J., Thomson A.J., Thurston G.D., Tobe-Gai R., Topor-Madry R., Topouzis F., Tsala Dimbuene Z., Tyrovolas S., Ukwaja K.N., Uneke C.J., Uthman O.A., Vasankari T., Vasconcelos A.M.N., Venketasubramanian N., Violante F.S., Vlassov V.V., Volkow P., Wallin M.T., Weichenthal S., Woolf A.D., Wubshet M., Xu G., Yakob B., Yan L.L., Yip P., Yonemoto N., Younis M.Z., Yu C., Zaidi Z., Zaki M.E., Zambrana-Torrelio C., Zapata T., Zonies D., Singh A., Thrift A.G., Wang L., Lim S.S., Allen K., Dandona L., Forouzanfar M.H., Fullman N., Goldberg E.M., Hay S.I., Holmberg M., Kutz M.J., Larson H.J., Lopez A.D., McNellan C.R., Mokdad A.H., Mooney M.D., Naghavi M., Olsen H.E., Pigott D.M., Vos T., Wang H., Achoki T., Afshin A., Allen C., Anderson G.M., Barber R., Bienhoff K.A., Blore J., Brauer M., Carter A., Casey D., Charlson F.J., Chen A.Z., Coates M.M., Coggeshall M., Cohen A.J., Deshpande A., Erskine H.E., Ferrari A.J., Fitzmaurice C., Foreman K., Fraser M., Friedman J., Frostad J., Godwin W., Graetz N., Griswold M., Haagsma J.A., Haakenstad A., Kassebaum N.J., Kemmer L., Kulikoff X.R., Kyu H.H., Leung J., Lind M., Liu P.Y., Masiye F., Mirarefin M., Misganaw A., Moradi-Lakeh M., Nguyen G., Pinho C., Rao P.C., Reitsma M.B., Roth G.A., Santomauro D.F., Shackelford K., Silpakit N., Sligar A., Sorensen R.J.D., Stanaway J.D., Steiner C., Sur P., Vollset S.E., Wanga V., Whiteford H.A., Zhao Y., Zhou M., Murray C.J.L., Kotsakis G.A., Mock C.N., Anderson B.O., Watkins D.A., Bhutta Z.A., Nisar M.I., Akseer N., deVeber G.A., Jeemon P., Dandona R., Kumar G.A., Gething P.W., Bisanzio D., Cooper C., Ali R., Bennett D.A., Jha V., Weiss D.J., Kinfu Y., Patel V., Langan S.M., McKee M., Murthy G.V.S., Roberts B., Stockl H., Duan L., Jin Y., Li Y., Liu S., Ye P., Liang X., Azzopardi P., Cowie B.C., Meretoja A., Patton G.C., Alam K., Weintraub R.G., Sawyer S.M., Szoeke C.E.I., Taylor H.R., Lozano R., Barrientos-Gutierrez T., Campos-Nonato I.R., Campuzano J.C., Heredia-Pi I.B., Montanez Hernandez J.C., Rios Blancas M.J., Servan-Mori E.E., Shamah Levy T., Salomon J.A., Binagwaho A., Barnighausen T., Cahill L.E., Ding E.L., Farvid M.S., Wagner G.R., Thorne-Lyman A.L., James P., Fitchett J.R.A., Abajobir A.A., Knibbs L.D., Veerman J.L., Lalloo R., Gouda H.N., Guo Y., McGrath J.J., Abate K.H., Gebrehiwot T.T., Gebremedhin A.T., Abbafati C., Abbas K.M., Abd-Allah F., Abdulle A.M., Abraham B., Abubakar I., Aldridge R.W., Banerjee A., Benzian H., Tillmann T., Abu-Raddad L.J., Abu-Rmeileh N.M., Melaku Y.A., Abyu G.Y., Bayou T.A., Betsu B.D., Gebru A.A., Hailu G.B., Tekle D.Y., Yalew A.Z., Adebiyi A.O., Owolabi M.O., Akinyemi R.O., Adedeji I.A., Afanvi K.A., Micha R., Shi P., Singh G.M., Badawi A., Agarwal A., Agrawal A., Ahmad Kiadaliri A., Norrving B., Ahmadieh H., Yaseri M., Jahanmehr N., Ahmed K.Y., Alemu Z.A., Tegegne T.K., Akanda A.S., Akinyemiju T.F., Schwebel D.C., Singh J.A., Al-Aly Z., Driscoll T.R., Leigh J., Mekonnen A.B., Neal B., Alam U., Alasfoor D., AlBuhairan F.S., Alkhateeb M.A., Aldhahri S.F., Altirkawi K.A., Terkawi A.S., Alkerwi A., Alla F., Allebeck P., Rabiee R.H.S., Roy N., Kivipelto M., Carrero J.J., Fereshtehnejad S.M., Weiderpass E., Havmoeller R., Sindi S., Al-Raddadi R., Alvarez E., Alvis-Guzman N., Paternina Caicedo A.J., Amare A.T., Ciobanu L.G., Tessema G.A., Amberbir A., Amegah A.K., Amini H., Furst T., Karema C.K., Ammar W., Harb H.L., Amrock S.M., Andersen H.H., Antonio C.A.T., Anwari P., Arnlov J., Larsson A., Artaman A., Asayesh H., Asghar R.J., Atique S., Avokpaho E.F.G.A., Awasthi A., Ayala Quintanilla B.P., Bacha U., Balakrishnan K., Barac A., Barker-Collo S.L., Mohammed S., Barrero L.H., Basu S., Del L.C., Bazargan-Hejazi S., Beardsley J., Bedi N., Beghi E., Bejot Y., Sheth K.N., Bell M.L., Bello A.K., Santos I.S., Bensenor I.M., Lotufo P.A., Berhane A., Wolfe C.D., Bernabe E., Wolfe I., Bernal O.A., Roba H.S., Beyene A.S., Mesfin Y.M., Bhala N., Bhatt S., Biadgilign S., Bikbov B., Soneji S., Bjertness E., Htet A.S., Bourne R.R.A., Brainin M., Krueger H., Gotay C.C., Kissoon N., Murthy S., Pourmalek F., Brazinova A., Majdan M., Shen J., Breitborde N.J.K., Broday D.M., Brugha T.S., Buchbinder R., Gabbe B., Butt Z.A., van Donkelaar A., Martin R.V., Carabin H., Cardenas R., Caso V., Castaneda-Orjuela C.A., Castillo Rivas J., Catala-Lopez F., Cavalleri F., Cecilio P., das Neves J., Massano J., Pedro J.M., Chang H., Chang J., Che X., Chiang P.P., Chibalabala M., Chisumpa V.H., Mapoma C.C., Choi J.J., Chowdhury R., Christensen H., Cirillo M., Piel F.B., Rodriguez A., Cooke G.S., Majeed A., Cooper L.T., Crump J.A., Derrett S., Poulton R.G., Damtew S.A., Workie S.B., Deribe K., Tefera W., Giref A.Z., Haile D., Temam Shifa G., Dargan P.I., Davis A.C., Newton J.N., Steel N., Davletov K., de Castro E.F., De Leo D., Degenhardt L., Resnikoff S., Mitchell P.B., Des Jarlais D.C., Dey S., Dhillon P.K., Lal D.K., Zodpey S., Dharmaratne S.D., Dorsey E.R., Doyle K.E., Kemp A.H., Dubey M., Rahman M.H.U., Ram U., Verma R.K., Yadav A.K., Duncan B.B., Kieling C., Schmidt M.I., Ebrahimi H., Esteghamati A., Farzadfar F., Hafezi-Nejad N., Kasaeian A., Parsaeian M., Pishgar F., Sheikhbahaei S., Fahimi S., Malekzadeh R., Roshandel G., Sepanlou S.G., Hassanvand M.S., Khosravi A., Rahimi-Movaghar V., Endries A.Y., Ermakov S.P., Soshnikov S., Eshrati B., Farid T.A., Khan A.R., Farinha C.S.E.S., Faro A., Feigin V.L., Felicio M.M., Fernandes J.C., Fischer F., Foigt N., Shiue I., Fowkes F.G.R., Franca E.B., Franklin R.C., Garcia-Basteiro A.L., Gebre T., Gessner B.D., Gillum R.F., Mehari A., Ginawi I.A., Giroud M., Gishu M.D., Tura A.K., Gona P., Goodridge A., Gopalani S.V., Goto A., Inoue M., Greenwell K.F., Gupta R., Gupta V., Gutierrez R.A., Gyawali B., Iburg K.M., Halasa Y.A., Undurraga E.A., Hamadeh R.R., Hamidi S., Hammami M., Hankey G.J., Haro J.M., Hoek H.W., Skirbekk V., Horino M., Horita N., Hosgood H.D., Hoy D.G., Hu G., Huang H., Idrisov B.T., Kwan G.F., Kawakami N., Shibuya K., Islami F., Jacobs T.A., Jacobsen K.H., Jakovljevic M.B., Jansen H.A.F., Javanbakht M., Jayatilleke A.U., Jee S.H., Jiang Y., Jibat T., Jonas J.B., Kabir Z., Kalkonde Y., Kamal R., Kesavachandran C.N., She J., Kan H., Kandel A., Karch A., Karimkhani C., Karunapema P., Kaul A., Kayibanda J.F., Keiyoro P.N., Matzopoulos R., Parry C.D., Kengne A.P., Wiysonge C.S., Stein D.J., Mayosi B.M., Shey M., Keren A., Khader Y.S., Khan E.A., Khan G., Khang Y.H., Won S., Khoja T.A.M., Khubchandani J., Kim C., Kim D., Kim S., Kim Y.J., Kimokoti R.W., Kokubo Y., Kolte D., Kosen S., Koul P.A., Koyanagi A., Kravchenko M., Varakin Y.Y., Kuate Defo B., Kuchenbecker R.S., Kuipers E.J., Kulkarni V.S., Lal A., Lucas R.M., Lam H., Lan Q., Laryea D.O., Latif A.A., Leasher J.L., Leinsalu M., Leung R., Levi M., Linn S., Lipshultz S.E., Wilkinson J.D., Simard E.P., Liu Y., Phillips M.R., Lloyd B.K., Lo L., Logroscino G., Lunevicius R., Magdy M., Magis-Rodriguez C., Mahdavi M., Malta D.C., Meaney P.A., Margolis D.J., Martinez-Raga J., Mason-Jones A.J., Tedla B.A., Memiah P., Memish Z.A., Mendoza W., Mensink G.B.M., Meretoja T.J., Mhimbira F.A., Miller T.R., Mills E.J., Mohammadi A., Monasta L., Montico M., Ronfani L., Monis J.D., Morawska L., Sun J., Mori R., Werdecker A., Mueller U.O., Westerman R., Murdoch M.E., Murimira B., Murray J., Musa K.I., Nachega J.B., Seedat S., Tran B.X., Nagel G., Rothenbacher D., Naidoo K.S., Oladimeji O., Sartorius B., Zegeye E.A., Naldi L., Remuzzi G., Nangia V., Nejjari C., Newton C.R., Ngalesoni F.N., Nguyen Q.L., Nkamedjie P.M., Nolte S., Osborne R.H., Nomura M., Norheim O.F., Obermeyer C.M., Ogbo F.A., Oh I., Olivares P.R., Olusanya B.O., Olusanya J.O., Opio J.N., Oren E., Ortiz A., Ota E., Mahesh P.A., Park E., Park H., Patel T., Patil S.T., Patten S.B., Tonelli M., Paudel D., Pereira D.M., Perico N., Pesudovs K., Petzold M., Pillay J.D., Polinder S., Qorbani M., Radfar A., Rahman M., Rahman S.U., Rai R.K., Rajsic S., Raju M., Rana S.M., Ranabhat C.L., Ranganathan K., Refaat A.H., Ribeiro A.L., Rojas-Rueda D., Roy A., Sagar R., Satpathy M., Sackey B.B., Saleh M.M., Sanabria J.R., Sarmiento-Suarez R., Savic M., Sawhney M., Schmidhuber J., Schneider I.J.C., Silva D.A.S., Schutte A.E., Shaheen A., Shaikh M.A., and Sharma R.

Abstract

Background In September, 2015, the UN General Assembly established the Sustainable Development Goals (SDGs). The SDGs specify 17 universal goals, 169 targets, and 230 indicators leading up to 2030. We provide an analysis of 33 health-related SDG indicators based on the Global Burden of Diseases, Injuries, and Risk Factors Study 2015 (GBD 2015). Methods We applied statistical methods to systematically compiled data to estimate the performance of 33 health-related SDG indicators for 188 countries from 1990 to 2015. We rescaled each indicator on a scale from 0 (worst observed value between 1990 and 2015) to 100 (best observed). Indices representing all 33 health-related SDG indicators (health-related SDG index), health-related SDG indicators included in the Millennium Development Goals (MDG index), and health-related indicators not included in the MDGs (non-MDG index) were computed as the geometric mean of the rescaled indicators by SDG target. We used spline regressions to examine the relations between the Socio-demographic Index (SDI, a summary measure based on average income per person, educational attainment, and total fertility rate) and each of the health-related SDG indicators and indices. Findings In 2015, the median health-related SDG index was 59.3 (95% uncertainty interval 56.8-61.8) and varied widely by country, ranging from 85.5 (84.2-86.5) in Iceland to 20.4 (15.4-24.9) in Central African Republic. SDI was a good predictor of the health-related SDG index (r2=0.88) and the MDG index (r2=0.92), whereas the non-MDG index had a weaker relation with SDI (r2=0.79). Between 2000 and 2015, the health-related SDG index improved by a median of 7.9 (IQR 5.0-10.4), and gains on the MDG index (a median change of 10.0 [6.7-13.1]) exceeded that of the non-MDG index (a median change of 5.5 [2.1-8.9]). Since 2000, pronounced progress occurred for indicators such as met need with modern contraception, under-5 mortality, and neonatal mortality, as well as the indicator for

Published
2016

34. Synergistic inhibitor effect of cetylpyridinium chloride and other halides on the corrosion of mild steel in 0.5M H2SO4

Author

Khamis, A., Saleh, M.M., and Awad, M.I.

Subjects
*CETYLPYRIDINIUM chloride, *HALIDES, *MILD steel, *STEEL corrosion, *ELECTROCHEMICAL analysis, *SCANNING electron microscopy
Abstract

Abstract: The synergistic inhibitory action of cetylpyridinium chloride (CPC) and different halides on the corrosion of mild steel in 0.5 M H2SO4 has been investigated using electrochemical methods and scanning electron microscopy (SEM). Experimental results showed that the protection efficiency (P icor) of CPC improved in the presence of the different halides with different extents. Chemisorption was proposed from the trend of P icor and the values of . The synergism parameter is found to be greater than unity indicating that the enhanced P icor caused by the addition of the halides to the CPC is due to a co-operative adsorption of both species. [Copyright &y& Elsevier]

Published
2013
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36. Impact of SO2 poisoning of platinum nanoparticles modified glassy carbon electrode on oxygen reduction

Author

Awad, M.I., Saleh, M.M., and Ohsaka, T.

Subjects
*SULFUR dioxide, *CARBON electrodes, *CHEMICAL reduction, *NANOPARTICLES, *PLATINUM, *OXYGEN, *VOLTAMMETRY
Abstract

Abstract: An extraordinary recovery characteristic of Pt-nanoparticles from SO2 poisoning is introduced in this study. Platinum nanoparticles (nano-Pt) modified glassy carbon electrode (nano-Pt/GC) has been compared with polycrystalline platinum (poly-Pt) electrode towards SO2 poisoning. Two procedures of recovery of the poisoned electrodes were achieved by cycling the potential in the narrow potential range (NPR, 0–0.8V vs. Ag/AgCl/KCl (sat.)) and wide potential range (WPR, −0.2 to 1.3V). The extent of recovery was marked using oxygen reduction reaction (ORR) as a probing reaction. SO2 poisoning of the electrodes changed the mechanism of the oxygen reduction from the direct reduction to water to the stepwise reduction involving the formation of H2O2 as an intermediate, as indicated by the rotating ring-disk voltammetry. Using the WPR recovery procedure, it was found that two potential cycles were enough to recover 100% of the activity of the ORR on the nano-Pt/GC electrode. At the poly-Pt electrode, however, four potential cycles of the WPR caused only 79% in the current recovery, while the peak potential of the ORR was 130mV negatively shifted as compared with the fresh poly-Pt electrode. Interestingly, the NPR procedure at the nano-Pt/GC electrode was even more efficient in the recovery than the WPR procedure at the poly-Pt electrode. [Copyright &y& Elsevier]

Published
2011
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38. Global variation in postoperative mortality and complications after cancer surgery: a multicentre, prospective cohort study in 82 countries

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Stephen R Knight, Catherine A Shaw, Riinu Pius, Thomas M Drake, Lisa Norman, Adesoji O Ademuyiwa, Adewale O Adisa, Maria Lorena Aguilera, Sara W Al-Saqqa, Ibrahim Al-Slaibi, Aneel Bhangu, Bruce M Biccard, Peter Brocklehurst, Ainhoa Costas-Chavarri, Kathryn Chu, Anna Dare, Muhammed Elhadi, Cameron J Fairfield, J Edward Fitzgerald, Dhruv Ghosh, James Glasbey, Mark I. van Berge Henegouwen, J.C. Allen Ingabire, T Peter Kingham, Marie Carmela Lapitan, Ismaïl Lawani, Bettina Lieske, Richard Lilford, Janet Martin, Kenneth A McLean, Rachel Moore, Dion Morton, Dmitri Nepogodiev, Faustin Ntirenganya, Francesco Pata, Thomas Pinkney, Ahmad Uzair Qureshi, Antonio Ramos-De la Medina, Aya Riad, Hosni Khairy Salem, Joana Simões, Richard Spence, Neil Smart, Stephen Tabiri, Hannah Thomas, Thomas G Weiser, Malcolm West, John Whitaker, Ewen M Harrison, Arben Gjata, Maria Marta Modolo, Sebastian King, Erick Chan, Sayeda Nazmun Nahar, Ade Waterman, Dominique Vervoort, Alemayehu Ginbo Bedada, Bernardo De Azevedo, Ana Gabriela Figueiredo, Manol Sokolov, Venerand Barendegere, Gerald Ekwen, Arnav Agarwal, Qinyang Liu, Juan Camilo Correa, Kalisya Luc Malemo, Jacques Bake, Jakov Mihanovic, Kamila Kuncarová, Julius Orhalmi, Hosni Salem, Jyri Teras, Aristotelis Kechagias, Alexis P Arnaud, Judith Lindert, Vasileios Kalles, Maria-Lorena Aguilera-Arevalo, Gustavo Recinos, Zsolt Baranyai, Basant Kumar, Harish Neelamraju Lakshmi, Sanoop Koshy Zachariah, Philip Alexander, Sunil Kumar Venkatappa, C Pramesh, Radhian Amandito, Christina Fleming, Luca Ansaloni, Gianluca Pellino, Ahmed M. 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Aljadidi, Enas Saddouh, Randa Sharif, Aya Alabuzidi, AbdulMawlay Alwerfally, Sarra Aribi, Fatma Bibas, Taha Elfaituri, Yasmine Elhajjaji, Ala Khaled, Wegdan Khalil, Tesneem Layas, Enas Soula, Ahmed Tarek, Muad fathi khalleefah Abu hallalah, Hazem Abdelkarem Ahmed, Tagwa Alsharef, Abdulsalam Ali Ben Saoud, Tasnim El Gharmoul, Ahmed Elhadi, Safa Elrais, Abdulhalim Shebani, Heba Zarti, Asaid Zeiton, Marijus Ambrazevicius, Nerijus Kaselis, Migle Stakyte, Oleg Aliosin, Agne Cizauskaite, Sarunas Dailidenas, Vitalijus Eismontas, Migle Kybransiene, Vitalija Nutautiene, Narimantas Samalavicius, Dainius Simcikas, Algirdas Slepavicius, Albinas Tamosiunas, Nerijus Ubartas, Paulius Zeromskas, Saulius Bradulskis, Edvinas Dainius, Juozas Juocas, Egle Kubiliute, Juozas Kutkevicius, Aurimas Opolskis, Audrius Parseliunas, Andrejus Subocius, Egle Virbickaite, Diana Zuikyte, Algirdas Bogusevicius, Kristina Buzaite, Daiva Cepuliene, Ieva Cesleviciene, Vaidotas Cesna, Jolanta Gribauskaite, Povilas Ignatavicius, Mantas Jokubauskas, Monika Liugailaite, Ernest Margelis, Ruta Mazelyte, Lina Pankratjevaite, Matas Pažusis, Agne Rackeviciute, Justina Saladyte, Monika Škimelyte, Vygintas Šlenfuktas, Monika Sudeikyte, Algimantas Tamelis, Tomas Vanagas, Žygimantas Žumbakys, Aivaras Atkociunas, Audrius Dulskas, Justas Kuliavas, Justas Birutis, Sigitas Paškevicius, Mindaugas Šatkauskas, Donatas Danys, Matas Jakubauskas, Lina Jakubauskiene, Marius Kryzauskas, Vytautas Lipnickas, Gabija Makunaite, Fanjandrainy Rasoaherinomenjanahary, Herizo Rasolofonarivo, Luc Hervé Samison, Bitiel Banda, Vanessa Msosa, Ahmad Imran Ahmad Izzuddin, Andre Das, Ying Yee Gan, Tan Shong Sheng, Jia yng Siaw, Mohd Fadliyazid Ab Rahim, Dyg Zahratul Hamrak Abang Jamari, Nurfariza Che Husin, Muhd Yusairi Kamarulzaman, Yi Ping Lim, Nil Amri Mohamed Kamil, Mohd Razeen Mohd Hassan, Saidah Mohd Sahid, Johari Mustafa, Elaine Hui Been Ng, Wan Khamizar Wan Khazim, Ng Chang Ern, P.g. Lingeshan, Syariz Ezuan Sulaiman, Sue Ean Ang, Muhammad Navid Bin Mohamad Sithik, Yih Jeng Cheong, Mahadevan Deva Tata, Law Jia Xian, Aravinthan Kadravello, I-Ern Koh, Li-Yen Ng, Yuki Julius Ng We Yong, Kandasami Palayan, Chi Xuan Sam, Phuah Siow Jin, Jeremy Tan Ern Hwei, Yita Tang, Alvin Zubin Ter, Michael Pak-Kai Wong, Andee Dzulkarnaen Zakaria, Zaidi Zakaria, Fitjerald Henry, Thyivya Kalaiselvan, Muhammad Fairuz Shah Abd Karim, Mohamed Rezal Abdul Aziz, Nora Abdul Aziz, Tak Loon Khong, Peng Choong Lau, Hiong Chin Lim, April Camilla Roslani, Jonathan Chen Ken Seak, Sui-Weng Wong, Lai Fen Wong, Leow Yeen Chin, Mercy Chinemerem Anyanwu, Zachary Busuttil, Thomas Calleja, Kurt Lee Chircop, Ruth Cutajar, Andrew Michael Dimech, Joseph Galea, Kiara Gascon Perai, Ruth Gatt, Lisa Kelman, Elizabeth Micallef, Favour Nwolu, Kim Sammut, Joanna Thompson, Sean Warwicker, Matthew Zammit, Fernando Cordera, Efraín Cruz González, Jorge Sánchez-García, Francisco José Barbosa Camacho, Francisco Javier Barrera López, Carlos Jose Zuloaga Fernandez del Valle, Eric Acosta, Iván Romarico González Espinoza, Perla Moreno, Ana Olivia Cortes-Flores, Clotilde Fuentes Orozco, Alejandro Gonzalez Ojeda, Samantha Corro Díaz González, Laura Martinez, Bonifacio Mosqueda Amador, Armando Novoa, Dennet Arturo Olazo Espejo, Alejandro Jimenez, Federico Lopez Rosales, Elva Gabriela Vanoye, Luis Alberto Garcia Gonzalez, Roberto Carlos Miranda-Ackerman, Manuel Solano-Genesta, Alethia Alvarez-Cano, Hector Hugo Romero-Garza, Heriberto Medina-Franco, Lorelí Mejía-Fernández, Noel Salgado-Nesme, Omar Vergara-Fernandez, Guadalupe Montserrat Gutiérrez-Mota, Francisco Xavier Hernandez Vera, Anabella Llantada Lopez, Gilberto Morgan Villela, Felipe de Jesus Ramirez Padilla, Walezka Tapia Marin, Mónica Martínez Maldonado, Ramses Sánchez Suárez, José Manuel Troche, Chaymae Benyaiche, Oumaima Outani, Souadka Amine, Amine Benkabbou, Anass Mohammed Majbar, Raouf Mohsine, Ali Rafik, Thida Oung, Moe Moe Tin, Philipp Plarre, Anna Alberga, Nina Sluiter, Jurriaan Tuynman, Robin Blok, Didem Cömert, Roel Hompes, Marianne Kalff, Merel Elisabeth Stellingwerf, Pieter Tanis, Mark van Berge Henegouwen, Elise Maria van Praag, Daan Wisselink, Michael Gerhards, Josephine Lopes Cardozo, Emma Westerduin, Joske de Jonge, Aaw van Geloven, Kaz van Schilt, Frank den Boer, Simone Stoots, Stijn Vlek, Jamie Adams, Ibrahim S. Al-Busaidi, Gabrielle Budd, Seung il Choi, Michael Jen Jie Chu, Anurag Ganugapati, Lucy McKinstry, Rebecca Pascoe, Simon Richards, Kenrick Rosser, Annie Stevenson, Rebecca White, Shebani Farik, Jin Kwun, Ahmed Murad, Sarah Cowan, Timothy Hall, Michael Hayton, Laminou Malam Sani, Souleymane Oumarou Garba, Ibrahim Amadou Magagi, Oumarou Habou, Halima Aliyu, Muhammad Daniyan, Tunde T. Sholadoye, Lawal Abdullahi, Lofty-John Anyanwu, Aminu Mohammad Mohammad, Abubakar Bala Muhammad, Abdurrahman Abba Sheshe, Ibrahim Suleiman, Alaba Adesina, Ajibola Awolowo, Clement Onuoha, Omotayo Salami, Ogechukwu Taiwo, Agboola Taiwo, Stephen Kache, Jerry Godfrey Makama, Danjuma Sale, Olajide Abiola, Akinlabi Ajao, Anthony Ajiboye, Amarachukwu Etonyeaku, Julius Olaogun, Ademola Adebanjo, Opeoluwa Adesanya, Michael Olatunji Afolayan, Olanrewaju Balogun, Ayomide Makanjuola, Samuel Nwokocha, Rufus Wale Ojewola, Thomas Olagboyega Olajide, Adewale Aderounmu, Abdul-Rashid Adesunkanmi, Augustine Agbakwuru, Adeleke Akeem Aderogba, Olusegun Isaac Alatise, Olukayode Arowolo, Oladejo Lawal, Tajudeen Mohammed, Chinedu Ndegbu, Olalekan Olasehinde, Funmilola Wuraola, Akinbolaji Akinkuolie, Arinzechukwu Mosanya, Omobolaji Ayandipo, Peter Elemile, Taiwo Akeem Lawal, Samuel Ali SANI, Stephen Garba, Rebecca Hauwa SANI, Samson Olori, Henry Onyebuashi, Ifeanyi Umoke, Adedire Adenuga, Ademola Adeyeye, Olufemi Habeeb, Bashir Lawal, Abdulrasheed Nasir, Eirik Kjus Aahlin, Didrik Kjønås, Elisabeth Myrseth, Jibran Abbasy, Abdul Alvi, Omair Saleem, Asma Afzal, Anam Nazir, Muhammad Farooq, Ayesha Liaqat, Syed Asghar Naqi, Ali Raza, Muzna Sarfraz, Muhammad Sarwar, Muntaha Banglani, Ambreen Munir, Rahmat Sehrish, Bushra Ayub, Raza Sayyed, Amna Altaf, Saima Ayub, Komal Saeed, Bilal Syed, Sana Amir Akbar, Abdul Wahid Anwer, Ruqayya Naheed Khan, Amina Iqbal Khan, Shahid Khattak, Sameen Mohtasham, Muhammad Asad Parvaiz, Aamir Ali Syed, Abdul Basit Ansari, Noman Shahzad, Tanwir Khaliq, Isbah Rashid, Shahzad Hussain Waqar, Hasan Abu Al-saleem, Amjad Abu Alqumboz, Mohammad Alqadi, Adham Amro, Rawan Assa, Eman Awesat, Rawan Ayyad, Mohammed Hammad, Ayat Haymony, Bassel Hijazi, Bara Hmeidat, Rowaa Lahaseh, Aseel Qawasmi, Alaa Rajabi, Mohammed Shehada, Sundus Shkokani, Yasmine Yaghi, Nadine Yaghi, Mohammad AlZohour, Mohammad Farid, Yousef Mahmoud Habes, Wesam Juba, Yanal Nubani, Abdelrahman Rabee, Mohammad Sa'deh, Saeed Abed, Iyad Al basos, Mohammad Alswerki, Dina Ashour, Israa Awad, Samar Diab, Alaa El Jamassi, Sahar El-Kahlout, Somaya Elhout, Ahmed N K Hajjaj, Doaa Hasanain, Baraa Nabil hajjaj, Mohammed Obaid, Eman Saikaly, Ahmed Salhi, Hiba Al-Tammam, Murad Almasri, Muath Baniowda, Doha Beshtawi, Ali Horoub, Rami Misk, Bayan Mohammad, Rami Qasrawi, Tasnim Sholi, Samar Abu-Nimeh, Abrar Abu-srour, Sadi A. Abukhalaf, Samer Adawi, Barah Alsalameh, Kholoud Ayesh, Muawiyah Elqadi, Ahmad Hammouri, Fatima Karim Mustafa, Natalie Marzouqa, Shatha Melhem, Dima Miqdad, Balqees Mohamad, Mhammed Rawhi, Ayman B. Abu Ahammala, Ahmed Abu Ataya, Israa Abu Jayyab, Samar Al-Shwaikh, Othman Alagha, Mohammed Alasttal, Haneen Awadallah, Mahmood Elblbessy, Jehad Fares, Akram Jarbou, Ibtisam Mahfouz, Moath A. Albahnasawi, Asmaa' Abo mahadi, Hasan Abuelhatal, Ayham Abuelqomboz, Abdelrahman Almoqayyad, Abdallah Alwali, Reem Balaawi, Mahmoud Hamouda, Mohammed Humeid, Abdullah Jedyan, Tasneem Mahmoud Abu hamam, Ghadeer Matar, Ali Salem, Tahani Samra, Nureddin Shaheen, Karam Shihada, Ayoob A.Nemer, Mahmoud Abu Al Amrain, Abdulwhhab Abu Alamrain, Najlaa Abu Jamie, Mohammed R. Abu-Rous, Nada Alfarra, Mohammed AlTaweel, Noor Alwhaidi, Ramadan Hamed, Bader Saqqa, Ahmad Shaheen, Dana Aljaber, Loay Aljaberi, Malak Alwaheidi, Assef Jawaada, Hani Khaldi, Rami Qahoush, Jalil Qari, Rana Saadeh, Ahlam Salim, Aseel Yacoub, Abbas Abbas, Rana Abu shua`ib, Baraa Abu Zainah, Mahmoud AbuSirrees, Basheer Babaa, Ola Barhoush, Asef Belal qadomi, Laith Daraghmeh, Reema Haji, Alaa Khatatbeh, Lana Khatib, Salsabeel Qarariah, Yara Quzmar, Khalil Safadi, Roqaya Salameh, Mohammad Hassan, Shifaa Herzallah, Loai Massad, Ahmed Nazzal, Ranin Nazzal, Dennis Escobar, Gustavo Miguel Machain V, Agustin Rodriguez Gonzalez, Jorge Emerson Chachaima Mar, Nathaly Olga Chinchihualpa Paredes, Vicente Cuba, Walter Lopez, Maria Milagros Niquen Jimenez, Nestor Alberto Sanchez Bartra, Olenka Sapallanay Ojeda, Diego Sequeiros, Andrea Toscano Pacheco, María Vergara, Sol Abarca, Rodrigo Alcorta, Giuliano Borda-Luque, Ivan Edward Eusebio Zegarra, Claudia Luján López, Mirella Marrufo, Cinthya Mogrovejo, Andrea Nomura, Yamile Rodríguez Angeles, Maitza Rosario Vidal Meza, Gabriela Zavala, José Neiser Castillo Arrascue, Jomara Caroline Hidrogo Cabrera, José Julio Mariano Larrea vera, Miguel Osorio, Edgar Alcides Ylatoma Díaz, Mark Anthony Fontanilla, Joseph Roy Fuentes, Anna Leah Salazar, Genieve Dominguez, Marc Paul Lopez, Shiela Macalindong, Mark Augustine Onglao, Arjel Ramirez, Marie Dione Sacdalan, Mayou Martin Tampo, Gemma Leonora Uy, Jeremiah Mangahas, Kenneth Yabut, Joannes Paul Cañete, Bernalynn Eris Cansana, Ernes John Castro, Maria Kaiserin Lipana, Manuel Francisco Roxas, Vlu Jean Zara, Maciej Chrol, Paula Franczak, Michal Orlowski, Piotr Budzynski, Andrzej Budzynski, Pawel Bury, Agata Czerwinska, Jadwiga Dworak, Jacek Dziedzic, Michal Kisielewski, Jan Kulawik, Anna Lasek, Piotr Malczak, Marcin Migaczewski, Michal Pedziwiatr, Magdalena Pisarska, Dorota Radkowiak, Mateusz Rubinkiewicz, Anna Rzepa, Tomasz Skoczylas, Maciej Stanek, Katarzyna Truszkiewicz, Mateusz Wierdak, Marek Winiarski, Piotr Zarzycki, Anna Zub-Pokrowiecka, Piotr Kowalewski, Rafal Roszkowski, Maciej Waledziak, Miguel Tomé, Sara Patrocinio, Ines Guerreiro, Filipe Almeida, Xavier de Sousa, Nuno Monteiro, Maria Teresa Costa Santos, Daniela de Oliveira, Marta Lopes Serra, Daniela Morgado, Christian Neves, Ana Carolina Oliveira, Alice Pimentel, Sofia Silva, Márcia Carvalho, Lúcia Carvalho, Joana Magalhães, Leonor Matos, Tânia Monteiro, Carlota Ramos, Vanessa Santos, José Barbosa, Jose Costa-Maia, Vítor Devezas, Ana Fareleira, Cristina Fernandes, Diana Gonçalves, Henrique Mora, Marina Morais, Fabiana Silva de Sousa, Sara Catarino Santos, Ana Logrado, André Tojal, Edgar Amorim, Miguel F. Cunha, Ana Fazenda, João Pedro Melo Neves, Inês Isabel Sampaio da Nóvoa Gomes Miguel, Diogo Veiga, José Azevedo, Hugo Cardoso Louro, Mariana Leite, Maria Bairos Menezes, Bárbara Gama, Diana Brito, Marta Cristina Cruz Martins, André Graça e Magalhães, Ana Catarina Longras, Rita Lourenço, Diana Matos, Luis Castro, Filipa Policarpo, Joana Romano, Cristina Monteiro, Diogo Pinto, Marina Duarte, Sónia Fortuna Martins, Mariline Oliveira, Diogo Galvão, Lisandra Martins, Anaisa Silva, Viorel Taranu, Bárbara Vieira, Jessica Neves, Simone Oliveira, Hugo Ribeiro, Margarida Cinza, Rosa Felix, Arnaldo Machado, Joana Oliveira, Joana Patrício, Rita Pedroso de Lima, Mário Pereira, Miguel Rocha Melo, Cristina Velez, Alberto Abreu da Silva, Mariana Claro, Daniel Costa Santos, Andreia Ferreira, Hugo Capote, Daniela Rosado, Filipa Taré, Oriana Nogueira, Miguel Ângelo, José Miguel Baiao, Andreia Guimarães, João Marques, Miguel Nico Albano, Marta Silva, Ana Valente da Costa, Teresa Vieira Caroço, Sara Almeida Braga, Ines Capunge, Marta Fragoso, João Guimarães, Bruno Pinto, João Ribeiro, Miguel Angel, Guilherme Fialho, Monica Guerrero, Filipa Campos Costa, Diogo Cardoso, Vasco Cardoso, Magda Alves, Inês Estalagem, Tiago Louro, Cláudia Marques, Rita Martelo, Miguel Morgado, Rita Canotilho, Ana Margarida Correia, Pedro Martins, Mariana Peyroteo, João Gomes, Rita Monteiro, Manuela Romano, Daniela Macedo Alves, Rita Peixoto, Catarina Quintela, Maria João Jervis, Débora Melo, André Pacheco, Valter Paixão, Vera Pedro, Joana Pimenta, João Pimenta de Castro, Ana Rocha, Mircea Beuran, Cezar Ciubotaru, Bogdan Diaconescu, Sorin Hostiuc, Ionut Negoi, Bogdan Stoica, NA NA, Evgeny Anokhin, Georgy Kuznetsov, Giorgi Oganezov, Fedor Paramzin, Ekaterina Romanova, Valeryan Rutkovskii, Vasilii Rutkovskii, Mikhail Shushval, Mikhail Zabiyaka, Khasan Dzhumabaev, Valerii Ivanov, Zaman Mamedli, Sergey Achkasov, Artem Balkarov, Elnur Nabiev, Marat Nagudov, Evgeny Rybakov, Karina Saifutdinova, Oleg Sushkov, Lule Joseph, Isaac Ndayishimiye, Ntirenganya Faustin, Alphonse Zeta Mutabazi, Jean Paul Mvukiyehe, Vizir J.P Nsengimana, Carine Uwakunda, Mohammad Monir Abbas, Nouf Akeel, Murad Aljiffry, Kholoud Awaji, Ali Farsi, Ghader Jamjoum, Ahmad Khoja, Ashraf Maghrabi, Nadim Malibary, Mohammed Nassif, Abdulaziz Saleem, Abdullah Sultan, Wail Tashkandi, Hanaa Tashkandi, Nora Trabulsi, Mouhamadou Bachir Ba, Adja Coumba Diallo, Abdourahmane Ndong, Vladica Cuk, Uroš Jankovic, Sharon Zhiling Koh, Frederick Koh, Kuok Chung Lee, Kai Yin Lee, Sean Lee, Wei Qi Leong, Su Ann Lui, Prajwala Prakash, Jan Grosek, Gregor Norcic, Ales Tomazic, Nicolas Fitchat, Robert Jaich, Devorah Wineberg, Modise Zacharia Koto, Daniella Baiocchi, Damian Clarke, Christina Johanna Steenkamp, Sharon Bannister, Adam Boutall, Galya Chinnery, Anna Coccia, Angela Dell, Parveen Karjiker, Christo Kloppers, Nicholas Loxton, Tumi Mabogoane, Francois Malherbe, Eugenio Panieri, Shreya Rayamajhi, Tirsa van Wyngaard, Claire Warden, T E Madiba, Nivashen Pillay, Savannah Brooks, Charlise Kruger, Lisa Hannah Van Der Merwe, Ferhana Gool, Maahir Kariem, Heather Bougard, Nazmie Kariem, Fazlin Noor, Reantha Pillay, Leandi Steynfaardt, Lucía González González, José Miguel Marín Santos, Paula Martín-Borregón, Javier Martínez Caballero, Cristina Nevado García, Pastora Rodriguez Fraga, Gonzalo De Castro Parga, Maria Pilar Fernández Veiga, Lucía Garrido López, Hugo Infante Pino, Irene Lages Cal, Marta López Otero, Manuel Nogueira Sixto, Marta Paniagua García Señorans, Laura Rodríguez Fernández, Alejandro Ruano Poblador, Erika Rufo Crespo, Raquel Sanchez-Santos, Vincenzo Vigorita, Ester Alonso Batanero, Dorisme Asnel, Isabel Cifrian Canales, Elisa Contreras Saiz, Irene De Santiago Alvarez, Tamara Díaz Vico, Sebastian Fernandez Arias, Daniel Fernández Martínez, Carmen García Bernardo, Luis Joaquín García Flórez, Carmen Garcia Gutierrez, Manuel García Munar, Carlos Alberto Márquez Zorrilla Molina, Marta Merayo, José Luis Michi Campos, Maria Moreno Gijon, Jorge L. Otero-Diez, Jose Luis Rodicio Miravalles, Lorena Solar-Garcia, Aida Suárez Sánchez, Nuria Truan, Cristina Alejandre Villalobos, Yurena Caballero Díaz, Marta Jimenez, Dacil Montesdeoca, Antonio Navarro-Sánchez, Victor Vega, Juan Beltrán de Heredia, Zahira Gómez, Carlos Jezieniecki, Ana Patricia Legido Morán, Mario Montes-Manrique, Mario Rodriguez-Lopez, María Ruiz Soriano, Jeancarlos Trujillo Díaz, Andrea Vazquez Fernandez, Nuria Argudo, Miguel Pera, Laia Torrent Jansà, Melody García Domínguez, Ignacio Goded, Marta Roldón Golet, Issa Talal El-Abur, Alejandra Utrilla Fornals, Vanesa Zambrana Campos, Maria Del Mar Aguilar Martinez, Marina Bosch, Luis García-Catalá, Luis Sánchez-Guillén, Eva Artigau, Nuria Gomez Romeu, David Julià Bergkvist, Beatriz Espina Perez, Olga Morató, Carles Olona, Beatriz Diéguez, Alexander Forero-Torres, Manuel Losada, Segundo Gomez-Abril, Paula Gonzálvez, Rosario Martinez, Sergio Navarro Martínez, Carmen Payá-Llorente, Álvaro Pérez Rubio, Sandra Santarrufina Martinez, Juan Carlos Sebastián Tomás, Ramon Trullenque Juan, Alberto Gegúndez Simón, Paloma Maté, Maria Isabel Prieto-Nieto, Ines Rubio-Perez, Aitor Urbieta, Marina Vicario Bravo, David Abelló, Matteo Frasson, Alvaro Garcia-Granero, Alfredo Abad Gurumeta, Ane Abad-Motos, Elena Lucena-de Pablo, Beatriz Nozal, Javier Ripollés-Melchor, Rut Salvachúa, Esther Ferrero, Luis Garcia-Sancho Tellez, Antonio L. Picardo, Jose Alberto Rojo López, Laura Patricia Zorrilla Matilla, Carmen Cagigas Fernandez, Sonia Castanedo Bezanilla, José Estevez Tesouro, Maria Jose Fernandez-Diaz, Juan García Cardo, Marcos Gomez Ruiz, Erik Gonzalez-Tolaretxipi, Jaime Jimeno Fraile, Cristobal Poch, Montserrat Rodriguez-Aguirre, Noemí Troche Pesqueira, Maria Soledad Trugeda-Carrera, Javier de la Torre, Ruth Blanco-Colino, Eloy Espin-Basany, Martin Espinosa-Bravo, Clara Morales Comas, Eduardo Reyes Afonso, Joaquín Rivero Déniz, Christian Siso Raber, Mireia Verdaguer Tremolosa, Pramodh Chandrasinghe, Sumudu Kumarage, Nimeshi Wijekoon Arachchilage, Ahmed Abdalla Ahmed Elkamel, Mohammed A. Adam, Nina Blomme, Anders Thorell, Fredrik Wogensen, Andreas Älgå, Dhirar Ansarei, Fuat Celebioglu, Göran Heinius, Linda Nigard, Emil Pieniowski, Sandra Ahlqvist, Ida Björklund, Andreas Frånberg, Martina Håkansson, Karin Adamo, Oskar Franklin, Malin Sund, Rebecca Wiberg, Yvette Andersson, Abbas Chabok, Maziar Nikberg, Alexander Kugelberg, Claudia Canonica, Dimitrios Christoforidis, Fabrizio Fasolini, Paolo Gaffuri, Mauro Giuliani, Francesco Meani, Sotirios Georgios Popeskou, Silvia Pozza, Wiebke Wandschneider, Lorenz Peterer, Lukas Werner Widmer, Bernd Zimmermann, Panagiotis Bakoleas, Iris Chanousi, Lydia Charalampidou, Lukasz Filip Grochola, Franziska Heid, Sotirios Ntaoulas, Michail Outos, Georgios Peros, Hanna Podolska-Skoczek, Katharina Beate Reinisch, Christian Zielasek, Nicolas Demartines, Jérôme Gilgien, Amaniel Kefleyesus, Pénélope St-Amour, Arnaud Toussaint, Maryam Alhimyar, Bayan Alsaid, Amr Alyafi, Ahmad Alkhaledi, Basel Kouz, Ahmad Omarain, Yusra Al-Sabbagh, Haya Alkhatib, Samer Sara, Ahmad Alhaj, Aghyad Danial, Lama Kadoura, Sarah Maa Albared, Yamen Monawar, Louei Nahas, Barook Abd, Ahmad Saad, Habib Wakkaf, Hatem Bouzaiene, Montassar Ghalleb, Elif Akaydin, Ata Cem Akbaba, Onur Atakul, Ege Baltaci, Sevval Besli, Gökçen Burgu, Ulukan Cenal, Cansu de Muijnck, Hasan Can Demirkaya, Alper Dogruoz, Zeynep Ipek Gezer, Yasemin Gündogdu, Merve Kara, Hasan Kürsad Korkmaz, Gökalp Kagan Kurtoglu, Volkan Ozben, Berk Baris Ozmen, Ahmet Murat Pektas, Eda Kübra Sel, Nilüfer Yenidünya, Fuat Baris Bengur, Berke Mustafa Oral, Tahir Koray Yozgatli, Seymur Abdullayev, Mehmet Emin Gunes, Nuri Alper Sahbaz, Tuba Banaz, Kübra Kargici, Omer Faruk Kuyumcu, Erkan Yanikoglu, Merve Yesilsancak, Duygu Yilmaz, Melik Kagan Aktas, Ahmet Rencuzogullari, Arda Isik, Sezai Leventoglu, Ali Yalçinkaya, Osman Yüksel, Mustafa U Kalayci, Yasin Kara, Inanc Samil Sarici, Alp Akin, Gökçe nur Alemdag, Ekin Arslan, Bahadir Emre Baki, Muhammed Selim Bodur, Adnan Calik, Bahar Candas Altinbas, Irem Cihanyurdu, Oguz Erkul, Burak Gül, Ali Guner, Beyza Köse, Anil Semiz, Sule Sevim, Serkan Tayar, Kadir Tomas, Ozan yavuz Tüfek, Serdar Türkyilmaz, Mehmet Ulusahin, Arif Usta, Reyyan Yildirim, Sertaç Ata Güler, Ozan Can Tatar, Ecenur Varol, Busenur Kirimtay, Muhammed Uysal, Alp Yildiz, Emin Kose, Ahmet Burak Ciftci, Elif Çolak, Huseyin Eraslan, Gultekin Ozan Kucuk, Kürsat Yemez, Herman Lule, Mumbere Bienfait, Emmanuel Bua, Noella Okalany, Maksym Basarab, Oleksii Bielosludtsev, Kateryna Kolhanova, Kateryna Perepelytsia, Kateryna Romanukha, Dmytro Savenkov, Stanislav Siryi, Maksym Tereshchenko, Nezamai Viacheslav, Anton Volovetskyi, Andrey Kebkalo, Yegor Tryliskyy, Volodimir Tyselskiy, Eilidh Bruce, Bing Lun Chow, Emma Iddles, Sarah McGuckin, Nicola Newall, George Ramsay, Parivrudh Sharma, Caitlin Stewart, Jeremy Wong, Abdul Badran, Michael Bath, Fanny Belais, Eman Butt, Kaustuv Joshi, Milan Kapur, Mike Shaw, Adam Townson, Christopher Yee Khang Williams, Timothy Gray, Robert Greig, Mansoor Husain, Elspeth Murray, Ahmed Mustafa, Ashar Asif, Arya Gokul, Max Shah, Mabel Temisanren Akitikori, Alexandros Charalabopoulos, Sophie Davidson, Sinead McNally, Shamil Rupani, Fatema Juma, Sarah Catherine Mills, Laura Muirhead, Kate Sellars, Una Walsh, Oliver Warren, Alice Chambers, Richard Hunt, Stephen Boyce, Hannah Cornwall, Isabel Tol, Eleftherios Orestis Argyriou, Nicola Eardley, Meical Povey, Joanna M S Aithie, Ahmer Irfan, Mari-Claire McGuigan, Robert Starr, Craig Russell Warren, Jess Archibald, Georgia Kirby, Ivan Kisyov, Chun Kheng Khoo, Rachel Lee, Dana Photiou, Rowan Davis, Uday Prasad, P Zichu Yang, Jonathan Bird, Edmund Leung, Virginia Summerour, Chelise Currow, Jianshen Kiam, Gerald Jack Soon Tan, Anitha Muthusami, Ibifunke Pegba-Otemolu, Tomas Urbonas, Joseph Nunoo-Mensah, Edgaras Smolskas, Alex Boddy, Gianpiero Gravante, David Hunter, David Andrew, Amanda Koh, Amari Thompson, Lawrence Adams, Hollie A Clements, Kasun De Silva, Ogbonnia Ekpete, Seraj Haque, Scott Henderson, Bilal Ibrahim, Thummini Jayasinghe, Jennifer Livie, Keir Mailley, Gopikrishnan Nair, Daniel Tan, Caitlin Baggaley, Aleksander Dawidziuk, Bartosz Szyszka, Charlotte Barter, Nirav Gandhi, Karen Hassell, Samantha Hitchin, Jennett Kelsall, Eva Nagy, Ashrafun Nessa, Lisa Whisker, Fady Yanni, Mahmoud Ali, Deeksha Arora, Sunanda Hediwattege, Navam Kumarasinghe, Munir Rathore, Athula Tennakoon, Syed Mustafa Ali Ahmad, Oreoluwa Bajomo, Fahema Nadira, Valerio Celentano, Ewen Griffiths, Rama Santhosh Karri, Jason Kei Chak Mak, Michelle Pipe, Muhammad Iqbal Bhatti, Mohamed Rabie, Connor Boyle, David Hamilton, Aishath Mihuna, James Chean Khun Ng, Gary Nicholson, Agata Oliwa, Robert Pearson, Anna Rose, Shun Qi Yong, Catherine Boereboom, Michael Hanna, Catherine Walter, Thomas Samuel Greensmith, Rachel Mitchell, Eimear Monaghan, James Crawford, Susan Moug, James Blackwell, Hannah Boyd-Carson, Philip Herrod, Omar Al-Allaf, Miriam Beattie, Cameron Bullock, Shivang Burman, Gemma Clark, Nicolas Flamey, Oliver Flannery, Alexander Harding, Ben Kodiatt, Samuel Lawday, Shivani Mahapatra, Navin Mukundu Nagesh, Michael Ng, Dupinderjit Rye, Andrel Yoong, Laura Clark, Chris Deans, Monisha Edirisooriya, Emma Victoria Carrington, Tsz Lun Ernest Wong, Baasil Yusuf, Carla Chamberlain, Kathryn Duke, Elizabeth Kmiotek, Azel Botes, Natalie Condie, Timothy Schrire, Reena Shah, Iolo Thomas-Jones, Charlotte Yates, Natasha Anthony, Edward Matthews, Kapil Sahnan, James Tankel, Sally Tucker, Jasmine Winter Beatty, Paul Ziprin, William Duggan, Anastasia Kantartzi, Shruthi Sridhar, Rachel Alys Khaw, Prakhar Srivastava, Charlotte Underwood, Homero Alves do Canto Brum, Sharat Chopra, Laura Davis, Rebecca Hughes, Joshua Tulley, Justin Alberts, Thomas Athisayaraj, Mojolaoluwa Olugbemi, Kasim Ahmad, Claudia Chan, Gavin Chapman, Hannah Fleming, Benjamin Fox, Julia Grewar, Kate Hulse, Duncan Rutherford, Mackay Sinead, Scott Smith, Doug Speake, Peter G Vaughan-Shaw, Natasha Christodoulides, Simrit 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A., Abu shua'ib R., Abu Zainah B., AbuSirrees M., Babaa B., Barhoush O., Belal qadomi A., Daraghmeh L., Haji R., Khatatbeh A., Khatib L., Qarariah S., Quzmar Y., Safadi K., Salameh R., Hassan M., Herzallah S., Massad L., Nazzal A., Nazzal R., Escobar D., Machain V G.M., Rodriguez Gonzalez A., Chachaima Mar J.E., Chinchihualpa Paredes N.O., Cuba V., Lopez W., Niquen Jimenez M.M., Sanchez Bartra N.A., Sapallanay Ojeda O., Sequeiros D., Toscano Pacheco A., Vergara M., Abarca S., Alcorta R., Borda-Luque G., Eusebio Zegarra I.E., Lujan Lopez C., Marrufo M., Mogrovejo C., Nomura A., Rodriguez Angeles Y., Vidal Meza M.R., Zavala G., Castillo Arrascue J.N., Hidrogo Cabrera J.C., Larrea vera J.J.M., Osorio M., Ylatoma Diaz E.A., Fontanilla M.A., Fuentes J.R., Salazar A.L., Dominguez G., Lopez M.P., Macalindong S., Onglao M.A., Ramirez A., Sacdalan M.D., Tampo M.M., Uy G.L., Mangahas J., Yabut K., Canete J.P., Cansana B.E., Castro E.J., Lipana M.K., Roxas M.F., Zara V.J., Chrol M., Franczak P., 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Adam M., Blomme N., Thorell A., Wogensen F., Alga A., Ansarei D., Celebioglu F., Heinius G., Nigard L., Pieniowski E., Ahlqvist S., Bjorklund I., Franberg A., Hakansson M., Adamo K., Franklin O., Sund M., Wiberg R., Andersson Y., Chabok A., Nikberg M., Kugelberg A., Canonica C., Christoforidis D., Fasolini F., Gaffuri P., Giuliani M., Meani F., Popeskou S.G., Pozza S., Wandschneider W., Peterer L., Widmer L.W., Zimmermann B., Bakoleas P., Chanousi I., Charalampidou L., Grochola L.F., Heid F., Ntaoulas S., Outos M., Peros G., Podolska-Skoczek H., Reinisch K.B., Zielasek C., Demartines N., Gilgien J., Kefleyesus A., St-Amour P., Toussaint A., Alhimyar M., Alsaid B., Alyafi A., Alkhaledi A., Kouz B., Omarain A., Al-Sabbagh Y., Alkhatib H., Sara S., Alhaj A., Danial A., Kadoura L., Maa Albared S., Monawar Y., Nahas L., Abd B., Saad A., Wakkaf H., Bouzaiene H., Ghalleb M., Akaydin E., Akbaba A.C., Atakul O., Baltaci E., Besli S., Burgu G., Cenal U., de Muijnck C., Demirkaya H.C., Dogruoz A., Gezer Z.I., Gundogdu Y., Kara M., Korkmaz H.K., Kurtoglu G.K., Ozben V., Ozmen B.B., Pektas A.M., Sel E.K., Yenidunya N., Bengur F.B., Oral B.M., Yozgatli T.K., Abdullayev S., Gunes M.E., Sahbaz N.A., Banaz T., Kargici K., Kuyumcu O.F., Yanikoglu E., Yesilsancak M., Yilmaz D., Aktas M.K., Rencuzogullari A., Isik A., Leventoglu S., Yalcinkaya A., Yuksel O., Kalayci M.U., Kara Y., Sarici I.S., Akin A., Alemdag G.N., Arslan E., Baki B.E., Bodur M.S., Calik A., Candas Altinbas B., Cihanyurdu I., Erkul O., Gul B., Guner A., Kose B., Semiz A., Sevim S., Tayar S., Tomas K., Tufek O.Y., Turkyilmaz S., Ulusahin M., Usta A., Yildirim R., Guler S.A., Tatar O.C., Varol E., Kirimtay B., Uysal M., Yildiz A., Kose E., Ciftci A.B., Colak E., Eraslan H., Kucuk G.O., Yemez K., Lule H., Bienfait M., Bua E., Okalany N., Basarab M., Bielosludtsev O., Kolhanova K., Perepelytsia K., Romanukha K., Savenkov D., Siryi S., Tereshchenko M., Viacheslav N., Volovetskyi A., Kebkalo A., Tryliskyy Y., Tyselskiy V., Bruce E., Chow B.L., Iddles E., McGuckin S., Newall N., Ramsay G., Sharma P., Stewart C., Wong J., Badran A., Bath M., Belais F., Butt E., Joshi K., Kapur M., Shaw M., Townson A., Williams C.Y.K., Gray T., Greig R., Husain M., Murray E., Mustafa A., Asif A., Gokul A., Shah M., Akitikori M.T., Charalabopoulos A., Davidson S., McNally S., Rupani S., Juma F., Mills S.C., Muirhead L., Sellars K., Walsh U., Warren O., Chambers A., Hunt R., Boyce S., Cornwall H., Tol I., Argyriou E.O., Eardley N., Povey M., Aithie J.M.S., Irfan A., McGuigan M.-C., Starr R., Warren C.R., Archibald J., Kirby G., Kisyov I., Khoo C.K., Lee R., Photiou D., Davis R., Prasad U., Yang P.Z., Bird J., Leung E., Summerour V., Currow C., Kiam J., Tan G.J.S., Muthusami A., Pegba-Otemolu I., Urbonas T., Nunoo-Mensah J., Smolskas E., Boddy A., Gravante G., Hunter D., Andrew D., Koh A., Thompson A., Adams L., Clements H.A., De Silva K., Ekpete O., Haque S., Henderson S., Ibrahim B., Jayasinghe T., Livie J., Mailley K., Nair G., Tan D., Baggaley C., Dawidziuk A., Szyszka B., Barter C., Gandhi N., Hassell K., Hitchin S., Kelsall J., Nagy E., Nessa A., Whisker L., Yanni F., Ali M., Arora D., Hediwattege S., Kumarasinghe N., Rathore M., Tennakoon A., Ali Ahmad S.M., Bajomo O., Nadira F., Celentano V., Griffiths E., Karri R.S., Mak J.K.C., Pipe M., Bhatti M.I., Rabie M., Boyle C., Hamilton D., Mihuna A., Ng J.C.K., Nicholson G., Oliwa A., Pearson R., Rose A., Yong S.Q., Boereboom C., Hanna M., Walter C., Greensmith T.S., Mitchell R., Monaghan E., Crawford J., Moug S., Blackwell J., Boyd-Carson H., Herrod P., Al-Allaf O., Beattie M., Bullock C., Burman S., Clark G., Flamey N., Flannery O., Harding A., Kodiatt B., Lawday S., Mahapatra S., Mukundu Nagesh N., Ng M., Rye D., Yoong A., Clark L., Deans C., Edirisooriya M., Carrington E.V., Wong T.L.E., Yusuf B., Chamberlain C., Duke K., Kmiotek E., Botes A., Condie N., Schrire T., Shah R., Thomas-Jones I., Yates C., Anthony N., Matthews E., Sahnan K., Tankel J., Tucker S., Winter Beatty J., Ziprin P., Duggan W., Kantartzi A., Sridhar S., Khaw R.A., Srivastava P., Underwood C., Alves do Canto Brum H., Chopra S., Davis L., Hughes R., Tulley J., Alberts J., Athisayaraj T., Olugbemi M., Ahmad K., Chan C., Chapman G., Fleming H., Fox B., Grewar J., Hulse K., Rutherford D., Sinead M., Speake D., Vaughan-Shaw P.G., Christodoulides N., Kudhail S., Welch M., Husaini S.M., Lambracos S., Anyanwu C., Suresh R., Thomas J.S., Gleeson E., Platoff R., Saif A., Enumah Z., Etchill E., Gabre-Kidan A., Bernstein M., Carrano F.M., Connors J., Lynn P., Melis M., Newman E., Foster D.S., Perrone K., Titan A., Ahmad S., Bafford A.C.M.D., Dal Molin M., Hanna N., Zafar S.N., Hemmila M., Napolitano L., Wong J.J., Chandler J., Wood L., Wren S., Ottesen T., You L., Yu K., Arcienega Yanez M.D.P., Ferreira Fernandes M., Gonzalez D., Cubas S., Gonzalez M.C., Zubiaurre V., Demolin R., Giroff N., Sciuto P., Campos M., Rodriguez Cantera G., Deepika G., Simuchimba E., Bulaya A., Chibuye C., Chirengendure B., Kabale M.-R., Kabongo K., Munthali J., Mweso O., Pikiti F., Otieno J., Lai L.T., Blackman B., Subramaniam S., Karim R., Kok N., Lee Y.D., Ali S., Sinha A., Corrigan R., Barnes N., Wong F., Dennis G., Jedamzik J., Phillips E., Piette W., Van hentenryck M., Koco H., Lawani S., Kassa M.W., Santos Bezerra T., Gribnev P., Dimitrov D., Krastev P., Oum S., Bonghaseh D.T., Al Farsi M., Alsharqawi N., Acevedo V., Castillo Barbosa A.C., Giron F., Leon Rodriguez J.P., Kucan D., Rosko D., Barsic N., Zupan D., Hegazi A., Truncikova V., Fryba V., Mohamed M., Nagi A., Rashad Temerik A., Elshawy M.E., Mahmoud M.I., Anwar M., Rageh T., Elmokadem A., Gaballa K., Teppo S., Pengerma P., Ballouhey Q., Bergeat D., Weyl A., Hain E., Gyedu A., Yenli E., Osei-Poku D., Rompou V.-A., Zoikas A., Gaitanidis A., Koukis G., Perivoliotis K., Tavlas P., Galanos-Demiris K., Zografos G., Karavokyros I., Xanthopoulou G., Iordanidou E., Ayau F., Garcia A., Damjan P., Wason D., B L A., Rangganata E., Kamath P., O'Connor D.B., Pinto M., Perrone F., Tropeano F.P., Troilo F., Bossi D., Scala D., Pulitano L., Carella M., Pietrabissa A., Gori A., Giraudo G., De Simone V., Russo A.A., Braccio B., Al-Taher R., Athamneh S., Parker A., Sawiee A., Kattia A., Tababa O., Shaeeb Z., Syminas V., Jurgaitis J., Damuleviciene G., Svagzdys S., Razafimanjato N.N.M., Chieng Loo L., Tiong I.C., Wan Muhmad W.F., Vijeyan H., Li Ying T., Grech G., Arrangoiz R., Jimenez Ley V.B., Arizpe D., Lagunes Lara E., Castro Lopez E.V., Eaazim J., Gordinou de Gouberville M., Bastiaenen V., Rottier S., Nahab F., Ji M.Y., Seyoji M., Nwachukwu C., Emeghara O., Muhammed S.E., Idowu A., Sowemimo O., Ogundoyin O., Akande O., Lott A., Nadeem M., Laghari A.A., Loya A., Mushtaq H., Abdullah M.T., Abuhilal B., Atawneh M., Hamdan H., Alhabil B., Srour A., Mousa I., Da Silva Medina L., Bartosiak K., Ferreira P., Francisco V., Lemos R., Frutuoso L., Fernandes S., Fonseca T., Pereira J., Rachadell J., Torre A., Madeira Martins F., Carvalho A.C., Rodrigues Ferreira J., Ribeiro da Silva B., Devesa H., Vieira A., Monica I., Amaro M., Sousa D., Reia M., Louro J., Martins A., Dominguez J., Santos I., Freitas Oliveira N.M., Pereira J.C., Silva-Vaz P., Freire L., Escrevente R., Negoita V.M., Shakhmatov D., Nezerwa Y., Radulovic R., Obery G., Viljoen F., Mendes T., Suarez A., Moncada E., Fernandez-Hevia M., Curtis Martinez C., Gil Garcia J.M., Gonzalez Zunzarren M., Idris T., Eklov K., Grahn O., Amin L., Blomqvist M., Ajani C., Kraus R., Seeger N., Willemin M., Rayya F., Ayash M., Msouti R., Kannas I., Abazid E., Esper A., Slim S., Kavcar A.S., Aytac E., Dural A.C., Ilker A., Eray I.C., Kurnaz E., Altiner S., Tepe M.D., Sahin C., Savli E., Innocent A., Babirye L., Diachenko A., Hordoskiy V., Curry H., Chau C.Y.C., Robertson H., Lennon H., Loi L., Kirkham E., McCann C., Watts D., Gurung B., Wilson M., Tribedi T., Garofalo E., Zahra B., MacDonald S., Daniels I., Ng N., Khosla S., Olivier J., Yue 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V., Ye, G., Zhang, G., Brooker, E., Feng, D., Lau, B., Ngai, C., Birks, S., Gyorki, D., Otero de Pablos, J., Abbosh, A., Gillespie, C., Mahmoud, A., Kwan, B., Lawson, J., Warwick, A., Bingham, J., Cockbain, A. J., Dudi-Venkata, N. N., Ellaby-Hall, J., Finlay, B., Humphries, E., Pisaniello, J., Pisaniello, M., Salih, S., Sammour, T., Abd Wahab, H. H., De Silva, A., Hayward, N., Iyer, K., Maddern, G., Prevost, G. A., Annapureddy, N., Settipalli, K. P., Yeo, J., Hempenstall, L., Pham, L., Purcell, S., Talavera, C., Vaska, A. I., Chaggar, G., Chrapko, P., Cocco, A., Coulter-Nile, S. M. C. J., Ctercteko, G., French, J., Gong, H., Gosselink, M., Jegathees, T., Jin, I., Kalachov, M., Kiefhaber, K., Lee, K., Luong, J., Phan, S., Pleass, H., Veale, K., Zeng, Z., Au, A., Debiasio, A., Deng, I., Myooran, J., Nair, A., Stewart, P., Stift, A., Unger, L. W., Wimmer, K., Ahmed, N., Hasan, S., Rahman, S., O'Shea, M., Padmore, G., Peters, A., Perduca, P., Pulcina, G., Tinton, N., Buxant, F., Dabin, E., Garofalo, G., Dossou, F., Gnangnon, F. H. R., Imorou Souaibou, Y., Motlaleselelo, P., Tlhomelang, O., Lima Buarque, I., Mendonca Ataide Gomes, G., Vieira Barros, A., Batashki, I., Damianov, N., Stoyanov, V., Dardanov, D., Maslyankov, S., Petkov, P., Todorov, G., Zhivkov, E., Akisheva, A., Castilla Moreno, M. A., Genov, G., Ilieva, I., Ivanov, T., Karamanliev, M., Khan, A., Mitkov, E., Yotsov, T., Atanasov, B., Belev, N., Slavchev, M., Nsengiyumva, C., Jones, E., Stock, S., Kyota, S., Brown, J., Mabanza, K. T., Nigo Samuel, L., Otuneme, C., Prosper, N., Umenze, F., Boutros, M., Caminsky, N., Dumitra, S., Garfinkle, R., Morency, D., Salama, E., Banks, A., Ferri, L., He, H., Katz, A., Liberman, A. 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A., Fadel, A., Habater, A., Hamdy, H., Hefni, A., Kamal, M., Mohamed Abobakr, N., Sayed, A., Shaker, N., Taha, E., Tharwat, H., Zakaria, O., Abdelmotaleb, I., Al-Dhufri, A., Al-Himyari, H. S., El sheikh, E., Eldmaty, A., Elkhalawy, A., M. Elkhashen, A., Magdy, K., Mostafa, S., Sadia, H. D., Saleh, M. M., Samir, D., Yahia Mohamed Ali, M., A. Nassar, M., Abdelhady, S., Abdelrazek, A., Abdelsalam, I., El-Sawy, A., Essam, E., Gadelkarim, M., Ghaly, K., Hassabalnaby, M., Masarani, R., Mohamed Shaaban, N., Sabry, A., Salem, M., Soliman, N. A., Zahran, D., Abou, El. soud M. R., Badr, E. T., Borham, H., Elmeslemany, N., Elsayed, M., Elsherif, F., Eslam, S., Gaber, G., Ibrahim, S., Kamh, Y., Mohamed, S. G., Morshedy, E., Omar, C., Salem Soliman, F., Abdelkawy, S., Abdelmohsen, N., Abdelshakour, M., Dahy, A., Gamal, N., Gamal, M., Hasan, A., Hetta, H., Mousa, N., Omar, M., Rabie, S., Saad, M., Saleh, B., Sayed Mohamed, M., Shawqi, M., Abdelhady Mousa, H., Alnoury, M., Elbealawy, M., Elshafey, A., Essam Ibrahim El Desouki Muhammad Ahmed, M., Ghonaim, M., Hgag, F., Ibrahim, M., Morsy, M., Reda Loaloa, M., Refaat, A., Samir, H., Shahien, F., Sobhy, M., Sroor, F., Abdellatif, E., Adel, M., Afifi, A. A., Afifi, E., Antaky, M., Dawoud, A., El Zoghby, N., El-remaily, A., Elzanfaly, A. A., Gadallah, A., Gamal, F. A., Hashem, O., Medhat Youssef, S., Muhammad Attyah, A., Munir, M., Shazly, O., Wilson, K., Adel, S., Ali, A., Eid, E., Elhelow, E., Elmahdy, M., Elshatby, B., Hossam el-din Zakaria, A., Hossny, A., Ibrahim, E., M. 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I., Veiga, D., Azevedo, J., Cardoso Louro, H., Leite, M., Bairos Menezes, M., Gama, B., Brito, D., Cruz Martins, M. C., Graca e Magalhaes, A., Longras, A. C., Lourenco, R., Matos, D., Castro, L., Policarpo, F., Romano, J., Monteiro, C., Pinto, D., Duarte, M., Fortuna Martins, S., Oliveira, M., Galvao, D., Martins, L., Silva, A., Taranu, V., Vieira, B., Neves, J., Oliveira, S., Ribeiro, H., Cinza, M., Felix, R., Machado, A., Oliveira, J., Patricio, J., Pedroso de Lima, R., Pereira, M., Rocha Melo, M., Velez, C., Abreu da Silva, A., Claro, M., Costa Santos, D., Ferreira, A., Capote, H., Rosado, D., Tare, F., Nogueira, O., Angelo, M., Baiao, J. M., Guimaraes, A., Marques, J., Nico Albano, M., Silva, M., Valente da Costa, A., Vieira Caroco, T., Almeida Braga, S., Capunge, I., Fragoso, M., Guimaraes, J., Pinto, B., Ribeiro, J., Angel, M., Fialho, G., Guerrero, M., Campos Costa, F., Cardoso, D., Cardoso, V., Alves, M., Estalagem, I., Louro, T., Marques, C., Martelo, R., Morgado, M., Canotilho, R., Correia, A. M., Martins, P., Peyroteo, M., Gomes, J., Monteiro, R., Romano, M., Alves, D. M., Peixoto, R., Quintela, C., Jervis, M. J., Melo, D., Pacheco, A., Paixao, V., Pedro, V., Pimenta, J., Pimenta de Castro, J., Rocha, A., Beuran, M., Ciubotaru, C., Diaconescu, B., Hostiuc, S., Negoi, I., Stoica, B., Na, N. A., Anokhin, E., Kuznetsov, G., Oganezov, G., Paramzin, F., Romanova, E., Rutkovskii, V., Shushval, M., Zabiyaka, M., Dzhumabaev, K., Ivanov, V., Mamedli, Z., Achkasov, S., Balkarov, A., Nabiev, E., Nagudov, M., Rybakov, E., Saifutdinova, K., Sushkov, O., Joseph, L., Ndayishimiye, I., Faustin, N., Mutabazi, A. 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Subjects
Pediatrics, Colorectal cancer, IMPACT, Disease, Colorectal Neoplasm, 030204 cardiovascular system & hematology, Cancer, surgery, postoperative mortality, 0302 clinical medicine, Postoperative Complications, Global health, 030212 general & internal medicine, Prospective Studies, Prospective cohort study, General Medicine, DISEASES, Income, cancer surgery, Colorectal Neoplasms, Breast Neoplasm, Cohort study, Human, Adult, Developed Countrie, medicine.medical_specialty, Global surgery, General surgery, International multicentre study, Cancer surgery, Breast Neoplasms, Department of Error, NO, Developing Countrie, 03 medical and health sciences, Breast cancer, Stomach Neoplasms, medicine, Humans, Developing Countries, Neoplasm Staging, business.industry, Developed Countries, Odds ratio, CARE, medicine.disease, 3126 Surgery, anesthesiology, intensive care, radiology, Prospective Studie, Postoperative Complication, business
Abstract

80% of individuals with cancer will require a surgical procedure, yet little comparative data exist on early outcomes in low-income and middle-income countries (LMICs). We compared postoperative outcomes in breast, colorectal, and gastric cancer surgery in hospitals worldwide, focusing on the effect of disease stage and complications on postoperative mortality. 80% of individuals with cancer will require a surgical procedure, yet little comparative data exist on early outcomes in low-income and middle-income countries (LMICs). We compared postoperative outcomes in breast, colorectal, and gastric cancer surgery in hospitals worldwide, focusing on the effect of disease stage and complications on postoperative mortality. Background: 80% of individuals with cancer will require a surgical procedure, yet little comparative data exist on early outcomes in low-income and middle-income countries (LMICs). We compared postoperative outcomes in breast, colorectal, and gastric cancer surgery in hospitals worldwide, focusing on the effect of disease stage and complications on postoperative mortality. Methods: This was a multicentre, international prospective cohort study of consecutive adult patients undergoing surgery for primary breast, colorectal, or gastric cancer requiring a skin incision done under general or neuraxial anaesthesia. The primary outcome was death or major complication within 30 days of surgery. Multilevel logistic regression determined relationships within three-level nested models of patients within hospitals and countries. Hospital-level infrastructure effects were explored with three-way mediation analyses. This study was registered with ClinicalTrials.gov, NCT03471494. Findings: Between April 1, 2018, and Jan 31, 2019, we enrolled 15 958 patients from 428 hospitals in 82 countries (high income 9106 patients, 31 countries; upper-middle income 2721 patients, 23 countries; or lower-middle income 4131 patients, 28 countries). Patients in LMICs presented with more advanced disease compared with patients in high-income countries. 30-day mortality was higher for gastric cancer in low-income or lower-middle-income countries (adjusted odds ratio 3·72, 95% CI 1·70–8·16) and for colorectal cancer in low-income or lower-middle-income countries (4·59, 2·39–8·80) and upper-middle-income countries (2·06, 1·11–3·83). No difference in 30-day mortality was seen in breast cancer. The proportion of patients who died after a major complication was greatest in low-income or lower-middle-income countries (6·15, 3·26–11·59) and upper-middle-income countries (3·89, 2·08–7·29). Postoperative death after complications was partly explained by patient factors (60%) and partly by hospital or country (40%). The absence of consistently available postoperative care facilities was associated with seven to 10 more deaths per 100 major complications in LMICs. Cancer stage alone explained little of the early variation in mortality or postoperative complications. Interpretation: Higher levels of mortality after cancer surgery in LMICs was not fully explained by later presentation of disease. The capacity to rescue patients from surgical complications is a tangible opportunity for meaningful intervention. Early death after cancer surgery might be reduced by policies focusing on strengthening perioperative care systems to detect and intervene in common complications. Funding: National Institute for Health Research Global Health Research Unit.

Published
2021

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