1. Quantitative analysis of blood cells and inflammatory factors in wounds
- Author
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S Cerveró-Ferragut, M Soler-Pérez, E Martín-Tomás, N López-Riquelme, J Pomares-Vicente, B Massa-Domínguez, and J F Sánchez-Hernández
- Subjects
Male ,0301 basic medicine ,Exudate ,Pathology ,medicine.medical_specialty ,Nursing (miscellaneous) ,leukocytes ,wound exudate ,inflammatory phase ,Immunoglobulin G ,03 medical and health sciences ,inflammatory markers, inflammatory phase, leukocytes, proliferative phase, wound exudate ,Follicular phase ,medicine ,Humans ,Inflammatory factors ,Platelet ,Inflammation ,Pressure Ulcer ,Wound Healing ,biology ,integumentary system ,business.industry ,Wound.exudate ,030104 developmental biology ,biology.protein ,Cytokines ,Wounds and Injuries ,inflammatory markersphagocyting ,Female ,Fundamentals and skills ,medicine.symptom ,business ,proliferative phase ,Quantitative analysis (chemistry) ,Biomarkers - Abstract
Objective: The aim of this study was to quantify blood cells and inflammatory markers, involved in the healing process, in exudates from wounds in different healing phases, to assess these markers in order to identify the inflammatory phase of the wounds. Method: Patients who presented with postsurgical wounds, which closed by first and second intention, and those who presented with pressure ulcers (PUs), which were closed by second intention, were included in the study. Results: We examined wounds from 37 patients and collected samples from 52 wounds in the inflammatory phase, 30 in the proliferative phase and 29 in the maturation phase. The number of neutrophils and platelets in the exudate collected from wounds in the inflammatory phase was significantly higher (pConclusion: Our findings suggest that the combination of the markers, percentage of neutrophils and monocytes, platelets, CRP and IgG levels could be useful prognostic indicators of the inflammatory phase.
- Published
- 2017