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Mutation in SP7, encoding the osteoblast-specific transcription factor SP7 (also known as osterix), has been described to cause osteogenesis imperfecta (OI) type XII. However, the exact dental phenotype has not been well described. We report the detailed dental manifestation of a boy known to have OI type XII, presented with impacted dentition, necessitating combined oral and maxillofacial surgical and orthodontic treatment. This case also highlighted the need of multidisciplinary team assessment in this group of children.

Zika virus has rapidly spread through the World Health Organization's Region of the Americas since being identified in Brazil in early 2015. Transmitted primarily through the bite of infected Aedes species mosquitoes, Zika virus infection during pregnancy can cause spontaneous abortion and birth defects, including microcephaly (1,2). New York City (NYC) is home to a large number of persons who travel frequently to areas with active Zika virus transmission, including immigrants from these areas. In November 2015, the NYC Department of Health and Mental Hygiene (DOHMH) began developing and implementing plans for managing Zika virus and on February 1, 2016, activated its Incident Command System. During January 1-June 17, 2016, DOHMH coordinated diagnostic laboratory testing for 3,605 persons with travel-associated exposure, 182 (5.0%) of whom had confirmed Zika virus infection. Twenty (11.0%) confirmed patients were pregnant at the time of diagnosis. In addition, two cases of Zika virus-associated Guillain-Barré syndrome were diagnosed. DOHMH's response has focused on 1) identifying and diagnosing suspected cases; 2) educating the public and medical providers about Zika virus risks, transmission, and prevention strategies, particularly in areas with large populations of immigrants from areas with ongoing Zika virus transmission; 3) monitoring pregnant women with Zika virus infection and their fetuses and infants; 4) detecting local mosquito-borne transmission through both human and mosquito surveillance; and 5) modifying existing Culex mosquito control measures by targeting Aedes species of mosquitoes through the use of larvicides and adulticides.

Empirical debate on Initial public offering (IPO) underpricing has never laid to rest. Motivated by the IPO underpricing phenomenon across various market, this paper examines the anomalous market behaviors of IPO in an emerging market setting such as Malaysia. The primary purpose of this paper is to analyze the existence and magnitude of the underpricing phenomenon and post listing performance of IPOs listed in Bursa Malaysia from 2008 to 2016. Moreover, this study aims to provide an insight primarily into the relationship between IPO initial and long-term stock performance and the four main determinants influencing underpricing, namely IPO size, market volatility, underwriter status and the reciprocal of IPO price. By analyzing a sample of 313 IPOs, the average market adjusted initial return is 9.4%. The regression-based analysis indicates positive relationship between underpricing and the explanatory variables, namely IPO size, market volatility, underwriter status and the reciprocal of IPO price. In addition, the findings of the present study lend support to the evidence of a fads hypothesis as the sample IPO was found to underperform the market over a 36-month period after listing and a univariate regression analysis further reveals that there is a negative relationship between initial market adjusted returns and returns over the 36-month period.

The Yang-Mills gradient flow in finite volume is used to define a running coupling scheme. As our main result the discrete β -function, or step scaling function, is calculated for scale change s = 3/2 at several lattice spacings for SU(3) gauge theory coupled to N f = 4 fundamental massless fermions. The continuum extrapolation is performed and agreement is found with the continuum perturbative results for small renormalized coupling. The case of SU(2) gauge group is briefly commented on.

Recent results in computing excited-state energies and meson-meson scattering phase shifts in lattice QCD are presented. A stochastic method of treating the low-lying modes of quark propagation that exploits Laplacian Heaviside quark-field smearing makes such studies possible now on large 32^3 x 256 and 48^3 x 128 lattices at near physical pion masses. Levels are identified using a variety of probe interpolating operators, which include both single-hadron and a large number of two-hadron operators., Talk presented at CIPANP2015, 15 pages, 7 figures. arXiv admin note: substantial text overlap with arXiv:1410.8839, arXiv:1310.7887, arXiv:1410.8843