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112 results on '"Quitadamo, P."'

1. Innovating Bolometers' Mounting: A Gravity-Based Approach

Author: The CUPID Collaboration, Alfonso, K., Armatol, A., Augier, C., Avignone III, F. T., Azzolini, O., Barabash, A. S., Bari, G., Barresi, A., Baudin, D., Bellini, F., Benato, G., Benussi, L., Berest, V., Beretta, M., Bettelli, M., Biassoni, M., Billard, J., Boffelli, F., Boldrini, V., Brandani, E. D., Brofferio, C., Bucci, C., Buchynska, M., Camilleri, J., Campani, A., Cao, J., Capelli, C., Capelli, S., Caracciolo, V., Cardani, L., Carniti, P., Casali, N., Celi, E., Chang, C., Chapellier, M., Chen, H., Chiesa, D., Cintas, D., Clemenza, M., Colantoni, I., Copello, S., Cremonesi, O., Creswick, R. J., D'Addabbo, A., Dafinei, I., Danevich, F. A., De Dominicis, F., De Jesus, M., de Marcillac, P., Dell'Oro, S., Di Domizio, S., Di Lorenzo, S., Dompè, V., Drobizhev, A., Dumoulin, L., Fantini, G., Idrissi, M. El, Faverzani, M., Ferri, E., Ferri, F., Ferroni, F., Figueroa-Feliciano, E., Formaggio, J., Franceschi, A., Fu, S., Fujikawa, B. K., Gascon, J., Ghislandi, S., Giachero, A., Girola, M., Gironi, L., Giuliani, A., Gorla, P., Gotti, C., Grant, C., Gras, P., Guillaumon, P. V., Gutierrez, T. D., Han, K., Hansen, E. V., Heeger, K. M., Helis, D. L., Huang, H. Z., Hurst, M. T., Imbert, L., Juillard, A., Karapetrov, G., Keppel, G., Khalife, H., Kobychev, V. V., Kolomensky, Yu. G., Kowalski, R., Lattaud, H., Lefevre, M., Lisovenko, M., Liu, R., Liu, Y., Loaiza, P., Ma, L., Mancarella, F., Manenti, N., Mariani, A., Marini, L., Marnieros, S., Martinez, M., Maruyama, R. H., Mas, Ph., Mayer, D., Mazzitelli, G., Mazzola, E., Mei, Y., Moore, M. N., Morganti, S., Napolitano, T., Nastasi, M., Nikkel, J., Nones, C., Norman, E. B., Novosad, V., Nutini, I., O'Donnell, T., Olivieri, E., Olmi, M., Oregui, B. T., Pagan, S., Pageot, M., Pagnanini, L., Pasciuto, D., Pattavina, L., Pavan, M., Penek, Ò., Peng, H., Pessina, G., Pettinacci, V., Pira, C., Pirro, S., Pochon, O., Poda, D. V., Polakovic, T., Polischuk, O. G., Pottebaum, E. G., Pozzi, S., Previtali, E., Puiu, A., Puranam, S., Quitadamo, S., Rappoldi, A., Raselli, G. L., Ressa, A., Rizzoli, R., Rosenfeld, C., Rosier, P., Rossella, M., Scarpaci, J. A., Schmidt, B., Serino, R., Shaikina, A., Shang, K., Sharma, V., Shlegel, V. N., Singh, V., Sisti, M., Slocum, P., Speller, D., Surukuchi, P. T., Taffarello, L., Tomassini, S., Tomei, C., Torres, A., Torres, J. A., Tozzi, D., Tretyak, V. I., Trotta, D., Velazquez, M., Vetter, K. J., Wagaarachchi, S. L., Wang, G., Wang, L., Wang, R., Welliver, B., Wilson, J., Wilson, K., Winslow, L. A., Xie, F., Xue, M., Yang, J., Yefremenko, V., Umatov, V. I., Zarytskyy, M. M., Zhu, T., Zolotarova, A., and Zucchelli, S.
Subjects: Physics - Instrumentation and Detectors, High Energy Physics - Experiment, Nuclear Experiment
Abstract: Cryogenic calorimeters, also known as bolometers, are among the leading technologies for searching for rare events. The CUPID experiment is exploiting this technology to deploy a tonne-scale detector to search for neutrinoless double-beta decay of $^{100}$Mo. The CUPID collaboration proposed an innovative approach to assembling bolometers in a stacked configuration, held in position solely by gravity. This gravity-based assembly method is unprecedented in the field of bolometers and offers several advantages, including relaxed mechanical tolerances and simplified construction. To assess and optimize its performance, we constructed a medium-scale prototype hosting 28 Li$_2$MoO$_4$ crystals and 30 Ge light detectors, both operated as cryogenic calorimeters at the Laboratori Nazionali del Gran Sasso (Italy). Despite an unexpected excess of noise in the light detectors, the results of this test proved (i) a thermal stability better than $\pm$0.5 mK at 10 mK, (ii) a good energy resolution of Li$_2$MoO$_4$ bolometers, (6.6 $\pm$ 2.2) keV FWHM at 2615 keV, and (iii) a Li$_2$MoO$_4$ light yield measured by the closest light detector of 0.36 keV/MeV, sufficient to guarantee the particle identification requested by CUPID.
Published: 2025

2. CUPID, the CUORE Upgrade with Particle Identification

Author: The CUPID Collaboration, Alfonso, K., Armatol, A., Augier, C., Avignone III, F. T., Azzolini, O., Barabash, A. S., Bari, G., Barresi, A., Baudin, D., Bellini, F., Benato, G., Benussi, L., Berest, V., Beretta, M., Bettelli, M., Biassoni, M., Billard, J., Boffelli, F., Boldrini, V., Brandani, E. D., Brofferio, C., Bucci, C., Buchynska, M., Camilleri, J., Campani, A., Cao, J., Capelli, C., Capelli, S., Caracciolo, V., Cardani, L., Carniti, P., Casali, N., Celi, E., Chang, C., Chen, H., Chiesa, D., Cintas, D., Clemenza, M., Colantoni, I., Copello, S., Cremonesi, O., Creswick, R. J., D'Addabbo, A., Dafinei, I., Danevich, F. A., De Dominicis, F., De Jesus, M., de Marcillac, P., Dell'Oro, S., Di Domizio, S., Di Lorenzo, S., Dixon, T., Drobizhev, A., Dumoulin, L., Idrissi, M. El, Faverzani, M., Ferri, E., Ferri, F., Ferroni, F., Figueroa-Feliciano, E., Formaggio, J., Franceschi, A., Fu, S., Fujikawa, B. K., Gascon, J., Ghislandi, S., Giachero, A., Girola, M., Gironi, L., Giuliani, A., Gorla, P., Gotti, C., Grant, C., Gras, P., Guillaumon, P. V., Gutierrez, T. D., Han, K., Hansen, E. V., Heeger, K. M., Helis, D. L., Huang, H. Z., Hurst, M. T., Imbert, L., Juillard, A., Karapetrov, G., Keppel, G., Khalife, H., Kobychev, V. V., Kolomensky, Yu. G., Kowalski, R., Lattaud, H., Lefevre, M., Lisovenko, M., Liu, R., Liu, Y., Loaiza, P., Ma, L., Mancarella, F., Manenti, N., Mariani, A., Marini, L., Marnieros, S., Martinez, M., Maruyama, R. H., Mas, Ph., Mayer, D., Mazzitelli, G., Mazzola, E., Mei, Y., Moore, M. N., Morganti, S., Napolitano, T., Nastasi, M., Nikkel, J., Nones, C., Norman, E. B., Novosad, V., Nutini, I., O'Donnell, T., Olivieri, E., Olmi, M., Oregui, B. T., Pagan, S., Pageot, M., Pagnanini, L., Pasciuto, D., Pattavina, L., Pavan, M., Penek, Ö., Peng, H., Pessina, G., Pettinacci, V., Pira, C., Pirro, S., Pochon, O., Poda, D. V., Polakovic, T., Polischuk, O. G., Pottebaum, E. G., Pozzi, S., Previtali, E., Puiu, A., Puranam, S., Quitadamo, S., Rappoldi, A., Raselli, G. L., Ressa, A., Rizzoli, R., Rosenfeld, C., Rosier, P., Rossella, M., Scarpaci, J. A., Schmidt, B., Serino, R., Shaikina, A., Shang, K., Sharma, V., Shlegel, V. N., Singh, V., Sisti, M., Slocum, P., Speller, D., Surukuchi, P. T., Taffarello, L., Tomassini, S., Tomei, C., Torres, A., Torres, J. A., Tozzi, D., Tretyak, V. I., Trotta, D., Velazquez, M., Vetter, K. J., Wagaarachchi, S. L., Wang, G., Wang, L., Wang, R., Welliver, B., Wilson, J., Wilson, K., Winslow, L. A., Xie, F., Xue, M., Yang, J., Yefremenko, V., Umatov, V. I., Zarytskyy, M. M., Zhu, T., Zolotarova, A., and Zucchelli, S.
Subjects: Physics - Instrumentation and Detectors, High Energy Physics - Experiment, Nuclear Experiment
Abstract: CUPID, the CUORE Upgrade with Particle Identification, is a next-generation experiment to search for neutrinoless double beta decay ($0\nu\beta\beta$) and other rare events using enriched Li$_2$$^{100}$MoO$_4$ scintillating bolometers. It will be hosted by the CUORE cryostat located at the Laboratori Nazionali del Gran Sasso in Italy. The main physics goal of CUPID is to search for $0\nu\beta\beta$\ of $^{100}$Mo with a discovery sensitivity covering the full neutrino mass regime in the inverted ordering scenario, as well as the portion of the normal ordering regime with lightest neutrino mass larger than 10 meV. With a conservative background index of 10$^{-4}$ cnts/(keV$\cdot$kg$\cdot$yr), 240 kg isotope mass, 5 keV FWHM energy resolution and 10 live-years of data taking, CUPID will have a 90\% C.L. half-life exclusion sensitivity of 1.8 $\cdot$ 10$^{27}$ yr, corresponding to an effective Majorana neutrino mass ($m_{\beta\beta}$) sensitivity of 9--15 meV, and a $3\sigma$ discovery sensitivity of 1 $\cdot$ 10$^{27}$ yr, corresponding to an $m_{\beta\beta}$ range of 12--21 meV., Comment: Prepared for submission to EPJC; 24 pages, 6 figures, and 2 tables
Published: 2025

3. Potential of RES-NOVA as Dark Matter observatory

Author: Alloni, D., Benato, G., Carniti, P., Cataldo, M., Chen, L., Clemenza, M., Consonni, M., Croci, G., Dafinei, I., Danevich, F. A., Di Martino, D., Di Stefano, E., Iachellini, N. Ferreiro, Ferroni, F., Filippini, F., Ghislandi, S., Giachero, A., Gironi, L., Gorla, P., Gotti, C., Helis, D. L., Kasperovych, D. V., Kobychev, V. V., Marcucci, G., Melchiorre, A., Menegolli, A., Nisi, S., Musa, M., Pagnanini, L., Pattavina, L., Pessina, G., Pirro, S., Polischuk, O. G., Pozzi, S., Prata, M. C., Puiu, A., Quitadamo, S., Riccardi, M. P., Rossella, M., Rossini, R., Saliu, F., Salvini, A., Scherban, A. P., Solopikhin, D. A., Tretyak, V. I., Trotta, D., and Yuan, H.
Subjects: Physics - Instrumentation and Detectors, Astrophysics - Cosmology and Nongalactic Astrophysics
Abstract: The RES-NOVA project is an experimental initiative aimed at detecting neutrinos from the next galactic supernova using PbWO$_{4}$ cryogenic detectors, operated at low temperatures in a low-background environment. By utilizing archaeological lead (Pb) as the target material, RES-NOVA leverages its high radiopurity, large nuclear mass, and the natural abundance of $^{207}$Pb, making it well-suited for exploring both spin-independent and spin-dependent Dark Matter (DM) interactions via nuclear scattering. This work presents a background model developed for the RES-NOVA technology demonstrator and evaluates its implications for Dark Matter detection. Detailed calculations of nuclear matrix elements, combined with the unique properties of archaeological Pb, demonstrate RES-NOVA's potential as a complementary tool to existing direct detection experiments for studying Dark Matter interactions. The experiment will conduct DM searches over a broad mass range spanning 4 orders of magnitude, from sub-GeV/$c^2$ to TeV/$c^2$. In the most optimistic scenario, RES-NOVA is expected to probe DM-nucleon cross-sections down to 1$\times 10^{-43}$ cm$^2$ and 2$\times 10^{-46}$ cm$^2$ for candidates with masses of 2 GeV/$c^2$ and 20 GeV/$c^2$, respectively., Comment: updated limit calculation
Published: 2025

4. Search for Fractionally Charged Particles with CUORE

Author: Adams, DQ, Alduino, C, Alfonso, K, Avignone, FT, Azzolini, O, Bari, G, Bellini, F, Benato, G, Beretta, M, Biassoni, M, Branca, A, Brofferio, C, Bucci, C, Camilleri, J, Caminata, A, Campani, A, Cao, J, Capelli, S, Capelli, C, Cappelli, L, Cardani, L, Carniti, P, Casali, N, Celi, E, Chiesa, D, Clemenza, M, Copello, S, Cremonesi, O, Creswick, RJ, D’Addabbo, A, Dafinei, I, Del Corso, F, Dell’Oro, S, Di Domizio, S, Di Lorenzo, S, Dixon, T, Dompè, V, Fang, DQ, Fantini, G, Faverzani, M, Ferri, E, Ferroni, F, Fiorini, E, Franceschi, MA, Freedman, SJ, Fu, SH, Fujikawa, BK, Ghislandi, S, Giachero, A, Girola, M, Gironi, L, Giuliani, A, Gorla, P, Gotti, C, Guillaumon, PV, Gutierrez, TD, Han, K, Hansen, EV, Heeger, KM, Helis, DL, Huang, HZ, Keppel, G, Kolomensky, Yu G, Kowalski, R, Liu, R, Ma, L, G., Y, Marini, L, Maruyama, RH, Mayer, D, Mei, Y, Moore, MN, Napolitano, T, Nastasi, M, Nones, C, Norman, EB, Nucciotti, A, Nutini, I, O’Donnell, T, Olmi, M, Oregui, BT, Ouellet, JL, Pagan, S, Pagliarone, CE, Pagnanini, L, Pallavicini, M, Pattavina, L, Pavan, M, Pessina, G, Pettinacci, V, Pira, C, Pirro, S, Pottebaum, EG, Pozzi, S, Previtali, E, Puiu, A, Quitadamo, S, Ressa, A, Rosenfeld, C, and Schmidt, B
Subjects: Nuclear and Plasma Physics, Particle and High Energy Physics, Physical Sciences, CUORE Collaboration, Mathematical Sciences, Engineering, General Physics, Mathematical sciences, Physical sciences
Abstract: The Cryogenic Underground Observatory for Rare Events (CUORE) is a detector array comprised by 988 5 cm×5 cm×5 cm TeO_{2} crystals held below 20 mK, primarily searching for neutrinoless double-beta decay in ^{130}Te. Unprecedented in size among cryogenic calorimetric experiments, CUORE provides a promising setting for the study of exotic throughgoing particles. Using the first tonne year of CUORE's exposure, we perform a search for hypothesized fractionally charged particles (FCPs), which are well-motivated by various standard model extensions and would have suppressed interactions with matter. Across the searched range of charges e/24-e/2 no excess of FCP candidate tracks is observed over background, setting leading limits on the underground FCP flux with charges e/24-e/5 at 90% confidence level. Using the low background environment and segmented geometry of CUORE, we establish the sensitivity of tonne-scale subkelvin detectors to diverse signatures of new physics.
Published: 2024

5. Search for fractionally charged particles with CUORE

Author: CUORE Collaboration, Adams, D. Q., Alduino, C., Alfonso, K., Avignone III, F. T., Azzolini, O., Bari, G., Bellini, F., Benato, G., Beretta, M., Biassoni, M., Branca, A., Brofferio, C., Bucci, C., Camilleri, J., Caminata, A., Campani, A., Cao, J., Capelli, S., Capelli, C., Cappelli, L., Cardani, L., Carniti, P., Casali, N., Celi, E., Chiesa, D., Clemenza, M., Copello, S., Cremonesi, O., Creswick, R. J., D'Addabbo, A., Dafinei, I., Del Corso, F., Dell'Oro, S., Di Domizio, S., Di Lorenzo, S., Dixon, T., Dompè, V., Fang, D. Q., Fantini, G., Faverzani, M., Ferri, E., Ferroni, F., Fiorini, E., Franceschi, M. A., Freedman, S. J., Fu, S. H., Fujikawa, B. K., Ghislandi, S., Giachero, A., Girola, M., Gironi, L., Giuliani, A., Gorla, P., Gotti, C., Guillaumon, P. V., Gutierrez, T. D., Han, K., Hansen, E. V., Heeger, K. M., Helis, D. L., Huang, H. Z., Keppel, G., Kolomensky, Yu. G., Kowalski, R., Liu, R., Ma, L., Ma, Y. G., Marini, L., Maruyama, R. H., Mayer, D., Mei, Y., Moore, M. N., Napolitano, T., Nastasi, M., Nones, C., Norman, E. B., Nucciotti, A., Nutini, I., O'Donnell, T., Olmi, M., Oregui, B. T., Ouellet, J. L., Pagan, S., Pagliarone, C. E., Pagnanini, L., Pallavicini, M., Pattavina, L., Pavan, M., Pessina, G., Pettinacci, V., Pira, C., Pirro, S., Pottebaum, E. G., Pozzi, S., Previtali, E., Puiu, A., Quitadamo, S., Ressa, A., Rosenfeld, C., Schmidt, B., Sharma, V., Singh, V., Sisti, M., Speller, D., Stark, P., Surukuchi, P. T., Taffarello, L., Tomei, C., Torres, A., Torres, J. A., Vetter, K. J., Vignati, M., Wagaarachchi, S. L., Welliver, B., Wilson, J., Wilson, K., Winslow, L. A., Zimmermann, S., and Zucchelli, S.
Subjects: High Energy Physics - Experiment, Physics - Instrumentation and Detectors
Abstract: The Cryogenic Underground Observatory for Rare Events (CUORE) is a detector array comprised by 988 5$\;$cm$\times$5$\;$cm$\times$5$\;$cm TeO$_2$ crystals held below 20 mK, primarily searching for neutrinoless double-beta decay in $^{130}$Te. Unprecedented in size amongst cryogenic calorimetric experiments, CUORE provides a promising setting for the study of exotic through-going particles. Using the first tonne-year of CUORE's exposure, we perform a search for hypothesized fractionally charged particles (FCPs), which are well-motivated by various Standard Model extensions and would have suppressed interactions with matter. No excess of FCP candidate tracks is observed over background, setting leading limits on the underground FCP flux with charges between $e/24-e/5$ at 90\% confidence level. Using the low background environment and segmented geometry of CUORE, we establish the sensitivity of tonne-scale sub-Kelvin detectors to diverse signatures of new physics., Comment: 7 pages, 5 figures
Published: 2024

6. Data-driven background model for the CUORE experiment

Author: CUORE Collaboration, Adams, D. Q., Alduino, C., Alfonso, K., Avignone III, F. T., Azzolini, O., Bari, G., Bellini, F., Benato, G., Beretta, M., Biassoni, M., Branca, A., Brofferio, C., Bucci, C., Camilleri, J., Caminata, A., Campani, A., Cao, J., Capelli, S., Capelli, C., Cappelli, L., Cardani, L., Carniti, P., Casali, N., Celi, E., Chiesa, D., Clemenza, M., Cremonesi, O., Creswick, R. J., D'Addabbo, A., Dafinei, I., Del Corso, F., Dell'Oro, S., Di Domizio, S., Di Lorenzo, S., Dixon, T., Dompè, V., Fang, D. Q., Fantini, G., Faverzani, M., Ferri, E., Ferroni, F., Fiorini, E., Franceschi, M. A., Freedman, S. J., Fu, S. H., Fujikawa, B. K., Ghislandi, S., Giachero, A., Girola, M., Gironi, L., Giuliani, A., Gorla, P., Gotti, C., Guillaumon, P. V., Gutierrez, T. D., Han, K., Hansen, E. V., Heeger, K. M., Helis, D. L., Huang, H. Z., Keppel, G., Kolomensky, Yu. G., Kowalski, R., Liu, R., Ma, L., Ma, Y. G., Marini, L., Maruyama, R. H., Mayer, D., Mei, Y., Moore, M. N., Napolitano, T., Nastasi, M., Nones, C., Norman, E. B., Nucciotti, A., Nutini, I., O'Donnell, T., Olmi, M., Oregui, B. T., Ouellet, J. L., Pagan, S., Pagliarone, C. E., Pagnanini, L., Pallavicini, M., Pattavina, L., Pavan, M., Pessina, G., Pettinacci, V., Pira, C., Pirro, S., Ponce, I., Pottebaum, E. G., Pozzi, S., Previtali, E., Puiu, A., Quitadamo, S., Ressa, A., Rosenfeld, C., Schmidt, B., Sharma, V., Singh, V., Sisti, M., Speller, D., Surukuchi, P. T., Taffarello, L., Tomei, C., Torres, J. A, Vetter, K. J., Vignati, M., Wagaarachchi, S. L., Welliver, B., Wilson, J., Wilson, K., Winslow, L. A., Zimmermann, S., and Zucchelli, S.
Subjects: Nuclear Experiment, Astrophysics - Instrumentation and Methods for Astrophysics, Physics - Instrumentation and Detectors
Abstract: We present the model we developed to reconstruct the CUORE radioactive background based on the analysis of an experimental exposure of 1038.4 kg yr. The data reconstruction relies on a simultaneous Bayesian fit applied to energy spectra over a broad energy range. The high granularity of the CUORE detector, together with the large exposure and extended stable operations, allow for an in-depth exploration of both spatial and time dependence of backgrounds. We achieve high sensitivity to both bulk and surface activities of the materials of the setup, detecting levels as low as 10 nBq kg$^{-1}$ and 0.1 nBq cm$^{-2}$, respectively. We compare the contamination levels we extract from the background model with prior radio-assay data, which informs future background risk mitigation strategies. The results of this background model play a crucial role in constructing the background budget for the CUPID experiment as it will exploit the same CUORE infrastructure.
Published: 2024
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7. The environmental low-frequency background for macro-calorimeters at the millikelvin scale

Author: Aragão, L., Armigliato, A., Brancaccio, R., Brofferio, C., Castellaro, S., D'Addabbo, A., De Luca, G., Del Corso, F., Di Sabatino, S., Liu, R., Marini, L., Nutini, I., Quitadamo, S., Ruggieri, P., Vetter, K. J., Zavatarelli, M., and Zucchelli, S.
Subjects: Physics - Instrumentation and Detectors, Nuclear Experiment, Physics - Atmospheric and Oceanic Physics
Abstract: Many of the most sensitive physics experiments searching for rare events, like neutrinoless double beta ($0\nu\beta\beta$) decay and dark matter interactions, rely on cryogenic macro-calorimeters operating at the mK-scale. Located underground at the Gran Sasso National Laboratory (LNGS), in central Italy, CUORE (Cryogenic Underground Observatory for Rare Events) is one of the leading experiments for the search of $0\nu\beta\beta$ decay, implementing the low-temperature calorimetric technology. We present a novel multi-detector analysis to correlate environmental phenomena with the low-frequency noise of low-temperature calorimeters. Indeed, the correlation of marine and seismic data with data from a pair of CUORE detectors indicates that cryogenic detectors are sensitive not only to intense vibrations generated by earthquakes, but also to the much fainter vibrations induced by marine microseisms in the Mediterranean Sea due to the motion of sea waves. Proving that cryogenic macro-calorimeters are sensitive to such environmental sources of noise opens the possibility of studying their impact on the detectors physics-case sensitivity. Moreover, this study could pave the road for technology developments dedicated to the mitigation of the noise induced by marine microseisms, from which the entire community of cryogenic calorimeters can benefit.
Published: 2024
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8. With or without $\nu$? Hunting for the seed of the matter-antimatter asymmetry

Author: CUORE Collaboration, Adams, D. Q., Alduino, C., Alfonso, K., Avignone III, F. T., Azzolini, O., Bari, G., Bellini, F., Benato, G., Beretta, M., Biassoni, M., Branca, A., Brofferio, C., Bucci, C., Camilleri, J., Caminata, A., Campani, A., Cao, J., Capelli, S., Capelli, C., Cappelli, L., Cardani, L., Carniti, P., Casali, N., Celi, E., Chiesa, D., Clemenza, M., Cremonesi, O., Creswick, R. J., D'Addabbo, A., Dafinei, I., Del Corso, F., Dell'Oro, S., Di Domizio, S., Di Lorenzo, S., Dixon, T., Dompè, V., Fang, D. Q., Fantini, G., Faverzani, M., Ferri, E., Ferroni, F., Fiorini, E., Franceschi, M. A., Freedman, S. J., Fu, S. H., Fujikawa, B. K., Ghislandi, S., Giachero, A., Girola, M., Gironi, L., Giuliani, A., Gorla, P., Gotti, C., Guillaumon, P. V., Gutierrez, T. D., Han, K., Hansen, E. V., Heeger, K. M., Helis, D. L., Huang, H. Z., Keppel, G., Kolomensky, Yu. G., Kowalski, R., Liu, R., Ma, L., Ma, Y. G., Marini, L., Maruyama, R. H., Mayer, D., Mei, Y., Moore, M. N., Napolitano, T., Nastasi, M., Nones, C., Norman, E. B., Nucciotti, A., Nutini, I., O'Donnell, T., Olmi, M., Oregui, B. T., Ouellet, J. L., Pagan, S., Pagliarone, C. E., Pagnanini, L., Pallavicini, M., Pattavina, L., Pavan, M., Pessina, G., Pettinacci, V., Pira, C., Pirro, S., Ponce, I., Pottebaum, E. G., Pozzi, S., Previtali, E., Puiu, A., Quitadamo, S., Ressa, A., Rosenfeld, C., Schmidt, B., Sharma, V., Singh, V., Sisti, M., Speller, D., Surukuchi, P. T., Taffarello, L., Tomei, C., Torres, J. A, Vetter, K. J., Vignati, M., Wagaarachchi, S. L., Welliver, B., Wilson, J., Wilson, K., Winslow, L. A., Zimmermann, S., and Zucchelli, S.
Subjects: Nuclear Experiment
Abstract: The matter-antimatter asymmetry underlines the incompleteness of the current understanding of particle physics. Neutrinoless double-beta ($0\nu \beta\beta$) decay may help explain this asymmetry, while unveiling the Majorana nature of the neutrino. The CUORE experiment searches for $0\nu \beta\beta$ decay of $^{130}$Te using a tonne-scale cryogenic calorimeter operated at milli-kelvin temperatures. We report no evidence for $0\nu \beta\beta$ decay and place a lower limit on the half-life of T$_{1/2}$ $>$ 3.8 $\times$ 10$^{25}$ years (90% C.I.) with over 2 tonne$\cdot$year TeO$_2$ exposure. The tools and techniques developed for this result and the 5 year stable operation of nearly 1000 detectors demonstrate the infrastructure for a next-generation experiment capable of searching for $0\nu \beta\beta$ decay across multiple isotopes.
Published: 2024

9. Data-driven background model for the CUORE experiment

Author: Adams, DQ, Alduino, C, Alfonso, K, Avignone, FT, Azzolini, O, Bari, G, Bellini, F, Benato, G, Beretta, M, Biassoni, M, Branca, A, Brofferio, C, Bucci, C, Camilleri, J, Caminata, A, Campani, A, Cao, J, Capelli, S, Capelli, C, Cappelli, L, Cardani, L, Carniti, P, Casali, N, Celi, E, Chiesa, D, Clemenza, M, Cremonesi, O, Creswick, RJ, D’Addabbo, A, Dafinei, I, Del Corso, F, Dell’Oro, S, Di Domizio, S, Di Lorenzo, S, Dixon, T, Dompè, V, Fang, DQ, Fantini, G, Faverzani, M, Ferri, E, Ferroni, F, Fiorini, E, Franceschi, MA, Freedman, SJ, Fu, SH, Fujikawa, BK, Ghislandi, S, Giachero, A, Girola, M, Gironi, L, Giuliani, A, Gorla, P, Gotti, C, Guillaumon, PV, Gutierrez, TD, Han, K, Hansen, EV, Heeger, KM, Helis, DL, Huang, HZ, Keppel, G, Kolomensky, Yu G, Kowalski, R, Liu, R, Ma, L, G., Y, Marini, L, Maruyama, RH, Mayer, D, Mei, Y, Moore, MN, Napolitano, T, Nastasi, M, Nones, C, Norman, EB, Nucciotti, A, Nutini, I, O’Donnell, T, Olmi, M, Oregui, BT, Ouellet, JL, Pagan, S, Pagliarone, CE, Pagnanini, L, Pallavicini, M, Pattavina, L, Pavan, M, Pessina, G, Pettinacci, V, Pira, C, Pirro, S, Ponce, I, Pottebaum, EG, Pozzi, S, Previtali, E, Puiu, A, Quitadamo, S, Ressa, A, Rosenfeld, C, and Schmidt, B
Subjects: Nuclear and Plasma Physics, Physical Sciences, Cancer, NSD-Neutrinos
Abstract: We present the model we developed to reconstruct the CUORE radioactive background based on the analysis of an experimental exposure of 1038.4 kg yr. The data reconstruction relies on a simultaneous Bayesian fit applied to energy spectra over a broad energy range. The high granularity of the CUORE detector, together with the large exposure and extended stable operations, allow for an in-depth exploration of both spatial and time dependence of backgrounds. We achieve high sensitivity to both bulk and surface activities of the materials of the setup, detecting levels as low as 10 nBq kg-1 and 0.1 nBq cm-2, respectively. We compare the contamination levels we extract from the background model with prior radio-assay data, which informs future background risk mitigation strategies. The results of this background model play a crucial role in constructing the background budget for the CUPID experiment as it will exploit the same CUORE infrastructure.
Published: 2024

10. Simultaneous Measurement of Half-Life and Spectral Shape of $^{115}$In $\beta$-decay with an Indium Iodide Cryogenic Calorimeter

Author: Pagnanini, L., Benato, G., Carniti, P., Celi, E., Chiesa, D., Corbett, J., Dafinei, I., Di Domizio, S., Di Stefano, P., Ghislandi, S., Gotti, C., Helis, D. L., Knobel, R., Kostensalo, J., Kotila, J., Nagorny, S., Pessina, G., Pirro, S., Pozzi, S., Puiu, A., Quitadamo, S., Sisti, M., Suhonen, J., and Kuznetsov, S.
Subjects: Nuclear Experiment, Nuclear Theory
Abstract: Current bounds on neutrino Majorana mass are affected by significant uncertainties in the nuclear calculations for neutrinoless double-beta decay. A key issue for a data-driven improvement of the nuclear theory is the actual value of the axial coupling constant $g_A$, which can be investigated through forbidden $\beta$-decays. We present the first measurement of 4$^{th}$-forbidden $\beta$-decay of $^{115}$In with a cryogenic calorimeter based on Indium Iodide. Exploiting the enhanced spectral shape method for the first time to this isotope, our study accurately determines simultaneously spectral shape, $g_A$, and half-life. The Interacting Shell Model, which best fits our data, indicates a half-life for this decay at $T_{1/2}=(5.26\pm0.06) \times 10^{14}$,yr.
Published: 2024
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11. Array of Cryogenic Calorimeters to Evaluate the Spectral Shape of forbidden $\beta$-decays: the ACCESS project

Author: Pagnanini, L., Benato, G., Carniti, P., Celi, E., Chiesa, D., Corbett, J., Dafinei, I., Di Domizio, S., Di Stefano, P., Ghislandi, S., Gotti, C., Helis, D. L., Knobel, R., Kostensalo, J., Kotila, J., Nagorny, S., Pessina, G., Pirro, S., Pozzi, S., Puiu, A., Quitadamo, S., Sisti, M., Suhonen, J., and Kuznetsov, S.
Subjects: Physics - Instrumentation and Detectors, Nuclear Experiment
Abstract: The ACCESS (Array of Cryogenic Calorimeters to Evaluate Spectral Shapes) project aims to establish a novel technique to perform precision measurements of forbidden \b{eta}-decays, which can serve as an important benchmark for nuclear physics calculations and represent a significant background in astroparticle physics experiments. ACCESS will operate a pilot array of cryogenic calorimeters based on natural and doped crystals containing \b{eta}-emitting radionuclides. In this way, natural (e.g. 113 Cd and 115In) and synthetic isotopes (e.g. 99Tc) will be simultaneously measured with a common experimental technique. The array will also include further crystals optimised to disentangle the different background sources, thus reducing the systematic uncertainty. In this paper, we give an overview of the ACCESS research program, discussing a detector design study and promising results of 115In., Comment: 12 pages, 12 figures
Published: 2023
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12. A first test of CUPID prototypal light detectors with NTD-Ge sensors in a pulse-tube cryostat

Author: CUPID collaboration, Alfonso, K., Armatol, A., Augier, C., Avignone III, F. T., Azzolini, O., Balata, M., Barabash, A. S., Bari, G., Barresi, A., Baudin, D., Bellini, F., Benato, G., Berest, V., Beretta, M., Bettelli, M., Biassoni, M., Billard, J., Boldrini, V., Branca, A., Brofferio, C., Bucci, C., Camilleri, J., Campani, A., Capelli, C., Capelli, S., Cappelli, L., Cardani, L., Carniti, P., Casali, N., Celi, E., Chang, C., Chiesa, D., Clemenza, M., Colantoni, I., Copello, S., Craft, E., Cremonesi, O., Creswick, R. J., Cruciani, A., D'Addabbo, A., D'Imperio, G., Dabagov, S., Dafinei, I., Danevich, F. A., De Jesus, M., de Marcillac, P., Dell'Oro, S., Di Domizio, S., Di Lorenzo, S., Dixon, T., Dompé, V., Drobizhev, A., Dumoulin, L., Fantini, G., Faverzani, M., Ferri, E., Ferri, F., Ferroni, F., Figueroa-Feliciano, E., Foggetta, L., Formaggio, J., Franceschi, A., Fu, C., Fu, S., Fujikawa, B. K., Gallas, A., Gascon, J., Ghislandi, S., Giachero, A., Gianvecchio, A., Girola, M., Gironi, L., Giuliani, A., Gorla, P., Gotti, C., Grant, C., Gras, P., Guillaumon, P. V., Gutierrez, T. D., Han, K., Hansen, E. V., Heeger, K. M., Helis, D. L., Huang, H. Z., Imbert, L., Johnston, J., Juillard, A., Karapetrov, G., Keppel, G., Khalife, H., Kobychev, V. V., Kolomensky, Yu. G., Konovalov, S. I., Kowalski, R., Langford, T., Lefevre, M., Liu, R., Liu, Y., Loaiza, P., Ma, L., Madhukuttan, M., Mancarella, F., Marini, L., Marnieros, S., Martinez, M., Maruyama, R. H., Mas, Ph., Mayer, D., Mazzitelli, G., Mei, Y., Milana, S., Morganti, S., Napolitano, T., Nastasi, M., Nikkel, J., Nisi, S., Nones, C., Norman, E. B., Novosad, V., Nutini, I., O'Donnell, T., Olivieri, E., Olmi, M., Ouellet, J. L., Pagan, S., Pagliarone, C., Pagnanini, L., Pattavina, L., Pavan, M., Peng, H., Pessina, G., Pettinacci, V., Pira, C., Pirro, S., Poda, D. V., Polischuk, O. G., Ponce, I., Pozzi, S., Previtali, E., Puiu, A., Quitadamo, S., Ressa, A., Rizzoli, R., Rosenfeld, C., Rosier, P., Scarpaci, J. A., Schmidt, B., Sharma, V., Shlegel, V. N., Singh, V., Sisti, M., Slocum, P., Speller, D., Surukuchi, P. T., Taffarello, L., Tomei, C., Torres, J. A., Tretyak, V. I., Tsymbaliuk, A., Velazquez, M., Vetter, K. J., Wagaarachchi, S. L., Wang, G., Wang, L., Wang, R., Welliver, B., Wilson, J., Wilson, K., Winslow, L. A., Xue, M., Yan, L., Yang, J., Yefremenko, V., Umatov, V. I., Zarytskyy, M. M., Zhang, J., Zolotarova, A., and Zucchelli, S.
Subjects: Physics - Instrumentation and Detectors, Nuclear Experiment
Abstract: CUPID is a next-generation bolometric experiment aiming at searching for neutrinoless double-beta decay with ~250 kg of isotopic mass of $^{100}$Mo. It will operate at $\sim$10 mK in a cryostat currently hosting a similar-scale bolometric array for the CUORE experiment at the Gran Sasso National Laboratory (Italy). CUPID will be based on large-volume scintillating bolometers consisting of $^{100}$Mo-enriched Li$_2$MoO$_4$ crystals, facing thin Ge-wafer-based bolometric light detectors. In the CUPID design, the detector structure is novel and needs to be validated. In particular, the CUORE cryostat presents a high level of mechanical vibrations due to the use of pulse tubes and the effect of vibrations on the detector performance must be investigated. In this paper we report the first test of the CUPID-design bolometric light detectors with NTD-Ge sensors in a dilution refrigerator equipped with a pulse tube in an above-ground lab. Light detectors are characterized in terms of sensitivity, energy resolution, pulse time constants, and noise power spectrum. Despite the challenging noisy environment due to pulse-tube-induced vibrations, we demonstrate that all the four tested light detectors comply with the CUPID goal in terms of intrinsic energy resolution of 100 eV RMS baseline noise. Indeed, we have measured 70--90 eV RMS for the four devices, which show an excellent reproducibility. We have also obtained outstanding energy resolutions at the 356 keV line from a $^{133}$Ba source with one light detector achieving 0.71(5) keV FWHM, which is -- to our knowledge -- the best ever obtained when compared to $\gamma$ detectors of any technology in this energy range., Comment: Prepared for submission to JINST; 16 pages, 7 figures, and 1 table
Published: 2023
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13. Twelve-crystal prototype of Li$_2$MoO$_4$ scintillating bolometers for CUPID and CROSS experiments

Author: CUPID, collaborations, CROSS, Alfonso, K., Armatol, A., Augier, C., Avignone III, F. T., Azzolini, O., Balata, M., Bandac, I. C., Barabash, A. S., Bari, G., Barresi, A., Baudin, D., Bellini, F., Benato, G., Berest, V., Beretta, M., Bettelli, M., Biassoni, M., Billard, J., Boldrini, V., Branca, A., Brofferio, C., Bucci, C., Calvo-Mozota, J. M., Camilleri, J., Campani, A., Capelli, C., Capelli, S., Cappelli, L., Cardani, L., Carniti, P., Casali, N., Celi, E., Chang, C., Chiesa, D., Clemenza, M., Colantoni, I., Copello, S., Craft, E., Cremonesi, O., Creswick, R. J., Cruciani, A., D'Addabbo, A., D'Imperio, G., Dabagov, S., Dafinei, I., Danevich, F. A., De Jesus, M., de Marcillac, P., Dell'Oro, S., Di Domizio, S., Di Lorenzo, S., Dixon, T., Dompé, V., Drobizhev, A., Dumoulin, L., Fantini, G., Faverzani, M., Ferri, E., Ferri, F., Ferroni, F., Figueroa-Feliciano, E., Foggetta, L., Formaggio, J., Franceschi, A., Fu, C., Fu, S., Fujikawa, B. K., Gallas, A., Gascon, J., Ghislandi, S., Giachero, A., Gianvecchio, A., Girola, M., Gironi, L., Giuliani, A., Gorla, P., Gotti, C., Grant, C., Gras, P., Guillaumon, P. V., Gutierrez, T. D., Han, K., Hansen, E. V., Heeger, K. M., Helis, D. L., Huang, H. Z., Ianni, A., Imbert, L., Johnston, J., Juillard, A., Karapetrov, G., Keppel, G., Khalife, H., Kobychev, V. V., Kolomensky, Yu. G., Konovalov, S. I., Kowalski, R., Langford, T., Lefevre, M., Liu, R., Liu, Y., Loaiza, P., Ma, L., Madhukuttan, M., Mancarella, F., Marrache-Kikuchi, C. A., Marini, L., Marnieros, S., Martinez, M., Maruyama, R. H., Mas, Ph., Mayer, D., Mazzitelli, G., Mei, Y., Milana, S., Morganti, S., Napolitano, T., Nastasi, M., Nikkel, J., Nisi, S., Nones, C., Norman, E. B., Novosad, V., Nutini, I., O'Donnell, T., Olivieri, E., Olmi, M., Ouellet, J. L., Pagan, S., Pagliarone, C., Pagnanini, L., Pattavina, L., Pavan, M., Peng, H., Pessina, G., Pettinacci, V., Pira, C., Pirro, S., Poda, D. V., Polischuk, O. G., Ponce, I., Pozzi, S., Previtali, E., Puiu, A., Quitadamo, S., Ressa, A., Rizzoli, R., Rosenfeld, C., Rosier, P., Scarpaci, J. A., Schmidt, B., Sharma, V., Shlegel, V. N., Singh, V., Sisti, M., Slocum, P., Speller, D., Surukuchi, P. T., Taffarello, L., Tomei, C., Torres, J. A., Tretyak, V. I., Tsymbaliuk, A., Velazquez, M., Vetter, K. J., Wagaarachchi, S. L., Wang, G., Wang, L., Wang, R., Welliver, B., Wilson, J., Wilson, K., Winslow, L. A., Xue, M., Yan, L., Yang, J., Yefremenko, V., Umatov, V. I., Zarytskyy, M. M., Zhang, J., Zolotarova, A., and Zucchelli, S.
Subjects: Physics - Instrumentation and Detectors, Nuclear Experiment
Abstract: An array of twelve 0.28 kg lithium molybdate (LMO) low-temperature bolometers equipped with 16 bolometric Ge light detectors, aiming at optimization of detector structure for CROSS and CUPID double-beta decay experiments, was constructed and tested in a low-background pulse-tube-based cryostat at the Canfranc underground laboratory in Spain. Performance of the scintillating bolometers was studied depending on the size of phonon NTD-Ge sensors glued to both LMO and Ge absorbers, shape of the Ge light detectors (circular vs. square, from two suppliers), in different light collection conditions (with and without reflector, with aluminum coated LMO crystal surface). The scintillating bolometer array was operated over 8 months in the low-background conditions that allowed to probe a very low, $\mu$Bq/kg, level of the LMO crystals radioactive contamination by $^{228}$Th and $^{226}$Ra., Comment: Prepared for submission to JINST; 23 pages, 9 figures, and 4 tables
Published: 2023
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14. Development of ultralow-background cryogenic calorimeters for the measurement of surface α contamination

Author: Benato, G, Biassoni, M, Brofferio, C, Celi, E, Dell'Oro, S, Drobizhev, A, Gianvecchio, A, Girola, M, Ghislandi, S, Kolomensky, Yu G, Nutini, I, Olmi, M, Pagnanini, L, Puiu, A, and Quitadamo, S
Subjects: Biomedical and Clinical Sciences, Clinical Sciences, Oncology and Carcinogenesis, Bolometric α detector, Low-radioactivity measurements, Material screening, Atomic, Molecular, Nuclear, Particle and Plasma Physics, Other Physical Sciences, Nuclear Medicine & Medical Imaging, Clinical sciences, Oncology and carcinogenesis
Abstract: Next-generation experiments searching for rare events must satisfy increasingly stringent requirements on the bulk and surface radioactive contamination of their active and structural materials. The measurement of surface contamination is particularly challenging, as no existing technology is capable of separately measuring parts of the 232Th and 238U decay chains that are commonly found to be out of secular equilibrium. We will present the results obtained with a detector prototype consisting of 8 silicon wafers of 150 mm diameter instrumented as bolometers and operated in a low-background dilution refrigerator at the Gran Sasso Underground Laboratory of INFN, Italy. The prototype was characterized by a baseline energy resolution of few keV and a background
Published: 2023

15. Status and prospects of discovery of 0??? decay with the CUORE detector

Author: Adams, DQ, Alduino, C, Alfonso, K, Avignone, FTIII, Azzolini, O, Bari, G, Bellini, F, Benato, G, Beretta, M, Biassoni, M, Branca, A, Brofferio, C, Bucci, C, Camilleri, J, Caminata, A, Campani, A, Canonica, L, Cao, XG, Capelli, S, Capelli, C, Cappelli, L, Cardani, L, Carniti, P, Casali, N, Celi, E, Chiesa, D, Clemenza, M, Copello, S, Cremonesi, O, Creswick, RJ, D'Addabbo, A, Dafinei, I, Del Corso, F, Dell'Oro, S, Di Domizio, S, Di Lorenzo, S, Dompe, V, Fang, DQ, Fantini, G, Faverzani, M, Ferri, E, Ferroni, F, Fiorini, E, Franceschi, MA, Freedman, SJ, Fu, SH, Fujikawa, BK, Ghislandi, S, Giachero, A, Gianvecchio, A, Gironi, L, Giuliani, A, Gorla, P, Gotti, C, Gutierrez, TD, Han, K, Hansen, EV, Heeger, KM, Huang, RG, Huang, HZ, Johnston, J, Keppel, G, Kolomensky, Yu G, Kowalski, R, Ligi, C, Liu, R, Ma, L, Ma, YG, Marini, L, Maruyama, RH, Mayer, D, Mei, Y, Morganti, S, Napolitano, T, Nastasi, M, Nikkel, J, Nones, C, Norman, EB, Nucciotti, A, Nutini, I, O'Donnell, T, Olmi, M, Ouellet, JL, Pagan, S, Pagliarone, CE, Pagnanini, L, Pallavicini, M, Pattavina, L, Pavan, M, Pessina, G, Pettinacci, V, Pira, C, Pirro, S, Ponce, I, Pozzi, S, Previtali, E, Puiu, A, Quitadamo, S, Ressa, A, and Rosenfeld, C
Subjects: Astronomy & Astrophysics, Geophysics, Particle and high energy physics
Abstract: In this contribution we present the achievements of the CUORE experiment so far. It is the first tonne-scale bolometric detector and it is in stable data taking since 2018. We reached to collect about 1800 kg×yr of exposure of which more than 1 ton×year have been analysed. The CUORE detector is meant to search for the neutrinoless double β decay (0νββ) of the 130Te isotope. This is a beyond Standard Model process which could establish the nature of the neutrino to be Dirac or a Majorana particle. It is an alternative mode of the two-neutrinos double β decay, a rare decay which have been precisely measured by CUORE in the 130Te. We found no evidence of the 0νββ and we set a Bayesian lower limit of 2.2 ×1025yr on its half-life. The expertise achieved by CUORE set a milestone for any future bolometric detector, including CUPID, which is the planned next generation experiment searching for 0νββ with scintillating bolometers.
Published: 2023

16. Characterization of a kg-scale archaeological lead-based cryogenic detectors for the RES-NOVA experiment

Author: Beeman, J. W., Benato, G., Bucci, C., Canonica, L., Carniti, P., Celi, E., Clemenza, M., D'Addabbo, A., Danevich, F. A., Di Domizio, S., Di Lorenzo, S., Dubovik, O. M., Iachellini, N. Ferreiro, Ferroni, F., Fiorini, E., Fu, S., Garai, A., Ghislandi, S., Gironi, L., Gorla, P., Gotti, C., Guillaumon, P. V., Helis, D. L., Kovtun, G. P., Mancuso, M., Marini, L., Olmi, M., Pagnanini, L., Pattavina, L., Pessina, G., Petricca, F., Pirro, S., Pozzi, S., Puiu, A., Quitadamo, S., Rothe, J., Scherban, A. P., Schönert, S., Solopikhin, D. A., Strauss, R., Tarabini, E., Tretyak, V. I., Tupitsyna, I. A., and Wagner, V.
Subjects: Physics - Instrumentation and Detectors
Abstract: One of the most energetic events in the Universe are core-collapse Supernovae (SNe), where almost all the star's binding energy is released as neutrinos. These particles are direct probes of the processes occurring in the stellar core and provide unique insights into the gravitational collapse. RES-NOVA will revolutionize how we detect neutrinos from astrophysical sources, by deploying the first ton-scale array of cryogenic detectors made from archaeological lead. Pb offers the highest neutrino interaction cross-section via coherent elastic neutrino-nucleus scattering (CE$\nu$NS). Such process will enable RES-NOVA to be equally sensitive to all neutrino flavors. For the first time, we propose to use archaeological Pb as sensitive target material in order to achieve an ultra-low background level in the region of interest (\textit{O}(1keV)). All these features make possible the deployment of the first cm-scale neutrino telescope for the investigation of astrophysical sources. In this contribution, we will characterize the radiopurity level and the performance of a small-scale proof-of-principle detector of RES-NOVA, consisting in a PbWO$_4$ crystal made from archaeological-Pb operated as cryogenic detector.
Published: 2022

17. An Energy-dependent Electro-thermal Response Model of CUORE Cryogenic Calorimeter

Author: CUORE Collaboration, Adams, D. Q., Alduino, C., Alfonso, K., Avignone III, F. T., Azzolini, O., Bari, G., Bellini, F., Benato, G., Beretta, M., Biassoni, M., Branca, A., Brofferio, C., Bucci, C., Camilleri, J., Caminata, A., Campani, A., Canonica, L., Cao, X. G., Capelli, S., Capelli, C., Cappelli, L., Cardani, L., Carniti, P., Casali, N., Celi, E., Chiesa, D., Clemenza, M., Copello, S., Cremonesi, O., Creswick, R. J., D'Addabbo, A., Dafinei, I., Del Corso, F., Dell'Oro, S., Di Domizio, S., Di Lorenzo, S., Dompè, V., Fang, D. Q., Fantini, G., Faverzani, M., Ferri, E., Ferroni, F., Fiorini, E., Franceschi, M. A., Freedman, S. J., Fu, S. H., Fujikawa, B. K., Ghislandi, S., Giachero, A., Gianvecchio, A., Gironi, L., Giuliani, A., Gorla, P., Gotti, C., Gutierrez, T. D., Han, K., Hansen, E. V., Heeger, K. M., Huang, R. G., Huang, H. Z., Johnston, J., Keppel, G., Kolomensky, Yu. G., Kowalski, R., Li, M., Liu, R., Ma, L., Ma, Y. G., Marini, L., Maruyama, R. H., Mayer, D., Mei, Y., Morganti, S., Napolitano, T., Nastasi, M., Nikkel, J., Nones, C., Norman, E. B., Nucciotti, A., Nutini, I., O'Donnell, T., Olmi, M., Ouellet, J. L., Pagan, S., Pagliarone, C. E., Pagnanini, L., Pallavicini, M., Pattavina, L., Pavan, M., Pessina, G., Pettinacci, V., Pira, C., Pirro, S., Pozzi, S., Previtali, E., Puiu, A., Quitadamo, S., Ressa, A., Rosenfeld, C., Sangiorgio, S., Schmidt, B., Scielzo, N. D., Sharma, V., Singh, V., Sisti, M., Speller, D., Surukuchi, P. T., Taffarello, L., Terranova, F., Tomei, C., Vetter, K. J., Vignati, M., Wagaarachchi, S. L., Wang, B. S., Welliver, B., Wilson, J., Wilson, K., Winslow, L. A., Zimmermann, S., and Zucchelli, S.
Subjects: Physics - Instrumentation and Detectors, Nuclear Experiment
Abstract: The Cryogenic Underground Observatory for Rare Events (CUORE) is the most sensitive experiment searching for neutrinoless double-beta decay ($0\nu\beta\beta$) in $^{130}\text{Te}$. CUORE uses a cryogenic array of 988 TeO$_2$ calorimeters operated at $\sim$10 mK with a total mass of 741 kg. To further increase the sensitivity, the detector response must be well understood. Here, we present a non-linear thermal model for the CUORE experiment on a detector-by-detector basis. We have examined both equilibrium and dynamic electro-thermal models of detectors by numerically fitting non-linear differential equations to the detector data of a subset of CUORE channels which are well characterized and representative of all channels. We demonstrate that the hot-electron effect and electric-field dependence of resistance in NTD-Ge thermistors alone are inadequate to describe our detectors' energy dependent pulse shapes. We introduce an empirical second-order correction factor in the exponential temperature dependence of the thermistor, which produces excellent agreement with energy-dependent pulse shape data up to 6 MeV. We also present a noise analysis using the fitted thermal parameters and show that the intrinsic thermal noise is negligible compared to the observed noise for our detectors., Comment: 34 pages, 14 figures, 6 tables
Published: 2022

18. New direct limit on neutrinoless double beta decay half-life of $^{128}$Te with CUORE

Author: Adams, D. Q., Alduino, C., Alfonso, K., Avignone III, F. T., Azzolini, O., Bari, G., Bellini, F., Benato, G., Beretta, M., Biassoni, M., Branca, A., Brofferio, C., Bucci, C., Camilleri, J., Caminata, A., Campani, A., Canonica, L., Cao, X. G., Capelli, C., Capelli, S., Cappelli, L., Cardani, L., Carniti, P., Casali, N., Celi, E., Chiesa, D., Clemenza, M., Copello, S., Cremonesi, O., Creswick, R. J., D'Addabbo, A., Dafinei, I., Del Corso, F., Dell'Oro, S., Di Domizio, S., Di Lorenzo, S., Dompè, V., Fang, D. Q., Fantini, G., Faverzani, M., Ferri, E., Ferroni, F., Fiorini, E., Franceschi, M. A., Freedman, S. J., Fu, S. H., Fujikawa, B. K., Ghislandi, S., Giachero, A., Gianvecchio, A., Gironi, L., Giuliani, A., Gorla, P., Gotti, C., Gutierrez, T. D., Han, K., Hansen, E. V., Heeger, K. M., Huang, R. G., Huang, H. Z., Johnston, J., Keppel, G., Kolomensky, Yu. G., Kowalski, R., Ligi, C., Liu, R., Ma, L., Ma, Y. G., Marini, L., Maruyama, R. H., Mayer, D., Mei, Y., Morganti, S., Napolitano, T., Nastasi, M., Nikkel, J., Nones, C., Norman, E. B., Nucciotti, A., Nutini, I., O'Donnell, T., Olmi, M., Ouellet, J. L., Pagan, S., Pagliarone, C. E., Pagnanini, L., Pallavicini, M., Pattavina, L., Pavan, M., Pessina, G., Pettinacci, V., Pira, C., Pirro, S., Pozzi, S., Previtali, E., Puiu, A., Quitadamo, S., Ressa, A., Rosenfeld, C., Sangiorgio, S., Schmidt, B., Scielzo, N. D., Sharma, V., Singh, V., Sisti, M., Speller, D., Surukuchi, P. T., Taffarello, L., Terranova, F., Tomei, C., Vetter, K. J., Vignati, M., Wagaarachchi, S. L., Wang, B. S., Welliver, B., Wilson, J., Wilson, K., Winslow, L. A., Zimmermann, S., and Zucchelli, S.
Subjects: Nuclear Experiment
Abstract: The Cryogenic Underground Observatory for Rare Events (CUORE) at Laboratori Nazionali del Gran Sasso of INFN in Italy is an experiment searching for neutrinoless double beta (0$\nu\beta\beta$) decay. Its main goal is to investigate this decay in $^{130}$Te, but its ton-scale mass and low background make CUORE sensitive to other rare processes as well. In this work, we present our first results on the search for \nbb decay of $^{128}$Te, the Te isotope with the second highest natural isotopic abundance. We find no evidence for this decay, and using a Bayesian analysis we set a lower limit on the $^{128}$Te \nbb decay half-life of T$_{1/2} > 3.6 \times 10^{24}$ yr (90\% CI). This represents the most stringent limit on the half-life of this isotope, improving by over a factor 30 the previous direct search results, and exceeding those from geochemical experiments for the first time.
Published: 2022
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19. Latest Results from the CUORE Experiment

Author: Nutini, I, Adams, DQ, Alduino, C, Alfonso, K, Avignone, FT, Azzolini, O, Bari, G, Bellini, F, Benato, G, Beretta, M, Biassoni, M, Branca, A, Brofferio, C, Bucci, C, Camilleri, J, Caminata, A, Campani, A, Canonica, L, Cao, XG, Capelli, S, Cappelli, L, Cardani, L, Carniti, P, Casali, N, Celi, E, Chiesa, D, Clemenza, M, Copello, S, Cremonesi, O, Creswick, RJ, D’Addabbo, A, Dafinei, I, Dell’Oro, S, Domizio, SD, Dompè, V, Fang, DQ, Fantini, G, Faverzani, M, Ferri, E, Ferroni, F, Fiorini, E, Franceschi, MA, Freedman, SJ, Fu, SH, Fujikawa, BK, Ghislandi, S, Giachero, A, Gironi, L, Giuliani, A, Gorla, P, Gotti, C, Gutierrez, TD, Han, K, Hansen, EV, Heeger, KM, Huang, RG, Huang, HZ, Johnston, J, Keppel, G, Kolomensky, YG, Kowalski, R, Ligi, C, Liu, R, Ma, L, Ma, YG, Marini, L, Maruyama, RH, Mayer, D, Mei, Y, Moggi, N, Morganti, S, Napolitano, T, Nastasi, M, Nikkel, J, Nones, C, Norman, EB, Nucciotti, A, O’Donnell, T, Ouellet, JL, Pagan, S, Pagliarone, CE, Pagnanini, L, Pallavicini, M, Pattavina, L, Pavan, M, Pessina, G, Pettinacci, V, Pira, C, Pirro, S, Pozzi, S, Previtali, E, Puiu, A, Quitadamo, S, Rosenfeld, C, Rusconi, C, Sakai, M, Sangiorgio, S, Schmidt, B, Scielzo, ND, and Sharma, V
Subjects: Mathematical Physics, Classical Physics, Condensed Matter Physics, General Physics, Classical physics, Condensed matter physics
Abstract: The Cryogenic Underground Observatory for Rare Events (CUORE) is the first cryogenic experiment searching for 0 νββ decay that has been able to reach the one-tonne mass scale. The detector, located at the Laboratori Nazionali del Gran Sasso (LNGS) in Italy, consists of an array of 988 TeO 2 crystals arranged in a compact cylindrical structure of 19 towers. CUORE began its first physics data run in 2017 at a base temperature of about 10 mK and in April 2021 released its 3 rd result of the search for 0 νββ, corresponding to a tonne-year of TeO 2 exposure. This is the largest amount of data ever acquired with a solid state detector and the most sensitive measurement of 0 νββ decay in 130Te ever conducted. We present the current status of CUORE search for 0 νββ with the updated statistics of one tonne-yr. We finally give an update of the CUORE background model and the measurement of the 130Te 2 νββ decay half-life and decay to excited states of 130Xe , studies performed using an exposure of 300.7 kg yr.
Published: 2022

20. Expected sensitivity to 128Te neutrinoless double beta decay with the CUORE TeO2 cryogenic bolometers

Author: Dompè, V, Adams, DQ, Alduino, C, Alfonso, K, Avignone, FT, Azzolini, O, Bari, G, Bellini, F, Benato, G, Beretta, M, Biassoni, M, Branca, A, Brofferio, C, Bucci, C, Camilleri, J, Caminata, A, Campani, A, Canonica, L, Cao, XG, Capelli, S, Cappelli, L, Cardani, L, Carniti, P, Casali, N, Celi, E, Chiesa, D, Clemenza, M, Copello, S, Cremonesi, O, Creswick, RJ, D’Addabbo, A, Dafinei, I, Dell’Oro, S, Di Domizio, S, Di Lorenzo, S, Fang, DQ, Fantini, G, Faverzani, M, Ferri, E, Ferroni, F, Fiorini, E, Franceschi, MA, Freedman, SJ, Fu, SH, Fujikawa, BK, Ghislandi, S, Giachero, A, Gironi, L, Giuliani, A, Gorla, P, Gotti, C, Gutierrez, TD, Han, K, Hansen, EV, Heeger, KM, Huang, RG, Huang, HZ, Johnston, J, Keppel, G, Kolomensky, Yu G, Kowalski, R, Ligi, C, Liu, R, Ma, L, Ma, YG, Marini, L, Maruyama, RH, Mayer, D, Mei, Y, Moggi, N, Morganti, S, Napolitano, T, Nastasi, M, Nikkel, J, Nones, C, Norman, EB, Nucciotti, A, Nutini, I, O’Donnell, T, Olmi, M, Ouellet, JL, Pagan, S, Pagliarone, CE, Pagnanini, L, Pallavicini, M, Pattavina, L, Pavan, M, Pessina, G, Pettinacci, V, Pira, C, Pirro, S, Pozzi, S, Previtali, E, Puiu, A, Quitadamo, S, Ressa, A, Rosenfeld, C, Rusconi, C, Sakai, M, and Sangiorgio, S
Subjects: Nuclear and Plasma Physics, Particle and High Energy Physics, Physical Sciences, Neutrinoless double beta decay, Tellurium, 128-Te, Cryogenic bolometers, Mathematical Physics, Classical Physics, Condensed Matter Physics, General Physics, Classical physics, Condensed matter physics
Abstract: The CUORE experiment is a ton-scale array of TeO 2 cryogenic bolometers located at the underground Laboratori Nazionali del Gran Sasso of Istituto Nazionale di Fisica Nucleare (INFN), in Italy. The CUORE detector consists of 988 crystals operated as source and detector at a base temperature of ∼ 10 mK. Such cryogenic temperature is reached and maintained by means of a custom built cryogen-free dilution cryostat, designed with the aim of minimizing the vibrational noise and the environmental radioactivity. The primary goal of CUORE is the search for neutrinoless double beta decay of 130Te , but thanks to its large target mass and ultra-low background it is suitable for the study of other rare processes as well, such as the neutrinoless double beta decay of 128Te. This tellurium isotope is an attractive candidate for the search of this process, due to its high natural isotopic abundance of 31.75%. The transition energy at (866.7 ± 0.7) keV lies in a highly populated region of the energy spectrum, dominated by the contribution of the two-neutrino double beta decay of 130Te. As the first ton-scale infrastructure operating cryogenic TeO 2 bolometers in stable conditions, CUORE is able to achieve a factor > 10 higher sensitivity to the neutrinoless double beta decay of this isotope with respect to past direct experiments.
Published: 2022

21. New Direct Limit on Neutrinoless Double Beta Decay Half-Life of Te128 with CUORE

Author: Adams, DQ, Alduino, C, Alfonso, K, Avignone, FT, Azzolini, O, Bari, G, Bellini, F, Benato, G, Beretta, M, Biassoni, M, Branca, A, Brofferio, C, Bucci, C, Camilleri, J, Caminata, A, Campani, A, Canonica, L, Cao, XG, Capelli, S, Capelli, C, Cappelli, L, Cardani, L, Carniti, P, Casali, N, Celi, E, Chiesa, D, Clemenza, M, Copello, S, Cremonesi, O, Creswick, RJ, D’Addabbo, A, Dafinei, I, Del Corso, F, Dell’Oro, S, Di Domizio, S, Di Lorenzo, S, Dompè, V, Fang, DQ, Fantini, G, Faverzani, M, Ferri, E, Ferroni, F, Fiorini, E, Franceschi, MA, Freedman, SJ, Fu, SH, Fujikawa, BK, Ghislandi, S, Giachero, A, Gianvecchio, A, Gironi, L, Giuliani, A, Gorla, P, Gotti, C, Gutierrez, TD, Han, K, Hansen, EV, Heeger, KM, Huang, RG, Huang, HZ, Johnston, J, Keppel, G, Kolomensky, Yu G, Kowalski, R, Liu, R, Ma, L, G., Y, Marini, L, Maruyama, RH, Mayer, D, Mei, Y, Morganti, S, Napolitano, T, Nastasi, M, Nikkel, J, Nones, C, Norman, EB, Nucciotti, A, Nutini, I, O’Donnell, T, Olmi, M, Ouellet, JL, Pagan, S, Pagliarone, CE, Pagnanini, L, Pallavicini, M, Pattavina, L, Pavan, M, Pessina, G, Pettinacci, V, Pira, C, Pirro, S, Pozzi, S, Previtali, E, Puiu, A, Quitadamo, S, Ressa, A, Rosenfeld, C, Sangiorgio, S, and Schmidt, B
Subjects: Nuclear and Plasma Physics, Particle and High Energy Physics, Physical Sciences, Half-Life, Bayes Theorem, Granisetron, CUORE Collaboration, Mathematical Sciences, Engineering, General Physics, Mathematical sciences, Physical sciences
Abstract: The Cryogenic Underground Observatory for Rare Events (CUORE) at Laboratori Nazionali del Gran Sasso of INFN in Italy is an experiment searching for neutrinoless double beta (0νββ) decay. Its main goal is to investigate this decay in ^{130}Te, but its ton-scale mass and low background make CUORE sensitive to other rare processes as well. In this Letter, we present our first results on the search for 0νββ decay of ^{128}Te, the Te isotope with the second highest natural isotopic abundance. We find no evidence for this decay, and using a Bayesian analysis we set a lower limit on the ^{128}Te 0νββ decay half-life of T_{1/2}>3.6×10^{24} yr (90% CI). This represents the most stringent limit on the half-life of this isotope, improving by over a factor of 30 the previous direct search results, and exceeding those from geochemical experiments for the first time.
Published: 2022

22. An energy-dependent electro-thermal response model of CUORE cryogenic calorimeter

Author: Adams, DQ, Alduino, C, Alfonso, K, Avignone, FT, Azzolini, O, Bari, G, Bellini, F, Benato, G, Beretta, M, Biassoni, M, Branca, A, Brofferio, C, Bucci, C, Camilleri, J, Caminata, A, Campani, A, Canonica, L, Cao, XG, Capelli, S, Capelli, C, Cappelli, L, Cardani, L, Carniti, P, Casali, N, Celi, E, Chiesa, D, Clemenza, M, Copello, S, Cremonesi, O, Creswick, RJ, D'Addabbo, A, Dafinei, I, Del Corso, F, Dell'Oro, S, Di Domizio, S, Di Lorenzo, S, Dompè, V, Fang, DQ, Fantini, G, Faverzani, M, Ferri, E, Ferroni, F, Fiorini, E, Franceschi, MA, Freedman, SJ, Fu, SH, Fujikawa, BK, Ghislandi, S, Giachero, A, Gianvecchio, A, Gironi, L, Giuliani, A, Gorla, P, Gotti, C, Gutierrez, TD, Han, K, Hansen, EV, Heeger, KM, Huang, RG, Huang, HZ, Johnston, J, Keppel, G, Kolomensky, Yu G, Kowalski, R, Li, M, Liu, R, Ma, L, Ma, YG, Marini, L, Maruyama, RH, Mayer, D, Mei, Y, Morganti, S, Napolitano, T, Nastasi, M, Nikkel, J, Nones, C, Norman, EB, Nucciotti, A, Nutini, I, O'Donnell, T, Olmi, M, Ouellet, JL, Pagan, S, Pagliarone, CE, Pagnanini, L, Pallavicini, M, Pattavina, L, Pavan, M, Pessina, G, Pettinacci, V, Pira, C, Pirro, S, Pozzi, S, Previtali, E, Puiu, A, Quitadamo, S, Ressa, A, Rosenfeld, C, and Sangiorgio, S
Subjects: Nuclear and Plasma Physics, Synchrotrons and Accelerators, Physical Sciences, Cryogenic detectors, Detector modelling and simulations I (interaction of radiation with matter, interaction of photons with matter, interaction of hadrons with matter etc), Double-beta decay detectors, Engineering, Nuclear & Particles Physics, Physical sciences
Abstract: The Cryogenic Underground Observatory for Rare Events (CUORE) is the most sensitive experiment searching for neutrinoless double-beta decay (0νββ) in 130Te. CUORE uses a cryogenic array of 988 TeO2 calorimeters operated at ∼10 mK with a total mass of 741 kg. To further increase the sensitivity, the detector response must be well understood. Here, we present a non-linear thermal model for the CUORE experiment on a detector-by-detector basis. We have examined both equilibrium and dynamic electro-thermal models of detectors by numerically fitting non-linear differential equations to the detector data of a subset of CUORE channels which are well characterized and representative of all channels. We demonstrate that the hot-electron effect and electric-field dependence of resistance in NTD-Ge thermistors alone are inadequate to describe our detectors' energy-dependent pulse shapes. We introduce an empirical second-order correction factor in the exponential temperature dependence of the thermistor, which produces excellent agreement with energy-dependent pulse shape data up to 6 MeV. We also present a noise analysis using the fitted thermal parameters and show that the intrinsic thermal noise is negligible compared to the observed noise for our detectors.
Published: 2022

23. Search for Neutrinoless $\beta^+EC$ Decay of $^{120}$Te with CUORE

Author: Adams, D. Q., Alduino, C., Alfonso, K., Avignone III, F. T., Azzolini, O., Bari, G., Bellini, F., Benato, G., Beretta, M., Biassoni, M., Branca, A., Brofferio, C., Bucci, C., Camilleri, J., Caminata, A., Campani, A., Canonica, L., Cao, X. G., Capelli, C., Capelli, S., Cappelli, L., Cardani, L., Carniti, P., Casali, N., Celi, E., Chiesa, D., Clemenza, M., Copello, S., Cremonesi, O., Creswick, R. J., D'Addabbo, A., Dafinei, I., Del Corso, F., Dell'Oro, S., Di Domizio, S., Di Lorenzo, S., Dompè, V., Fang, D. Q., Fantini, G., Faverzani, M., Ferri, E., Ferroni, F., Fiorini, E., Franceschi, M. A., Freedman, S. J., Fu, S. H., Fujikawa, B. K., Ghislandi, S., Giachero, A., Gianvecchio, A., Gironi, L., Giuliani, A., Gorla, P., Gotti, C., Gutierrez, T. D., Han, K., Hansen, E. V., Heeger, K. M., Huang, R. G., Huang, H. Z., Johnston, J., Keppel, G., Kolomensky, Yu. G., Kowalski, R., Ligi, C., Liu, R., Ma, L., Ma, Y. G., Marini, L., Maruyama, R. H., Mayer, D., Mei, Y., Morganti, S., Napolitano, T., Nastasi, M., Nikkel, J., Nones, C., Norman, E. B., Nucciotti, A., Nutini, I., O'Donnell, T., Olmi, M., Ouellet, J. L., Pagan, S., Pagliarone, C. E., Pagnanini, L., Pallavicini, M., Pattavina, L., Pavan, M., Pessina, G., Pettinacci, V., Pira, C., Pirro, S., Pozzi, S., Previtali, E., Puiu, A., Quitadamo, S., Ressa, A., Rosenfeld, C., Sakai, M., Sangiorgio, S., Schmidt, B., Scielzo, N. D., Sharma, V., Singh, V., Sisti, M., Speller, D., Surukuchi, P. T., Taffarello, L., Terranova, F., Tomei, C., Vetter, K. J., Vignati, M., Wagaarachchi, S. L., Wang, B. S., Welliver, B., Wilson, J., Wilson, K., Winslow, L. A., Zimmermann, S., and Zucchelli, S.
Subjects: Nuclear Experiment
Abstract: CUORE is a large scale cryogenic experiment searching for neutrinoless double beta decay ($0\nu\beta\beta$) in $^{130}$Te. The CUORE detector is made of natural tellurium, providing the possibility of rare event searches on isotopes other than $^{130}$Te. In this work we describe a search for neutrinoless positron emitting electron capture ($0\nu\beta^+EC$) decay in $^{120}$Te with a total TeO$_2$ exposure of 355.7 kg $\cdot$ yr, corresponding to 0.2405 kg $\cdot$ yr of $^{120}$Te. Albeit $0 \nu \beta\beta$ with two final state electrons represents the most promising channel, the emission of a positron and two 511-keV $\gamma$s make $0\nu\beta^+EC$ decay signature extremely clear. To fully exploit the potential offered by the detector modularity we include events with different topology and perform a simultaneous fit of five selected signal signatures. Using blinded data we extract a median exclusion sensitivity of $3.4 \cdot 10^{22}$ yr at 90% Credibility Interval (C.I.). After unblinding we find no evidence of $0\nu\beta^+EC$ signal and set a 90% C.I. Bayesian lower limit of $2.9 \cdot 10^{22}$ yr on $^{120}$Te half-life. This result improves by an order of magnitude the existing limit from the combined analysis of CUORE-0 and Cuoricino.
Published: 2022
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24. Toward CUPID-1T

Author: Armatol, A., Augier, C., Avignone III, F. T., Azzolini, O., Balata, M., Ballen, K., Barabash, A. S., Bari, G., Barresi, A., Baudin, D., Bellini, F., Benato, G., Beretta, M., Bettelli, M., Biassoni, M., Billard, J., Boldrini, V., Branca, A., Brofferio, C., Bucci, C., Camilleri, J., Capelli, C., Capelli, S., Cappelli, L., Cardani, L., Carniti, P., Casali, N., Celi, E., Chang, C., Chiesa, D., Clemenza, M., Colantoni, I., Copello, S., Craft, E., Cremonesi, O., Creswick, R. J., Cruciani, A., D'Addabbo, A., D'Imperio, G., Dabagov, S., Dafinei, I., De Jesus, M., de Marcillac, P., Dell'Oro, S., Di Domizio, S., Di Lorenzo, S., Dixon, T., Dompè, V., Drobizhev, A., Dumoulin, L., Fantini, G., Faverzani, M., Ferri, E., Ferri, F., Ferroni, F., Figueroa-Feliciano, E., Foggetta, L., Formaggio, J., Franceschi, A., Fu, C., Fu, S., Fujikawa, B. K., Gallas, A., Gascon, J., Ghislandi, S., Giachero, A., Gianvecchio, A., Gironi, L., Giuliani, A., Gorla, P., Gotti, C., Grant, C., Gras, P., Guillaumon, P. V., Gutierrez, T. D., Han, K., Hansen, E. V., Heeger, K. M., Helis, D., Helis, D. L., Huang, H. Z., Huang, R. G., Imbert, L., Johnston, J., Juillard, A., Karapetrov, G., Keppel, G., Khalife, H., Kobychev, V. V., Kolomensky, Yu. G., Konovalov, S. I., Kowalski, R., Langford, T., Liu, R., Liu, Y., Loaiza, P., Ma, L., Madhukuttan, M., Mancarella, F., Marini, L., Marnieros, S., Martinez, M., Maruyama, R. H., Mauri, B., Mayer, D., Mazzitelli, G., Mei, Y., Milana, S., Morganti, S., Napolitano, T., Nastasi, M., Nikkel, J., Nisi, S., Nones, C., Norman, E. B., Novosad, V., Nutini, I., O'Donnell, T., Olivieri, E., Olmi, M., Ouellet, J. L., Pagan, S., Pagliarone, C., Pagnanini, L., Pattavina, L., Pavan, M., Peng, H., Pessina, G., Pettinacci, V., Pira, C., Pirro, S., Poda, D. V., Polischuk, O. G., Ponce, I., Pozzi, S., Previtali, E., Puiu, A., Quitadamo, S., Ressa, A., Rizzoli, R., Rosenfeld, C., Rosier, P., Scarpaci, J., Schmidt, B., Sharma, V., Shlegel, V., Singh, V., Sisti, M., Slocum, P., Speller, D., Surukuchi, P. T., Taffarello, L., Tomei, C., Torres, J., Tretyak, V. I., Tsymbaliuk, A., Velazquez, M., Vetter, K. J., Wagaarachchi, S. L., Wang, G., Wang, L., Wang, R., Welliver, B., Wilson, J., Wilson, K., Winslow, L. A., Xue, M., Yan, L., Yang, J., Yefremenko, V., Umatov, V. I., Zarytskyy, M. M., Zhang, J., Zolotarova, A., and Zucchelli, S.
Subjects: Nuclear Experiment
Abstract: Current experiments to search for broken lepton-number symmetry through the observation of neutrinoless double-beta decay ($0\mathrm{\nu\beta\beta}$) provide the most stringent limits on the Majorana nature of neutrinos and the effective Majorana neutrino mass ($m_{\beta\beta}$). The next-generation experiments will focus on the sensitivity to the $0\mathrm{\nu\beta\beta}$ half-life of $\mathcal{O}(10^{27}$--$10^{28}$~years$)$ and $m_{\beta\beta}\lesssim15$~meV, which would provide complete coverage of the so-called Inverted Ordering region of the neutrino mass parameter space. By taking advantage of recent technological breakthroughs, new, future calorimetric experiments at the 1-ton scale can increase the sensitivity by at least another order of magnitude, exploring the large fraction of the parameter space that corresponds to the Normal neutrino mass ordering. In case of a discovery, such experiments could provide important insights toward a new understanding of the mechanism of $0\mathrm{\nu\beta\beta}$. We present here a series of projects underway that will provide advancements in background reduction, cryogenic readout, and physics searches beyond $0\mathrm{\nu\beta\beta}$, all moving toward the next-to-next generation CUPID-1T detector., Comment: contribution to Snowmass 2021
Published: 2022

25. Radiopurity of a kg-scale PbWO$_4$ cryogenic detector produced from archaeological Pb for the RES-NOVA experiment

Author: Beeman, J. W., Benato, G., Bucci, C., Canonica, L., Carniti, P., Celi, E., Clemenza, M., D'Addabbo, A., Danevich, F. A., Di Domizio, S., Di Lorenzo, S., Dubovik, O. M., Iachellini, N. Ferreiro, Ferroni, F., Fiorini, E., Fu, S., Garai, A., Ghislandi, S., Gironi, L., Gorla, P., Gotti, C., Guillaumon, P. V., Helis, D. L., Kovtun, G. P., Mancuso, M., Marini, L., Olmi, M., Pagnanini, L., Pattavina, L., Pessina, G., Petricca, F., Pirro, S., Pozzi, S., Puiu, A., Quitadamo, S., Rothe, J., Scherban, A. P., Schoenert, S., Solopikhin, D. A., Strauss, R., Tarabini, E., Tretyak, V. I., Tupitsyna, I. A., and Wagner, V.
Subjects: Physics - Instrumentation and Detectors, Astrophysics - Instrumentation and Methods for Astrophysics
Abstract: RES-NOVA is a newly proposed experiment for the detection of neutrinos from astrophysical sources, mainly Supernovae, using an array of cryogenic detectors made of PbWO$_4$ crystals produced from archaeological Pb. This unconventional material, characterized by intrinsic high radiopurity, enables to achieve low-background levels in the region of interest for the neutrino detection via Coherent Elastic neutrino-Nucleus Scattering (CE$\nu$NS). This signal lies at the detector energy threshold, O(1 keV), and it is expected to be hidden by naturally occurring radioactive contaminants of the crystal absorber. Here, we present the results of a radiopurity assay on a 0.84 kg PbWO$_4$ crystal produced from archaeological Pb operated as a cryogenic detector. The crystal internal radioactive contaminations are: $^{232}$Th $<$40 $\mu$Bq/kg, $^{238}$U $<$30 $\mu$Bq/kg, $^{226}$Ra 1.3 mBq/kg and $^{210}$Pb 22.5 mBq/kg. We present also a background projection for the final experiment and possible mitigation strategies for further background suppression. The achieved results demonstrate the feasibility of realizing this new class of detectors., Comment: New analysis with high statistic
Published: 2022
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26. Optimization of the first CUPID detector module

Author: CUPID collaboration, Armatol, A., Augier, C., Avignone III, F. T., Azzolini, O., Balata, M., Ballen, K., Barabash, A. S., Bari, G., Barresi, A., Baudin, D., Bellini, F., Benato, G., Beretta, M., Bettelli, M., Biassoni, M., Billard, J., Boldrini, V., Branca, A., Brofferio, C., Bucci, C., Camilleri, J., Capelli, C., Capelli, S., Cappelli, L., Cardani, L., Carniti, P., Casali, N., Celi, E., Chang, C., Chiesa, D., Clemenza, M., Colantoni, I., Copello, S., Craft, E., Cremonesi, O., Creswick, R. J., Cruciani, A., D'Addabbo, A., D'Imperio, G., Dabagov, S., Dafinei, I., Danevich, F. A., De Jesus, M., de Marcillac, P., Dell'Oro, S., Di Domizio, S., Di Lorenzo, S., Dixon, T., Dompè, V., Drobizhev, A., Dumoulin, L., Fantini, G., Faverzani, M., Ferri, E., Ferri, F., Ferroni, F., Figueroa-Feliciano, E., Foggetta, L., Formaggio, J., Franceschi, A., Fu, C., Fu, S., Fujikawa, B. K., Gallas, A., Gascon, J., Ghislandi, S., Giachero, A., Gianvecchio, A., Gironi, L., Giuliani, A., Gorla, P., Gotti, C., Grant, C., Gras, P., Guillaumon, P. V., Gutierrez, T. D., Han, K., Hansen, E. V., Heeger, K. M., Helis, D. L., Huang, H. Z., Huang, R. G., Imbert, L., Johnston, J., Juillard, A., Karapetrov, G., Keppel, G., Khalife, H., Kobychev, V. V., Kolomensky, Yu. G., Konovalov, S. I., Kowalski, R., Langford, T., Lefevre, M ., Liu, R., Liu, Y., Loaiza, P., Ma, L., Madhukuttan, M., Mancarella, F., Marini, L., Marnieros, S., Martinez, M., Maruyama, R. H., Mas, Ph., Mauri, B., Mayer, D., Mazzitelli, G., Mei, Y., Milana, S., Morganti, S., Napolitano, T., Nastasi, M., Nikkel, J., Nisi, S., Nones, C., Norman, E. B., Novosad, V., Nutini, I., O'Donnell, T., Olivieri, E., Olmi, M., Ouellet, J. L., Pagan, S., Pagliarone, C., Pagnanini, L., Pattavina, L., Pavan, M., Peng, H., Pessina, G., Pettinacci, V., Pira, C., Pirro, S., Poda, D. V., Polischuk, O. G., Ponce, I., Pozzi, S., Previtali, E., Puiu, A., Quitadamo, S., Ressa, A., Rizzoli, R., Rosenfeld, C., Rosier, P., Scarpaci, J., Schmidt, B., Sharma, V., Shlegel, V., Singh, V., Sisti, M., Slocum, P., Speller, D., Surukuchi, P. T., Taffarello, L., Tomei, C., Torres, J., Tretyak, V. I., Tsymbaliuk, A., Velazquez, M., Vetter, K. J., Wagaarachchi, S. L., Wang, G., Wang, L., Wang, R., Welliver, B., Wilson, J., Wilson, K., Winslow, L. A., Xue, M., Yan, L., Yang, J., Yefremenko, V., Umatov, V. I., Zarytskyy, M. M., Zhang, J., Zolotarova, A., and Zucchelli, S.
Subjects: Physics - Instrumentation and Detectors, Nuclear Experiment
Abstract: CUPID will be a next generation experiment searching for the neutrinoless double $\beta$ decay, whose discovery would establish the Majorana nature of the neutrino. Based on the experience achieved with the CUORE experiment, presently taking data at LNGS, CUPID aims to reach a background free environment by means of scintillating Li$_{2}$$^{100}$MoO$_4$ crystals coupled to light detectors. Indeed, the simultaneous heat and light detection allows us to reject the dominant background of $\alpha$ particles, as proven by the CUPID-0 and CUPID-Mo demonstrators. In this work we present the results of the first test of the CUPID baseline module. In particular, we propose a new optimized detector structure and light sensors design to enhance the engineering and the light collection, respectively. We characterized the heat detectors, achieving an energy resolution of (5.9 $\pm$ 0.2) keV FWHM at the $Q$-value of $^{100}$Mo (about 3034 keV). We studied the light collection of the baseline CUPID design with respect to an alternative configuration which features gravity-assisted light detectors' mounting. In both cases we obtained an improvement in the light collection with respect to past measures and we validated the particle identification capability of the detector, which ensures an $\alpha$ particle rejection higher than 99.9%, fully satisfying the requirements for CUPID., Comment: 10 pages, 5 figures
Published: 2022

27. Search for neutrinoless β+EC decay of Te120 with CUORE

Author: Adams, DQ, Alduino, C, Alfonso, K, Avignone, FT, Azzolini, O, Bari, G, Bellini, F, Benato, G, Beretta, M, Biassoni, M, Branca, A, Brofferio, C, Bucci, C, Camilleri, J, Caminata, A, Campani, A, Canonica, L, Cao, XG, Capelli, C, Capelli, S, Cappelli, L, Cardani, L, Carniti, P, Casali, N, Celi, E, Chiesa, D, Clemenza, M, Copello, S, Cremonesi, O, Creswick, RJ, D'Addabbo, A, Dafinei, I, Del Corso, F, Dell'Oro, S, Di Domizio, S, Di Lorenzo, S, Dompè, V, Fang, DQ, Fantini, G, Faverzani, M, Ferri, E, Ferroni, F, Fiorini, E, Franceschi, MA, Freedman, SJ, Fu, SH, Fujikawa, BK, Ghislandi, S, Giachero, A, Gianvecchio, A, Gironi, L, Giuliani, A, Gorla, P, Gotti, C, Gutierrez, TD, Han, K, Hansen, EV, Heeger, KM, Huang, RG, Huang, HZ, Johnston, J, Keppel, G, Kolomensky, Yu G, Kowalski, R, Ligi, C, Liu, R, Ma, L, G., Y, Marini, L, Maruyama, RH, Mayer, D, Mei, Y, Morganti, S, Napolitano, T, Nastasi, M, Nikkel, J, Nones, C, Norman, EB, Nucciotti, A, Nutini, I, O'Donnell, T, Olmi, M, Ouellet, JL, Pagan, S, Pagliarone, CE, Pagnanini, L, Pallavicini, M, Pattavina, L, Pavan, M, Pessina, G, Pettinacci, V, Pira, C, Pirro, S, Pozzi, S, Previtali, E, Puiu, A, Quitadamo, S, Ressa, A, Rosenfeld, C, and Sakai, M
Subjects: Nuclear and Plasma Physics, Particle and High Energy Physics, Synchrotrons and Accelerators, Physical Sciences, Cardiovascular, Nuclear and plasma physics
Abstract: The Cryogenic Underground Observatory for Rare Events (CUORE) is a large-scale cryogenic experiment searching for neutrinoless double-beta decay (0νββ) in Te130. The CUORE detector is made of natural tellurium, providing the possibility of rare event searches on isotopes other than Te130. In this work we describe a search for neutrinoless positron-emitting electron capture (β+EC) decay in Te120 with a total TeO2 exposure of 355.7 kg yr, corresponding to 0.2405 kg yr of Te120. Albeit 0νββ with two final-state electrons represents the most promising channel, the emission of a positron and two 511-keV γ's make 0νβ+EC decay signature extremely clear. To fully exploit the potential offered by the detector modularity we include events with different topology and perform a simultaneous fit of five selected signal signatures. Using blinded data we extract a median exclusion sensitivity of 3.4×1022 yr at 90% credibility interval (C.I.). After unblinding we find no evidence of 0νβ+EC signal and set a 90% C.I. Bayesian lower limit of 2.9×1022 yr on Te120 half-life. This result improves by an order of magnitude the existing limit from the combined analysis of CUORE-0 and Cuoricino.
Published: 2022

28. An acrylic assembly for low temperature detectors

Author: Biassoni, M., Brofferio, C., Faverzani, M., Ferri, E., Ghislandi, S., Milana, S., Nutini, I., Pettinacci, V., Pozzi, S., and Quitadamo, S.
Subjects: Physics - Instrumentation and Detectors, Physics - Applied Physics
Abstract: Thermal detectors are a powerful instrument for the search of rare particle physics events. Inorganic crystals are classically used as thermal detectors held in supporting frames made of copper. In this work a novel approach to the operation of thermal detectors is presented, where TeO2 crystals are cooled down to ~ 10 mK in a light structure built with plastic materials. The advantages of this approach are discussed., Comment: 8 pages, 9 figures
Published: 2021

29. CUORE Opens the Door to Tonne-scale Cryogenics Experiments

Author: CUORE Collaboration, Adams, D. Q., Alduino, C., Alessandria, F., Alfonso, K., Andreotti, E., Avignone III, F. T., Azzolini, O., Balata, M., Bandac, I., Banks, T. I., Bari, G., Barucci, M., Beeman, J. W., Bellini, F., Benato, G., Beretta, M., Bersani, A., Biare, D., Biassoni, M., Bragazzi, F., Branca, A., Brofferio, C., Bryant, A., Buccheri, A., Bucci, C., Bulfon, C., Camacho, A., Camilleri, J., Caminata, A., Campani, A., Canonica, L., Cao, X. G., Capelli, S., Capodiferro, M., Cappelli, L., Cardani, L., Cariello, M., Carniti, P., Carrettoni, M., Casali, N., Cassina, L., Celi, E., Cereseto, R., Ceruti, G., Chiarini, A., Chiesa, D., Chott, N., Clemenza, M., Conventi, D., Copello, S., Cosmelli, C., Cremonesi, O., Crescentini, C., Creswick, R. J., Cushman, J. S., D'Addabbo, A., D'Aguanno, D., Dafinei, I., Datskov, V., Davis, C. J., Del Corso, F., Dell'Oro, S., Deninno, M. M., Di Domizio, S., Dompè, V., Di Vacri, M. L., Di Paolo, L., Drobizhev, A., Ejzak, L., Faccini, R., Fang, D. Q., Fantini, G., Faverzani, M., Ferri, E., Ferroni, F., Fiorini, E., Franceschi, M. A., Freedman, S. J., Fu, S. H., Fujikawa, B. K., Gaigher, R., Ghislandi, S., Giachero, A., Gironi, L., Giuliani, A., Gladstone, L., Goett, J., Gorla, P., Gotti, C., Guandalini, C., Guerzoni, M., Guetti, M., Gutierrez, T. D., Haller, E. E., Han, K., Hansen, E. V., Heeger, K. M., Hennings-Yeomans, R., Hickerson, K. P., Huang, R. G., Huang, H. Z., Iannone, M., Ioannucci, L., Johnston, J., Kadel, R., Keppel, G., Kogler, L., Kolomensky, Yu. G., Leder, A., Ligi, C., Lim, K. E., Liu, R., Ma, L., Ma, Y. G., Maiano, C., Maino, M., Marini, L., Martinez, M., Amaya, C. Martinez, Maruyama, R. H., Mayer, D., Mazza, R., Mei, Y., Moggi, N., Morganti, S., Mosteiro, P. J., Nagorny, S. S., Napolitano, T., Nastasi, M., Nikkel, J., Nisi, S., Nones, C., Norman, E. B., Novati, V., Nucciotti, A., Nutini, I., O'Donnell, T., Olcese, M., Olivieri, E., Orio, F., Orlandi, D., Ouellet, J. L., Pagan, S., Pagliarone, C. E., Pagnanini, L., Pallavicini, M., Palmieri, V., Pattavina, L., Pavan, M., Pedretti, M., Pedrotta, R., Pelosi, A., Perego, M., Pessina, G., Pettinacci, V., Piperno, G., Pira, C., Pirro, S., Pozzi, S., Previtali, E., Puiu, A., Quitadamo, S., Reindl, F., Rimondi, F., Risegari, L., Rosenfeld, C., Rossi, C., Rusconi, C., Sakai, M., Sala, E., Salvioni, C., Sangiorgio, S., Santone, D., Schaeffer, D., Schmidt, B., Schmidt, J., Scielzo, N. D., Sharma, V., Singh, V., Sisti, M., Smith, A. R., Speller, D., Stivanello, F., Surukuchi, P. T., Taffarello, L., Tatananni, L., Tenconi, M., Terranova, F., Tessaro, M., Tomei, C., Ventura, G., Vetter, K. J., Vignati, M., Wagaarachchi, S. L., Wallig, J., Wang, B. S., Wang, H. W., Welliver, B., Wilson, J., Wilson, K., Winslow, L. A., Wise, T., Zanotti, L., Zarra, C., Zhang, G. Q., Zhu, B. X., Zimmermann, S., and Zucchelli, S.
Subjects: Physics - Instrumentation and Detectors, Nuclear Experiment
Abstract: The past few decades have seen major developments in the design and operation of cryogenic particle detectors. This technology offers an extremely good energy resolution - comparable to semiconductor detectors - and a wide choice of target materials, making low temperature calorimetric detectors ideal for a variety of particle physics applications. Rare event searches have continued to require ever greater exposures, which has driven them to ever larger cryogenic detectors, with the CUORE experiment being the first to reach a tonne-scale, mK-cooled, experimental mass. CUORE, designed to search for neutrinoless double beta decay, has been operational since 2017 at a temperature of about 10 mK. This result has been attained by the use of an unprecedentedly large cryogenic infrastructure called the CUORE cryostat: conceived, designed and commissioned for this purpose. In this article the main characteristics and features of the cryogenic facility developed for the CUORE experiment are highlighted. A brief introduction of the evolution of the field and of the past cryogenic facilities are given. The motivation behind the design and development of the CUORE cryogenic facility is detailed as are the steps taken toward realization, commissioning, and operation of the CUORE cryostat. The major challenges overcome by the collaboration and the solutions implemented throughout the building of the cryogenic facility will be discussed along with the potential improvements for future facilities. The success of CUORE has opened the door to a new generation of large-scale cryogenic facilities in numerous fields of science. Broader implications of the incredible feat achieved by the CUORE collaboration on the future cryogenic facilities in various fields ranging from neutrino and dark matter experiments to quantum computing will be examined., Comment: 45 pages, 14 figures
Published: 2021
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30. Latest results from the CUORE experiment

Author: Adams, DQ, Alduino, C, Alfonso, K, Avignone, FT, Azzolini, O, Bari, G, Bellini, F, Benato, G, Beretta, M, Biassoni, M, Branca, A, Brofferio, C, Bucci, C, Camilleri, J, Caminata, A, Campani, A, Canonica, L, Cao, XG, Capelli, S, Capelli, C, Cappelli, L, Cardani, L, Carniti, P, Casali, N, Celi, E, Chiesa, D, Clemenza, M, Copello, S, Cremonesi, O, Creswick, RJ, D'Addabbo, A, Dafinei, I, Dell'Oro, S, Di Domizio, S, Di Lorenzo, S, Dompè, V, Fang, DQ, Fantini, G, Faverzani, M, Ferri, E, Ferroni, F, Fiorini, E, Franceschi, MA, Freedman, SJ, Fu, SH, Fujikawa, BK, Ghislandi, S, Giachero, A, Gironi, L, Giuliani, A, Gorla, P, Gotti, C, Gutierrez, TD, Han, K, Hansen, EV, Heeger, KM, Huang, RG, Huang, HZ, Johnston, J, Keppel, G, Kolomensky, YG, Kowalski, R, Ligi, C, Liu, R, Ma, L, Ma, YG, Marini, L, Maruyama, RH, Mayer, D, Mei, Y, Morganti, S, Napolitano, T, Nastasi, M, Nikkel, J, Nones, C, Norman, EB, Nucciotti, A, Nutini, I, O'Donnell, T, Olmi, M, Ouellet, JL, Pagan, S, Pagliarone, CE, Pagnanini, L, Pallavicini, M, Pattavina, L, Pavan, M, Pessina, G, Pettinacci, V, Pira, C, Pirro, S, Pozzi, S, Previtali, E, Puiu, A, Quitadamo, S, Ressa, A, Rosenfeld, C, Rusconi, C, Sakai, M, and Sangiorgio, S
Abstract: The CUORE experiment is searching for the neutrinoless double β decay of the 130Te using cryogenic calorimeters. The CUORE detector consists of 988 TeO2 crystals packed in 19 towers and placed in a cryogenic facility with a base temperature of 10 mK. Crystals are enriched in the isotope 130Te which is the candidate for the neutrinoless double β decay. It is taking data since 2017 at the Laboratori Nazionali del Gran Sasso in Italy. Such a long operation of a bolometric experiment in stable condition has no precedent: by reaching 1 tonne-year of exposure CUORE set a fundamental milestone for any future experiment using this technology. The CUORE collaboration investigated the neutrinoless double β decay of 130Te exploiting the updated 1 tonne-year of statistics, setting a limit of 2.2 × 1025 yr at the 90% of credibility interval on the half-life, with a median sensitivity of 2.8 × 1025 yr.
Published: 2022

31. Value of intestinal ultrasound in pediatric magnet ingestion: a case report

Author: Bucci, Cristina, Ferrara, Dolores, Quitadamo, Paolo, Del Monaco, Casimiro, Caruso, Flora, Gaglione, Giovanni, Esposito, Francesco, and Caldore, Mariano
Published: 2022
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32. Cyclic vomiting syndrome in children: a nationwide survey of current practice on behalf of the Italian Society of Pediatric Gastroenterology, Hepatology and Nutrition (SIGENP) and Italian Society of Pediatric Neurology (SINP)

Author: Isoldi, Sara, Di Nardo, Giovanni, Mallardo, Saverio, Parisi, Pasquale, Raucci, Umberto, Tambucci, Renato, Quitadamo, Paolo, Salvatore, Silvia, Felici, Enrico, Cisarò, Fabio, Pensabene, Licia, Banzato, Claudia, Strisciuglio, Caterina, Romano, Claudio, Fusco, Patrizia, Rigotti, Francesca, Sansotta, Naire, Caimmi, Silvia, Savasta, Salvatore, Zuin, Giovanna, Di Stefano, Marina, Provera, Silvia, Campanozzi, Angelo, Rossi, Paolo, Gatti, Simona, Corpino, Mara, Alvisi, Patrizia, Martelossi, Stefano, Suppiej, Agnese, Gandullia, Paolo, Verrotti, Alberto, Terrin, Gianluca, Pacenza, Caterina, Fornaroli, Fabiola, Comito, Donatella, D’Arrigo, Stefano, Striano, Pasquale, Raviglione, Federico, Carotenuto, Marco, Orsini, Alessandro, Belcastro, Vincenzo, Di Corcia, Giovanna, Raieli, Vincenzo, Ferilli, Michela Ada Noris, Ruscitto, Claudia, Spadoni, Elisabetta, Grosso, Salvatore, D’Alonzo, Renato, Papa, Amanda, Pavone, Piero, Meli, Mariaclaudia, Velardita, Mario, Mainetti, Martina, Vanacore, Nicola, and Borrelli, Osvaldo
Published: 2022
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33. Central effects of galcanezumab in migraine: a pilot study on Steady State Visual Evoked Potentials and occipital hemodynamic response in migraine patients

Author: de Tommaso, Marina, La Rocca, Marianna, Quitadamo, Silvia Giovanna, Ricci, Katia, Tancredi, Giusy, Clemente, Livio, Gentile, Eleonora, Ammendola, Elena, and Delussi, Marianna
Published: 2022
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34. Optimization of the first CUPID detector module

Author: Alfonso, K., Armatol, A., Augier, C., Avignone, III, F. T., Azzolini, O., Balata, M., Barabash, A. S., Bari, G., Barresi, A., Baudin, D., Bellini, F., Benato, G., Beretta, M., Bettelli, M., Biassoni, M., Billard, J., Boldrini, V., Branca, A., Brofferio, C., Bucci, C., Camilleri, J., Campani, A., Capelli, C., Capelli, S., Cappelli, L., Cardani, L., Carniti, P., Casali, N., Celi, E., Chang, C., Chiesa, D., Clemenza, M., Colantoni, I., Copello, S., Craft, E., Cremonesi, O., Creswick, R. J., Cruciani, A., D’Addabbo, A., D’Imperio, G., Dabagov, S., Dafinei, I., Danevich, F. A., De Jesus, M., de Marcillac, P., Dell’Oro, S., Di Domizio, S., Di Lorenzo, S., Dixon, T., Dompè, V., Drobizhev, A., Dumoulin, L., Fantini, G., Faverzani, M., Ferri, E., Ferri, F., Ferroni, F., Figueroa-Feliciano, E., Foggetta, L., Formaggio, J., Franceschi, A., Fu, C., Fu, S., Fujikawa, B. K., Gallas, A., Gascon, J., Ghislandi, S., Giachero, A., Gianvecchio, A., Gironi, L., Giuliani, A., Gorla, P., Gotti, C., Grant, C., Gras, P., Guillaumon, P. V., Gutierrez, T. D., Han, K., Hansen, E. V., Heeger, K. M., Helis, D. L., Huang, H. Z., Imbert, L., Johnston, J., Juillard, A., Karapetrov, G., Keppel, G., Khalife, H., Kobychev, V. V., Kolomensky, Yu. G., Konovalov, S. I., Kowalski, R., Langford, T., Lefevre, M., Liu, R., Liu, Y., Loaiza, P., Ma, L., Madhukuttan, M., Mancarella, F., Marini, L., Marnieros, S., Martinez, M., Maruyama, R. H., Mas, Ph., Mauri, B., Mayer, D., Mazzitelli, G., Mei, Y., Milana, S., Morganti, S., Napolitano, T., Nastasi, M., Nikkel, J., Nisi, S., Nones, C., Norman, E. B., Novosad, V., Nutini, I., O’Donnell, T., Olivieri, E., Olmi, M., Ouellet, J. L., Pagan, S., Pagliarone, C., Pagnanini, L., Pattavina, L., Pavan, M., Peng, H., Pessina, G., Pettinacci, V., Pira, C., Pirro, S., Poda, D. V., Polischuk, O. G., Ponce, I., Pozzi, S., Previtali, E., Puiu, A., Quitadamo, S., Ressa, A., Rizzoli, R., Rosenfeld, C., Rosier, P., Scarpaci, J., Schmidt, B., Sharma, V., Shlegel, V. N., Singh, V., Sisti, M., Slocum, P., Speller, D., Surukuchi, P. T., Taffarello, L., Tomei, C., Torres, J. A., Tretyak, V. I., Tsymbaliuk, A., Velazquez, M., Vetter, K. J., Wagaarachchi, S. L., Wang, G., Wang, L., Wang, R., Welliver, B., Wilson, J., Wilson, K., Winslow, L. A., Xue, M., Yan, L., Yang, J., Yefremenko, V., Umatov, V. I., Zarytskyy, M. M., Zhang, J., Zolotarova, A., and Zucchelli, S.
Published: 2022
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35. An integrated map of structural variation in 2,504 human genomes.

Author: Sudmant, Peter H, Rausch, Tobias, Gardner, Eugene J, Handsaker, Robert E, Abyzov, Alexej, Huddleston, John, Zhang, Yan, Ye, Kai, Jun, Goo, Fritz, Markus Hsi-Yang, Konkel, Miriam K, Malhotra, Ankit, Stütz, Adrian M, Shi, Xinghua, Casale, Francesco Paolo, Chen, Jieming, Hormozdiari, Fereydoun, Dayama, Gargi, Chen, Ken, Malig, Maika, Chaisson, Mark JP, Walter, Klaudia, Meiers, Sascha, Kashin, Seva, Garrison, Erik, Auton, Adam, Lam, Hugo YK, Mu, Xinmeng Jasmine, Alkan, Can, Antaki, Danny, Bae, Taejeong, Cerveira, Eliza, Chines, Peter, Chong, Zechen, Clarke, Laura, Dal, Elif, Ding, Li, Emery, Sarah, Fan, Xian, Gujral, Madhusudan, Kahveci, Fatma, Kidd, Jeffrey M, Kong, Yu, Lameijer, Eric-Wubbo, McCarthy, Shane, Flicek, Paul, Gibbs, Richard A, Marth, Gabor, Mason, Christopher E, Menelaou, Androniki, Muzny, Donna M, Nelson, Bradley J, Noor, Amina, Parrish, Nicholas F, Pendleton, Matthew, Quitadamo, Andrew, Raeder, Benjamin, Schadt, Eric E, Romanovitch, Mallory, Schlattl, Andreas, Sebra, Robert, Shabalin, Andrey A, Untergasser, Andreas, Walker, Jerilyn A, Wang, Min, Yu, Fuli, Zhang, Chengsheng, Zhang, Jing, Zheng-Bradley, Xiangqun, Zhou, Wanding, Zichner, Thomas, Sebat, Jonathan, Batzer, Mark A, McCarroll, Steven A, 1000 Genomes Project Consortium, Mills, Ryan E, Gerstein, Mark B, Bashir, Ali, Stegle, Oliver, Devine, Scott E, Lee, Charles, Eichler, Evan E, and Korbel, Jan O
Subjects: Genomes Project Consortium, Humans, Genetic Predisposition to Disease, Physical Chromosome Mapping, Sequence Analysis, DNA, Genetics, Medical, Genetics, Population, Genomics, Sequence Deletion, Amino Acid Sequence, Genotype, Haplotypes, Homozygote, Polymorphism, Single Nucleotide, Quantitative Trait Loci, Genome, Human, Molecular Sequence Data, Genetic Variation, Genome-Wide Association Study, Mutation Rate, Sequence Analysis, DNA, Genetics, Medical, Population, Polymorphism, Single Nucleotide, Genome, Human, General Science & Technology
Abstract: Structural variants are implicated in numerous diseases and make up the majority of varying nucleotides among human genomes. Here we describe an integrated set of eight structural variant classes comprising both balanced and unbalanced variants, which we constructed using short-read DNA sequencing data and statistically phased onto haplotype blocks in 26 human populations. Analysing this set, we identify numerous gene-intersecting structural variants exhibiting population stratification and describe naturally occurring homozygous gene knockouts that suggest the dispensability of a variety of human genes. We demonstrate that structural variants are enriched on haplotypes identified by genome-wide association studies and exhibit enrichment for expression quantitative trait loci. Additionally, we uncover appreciable levels of structural variant complexity at different scales, including genic loci subject to clusters of repeated rearrangement and complex structural variants with multiple breakpoints likely to have formed through individual mutational events. Our catalogue will enhance future studies into structural variant demography, functional impact and disease association.
Published: 2015

36. Peer-Led Team Learning: A Prospective Method for Increasing Critical Thinking in Undergraduate Science Courses

Author: Quitadamo, Ian J., Brahler, C. Jayne, and Crouch, Gregory J.
Abstract: Peer-Led Team Learning (PLTL) is a specific form of small group learning recognized by Project Kaleidoscope as best practice pedagogy (Varma-Nelson, 2004). PLTL was first developed by Woodward, Gosser, and Weiner (1993) as an integrated method that promoted discourse and creative problem solving in chemistry at the City College of New York. It is characterized by a cohort-based social learning structure whereby trained undergraduates, or "peer leaders", guide 4-8 less experienced peers toward conceptual understanding through group-focused science and math problem solving. This study examines the impact of PLTL on critical thinking gains in science and math courses at a research university in the Pacific Northwest. Results of this study show that PLTL has a small but positive impact on critical thinking gains in some science courses, and that it improves grade performance and retention in science and math courses, particularly for females. While math students did not show significant critical thinking gains, it is premature to conclude that PLTL does not promote critical thinking in math. Many factors affect the development of critical thinking skills, and more study is necessary to discover their influence. These results indicate PLTL has potential to improve undergraduate critical thinking. (Contains 2 figures and 3 tables.)
Published: 2009

37. Effective Teaching Styles and Instructional Design for Online Learning Environments.

Author: Quitadamo, Ian J. and Brown, Abbie
Abstract: Internet-based, distance learning solutions are finding increased use and may prove effective in facilitating advanced study coursework for remotely located, place-bound students. Despite the current emphasis on distance learning, the conditions for promoting online learning success have not been entirely defined. This paper presents a case study that profiles the teaching challenges and benefits of an online graduate-level Instructional Design course for in-service teachers taught through Western Governors University and Washington State University. The paper addresses some of the teaching challenges for this online instructional experience, focusing specifically on how teaching styles were used to build online learning community, effectively promote productive and satisfying learning interactions, and develop student problem-solving and critical thinking abilities. Also discussed are those instructional design strategies that were repeatedly employed in multiple course sections to increase online student engagement, encourage critical thinking, and enhance student learning. The findings of this study should prove of interest to anyone currently developing or delivering online instruction. (Contains 34 references.) (Author/MES)
Published: 2001

38. Children’s rare disease cohorts: an integrative research and clinical genomics initiative

Author: Rockowitz, Shira, LeCompte, Nicholas, Carmack, Mary, Quitadamo, Andrew, Wang, Lily, Park, Meredith, Knight, Devon, Sexton, Emma, Smith, Lacey, Sheidley, Beth, Field, Michael, Holm, Ingrid A., Brownstein, Catherine A., Agrawal, Pankaj B., Kornetsky, Susan, Poduri, Annapurna, Snapper, Scott B., Beggs, Alan H., Yu, Timothy W., Williams, David A., and Sliz, Piotr
Published: 2020
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39. Failure of preventive treatments in migraine: an observational retrospective study in a tertiary headache center

Author: Delussi, Marianna, Vecchio, Eleonora, Libro, Giuseppe, Quitadamo, Silvia, and de Tommaso, Marina
Published: 2020
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40. Autonomic communication services: a new challenge for software agents

Author: Quitadamo, Raffaele and Zambonelli, Franco
Abstract: Abstract: The continuous growth in ubiquitous and mobile network connectivity, together with the increasing number of networked devices populating our everyday environments, call for a deep rethinking of traditional communication and service architectures. The emerging area of autonomic communication addresses such challenging issues by trying to identify novel flexible network architectures, and by conceiving novel conceptual and practical tools for the design, development, and execution of “autonomic” (i.e., self-organizing, self-adaptive and context-aware) communication services. In this paper, after having introduced the general concepts behind autonomic communication and autonomic communication services, we analyze the key issue of defining suitable “component” models for autonomic communication services, and discuss the strict relation between such models and agent models. On this basis, we survey and compare different approaches, and eventually try to synthesize the key desirable characteristics that one should expect from a general-purpose component model for autonomic communication services. The key message we will try to deliver is that current research in software agents and multi-agent systems have the potential for playing a major role in inspiring and driving the identification of such a model, and more in general for influencing and advancing the whole area of autonomic communication.
Published: 2024
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41. Critical-Thinking Grudge Match: Biology vs. Chemistry--Examining Factors That Affect Thinking Skill in Nonmajors Science

Author: Quitadamo, Ian J., Kurtz, Martha J., Cornell, Caitlyn Nicole, Griffith, Lindsay, Hancock, Julie, and Egbert, Brandi
Abstract: Chemistry students appear to bring significantly higher critical-thinking skill to their nonmajors course than do biology students. Knowing student preconceptions and thinking ability is essential to learning growth and effective teaching. Of the factors investigated, ethnicity and high school physics had the largest impact on critical-thinking skill differences. Years of high school science, GPA, parents' education, and household income, commonly believed to influence academic performance, did not affect critical-thinking differences in this study. These factors should be considered when designing and assessing nonmajors courses in order to maximize learning. (Contains 5 tables and 1 figure.)
Published: 2011
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42. Community-Based Inquiry Improves Critical Thinking in General Education Biology

Author: Quitadamo, Ian J., Faiola, Celia L., and Johnson, James E.
Abstract: National stakeholders are becoming increasingly concerned about the inability of college graduates to think critically. Research shows that, while both faculty and students deem critical thinking essential, only a small fraction of graduates can demonstrate the thinking skills necessary for academic and professional success. Many faculty are considering nontraditional teaching methods that incorporate undergraduate research because they more closely align with the process of doing investigative science. This study compared a research-focused teaching method called community-based inquiry (CBI) with traditional lecture/laboratory in general education biology to discover which method would elicit greater gains in critical thinking. Results showed significant critical-thinking gains in the CBI group but decreases in a traditional group and a mixed CBI/traditional group. Prior critical-thinking skill, instructor, and ethnicity also significantly influenced critical-thinking gains, with nearly all ethnicities in the CBI group outperforming peers in both the mixed and traditional groups. Females, who showed decreased critical thinking in traditional courses relative to males, outperformed their male counterparts in CBI courses. Through the results of this study, it is hoped that faculty who value both research and critical thinking will consider using the CBI method. (Contains 6 tables and 2 figures.)
Published: 2008
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43. A WebQuest for Spatial Skills

Author: Wood, Pamela L., Quitadamo, Ian J., and DePaepe, James L.
Abstract: The WebQuest is a four-step process integrated at appropriate points in the Animal Studies unit. Through the WebQuest, students create a series of habitat maps that build on the knowledge gained from conducting the various activities of the unit. The quest concludes with an evaluation using the WebQuest rubric and an oral presentation of a final collaborative map. In creating the hypothetical habitat, students analyze, evaluate, compare, and contrast each other's work by making and justifying alternative choices. (Contains 3 figures, 1 resource and 2 online resources.)
Published: 2007
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44. Learning to Improve: Using Writing to Increase Critical Thinking Performance in General Education Biology

Author: Quitadamo, Ian J. and Kurtz, Martha J.
Abstract: Increasingly, national stakeholders express concern that U.S. college graduates cannot adequately solve problems and think critically. As a set of cognitive abilities, critical thinking skills provide students with tangible academic, personal, and professional benefits that may ultimately address these concerns. As an instructional method, writing has long been perceived as a way to improve critical thinking. In the current study, the researchers compared critical thinking performance of students who experienced a laboratory writing treatment with those who experienced traditional quiz-based laboratory in a general education biology course. The effects of writing were determined within the context of multiple covariables. Results indicated that the writing group significantly improved critical thinking skills whereas the nonwriting group did not. Specifically, analysis and inference skills increased significantly in the writing group but not the nonwriting group. Writing students also showed greater gains in evaluation skills; however, these were not significant. In addition to writing, prior critical thinking skill and instructor significantly affected critical thinking performance, whereas other covariables such as gender, ethnicity, and age were not significant. With improved critical thinking skill, general education biology students will be better prepared to solve problems as engaged and productive citizens. (Contains 5 tables and 4 figures.)
Published: 2007
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45. Cougars, Curriculum, and Community

Author: Quitadamo, Ian J. and Campanella, Ryan
Abstract: On the eastern edge of the Cascade Mountain range in Washington State, high school biology students have a unique opportunity to study the elusive cougar ("Felis concolor"), a large cat native to the area. Nestled in the Cascade foothills is the city of Cle Elum, a small rural community that is expected to soon experience considerable growth from development of a large resort. The community provides an excellent model for scientific study of native animals; students can study and compare the cougar's habitat and behavior before, during, and after resort development. From an instructional perspective, the study of cougars provides an ideal way to engage both introductory and advanced biology students in interdisciplinary science inquiry and problem solving. In this article, the authors describe the design and implementation of the Cougar Conservation Project (CCP), a problem-based learning (PBL) curriculum that provided students and community members with valuable interdisciplinary learning experiences. (Contains 2 figures.)
Published: 2005

46. Epistasis analysis of microRNAs on pathological stages in colon cancer based on an Empirical Bayesian Elastic Net method

Author: Wen, Jia, Quitadamo, Andrew, Hall, Benika, and Shi, Xinghua
Published: 2017
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47. IPLEX Administration Improves Motor Neuron Survival and Ameliorates Motor Functions in a Severe Mouse Model of Spinal Muscular Atrophy

Author: Murdocca, Michela, Malgieri, Arianna, Luchetti, Andrea, Saieva, Luciano, Dobrowolny, Gabriella, de Leonibus, Elvira, Filareto, Antonio, Quitadamo, Maria Chiara, Novelli, Giuseppe, Musarò, Antonio, and Sangiuolo, Federica
Published: 2012
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48. Autonomic communication services: a new challenge for software agents

Author: Quitadamo, Raffaele and Zambonelli, Franco
Published: 2008
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49. The association of coeliac disease in childhood with functional gastrointestinal disorders: a prospective study in patients fulfilling Rome III criteria

Author: Turco, R., Boccia, G., Miele, E., Giannetti, E., Buonavolontà, R., Quitadamo, P., Auricchio, R., and Staiano, A.
Published: 2011
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50. Is there a relationship between joint hypermobility and gastrointestinal disorders in children?

Author: Quitadamo, Paolo, Thapar, Nikhil, Di Nardo, Giovanni, Pescarin, Matilde, Bertelli, Luca, Tortora, Clelia, Borrelli, Osvaldo, Giorgio, Roberto De, and Staiano, Annamaria
Abstract: Background. The main aim of the study was to assess the association between joint hypermobility (JH) and gastrointestinal (GI) disorders in children. Methods. All children aged 4-17 years attending the clinics of the participating Pediatric Gastroenterology Centres for functional GI disorders (FGIDs) and inflammatory bowel disease (IBD) were screened for joint laxity. JH diagnosis was inferred using the Beighton Score. JHS diagnosis was inferred based on the Brighton Criteria. Rome III Diagnostic Criteria were used to diagnose possible FGIDs. Ulcerative colitis and Crohn's disease diagnoses were made according to the Porto Criteria. Age and sex-matched healthy children were enrolled as controls. Results. One-hundred-seventy children with GI disorders (70 with FGIDs, 50 with Crohn's disease, and 50 with ulcerative colitis) and 100 healthy controls were enrolled in the study. JH was reported in 7/70 (10%) children with FGIDs (p=0.26 compared to controls), 4/50 (8%) children with Crohn's disease (p=0.21 compared to controls) and 15/50 (30%) children with ulcerative colitis (p=0.09 compared to controls; p=0.01 compared to FGIDs; p=0.01 compared to Crohn's). Conclusions. JH is more prevalent in patients suffering from ulcerative colitis compared to the healthy general population, yet the difference did not reach statistical significance. Likely, a proportion of children with ulcerative colitis and JH may show connective tissue abnormalities. However, whether JH can be considered a possible feature of pediatric GI disorders deserves further investigation. [ABSTRACT FROM AUTHOR]
Published: 2021
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