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8 results on '"Prokopiou, Chrystalla"'

1. Real-world data on prognosis and outcome of primary plasma cell leukemia in the era of novel agents: a multicenter national study by the Greek Myeloma Study Group

Author

Katodritou, Eirini, Terpos, Evangelos, Delimpasi, Sossana, Kotsopoulou, Maria, Michalis, Eurydiki, Vadikolia, Chrysanthi, Kyrtsonis, Marie-Christine, Symeonidis, Argiris, Giannakoulas, Nikolaos, Vadikolia, Chrissa, Michael, Michalis, Kalpadakis, Christina, Gougopoulou, Theodora, Prokopiou, Chrystalla, Kaiafa, Georgia, Christoulas, Dimitrios, Gavriatopoulou, Maria, Giannopoulou, Evlampia, Labropoulou, Vasiliki, Verrou, Evgenia, Kastritis, Efstathios, Konstantinidou, Pavlina, Anagnostopoulos, Achilles, and Dimopoulos, Meletios A.

Published
2018
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2. Peritoneal or mesenteric tumours revealing histiocytosis

Author

Cohen-Aubart, Fleur, primary, Ungureanu, Irena, additional, Razanamahery, Jerome, additional, Charlotte, Frédéric, additional, Valmary-Degano, Séverine, additional, Hélias-Rodzewicz, Zofia, additional, Cazals-Hatem, Dominique, additional, Dartigues, Peggy, additional, Delage-Corre, Manuela, additional, Selves, Janick, additional, Tas, Patrick, additional, Humbert, Sebastien, additional, Malakhia, Alexandre, additional, Kunnamo, Merja, additional, Veresezan, Liana, additional, Prokopiou, Chrystalla, additional, Seeber, Andreas, additional, Tazi, Abdellatif, additional, Donadieu, Jean, additional, Lucidarme, Olivier, additional, Haroche, Julien, additional, and Emile, Jean-François, additional

Published
2021
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5. Real-World Data on Clinical Characteristics, Prognosis and Outcome of Primary Plasma Cell Leukemia: A Study of the Greek Myeloma Study Group in the Era of Novel Agents

Author

Katodritou, Eirini Terpos, Evangelos Delimpasi, Sossana and Kotsopoulou, Maria Michalis, Eurydiki Vadikolia, Chrysanthi and Kyrtsonis, Marie-Christine Symeonidis, Argiris Giannakoulas, Nikolaos Vadikolia, Chrissa Michael, Michalis Kalpadakis, Christina Gougopoulou, Theodora Prokopiou, Chrystalla and Kaiafa, Georgia D. Christoulas, Dimitrios Gavriatopoulou, Maria and Giannopoulou, Evlampia Lampropoulou, Vasiliki Verrou, Evgenia Kastritis, Efstathios Konstantinidou, Pavlina and Anagnostopoulos, Achilles Dimopoulos, Meletios A.

Subjects
Health Sciences, Επιστήμες Υγείας
Published
2016

6. Real-World Data on Clinical Characteristics, Prognosis and Outcome of Primary Plasma Cell Leukemia: A Study of the Greek Myeloma Study Group in the Era of Novel Agents

Author

Katodritou, Eirini, primary, Terpos, Evangelos, additional, Delimpasi, Sossana, additional, Kotsopoulou, Maria, additional, Michalis, Eurydiki, additional, Vadikolia, Chrysanthi, additional, Kyrtsonis, Marie-Christine, additional, Symeonidis, Argiris, additional, Giannakoulas, Nikolaos, additional, Vadikolia, Chrissa, additional, Michael, Michalis, additional, Kalpadakis, Christina, additional, Gougopoulou, Theodora, additional, Prokopiou, Chrystalla, additional, Kaiafa, Georgia D, additional, Christoulas, Dimitrios, additional, Gavriatopoulou, Maria, additional, Giannopoulou, Evlampia, additional, Lampropoulou, Vasiliki, additional, Verrou, Evgenia, additional, Kastritis, Efstathios, additional, Konstantinidou, Pavlina, additional, Anagnostopoulos, Achilles, additional, and Dimopoulos, Meletios A, additional

Published
2016
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8. Acute Promyelocytic Leukemia: an Experience on 95 Greek Patients Treated in the All-Trans-Retinoic Acid Era.

Author

Pagoni, Maria, Garofalaki, Maria, Panitsas, Fotios, Manola, Kalliopi, Psarra, Katerina, Economopoulos, Panagiotis, Vourtsi, Aggeliki, Antoniades, Marios, Gkirkas, Kostas, Tzouvara, Evangelia, Katis, Fotis, Prokopiou, Chrystalla, Tziotziou, Irene, Balta, Artemis, Lemissiou, Eleni, Tsirigotis, Panagiotis, Repoussis, Panagiotis, and Harhalakis, Nicolas

Subjects
TREATMENT of acute promyelocytic leukemia, LEUKEMIA, TRETINOIN, DRUG therapy, DISEASE remission, PATIENTS
Abstract

Acute promyelocytic leukemia (APL) is highly curable with the combination of all-trans-retinoic acid (ATRA) and anthracycline based chemotherapy, but the percentage of early deaths remains high. In the present study, we report the clinical, immunophenotypic, cytogenetic and molecular characteristics and outcome of APL patients diagnosed and treated in various Hospitals of Greece and Cyprus. We describe the data of ninety-five APL patients who were diagnosed during the last 15 years. Seven (7.4%) newly diagnosed APL patients died due to intracranial hemorrhage within 72 hours of presentation. All but two patients were induced with ATRA alone or ATRA plus chemotherapy. The early death rate was 14.9%. After induction all 80 evaluable patients achieved complete hematologic remission. The cumulative incidence of relapse was 18.3%. Eight of the ten relapsed patients were successfully salvaged, while both patients with molecularly resistant disease died during salvage treatment. Overall survival (OS) at 5 years was 78.4% and disease free survival (DFS) 73.6%. In multivariate analysis of OS age over 60 years, DIC at diagnosis and marginally major hemorrhage at presentation were identified as adverse prognostic factors. In the subgroup of patients with available data on FLT3 mutation status (49 out of 94), ITD positivity also remained as an independent prognostic factor in the final model of OS, together with major hemorrhage and marginally high Sanz score. We found a close correlation between the CD2 expression and the development of the differentiation syndrome (DS). In conclusion, the main problem in managing patients with APL is still the high early death rate. [ABSTRACT FROM AUTHOR]

Published
2011
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