Search

Your search keyword '"Plourde, Marie"' showing total 27 results
Start Over Author "Plourde, Marie" Search Limiters Full Text
27 results on '"Plourde, Marie"'

1. USP19 deubiquitinase inactivation regulates α-synuclein ubiquitination and inhibits accumulation of Lewy body-like aggregates in mice

Author

Schorova, Lenka, Bedard, Nathalie, Khayachi, Anouar, Ho, Hung-Hsiang, Bolivar-Pedroso, Joao, Huynh, Julie, Piccirelli, Mikaela, Wang, Yifei, Plourde, Marie, Luo, Wen, del Cid-Pellitero, Esther, Shlaifer, Irina, Castellanos-Montiel, María José, Yu, Ziqi, Valenzuela, Dulce Valeria Carrillo, Lacalle-Aurioles, María, Kriz, Anita, Ye, Yihong, Durcan, Thomas M., and Wing, Simon S.

Published
2023
Full Text
View/download PDF

4. Interactions between BRCA2 and RAD51 for promoting homologous recombination in Leishmania infantum

Author

Genois, Marie-Michelle, Mukherjee, Angana, Ubeda, Jean-Michel, Buisson, Rémi, Paquet, Eric, Roy, Gaétan, Plourde, Marie, Coulombe, Yan, Ouellette, Marc, and Masson, Jean-Yves

Subjects
Biochemistry and Cell Biology, Bioinformatics and Computational Biology, Genetics, Biological Sciences, Rare Diseases, Biotechnology, Vector-Borne Diseases, Generic health relevance, Good Health and Well Being, BRCA2 Protein, Computational Biology, DNA, DNA Damage, Gene Silencing, Genes, BRCA2, Homologous Recombination, Leishmania infantum, Phenotype, Protein Binding, Protozoan Proteins, Rad51 Recombinase, Environmental Sciences, Information and Computing Sciences, Developmental Biology, Biological sciences, Chemical sciences, Environmental sciences
Abstract

In most organisms, the primary function of homologous recombination (HR) is to allow genome protection by the faithful repair of DNA double-strand breaks. The vital step of HR is the search for sequence homology, mediated by the RAD51 recombinase, which is stimulated further by proteins mediators such as the tumor suppressor BRCA2. The biochemical interplay between RAD51 and BRCA2 is unknown in Leishmania or Trypanosoma. Here we show that the Leishmania infantum BRCA2 protein possesses several critical features important for the regulation of DNA recombination at the genetic and biochemical level. A BRCA2 null mutant, generated by gene disruption, displayed genomic instability and gene-targeting defects. Furthermore, cytological studies show that LiRAD51 can no longer localize to the nucleus in this mutant. The Leishmania RAD51 and BRCA2 interact together and the purified proteins bind single-strand DNA. Remarkably, LiBRCA2 is a recombination mediator that stimulates the invasion of a resected DNA double-strand break in an undamaged template by LiRAD51 to form a D-loop structure. Collectively, our data show that LiBRCA2 and LiRAD51 promote HR at the genetic and biochemical level in L. infantum, the causative agent of visceral leishmaniasis.

Published
2012

7. Laying Down Paths in Talking with a Dutch Canadian Organizational Communication Ethnographer

Author

Brummans, Boris H. J. M. and Plourde, Marie-Claude

Subjects
qualitative inquiry, Communication constitutive des organisations, mindful organizing, process philosophy, organization ethnography, organizational communication, Communicative constitution of organizations (CCO), communication organisationnelle, recherche qualitative, ethnographie organisationnelle, philosophie processuelle
Abstract

Cette entrevue trace des chemins de Boris Brummans, ethnographe en communication organisationnelle, dans une conversation avec Marie-Claude Plourde. This interview traces the unfolding trajectories of Boris Brummans, an organizational communication ethnographer, in conversation with Marie-Claude Plourde.

Published
2023

8. Tracer des chemins en conversant avec un ethnographe de la communication organisationnelle néerlando-canadien

Author

H. J. M. Brummans, Boris and Plourde, Marie-Claude

Subjects
qualitative inquiry, Communication constitutive des organisations, mindful organizing, process philosophy, organization ethnography, organizational communication, Communicative constitution of organizations (CCO), communication organisationnelle, recherche qualitative, ethnographie organisationnelle, philosophie processuelle
Abstract

Cette entrevue trace des chemins de Boris Brummans, ethnographe en communication organisationnelle, dans une conversation avec Marie-Claude Plourde. This interview traces the unfolding trajectories of Boris Brummans, an organizational communication ethnographer, in conversation with Marie-Claude Plourde.

Published
2023

10. Franck Renucci, Jean-Marc Réol (dir.), « L’artiste, un chercheur pas comme les autres », Hermès : cognition, communication, politique, n° 72, 2015

Author

Plourde, Marie-Claude

Abstract

L’actuel phénomène de globalisation touche nos sociétés de manière multidimensionnelle ; il se manifeste dans les politiques de gouvernance, les politiques économiques, les modes de consommation et, comme l’exprime Dominique Wolton dans l’avant-propos de ce dossier, dans un changement des mœurs. Nous observons ainsi une unification des marchés mondiaux marquée par l’idéologie capitaliste, dont découle notamment une marchandisation de la culture – pour ne pas dire une neutralisation des espace...

Published
2019

11. Architecture et communication. Beyrouth une ville en surimpression

Author

Plourde, Marie-Claude

Subjects
cultural identity, architecture, semiotics, identité culturelle, sémiotique, digital communication, communication numérique, globalisation, globalization
Abstract

L’articulation claire d’une problématique entre architecture et communication, à l’ère numérique, n’est pas chose fréquente. Ce court texte résume la tentative de Joseph Moukarzel, auteur d’Architecture et communication, à pallier cette lacune. À travers l’exemple de Beyrouth, Moukarzel montre les mutations architecturales que subissent actuellement nos villes en réponse au phénomène de globalisation. In this digital era, it remains relatively unusual to articulate and raise issues inherent to the intersection of architecture and communication. This short text relates Joseph Moukarzel’s attempt to address this gap. Through the example of the city of Beirut, in Architecture et communication Moukarzel shows how the phenomenon of globalization is bringing profound architectural changes to our cities.

Published
2018

12. 1-03 Role of Activin A in human cancer cachexia (ACTICA study)

Author

Baracos, Vickie, Muscaritoli, Maurizio, Aversa, Zaira, Rossi Fanelli, Filippo, Loumaye, A, de Barsy, M, Nachit, M, Frateur, L, Lause, P, Van Maanen, A, Thissen, JP, Awasthi, R, Gillis, C, Liberman, S, Stein, B, Charlebois, P, Carli, F, Ahmad, Sultan, Chiche, Dan, Reza Kazemi-Bajestani, Seyyed Mohammad, Becher, Harald, Venner, Peter, North, Scott, Vickie, Baracos, Li, Yi-Ping, Zhang, Guohua, Ma, Jennifer, Hall, Derek, Patel, Devang, Robinson, Samantha, Di Marco, Sergio, Gallouzi, Imed-Eddine, Sartori, Roberta, Penna, Fabio, Costelli, Paola, Sandri, Marco, Gregorevic, Paul, Toth, Michael J, Miller, Mark S, Callahan, Damien M, Couch, Marion E, Dittus, Kim, Sharma, Mridula, Argilés, Josep M, Bedard, N, Wiles, B, Jammoul, S, Miao, M, Wykes, L, Coyne, E, Hallauer, PL, Hastings, KEM, Stretch, C, Baracos, VE, Chevalier, S, Wing, SS, Marchildon, François, Lala, Neena, St-Louis, Catherine, Wiper-Bergeron, Nadine, Santos Silva, Kleiton Augusto, Dong, Jiangling, Tweardy, David J, Mitch, William E, Zhang, Liping, Hall, Derek T, Ma, Jennifer F, Griss, Takla, Jones, Russell G, Marco, Sergio Di, Marks, Daniel L, Rudnicki, Michael A, Laine, Aaron, Narayanan, Sriram, Choy, Hak, Girard, Luc, Gazdar, Adi, Minna, John, Infante, Rodney, Iyengar, Puneeth, Petruzzelli, Michele, Schweiger, Martina, Rincon, Mercedes, Robertson, Graham, Zechner, Rudolf, Wagner, Erwin F, Pin, Fabrizio, Costamagna, Domiziana, Camperi, Andrea, Sampaolesi, Maurilio, He, Wei, Talbert, Erin, Londhe, Priya, Bloomston, Mark, Croce, Carlo, Guttridge, Denis, Breit, Samuel N, Tsai, Vicky WW, Manandhar, Rakesh, Lin, Shu, Sainsbury, Amanda, Brown, David A, Ferrara, Michele, Reano, Simone, Angelino, Elia, Sabry, Omar, Filigheddu, Nicoletta, Graziani, Andrea, Tsoli, Maria, Allen, John, Taylor, Ryland, Scwheiger, Martina, Swarbrick, Michael M, Ehteda, Anahid, Miekle, Peter, Molloy, Mark, Waning, David L, Mohammad, Khalid S, Reiken, Steven, Xie, Wenjun, Marks, Andrew R, Guise, Theresa A, Moya, Rosita, Zhao, Chunfang, Davies, Joanna D, Carson, James, Everett Couch, Marion, Stecher, Michael, El Mouelhi, Mohamed, Tseng, Yu-Chou, Kulp, Samuel K, Lai, I-Lu, Hsu, En-Chi, He, Wei A, Frankhouser, David E, Yan, Pearlly S, Mo, Xiaokui, Lesinski, Gregory B, Marcucci, Guido, Guttridge, Denis C, Bekaii-Saab, Tanios, Chen, Ching-Shih, Haddad, AHI Al, Al-Azwani, EK, Mahamoud, Y, Safi, F, Salhat, H El, Malek, JA, Adrian, TE, Fearon, K, Temel, J, Currow, D, Gleich, L, Friend, J, Abernethy, A, Garcia, Jose M, Dubé, A, Patoine, D, Lemire, BB, Thériault, M-E, Ribeiro, F, Debigaré, R, Maltais, F, Smuder, Ashley J, Min, Kisuk, Kwon, Oh-Sung, Wiggs, Michael P, Sollanenk, Kurt J, Christou, Demetra D, Yoo, Jeung-Ki, Hwang, Moon-Hyon, Szeto, Hazel H, Kavazis, Andreas N, Powers, Scott K, Kroenke, Candyce H, Meyerhardt, Jeffrey A, Kwan, Marilyn L, Prado, Carla, Xiao, Jingjie, Weltzien, Erin, Castillo, Adrienne, Caan, Bette J, Guan, Chen, Giles, Kaitlin, Wing, Simon, Mazurak, Vera, Jagoe, R Thomas, Wiles, Benjamin, Miao, Miao, Coyne, Erin, Larose, Louise, Cybulsky, Andrey V, Wing, Simon S, Marino, Francesco Elia, Risbridger, Gail, Gold, Elspeth, Segatto, Marco, Fittipaldi, Raffaella, Caretti, Giuseppina, Lee, Hwabin, Fu, Dechen, Dwarkasing, JT, Boekschoten, MV, Argilès, JM, van Dijk, M, Busquets, S, Penna, F, Toledo, M, Laviano, A, Witkamp, RF, van Norren, K, Bédard, Nathalie, Plourde, Marie, Chevalier, Stéphanie, Lala-Tabbert, Neena, Marchildon, Francois, Torabi, S, Glare, P, Plodkowski, A, Margaron, Yoran, Fernandes, Mathieu, Morales, Delphine, Poydenot, Pauline, Menager, Pauline, Fuchs, Alexandra, Degot, Sébastien, Calore, Federica, Canella, Alessandro, Croce, Carlo M, Srinivasan, Kalayarasan, Pulliparracharuvil, Suprabha, Meyer, Jeffrey, Scherer, Philipp E, Kambadur, Ravi, Martinelli, Giulia B, Talamini, Laura, Previdi, Sara, Piccirillo, Rosanna, Jafri, Syed H, Previgliano, Carlos, Khandelwal, Keerti, Shi, Runhua, Mills, Glenn, Amato, Robert, Coats, Valérie, Ribeiro, Fernanda, Tremblay, Lise, Lacasse, Yves, Maltais, François, Saey, Didier, AL Vigano, Antonio, Ciutto, Lorella, Tomasso, Jonathan Di, Kilgour, Robert D, Morais, José A, Borod, Manuel, Almasud, A, Giles, K, Baracos, V, Guan, L, Mazurak, V, Khanuja, Jasleen, Gresham, Gillian, Osipov, Arsen, Tan, Carlyn-Rose, Tuli, Richard, Hendifar, Andrew, Narasimhan, Ashok, Greiner, Russell, Yasui, Yutaka, Bathe, Oliver, Fearon, Kenneth, Damaraju, Sambasivarao, Banh, Taylor, Kliewer, Kara, Hsiao, Yung-Hsuan, Belury, Martha A, Caan, Bette, Quesenberry, Charles, Kwan, Marilyn, Prado, Carla MM, Baracos, Vickie E, Birdsell, Laura, Stuyckens, Kim, Park, Youn Choi, Parekh, Trilok, Sawyer, Michael B, Wu, C, Fernandez, SA, Criswell, T, Chidiac, T, Guttridge, D, Villalona-Calero, M, Bekaii-Saab, T, Khan, Sarah, ALVigano, Antonio, Matos-Neto, EM, Figuerêdo, RG, Camargo, RG, Lima, JDCC, Alves, MJ, Riccardi, D, Alcantara, PS, Pinhata, J, Maximiano, L, Seelaender, M, Lamarche, Émilie, Au, Ernie D, Desai, Aditya P, Koniaris, Leonidas G, Zimmers, Teresa A, Manring, Heather, Weisleder, Noah, Okamura, Heidi, Frankhouser, David, Yan, Pearlly, Tomasso, Jonathan di, Fabbro, Egidio G Del, Davis, Mellar P, Fearon, Kenneth CH, Jatoi, Aminah A, Vigano, Antonio, Putman, Ted, Kezhuo, Zhang, Sladek, Robert, Enjiu, LM, Gomes, SP, Matos-Neto, E, Rossi-Fanneli, F, Seelaender, MC, Ebadi, Maryam, Mazurak, Vera C, Bhatia, Nikita, Padliya, Neerav D, Stadler, Volker, Dariani, Maghsoud, Hariri, Robert J, Parker, Valorie A, Matthews, Ryan R, Bonetto, Andrea, Puppa, Melissa, Kang, Kyung Shin, Mohammed, Khalid S, Robling, Alexander G, Toledo, Míriam, Oliva, Francesc, Luque, Melania, Betancourt, Angelica, Marmonti, Enrica, López-Soriano, Francisco J, Busquets, Sílvia, Theal, Rebecca, Jiang, Heng, Sanchez, Anthony, Hussain, Sabah N, Serpe, R, Madeddu, C, Gudiño, V, Gabba, S, Antoni, G, Macciò, A, and Banni, S

Subjects
Abstracts
Published
2015

14. Marie-Claude Plourde, Deleuze and Architecture

Author

Plourde, Marie-Claude

Abstract

Depuis les années 1990, le concept de pli forgé par Deleuze, mais aussi la « paire » formée par Deleuze et Guattari dont les idées font corps, ont fortement imprégné la pensée architecturale. L’utilisation de leurs concepts philosophiques dans ce domaine est très polarisée : ils peuvent aussi bien faire l’objet d’un usage purement formel et opératoire regardant la conception architecturale, que servir de support théorique aux réflexions sur son rôle social. Le recueil d’Hélène Frichot et Step...

Published
2017

15. Collectif, 2016, Qu’est-ce que le développement durable pour les architectes ? Paris, Archibooks et Sautereau Éditeur

Author

Plourde, Marie-Claude

Abstract

Une étude de 2010 diffusée par le Pike Research nous informe que les « bâtiments sont responsables de 49 % de la consommation mondiale en énergie, et de 47 % des émissions de gaz à effet de serre » (p. 5). Un tel constat place nécessairement au cœur de nos préoccupations environnementales nos modes de construction, mais aussi nos modes de vie et de consommation en général. Par conséquent, l’architecte d’aujourd’hui occupe une position cruciale face aux changements climatiques. Son rôle est d’...

Published
2016
Full Text
View/download PDF

19. Genome-Wide Stochastic Adaptive DNA Amplification at Direct and Inverted DNA Repeats in the Parasite Leishmania

Author

Ubeda, Jean-Michel, primary, Raymond, Frédéric, additional, Mukherjee, Angana, additional, Plourde, Marie, additional, Gingras, Hélène, additional, Roy, Gaétan, additional, Lapointe, Andréanne, additional, Leprohon, Philippe, additional, Papadopoulou, Barbara, additional, Corbeil, Jacques, additional, and Ouellette, Marc, additional

Published
2014
Full Text
View/download PDF

24. Genome-Wide Stochastic Adaptive DNA Amplification at Direct and Inverted DNA Repeats in the Parasite Leishmania.

Author

Ubeda, Jean-Michel, Raymond, Frédéric, Mukherjee, Angana, Plourde, Marie, Gingras, Hélène, Roy, Gaétan, Lapointe, Andréanne, Leprohon, Philippe, Papadopoulou, Barbara, Corbeil, Jacques, and Ouellette, Marc

Subjects
MEDICAL parasitology, GENOMES, GLOBAL environmental change, LEISHMANIA, DNA
Abstract

: The human parasite Leishmania uses adaptive gene rearrangements and amplification involving repeated sequences on a genome-wide scale as one strategy to adapt to a changing environment. [ABSTRACT FROM AUTHOR]

Published
2014
Full Text
View/download PDF

25. Parasite Susceptibility to Amphotericin B in Failures of Treatment for Visceral Leishmaniasis in Patients Coinfected with HIV Type 1 and Leishmania infantum.

Author

Lachaud, Laurence, Bourgeois, Nathalie, Plourde, Marie, Leprohon, Philippe, Bastien, Patrick, and Ouellette, Marc

Subjects
AMPHOTERICIN B, VISCERAL leishmaniasis, HIV infections, ANTIRETROVIRAL agents, DENTAL prophylaxis, PROTOZOAN diseases
Abstract

Background. Visceral leishmaniasis (VL) is an opportunistic infection that can occur among patients infected with human immunodeficieny virus type 1 (HIV-1) in areas where both infections are endemic. Highly active antiretroviral therapy has decreased the incidence of VL in southern Europe among HIV-1-infected patients, but VL is still observed among patients with low CD4 cell counts, and most coinfected patients receiving highly active antiretroviral therapy experienced relapse, despite initial treatment with liposomal amphotericin B. Methods. Through long-term monitoring of VL in 10 patients with HIV-1 infection and/or AIDS, we compared parasite strains derived from primary and secondary episodes of VL. All the patients have received many courses of amphotericin B treatment and/or prophylaxis. Results. Through molecular techniques, we have shown that secondary episodes of VL can be attributable to relapse (7 of 10 episodes) or reinfection (3 of 10). We developed an assay to measure amphotericin B susceptibility and found no evidence of decreased susceptibility among strains isolated from patients, some of whom were infected with the same isolate for up to 10 years. Conclusions. This apparent absence of resistance, as determined by in vitro susceptibility testing, has important consequences and suggests that amphotericin B will remain a useful drug of choice against VL, even after repetitive treatments or prophylactic use. [ABSTRACT FROM AUTHOR]

Published
2009
Full Text
View/download PDF

26. Genome-Wide Stochastic Adaptive DNA Amplification at Direct and Inverted DNA Repeats in the Parasite Leishmania.

Author

Ubeda, Jean-Michel, Raymond, Frédéric, Mukherjee, Angana, Plourde, Marie, Gingras, Hélène, Roy, Gaétan, Lapointe, Andréanne, Leprohon, Philippe, Papadopoulou, Barbara, Corbeil, Jacques, and Ouellette, Marc

Subjects
*MEDICAL parasitology, *GENOMES, *GLOBAL environmental change, *LEISHMANIA, *DNA
Abstract

: The human parasite Leishmania uses adaptive gene rearrangements and amplification involving repeated sequences on a genome-wide scale as one strategy to adapt to a changing environment. [ABSTRACT FROM AUTHOR]

Published
2014
Full Text
View/download PDF

27. The AIB1 polyglutamine repeat does not modify breast cancer risk in BRCA1 and BRCA2 mutation carriers.

Author

Spurdle AB, Antoniou AC, Kelemen L, Holland H, Peock S, Cook MR, Smith PL, Greene MH, Simard J, Plourde M, Southey MC, Godwin AK, Beck J, Miron A, Daly MB, Santella RM, Hopper JL, John EM, Andrulis IL, Durocher F, Struewing JP, Easton DF, and Chenevix-Trench G

Subjects
Female, Genetic Predisposition to Disease, Genotype, Histone Acetyltransferases, Humans, Mutation, Nuclear Receptor Coactivator 3, Proportional Hazards Models, Repetitive Sequences, Nucleic Acid, Risk, Acetyltransferases genetics, Breast Neoplasms genetics, Genes, BRCA1, Genes, BRCA2, Oncogene Proteins genetics, Peptides genetics, Polymorphism, Genetic, Trans-Activators genetics
Abstract

This is by far the largest study of its kind to date, and further suggests that AIB1 does not play a substantial role in modifying the phenotype of BRCA1 and BRCA2 carriers. The AIB1 gene encodes the AIB1/SRC-3 steroid hormone receptor coactivator, and amplification of the gene and/or protein occurs in breast and ovarian tumors. A CAG/CAA repeat length polymorphism encodes a stretch of 17 to 29 glutamines in the HR-interacting carboxyl-terminal region of the protein which is somatically unstable in tumor tissues and cell lines. There is conflicting evidence regarding the role of this polymorphism as a modifier of breast cancer risk in BRCA1 and BRCA2 carriers. To further evaluate the evidence for an association between AIB1 glutamine repeat length and breast cancer risk in BRCA1 and BRCA2 mutation carriers, we have genotyped this polymorphism in 1,090 BRCA1 and 661 BRCA2 mutation carriers from Australia, Europe, and North America. There was no evidence for an increased risk associated with AIB1 glutamine repeat length. Given the large sample size, with more than adequate power to detect previously reported effects, we conclude that the AIB1 glutamine repeat does not substantially modify risk of breast cancer in BRCA1 and BRCA2 mutation carriers., ((Cancer Epidemiol Biomarkers Prev 2006;15(1):76-9).)

Published
2006
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results