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863 results on '"Pereira, Alexandre C."'

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1. Genome-wide study investigating effector genes and polygenic prediction for kidney function in persons with ancestry from Africa and the Americas

3. Ancestral diversity improves discovery and fine-mapping of genetic loci for anthropometric traits—The Hispanic/Latino Anthropometry Consortium

4. Stratified analyses refine association between TLR7 rare variants and severe COVID-19

5. Genome-wide association analysis and Mendelian randomization proteomics identify drug targets for heart failure

6. Ancestral diversity improves discovery and fine-mapping of genetic loci for anthropometric traits—The Hispanic/Latino Anthropometry Consortium

7. GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19

8. Discordant clinical features of identical hypertrophic cardiomyopathy twins

9. GATA6 mutations in hiPSCs inform mechanisms for maldevelopment of the heart, pancreas, and diaphragm.

10. Genetic Studies of Hypertrophic Cardiomyopathy in Singaporeans Identify Variants in TNNI3 and TNNT2 that Are Common in Chinese Patients

12. Statistical Workflow for Feature Selection in Human Metabolomics Data.

13. Genome-wide analyses identify SCN5A as a susceptibility locus for premature atrial contraction frequency

15. Statistical Methods and Workflow for Analyzing Human Metabolomics Data

16. Author Correction: GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19

17. Impact of common cardio-metabolic risk factors on fatal and non-fatal cardiovascular disease in Latin America and the Caribbean: an individual-level pooled analysis of 31 cohort studies

18. Valsartan in early-stage hypertrophic cardiomyopathy: a randomized phase 2 trial

19. Computational prediction of protein subdomain stability in MYBPC3 enables clinical risk stratification in hypertrophic cardiomyopathy and enhances variant interpretation

20. Actionable druggable genome-wide Mendelian randomization identifies repurposing opportunities for COVID-19

21. Genetic constraint at single amino acid resolution in protein domains improves missense variant prioritisation and gene discovery.

22. Trends in cardiometabolic risk factors in the Americas between 1980 and 2014: a pooled analysis of population-based surveys

25. Gene-educational attainment interactions in a multi-population genome-wide meta-analysis identify novel lipid loci

26. Impact of SARS‐Cov‐2 infection in patients with hypertrophic cardiomyopathy: results of an international multicentre registry

27. Genetic structure of pharmacogenetic biomarkers in Brazil inferred from a systematic review and population-based cohorts: a RIBEF/EPIGEN-Brazil initiative

28. Contribution of Previously Unrecognized RNA Splice-Altering Variants to Congenital Heart Disease

29. Global distributions of age- and sex-related arterial stiffness: systematic review and meta-analysis of 167 studies with 509,743 participants

32. Quantitative approaches to variant classification increase the yield and precision of genetic testing in Mendelian diseases: the case of hypertrophic cardiomyopathy

33. A Validated Model for Sudden Cardiac Death Risk Prediction in Pediatric Hypertrophic Cardiomyopathy

34. Myosin Sequestration Regulates Sarcomere Function, Cardiomyocyte Energetics, and Metabolism, Informing the Pathogenesis of Hypertrophic Cardiomyopathy

35. Baseline Characteristics of the VANISH Cohort

36. Transforming Growth Factor-β Analysis of the VANISH Trial Cohort

37. Multi-Omics Profiling of Hypertrophic Cardiomyopathy Reveals Altered Mechanisms in Mitochondrial Dynamics and Excitation–Contraction Coupling

38. Erratum: Ancestral diversity improves discovery and fine-mapping of genetic loci for anthropometric traits-The Hispanic/Latino Anthropometry Consortium.

39. A second update on mapping the human genetic architecture of COVID-19

40. Gene-educational attainment interactions in a multi-population genome-wide meta-analysis identify novel lipid loci

41. GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19

42. Diminishing benefits of urban living for children and adolescents’ growth and development

44. Multi-ancestry sleep-by-SNP interaction analysis in 126,926 individuals reveals lipid loci stratified by sleep duration

46. Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity

47. Abstract P675: GlycA, but Not C-reactive Protein is Associated With Baseline Carotid Artery Plaque in the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil)

48. Cardiomyocyte infection by Trypanosoma cruzi promotes innate immune response and glycolysis activation

49. Origin and dynamics of admixture in Brazilians and its effect on the pattern of deleterious mutations

50. Genome-wide association study for Chagas Cardiomyopathy identify a new risk locus on chromosome 18 associated with an immune-related protein and transcriptional signature

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