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1. Normocomplementemic Urticarial Vasculitis Following Influenza Vaccination: A Case Report and Review of the Literature

Author

Mima Y, Ohtsuka T, Ebato I, Nakata Y, Nakazato Y, and Norimatsu Y

Subjects
vaccination, vasculitis, anticardiolipin antibody, molecular mimicry, Medicine (General), R5-920
Abstract

Yoshihito Mima,1,2 Tsutomu Ohtsuka,2 Ippei Ebato,2 Yukihiro Nakata,2 Yoshimasa Nakazato,3 Yuta Norimatsu4 1Department of Dermatology, Tokyo Metropolitan Police Hospital, Tokyo, Japan; 2Department of Dermatology, International University of Health and Welfare Hospital, Tochigi, Japan; 3Department of Diagnostic Pathology, International University of Health and Welfare Hospital, Tochigi, Japan; 4Department of Dermatology, International University of Health and Welfare, Narita Hospital, Chiba, JapanCorrespondence: Yoshihito Mima, Department of Dermatology, Tokyo Metropolitan Police Hospital, 4-22-1 Nakano, Nakano-ku, Tokyo, 164-8541, Japan, Tel +81-03-5343-5611, Fax +81-03-5343-5612, Email yoshihito11.mima@gmail.comAbstract: Urticarial vasculitis is characterized by persistent urticarial lesions lasting over 24 h. Urticarial vasculitis is often triggered by medications, infections, and autoimmune disorders. However, vaccinations against viral and bacterial pathogens have recently been documented to induce urticarial vasculitis. We describe the case of a 67-year-old woman who was presented with an extensive erythematous and purpuric rash without systemic symptoms 3 days after an influenza vaccination. She was diagnosed with normocomplementemic urticarial vasculitis based on clinical findings, normal complement levels, and histopathological findings of leukocytoclastic vasculitis. After receiving oral histamines, she showed complete resolution 3 months after receiving the influenza vaccination. Although vaccination-associated vasculitis is common, urticarial vasculitis following vaccinations is rare. We reviewed 13 cases of urticarial vasculitis following a wide range of vaccines, including those against Bacillus Calmette–Guérin, serogroup B meningococcus, influenza, and coronavirus disease. We conducted a comprehensive review of various aspects, including age, sex, past medical history, type of vaccination, number of vaccinations, onset time, cutaneous symptoms, place of eruption, systemic symptoms, laboratory disorders, treatment period, and treatment of urticarial vasculitis. Two patients developed hypocomplementemic urticarial vasculitis after vaccination, and both experienced systemic symptoms such as arthralgia and fever. In this review, no significant differences were found in the data, which may be attributed to the small number of cases. The mechanisms underlying the induction of urticarial vasculitis by vaccines remain unknown; however, in addition to immune complex deposition and complement activation due to vaccine components, molecular mimicry may trigger urticarial vasculitis by producing vaccine-derived pathogenic antigen antibodies. This case study emphasizes the need for heightened awareness and further investigation of urticarial vasculitis as a rare adverse effect of vaccination.Keywords: vaccination, vasculitis, anticardiolipin antibody, molecular mimicry

Published
2024

5. Socioeconomic variations determine the clinical presentation, aetiology, and outcome of infective endocarditis: a prospective cohort study from the ESC-EORP EURO-ENDO (European Infective Endocarditis) registry

Author

Sengupta, S, Prendergast, B, Laroche, C, Furnaz, S, Ronderos, R, Almaghraby, A, Asch, F, Blechova, K, Zaky, H, Strahilevitz, J, Dworakowski, R, Miyasaka, Y, Sebag, I, Izumi, C, Axler, O, Jamiel, A, Philip, M, Vieira, M, Lancellotti, P, Habib, G, Gale, C, Beleslin, B, Budaj, A, Chioncel, O, Dagres, N, Danchin, N, Emberson, J, Erlinge, D, Glikson, M, Gray, A, Kayikcioglu, M, Maggioni, A, Nagy, V, Nedoshivin, A, Petronio, A, Roos-Hesselink, J, Wallentin, L, Zeymer, U, Cosyns, B, Donal, E, Erba, P, Iung, B, Popescu, B, Tornos, P, Andarala, M, Berle, C, Brunel-Lebecq, A, Fiorucci, E, Missiamenou, V, Taylor, C, Ali Tatar-Chentir, N, Al-Mallah, M, Astrom Aneq, M, Athanassopoulos, G, Badano, L, Benyoussef, S, Calderon Aranda, E, Cardim, N, Chan, K, Cruz, I, Edvardsen, T, Goliasch, G, Hagendorff, A, Hristova, K, Kamp, O, Kang, D, Kong, W, Matskeplishvili, S, Meshaal, M, Mirocevic, M, Neskovic, A, Pazdernik, M, Plonska-Gosciniak, E, Raissouni, M, Sade, L, Sadeghpour, A, Sambola, A, Separovic-Hanzevacki, J, Takeuchi, M, Tucay, E, Tude Rodrigues, A, Varga, A, Vaskelyte, J, Yamagata, K, Yiangou, K, Granada, I, Mahia, M, Ressi, S, Na-Cinovich, F, Iribarren, A, Fernandez Oses, P, Avegliano, G, Filipini, E, Obregon, R, Bangher, M, Dho, J, Cartasegna, L, Plastino, M, Novas, V, Shigel, C, Reyes, G, De Santos, M, Gastaldello, N, Granillo Fernandez, M, Potito, M, Streit-Enberger, G, Velazco, P, Casabe, J, Cortes, C, Guevara, E, Salmo, F, Seijo, M, Weidinger, F, Heger, M, Brooks, R, Stollberger, C, Ho, C, Perschy, L, Puskas, L, Binder, C, Rosenhek, R, Schneider, M, Winter, M, Hoffer, E, Melis-Sopoulou, M, Lecoq, E, Legrand, D, Jacquet, S, Massoz, M, Pierard, L, Marchetta, S, Dulgheru, R, D'Emal, C, Oury, C, Droog-Mans, S, Kerkhove, D, Plein, D, Soens, L, Weytjens, C, Motoc, A, Roosens, B, Lemoine, I, Rodrigus, I, Paelinck, B, Am-Sel, B, Unger, P, Konopnicki, D, Beauloye, C, Pasquet, A, Vanoverschelde, J, Pierard, S, Vancraeynest, D, Sinnaeve, F, Andrade, J, Staszko, K, Dos Santos Monteiro, R, Miglioranza, M, Shuha, D, Alcantara, M, Cravo, V, Fazzio, L, Felix, A, Iso, M, Musa, C, Siciliano, A, Villaca Filho, F, Rodrigues, A, Vilela, F, Braga, J, Silva, R, Rodrigues, D, Silva, L, Morhy, S, Fischer, C, Afonso, T, Abreu, J, Falcao, S, Moises, V, Gou-Vea, A, Mancuso, F, Souza, A, Silva, C, Joao, G, Abboud, C, Bellio de Mattos Barretto, R, Ramos, A, Arnoni, R, Assef, J, Della Togna, D, Le Bihan, D, Miglioli, L, Romero Oliveira, A, Tadeu Magro Kroll, R, Cortez, D, Gelape, C, Peirira Nunes, M, De Abreu Ferrari, T, Hay, K, Le, V, Page, M, Poulin, F, Sauve, C, Serri, K, Mercure, C, Beaudoin, J, Pibarot, P, Rudski, L, Ricafort, G, Barsic, B, Krajinovic, V, Vargovic, M, Lovric, D, Reskovic-Luksic, V, Vincelj, J, Jaksic Jurinjak, S, Yiannikourides, V, Ioannides, M, Pofaides, C, Masoura, V, Pudich, J, Linhart, A, Siranec, M, Marek, J, Kamenik, M, Pelouch, R, Coufal, Z, Mikulica, M, Griva, M, Jancova, E, Mikulcova, M, Taborsky, M, Precek, J, Jecmenova, M, Latal, J, Widimsky, J, Butta, T, Machacek, S, Vancata, R, Spinar, J, Holicka, M, Pow Chon Long, F, Anzules, N, Bajana Carpio, A, Largacha, G, Penaherrera, E, Moreira, D, Mahfouz, E, Elsafty, E, Soliman, A, Zayed, Y, Aboulenein, J, Abdel-Hay, M, Abdelnaby, M, Ahmed, M, Hammad, B, Saleh, Y, Zahran, H, El-Gebaly, O, Saad, A, Ali, M, Zeid, A, El Sharkawy, R, Al Kholy, A, Doss, R, Osama, D, Rizk, H, Elmogy, A, Mishriky, M, Assayag, P, El Hatimi, S, Hubert, S, Casalta, J, Gouriet, F, Arregle, F, Cammilleri, S, Tessonnier, L, Riberi, A, Botelho-Nevers, E, Gagneux-Brunon, A, Pierrard, R, Tulane, C, Campisi, S, Fuzellier, J, Detoc, M, Mehalla, T, Boutoille, D, Lecompte, A, Lefebvre, M, Pattier, S, Al Habash, O, Asseray-Madani, N, Biron, C, Brochard, J, Caillon, J, Cueff, C, Le Tourneau, T, Lecomte, R, Magali Michel, M, Orain, J, Delarue, S, Le Bras, M, Faucher, J, Aboyans, V, Bee-Harry, A, Durox, H, Lacoste, M, Magne, J, Mohty, D, David, A, Pradel, V, Sierra, V, Neykova, A, Bettayeb, B, Elkentaoui, S, Tzvetkov, B, Landry, G, Strady, C, Ainine, K, Baumard, S, Brasselet, C, Tassigny, C, Valente-Pires, V, Lefranc, M, Hoen, B, Lefevre, B, Curlier, E, Callier, C, Fourcade, N, Jobic, Y, Ansard, S, Le Berre, R, Le Ven, F, Pouliquen, M, Prat, G, Le Roux, P, Bouchart, F, Savoure, A, Alarcon, C, Chapuzet, C, Gueit, I, Tribouilloy, C, Bohbot, Y, Peugnet, F, Gun, M, Duval, X, Lescure, X, Ilic-Habensus, E, Sadoul, N, Selton-Suty, C, Alla, F, Goehringer, F, Huttin, O, Chevalier, E, Garcia, R, Le Marcis, V, Tattevin, P, Flecher, E, Revest, M, Chirouze, C, Bouiller, K, Hustache-Mathieu, L, Klopfenstein, T, Moreau, J, Fournier, D, Brunel, A, Lim, P, Oliver, L, Ternacle, J, Moussafeur, A, Chavanet, P, Piroth, L, Salmon-Rousseau, A, Buisson, M, Mahy, S, Martins, C, Go-Hier, S, Baumann, F, Lebras, S, Piper, C, Guckel, D, Borgermann, J, Horstkotte, D, Winkelmann, E, Brockmeier, B, Grey, D, Nick-Enig, G, Schueler, R, Ozturk, C, Stohr, E, Hamm, C, Walther, T, Brandt, R, Fruhauf, A, Hartung, C, Hellner, C, Wild, C, Becker, M, Hamada, S, Kaestner, W, Stangl, K, Knebel, F, Baldenhofer, G, Brecht, A, Dreger, H, Isner, C, Pfafflin, F, Stegemann, M, Zahn, R, Fraiture, B, Kilkowski, C, Karcher, A, Klinger, S, Tolksdorf, H, Tousoulis, D, Aggeli, C, Sideris, S, Venieri, E, Sarri, G, Tsiapras, D, Armenis, I, Koutsiari, A, Floros, G, Grassos, C, Dragasis, S, Rallidis, L, Varlamos, C, Michalis, L, Naka, K, Bechlioulis, A, Kotsia, A, Lakkas, L, Pappas, K, Papadopoulos, C, Kiokas, S, Lioni, A, Misailidou, S, Bar-Betseas, J, Bonou, M, Kapelios, C, Tomprou, I, Zerva, K, Manolis, A, Hamodraka, E, Athanasiou, D, Haralambidis, G, Samaras, H, Poulimenos, L, Nagy, A, Bartykowszki, A, Gara, E, Mungulmare, K, Kasliwal, R, Bansal, M, Ranjan, S, Bhan, A, Kyavar, M, Maleki, M, Noohi Bezanjani, F, Alizadehasl, A, Boudagh, S, Ghavidel, A, Morad-Nejad, P, Pasha, H, Ghadrdoost, B, Gilon, D, Wanounou, M, Israel, S, D'Agostino, C, Colonna, P, De Michele, L, Fumarola, F, Stante, M, Mar-Chionni, N, Scheggi, V, Alterini, B, Del Pace, S, Stefano, P, Sparano, C, Ruozi, N, Tenaglia, R, Muraru, D, Limbruno, U, Cresti, A, Baratta, P, Solari, M, Giannattasio, C, Moreo, A, De Chiara, B, Lopez Montero, B, Musca, F, Orcese, C, Panzeri, F, Spano, F, Russo, C, Alferi, O, De Bonis, M, Chiappetta, S, Del Forno, B, Ripa, M, Scarpellini, P, Tassan Din, C, Castiglioni, B, Pasci-Uta, R, Carletti, S, Ferrara, D, Guffanti, M, Iaci, G, Lapenna, E, Nisi, T, Oltolini, C, Busnardo, E, Pajoro, U, Agricola, E, Meneghin, R, Schiavi, D, Piscione, F, Citro, R, Benvenga, R, Greco, L, Soriente, L, Radano, I, Prota, C, Bellino, M, Di Vece, D, Santini, F, Salsano, A, Olivieri, G, Turrini, F, Messora, R, Tondi, S, Olaru, A, Agnoletto, V, Grassi, L, Leonardi, C, Sansoni, S, Del Ponte, S, Actis Dato, G, De Martino, A, Ohte, N, Kikuchi, S, Wakami, K, Aonuma, K, Seo, Y, Ishizu, T, Machino-Ohtsuka, T, Yamamoto, M, Iida, N, Nakajima, H, Nakagawa, Y, Amano, M, Miyake, M, Takahashi, K, Shiojima, I, Maeba, H, Suwa, Y, Taniguchi, N, Tsujimoto, S, Kitai, T, Ota, M, Yuda, S, Sasaki, S, Hagiwara, N, Yamazaki, K, Ashihara, K, Arai, K, Saitou, C, Saitou, S, Suzuki, G, Shibata, Y, Watanabe, N, Nishino, S, Ashikaga, K, Kuriyama, N, Mahara, K, Okubo, T, Fujimaki, H, Shi-Tan, H, Yamamoto, H, Abe, K, Terada, M, Takanashi, S, Sata, M, Yamada, H, Kusunose, K, Saijo, Y, Seno, H, Yuichiro, O, Onishi, T, Sera, F, Nakatani, S, Mizuno, H, Sengoku, K, Park, S, Eun Kyoung, K, Ga Yeon, L, Hwang, J, Jin-Oh, C, Sang-Chol, L, Sung-A, C, Jang, S, Heo, R, Lee, S, Song, J, Jung, E, Plisiene, J, Dambrauskaite, A, Gruodyte, G, Jonkaitiene, R, Mizariene, V, Atkocaityte, J, Zvirblyte, R, Sow, R, Codreanu, A, Staub, T, Michaux, C, De la Vega, E, Jacobs-Orazi, L, Mallia Azzopardi, C, Xuereb, R, Pis-Copo, T, Farrugia, J, Fenech, M, Pllaha, E, Vella, C, Borg, D, Casha, R, Grib, L, Raevschi, E, Gre-Jdieru, A, Kravcenco, D, Prisacari, E, Samohvalov, E, Samohvalov, S, Sceglova, N, Panfle, E, Cardaniuc, L, Corcea, V, Feodorovici, A, Gaina, V, Girbu, L, Jimbei, P, Balan, G, Cardaniuc, I, Benesco, I, Marian, V, Sumarga, N, Bozovic, B, Bulatovic, N, Lakovic, P, Music, L, Budde, R, Waha-Dat, A, Gamela, T, Meijers, T, Van Melle, J, Deursen, V, Crijns, H, Bekkers, S, Cheriex, E, Gilbers, M, Kietselaer, B, Knackstedt, C, Lorusso, R, Schalla, S, Streukens, S, Chamuleau, S, Cramer, M, Teske, A, Van der Spoel, T, Wind, A, Lokhorst, J, Liesbek, O, Van Heusden, H, Tanis, W, Van der Bilt, I, Vriend, J, De Lange-Van Bruggen, H, Karijodikoro, E, Riezebos, R, van Dongen, E, Schoep, J, Stolk, V, Offstad, J, Beitnes, J, Helle-Valle, T, Skulstad, H, Skardal, R, Qamar, N, Ahmed, B, Butt, M, Khanzada, M, Saghir, T, Wahid, A, Hryniewiecki, T, Szymanski, P, Marzec, K, Misztal-Ogonowska, M, Kosmala, W, Przewlocka-Kosmala, M, Rojek, A, Woznicka, K, Zachwyc, J, Lisowska, A, Kamin-Ska, M, Kasprzak, J, Kowalczyk, E, Strzecka, D, Wejner-Mik, P, Trabulo, M, Freitas, P, Ranchordas, S, Rodrigues, G, Pinto, P, Queiros, C, Azevedo, J, Marques, L, Seabra, D, Branco, L, Cruz, M, Galrinho, A, Moreira, R, Rio, P, Timoteo, A, Selas, M, Carmelo, V, Duque Neves, B, Pereira, H, Guerra, A, Marques, A, Pintassilgo, I, Tomescu, M, Trofenciuc, N, Andor, M, Bordejevic, A, Branea, H, Caruntu, F, Velcean, L, Mavrea, A, Onel, M, Parvanescu, T, Pop, D, Pop-Moldovan, A, Puticiu, M, Cirin, L, Citu, I, Cotoraci, C, Darabantiu, D, Farcas, R, Marincu, I, Ionac, A, Cozma, D, Mornos, C, Goanta, F, Popescu, I, Beyer, R, Mada, R, Rancea, R, Tomoaia, R, Rosianu, H, Stanescu, C, Kobalava, Z, Karaulova, J, Ko-Tova, E, Milto, A, Pisaryuk, A, Povalyaev, N, Sorokina, M, Alrahimi, J, Elshiekh, A, Ahmed, A, Attia, N, Putnikovic, B, Dimic, A, Ivanovic, B, Matic, S, Trifunovic, D, Petrovic, J, Kosevic, D, Stojanovic, I, Petrovic, I, Dabic, P, Milojevic, P, Srdanovic, I, Susak, S, Velicki, L, Vulin, A, Kovacevic, M, Redzek, A, Stefanovic, M, Yeo, T, Poh, K, Vi-Lacosta, I, Ferrera, C, Olmos, C, Abd El-Nasser, M, Calvo Iglesias, F, Bianco-Gonzalez, E, Bravo Amaro, M, Lopez-Rodriguez, E, Lugo Adan, J, Germinas, A, Pazos-Lopez, P, Pereira Loureiro, M, Perez, M, Raposeiras-Roubin, S, Rasheed Yas, S, Suarez-Varela, M, Vasallo Vidal, F, Garcia-Dorado, D, Fernandez-Hidalgo, N, Gonzalez-Alujas, T, Lozano, J, Maisterra, O, Pizzi, N, Rios, R, Bayes-Genis, A, Pedro Botet, L, Vallejo, N, Llibre, C, Mateu, L, Nunez, R, Quesada, D, Berastegui, E, Bosch Portell, D, Aboal Vinas, J, Albert Bertran, X, Brugada Tar-Radellas, R, Loma-Osorio Ricon, P, Tiron de Llano, C, Arnau, M, Bel, A, Blanes, M, Osa, A, Anguita, M, Carrasco, F, Castillo, J, Zamorano, J, Moya Mur, J, Alvaro, M, Fernandez-Golfin, C, Monteagudo, J, Navas Elorza, E, Farinas Alvarez, M, Aguero Balbin, J, Zarauza, J, Gutierrez-Diez, J, Arminanzas, C, Arnaiz de las Revillas, F, Arnaiz Garcia, A, Cobo Belaustegui, M, Fernandez Sampedro, M, Gutierrez Cuadra, M, Garcia Cuello, L, Gonzalez Rico, C, Rodriguez-Alvarez, R, Goikoetxea, J, Montejo, M, Miro, J, Almela, M, Ambrosioni, J, Moreno, A, Quintana, E, Sandoval, E, Tellez, A, Tolosana, J, Vidal, B, Falces, C, Fuster, D, Garcia-De-la-Maria, C, Hernandez-Meneses, M, Llopis, J, Marco, F, Ruiz-Zamora, I, Bardaji Ruiz, A, Sanz Girgas, E, Garcia-Pardo, G, Guillen Marzo, M, Rodriguez Oviedo, A, Villares Jimenez, A, Abid, L, Ham-Mami, R, Kammoun, S, Mourali, M, Mghaieth Zghal, F, Ben Hlima, M, Boudiche, S, Ouali, S, Zakhama, L, Antit, S, Slama, I, Gulel, O, Sahin, M, Karacaglar, E, Kucukoglu, S, Cetinarslan, O, Sinan, U, Canpolat, U, Mutlu, B, Atas, H, Dervishova, R, Ileri, C, Alhashmi, J, Tahir, J, Zarger, P, Baslib, F, Woldman, S, Menezes, L, Primus, C, Uppal, R, Bvekerwa, I, Chandrasekaran, B, Kopanska, A, Chambers, J, Hancock, J, Klein, J, Rajani, R, Ursi, M, Cannata, S, Fife, A, Breeze, J, Browne-Morgan, M, Gunning, M, Streather, S, Zemedkun, M, Alyavi, B, Uzokov, J, Sengupta S. P., Prendergast B., Laroche C., Furnaz S., Ronderos R., Almaghraby A., Asch F. M., Blechova K., Zaky H., Strahilevitz J., Dworakowski R., Miyasaka Y., Sebag I., Izumi C., Axler O., Jamiel A., Philip M., Vieira M. L. C., Lancellotti P., Habib G., Gale C. P., Beleslin B., Budaj A., Chioncel O., Dagres N., Danchin N., Emberson J., Erlinge D., Glikson M., Gray A., Kayikcioglu M., Maggioni A. P., Nagy V. K., Nedoshivin A., Petronio A. -S., Roos-Hesselink J., Wallentin L., Zeymer U., Cosyns B., Donal E., Erba P., Iung B., Popescu B. A., Tornos P., Andarala M., Berle C., Brunel-Lebecq A., Fiorucci E., Missiamenou V., Taylor C., Ali Tatar-Chentir N. N., Al-Mallah M., Astrom Aneq M., Athanassopoulos G., Badano L. P., Benyoussef S., Calderon Aranda E., Cardim N. M., Chan K. -L., Cruz I., Edvardsen T., Goliasch G., Hagendorff A., Hristova K., Kamp O., Kang D. -H., Kong W., Matskeplishvili S., Meshaal M., Mirocevic M., Neskovic A. N., Pazdernik M., Plonska-Gosciniak E., Raissouni M., Sade L. E., Sadeghpour A., Sambola A., Separovic-Hanzevacki J., Takeuchi M., Tucay E., Tude Rodrigues A. C., Varga A., Vaskelyte J., Yamagata K., Yiangou K., Granada I., Mahia M., Ressi S., Na-Cinovich F., Iribarren A., Fernandez Oses P., Avegliano G., Filipini E., Obregon R., Bangher M., Dho J., Cartasegna L., Plastino M. L., Novas V., Shigel C., Reyes G., De Santos M., Gastaldello N., Granillo Fernandez M., Potito M., Streit-Enberger G., Velazco P., Casabe J. H., Cortes C., Guevara E., Salmo F., Seijo M., Weidinger F., Heger M., Brooks R., Stollberger C., Ho C. -Y., Perschy L., Puskas L., Binder C., Rosenhek R., Schneider M., Winter M. -P., Hoffer E., Melis-Sopoulou M., Lecoq E., Legrand D., Jacquet S., Massoz M., Pierard L., Marchetta S., Dulgheru R., D'Emal C., Oury C., Droog-Mans S., Kerkhove D., Plein D., Soens L., Weytjens C., Motoc A., Roosens B., Lemoine I., Rodrigus I., Paelinck B., Am-Sel B., Unger P., Konopnicki D., Beauloye C., Pasquet A., Vanoverschelde J. L., Pierard S., Vancraeynest D., Sinnaeve F., Andrade J. L., Staszko K., Dos Santos Monteiro R., Miglioranza M. H., Shuha D. L., Alcantara M., Cravo V., Fazzio L., Felix A., Iso M., Musa C., Siciliano A. P., Villaca Filho F., Rodrigues A., Vilela F., Braga J., Silva R., Rodrigues D., Silva L., Morhy S., Fischer C., Afonso T., Abreu J., Falcao S. N., Moises V. A., Gou-Vea A., Mancuso F. J., Souza A. C., Silva C. Y., Joao G., Abboud C. S., Bellio de Mattos Barretto R., Ramos A., Arnoni R., Assef J. E., Della Togna D. J., Le Bihan D., Miglioli L., Romero Oliveira A. P., Tadeu Magro Kroll R., Cortez D., Gelape C. L., Peirira Nunes M. D. C., De Abreu Ferrari T. C., Hay K., Le V., Page M., Poulin F., Sauve C., Serri K., Mercure C., Beaudoin J., Pibarot P., Rudski L. G., Ricafort G., Barsic B., Krajinovic V., Vargovic M., Lovric D., Reskovic-Luksic V., Vincelj J., Jaksic Jurinjak S., Yiannikourides V., Ioannides M., Pofaides C., Masoura V., Pudich J., Linhart A., Siranec M., Marek J., Kamenik M., Pelouch R., Coufal Z., Mikulica M., Griva M., Jancova E., Mikulcova M., Taborsky M., Precek J., Jecmenova M., Latal J., Widimsky J., Butta T., Machacek S., Vancata R., Spinar J., Holicka M., Pow Chon Long F., Anzules N., Bajana Carpio A., Largacha G., Penaherrera E., Moreira D., Mahfouz E., Elsafty E., Soliman A., Zayed Y., Aboulenein J., Abdel-Hay M., Abdelnaby M., Ahmed M., Hammad B., Saleh Y., Zahran H., El-Gebaly O., Saad A., Ali M., Zeid A., El Sharkawy R., Al Kholy A., Doss R., Osama D., Rizk H., Elmogy A., Mishriky M., Assayag P., El Hatimi S., Hubert S., Casalta J. -P., Gouriet F., Arregle F., Cammilleri S., Tessonnier L., Riberi A., Botelho-Nevers E., Gagneux-Brunon A., Pierrard R., Tulane C., Campisi S., Fuzellier J. -F., Detoc M., Mehalla T., Boutoille D., Lecompte A. S., Lefebvre M., Pattier S., Al Habash O., Asseray-Madani N., Biron C., Brochard J., Caillon J., Cueff C., Le Tourneau T., Lecomte R., Magali Michel M. M., Orain J., Delarue S., Le Bras M., Faucher J. -F., Aboyans V., Bee-Harry A., Durox H., Lacoste M., Magne J., Mohty D., David A., Pradel V., Sierra V., Neykova A., Bettayeb B., Elkentaoui S., Tzvetkov B., Landry G., Strady C., Ainine K., Baumard S., Brasselet C., Tassigny C., Valente-Pires V., Lefranc M., Hoen B., Lefevre B., Curlier E., Callier C., Fourcade N., Jobic Y., Ansard S., Le Berre R., Le Ven F., Pouliquen M. -C., Prat G., Le Roux P., Bouchart F., Savoure A., Alarcon C., Chapuzet C., Gueit I., Tribouilloy C., Bohbot Y., Peugnet F., Gun M., Duval X., Lescure X., Ilic-Habensus E., Sadoul N., Selton-Suty C., Alla F., Goehringer F., Huttin O., Chevalier E., Garcia R., Le Marcis V., Tattevin P., Flecher E., Revest M., Chirouze C., Bouiller K., Hustache-Mathieu L., Klopfenstein T., Moreau J., Fournier D., Brunel A. -S., Lim P., Oliver L., Ternacle J., Moussafeur A., Chavanet P., Piroth L., Salmon-Rousseau A., Buisson M., Mahy S., Martins C., Go-Hier S., Baumann F., Lebras S., Piper C., Guckel D., Borgermann J., Horstkotte D., Winkelmann E., Brockmeier B., Grey D., Nick-Enig G., Schueler R., Ozturk C., Stohr E., Hamm C., Walther T., Brandt R., Fruhauf A. -C., Hartung C. T., Hellner C., Wild C., Becker M., Hamada S., Kaestner W., Stangl K., Knebel F., Baldenhofer G., Brecht A., Dreger H., Isner C., Pfafflin F., Stegemann M., Zahn R., Fraiture B., Kilkowski C., Karcher A. -K., Klinger S., Tolksdorf H., Tousoulis D., Aggeli C., Sideris S., Venieri E., Sarri G., Tsiapras D., Armenis I., Koutsiari A., Floros G., Grassos C., Dragasis S., Rallidis L., Varlamos C., Michalis L., Naka K., Bechlioulis A., Kotsia A., Lakkas L., Pappas K., Papadopoulos C., Kiokas S., Lioni A., Misailidou S., Bar-Betseas J., Bonou M., Kapelios C., Tomprou I., Zerva K., Manolis A., Hamodraka E., Athanasiou D., Haralambidis G., Samaras H., Poulimenos L., Nagy A., Bartykowszki A., Gara E., Mungulmare K., Kasliwal R., Bansal M., Ranjan S., Bhan A., Kyavar M., Maleki M., Noohi Bezanjani F., Alizadehasl A., Boudagh S., Ghavidel A., Morad-Nejad P., Pasha H. R., Ghadrdoost B., Gilon D., Wanounou M., Israel S., d'Agostino C., Colonna P., De Michele L., Fumarola F., Stante M., Mar-Chionni N., Scheggi V., Alterini B., Del Pace S., Stefano P., Sparano C., Ruozi N., Tenaglia R., Muraru D., Limbruno U., Cresti A., Baratta P., Solari M., Giannattasio C., Moreo A., De Chiara B., Lopez Montero B., Musca F., Orcese C. A., Panzeri F., Spano F., Russo C. F., Alferi O., De Bonis M., Chiappetta S., Del Forno B., Ripa M., Scarpellini P., Tassan Din C., Castiglioni B., Pasci-Uta R., Carletti S., Ferrara D., Guffanti M., Iaci G., Lapenna E., Nisi T., Oltolini C., Busnardo E., Pajoro U., Agricola E., Meneghin R., Schiavi D., Piscione F., Citro R., Benvenga R. M., Greco L., Soriente L., Radano I., Prota C., Bellino M., Di Vece D., Santini F., Salsano A., Olivieri G. M., Turrini F., Messora R., Tondi S., Olaru A., Agnoletto V., Grassi L., Leonardi C., Sansoni S., Del Ponte S., Actis Dato G. M., De Martino A., Ohte N., Kikuchi S., Wakami K., Aonuma K., Seo Y., Ishizu T., Machino-Ohtsuka T., Yamamoto M., Iida N., Nakajima H., Nakagawa Y., Amano M., Miyake M., Takahashi K., Shiojima I., Maeba H., Suwa Y., Taniguchi N., Tsujimoto S., Kitai T., Ota M., Yuda S., Sasaki S., Hagiwara N., Yamazaki K., Ashihara K., Arai K., Saitou C., Saitou S., Suzuki G., Shibata Y., Watanabe N., Nishino S., Ashikaga K., Kuriyama N., Mahara K., Okubo T., Fujimaki H., Shi-Tan H., Yamamoto H., Abe K., Terada M., Takanashi S., Sata M., Yamada H., Kusunose K., Saijo Y., Seno H., Yuichiro O., Onishi T., Sera F., Nakatani S., Mizuno H., Sengoku K., Park S. W., Eun Kyoung K., Ga Yeon L., Hwang J. -W., Jin-Oh C., Park S. -J., Sang-Chol L., Sung-A C., Jang S. Y., Heo R., Lee S., Song J. -M., Jung E., Plisiene J., Dambrauskaite A., Gruodyte G., Jonkaitiene R., Mizariene V., Atkocaityte J., Zvirblyte R., Sow R., Codreanu A., Staub T., Michaux C., De la Vega E. C. L., Jacobs-Orazi L., Mallia Azzopardi C., Xuereb R. G., Pis-Copo T., Farrugia J., Fenech M., Pllaha E., Vella C., Borg D., Casha R., Grib L., Raevschi E., Gre-Jdieru A., Kravcenco D., Prisacari E., Samohvalov E., Samohvalov S., Sceglova N., Panfle E., Cardaniuc L., Corcea V., Feodorovici A., Gaina V., Girbu L., Jimbei P., Balan G., Cardaniuc I., Benesco I., Marian V., Sumarga N., Bozovic B., Bulatovic N., Lakovic P., Music L., Budde R., Waha-Dat A., Gamela T., Meijers T., Van Melle J. P., Deursen V. M., Crijns H. J., Bekkers S. C., Cheriex E. C., Gilbers M., Kietselaer B. L., Knackstedt C., Lorusso R., Schalla S., Streukens S. A., Chamuleau S., Cramer M. -J., Teske A., Van der Spoel T., Wind A., Lokhorst J., Liesbek O., Van Heusden H., Tanis W., Van der Bilt I., Vriend J., De Lange-Van Bruggen H., Karijodikoro E., Riezebos R., van Dongen E., Schoep J., Stolk V., Offstad J. T., Beitnes J. O., Helle-Valle T., Skulstad H., Skardal R., Qamar N., Ahmed B., Butt M. H., Khanzada M. F., Saghir T., Wahid A., Hryniewiecki T., Szymanski P., Marzec K., Misztal-Ogonowska M., Kosmala W., Przewlocka-Kosmala M., Rojek A., Woznicka K., Zachwyc J., Lisowska A., Kamin-Ska M., Kasprzak J. D., Kowalczyk E., Strzecka D. F., Wejner-Mik P., Trabulo M., Freitas P., Ranchordas S., Rodrigues G., Pinto P., Queiros C., Azevedo J., Marques L., Seabra D., Branco L., Cruz M., Galrinho A., Moreira R., Rio P., Timoteo A. T., Selas M., Carmelo V., Duque Neves B., Pereira H., Guerra A., Marques A., Pintassilgo I., Tomescu M. C., Trofenciuc N. -M., Andor M., Bordejevic A., Branea H. S., Caruntu F., Velcean L. A., Mavrea A., Onel M. F., Parvanescu T., Pop D., Pop-Moldovan A. L., Puticiu M. I., Cirin L., Citu I. M., Cotoraci C. 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Abstract

Aims Infective endocarditis (IE) is a life-threatening disease associated with high mortality and morbidity worldwide. We sought to determine how socioeconomic factors might influence its epidemiology, clinical presentation, investigation and management, and outcome, in a large international multicentre registry. Methods and results The EurObservational Programme (EORP) of the European Society of Cardiology EURO-ENDO (European Infective Endocarditis) registry comprises a prospective cohort of 3113 adult patients admitted for IE in 156 hospitals in 40 countries between January 2016 and March 2018. Patients were separated in three groups, according to World Bank economic stratification [group 1: high income (75.6%); group 2: upper-middle income (15.4%); group 3: lower-middle income (9.1%)]. Group 3 patients were younger [median age (interquartile range, IQR): group 1, 66 (53-75) years; group 2, 57 (41-68) years; group 3, 33 (26-43) years; P < 0.001] with a higher frequency of smokers, intravenous drug use, and human immunodeficiency virus infection (all P < 0.001) and presented later [median (IQR) days since symptom onset: group 1, 12 (3-35); group 2, 19 (6-54); group 3, 31 (12-62); P < 0.001] with a higher likelihood of developing congestive heart failure (13.6%, 11.1%, and 22.6%, respectively; P < 0.001) and persistent fever (9.8%, 14.2%, and 27.9%, respectively; P < 0.001). Among 2157 (69.3%) patients with theoretical indication for cardiac surgery, surgery was performed less frequently in group 3 patients (75.5%, 76.8%, and 51.3%, respectively; P < 0.001), who also demonstrated the highest mortality (15.0%, 23.0%, and 23.7%, respectively; P < 0.001). Conclusion Socioeconomic factors influence the clinical profile of patients presenting with IE across the world. Despite younger age, patients from the poorest countries presented with more frequent complications and higher mortality associated with delayed diagnosis and lower use of surgery.

Published
2023

7. Characteristics, management, and outcomes of patients with left-sided infective endocarditis complicated by heart failure: a substudy of the ESC-EORP EURO-ENDO (European infective endocarditis) registry

Author

Bohbot, Y, Habib, G, Laroche, C, Stohr, E, Chirouze, C, Hernandez-Meneses, M, Melissopoulou, M, Mutlu, B, Scheggi, V, Branco, L, Olmos, C, Reyes, G, Pazdernik, M, Iung, B, Sow, R, Mirocevic, M, Lancellotti, P, Tribouilloy, C, Gale, C, Beleslin, B, Budaj, A, Chioncel, O, Dagres, N, Danchin, N, Emberson, J, Erlinge, D, Glikson, M, Gray, A, Kayikcioglu, M, Maggioni, A, Nagy, V, Nedoshivin, A, Petronio, A, Roos-Hesselink, J, Wallentin, L, Zeymer, U, Cosyns, B, Donal, E, Erba, P, Popescu, B, Prendergast, B, Tornos, P, Andarala, M, Berle, C, Brunel-Lebecq, A, Fiorucci, E, Missiamenou, V, Taylor, C, Ali Tatar-Chentir, N, Al-Mallah, M, Astrom Aneq, M, Athanassopoulos, G, Badano, L, Benyoussef, S, Calderon Aranda, E, Cardim, N, Chan, K, Cruz, I, Edvardsen, T, Goliasch, G, Hagendorff, A, Hristova, K, Kamp, O, Kang, D, Kong, W, Matskeplishvili, S, Meshaal, M, Neskovic, A, Plonska-Gosciniak, E, Raissouni, M, Ronderos, R, Sade, L, Sadeghpour, A, Sambola, A, Sengupta, S, Separovic-Hanzevacki, J, Takeuchi, M, Tucay, E, Tude Rodrigues, A, Varga, A, Vaskelyte, J, Yamagata, K, Yiangou, K, Zaky, H, Granada, I, Mahia, M, Ressi, S, Nacinovich, F, Iribarren, A, Fernandez Oses, P, Avegliano, G, Filipini, E, Obregon, R, Bangher, M, Dho, J, Cartasegna, L, Plastino, M, Novas, V, Shigel, C, De Santos, M, Gastaldello, N, Granillo Fernandez, M, Potito, M, Streitenberger, G, Velazco, P, Casabe, J, Cortes, C, Guevara, E, Salmo, F, Seijo, M, Weidinger, F, Heger, M, Brooks, R, Stollberger, C, Ho, C, Perschy, L, Puskas, L, Binder, C, Rosenhek, R, Schneider, M, Winter, M, Hoffer, E, Lecoq, E, Legrand, D, Jacquet, S, Massoz, M, Pierard, L, Marchetta, S, Dulgheru, R, D'Emal, C, Oury, C, Droogmans, S, Kerkhove, D, Plein, D, Soens, L, Weytjens, C, Motoc, A, Roosens, B, Lemoine, I, Rodrigus, I, Paelinck, B, Amsel, B, Unger, P, Konopnicki, D, Beauloye, C, Pasquet, A, Vanoverschelde, J, Pierard, S, Vancraeynest, D, Sinnaeve, F, Andrade, J, Staszko, K, Dos Santos Monteiro, R, Miglioranza, M, Shuha, D, Alcantara, M, Cravo, V, Fazzio, L, Felix, A, Iso, M, Musa, C, Siciliano, A, Villaca Filho, F, Rodrigues, A, Vilela, F, Braga, J, Silva, R, Rodrigues, D, Silva, L, Morhy, S, Fischer, C, Vieira, M, Afonso, T, Abreu, J, Falcao, S, Moises, V, Gouvea, A, Mancuso, F, Souza, A, Silva, C, Joao, G, Abboud, C, Bellio de Mattos Barretto, R, Ramos, A, Arnoni, R, Assef, J, Della Togna, D, Le Bihan, D, Miglioli, L, Romero Oliveira, A, Tadeu Magro Kroll, R, Cortez, D, Gelape, C, Peirira Nunes, M, De Abreu Ferrari, T, Hay, K, Le, V, Page, M, Poulin, F, Sauve, C, Serri, K, Mercure, C, Beaudoin, J, Pibarot, P, Sebag, I, Rudski, L, Ricafort, G, Barsic, B, Krajinovic, V, Vargovic, M, Lovric, D, Reskovic-Luksic, V, Vincelj, J, Jaksic Jurinjak, S, Yiannikourides, V, Ioannides, M, Pofaides, C, Masoura, V, Pudich, J, Linhart, A, Siranec, M, Marek, J, Blechova, K, Kamenik, M, Pelouch, R, Coufal, Z, Mikulica, M, Griva, M, Jancova, E, Mikulcova, M, Taborsky, M, Precek, J, Jecmenova, M, Latal, J, Widimsky, J, Butta, T, Machacek, S, Vancata, R, Spinar, J, Holicka, M, Pow Chon Long, F, Anzules, N, Bajana Carpio, A, Largacha, G, Penaherrera, E, Moreira, D, Mahfouz, E, Elsafty, E, Soliman, A, Zayed, Y, Aboulenein, J, Abdel-Hay, M, Almaghraby, A, Abdelnaby, M, Ahmed, M, Hammad, B, Saleh, Y, Zahran, H, Elgebaly, O, Saad, A, Ali, M, Zeid, A, El Sharkawy, R, Al Kholy, A, Doss, R, Osama, D, Rizk, H, Elmogy, A, Mishriky, M, Assayag, P, El Hatimi, S, Hubert, S, Casalta, J, Gouriet, F, Arregle, F, Cammilleri, S, Tessonnier, L, Riberi, A, Botelho-Nevers, E, Gagneux-Brunon, A, Pierrard, R, Tulane, C, Campisi, S, Fuzellier, J, Detoc, M, Mehalla, T, Boutoille, D, Lecompte, A, Lefebvre, M, Pattier, S, Al Habash, O, Asseray-Madani, N, Biron, C, Brochard, J, Caillon, J, Cueff, C, Le Tourneau, T, Lecomte, R, Magali Michel, M, Orain, J, Delarue, S, Le Bras, M, Faucher, J, Aboyans, V, Beeharry, A, Durox, H, Lacoste, M, Magne, J, Mohty, D, David, A, Pradel, V, Sierra, V, Neykova, A, Bettayeb, B, Elkentaoui, S, Tzvetkov, B, Landry, G, Strady, C, Ainine, K, Baumard, S, Brasselet, C, Tassigny, C, Valente-Pires, V, Lefranc, M, Hoen, B, Lefevre, B, Curlier, E, Callier, C, Fourcade, N, Jobic, Y, Ansard, S, Le Berre, R, Le Ven, F, Pouliquen, M, Prat, G, Le Roux, P, Bouchart, F, Savoure, A, Alarcon, C, Chapuzet, C, Gueit, I, Peugnet, F, Gun, M, Duval, X, Lescure, X, Ilic-Habensus, E, Sadoul, N, Selton-Suty, C, Alla, F, Goehringer, F, Huttin, O, Chevalier, E, Garcia, R, Le Marcis, V, Tattevin, P, Flecher, E, Revest, M, Bouiller, K, Hustache-Mathieu, L, Klopfenstein, T, Moreau, J, Fournier, D, Brunel, A, Lim, P, Oliver, L, Ternacle, J, Moussafeur, A, Chavanet, P, Piroth, L, Salmon-Rousseau, A, Buisson, M, Mahy, S, Martins, C, Gohier, S, Axler, O, Baumann, F, Lebras, S, Piper, C, Guckel, D, Borgermann, J, Horstkotte, D, Winkelmann, E, Brockmeier, B, Grey, D, Nickenig, G, Schueler, R, Ozturk, C, Hamm, C, Walther, T, Brandt, R, Fruhauf, A, Hartung, C, Hellner, C, Wild, C, Becker, M, Hamada, S, Kaestner, W, Stangl, K, Knebel, F, Baldenhofer, G, Brecht, A, Dreger, H, Isner, C, Pfafflin, F, Stegemann, M, Zahn, R, Fraiture, B, Kilkowski, C, Karcher, A, Klinger, S, Tolksdorf, H, Tousoulis, D, Aggeli, C, Sideris, S, Venieri, E, Sarri, G, Tsiapras, D, Armenis, I, Koutsiari, A, Floros, G, Grassos, C, Dragasis, S, Rallidis, L, Varlamos, C, Michalis, L, Naka, K, Bechlioulis, A, Kotsia, A, Lakkas, L, Pappas, K, Papadopoulos, C, Kiokas, S, Lioni, A, Misailidou, S, Barbetseas, J, Bonou, M, Kapelios, C, Tomprou, I, Zerva, K, Manolis, A, Hamodraka, E, Athanasiou, D, Haralambidis, G, Samaras, H, Poulimenos, L, Nagy, A, Bartykowszki, A, Gara, E, Mungulmare, K, Kasliwal, R, Bansal, M, Ranjan, S, Bhan, A, Kyavar, M, Maleki, M, Bezanjani, F, Alizadehasl, A, Boudagh, S, Ghavidel, A, Moradnejad, P, Pasha, H, Ghadrdoost, B, Gilon, D, Strahilevitz, J, Wanounou, M, Israel, S, D'Agostino, C, Colonna, P, De Michele, L, Fumarola, F, Stante, M, Marchionni, N, Alterini, B, Del Pace, S, Stefano, P, Sparano, C, Ruozi, N, Tenaglia, R, Muraru, D, Limbruno, U, Cresti, A, Baratta, P, Solari, M, Giannattasio, C, Moreo, A, De Chiara, B, Lopez Montero, B, Musca, F, Orcese, C, Panzeri, F, Spano, F, Russo, C, Alfieri, O, De Bonis, M, Chiappetta, S, Del Forno, B, Ripa, M, Scarpellini, P, Tassan Din, C, Castiglioni, B, Pasciuta, R, Carletti, S, Ferrara, D, Guffanti, M, Iaci, G, Lapenna, E, Nisi, T, Oltolini, C, Busnardo, E, Pajoro, U, Agricola, E, Meneghin, R, Schiavi, D, Piscione, F, Citro, R, Benvenga, R, Greco, L, Soriente, L, Radano, I, Prota, C, Bellino, M, Di Vece, D, Santini, F, Salsano, A, Olivieri, G, Turrini, F, Messora, R, Tondi, S, Olaru, A, Agnoletto, V, Grassi, L, Leonardi, C, Sansoni, S, Del Ponte, S, Actis Dato, G, De Martino, A, Ohte, N, Kikuchi, S, Wakami, K, Aonuma, K, Seo, Y, Ishizu, T, Machino-Ohtsuka, T, Yamamoto, M, Iida, N, Nakajima, H, Nakagawa, Y, Izumi, C, Amano, M, Miyake, M, Takahashi, K, Shiojima, I, Miyasaka, Y, Maeba, H, Suwa, Y, Taniguchi, N, Tsujimoto, S, Kitai, T, Ota, M, Yuda, S, Sasaki, S, Hagiwara, N, Yamazaki, K, Ashihara, K, Arai, K, Saitou, C, Saitou, S, Suzuki, G, Shibata, Y, Watanabe, N, Nishino, S, Ashikaga, K, Kuriyama, N, Mahara, K, Okubo, T, Fujimaki, H, Shitan, H, Yamamoto, H, Abe, K, Terada, M, Takanashi, S, Sata, M, Yamada, H, Kusunose, K, Saijo, Y, Seno, H, Yuichiro, O, Onishi, T, Sera, F, Nakatani, S, Mizuno, H, Sengoku, K, Park, S, Kyoung, K, Yeon, L, Hwang, J, Jin-Oh, C, Sang-Chol, L, Sung-A, C, Jang, S, Heo, R, Lee, S, Song, J, Jung, E, Plisiene, J, Dambrauskaite, A, Gruodyte, G, Jonkaitiene, R, Mizariene, V, Atkocaityte, J, Zvirblyte, R, Codreanu, A, Staub, T, Michaux, C, De la Vega, E, Jacobs-Orazi, L, Mallia Azzopardi, C, Xuereb, R, Piscopo, T, Farrugia, J, Fenech, M, Pllaha, E, Vella, C, Borg, D, Casha, R, Grib, L, Raevschi, E, Grejdieru, A, Kravcenco, D, Prisacari, E, Samohvalov, E, Samohvalov, S, Sceglova, N, Panfile, E, Cardaniuc, L, Corcea, V, Feodorovici, A, Gaina, V, Girbu, L, Jimbei, P, Balan, G, Cardaniuc, I, Benesco, I, Marian, V, Sumarga, N, Bozovic, B, Bulatovic, N, Lakovic, P, Music, L, Budde, R, Wahadat, A, Gamela, T, Meijers, T, Van Melle, J, Deursen, V, Crijns, H, Bekkers, S, Cheriex, E, Gilbers, M, Kietselaer, B, Knackstedt, C, Lorusso, R, Schalla, S, Streukens, S, Chamuleau, S, Cramer, M, Teske, A, Van der Spoel, T, Wind, A, Lokhorst, J, Liesbek, O, Van Heusden, H, Tanis, W, Van der Bilt, I, Vriend, J, De Lange-van Bruggen, H, Karijodikoro, E, Riezebos, R, van Dongen, E, Schoep, J, Stolk, V, Offstad, J, Beitnes, J, Helle-Valle, T, Skulstad, H, Skardal, R, Qamar, N, Furnaz, S, Ahmed, B, Butt, M, Khanzada, M, Saghir, T, Wahid, A, Hryniewiecki, T, Szymanski, P, Marzec, K, Misztal-Ogonowska, M, Kosmala, W, Przewlocka-Kosmala, M, Rojek, A, Woznicka, K, Zachwyc, J, Lisowska, A, Kaminska, M, Kasprzak, J, Kowalczyk, E, Strzecka, D, Wejner-Mik, P, Trabulo, M, Freitas, P, Ranchordas, S, Rodrigues, G, Pinto, P, Queiros, C, Azevedo, J, Marques, L, Seabra, D, Cruz, M, Galrinho, A, Moreira, R, Rio, P, Timoteo, A, Selas, M, Carmelo, V, Duque Neves, B, Pereira, H, Guerra, A, Marques, A, Pintassilgo, I, Tomescu, M, Trofenciuc, N, Andor, M, Bordejevic, A, Branea, H, Caruntu, F, Velcean, L, Mavrea, A, Onel, M, Parvanescu, T, Pop, D, Pop-Moldovan, A, Puticiu, M, Cirin, L, Citu, I, Cotoraci, C, Darabantiu, D, Farcas, R, Marincu, I, Ionac, A, Cozma, D, Mornos, C, Goanta, F, Popescu, I, Beyer, R, Mada, R, Rancea, R, Tomoaia, R, Rosianu, H, Stanescu, C, Kobalava, Z, Karaulova, J, Kotova, E, Milto, A, Pisaryuk, A, Povalyaev, N, Sorokina, M, Alrahimi, J, Elshiekh, A, Jamiel, A, Ahmed, A, Attia, N, Putnikovic, B, Dimic, A, Ivanovic, B, Matic, S, Trifunovic, D, Petrovic, J, Kosevic, D, Stojanovic, I, Petrovic, I, Dabic, P, Milojevic, P, Srdanovic, I, Susak, S, Velicki, L, Vulin, A, Kovacevic, M, Redzek, A, Stefanovic, M, Yeo, T, Poh, K, Vilacosta, I, Ferrera, C, Abd El- Nasser, M, Calvo Iglesias, F, Blanco-Gonzalez, E, Bravo Amaro, M, Lopez-Rodriguez, E, Lugo Adan, J, Germinas, A, Pazos-Lopez, P, Pereira Loureiro, M, Perez, M, Raposeiras-Roubin, S, Rasheed Yas, S, Suarez-Varela, M, Vasallo Vidal, F, Garcia-Dorado, D, Fernandez-Hidalgo, N, Gonzalez-Alujas, T, Lozano, J, Maisterra, O, Pizzi, N, Rios, R, Bayes-Genis, A, Pedro Botet, L, Vallejo, N, Llibre, C, Mateu, L, Nunez, R, Quesada, D, Berastegui, E, Bosch Portell, D, Aboal Vinas, J, Albert Bertran, X, Brugada Tarradellas, R, Loma-Osorio Ricon, P, Tiron de Llano, C, Arnau, M, Bel, A, Blanes, M, Osa, A, Anguita, M, Carrasco, F, Castillo, J, Zamorano, J, Moya Mur, J, Alvaro, M, Fernandez-Golfin, C, Monteagudo, J, Navas Elorza, E, Farinas Alvarez, M, Aguero Balbin, J, Zarauza, J, Gutierrez-Diez, J, Arminanzas, C, Arnaiz de las Revillas, F, Arnaiz Garcia, A, Cobo Belaustegui, M, Fernandez Sampedro, M, Gutierrez Cuadra, M, Garcia Cuello, L, Gonzalez Rico, C, Rodriguez-Alvarez, R, Goikoetxea, J, Montejo, M, Miro, J, Almela, M, Ambrosioni, J, Moreno, A, Quintana, E, Sandoval, E, Tellez, A, Tolosana, J, Vidal, B, Falces, C, Fuster, D, Garcia-de-la-Maria, C, Llopis, J, Marco, F, Ruiz-Zamora, I, Bardaji Ruiz, A, Sanz Girgas, E, Garcia-Pardo, G, Guillen Marzo, M, Rodriguez Oviedo, A, Villares Jimenez, A, Abid, L, Hammami, R, Kammoun, S, Mourali, M, Mghaieth Zghal, F, Ben Hlima, M, Boudiche, S, Ouali, S, Zakhama, L, Antit, S, Slama, I, Gulel, O, Sahin, M, Karacaglar, E, Kucukoglu, S, Cetinarslan, O, Sinan, U, Canpolat, U, Atas, H, Dervishova, R, Ileri, C, Alhashmi, J, Tahir, J, Zarger, P, Baslib, F, Woldman, S, Menezes, L, Primus, C, Uppal, R, Bvekerwa, I, Chandrasekaran, B, Kopanska, A, Chambers, J, Hancock, J, Klein, J, Rajani, R, Ursi, M, Cannata, S, Dworakowski, R, Fife, A, Breeze, J, Browne-Morgan, M, Gunning, M, Streather, S, Asch, F, Zemedkun, M, Alyavi, B, Uzokov, J, Bohbot Y., Habib G., Laroche C., Stohr E., Chirouze C., Hernandez-Meneses M., Melissopoulou M., Mutlu B., Scheggi V., Branco L., Olmos C., Reyes G., Pazdernik M., Iung B., Sow R., Mirocevic M., Lancellotti P., Tribouilloy C., Gale C. P., Beleslin B., Budaj A., Chioncel O., Dagres N., Danchin N., Emberson J., Erlinge D., Glikson M., Gray A., Kayikcioglu M., Maggioni A. P., Nagy V. K., Nedoshivin A., Petronio A. -S., Roos-Hesselink J., Wallentin L., Zeymer U., Cosyns B., Donal E., Erba P., Popescu B. A., Prendergast B., Tornos P., Andarala M., Berle C., Brunel-Lebecq A., Fiorucci E., Missiamenou V., Taylor C., Ali Tatar-Chentir N. N., Al-Mallah M., Astrom Aneq M., Athanassopoulos G., Badano L., Benyoussef S., Calderon Aranda E., Cardim N. M., Chan K. -L., Cruz I., Edvardsen T., Goliasch G., Hagendorff A., Hristova K., Kamp O., Kang D. -H., Kong W., Matskeplishvili S., Meshaal M., Neskovic A. N., Plonska-Gosciniak E., Raissouni M., Ronderos R., Sade L. E., Sadeghpour A., Sambola A., Sengupta S., Separovic-Hanzevacki J., Takeuchi M., Tucay E., Tude Rodrigues A. C., Varga A., Vaskelyte J., Yamagata K., Yiangou K., Zaky H., Granada I., Mahia M., Ressi S., Nacinovich F., Iribarren A., Fernandez Oses P., Avegliano G., Filipini E., Obregon R., Bangher M., Dho J., Cartasegna L., Plastino M. L., Novas V., Shigel C., De Santos M., Gastaldello N., Granillo Fernandez M., Potito M., Streitenberger G., Velazco P., Casabe J. H., Cortes C., Guevara E., Salmo F., Seijo M., Weidinger F., Heger M., Brooks R., Stollberger C., Ho C. -Y., Perschy L., Puskas L., Binder C., Rosenhek R., Schneider M., Winter M. -P., Hoffer E., Lecoq E., Legrand D., Jacquet S., Massoz M., Pierard L., Marchetta S., Dulgheru R., D'Emal C., Oury C., Droogmans S., Kerkhove D., Plein D., Soens L., Weytjens C., Motoc A., Roosens B., Lemoine I., Rodrigus I., Paelinck B., Amsel B., Unger P., Konopnicki D., Beauloye C., Pasquet A., Vanoverschelde J. L., Pierard S., Vancraeynest D., Sinnaeve F., Andrade J. L., Staszko K., Dos Santos Monteiro R., Miglioranza M. H., Shuha D. L., Alcantara M., Cravo V., Fazzio L., Felix A., Iso M., Musa C., Siciliano A. P., Villaca Filho F., Rodrigues A., Vilela F., Braga J., Silva R., Rodrigues D., Silva L., Morhy S., Fischer C., Vieira M., Afonso T., Abreu J., Falcao S. N., Moises V. A., Gouvea A., Mancuso F. J., Souza A. C., Silva C. Y., Joao G., Abboud C. S., Bellio de Mattos Barretto R., Ramos A., Arnoni R., Assef J. E., Della Togna D. J., Le Bihan D., Miglioli L., Romero Oliveira A. P., Tadeu Magro Kroll R., Cortez D., Gelape C. L., Peirira Nunes M., De Abreu Ferrari T. C., Hay K., Le V., Page M., Poulin F., Sauve C., Serri K., Mercure C., Beaudoin J., Pibarot P., Sebag I. A., Rudski L. G., Ricafort G., Barsic B., Krajinovic V., Vargovic M., Lovric D., Reskovic-Luksic V., Vincelj J., Jaksic Jurinjak S., Yiannikourides V., Ioannides M., Pofaides C., Masoura V., Pudich J., Linhart A., Siranec M., Marek J., Blechova K., Kamenik M., Pelouch R., Coufal Z., Mikulica M., Griva M., Jancova E., Mikulcova M., Taborsky M., Precek J., Jecmenova M., Latal J., Widimsky J., Butta T., Machacek S., Vancata R., Spinar J., Holicka M., Pow Chon Long F., Anzules N., Bajana Carpio A., Largacha G., Penaherrera E., Moreira D., Mahfouz E., Elsafty E., Soliman A., Zayed Y., Aboulenein J., Abdel-Hay M., Almaghraby A., Abdelnaby M., Ahmed M., Hammad B., Saleh Y., Zahran H., Elgebaly O., Saad A., Ali M., Zeid A., El Sharkawy R., Al Kholy A., Doss R., Osama D., Rizk H., Elmogy A., Mishriky M., Assayag P., El Hatimi S., Hubert S., Casalta J. -P., Gouriet F., Arregle F., Cammilleri S., Tessonnier L., Riberi A., Botelho-Nevers E., Gagneux-Brunon A., Pierrard R., Tulane C., Campisi S., Fuzellier J. -F., Detoc M., Mehalla T., Boutoille D., Lecompte A. S., Lefebvre M., Pattier S., Al Habash O., Asseray-Madani N., Biron C., Brochard J., Caillon J., Cueff C., Le Tourneau T., Lecomte R., Magali Michel M. M., Orain J., Delarue S., Le Bras M., Faucher J. -F., Aboyans V., Beeharry A., Durox H., Lacoste M., Magne J., Mohty D., David A., Pradel V., Sierra V., Neykova A., Bettayeb B., Elkentaoui S., Tzvetkov B., Landry G., Strady C., Ainine K., Baumard S., Brasselet C., Tassigny C., Valente-Pires V., Lefranc M., Hoen B., Lefevre B., Curlier E., Callier C., Fourcade N., Jobic Y., Ansard S., Le Berre R., Le Ven F., Pouliquen M. -C., Prat G., Le Roux P., Bouchart F., Savoure A., Alarcon C., Chapuzet C., Gueit I., Peugnet F., Gun M., Duval X., Lescure X., Ilic-Habensus E., Sadoul N., Selton-Suty C., Alla F., Goehringer F., Huttin O., Chevalier E., Garcia R., Le Marcis V., Tattevin P., Flecher E., Revest M., Bouiller K., Hustache-Mathieu L., Klopfenstein T., Moreau J., Fournier D., Brunel A. -S., Lim P., Oliver L., Ternacle J., Moussafeur A., Chavanet P., Piroth L., Salmon-Rousseau A., Buisson M., Mahy S., Martins C., Gohier S., Axler O., Baumann F., Lebras S., Piper C., Guckel D., Borgermann J., Horstkotte D., Winkelmann E., Brockmeier B., Grey D., Nickenig G., Schueler R., Ozturk C., Hamm C., Walther T., Brandt R., Fruhauf A. -C., Hartung C. T., Hellner C., Wild C., Becker M., Hamada S., Kaestner W., Stangl K., Knebel F., Baldenhofer G., Brecht A., Dreger H., Isner C., Pfafflin F., Stegemann M., Zahn R., Fraiture B., Kilkowski C., Karcher A. -K., Klinger S., Tolksdorf H., Tousoulis D., Aggeli C., Sideris S., Venieri E., Sarri G., Tsiapras D., Armenis I., Koutsiari A., Floros G., Grassos C., Dragasis S., Rallidis L., Varlamos C., Michalis L., Naka K., Bechlioulis A., Kotsia A., Lakkas L., Pappas K., Papadopoulos C., Kiokas S., Lioni A., Misailidou S., Barbetseas J., Bonou M., Kapelios C., Tomprou I., Zerva K., Manolis A., Hamodraka E., Athanasiou D., Haralambidis G., Samaras H., Poulimenos L., Nagy A., Bartykowszki A., Gara E., Mungulmare K., Kasliwal R., Bansal M., Ranjan S., Bhan A., Kyavar M., Maleki M., Bezanjani F. N., Alizadehasl A., Boudagh S., Ghavidel A., Moradnejad P., Pasha H. R., Ghadrdoost B., Gilon D., Strahilevitz J., Wanounou M., Israel S., d'Agostino C., Colonna P., De Michele L., Fumarola F., Stante M., Marchionni N., Alterini B., Del Pace S., Stefano P., Sparano C., Ruozi N., Tenaglia R., Muraru D., Limbruno U., Cresti A., Baratta P., Solari M., Giannattasio C., Moreo A., De Chiara B., Lopez Montero B., Musca F., Orcese C. A., Panzeri F., Spano F., Russo C. F., Alfieri O., De Bonis M., Chiappetta S., Del Forno B., Ripa M., Scarpellini P., Tassan Din C., Castiglioni B., Pasciuta R., Carletti S., Ferrara D., Guffanti M., Iaci G., Lapenna E., Nisi T., Oltolini C., Busnardo E., Pajoro U., Agricola E., Meneghin R., Schiavi D., Piscione F., Citro R., Benvenga R. M., Greco L., Soriente L., Radano I., Prota C., Bellino M., Di Vece D., Santini F., Salsano A., Olivieri G. M., Turrini F., Messora R., Tondi S., Olaru A., Agnoletto V., Grassi L., Leonardi C., Sansoni S., Del Ponte S., Actis Dato G. M., De Martino A., Ohte N., Kikuchi S., Wakami K., Aonuma K., Seo Y., Ishizu T., Machino-Ohtsuka T., Yamamoto M., Iida N., Nakajima H., Nakagawa Y., Izumi C., Amano M., Miyake M., Takahashi K., Shiojima I., Miyasaka Y., Maeba H., Suwa Y., Taniguchi N., Tsujimoto S., Kitai T., Ota M., Yuda S., Sasaki S., Hagiwara N., Yamazaki K., Ashihara K., Arai K., Saitou C., Saitou S., Suzuki G., Shibata Y., Watanabe N., Nishino S., Ashikaga K., Kuriyama N., Mahara K., Okubo T., Fujimaki H., Shitan H., Yamamoto H., Abe K., Terada M., Takanashi S., Sata M., Yamada H., Kusunose K., Saijo Y., Seno H., Yuichiro O., Onishi T., Sera F., Nakatani S., Mizuno H., Sengoku K., Park S. W., Kyoung K. E., Yeon L. G., Hwang J. -W., Jin-Oh C., Park S. -J., Sang-Chol L., Sung-A C., Jang S. Y., Heo R., Lee S., Song J. -M., Jung E., Plisiene J., Dambrauskaite A., Gruodyte G., Jonkaitiene R., Mizariene V., Atkocaityte J., Zvirblyte R., Codreanu A., Staub T., Michaux C., De la Vega E. C. L., Jacobs-Orazi L., Mallia Azzopardi C., Xuereb R. G., Piscopo T., Farrugia J., Fenech M., Pllaha E., Vella C., Borg D., Casha R., Grib L., Raevschi E., Grejdieru A., Kravcenco D., Prisacari E., Samohvalov E., Samohvalov S., Sceglova N., Panfile E., Cardaniuc L., Corcea V., Feodorovici A., Gaina V., Girbu L., Jimbei P., Balan G., Cardaniuc I., Benesco I., Marian V., Sumarga N., Bozovic B., Bulatovic N., Lakovic P., Music L., Budde R., Wahadat A., Gamela T., Meijers T., Van Melle J. P., Deursen V. M., Crijns H. J., Bekkers S. C., Cheriex E. C., Gilbers M., Kietselaer B. L., Knackstedt C., Lorusso R., Schalla S., Streukens S. A., Chamuleau S., Cramer M. -J., Teske A., Van der Spoel T., Wind A., Lokhorst J., Liesbek O., Van Heusden H., Tanis W., Van der Bilt I., Vriend J., De Lange-van Bruggen H., Karijodikoro E., Riezebos R., van Dongen E., Schoep J., Stolk V., Offstad J. T., Beitnes J. O., Helle-Valle T., Skulstad H., Skardal R., Qamar N., Furnaz S., Ahmed B., Butt M. H., Khanzada M. 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A., Darabantiu D., Farcas R., Marincu I., Ionac A., Cozma D., Mornos C., Goanta F., Popescu I., Beyer R., Mada R., Rancea R., Tomoaia R., Rosianu H., Stanescu C., Kobalava Z., Karaulova J., Kotova E., Milto A., Pisaryuk A., Povalyaev N., Sorokina M., Alrahimi J., Elshiekh A., Jamiel A., Ahmed A., Attia N., Putnikovic B., Dimic A., Ivanovic B., Matic S., Trifunovic D., Petrovic J., Kosevic D., Stojanovic I., Petrovic I., Dabic P., Milojevic P., Srdanovic I., Susak S., Velicki L., Vulin A., Kovacevic M., Redzek A., Stefanovic M., Yeo T. C., Kong W. K. F., Poh K. K., Vilacosta I., Ferrera C., Abd El- Nasser M., Calvo Iglesias F., Blanco-Gonzalez E., Bravo Amaro M., Lopez-Rodriguez E., Lugo Adan J., Germinas A. N., Pazos-Lopez P., Pereira Loureiro M., Perez M. T., Raposeiras-Roubin S., Rasheed Yas S., Suarez-Varela M. -M., Vasallo Vidal F., Garcia-Dorado D., Fernandez-Hidalgo N., Gonzalez-Alujas T., Lozano J., Maisterra O., Pizzi N., Rios R., Bayes-Genis A., Pedro Botet L., Vallejo N., Llibre C., Mateu L., Nunez R., Quesada D., Berastegui E., Bosch Portell D., Aboal Vinas J., Albert Bertran X., Brugada Tarradellas R., Loma-Osorio Ricon P., Tiron de Llano C., Arnau M. A., Bel A., Blanes M., Osa A., Anguita M., Carrasco F., Castillo J. C., Zamorano J. L., Moya Mur J. L., Alvaro M., Fernandez-Golfin C., Monteagudo J. M., Navas Elorza E., Farinas Alvarez M. C., Aguero Balbin J., Zarauza J., Gutierrez-Diez J. F., Arminanzas C., Arnaiz de las Revillas F., Arnaiz Garcia A., Cobo Belaustegui M., Fernandez Sampedro M., Gutierrez Cuadra M., Garcia Cuello L., Gonzalez Rico C., Rodriguez-Alvarez R., Goikoetxea J., Montejo M., Miro J. M., Almela M., Ambrosioni J., Moreno A., Quintana E., Sandoval E., Tellez A., Tolosana J. 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Abstract

Aims: To evaluate the current management and survival of patients with left-sided infective endocarditis (IE) complicated by congestive heart failure (CHF) in the ESC-EORP European Endocarditis (EURO-ENDO) registry. Methods and results: Among the 3116 patients enrolled in this prospective registry, 2449 (mean age: 60 years, 69% male) with left-sided (native or prosthetic) IE were included in this study. Patients with CHF (n = 698, 28.5%) were older, with more comorbidity and more severe valvular damage (mitro-aortic involvement, vegetations >10 mm and severe regurgitation/new prosthesis dehiscence) than those without CHF (all p ≤ 0.019). Patients with CHF experienced higher 30-day and 1-year mortality than those without (20.5% vs. 9.0% and 36.1% vs. 19.3%, respectively) and CHF remained strongly associated with 30-day (odds ratio[OR] 2.37, 95% confidence interval [CI] [1.73–3.24; p < 0.001) and 1-year mortality (hazard ratio [HR] 1.69, 95% CI 1.39–2.05; p < 0.001) after adjustment for established outcome predictors, including early surgery, or after propensity matching for age, sex, and comorbidity (n = 618 [88.5%] for each group, both p < 0.001). Early surgery, performed on 49% of these patients with IE complicated by CHF, remained associated with a substantial reduction in 30-day mortality following multivariable analysis, after adjustment for age, sex, Charlson comorbidity index, cerebrovascular accident, Staphylococcus aureus IE, streptococcal IE, uncontrolled infection, vegetation size >10 mm, severe valvular regurgitation and/or new prosthetic dehiscence, perivalvular complication, and prosthetic IE (OR 0.22, 95% CI 0.12–0.38; p < 0.001) and in 1-year mortality (HR 0.29, 95% CI 0.20–0.41; p < 0.001). Conclusion: Congestive heart failure is common in left-sided IE and is associated with older age, greater comorbidity, more advanced lesions, and markedly higher 30-day and 1-year mortality. Early surgery is strongly associated with lower mort

Published
2022

8. Correction to: Surgery and outcome of infective endocarditis in octogenarians: prospective data from the ESC EORP EURO-ENDO registry (Infection, (2022), 50, 5, (1191-1202), 10.1007/s15010-022-01792-0)

Author

Pazdernik M., Pazdernik, M, Iung, B, Mutlu, B, Alla, F, Riezebos, R, Kong, W, Nunes, M, Pierard, L, Srdanovic, I, Yamada, H, De Martino, A, Miglioranza, M, Magne, J, Piper, C, Laroche, C, Maggioni, A, Lancellotti, P, Habib, G, Selton-Suty, C, Ronderos, R, Avegliano, G, Oses, P, Filipini, E, Granada, I, Iribarren, A, Mahia, M, Nacinovich, F, Ressi, S, Obregon, R, Bangher, M, Dho, J, Cartasegna, L, Plastino, M, Novas, V, Shigel, C, Reyes, G, De Santos, M, Gastaldello, N, Fernandez, M, Potito, M, Streitenberger, G, Velazco, P, Casabe, J, Cortes, C, Guevara, E, Salmo, F, Seijo, M, Weidinger, F, Heger, M, Brooks, R, Stollberger, C, Ho, C, Perschy, L, Puskas, L, Goliasch, G, Binder, C, Rosenhek, R, Schneider, M, Winter, M, Hoffer, E, Melissopoulou, M, Lecoq, E, Legrand, D, Jacquet, S, Massoz, M, Dulgheru, R, Marchetta, S, D'Emal, C, Oury, C, Cosyns, B, Droogmans, S, Kerkhove, D, Motoc, A, Plein, D, Roosens, B, Soens, L, Weytjens, C, Lemoine, I, Rodrigus, I, Paelinck, B, Amsel, B, Unger, P, Konopnicki, D, Beauloye, C, Pasquet, A, Pierard, S, Vancraeynest, D, Vanoverschelde, J, Sinnaeve, F, Andrade, J, Rodrigues, A, Staszko, K, Dos Santos Monteiro, R, Shuha, D, Alcantara, M, Cravo, V, Fazzio, L, Felix, A, Iso, M, Musa, C, Siciliano, A, Filho, F, Braga, J, Silva, R, Vilela, F, Rodrigues, D, Silva, L, Morhy, S, Fischer, C, Vieira, M, Afonso, T, Abreu, J, Falcao, S, Moises, V, Gouvea, A, Joao, G, Mancuso, F, Silva, C, Souza, A, Abboud, C, de Mattos Barretto, R, Ramos, A, Arnoni, R, Assef, J, Togna, D, Le Bihan, D, Miglioli, L, Oliveira, A, Kroll, R, Cortez, D, Gelape, C, De Abreu Ferrari, T, Chan, K, Hay, K, Le, V, Page, M, Poulin, F, Sauve, C, Serri, K, Mercure, C, Beaudoin, J, Pibarot, P, Sebag, I, Rudski, L, Ricafort, G, Barsic, B, Krajinovic, V, Vargovic, M, Separovic-Hanzevacki, J, Lovric, D, Reskovic-Luksic, V, Vincelj, J, Jurinjak, S, Yiannikourides, V, Ioannides, M, Kyriakou, C, Pofaides, C, Masoura, V, Yiangou, K, Pudich, J, Linhart, A, Siranec, M, Marek, J, Blechova, K, Kamenik, M, Pelouch, R, Coufal, Z, Mikulica, M, Griva, M, Jancova, E, Mikulcova, M, Taborsky, M, Precek, J, Jecmenova, M, Latal, J, Widimsky, J, Butta, T, Machacek, S, Vancata, R, Spinar, J, Holicka, M, Long, F, Anzules, N, Carpio, A, Largacha, G, Penaherrera, E, Moreira, D, Mahfouz, E, Elsafty, E, Soliman, A, Zayed, Y, Aboulenein, J, Abdel-Hay, M, Almaghraby, A, Abdelnaby, M, Ahmed, M, Hammad, B, Saleh, Y, Zahran, H, Elgebaly, O, Saad, A, Ali, M, Zeid, A, Sharkawy, R, Meshaal, M, Al Kholy, A, Doss, R, Osama, D, Rizk, H, Elmogy, A, Mishriky, M, Assayag, P, Hatimi, S, Botelho-Nevers, S, Campisi, S, Fuzellier, J, Gagneux-Brunon, A, Pierrard, R, Tulane, C, Detoc, M, Mehalla, T, Boutoille, D, Al Habash, O, Asseray-Madani, N, Biron, C, Brochard, J, Caillon, J, Cueff, C, Le Tourneau, T, Lecompte, A, Lecomte, R, Lefebvre, M, Michel, M, Pattier, S, Delarue, S, Le Bras, M, Orain, J, Faucher, J, Aboyans, V, Beeharry, A, Durox, H, Lacoste, M, Mohty, D, David, A, Pradel, V, Sierra, V, Neykova, A, Bettayeb, B, Elkentaoui, S, Tzvetkov, B, Landry, G, Strady, C, Ainine, K, Baumard, S, Brasselet, C, Tassigny, C, Valente-Pires, V, Lefranc, M, Hoen, B, Lefevre, B, Curlier, E, Callier, C, Fourcade, N, Jobic, Y, Ansard, S, Le Berre, R, Le Roux, P, Le Ven, F, Pouliquen, M, Prat, G, Bouchart, F, Savoure, A, Alarcon, C, Chapuzet, C, Gueit, I, Tribouilloy, C, Bohbot, Y, Peugnet, F, Gun, M, Duval, X, Lescure, X, Ilic-Habensus, E, Sadoul, N, Chevalier, E, Goehringer, F, Huttin, O, Garcia, R, Le Marcis, V, Tattevin, P, Donal, E, Flecher, E, Revest, M, Hubert, S, Casalta, J, Gouriet, F, Arregle, F, Cammilleri, S, Tessonnier, L, Riberi, A, Chirouze, C, Bouiller, K, Brunel, A, Fournier, D, Hustache-Mathieu, L, Klopfenstein, T, Moreau, J, Lim, P, Oliver, L, Ternacle, J, Moussafeur, A, Chavanet, P, Piroth, L, Buisson, M, Mahy, S, Martins, C, Salmon-Rousseau, A, Gohier, S, Borgermann, J, Guckel, D, Horstkotte, D, Brockmeier, B, Winkelmann, E, Hagendorff, A, Grey, D, Nickenig, G, Schueler, R, Ozturk, C, Stohr, E, Hamm, C, Walther, T, Brandt, R, Fruhauf, A, Hartung, C, Hellner, C, Wild, C, Becker, M, Hamada, S, Kaestner, W, Stangl, K, Knebel, F, Baldenhofer, G, Brecht, A, Dreger, H, Isner, C, Pfafflin, F, Stegemann, M, Zahn, R, Fraiture, B, Kilkowski, C, Karcher, A, Klinger, S, Tolksdorf, H, Tousoulis, D, Aggeli, C, Sarri, G, Sideris, S, Venieri, E, Athanassopoulos, G, Tsiapras, D, Armenis, I, Koutsiari, A, Floros, G, Grassos, C, Dragasis, S, Rallidis, L, Varlamos, C, Michalis, L, Naka, K, Bechlioulis, A, Kotsia, A, Lakkas, L, Pappas, K, Papadopoulos, C, Kiokas, S, Lioni, A, Misailidou, S, Barbetseas, J, Bonou, M, Kapelios, C, Tomprou, I, Zerva, K, Manolis, A, Hamodraka, E, Athanasiou, D, Haralambidis, G, Poulimenos, L, Samaras, H, Nagy, A, Bartykowszki, A, Gara, E, Sengupta, S, Mungulmare, K, Kasliwal, R, Bansal, M, Bhan, A, Ranjan, S, Kyavar, M, Maleki, M, Bezanjani, F, Sadeghpour, A, Alizadehasl, A, Boudagh, S, Ghavidel, A, Moradnejad, P, Pasha, H, Ghadrdoost, B, Gilon, D, Strahilevitz, J, Israel, S, Wanounou, M, D'Agostino, C, Colonna, P, De Michele, L, Fumarola, F, Stante, M, Marchionni, N, Scheggi, V, Alterini, B, Del Pace, S, Stefano, P, Sparano, C, Badano, L, Muraru, D, Ruozi, N, Tenaglia, R, Limbruno, U, Cresti, A, Baratta, P, Solari, M, Giannattasio, C, Moreo, A, De Chiara, B, Montero, B, Musca, F, Orcese, C, Panzeri, F, Russo, C, Spano, F, Alfieri, O, De Bonis, M, Agricola, E, Busnardo, E, Carletti, S, Castiglioni, B, Chiappetta, S, Del Forno, B, Ferrara, D, Guffanti, M, Iaci, G, Lapenna, E, Nisi, T, Oltolini, C, Pajoro, U, Pasciuta, R, Ripa, M, Scarpellini, P, Din, C, Meneghin, R, Schiavi, D, Piscione, F, Citro, R, Benvenga, R, Greco, L, Prota, C, Radano, I, Soriente, L, Bellino, M, Di Vece, D, Santini, F, Salsano, A, Olivieri, G, Turrini, F, Messora, R, Tondi, S, Olaru, A, Agnoletto, V, Grassi, L, Leonardi, C, Sansoni, S, Del Ponte, S, Dato, G, Ohte, N, Kikuchi, S, Wakami, K, Aonuma, K, Seo, Y, Ishizu, T, Machino-Ohtsuka, T, Yamamoto, M, Iida, N, Nakajima, H, Nakagawa, Y, Izumi, C, Amano, M, Miyake, M, Takahashi, K, Shiojima, I, Miyasaka, Y, Maeba, H, Suwa, Y, Taniguchi, N, Tsujimoto, S, Kitai, T, Ota, M, Yuda, S, Sasaki, S, Hagiwara, N, Yamazaki, K, Ashihara, K, Arai, K, Saitou, C, Saitou, S, Suzuki, G, Shibata, Y, Watanabe, N, Nishino, S, Ashikaga, K, Kuriyama, N, Mahara, K, Abe, K, Fujimaki, H, Okubo, T, Shitan, H, Takanashi, S, Terada, M, Yamamoto, H, Sata, M, Kusunose, K, Saijo, Y, Seno, H, Yuichiro, O, Sakata, Y, Mizuno, H, Nakatani, S, Onishi, T, Sengoku, K, Sera, F, Park, S, Kyoung, K, Yeon, L, Hwang, J, Jin-Oh, C, Sang-Chol, L, Sung-A, C, Jang, S, Kang, D, Heo, R, Lee, S, Song, J, Jung, E, Plisiene, J, Dambrauskaite, A, Gruodyte, G, Jonkaitiene, R, Vaskelyte, J, Mizariene, V, Atkocaityte, J, Zvirblyte, R, Sow, R, Codreanu, A, De la Vega, E, Michaux, C, Staub, T, Jacobs-Orazi, L, Azzopardi, C, Xuereb, R, Piscopo, T, Borg, D, Casha, R, Farrugia, J, Fenech, M, Pllaha, E, Vella, C, Yamagata, K, Grib, L, Raevschi, E, Grejdieru, A, Balan, G, Cardaniuc, I, Cardaniuc, L, Corcea, V, Feodorovici, A, Gaina, V, Girbu, L, Jimbei, P, Kravcenco, D, Panfile, E, Prisacari, E, Samohvalov, E, Samohvalov, S, Sceglova, N, Benesco, I, Marian, V, Sumarga, N, Mirocevic, M, Bozovic, B, Bulatovic, N, Lakovic, P, Music, L, Roos-Hesselink, J, Budde, R, Gamela, T, Wahadat, A, Kamp, O, Meijers, T, Van Melle, J, Deursen, V, Crijns, H, Bekkers, S, Cheriex, E, Gilbers, M, Kietselaer, B, Knackstedt, C, Lorusso, R, Schalla, S, Streukens, S, Chamuleau, S, Cramer, M, Teske, A, Van der Spoel, T, Wind, A, Liesbek, O, Lokhorst, J, Van Heusden, H, Tanis, W, Van der Bilt, I, Vriend, J, De Lange-van Bruggen, H, Karijodikoro, E, van Dongen, E, Schoep, J, Stolk, V, Axler, O, Baumann, F, Lebras, S, Edvardsen, T, Offstad, J, Beitnes, J, Helle-Valle, T, Skulstad, H, Skardal, R, Qamar, N, Furnaz, S, Ahmed, B, Butt, M, Khanzada, M, Saghir, T, Wahid, A, Hryniewiecki, T, Szymanski, P, Marzec, K, Misztal-Ogonowska, M, Kosmala, W, Przewlocka-Kosmala, M, Rojek, A, Woznicka, K, Zachwyc, J, Lisowska, A, Kaminska, M, Kasprzak, J, Kowalczyk, E, Strzecka, D, Wejner-Mik, P, Trabulo, M, Freitas, P, Ranchordas, S, Rodrigues, G, Pinto, P, Queiros, C, Azevedo, J, Marques, L, Seabra, D, Branco, L, Cruz, M, Galrinho, A, Moreira, R, Rio, P, Timoteo, A, Selas, M, Cardim, N, Carmelo, V, Neves, B, Pereira, H, Cruz, I, Guerra, A, Marques, A, Pintassilgo, I, Tomescu, M, Trofenciuc, N, Andor, M, Bordejevic, A, Branea, H, Caruntu, F, Cirin, L, Citu, I, Cotoraci, C, Darabantiu, D, Farcas, R, Marincu, I, Mavrea, A, Onel, M, Parvanescu, T, Pop, D, Pop-Moldovan, A, Puticiu, M, Velcean, L, Ionac, A, Cozma, D, Mornos, C, Goanta, F, Popescu, I, Beyer, R, Mada, R, Rancea, R, Rosianu, H, Tomoaia, R, Stanescu, C, Kobalava, Z, Karaulova, J, Kotova, E, Milto, A, Pisaryuk, A, Povalyaev, N, Sorokina, M, Alrahimi, J, Elshiekh, A, Jamiel, A, Ahmed, A, Al-Mallah, M, Attia, N, Putnikovic, B, Neskovic, A, Dimic, A, Ivanovic, B, Matic, S, Trifunovic, D, Petrovic, J, Kosevic, D, Dabic, P, Milojevic, P, Petrovic, I, Stojanovic, I, Kovacevic, M, Redzek, A, Stefanovic, M, Susak, S, Velicki, L, Vulin, A, Yeo, T, Poh, K, Vilacosta, I, El-Nasser, M, Ferrera, C, Olmos, C, Iglesias, F, Blanco-Gonzalez, E, Amaro, M, Germinas, A, Lopez-Rodriguez, E, Adan, J, Pazos-Lopez, P, Loureiro, M, Perez, M, Raposeiras-Roubin, S, Yas, S, Suarez-Varela, M, Vidal, F, Garcia-Dorado, D, Sambola, A, Fernandez-Hidalgo, N, Gonzalez-Alujas, T, Lozano, J, Maisterra, O, Pizzi, N, Rios, R, Tornos, P, Bayes-Genis, A, Botet, L, Vallejo, N, Berastegui, E, Llibre, C, Mateu, L, Nunez, R, Quesada, D, Portell, D, Vinas, J, Bertran, X, Tarradellas, R, Ricon, P, de Llano, C, Arnau, M, Bel, A, Blanes, M, Osa, A, Anguita, M, Carrasco, F, Castillo, J, Zamorano, J, Mur, J, Alvaro, M, Fernandez-Golfin, C, Monteagudo, J, Elorza, E, Alvarez, M, Balbin, J, Arminanzas, C, de las Revillas, F, Garcia, A, Belaustegui, M, Sampedro, M, Cuadra, M, Gutierrez-Diez, J, Zarauza, J, Cuello, L, Rico, C, Rodriguez-Alvarez, R, Goikoetxea, J, Montejo, M, Miro, J, Almela, M, Ambrosioni, J, Falces, C, Fuster, D, Garcia-de-la-Maria, C, Hernandez-Meneses, M, Llopis, J, Marco, F, Moreno, A, Quintana, E, Sandoval, E, Tellez, A, Tolosana, J, Vidal, B, Ruiz-Zamora, I, Ruiz, A, Girgas, E, Garcia-Pardo, G, Marzo, M, Oviedo, A, Jimenez, A, Abid, L, Hammami, R, Kammoun, S, Mourali, M, Zghal, F, Hlima, M, Boudiche, S, Ouali, S, Zakhama, L, Antit, S, Slama, I, Gulel, O, Sahin, M, Sade, L, Karacaglar, E, Kucukoglu, S, Cetinarslan, O, Sinan, U, Canpolat, U, Atas, H, Dervishova, R, Ileri, C, Zaky, H, Alhashmi, J, Baslib, F, Tahir, J, Zarger, P, Woldman, S, Menezes, L, Primus, C, Uppal, R, Bvekerwa, I, Chandrasekaran, B, Kopanska, A, Prendergast, B, Cannata, S, Chambers, J, Hancock, J, Klein, J, Rajani, R, Ursi, M, Dworakowski, R, Fife, A, Breeze, J, Browne-Morgan, M, Gunning, M, Streather, S, Asch, F, Zemedkun, M, Alyavi, B, Uzokov, J, Pazdernik M., Iung B., Mutlu B., Alla F., Riezebos R., Kong W., Nunes M. C. P., Pierard L., Srdanovic I., Yamada H., De Martino A., Miglioranza M. H., Magne J., Piper C., Laroche C., Maggioni A. P., Lancellotti P., Habib G., Selton-Suty C., Ronderos R., Avegliano G., Oses P. F., Filipini E., Granada I., Iribarren A., Mahia M., Nacinovich F., Ressi S., Obregon R., Bangher M., Dho J., Cartasegna L., Plastino M. L., Novas V., Shigel C., Reyes G., De Santos M., Gastaldello N., Fernandez M. G., Potito M., Streitenberger G., Velazco P., Casabe J. H., Cortes C., Guevara E., Salmo F., Seijo M., Weidinger F., Heger M., Brooks R., Stollberger C., Ho C. -Y., Perschy L., Puskas L., Goliasch G., Binder C., Rosenhek R., Schneider M., Winter M. -P., Hoffer E., Melissopoulou M., Lecoq E., Legrand D., Jacquet S., Massoz M., Dulgheru R., Marchetta S., D'Emal C., Oury C., Cosyns B., Droogmans S., Kerkhove D., Motoc A., Plein D., Roosens B., Soens L., Weytjens C., Lemoine I., Rodrigus I., Paelinck B., Amsel B., Unger P., Konopnicki D., Beauloye C., Pasquet A., Pierard S., Vancraeynest D., Vanoverschelde J. L., Sinnaeve F., Andrade J. L., Rodrigues A. C. T., Staszko K., Dos Santos Monteiro R., Shuha D. L., Alcantara M., Cravo V., Fazzio L., Felix A., Iso M., Musa C., Siciliano A. P., Filho F. V., Braga J., Rodrigues A., Silva R., Vilela F., Rodrigues D., Silva L., Morhy S., Fischer C., Vieira M., Afonso T., Abreu J., Falcao S. N., Moises V., Gouvea A., Joao G., Mancuso F., Silva C., Souza A. C., Abboud C. S., de Mattos Barretto R. B., Ramos A., Arnoni R., Assef J. E., Togna D. J. D., Le Bihan D., Miglioli L., Oliveira A. P. R., Kroll R. T. M., Cortez D., Gelape C. L., De Abreu Ferrari T. C., Chan K. -L., Hay K., Le V., Page M., Poulin F., Sauve C., Serri K., Mercure C., Beaudoin J., Pibarot P., Sebag I., Rudski L., Ricafort G., Barsic B., Krajinovic V., Vargovic M., Separovic-Hanzevacki J., Lovric D., Reskovic-Luksic V., Vincelj J., Jurinjak S. J., Yiannikourides V., Ioannides M., Kyriakou C., Pofaides C., Masoura V., Yiangou K., Pudich J., Linhart A., Siranec M., Marek J., Blechova K., Kamenik M., Pelouch R., Coufal Z., Mikulica M., Griva M., Jancova E., Mikulcova M., Taborsky M., Precek J., Jecmenova M., Latal J., Widimsky J., Butta T., Machacek S., Vancata R., Spinar J., Holicka M., Long F. P. C., Anzules N., Carpio A. B., Largacha G., Penaherrera E., Moreira D., Mahfouz E., Elsafty E., Soliman A., Zayed Y., Aboulenein J., Abdel-Hay M., Almaghraby A., Abdelnaby M., Ahmed M., Hammad B., Saleh Y., Zahran H., Elgebaly O., Saad A., Ali M., Zeid A., Sharkawy R. E., Meshaal M., Al Kholy A., Doss R., Osama D., Rizk H., Elmogy A., Mishriky M., Assayag P., Hatimi S. E., Botelho-Nevers S. -E., Campisi S., Fuzellier J. -F., Gagneux-Brunon A., Pierrard R., Tulane C., Detoc M., Mehalla T., Boutoille D., Al Habash O., Asseray-Madani N., Biron C., Brochard J., Caillon J., Cueff C., Le Tourneau T., Lecompte A. S., Lecomte R., Lefebvre M., Michel M. M. M., Pattier S., Delarue S., Le Bras M., Orain J., Faucher J. -F., Aboyans V., Beeharry A., Durox H., Lacoste M., Mohty D., David A., Pradel V., Sierra V., Neykova A., Bettayeb B., Elkentaoui S., Tzvetkov B., Landry G., Strady C., Ainine K., Baumard S., Brasselet C., Tassigny C., Valente-Pires V., Lefranc M., Hoen B., Lefevre B., Curlier E., Callier C., Fourcade N., Jobic Y., Ansard S., Le Berre R., Le Roux P., Le Ven F., Pouliquen M. -C., Prat G., Bouchart F., Savoure A., Alarcon C., Chapuzet C., Gueit I., Tribouilloy C., Bohbot Y., Peugnet F., Gun M., Duval X., Lescure X., Ilic-Habensus E., Sadoul N., Chevalier E., Goehringer F., Huttin O., Garcia R., Le Marcis V., Tattevin P., Donal E., Flecher E., Revest M., Hubert S., Casalta J. -P., Gouriet F., Arregle F., Cammilleri S., Tessonnier L., Riberi A., Chirouze C., Bouiller K., Brunel A. -S., Fournier D., Hustache-Mathieu L., Klopfenstein T., Moreau J., Lim P., Oliver L., Ternacle J., Moussafeur A., Chavanet P., Piroth L., Buisson M., Mahy S., Martins C., Salmon-Rousseau A., Gohier S., Borgermann J., Guckel D., Horstkotte D., Brockmeier B., Winkelmann E., Hagendorff A., Grey D., Nickenig G., Schueler R., Ozturk C., Stohr E., Hamm C., Walther T., Brandt R., Fruhauf A. -C., Hartung C. T., Hellner C., Wild C., Becker M., Hamada S., Kaestner W., Stangl K., Knebel F., Baldenhofer G., Brecht A., Dreger H., Isner C., Pfafflin F., Stegemann M., Zahn R., Fraiture B., Kilkowski C., Karcher A. -K., Klinger S., Tolksdorf H., Tousoulis D., Aggeli C., Sarri G., Sideris S., Venieri E., Athanassopoulos G., Tsiapras D., Armenis I., Koutsiari A., Floros G., Grassos C., Dragasis S., Rallidis L., Varlamos C., Michalis L., Naka K., Bechlioulis A., Kotsia A., Lakkas L., Pappas K., Papadopoulos C., Kiokas S., Lioni A., Misailidou S., Barbetseas J., Bonou M., Kapelios C., Tomprou I., Zerva K., Manolis A., Hamodraka E., Athanasiou D., Haralambidis G., Poulimenos L., Samaras H., Nagy A., Bartykowszki A., Gara E., Sengupta S., Mungulmare K., Kasliwal R., Bansal M., Bhan A., Ranjan S., Kyavar M., Maleki M., Bezanjani F. N., Sadeghpour A., Alizadehasl A., Boudagh S., Ghavidel A., Moradnejad P., Pasha H. R., Ghadrdoost B., Gilon D., Strahilevitz J., Israel S., Wanounou M., d'Agostino C., Colonna P., De Michele L., Fumarola F., Stante M., Marchionni N., Scheggi V., Alterini B., Del Pace S., Stefano P., Sparano C., Badano L., Muraru D., Ruozi N., Tenaglia R., Limbruno U., Cresti A., Baratta P., Solari M., Giannattasio C., Moreo A., De Chiara B., Montero B. L., Musca F., Orcese C. A., Panzeri F., Russo C. F., Spano F., Alfieri O., De Bonis M., Agricola E., Busnardo E., Carletti S., Castiglioni B., Chiappetta S., Del Forno B., Ferrara D., Guffanti M., Iaci G., Lapenna E., Nisi T., Oltolini C., Pajoro U., Pasciuta R., Ripa M., Scarpellini P., Din C. T., Meneghin R., Schiavi D., Piscione F., Citro R., Benvenga R. M., Greco L., Prota C., Radano I., Soriente L., Bellino M., Di Vece D., Santini F., Salsano A., Olivieri G. M., Turrini F., Messora R., Tondi S., Olaru A., Agnoletto V., Grassi L., Leonardi C., Sansoni S., Del Ponte S., Dato G. M. A., Ohte N., Kikuchi S., Wakami K., Aonuma K., Seo Y., Ishizu T., Machino-Ohtsuka T., Yamamoto M., Iida N., Nakajima H., Nakagawa Y., Izumi C., Amano M., Miyake M., Takahashi K., Shiojima I., Miyasaka Y., Maeba H., Suwa Y., Taniguchi N., Tsujimoto S., Kitai T., Ota M., Yuda S., Sasaki S., Hagiwara N., Yamazaki K., Ashihara K., Arai K., Saitou C., Saitou S., Suzuki G., Shibata Y., Watanabe N., Nishino S., Ashikaga K., Kuriyama N., Mahara K., Abe K., Fujimaki H., Okubo T., Shitan H., Takanashi S., Terada M., Yamamoto H., Sata M., Kusunose K., Saijo Y., Seno H., Yuichiro O., Sakata Y., Mizuno H., Nakatani S., Onishi T., Sengoku K., Sera F., Park S. W., Kyoung K. E., Yeon L. G., Hwang J. -W., Jin-Oh C., Park S. -J., Sang-Chol L., Sung-A C., Jang S. Y., Kang D. -H., Heo R., Lee S., Song J. -M., Jung E., Plisiene J., Dambrauskaite A., Gruodyte G., Jonkaitiene R., Vaskelyte J., Mizariene V., Atkocaityte J., Zvirblyte R., Sow R., Codreanu A., De la Vega E. C. L., Michaux C., Staub T., Jacobs-Orazi L., Azzopardi C. M., Xuereb R. G., Piscopo T., Borg D., Casha R., Farrugia J., Fenech M., Pllaha E., Vella C., Yamagata K., Grib L., Raevschi E., Grejdieru A., Balan G., Cardaniuc I., Cardaniuc L., Corcea V., Feodorovici A., Gaina V., Girbu L., Jimbei P., Kravcenco D., Panfile E., Prisacari E., Samohvalov E., Samohvalov S., Sceglova N., Benesco I., Marian V., Sumarga N., Mirocevic M., Bozovic B., Bulatovic N., Lakovic P., Music L., Roos-Hesselink J., Budde R., Gamela T., Wahadat A., Kamp O., Meijers T., Van Melle J. P., Deursen V. M., Crijns H., Bekkers S., Cheriex E., Gilbers M., Kietselaer B., Knackstedt C., Lorusso R., Schalla S., Streukens S., Chamuleau S., Cramer M. -J., Teske A., Van der Spoel T., Wind A., Liesbek O., Lokhorst J., Van Heusden H., Tanis W., Van der Bilt I., Vriend J., De Lange-van Bruggen H., Karijodikoro E., van Dongen E., Schoep J., Stolk V., Axler O., Baumann F., Lebras S., Edvardsen T., Offstad J. T., Beitnes J. O., Helle-Valle T., Skulstad H., Skardal R., Qamar N., Furnaz S., Ahmed B., Butt M. H., Khanzada M. F., Saghir T., Wahid A., Hryniewiecki T., Szymanski P., Marzec K., Misztal-Ogonowska M., Kosmala W., Przewlocka-Kosmala M., Rojek A., Woznicka K., Zachwyc J., Lisowska A., Kaminska M., Kasprzak J., Kowalczyk E., Strzecka D. F., Wejner-Mik P., Trabulo M., Freitas P., Ranchordas S., Rodrigues G., Pinto P., Queiros C., Azevedo J., Marques L., Seabra D., Branco L., Cruz M., Galrinho A., Moreira R., Rio P., Timoteo A. T., Selas M., Cardim N. M., Carmelo V., Neves B. D., Pereira H., Cruz I., Guerra A., Marques A., Pintassilgo I., Tomescu M. C., Trofenciuc N. -M., Andor M., Bordejevic A., Branea H. S., Caruntu F., Cirin L., Citu I. M., Cotoraci C. A., Darabantiu D., Farcas R., Marincu I., Mavrea A., Onel M. F., Parvanescu T., Pop D., Pop-Moldovan A. L., Puticiu M. I., Velcean L. A., Ionac A., Cozma D., Mornos C., Goanta F., Popescu I., Beyer R., Mada R., Rancea R., Rosianu H., Tomoaia R., Stanescu C., Kobalava Z., Karaulova J., Kotova E., Milto A., Pisaryuk A., Povalyaev N., Sorokina M., Alrahimi J., Elshiekh A., Jamiel A., Ahmed A., Al-Mallah M., Attia N., Putnikovic B., Neskovic A., Dimic A., Ivanovic B., Matic S., Trifunovic D., Petrovic J., Kosevic D., Dabic P., Milojevic P., Petrovic I., Stojanovic I., Kovacevic M., Redzek A., Stefanovic M., Susak S., Velicki L., Vulin A., Yeo T. C., Kong W. K. F., Poh K. K., Vilacosta I., El-Nasser M. A., Ferrera C., Olmos C., Iglesias F. C., Blanco-Gonzalez E., Amaro M. B., Germinas A. N., Lopez-Rodriguez E., Adan J. L., Pazos-Lopez P., Loureiro M. P., Perez M. T., Raposeiras-Roubin S., Yas S. R., Suarez-Varela M. -M., Vidal F. V., Garcia-Dorado D., Sambola A., Fernandez-Hidalgo N., Gonzalez-Alujas T., Lozano J., Maisterra O., Pizzi N., Rios R., Tornos P., Bayes-Genis A., Botet L. P., Vallejo N., Berastegui E., Llibre C., Mateu L., Nunez R., Quesada D., Portell D. B., Vinas J. A., Bertran X. A., Tarradellas R. B., Ricon P. L. -O., de Llano C. T., Arnau M. A., Bel A., Blanes M., Osa A., Anguita M., Carrasco F., Castillo J., Zamorano J. L., Mur J. L. M., Alvaro M., Fernandez-Golfin C., Monteagudo J. M., Elorza E. N., Alvarez M. C. F., Balbin J. A., Arminanzas C., de las Revillas F. A., Garcia A. A., Belaustegui M. C., Sampedro M. F., Cuadra M. G., Gutierrez-Diez J. F., Zarauza J., Cuello L. G., Rico C. G., Rodriguez-Alvarez R., Goikoetxea J., Montejo M., Miro J., Almela M., Ambrosioni J., Falces C., Fuster D., Garcia-de-la-Maria C., Hernandez-Meneses M., Llopis J., Marco F., Moreno A., Quintana E., Sandoval E., Tellez A., Tolosana J. M., Vidal B., Ruiz-Zamora I., Ruiz A. B., Girgas E. S., Garcia-Pardo G., Marzo M. G., Oviedo A. R., Jimenez A. V., Abid L., Hammami R., Kammoun S., Mourali M. S., Zghal F. M., Hlima M. B., Boudiche S., Ouali S., Zakhama L., Antit S., Slama I., Gulel O., Sahin M., Sade L. E., Karacaglar E., Kucukoglu S., Cetinarslan O., Sinan U. Y., Canpolat U., Atas H., Dervishova R., Ileri C., Zaky H., Alhashmi J., Baslib F., Tahir J., Zarger P., Woldman S., Menezes L., Primus C., Uppal R., Bvekerwa I., Chandrasekaran B., Kopanska A., Prendergast B., Cannata S., Chambers J., Hancock J., Klein J., Rajani R., Ursi M. P., Dworakowski R., Fife A., Breeze J., Browne-Morgan M., Gunning M., Streather S., Asch F., Zemedkun M., Alyavi B., Uzokov J., Pazdernik M., Pazdernik, M, Iung, B, Mutlu, B, Alla, F, Riezebos, R, Kong, W, Nunes, M, Pierard, L, Srdanovic, I, Yamada, H, De Martino, A, Miglioranza, M, Magne, J, Piper, C, Laroche, C, Maggioni, A, Lancellotti, P, Habib, G, Selton-Suty, C, Ronderos, R, Avegliano, G, Oses, P, Filipini, E, Granada, I, Iribarren, A, Mahia, M, Nacinovich, F, Ressi, S, Obregon, R, Bangher, M, Dho, J, Cartasegna, L, Plastino, M, Novas, V, Shigel, C, Reyes, G, De Santos, M, Gastaldello, N, Fernandez, M, Potito, M, Streitenberger, G, Velazco, P, Casabe, J, Cortes, C, Guevara, E, Salmo, F, Seijo, M, Weidinger, F, Heger, M, Brooks, R, Stollberger, C, Ho, C, Perschy, L, Puskas, L, Goliasch, G, Binder, C, Rosenhek, R, Schneider, M, Winter, M, Hoffer, E, Melissopoulou, M, Lecoq, E, Legrand, D, Jacquet, S, Massoz, M, Dulgheru, R, Marchetta, S, D'Emal, C, Oury, C, Cosyns, B, Droogmans, S, Kerkhove, D, Motoc, A, Plein, D, Roosens, B, Soens, L, Weytjens, C, Lemoine, I, Rodrigus, I, Paelinck, B, Amsel, B, Unger, P, Konopnicki, D, Beauloye, C, Pasquet, A, Pierard, S, Vancraeynest, D, Vanoverschelde, J, Sinnaeve, F, Andrade, J, Rodrigues, A, Staszko, K, Dos Santos Monteiro, R, Shuha, D, Alcantara, M, Cravo, V, Fazzio, L, Felix, A, Iso, M, Musa, C, Siciliano, A, Filho, F, Braga, J, Silva, R, Vilela, F, Rodrigues, D, Silva, L, Morhy, S, Fischer, C, Vieira, M, Afonso, T, Abreu, J, Falcao, S, Moises, V, Gouvea, A, Joao, G, Mancuso, F, Silva, C, Souza, A, Abboud, C, de Mattos Barretto, R, Ramos, A, Arnoni, R, Assef, J, Togna, D, Le Bihan, D, Miglioli, L, Oliveira, A, Kroll, R, Cortez, D, Gelape, C, De Abreu Ferrari, T, Chan, K, Hay, K, Le, V, Page, M, Poulin, F, Sauve, C, Serri, K, Mercure, C, Beaudoin, J, Pibarot, P, Sebag, I, Rudski, L, Ricafort, G, Barsic, B, Krajinovic, V, Vargovic, M, Separovic-Hanzevacki, J, Lovric, D, Reskovic-Luksic, V, Vincelj, J, Jurinjak, S, Yiannikourides, V, Ioannides, M, Kyriakou, C, Pofaides, C, Masoura, V, Yiangou, K, Pudich, J, Linhart, A, Siranec, M, Marek, J, Blechova, K, Kamenik, M, Pelouch, R, Coufal, Z, Mikulica, M, Griva, M, Jancova, E, Mikulcova, M, Taborsky, M, Precek, J, Jecmenova, M, Latal, J, Widimsky, J, Butta, T, Machacek, S, Vancata, R, Spinar, J, Holicka, M, Long, F, Anzules, N, Carpio, A, Largacha, G, Penaherrera, E, Moreira, D, Mahfouz, E, Elsafty, E, Soliman, A, Zayed, Y, Aboulenein, J, Abdel-Hay, M, Almaghraby, A, Abdelnaby, M, Ahmed, M, Hammad, B, Saleh, Y, Zahran, H, Elgebaly, O, Saad, A, Ali, M, Zeid, A, Sharkawy, R, Meshaal, M, Al Kholy, A, Doss, R, Osama, D, Rizk, H, Elmogy, A, Mishriky, M, Assayag, P, Hatimi, S, Botelho-Nevers, S, Campisi, S, Fuzellier, J, Gagneux-Brunon, A, Pierrard, R, Tulane, C, Detoc, M, Mehalla, T, Boutoille, D, Al Habash, O, Asseray-Madani, N, Biron, C, Brochard, J, Caillon, J, Cueff, C, Le Tourneau, T, Lecompte, A, Lecomte, R, Lefebvre, M, Michel, M, Pattier, S, 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Ranjan, S, Kyavar, M, Maleki, M, Bezanjani, F, Sadeghpour, A, Alizadehasl, A, Boudagh, S, Ghavidel, A, Moradnejad, P, Pasha, H, Ghadrdoost, B, Gilon, D, Strahilevitz, J, Israel, S, Wanounou, M, D'Agostino, C, Colonna, P, De Michele, L, Fumarola, F, Stante, M, Marchionni, N, Scheggi, V, Alterini, B, Del Pace, S, Stefano, P, Sparano, C, Badano, L, Muraru, D, Ruozi, N, Tenaglia, R, Limbruno, U, Cresti, A, Baratta, P, Solari, M, Giannattasio, C, Moreo, A, De Chiara, B, Montero, B, Musca, F, Orcese, C, Panzeri, F, Russo, C, Spano, F, Alfieri, O, De Bonis, M, Agricola, E, Busnardo, E, Carletti, S, Castiglioni, B, Chiappetta, S, Del Forno, B, Ferrara, D, Guffanti, M, Iaci, G, Lapenna, E, Nisi, T, Oltolini, C, Pajoro, U, Pasciuta, R, Ripa, M, Scarpellini, P, Din, C, Meneghin, R, Schiavi, D, Piscione, F, Citro, R, Benvenga, R, Greco, L, Prota, C, Radano, I, Soriente, L, Bellino, M, Di Vece, D, Santini, F, Salsano, A, Olivieri, G, Turrini, F, Messora, R, Tondi, S, Olaru, A, Agnoletto, V, Grassi, 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Furnaz, S, Ahmed, B, Butt, M, Khanzada, M, Saghir, T, Wahid, A, Hryniewiecki, T, Szymanski, P, Marzec, K, Misztal-Ogonowska, M, Kosmala, W, Przewlocka-Kosmala, M, Rojek, A, Woznicka, K, Zachwyc, J, Lisowska, A, Kaminska, M, Kasprzak, J, Kowalczyk, E, Strzecka, D, Wejner-Mik, P, Trabulo, M, Freitas, P, Ranchordas, S, Rodrigues, G, Pinto, P, Queiros, C, Azevedo, J, Marques, L, Seabra, D, Branco, L, Cruz, M, Galrinho, A, Moreira, R, Rio, P, Timoteo, A, Selas, M, Cardim, N, Carmelo, V, Neves, B, Pereira, H, Cruz, I, Guerra, A, Marques, A, Pintassilgo, I, Tomescu, M, Trofenciuc, N, Andor, M, Bordejevic, A, Branea, H, Caruntu, F, Cirin, L, Citu, I, Cotoraci, C, Darabantiu, D, Farcas, R, Marincu, I, Mavrea, A, Onel, M, Parvanescu, T, Pop, D, Pop-Moldovan, A, Puticiu, M, Velcean, L, Ionac, A, Cozma, D, Mornos, C, Goanta, F, Popescu, I, Beyer, R, Mada, R, Rancea, R, Rosianu, H, Tomoaia, R, Stanescu, C, Kobalava, Z, Karaulova, J, Kotova, E, Milto, A, Pisaryuk, A, Povalyaev, N, Sorokina, M, 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J, Browne-Morgan, M, Gunning, M, Streather, S, Asch, F, Zemedkun, M, Alyavi, B, Uzokov, J, Pazdernik M., Iung B., Mutlu B., Alla F., Riezebos R., Kong W., Nunes M. C. P., Pierard L., Srdanovic I., Yamada H., De Martino A., Miglioranza M. H., Magne J., Piper C., Laroche C., Maggioni A. P., Lancellotti P., Habib G., Selton-Suty C., Ronderos R., Avegliano G., Oses P. F., Filipini E., Granada I., Iribarren A., Mahia M., Nacinovich F., Ressi S., Obregon R., Bangher M., Dho J., Cartasegna L., Plastino M. L., Novas V., Shigel C., Reyes G., De Santos M., Gastaldello N., Fernandez M. G., Potito M., Streitenberger G., Velazco P., Casabe J. H., Cortes C., Guevara E., Salmo F., Seijo M., Weidinger F., Heger M., Brooks R., Stollberger C., Ho C. -Y., Perschy L., Puskas L., Goliasch G., Binder C., Rosenhek R., Schneider M., Winter M. -P., Hoffer E., Melissopoulou M., Lecoq E., Legrand D., Jacquet S., Massoz M., Dulgheru R., Marchetta S., D'Emal C., Oury C., Cosyns B., Droogmans S., Kerkhove D., Motoc A., Plein D., Roosens B., Soens L., Weytjens C., Lemoine I., Rodrigus I., Paelinck B., Amsel B., Unger P., Konopnicki D., Beauloye C., Pasquet A., Pierard S., Vancraeynest D., Vanoverschelde J. L., Sinnaeve F., Andrade J. L., Rodrigues A. C. T., Staszko K., Dos Santos Monteiro R., Shuha D. L., Alcantara M., Cravo V., Fazzio L., Felix A., Iso M., Musa C., Siciliano A. P., Filho F. V., Braga J., Rodrigues A., Silva R., Vilela F., Rodrigues D., Silva L., Morhy S., Fischer C., Vieira M., Afonso T., Abreu J., Falcao S. N., Moises V., Gouvea A., Joao G., Mancuso F., Silva C., Souza A. C., Abboud C. S., de Mattos Barretto R. B., Ramos A., Arnoni R., Assef J. E., Togna D. J. D., Le Bihan D., Miglioli L., Oliveira A. P. R., Kroll R. T. M., Cortez D., Gelape C. L., De Abreu Ferrari T. C., Chan K. -L., Hay K., Le V., Page M., Poulin F., Sauve C., Serri K., Mercure C., Beaudoin J., Pibarot P., Sebag I., Rudski L., Ricafort G., Barsic B., Krajinovic V., Vargovic M., Separovic-Hanzevacki J., Lovric D., Reskovic-Luksic V., Vincelj J., Jurinjak S. J., Yiannikourides V., Ioannides M., Kyriakou C., Pofaides C., Masoura V., Yiangou K., Pudich J., Linhart A., Siranec M., Marek J., Blechova K., Kamenik M., Pelouch R., Coufal Z., Mikulica M., Griva M., Jancova E., Mikulcova M., Taborsky M., Precek J., Jecmenova M., Latal J., Widimsky J., Butta T., Machacek S., Vancata R., Spinar J., Holicka M., Long F. P. C., Anzules N., Carpio A. B., Largacha G., Penaherrera E., Moreira D., Mahfouz E., Elsafty E., Soliman A., Zayed Y., Aboulenein J., Abdel-Hay M., Almaghraby A., Abdelnaby M., Ahmed M., Hammad B., Saleh Y., Zahran H., Elgebaly O., Saad A., Ali M., Zeid A., Sharkawy R. E., Meshaal M., Al Kholy A., Doss R., Osama D., Rizk H., Elmogy A., Mishriky M., Assayag P., Hatimi S. E., Botelho-Nevers S. -E., Campisi S., Fuzellier J. -F., Gagneux-Brunon A., Pierrard R., Tulane C., Detoc M., Mehalla T., Boutoille D., Al Habash O., Asseray-Madani N., Biron C., Brochard J., Caillon J., Cueff C., Le Tourneau T., Lecompte A. S., Lecomte R., Lefebvre M., Michel M. M. M., Pattier S., Delarue S., Le Bras M., Orain J., Faucher J. -F., Aboyans V., Beeharry A., Durox H., Lacoste M., Mohty D., David A., Pradel V., Sierra V., Neykova A., Bettayeb B., Elkentaoui S., Tzvetkov B., Landry G., Strady C., Ainine K., Baumard S., Brasselet C., Tassigny C., Valente-Pires V., Lefranc M., Hoen B., Lefevre B., Curlier E., Callier C., Fourcade N., Jobic Y., Ansard S., Le Berre R., Le Roux P., Le Ven F., Pouliquen M. -C., Prat G., Bouchart F., Savoure A., Alarcon C., Chapuzet C., Gueit I., Tribouilloy C., Bohbot Y., Peugnet F., Gun M., Duval X., Lescure X., Ilic-Habensus E., Sadoul N., Chevalier E., Goehringer F., Huttin O., Garcia R., Le Marcis V., Tattevin P., Donal E., Flecher E., Revest M., Hubert S., Casalta J. -P., Gouriet F., Arregle F., Cammilleri S., Tessonnier L., Riberi A., Chirouze C., Bouiller K., Brunel A. -S., Fournier D., Hustache-Mathieu L., Klopfenstein T., Moreau J., Lim P., Oliver L., Ternacle J., Moussafeur A., Chavanet P., Piroth L., Buisson M., Mahy S., Martins C., Salmon-Rousseau A., Gohier S., Borgermann J., Guckel D., Horstkotte D., Brockmeier B., Winkelmann E., Hagendorff A., Grey D., Nickenig G., Schueler R., Ozturk C., Stohr E., Hamm C., Walther T., Brandt R., Fruhauf A. -C., Hartung C. T., Hellner C., Wild C., Becker M., Hamada S., Kaestner W., Stangl K., Knebel F., Baldenhofer G., Brecht A., Dreger H., Isner C., Pfafflin F., Stegemann M., Zahn R., Fraiture B., Kilkowski C., Karcher A. -K., Klinger S., Tolksdorf H., Tousoulis D., Aggeli C., Sarri G., Sideris S., Venieri E., Athanassopoulos G., Tsiapras D., Armenis I., Koutsiari A., Floros G., Grassos C., Dragasis S., Rallidis L., Varlamos C., Michalis L., Naka K., Bechlioulis A., Kotsia A., Lakkas L., Pappas K., Papadopoulos C., Kiokas S., Lioni A., Misailidou S., Barbetseas J., Bonou M., Kapelios C., Tomprou I., Zerva K., Manolis A., Hamodraka E., Athanasiou D., Haralambidis G., Poulimenos L., Samaras H., Nagy A., Bartykowszki A., Gara E., Sengupta S., Mungulmare K., Kasliwal R., Bansal M., Bhan A., Ranjan S., Kyavar M., Maleki M., Bezanjani F. N., Sadeghpour A., Alizadehasl A., Boudagh S., Ghavidel A., Moradnejad P., Pasha H. R., Ghadrdoost B., Gilon D., Strahilevitz J., Israel S., Wanounou M., d'Agostino C., Colonna P., De Michele L., Fumarola F., Stante M., Marchionni N., Scheggi V., Alterini B., Del Pace S., Stefano P., Sparano C., Badano L., Muraru D., Ruozi N., Tenaglia R., Limbruno U., Cresti A., Baratta P., Solari M., Giannattasio C., Moreo A., De Chiara B., Montero B. L., Musca F., Orcese C. A., Panzeri F., Russo C. F., Spano F., Alfieri O., De Bonis M., Agricola E., Busnardo E., Carletti S., Castiglioni B., Chiappetta S., Del Forno B., Ferrara D., Guffanti M., Iaci G., Lapenna E., Nisi T., Oltolini C., Pajoro U., Pasciuta R., Ripa M., Scarpellini P., Din C. T., Meneghin R., Schiavi D., Piscione F., Citro R., Benvenga R. M., Greco L., Prota C., Radano I., Soriente L., Bellino M., Di Vece D., Santini F., Salsano A., Olivieri G. M., Turrini F., Messora R., Tondi S., Olaru A., Agnoletto V., Grassi L., Leonardi C., Sansoni S., Del Ponte S., Dato G. M. A., Ohte N., Kikuchi S., Wakami K., Aonuma K., Seo Y., Ishizu T., Machino-Ohtsuka T., Yamamoto M., Iida N., Nakajima H., Nakagawa Y., Izumi C., Amano M., Miyake M., Takahashi K., Shiojima I., Miyasaka Y., Maeba H., Suwa Y., Taniguchi N., Tsujimoto S., Kitai T., Ota M., Yuda S., Sasaki S., Hagiwara N., Yamazaki K., Ashihara K., Arai K., Saitou C., Saitou S., Suzuki G., Shibata Y., Watanabe N., Nishino S., Ashikaga K., Kuriyama N., Mahara K., Abe K., Fujimaki H., Okubo T., Shitan H., Takanashi S., Terada M., Yamamoto H., Sata M., Kusunose K., Saijo Y., Seno H., Yuichiro O., Sakata Y., Mizuno H., Nakatani S., Onishi T., Sengoku K., Sera F., Park S. W., Kyoung K. E., Yeon L. G., Hwang J. -W., Jin-Oh C., Park S. -J., Sang-Chol L., Sung-A C., Jang S. Y., Kang D. -H., Heo R., Lee S., Song J. -M., Jung E., Plisiene J., Dambrauskaite A., Gruodyte G., Jonkaitiene R., Vaskelyte J., Mizariene V., Atkocaityte J., Zvirblyte R., Sow R., Codreanu A., De la Vega E. C. L., Michaux C., Staub T., Jacobs-Orazi L., Azzopardi C. M., Xuereb R. G., Piscopo T., Borg D., Casha R., Farrugia J., Fenech M., Pllaha E., Vella C., Yamagata K., Grib L., Raevschi E., Grejdieru A., Balan G., Cardaniuc I., Cardaniuc L., Corcea V., Feodorovici A., Gaina V., Girbu L., Jimbei P., Kravcenco D., Panfile E., Prisacari E., Samohvalov E., Samohvalov S., Sceglova N., Benesco I., Marian V., Sumarga N., Mirocevic M., Bozovic B., Bulatovic N., Lakovic P., Music L., Roos-Hesselink J., Budde R., Gamela T., Wahadat A., Kamp O., Meijers T., Van Melle J. P., Deursen V. M., Crijns H., Bekkers S., Cheriex E., Gilbers M., Kietselaer B., Knackstedt C., Lorusso R., Schalla S., Streukens S., Chamuleau S., Cramer M. -J., Teske A., Van der Spoel T., Wind A., Liesbek O., Lokhorst J., Van Heusden H., Tanis W., Van der Bilt I., Vriend J., De Lange-van Bruggen H., Karijodikoro E., van Dongen E., Schoep J., Stolk V., Axler O., Baumann F., Lebras S., Edvardsen T., Offstad J. T., Beitnes J. O., Helle-Valle T., Skulstad H., Skardal R., Qamar N., Furnaz S., Ahmed B., Butt M. H., Khanzada M. F., Saghir T., Wahid A., Hryniewiecki T., Szymanski P., Marzec K., Misztal-Ogonowska M., Kosmala W., Przewlocka-Kosmala M., Rojek A., Woznicka K., Zachwyc J., Lisowska A., Kaminska M., Kasprzak J., Kowalczyk E., Strzecka D. F., Wejner-Mik P., Trabulo M., Freitas P., Ranchordas S., Rodrigues G., Pinto P., Queiros C., Azevedo J., Marques L., Seabra D., Branco L., Cruz M., Galrinho A., Moreira R., Rio P., Timoteo A. T., Selas M., Cardim N. M., Carmelo V., Neves B. D., Pereira H., Cruz I., Guerra A., Marques A., Pintassilgo I., Tomescu M. C., Trofenciuc N. -M., Andor M., Bordejevic A., Branea H. S., Caruntu F., Cirin L., Citu I. M., Cotoraci C. A., Darabantiu D., Farcas R., Marincu I., Mavrea A., Onel M. F., Parvanescu T., Pop D., Pop-Moldovan A. L., Puticiu M. I., Velcean L. A., Ionac A., Cozma D., Mornos C., Goanta F., Popescu I., Beyer R., Mada R., Rancea R., Rosianu H., Tomoaia R., Stanescu C., Kobalava Z., Karaulova J., Kotova E., Milto A., Pisaryuk A., Povalyaev N., Sorokina M., Alrahimi J., Elshiekh A., Jamiel A., Ahmed A., Al-Mallah M., Attia N., Putnikovic B., Neskovic A., Dimic A., Ivanovic B., Matic S., Trifunovic D., Petrovic J., Kosevic D., Dabic P., Milojevic P., Petrovic I., Stojanovic I., Kovacevic M., Redzek A., Stefanovic M., Susak S., Velicki L., Vulin A., Yeo T. C., Kong W. K. F., Poh K. K., Vilacosta I., El-Nasser M. A., Ferrera C., Olmos C., Iglesias F. C., Blanco-Gonzalez E., Amaro M. B., Germinas A. N., Lopez-Rodriguez E., Adan J. L., Pazos-Lopez P., Loureiro M. P., Perez M. T., Raposeiras-Roubin S., Yas S. R., Suarez-Varela M. -M., Vidal F. V., Garcia-Dorado D., Sambola A., Fernandez-Hidalgo N., Gonzalez-Alujas T., Lozano J., Maisterra O., Pizzi N., Rios R., Tornos P., Bayes-Genis A., Botet L. P., Vallejo N., Berastegui E., Llibre C., Mateu L., Nunez R., Quesada D., Portell D. B., Vinas J. A., Bertran X. A., Tarradellas R. B., Ricon P. L. -O., de Llano C. T., Arnau M. A., Bel A., Blanes M., Osa A., Anguita M., Carrasco F., Castillo J., Zamorano J. L., Mur J. L. M., Alvaro M., Fernandez-Golfin C., Monteagudo J. M., Elorza E. N., Alvarez M. C. F., Balbin J. A., Arminanzas C., de las Revillas F. A., Garcia A. A., Belaustegui M. C., Sampedro M. F., Cuadra M. G., Gutierrez-Diez J. F., Zarauza J., Cuello L. G., Rico C. G., Rodriguez-Alvarez R., Goikoetxea J., Montejo M., Miro J., Almela M., Ambrosioni J., Falces C., Fuster D., Garcia-de-la-Maria C., Hernandez-Meneses M., Llopis J., Marco F., Moreno A., Quintana E., Sandoval E., Tellez A., Tolosana J. M., Vidal B., Ruiz-Zamora I., Ruiz A. B., Girgas E. S., Garcia-Pardo G., Marzo M. G., Oviedo A. R., Jimenez A. V., Abid L., Hammami R., Kammoun S., Mourali M. S., Zghal F. M., Hlima M. B., Boudiche S., Ouali S., Zakhama L., Antit S., Slama I., Gulel O., Sahin M., Sade L. E., Karacaglar E., Kucukoglu S., Cetinarslan O., Sinan U. Y., Canpolat U., Atas H., Dervishova R., Ileri C., Zaky H., Alhashmi J., Baslib F., Tahir J., Zarger P., Woldman S., Menezes L., Primus C., Uppal R., Bvekerwa I., Chandrasekaran B., Kopanska A., Prendergast B., Cannata S., Chambers J., Hancock J., Klein J., Rajani R., Ursi M. P., Dworakowski R., Fife A., Breeze J., Browne-Morgan M., Gunning M., Streather S., Asch F., Zemedkun M., Alyavi B., and Uzokov J.

Published
2022

9. Surgery and outcome of infective endocarditis in octogenarians: prospective data from the ESC EORP EURO-ENDO registry

Author

Pazdernik, M, Iung, B, Mutlu, B, Alla, F, Riezebos, R, Kong, W, Nunes, M, Pierard, L, Srdanovic, I, Yamada, H, De Martino, A, Miglioranza, M, Magne, J, Piper, C, Laroche, C, Maggioni, A, Lancellotti, P, Habib, G, Selton-Suty, C, Ronderos, R, Avegliano, G, Oses, P, Filipini, E, Granada, I, Iribarren, A, Mahia, M, Nacinovich, F, Ressi, S, Obregon, R, Bangher, M, Dho, J, Cartasegna, L, Plastino, M, Novas, V, Shigel, C, Reyes, G, De Santos, M, Gastaldello, N, Fernandez, M, Potito, M, Streitenberger, G, Velazco, P, Casabe, J, Cortes, C, Guevara, E, Salmo, F, Seijo, M, Weidinger, F, Heger, M, Brooks, R, Stollberger, C, Ho, C, Perschy, L, Puskas, L, Goliasch, G, Binder, C, Rosenhek, R, Schneider, M, Winter, M, Hoffer, E, Melissopoulou, M, Lecoq, E, Legrand, D, Jacquet, S, Massoz, M, Dulgheru, R, Marchetta, S, Demal, C, Oury, C, Cosyns, B, Droogmans, S, Kerkhove, D, Motoc, A, Plein, D, Roosens, B, Soens, L, Weytjens, C, Lemoine, I, Rodrigus, I, Paelinck, B, Amsel, B, Unger, P, Konopnicki, D, Beauloye, C, Pasquet, A, Pierard, S, Vancraeynest, D, Vanoverschelde, J, Sinnaeve, F, Andrade, J, Rodrigues, A, Staszko, K, Dos Santos Monteiro, R, Shuha, D, Alcantara, M, Cravo, V, Fazzio, L, Felix, A, Iso, M, Musa, C, Siciliano, A, Filho, F, Braga, J, Silva, R, Vilela, F, Rodrigues, D, Silva, L, Morhy, S, Fischer, C, Vieira, M, Afonso, T, Abreu, J, Falcao, S, Moises, V, Gouvea, A, Joao, G, Mancuso, F, Silva, C, Souza, A, Abboud, C, de Mattos Barretto, R, Ramos, A, Arnoni, R, Assef, J, Togna, D, Le Bihan, D, Miglioli, L, Oliveira, A, Kroll, R, Cortez, D, Gelape, C, De Abreu Ferrari, T, Chan, K, Hay, K, Le, V, Page, M, Poulin, F, Sauve, C, Serri, K, Mercure, C, Beaudoin, J, Pibarot, P, Sebag, I, Rudski, L, Ricafort, G, Barsic, B, Krajinovic, V, Vargovic, M, Separovic-Hanzevacki, J, Lovric, D, Reskovic-Luksic, V, Vincelj, J, Jurinjak, S, Yiannikourides, V, Ioannides, M, Kyriakou, C, Pofaides, C, Masoura, V, Yiangou, K, Pudich, J, Linhart, A, Siranec, M, Marek, J, Blechova, K, Kamenik, M, Pelouch, R, Coufal, Z, Mikulica, M, Griva, M, Jancova, E, Mikulcova, M, Taborsky, M, Precek, J, Jecmenova, M, Latal, J, Widimsky, J, Butta, T, Machacek, S, Vancata, R, Spinar, J, Holicka, M, Long, F, Anzules, N, Carpio, A, Largacha, G, Penaherrera, E, Moreira, D, Mahfouz, E, Elsafty, E, Soliman, A, Zayed, Y, Aboulenein, J, Abdel-Hay, M, Almaghraby, A, Abdelnaby, M, Ahmed, M, Hammad, B, Saleh, Y, Zahran, H, Elgebaly, O, Saad, A, Ali, M, Zeid, A, Sharkawy, R, Meshaal, M, Al Kholy, A, Doss, R, Osama, D, Rizk, H, Elmogy, A, Mishriky, M, Assayag, P, Hatimi, S, Botelho-Nevers, S, Campisi, S, Fuzellier, J, Gagneux-Brunon, A, Pierrard, R, Tulane, C, Detoc, M, Mehalla, T, Boutoille, D, Al Habash, O, Asseray-Madani, N, Biron, C, Brochard, J, Caillon, J, Cueff, C, Le Tourneau, T, Lecompte, A, Lecomte, R, Lefebvre, M, Michel, M, Pattier, S, Delarue, S, Le Bras, M, Orain, J, Faucher, J, Aboyans, V, Beeharry, A, Durox, H, Lacoste, M, Mohty, D, David, A, Pradel, V, Sierra, V, Neykova, A, Bettayeb, B, Elkentaoui, S, Tzvetkov, B, Landry, G, Strady, C, Ainine, K, Baumard, S, Brasselet, C, Tassigny, C, Valente-Pires, V, Lefranc, M, Hoen, B, Lefevre, B, Curlier, E, Callier, C, Fourcade, N, Jobic, Y, Ansard, S, Le Berre, R, Le Roux, P, Le Ven, F, Pouliquen, M, Prat, G, Bouchart, F, Savoure, A, Alarcon, C, Chapuzet, C, Gueit, I, Tribouilloy, C, Bohbot, Y, Peugnet, F, Gun, M, Duval, X, Lescure, X, Ilic-Habensus, E, Sadoul, N, Chevalier, E, Goehringer, F, Huttin, O, Garcia, R, Le Marcis, V, Tattevin, P, Donal, E, Flecher, E, Revest, M, Hubert, S, Casalta, J, Gouriet, F, Arregle, F, Cammilleri, S, Tessonnier, L, Riberi, A, Chirouze, C, Bouiller, K, Brunel, A, Fournier, D, Hustache-Mathieu, L, Klopfenstein, T, Moreau, J, Lim, P, Oliver, L, Ternacle, J, Moussafeur, A, Chavanet, P, Piroth, L, Buisson, M, Mahy, S, Martins, C, Salmon-Rousseau, A, Gohier, S, Borgermann, J, Guckel, D, Horstkotte, D, Brockmeier, B, Winkelmann, E, Hagendorff, A, Grey, D, Nickenig, G, Schueler, R, Ozturk, C, Stohr, E, Hamm, C, Walther, T, Brandt, R, Fruhauf, A, Hartung, C, Hellner, C, Wild, C, Becker, M, Hamada, S, Kaestner, W, Stangl, K, Knebel, F, Baldenhofer, G, Brecht, A, Dreger, H, Isner, C, Pfafflin, F, Stegemann, M, Zahn, R, Fraiture, B, Kilkowski, C, Karcher, A, Klinger, S, Tolksdorf, H, Tousoulis, D, Aggeli, C, Sarri, G, Sideris, S, Venieri, E, Athanassopoulos, G, Tsiapras, D, Armenis, I, Koutsiari, A, Floros, G, Grassos, C, Dragasis, S, Rallidis, L, Varlamos, C, Michalis, L, Naka, K, Bechlioulis, A, Kotsia, A, Lakkas, L, Pappas, K, Papadopoulos, C, Kiokas, S, Lioni, A, Misailidou, S, Barbetseas, J, Bonou, M, Kapelios, C, Tomprou, I, Zerva, K, Manolis, A, Hamodraka, E, Athanasiou, D, Haralambidis, G, Poulimenos, L, Samaras, H, Nagy, A, Bartykowszki, A, Gara, E, Sengupta, S, Mungulmare, K, Kasliwal, R, Bansal, M, Bhan, A, Ranjan, S, Kyavar, M, Maleki, M, Bezanjani, F, Sadeghpour, A, Alizadehasl, A, Boudagh, S, Ghavidel, A, Moradnejad, P, Pasha, H, Ghadrdoost, B, Gilon, D, Strahilevitz, J, 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A, Ahmed, A, Al-Mallah, M, Attia, N, Putnikovic, B, Neskovic, A, Dimic, A, Ivanovic, B, Matic, S, Trifunovic, D, Petrovic, J, Kosevic, D, Dabic, P, Milojevic, P, Petrovic, I, Stojanovic, I, Kovacevic, M, Redzek, A, Stefanovic, M, Susak, S, Velicki, L, Vulin, A, Yeo, T, Poh, K, Vilacosta, I, Nasser, M, Ferrera, C, Olmos, C, Iglesias, F, Blanco-Gonzalez, E, Amaro, M, Germinas, A, Lopez-Rodriguez, E, Adan, J, Pazos-Lopez, P, Loureiro, M, Perez, M, Raposeiras-Roubin, S, Yas, S, Suarez-Varela, M, Vidal, F, Garcia-Dorado, D, Sambola, A, Fernandez-Hidalgo, N, Gonzalez-Alujas, T, Lozano, J, Maisterra, O, Pizzi, N, Rios, R, Tornos, P, Bayes-Genis, A, Botet, L, Vallejo, N, Berastegui, E, Llibre, C, Mateu, L, Nunez, R, Quesada, D, Portell, D, Vinas, J, Bertran, X, Tarradellas, R, Ricon, P, de Llano, C, Arnau, M, Bel, A, Blanes, M, Osa, A, Anguita, M, Carrasco, F, Castillo, J, Zamorano, J, Mur, J, Alvaro, M, Fernandez-Golfin, C, Monteagudo, J, Elorza, E, Alvarez, M, Balbin, J, Arminanzas, C, de 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Streather, S, Asch, F, Zemedkun, M, Alyavi, B, Uzokov, J, Pazdernik M., Iung B., Mutlu B., Alla F., Riezebos R., Kong W., Nunes M. C. P., Pierard L., Srdanovic I., Yamada H., De Martino A., Miglioranza M. H., Magne J., Piper C., Laroche C., Maggioni A. P., Lancellotti P., Habib G., Selton-Suty C., Ronderos R., Avegliano G., Oses P. F., Filipini E., Granada I., Iribarren A., Mahia M., Nacinovich F., Ressi S., Obregon R., Bangher M., Dho J., Cartasegna L., Plastino M. L., Novas V., Shigel C., Reyes G., De Santos M., Gastaldello N., Fernandez M. G., Potito M., Streitenberger G., Velazco P., Casabe J. H., Cortes C., Guevara E., Salmo F., Seijo M., Weidinger F., Heger M., Brooks R., Stollberger C., Ho C. -Y., Perschy L., Puskas L., Goliasch G., Binder C., Rosenhek R., Schneider M., Winter M. -P., Hoffer E., Melissopoulou M., Lecoq E., Legrand D., Jacquet S., Massoz M., Dulgheru R., Marchetta S., DEmal C., Oury C., Cosyns B., Droogmans S., Kerkhove D., Motoc A., Plein D., Roosens B., Soens L., Weytjens C., Lemoine I., Rodrigus I., Paelinck B., Amsel B., Unger P., Konopnicki D., Beauloye C., Pasquet A., Pierard S., Vancraeynest D., Vanoverschelde J. L., Sinnaeve F., Andrade J. L., Rodrigues A. C. T., Staszko K., Dos Santos Monteiro R., Shuha D. L., Alcantara M., Cravo V., Fazzio L., Felix A., Iso M., Musa C., Siciliano A. P., Filho F. V., Braga J., Rodrigues A., Silva R., Vilela F., Rodrigues D., Silva L., Morhy S., Fischer C., Vieira M., Afonso T., Abreu J., Falcao S. N., Moises V., Gouvea A., Joao G., Mancuso F., Silva C., Souza A. C., Abboud C. S., de Mattos Barretto R. B., Ramos A., Arnoni R., Assef J. E., Togna D. J. D., Le Bihan D., Miglioli L., Oliveira A. P. R., Kroll R. T. M., Cortez D., Gelape C. L., De Abreu Ferrari T. C., Chan K. -L., Hay K., Le V., Page M., Poulin F., Sauve C., Serri K., Mercure C., Beaudoin J., Pibarot P., Sebag I., Rudski L., Ricafort G., Barsic B., Krajinovic V., Vargovic M., Separovic-Hanzevacki J., Lovric D., Reskovic-Luksic V., Vincelj J., Jurinjak S. J., Yiannikourides V., Ioannides M., Kyriakou C., Pofaides C., Masoura V., Yiangou K., Pudich J., Linhart A., Siranec M., Marek J., Blechova K., Kamenik M., Pelouch R., Coufal Z., Mikulica M., Griva M., Jancova E., Mikulcova M., Taborsky M., Precek J., Jecmenova M., Latal J., Widimsky J., Butta T., Machacek S., Vancata R., Spinar J., Holicka M., Long F. P. C., Anzules N., Carpio A. B., Largacha G., Penaherrera E., Moreira D., Mahfouz E., Elsafty E., Soliman A., Zayed Y., Aboulenein J., Abdel-Hay M., Almaghraby A., Abdelnaby M., Ahmed M., Hammad B., Saleh Y., Zahran H., Elgebaly O., Saad A., Ali M., Zeid A., Sharkawy R. E., Meshaal M., Al Kholy A., Doss R., Osama D., Rizk H., Elmogy A., Mishriky M., Assayag P., Hatimi S. E., Botelho-Nevers S. -E., Campisi S., Fuzellier J. -F., Gagneux-Brunon A., Pierrard R., Tulane C., Detoc M., Mehalla T., Boutoille D., Al Habash O., Asseray-Madani N., Biron C., Brochard J., Caillon J., Cueff C., Le Tourneau T., Lecompte A. S., Lecomte R., Lefebvre M., Michel M. M. M., Pattier S., Delarue S., Le Bras M., Orain J., Faucher J. -F., Aboyans V., Beeharry A., Durox H., Lacoste M., Mohty D., David A., Pradel V., Sierra V., Neykova A., Bettayeb B., Elkentaoui S., Tzvetkov B., Landry G., Strady C., Ainine K., Baumard S., Brasselet C., Tassigny C., Valente-Pires V., Lefranc M., Hoen B., Lefevre B., Curlier E., Callier C., Fourcade N., Jobic Y., Ansard S., Le Berre R., Le Roux P., Le Ven F., Pouliquen M. -C., Prat G., Bouchart F., Savoure A., Alarcon C., Chapuzet C., Gueit I., Tribouilloy C., Bohbot Y., Peugnet F., Gun M., Duval X., Lescure X., Ilic-Habensus E., Sadoul N., Chevalier E., Goehringer F., Huttin O., Garcia R., Le Marcis V., Tattevin P., Donal E., Flecher E., Revest M., Hubert S., Casalta J. -P., Gouriet F., Arregle F., Cammilleri S., Tessonnier L., Riberi A., Chirouze C., Bouiller K., Brunel A. -S., Fournier D., Hustache-Mathieu L., Klopfenstein T., Moreau J., Lim P., Oliver L., Ternacle J., Moussafeur A., Chavanet P., Piroth L., Buisson M., Mahy S., Martins C., Salmon-Rousseau A., Gohier S., Borgermann J., Guckel D., Horstkotte D., Brockmeier B., Winkelmann E., Hagendorff A., Grey D., Nickenig G., Schueler R., Ozturk C., Stohr E., Hamm C., Walther T., Brandt R., Fruhauf A. -C., Hartung C. T., Hellner C., Wild C., Becker M., Hamada S., Kaestner W., Stangl K., Knebel F., Baldenhofer G., Brecht A., Dreger H., Isner C., Pfafflin F., Stegemann M., Zahn R., Fraiture B., Kilkowski C., Karcher A. -K., Klinger S., Tolksdorf H., Tousoulis D., Aggeli C., Sarri G., Sideris S., Venieri E., Athanassopoulos G., Tsiapras D., Armenis I., Koutsiari A., Floros G., Grassos C., Dragasis S., Rallidis L., Varlamos C., Michalis L., Naka K., Bechlioulis A., Kotsia A., Lakkas L., Pappas K., Papadopoulos C., Kiokas S., Lioni A., Misailidou S., Barbetseas J., Bonou M., Kapelios C., Tomprou I., Zerva K., Manolis A., Hamodraka E., Athanasiou D., Haralambidis G., Poulimenos L., Samaras H., Nagy A., Bartykowszki A., Gara E., Sengupta S., Mungulmare K., Kasliwal R., Bansal M., Bhan A., Ranjan S., Kyavar M., Maleki M., Bezanjani F. N., Sadeghpour A., Alizadehasl A., Boudagh S., Ghavidel A., Moradnejad P., Pasha H. R., Ghadrdoost B., Gilon D., Strahilevitz J., Israel S., Wanounou M., d'Agostino C., Colonna P., De Michele L., Fumarola F., Stante M., Marchionni N., Scheggi V., Alterini B., Del Pace S., Stefano P., Sparano C., Badano L., Muraru D., Ruozi N., Tenaglia R., Limbruno U., Cresti A., Baratta P., Solari M., Giannattasio C., Moreo A., De Chiara B., Montero B. L., Musca F., Orcese C. A., Panzeri F., Russo C. F., Spano F., Alfieri O., De Bonis M., Agricola E., Busnardo E., Carletti S., Castiglioni B., Chiappetta S., Del Forno B., Ferrara D., Guffanti M., Iaci G., Lapenna E., Nisi T., Oltolini C., Pajoro U., Pasciuta R., Ripa M., Scarpellini P., Din C. T., Meneghin R., Schiavi D., Piscione F., Citro R., Benvenga R. M., Greco L., Prota C., Radano I., Soriente L., Bellino M., Di Vece D., Santini F., Salsano A., Olivieri G. M., Turrini F., Messora R., Tondi S., Olaru A., Agnoletto V., Grassi L., Leonardi C., Sansoni S., Del Ponte S., Dato G. M. A., Ohte N., Kikuchi S., Wakami K., Aonuma K., Seo Y., Ishizu T., Machino-Ohtsuka T., Yamamoto M., Iida N., Nakajima H., Nakagawa Y., Izumi C., Amano M., Miyake M., Takahashi K., Shiojima I., Miyasaka Y., Maeba H., Suwa Y., Taniguchi N., Tsujimoto S., Kitai T., Ota M., Yuda S., Sasaki S., Hagiwara N., Yamazaki K., Ashihara K., Arai K., Saitou C., Saitou S., Suzuki G., Shibata Y., Watanabe N., Nishino S., Ashikaga K., Kuriyama N., Mahara K., Abe K., Fujimaki H., Okubo T., Shitan H., Takanashi S., Terada M., Yamamoto H., Sata M., Kusunose K., Saijo Y., Seno H., Yuichiro O., Sakata Y., Mizuno H., Nakatani S., Onishi T., Sengoku K., Sera F., Park S. W., Kyoung K. E., Yeon L. G., Hwang J. -W., Jin-Oh C., Park S. -J., Sang-Chol L., Sung-A C., Jang S. Y., Kang D. -H., Heo R., Lee S., Song J. -M., Jung E., Plisiene J., Dambrauskaite A., Gruodyte G., Jonkaitiene R., Vaskelyte J., Mizariene V., Atkocaityte J., Zvirblyte R., Sow R., Codreanu A., De la Vega E. C. L., Michaux C., Staub T., Jacobs-Orazi L., Azzopardi C. M., Xuereb R. G., Piscopo T., Borg D., Casha R., Farrugia J., Fenech M., Pllaha E., Vella C., Yamagata K., Grib L., Raevschi E., Grejdieru A., Balan G., Cardaniuc I., Cardaniuc L., Corcea V., Feodorovici A., Gaina V., Girbu L., Jimbei P., Kravcenco D., Panfile E., Prisacari E., Samohvalov E., Samohvalov S., Sceglova N., Benesco I., Marian V., Sumarga N., Mirocevic M., Bozovic B., Bulatovic N., Lakovic P., Music L., Roos-Hesselink J., Budde R., Gamela T., Wahadat A., Kamp O., Meijers T., Van Melle J. P., Deursen V. M., Crijns H., Bekkers S., Cheriex E., Gilbers M., Kietselaer B., Knackstedt C., Lorusso R., Schalla S., Streukens S., Chamuleau S., Cramer M. -J., Teske A., Van der Spoel T., Wind A., Liesbek O., Lokhorst J., Van Heusden H., Tanis W., Van der Bilt I., Vriend J., De Lange-van Bruggen H., Karijodikoro E., van Dongen E., Schoep J., Stolk V., Axler O., Baumann F., Lebras S., Edvardsen T., Offstad J. T., Beitnes J. O., Helle-Valle T., Skulstad H., Skardal R., Qamar N., Furnaz S., Ahmed B., Butt M. H., Khanzada M. F., Saghir T., Wahid A., Hryniewiecki T., Szymanski P., Marzec K., Misztal-Ogonowska M., Kosmala W., Przewlocka-Kosmala M., Rojek A., Woznicka K., Zachwyc J., Lisowska A., Kaminska M., Kasprzak J., Kowalczyk E., Strzecka D. F., Wejner-Mik P., Trabulo M., Freitas P., Ranchordas S., Rodrigues G., Pinto P., Queiros C., Azevedo J., Marques L., Seabra D., Branco L., Cruz M., Galrinho A., Moreira R., Rio P., Timoteo A. T., Selas M., Cardim N. M., Carmelo V., Neves B. D., Pereira H., Cruz I., Guerra A., Marques A., Pintassilgo I., Tomescu M. C., Trofenciuc N. -M., Andor M., Bordejevic A., Branea H. S., Caruntu F., Cirin L., Citu I. M., Cotoraci C. A., Darabantiu D., Farcas R., Marincu I., Mavrea A., Onel M. F., Parvanescu T., Pop D., Pop-Moldovan A. L., Puticiu M. I., Velcean L. 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Abstract

Purpose: High mortality and a limited performance of valvular surgery are typical features of infective endocarditis (IE) in octogenarians, even though surgical treatment is a major determinant of a successful outcome in IE. Methods: Data from the prospective multicentre ESC EORP EURO-ENDO registry were used to assess the prognostic role of valvular surgery depending on age. Results: As compared to < 80 yo patients, ≥ 80 yo had lower rates of theoretical indication for valvular surgery (49.1% vs. 60.3%, p < 0.001), of surgery performed (37.0% vs. 75.5%, p < 0.001), and a higher in-hospital (25.9% vs. 15.8%, p < 0.001) and 1-year mortality (41.3% vs. 22.2%, p < 0.001). By multivariable analysis, age per se was not predictive of 1-year mortality, but lack of surgical procedures when indicated was strongly predictive (HR 2.98 [2.43–3.66]). By propensity analysis, 304 ≥ 80 yo were matched to 608 < 80 yo patients. Propensity analysis confirmed the lower rate of indication for valvular surgery (51.3% vs. 57.2%, p = 0.031) and of surgery performed (35.3% vs. 68.4%, p < 0.0001) in ≥ 80 yo. Overall mortality remained higher in ≥ 80 yo (in-hospital: HR 1.50[1.06–2.13], p = 0.0210; 1-yr: HR 1.58[1.21–2.05], p = 0.0006), but was not different from that of < 80 yo among those who had surgery (in-hospital: 19.7% vs. 20.0%, p = 0.4236; 1-year: 27.3% vs. 25.5%, p = 0.7176). Conclusion: Although mortality rates are consistently higher in ≥ 80 yo patients than in < 80 yo patients in the general population, mortality of surgery in ≥ 80 yo is similar to < 80 yo after matching patients. These results confirm the importance of a better recognition of surgical indication and of an increased performance of surgery in ≥ 80 yo patients.

Published
2022

10. Surgery and outcome of infective endocarditis in octogenarians: prospective data from the ESC EORP EURO-ENDO registry

Author

Pazdernik, Michal, Iung, Bernard, Mutlu, Bulent, Alla, François, Riezebos, Robert, Kong, William, Nunes, Maria Carmo Pereira, Pierard, Luc, Srdanovic, Ilija, Yamada, Hirotsugu, de Martino, Andrea, Miglioranza, Marcelo Haertel, Magne, Julien, Piper, Cornelia, Laroche, C. cile, Maggioni, Aldo P., Lancellotti, Patrizio, Habib, Gilbert, Selton-Suty, Christine, Ronderos, R., Avegliano, G., Oses, P. Fernandez, Filipini, E., Granada, I., Iribarren, A., Mahia, M., Nacinovich, F., Ressi, S., Obregon, R., Bangher, M., Dho, J., Cartasegna, L., Plastino, M. L., Novas, V., Shigel, C., Reyes, G., de Santos, M., Gastaldello, N., Fernandez, M. Granillo, Potito, M., Streitenberger, G., Velazco, P., Casabé, J. H., Cortes, C., Guevara, E., Salmo, F., Seijo, M., Weidinger, F., Heger, M., Brooks, R., Stöllberger, C., Ho, C. Y., Perschy, L., Puskas, L., Goliasch, G., Binder, C., Rosenhek, R., Schneider, M., Winter, M. P., Hoffer, E., Melissopoulou, M., Lecoq, E., Legrand, D., Jacquet, S., Massoz, M., Lancellotti, P., Pierard, L., Dulgheru, R., Marchetta, S., D´Emal, C., Oury, C., Cosyns, B., Droogmans, S., Kerkhove, D., Motoc, A., Plein, D., Roosens, B., Soens, L., Weytjens, C., Lemoine, I., Rodrigus, I., Paelinck, B., Amsel, B., Unger, P., Konopnicki, D., Beauloye, C., Pasquet, A., Pierard, S., Vancraeynest, D., Vanoverschelde, J. L., Sinnaeve, F., Andrade, J. L., Rodrigues, A. C. Tude, Staszko, K., Dos Santos Monteiro, R., Miglioranza, M. H., Shuha, D. L., Alcantara, M., Cravo, V., Fazzio, L., Felix, A., Iso, M., Musa, C., Siciliano, A. P., Filho, F. Villaca, Braga, J., Rodrigues, A., Silva, R., Vilela, F., Rodrigues, D., Silva, L., Morhy, S., Fischer, C., Vieira, M., Afonso, T., Abreu, J., Falcao, S. N., Moises, V., Gouvea, A., João, G., Mancuso, F., Silva, C., Souza, A. C., Abboud, C. S., de Mattos Barretto, R. Bellio, Ramos, A., Arnoni, R., Assef, J. E., Togna, D. J. 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P., Dworakowski, R., Fife, A., Breeze, J., Browne-Morgan, M., Gunning, M., Streather, S., Asch, F., Zemedkun, M., Alyavi, B., Uzokov, J., Cardiology, ACS - Heart failure & arrhythmias, Pazdernik, M, Iung, B, Mutlu, B, Alla, F, Riezebos, R, Kong, W, Nunes, M, Pierard, L, Srdanovic, I, Yamada, H, De Martino, A, Miglioranza, M, Magne, J, Piper, C, Laroche, C, Maggioni, A, Lancellotti, P, Habib, G, Selton-Suty, C, Ronderos, R, Avegliano, G, Oses, P, Filipini, E, Granada, I, Iribarren, A, Mahia, M, Nacinovich, F, Ressi, S, Obregon, R, Bangher, M, Dho, J, Cartasegna, L, Plastino, M, Novas, V, Shigel, C, Reyes, G, De Santos, M, Gastaldello, N, Fernandez, M, Potito, M, Streitenberger, G, Velazco, P, Casabe, J, Cortes, C, Guevara, E, Salmo, F, Seijo, M, Weidinger, F, Heger, M, Brooks, R, Stollberger, C, Ho, C, Perschy, L, Puskas, L, Goliasch, G, Binder, C, Rosenhek, R, Schneider, M, Winter, M, Hoffer, E, Melissopoulou, M, Lecoq, E, Legrand, D, Jacquet, S, Massoz, M, Dulgheru, R, Marchetta, S, 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Dworakowski, R, Fife, A, Breeze, J, Browne-Morgan, M, Gunning, M, Streather, S, Asch, F, Zemedkun, M, Alyavi, B, Uzokov, J, Clinical sciences, Cardio-vascular diseases, Medical Imaging, Pazdernik M., Iung B., MUTLU B., Alla F., Riezebos R., Kong W., Pereira Nunes M. C., Pierard L., Srdanovic I., Yamada H., et al., Bordeaux population health (BPH), Université de Bordeaux (UB)-Institut de Santé Publique, d'Épidémiologie et de Développement (ISPED)-Institut National de la Santé et de la Recherche Médicale (INSERM), Cardiology Dept, CHU Limoges, INSERM 1094, University Hospital Dupuytren, 87042, Limoges, Epidémiologie des Maladies Chroniques en zone tropicale (EpiMaCT), CHU Limoges-Institut d'Epidémiologie Neurologique et de Neurologie Tropicale-Institut National de la Santé et de la Recherche Médicale (INSERM)-OmégaHealth (ΩHealth), Université de Limoges (UNILIM)-Université de Limoges (UNILIM), Microbes évolution phylogénie et infections (MEPHI), Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS), Département de Cardiologie [Hôpital de la Timone - APHM], Assistance Publique - Hôpitaux de Marseille (APHM)- Hôpital de la Timone [CHU - APHM] (TIMONE), Mécanismes physiopathologiques et conséquences des calcifications vasculaires - UR UPJV 7517 (MP3CV), Université de Picardie Jules Verne (UPJV)-CHU Amiens-Picardie, European Infective Endocarditis Registry (Euro-Endo), Abbott Vascular, AstraZeneca, ResMed, Sanofi, Servier, Vifor Pharma, Bayer, Boehringer Ingelheim, Bristol-Myers Squibb, Pfizer, Daiichi Sankyo Europe, Eli Lilly and Company, Gedeon Richter, and Novartis Pharma

Subjects
Microbiology (medical), Prognosi, Immunology, Infective endocarditi, Life Sciences (LIFE), INTERNATIONAL COLLABORATION, PROFILE, AGE, Elderly, Propensity analysis, Yaşam Bilimleri, Health Sciences, RISK, İmmünoloji, General Immunology and Microbiology, Infective endocarditis, Prognosis, Surgery, Temel Bilimler, Life Sciences, General Medicine, INFECTIOUS DISEASES, MED/11 - MALATTIE DELL'APPARATO CARDIOVASCOLARE, BULAŞICI HASTALIKLAR, Yaşam Bilimleri (LIFE), [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie, Propensity analysi, Natural Sciences
Abstract

Purpose: High mortality and a limited performance of valvular surgery are typical features of infective endocarditis (IE) in octogenarians, even though surgical treatment is a major determinant of a successful outcome in IE. Methods: Data from the prospective multicentre ESC EORP EURO-ENDO registry were used to assess the prognostic role of valvular surgery depending on age. Results: As compared to < 80yo patients, ≥ 80yo had lower rates of theoretical indication for valvular surgery (49.1% vs. 60.3%, p < 0.001), of surgery performed (37.0% vs. 75.5%, p < 0.001), and a higher in-hospital (25.9% vs. 15.8%, p < 0.001) and 1-year mortality (41.3% vs. 22.2%, p < 0.001). By multivariable analysis, age per se was not predictive of 1-year mortality, but lack of surgical procedures when indicated was strongly predictive (HR 2.98 [2.43–3.66]). By propensity analysis, 304 ≥ 80yo were matched to 608 < 80yo patients. Propensity analysis confirmed the lower rate of indication for valvular surgery (51.3% vs. 57.2%, p = 0.031) and of surgery performed (35.3% vs. 68.4%, p < 0.0001) in ≥ 80yo. Overall mortality remained higher in ≥ 80yo (in-hospital: HR 1.50[1.06–2.13], p = 0.0210; 1-yr: HR 1.58[1.21–2.05], p = 0.0006), but was not different from that of < 80yo among those who had surgery (in-hospital: 19.7% vs. 20.0%, p = 0.4236; 1-year: 27.3% vs. 25.5%, p = 0.7176). Conclusion: Although mortality rates are consistently higher in ≥ 80yo patients than in < 80yo patients in the general population, mortality of surgery in ≥ 80yo is similar to < 80yo after matching patients. These results confirm the importance of a better recognition of surgical indication and of an increased performance of surgery in ≥ 80yo patients.

Published
2022

11. Characteristics, management, and outcomes of patients with left-sided infective endocarditis complicated by heart failure:a substudy of the ESC-EORP EURO-ENDO (European infective endocarditis) registry

Author

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Filipini, E, Obregon, R, Bangher, M, Dho, J, Cartasegna, L, Plastino, M, Novas, V, Shigel, C, De Santos, M, Gastaldello, N, Granillo Fernandez, M, Potito, M, Streitenberger, G, Velazco, P, Casabe, J, Cortes, C, Guevara, E, Salmo, F, Seijo, M, Weidinger, F, Heger, M, Brooks, R, Stollberger, C, Ho, C, Perschy, L, Puskas, L, Binder, C, Rosenhek, R, Schneider, M, Winter, M, Hoffer, E, Lecoq, E, Legrand, D, Jacquet, S, Massoz, M, Pierard, L, Marchetta, S, Dulgheru, R, D'Emal, C, Oury, C, Droogmans, S, Kerkhove, D, Plein, D, Soens, L, Weytjens, C, Motoc, A, Roosens, B, Lemoine, I, Rodrigus, I, Paelinck, B, Amsel, B, Unger, P, Konopnicki, D, Beauloye, C, Pasquet, A, Vanoverschelde, J, Pierard, S, Vancraeynest, D, Sinnaeve, F, Andrade, J, Staszko, K, Dos Santos Monteiro, R, Miglioranza, M, Shuha, D, Alcantara, M, Cravo, V, Fazzio, L, Felix, A, Iso, M, Musa, C, Siciliano, A, Villaca Filho, F, Rodrigues, A, Vilela, F, Braga, J, Silva, R, Rodrigues, D, Silva, L, Morhy, S, Fischer, C, Vieira, M, Afonso, T, Abreu, J, Falcao, S, Moises, V, Gouvea, A, Mancuso, F, Souza, A, Silva, C, Joao, G, Abboud, C, Bellio de Mattos Barretto, R, Ramos, A, Arnoni, R, Assef, J, Della Togna, D, Le Bihan, D, Miglioli, L, Romero Oliveira, A, Tadeu Magro Kroll, R, Cortez, D, Gelape, C, Peirira Nunes, M, De Abreu Ferrari, T, Hay, K, Le, V, Page, M, Poulin, F, Sauve, C, Serri, K, Mercure, C, Beaudoin, J, Pibarot, P, Sebag, I, Rudski, L, Ricafort, G, Barsic, B, Krajinovic, V, Vargovic, M, Lovric, D, Reskovic-Luksic, V, Vincelj, J, Jaksic Jurinjak, S, Yiannikourides, V, Ioannides, M, Pofaides, C, Masoura, V, Pudich, J, Linhart, A, Siranec, M, Marek, J, Blechova, K, Kamenik, M, Pelouch, R, Coufal, Z, Mikulica, M, Griva, M, Jancova, E, Mikulcova, M, Taborsky, M, Precek, J, Jecmenova, M, Latal, J, Widimsky, J, Butta, T, Machacek, S, Vancata, R, Spinar, J, Holicka, M, Pow Chon Long, F, Anzules, N, Bajana Carpio, A, Largacha, G, Penaherrera, E, Moreira, D, Mahfouz, E, Elsafty, E, Soliman, A, Zayed, Y, Aboulenein, J, Abdel-Hay, M, Almaghraby, A, Abdelnaby, M, Ahmed, M, Hammad, B, Saleh, Y, Zahran, H, Elgebaly, O, Saad, A, Ali, M, Zeid, A, El Sharkawy, R, Al Kholy, A, Doss, R, Osama, D, Rizk, H, Elmogy, A, Mishriky, M, Assayag, P, El Hatimi, S, Hubert, S, Casalta, J, Gouriet, F, Arregle, F, Cammilleri, S, Tessonnier, L, Riberi, A, Botelho-Nevers, E, Gagneux-Brunon, A, Pierrard, R, Tulane, C, Campisi, S, Fuzellier, J, Detoc, M, Mehalla, T, Boutoille, D, Lecompte, A, Lefebvre, M, Pattier, S, Al Habash, O, Asseray-Madani, N, Biron, C, Brochard, J, Caillon, J, Cueff, C, Le Tourneau, T, Lecomte, R, Magali Michel, M, Orain, J, Delarue, S, Le Bras, M, Faucher, J, Aboyans, V, Beeharry, A, Durox, H, Lacoste, M, Magne, J, Mohty, D, David, A, Pradel, V, Sierra, V, Neykova, A, Bettayeb, B, Elkentaoui, S, Tzvetkov, B, Landry, G, Strady, C, Ainine, K, Baumard, S, Brasselet, C, Tassigny, C, Valente-Pires, V, Lefranc, M, Hoen, B, Lefevre, B, Curlier, E, Callier, C, Fourcade, N, Jobic, Y, Ansard, S, Le Berre, R, Le Ven, F, Pouliquen, M, Prat, G, Le Roux, P, Bouchart, F, Savoure, A, Alarcon, C, Chapuzet, C, Gueit, I, Peugnet, F, Gun, M, Duval, X, Lescure, X, Ilic-Habensus, E, Sadoul, N, Selton-Suty, C, Alla, F, Goehringer, F, Huttin, O, Chevalier, E, Garcia, R, Le Marcis, V, Tattevin, P, Flecher, E, Revest, M, Bouiller, K, Hustache-Mathieu, L, Klopfenstein, T, Moreau, J, Fournier, D, Brunel, A, Lim, P, Oliver, L, Ternacle, J, Moussafeur, A, Chavanet, P, Piroth, L, Salmon-Rousseau, A, Buisson, M, Mahy, S, Martins, C, Gohier, S, Axler, O, Baumann, F, Lebras, S, Piper, C, Guckel, D, Borgermann, J, Horstkotte, D, Winkelmann, E, Brockmeier, B, Grey, D, Nickenig, G, Schueler, R, Ozturk, C, Hamm, C, Walther, T, Brandt, R, Fruhauf, A, Hartung, C, Hellner, C, Wild, C, Becker, M, Hamada, S, Kaestner, W, Stangl, K, Knebel, F, Baldenhofer, G, Brecht, A, Dreger, H, Isner, C, Pfafflin, F, Stegemann, M, Zahn, R, Fraiture, B, Kilkowski, C, Karcher, A, Klinger, S, Tolksdorf, H, Tousoulis, D, Aggeli, C, Sideris, S, Venieri, E, Sarri, G, Tsiapras, D, Armenis, I, Koutsiari, A, Floros, G, Grassos, C, Dragasis, S, Rallidis, L, Varlamos, C, Michalis, L, Naka, K, Bechlioulis, A, Kotsia, A, Lakkas, L, Pappas, K, Papadopoulos, C, Kiokas, S, Lioni, A, Misailidou, S, Barbetseas, J, Bonou, M, Kapelios, C, Tomprou, I, Zerva, K, Manolis, A, Hamodraka, E, Athanasiou, D, Haralambidis, G, Samaras, H, Poulimenos, L, Nagy, A, Bartykowszki, A, Gara, E, Mungulmare, K, Kasliwal, R, Bansal, M, Ranjan, S, Bhan, A, Kyavar, M, Maleki, M, Bezanjani, F, Alizadehasl, A, Boudagh, S, Ghavidel, A, Moradnejad, P, Pasha, H, Ghadrdoost, B, Gilon, D, Strahilevitz, J, Wanounou, M, Israel, S, D'Agostino, C, Colonna, P, De Michele, L, Fumarola, F, Stante, M, Marchionni, N, Alterini, B, Del Pace, S, Stefano, P, Sparano, C, Ruozi, N, Tenaglia, R, Muraru, D, Limbruno, U, Cresti, A, Baratta, P, Solari, M, Giannattasio, C, Moreo, A, De Chiara, B, Lopez Montero, B, Musca, F, Orcese, C, Panzeri, F, Spano, F, Russo, C, 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Fujimaki, H, Shitan, H, Yamamoto, H, Abe, K, Terada, M, Takanashi, S, Sata, M, Yamada, H, Kusunose, K, Saijo, Y, Seno, H, Yuichiro, O, Onishi, T, Sera, F, Nakatani, S, Mizuno, H, Sengoku, K, Park, S, Kyoung, K, Yeon, L, Hwang, J, Jin-Oh, C, Sang-Chol, L, Sung-A, C, Jang, S, Heo, R, Lee, S, Song, J, Jung, E, Plisiene, J, Dambrauskaite, A, Gruodyte, G, Jonkaitiene, R, Mizariene, V, Atkocaityte, J, Zvirblyte, R, Codreanu, A, Staub, T, Michaux, C, De la Vega, E, Jacobs-Orazi, L, Mallia Azzopardi, C, Xuereb, R, Piscopo, T, Farrugia, J, Fenech, M, Pllaha, E, Vella, C, Borg, D, Casha, R, Grib, L, Raevschi, E, Grejdieru, A, Kravcenco, D, Prisacari, E, Samohvalov, E, Samohvalov, S, Sceglova, N, Panfile, E, Cardaniuc, L, Corcea, V, Feodorovici, A, Gaina, V, Girbu, L, Jimbei, P, Balan, G, Cardaniuc, I, Benesco, I, Marian, V, Sumarga, N, Bozovic, B, Bulatovic, N, Lakovic, P, Music, L, Budde, R, Wahadat, A, Gamela, T, Meijers, T, Van Melle, J, Deursen, V, Crijns, H, Bekkers, S, Cheriex, E, Gilbers, M, Kietselaer, B, Knackstedt, C, Lorusso, R, Schalla, S, Streukens, S, Chamuleau, S, Cramer, M, Teske, A, Van der Spoel, T, Wind, A, Lokhorst, J, Liesbek, O, Van Heusden, H, Tanis, W, Van der Bilt, I, Vriend, J, De Lange-van Bruggen, H, Karijodikoro, E, Riezebos, R, van Dongen, E, Schoep, J, Stolk, V, Offstad, J, Beitnes, J, Helle-Valle, T, Skulstad, H, Skardal, R, Qamar, N, Furnaz, S, Ahmed, B, Butt, M, Khanzada, M, Saghir, T, Wahid, A, Hryniewiecki, T, Szymanski, P, Marzec, K, Misztal-Ogonowska, M, Kosmala, W, Przewlocka-Kosmala, M, Rojek, A, Woznicka, K, Zachwyc, J, Lisowska, A, Kaminska, M, Kasprzak, J, Kowalczyk, E, Strzecka, D, Wejner-Mik, P, Trabulo, M, Freitas, P, Ranchordas, S, Rodrigues, G, Pinto, P, Queiros, C, Azevedo, J, Marques, L, Seabra, D, Cruz, M, Galrinho, A, Moreira, R, Rio, P, Timoteo, A, Selas, M, Carmelo, V, Duque Neves, B, Pereira, H, Guerra, A, Marques, A, Pintassilgo, I, Tomescu, M, Trofenciuc, N, Andor, M, Bordejevic, A, Branea, H, Caruntu, F, Velcean, L, Mavrea, A, Onel, M, Parvanescu, T, Pop, D, Pop-Moldovan, A, Puticiu, M, Cirin, L, Citu, I, Cotoraci, C, Darabantiu, D, Farcas, R, Marincu, I, Ionac, A, Cozma, D, Mornos, C, Goanta, F, Popescu, I, Beyer, R, Mada, R, Rancea, R, Tomoaia, R, Rosianu, H, Stanescu, C, Kobalava, Z, Karaulova, J, Kotova, E, Milto, A, Pisaryuk, A, Povalyaev, N, Sorokina, M, Alrahimi, J, Elshiekh, A, Jamiel, A, Ahmed, A, Attia, N, Putnikovic, B, Dimic, A, Ivanovic, B, Matic, S, Trifunovic, D, Petrovic, J, Kosevic, D, Stojanovic, I, Petrovic, I, Dabic, P, Milojevic, P, Srdanovic, I, Susak, S, Velicki, L, Vulin, A, Kovacevic, M, Redzek, A, Stefanovic, M, Yeo, T, Poh, K, Vilacosta, I, Ferrera, C, Abd El- Nasser, M, Calvo Iglesias, F, Blanco-Gonzalez, E, Bravo Amaro, M, Lopez-Rodriguez, E, Lugo Adan, J, Germinas, A, Pazos-Lopez, P, Pereira Loureiro, M, Perez, M, Raposeiras-Roubin, S, Rasheed Yas, S, Suarez-Varela, M, Vasallo Vidal, F, Garcia-Dorado, D, Fernandez-Hidalgo, N, Gonzalez-Alujas, T, Lozano, J, Maisterra, O, Pizzi, N, Rios, R, Bayes-Genis, A, Pedro Botet, L, Vallejo, N, Llibre, C, Mateu, L, Nunez, R, Quesada, D, Berastegui, E, Bosch Portell, D, Aboal Vinas, J, Albert Bertran, X, Brugada Tarradellas, R, Loma-Osorio Ricon, P, Tiron de Llano, C, Arnau, M, Bel, A, Blanes, M, Osa, A, Anguita, M, Carrasco, F, Castillo, J, Zamorano, J, Moya Mur, J, Alvaro, M, Fernandez-Golfin, C, Monteagudo, J, Navas Elorza, E, Farinas Alvarez, M, Aguero Balbin, J, Zarauza, J, Gutierrez-Diez, J, Arminanzas, C, Arnaiz de las Revillas, F, Arnaiz Garcia, A, Cobo Belaustegui, M, Fernandez Sampedro, M, Gutierrez Cuadra, M, Garcia Cuello, L, Gonzalez Rico, C, Rodriguez-Alvarez, R, Goikoetxea, J, Montejo, M, Miro, J, Almela, M, Ambrosioni, J, Moreno, A, Quintana, E, Sandoval, E, Tellez, A, Tolosana, J, Vidal, B, Falces, C, Fuster, D, Garcia-de-la-Maria, C, Llopis, J, Marco, F, Ruiz-Zamora, I, Bardaji Ruiz, A, Sanz Girgas, E, Garcia-Pardo, G, Guillen Marzo, M, Rodriguez Oviedo, A, Villares Jimenez, A, Abid, L, Hammami, R, Kammoun, S, Mourali, M, Mghaieth Zghal, F, Ben Hlima, M, Boudiche, S, Ouali, S, Zakhama, L, Antit, S, Slama, I, Gulel, O, Sahin, M, Karacaglar, E, Kucukoglu, S, Cetinarslan, O, Sinan, U, Canpolat, U, Atas, H, Dervishova, R, Ileri, C, Alhashmi, J, Tahir, J, Zarger, P, Baslib, F, Woldman, S, Menezes, L, Primus, C, Uppal, R, Bvekerwa, I, Chandrasekaran, B, Kopanska, A, Chambers, J, Hancock, J, Klein, J, Rajani, R, Ursi, M, Cannata, S, Dworakowski, R, Fife, A, Breeze, J, Browne-Morgan, M, Gunning, M, Streather, S, Asch, F, Zemedkun, M, Alyavi, B, and Uzokov, J

Subjects
Male, Congestive heart failure, Survival, SURGERY, IMPACT, Hospital mortality, Infective endocarditi, Sağlık Bilimleri, Cardiovascular, Clinical Medicine (MED), Endocarditis, Bacterial/complications, PROGNOSTIC-FACTORS, KALP VE KALP DAMAR SİSTEMLERİ, [SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases, Early surgery, Klinik Tıp (MED), Prospective Studies, Registries, PREDICTORS, ComputingMilieux_MISCELLANEOUS, Outcome, RISK, [SDV.MHEP.ME]Life Sciences [q-bio]/Human health and pathology/Emerging diseases, Klinik Tıp, DEATH, Middle Aged, Tıp, Heart Failure/complications, [SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/Virology, Medicine, Female, EURO-ENDO, Cardiology and Cardiovascular Medicine, Kardiyoloji, Kardiyoloji ve Kardiyovasküler Tıp, NATIVE VALVE ENDOCARDITIS, [SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system, Endocarditis/complications, Health Sciences, Humans, [SDV.MP.PAR]Life Sciences [q-bio]/Microbiology and Parasitology/Parasitology, Retrospective Studies, Internal Medicine Sciences, MORTALITY, MED/11 - MALATTIE DELL'APPARATO CARDIOVASCOLARE, Dahili Tıp Bilimleri, ADULTS, Infective endocarditis, CLINICAL MEDICINE, [SDV.MP.BAC]Life Sciences [q-bio]/Microbiology and Parasitology/Bacteriology, CARDIAC & CARDIOVASCULAR SYSTEMS
Abstract

International audience; AIMS: To evaluate the current management and survival of patients with left-sided infective endocarditis (IE) complicated by congestive heart failure (CHF) in the ESC-EORP European Endocarditis (EURO-ENDO) registry. METHODS AND RESULTS: Among the 3116 patients enrolled in this prospective registry, 2449 (mean age: 60 years, 69% male) with left-sided (native or prosthetic) IE were included in this study. Patients with CHF (n~=~698, 28.5%) were older, with more comorbidity and more severe valvular damage (mitro-aortic involvement, vegetations >10\,mm and severe regurgitation/new prosthesis dehiscence) than those without CHF (all p\,≤q\,0.019). Patients with CHF experienced higher 30-day and 1-year mortality than those without (20.5% vs. 9.0% and 36.1% vs. 19.3%, respectively) and CHF remained strongly associated with 30-day (odds ratio[OR] 2.37, 95% confidence interval [CI] [1.73-3.24; p\,10\,mm, severe valvular regurgitation and/or new prosthetic dehiscence, perivalvular complication, and prosthetic IE (OR 0.22, 95% CI 0.12-0.38; p\

Published
2022

12. Socio-Economic Variations Determine the Clinical Presentation, Aetiology and Outcome of Infective Endocarditis: a Prospective Cohort Study from the ESC-EORP EURO-ENDO (European Infective Endocarditis) Registry

Author

Sengupta, Shantanu P, Prendergast, Bernard, Laroche, Cécile, Furnaz, Shumaila, Ronderos, Ricardo, Almaghraby, Abdallah, Asch, Federico M, Blechova, Kamila, Zaky, Hosam, Strahilevitz, Jacob, Dworakowski, Rafal, Miyasaka, Yoko, Sebag, Igal, Izumi, Chisato, Axler, Olivier, Jamiel, Abdulrahman, Philip, Mary, Campos Vieira, Marcelo Luiz, Lancellotti, Patrizio, Habib, Gilbert, P Gale, C, Beleslin, B, Budaj, A, Chioncel, O, Dagres, N, Danchin, N, Emberson, J, Erlinge, D, Glikson, M, Gray, A, Kayikcioglu, M, P Maggioni, A, K Nagy, V, Nedoshivin, A, A-S, Petronio, Roos-Hesselink, J, Wallentin, L, Zeymer, U, Habib, G, Lancellotti, P, Cosyns, B, Donal, E, Erba, P, Iung, B, A Popescu, B, Prendergast, B, Tornos, P, Andarala, M, Berle, C, Brunel-Lebecq, A, Fiorucci, E, Laroche, C, Missiamenou, V, Taylor, C, N Ali Tatar-Chentir, N, Al-Mallah, M, M Astrom Aneq, Athanassopoulos, G, P Badano, L, Benyoussef, S, E Calderon Aranda, M Cardim, N, K-L, Chan, Cruz, I, Edvardsen, T, Goliasch, G, Hagendorff, A, Hristova, K, Kamp, O, D-H, Kang, Kong, W, Matskeplishvili, S, Meshaal, M, Mirocevic, M, N Neskovic, A, Pazdernik, M, Plonska-Gosciniak, E, Raissouni, M, Ronderos, R, E Sade, L, Sadeghpour, A, Sambola, A, Sengupta, S, Separovic-Hanzevacki, J, Takeuchi, M, Tucay, E, C Tude Rodrigues, A, Varga, A, Vaskelyte, J, Yamagata, K, Yiangou, K, Zaky, H, Granada, I, Mahia, M, Ressi, S, Nacinovich, F, Iribarren, A, P Fernandez Oses, Avegliano, G, Filipini, E, Obregon, R, Bangher, M, Dho, J, Cartasegna, L, L Plastino, M, Novas, V, Shigel, C, Reyes, G, M De Santos, Gastaldello, N, M Granillo Fernandez, Potito, M, Streitenberger, G, Velazco, P, H Casabé, J, Cortes, C, Guevara, E, Salmo, F, Seijo, M, Weidinger, F, Heger, M, Brooks, R, Stöllberger, C, C-Y, Ho, Perschy, L, Puskas, L, Binder, C, Rosenhek, R, Schneider, M, M-P, Winter, Hoffer, E, Melissopoulou, M, Lecoq, E, Legrand, D, Jacquet, S, Massoz, M, Pierard, L, Marchetta, S, Dulgheru, R, D Emal, C, Oury, C, Droogmans, S, Kerkhove, D, Plein, D, 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C Castillo, J, L Zamorano, J, L Moya Mur, J, Alvaro, M, Fernandez-Golfin, C, M Monteagudo, J, E Navas Elorza, C Farinas Alvarez, M, J Aguero Balbin, Zarauza, J, F Gutierrez-Diez, J, Arminanzas, C, F Arnaiz de Las Revillas, A Arnaiz Garcia, M Cobo Belaustegui, M Fernandez Sampedro, M Gutierrez Cuadra, L Garcia Cuello, C Gonzalez Rico, Rodriguez-Alvarez, R, Goikoetxea, J, Montejo, M, M Miro, J, Almela, M, Ambrosioni, J, Moreno, A, Quintana, E, Sandoval, E, Tellez, A, M Tolosana, J, Vidal, B, Falces, C, Fuster, D, Garcia-de-la-Maria, C, Hernandez-Meneses, M, Llopis, J, Marco, F, Ruiz-Zamora, I, A Bardaji Ruiz, E Sanz Girgas, Garcia-Pardo, G, M Guillen Marzo, A Rodriguez Oviedo, A Villares Jimenez, Abid, L, Hammami, R, Kammoun, S, S Mourali, M, F Mghaieth Zghal, M Ben Hlima, Boudiche, S, Ouali, S, Zakhama, L, Antit, S, Slama, I, Gulel, O, Sahin, M, Karacaglar, E, Kucukoglu, S, Cetinarslan, O, S Yasar, U, Canpolat, U, Mutlu, B, Atas, H, Dervishova, R, Ileri, C, Alhashmi, J, Tahir, J, Zarger, P, Baslib, F, Woldman, S, Menezes, L, Primus, C, Uppal, R, Bvekerwa, I, Chandrasekaran, B, Kopanska, A, Chambers, J, Hancock, J, Klein, J, Rajani, R, P Ursi, M, Cannata, S, Dworakowski, R, Fife, A, Breeze, J, Browne-Morgan, M, Gunning, M, Streather, S, M Asch, F, Zemedkun, M, Alyavi, B, Uzokov, J, Microbes évolution phylogénie et infections (MEPHI), Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS), Département de Cardiologie [Hôpital de la Timone - APHM], Assistance Publique - Hôpitaux de Marseille (APHM)- Hôpital de la Timone [CHU - APHM] (TIMONE), CHU Pontchaillou [Rennes], ARN régulateurs bactériens et médecine (BRM), Université de Rennes (UR)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), 2011–21, Abbott Vascular, 2009–18, Amgen, 2016–19, Edwards, 2014–16, Gedeon Richter, 2009–12, Menarini Group, 2011–14, MSD, 2014–20, Novartis Pharma, 2014–16, ResMed Foundation, 2009–11, Sanofi, 2009–21, Servier, 2019–22, Vifor Pharma, 2014–21, AstraZeneca, 2009–18, Bayer AG, 2009–19, Boehringer Ingelheim, 2009–12, Boston Scientific, Bristol Myers Squibb, 2011–19, Pfizer Alliance, 2011–20, Daiichi Sankyo Company, 2014–17, Eli Lilly and Company, Sengupta, S, Prendergast, B, Laroche, C, Furnaz, S, Ronderos, R, Almaghraby, A, Asch, F, Blechova, K, Zaky, H, Strahilevitz, J, Dworakowski, R, Miyasaka, Y, Sebag, I, Izumi, C, Axler, O, Jamiel, A, Philip, M, Vieira, M, Lancellotti, P, Habib, G, Gale, C, Beleslin, B, Budaj, A, Chioncel, O, Dagres, N, Danchin, N, Emberson, J, Erlinge, D, Glikson, M, Gray, A, Kayikcioglu, M, Maggioni, A, Nagy, V, Nedoshivin, A, Petronio, A, Roos-Hesselink, J, Wallentin, L, Zeymer, U, Cosyns, B, Donal, E, Erba, P, Iung, B, Popescu, B, Tornos, P, Andarala, M, Berle, C, Brunel-Lebecq, A, Fiorucci, E, Missiamenou, V, Taylor, 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Brunel, A, Lim, P, Oliver, L, Ternacle, J, Moussafeur, A, Chavanet, P, Piroth, L, Salmon-Rousseau, A, Buisson, M, Mahy, S, Martins, C, Go-Hier, S, Baumann, F, Lebras, S, Piper, C, Guckel, D, Borgermann, J, Horstkotte, D, Winkelmann, E, Brockmeier, B, Grey, D, Nick-Enig, G, Schueler, R, Ozturk, C, Stohr, E, Hamm, C, Walther, T, Brandt, R, Fruhauf, A, Hartung, C, Hellner, C, Wild, C, Becker, M, Hamada, S, Kaestner, W, Stangl, K, Knebel, F, Baldenhofer, G, Brecht, A, Dreger, H, Isner, C, Pfafflin, F, Stegemann, M, Zahn, R, Fraiture, B, Kilkowski, C, Karcher, A, Klinger, S, Tolksdorf, H, Tousoulis, D, Aggeli, C, Sideris, S, Venieri, E, Sarri, G, Tsiapras, D, Armenis, I, Koutsiari, A, Floros, G, Grassos, C, Dragasis, S, Rallidis, L, Varlamos, C, Michalis, L, Naka, K, Bechlioulis, A, Kotsia, A, Lakkas, L, Pappas, K, Papadopoulos, C, Kiokas, S, Lioni, A, Misailidou, S, Bar-Betseas, J, Bonou, M, Kapelios, C, Tomprou, I, Zerva, K, Manolis, A, Hamodraka, E, Athanasiou, D, Haralambidis, G, Samaras, H, Poulimenos, L, Nagy, A, Bartykowszki, A, Gara, E, Mungulmare, K, Kasliwal, R, Bansal, M, Ranjan, S, Bhan, A, Kyavar, M, Maleki, M, Noohi Bezanjani, F, Alizadehasl, A, Boudagh, S, Ghavidel, A, Morad-Nejad, P, Pasha, H, Ghadrdoost, B, Gilon, D, Wanounou, M, Israel, S, D'Agostino, C, Colonna, P, De Michele, L, Fumarola, F, Stante, M, Mar-Chionni, N, Scheggi, V, Alterini, B, Del Pace, S, Stefano, P, Sparano, C, Ruozi, N, Tenaglia, R, Muraru, D, Limbruno, U, Cresti, A, Baratta, P, Solari, M, Giannattasio, C, Moreo, A, De Chiara, B, Lopez Montero, B, Musca, F, Orcese, C, Panzeri, F, Spano, F, Russo, C, Alferi, O, De Bonis, M, Chiappetta, S, Del Forno, B, Ripa, M, Scarpellini, P, Tassan Din, C, Castiglioni, B, Pasci-Uta, R, Carletti, S, Ferrara, D, Guffanti, M, Iaci, G, Lapenna, E, Nisi, T, Oltolini, C, Busnardo, E, Pajoro, U, Agricola, E, Meneghin, R, Schiavi, D, Piscione, F, Citro, R, Benvenga, R, Greco, L, Soriente, L, Radano, I, Prota, C, Bellino, M, Di Vece, D, Santini, F, 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Zvirblyte, R, Sow, R, Codreanu, A, Staub, T, Michaux, C, De la Vega, E, Jacobs-Orazi, L, Mallia Azzopardi, C, Xuereb, R, Pis-Copo, T, Farrugia, J, Fenech, M, Pllaha, E, Vella, C, Borg, D, Casha, R, Grib, L, Raevschi, E, Gre-Jdieru, A, Kravcenco, D, Prisacari, E, Samohvalov, E, Samohvalov, S, Sceglova, N, Panfle, E, Cardaniuc, L, Corcea, V, Feodorovici, A, Gaina, V, Girbu, L, Jimbei, P, Balan, G, Cardaniuc, I, Benesco, I, Marian, V, Sumarga, N, Bozovic, B, Bulatovic, N, Lakovic, P, Music, L, Budde, R, Waha-Dat, A, Gamela, T, Meijers, T, Van Melle, J, Deursen, V, Crijns, H, Bekkers, S, Cheriex, E, Gilbers, M, Kietselaer, B, Knackstedt, C, Lorusso, R, Schalla, S, Streukens, S, Chamuleau, S, Cramer, M, Teske, A, Van der Spoel, T, Wind, A, Lokhorst, J, Liesbek, O, Van Heusden, H, Tanis, W, Van der Bilt, I, Vriend, J, De Lange-Van Bruggen, H, Karijodikoro, E, Riezebos, R, van Dongen, E, Schoep, J, Stolk, V, Offstad, J, Beitnes, J, Helle-Valle, T, Skulstad, H, Skardal, R, Qamar, N, Ahmed, B, Butt, M, Khanzada, M, Saghir, T, Wahid, A, Hryniewiecki, T, Szymanski, P, Marzec, K, Misztal-Ogonowska, M, Kosmala, W, Przewlocka-Kosmala, M, Rojek, A, Woznicka, K, Zachwyc, J, Lisowska, A, Kamin-Ska, M, Kasprzak, J, Kowalczyk, E, Strzecka, D, Wejner-Mik, P, Trabulo, M, Freitas, P, Ranchordas, S, Rodrigues, G, Pinto, P, Queiros, C, Azevedo, J, Marques, L, Seabra, D, Branco, L, Cruz, M, Galrinho, A, Moreira, R, Rio, P, Timoteo, A, Selas, M, Carmelo, V, Duque Neves, B, Pereira, H, Guerra, A, Marques, A, Pintassilgo, I, Tomescu, M, Trofenciuc, N, Andor, M, Bordejevic, A, Branea, H, Caruntu, F, Velcean, L, Mavrea, A, Onel, M, Parvanescu, T, Pop, D, Pop-Moldovan, A, Puticiu, M, Cirin, L, Citu, I, Cotoraci, C, Darabantiu, D, Farcas, R, Marincu, I, Ionac, A, Cozma, D, Mornos, C, Goanta, F, Popescu, I, Beyer, R, Mada, R, Rancea, R, Tomoaia, R, Rosianu, H, Stanescu, C, Kobalava, Z, Karaulova, J, Ko-Tova, E, Milto, A, Pisaryuk, A, Povalyaev, N, Sorokina, M, Alrahimi, J, Elshiekh, A, Ahmed, A, Attia, N, Putnikovic, B, Dimic, A, Ivanovic, B, Matic, S, Trifunovic, D, Petrovic, J, Kosevic, D, Stojanovic, I, Petrovic, I, Dabic, P, Milojevic, P, Srdanovic, I, Susak, S, Velicki, L, Vulin, A, Kovacevic, M, Redzek, A, Stefanovic, M, Yeo, T, Poh, K, Vi-Lacosta, I, Ferrera, C, Olmos, C, Abd El-Nasser, M, Calvo Iglesias, F, Bianco-Gonzalez, E, Bravo Amaro, M, Lopez-Rodriguez, E, Lugo Adan, J, Germinas, A, Pazos-Lopez, P, Pereira Loureiro, M, Perez, M, Raposeiras-Roubin, S, Rasheed Yas, S, Suarez-Varela, M, Vasallo Vidal, F, Garcia-Dorado, D, Fernandez-Hidalgo, N, Gonzalez-Alujas, T, Lozano, J, Maisterra, O, Pizzi, N, Rios, R, Bayes-Genis, A, Pedro Botet, L, Vallejo, N, Llibre, C, Mateu, L, Nunez, R, Quesada, D, Berastegui, E, Bosch Portell, D, Aboal Vinas, J, Albert Bertran, X, Brugada Tar-Radellas, R, Loma-Osorio Ricon, P, Tiron de Llano, C, Arnau, M, Bel, A, Blanes, M, Osa, A, Anguita, M, Carrasco, F, Castillo, J, Zamorano, J, Moya Mur, J, Alvaro, M, Fernandez-Golfin, C, Monteagudo, 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Chandrasekaran, B, Kopanska, A, Chambers, J, Hancock, J, Klein, J, Rajani, R, Ursi, M, Cannata, S, Fife, A, Breeze, J, Browne-Morgan, M, Gunning, M, Streather, S, Zemedkun, M, Alyavi, B, and Uzokov, J

Subjects
Socioeconomic, [SDV.MHEP.ME]Life Sciences [q-bio]/Human health and pathology/Emerging diseases, Endocarditis, [SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system, [SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases, Health Policy, [SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/Virology, Socio-economic, [SDV.MP.PAR]Life Sciences [q-bio]/Microbiology and Parasitology/Parasitology, Endocarditi, Cardiology and Cardiovascular Medicine, [SDV.MP.BAC]Life Sciences [q-bio]/Microbiology and Parasitology/Bacteriology
Abstract

Aims Infective endocarditis (IE) is a life-threatening disease associated with high mortality and morbidity worldwide. We sought to determine how socioeconomic factors might influence its epidemiology, clinical presentation, investigation and management, and outcome, in a large international multicentre registry. Methods and results The EurObservational Programme (EORP) of the European Society of Cardiology EURO-ENDO (European Infective Endocarditis) registry comprises a prospective cohort of 3113 adult patients admitted for IE in 156 hospitals in 40 countries between January 2016 and March 2018. Patients were separated in three groups, according to World Bank economic stratification [group 1: high income (75.6%); group 2: upper-middle income (15.4%); group 3: lower-middle income (9.1%)]. Group 3 patients were younger [median age (interquartile range, IQR): group 1, 66 (53–75) years; group 2, 57 (41–68) years; group 3, 33 (26–43) years; P < 0.001] with a higher frequency of smokers, intravenous drug use, and human immunodeficiency virus infection (all P < 0.001) and presented later [median (IQR) days since symptom onset: group 1, 12 (3–35); group 2, 19 (6–54); group 3, 31 (12–62); P < 0.001] with a higher likelihood of developing congestive heart failure (13.6%, 11.1%, and 22.6%, respectively; P < 0.001) and persistent fever (9.8%, 14.2%, and 27.9%, respectively; P < 0.001). Among 2157 (69.3%) patients with theoretical indication for cardiac surgery, surgery was performed less frequently in group 3 patients (75.5%, 76.8%, and 51.3%, respectively; P < 0.001), who also demonstrated the highest mortality (15.0%, 23.0%, and 23.7%, respectively; P < 0.001). Conclusion Socioeconomic factors influence the clinical profile of patients presenting with IE across the world. Despite younger age, patients from the poorest countries presented with more frequent complications and higher mortality associated with delayed diagnosis and lower use of surgery.

Published
2022

13. Correction to: Surgery and outcome of infective endocarditis in octogenarians: prospective data from the ESC EORP EURO-ENDO registry (Infection, (2022), 50, 5, (1191-1202), 10.1007/s15010-022-01792-0)

Author

Pazdernik, Michal, Iung, Bernard, Mutlu, Bulent, Alla, François, Riezebos, Robert, Kong, William, Nunes, Maria Carmo Pereira, Pierard, Luc, Srdanovic, Ilija, Yamada, Hirotsugu, de Martino, Andrea, Miglioranza, Marcelo Haertel, Magne, Julien, Piper, Cornelia, Laroche, C. cile, Maggioni, Aldo P., Lancellotti, Patrizio, Habib, Gilbert, Selton-Suty, Christine, Ronderos, R., Avegliano, G., Oses, P. Fernandez, Filipini, E., Granada, I., Iribarren, A., Mahia, M., Nacinovich, F., Ressi, S., Obregon, R., Bangher, M., Dho, J., Cartasegna, L., Plastino, M. L., Novas, V., Shigel, C., Reyes, G., de Santos, M., Gastaldello, N., Fernandez, M. Granillo, Potito, M., Streitenberger, G., Velazco, P., Casabé, J. H., Cortes, C., Guevara, E., Salmo, F., Seijo, M., Weidinger, F., Heger, M., Brooks, R., Stöllberger, C., Ho, C. Y., Perschy, L., Puskas, L., Goliasch, G., Binder, C., Rosenhek, R., Schneider, M., Winter, M. P., Hoffer, E., Melissopoulou, M., Lecoq, E., Legrand, D., Jacquet, S., Massoz, M., Lancellotti, P., Pierard, L., Dulgheru, R., Marchetta, S., D´Emal, C., Oury, C., Cosyns, B., Droogmans, S., Kerkhove, D., Motoc, A., Plein, D., Roosens, B., Soens, L., Weytjens, C., Lemoine, I., Rodrigus, I., Paelinck, B., Amsel, B., Unger, P., Konopnicki, D., Beauloye, C., Pasquet, A., Pierard, S., Vancraeynest, D., Vanoverschelde, J. L., Sinnaeve, F., Andrade, J. L., Rodrigues, A. C. Tude, Staszko, K., Dos Santos Monteiro, R., Miglioranza, M. H., Shuha, D. L., Alcantara, M., Cravo, V., Fazzio, L., Felix, A., Iso, M., Musa, C., Siciliano, A. P., Filho, F. Villaca, Braga, J., Rodrigues, A., Silva, R., Vilela, F., Rodrigues, D., Silva, L., Morhy, S., Fischer, C., Vieira, M., Afonso, T., Abreu, J., Falcao, S. N., Moises, V., Gouvea, A., João, G., Mancuso, F., Silva, C., Souza, A. C., Abboud, C. S., de Mattos Barretto, R. Bellio, Ramos, A., Arnoni, R., Assef, J. E., Togna, D. J. Della, le Bihan, D., Miglioli, L., Oliveira, A. P. Romero, Kroll, R. Tadeu Magro, Cortez, D., Gelape, C. L., Nunes, M. d. C. Peirira, de Abreu Ferrari, T. C., Chan, K. L., Hay, K., le, V., Page, M., Poulin, F., Sauve, C., Serri, K., Mercure, C., Beaudoin, J., Pibarot, P., Sebag, I., Rudski, L., Ricafort, G., Barsic, B., Krajinovic, V., Vargovic, M., Separovic-Hanzevacki, J., Lovric, D., Reskovic-Luksic, V., Vincelj, J., Jurinjak, S. Jaksic, Yiannikourides, V., Ioannides, M., Kyriakou, C., Pofaides, C., Masoura, V., Yiangou, K., Pudich, J., Linhart, A., Siranec, M., Marek, J., Blechova, K., Kamenik, M., Pazdernik, M., Pelouch, R., Coufal, Z., Mikulica, M., Griva, M., Jancova, E., Mikulcova, M., Taborsky, M., Precek, J., Jecmenova, M., Latal, J., Widimsky, J., Butta, T., Machacek, S., Vancata, R., Spinar, J., Holicka, M., Long, F. Pow Chon, Anzules, N., Carpio, A. Bajana, Largacha, G., Penaherrera, E., Moreira, D., Mahfouz, E., Elsafty, E., Soliman, A., Zayed, Y., Aboulenein, J., Abdel-Hay, M., Almaghraby, A., Abdelnaby, M., Ahmed, M., Hammad, B., Saleh, Y., Zahran, H., Elgebaly, O., Saad, A., Ali, M., Zeid, A., Sharkawy, R. El, Meshaal, M., Al Kholy, A., Doss, R., Osama, D., Rizk, H., Elmogy, A., Mishriky, M., Assayag, P., Hatimi, S. El, Botelho-Nevers, Saint- E., Campisi, S., Fuzellier, J. F., Gagneux-Brunon, A., Pierrard, R., Tulane, C., Detoc, M., Mehalla, T., Boutoille, D., Al Habash, O., Asseray-Madani, N., Biron, C., Brochard, J., Caillon, J., Cueff, C., le Tourneau, T., Lecompte, A. S., Lecomte, R., Lefebvre, M., Michel, M. M. Magali, Pattier, S., Delarue, S., le Bras, M., Orain, J., Faucher, J. F., Aboyans, V., Beeharry, A., Durox, H., Lacoste, M., Magne, J., Mohty, D., David, A., Pradel, V., Sierra, V., Neykova, A., Bettayeb, B., Elkentaoui, S., Tzvetkov, B., Landry, G., Strady, C., Ainine, K., Baumard, S., Brasselet, C., Tassigny, C., Valente-Pires, V., Lefranc, M., Hoen, B., Lefevre, B., Curlier, E., Callier, C., Fourcade, N., Jobic, Y., Ansard, S., le Berre, R., le Roux, P., le Ven, F., Pouliquen, M. C., Prat, G., Bouchart, F., Savoure, A., Alarcon, C., Chapuzet, C., Gueit, I., Tribouilloy, C., Bohbot, Y., Peugnet, F., Gun, M., Iung, B., Duval, X., Lescure, X., Ilic-Habensus, E., Sadoul, N., Selton-Suty, C., Alla, F., Chevalier, E., Goehringer, F., Huttin, O., Garcia, R., le Marcis, V., Tattevin, P., Donal, E., Flecher, E., Revest, M., Habib, G., Hubert, S., Casalta, J. P., Gouriet, F., Arregle, F., Cammilleri, S., Tessonnier, L., Riberi, A., Chirouze, C., Bouiller, K., Brunel, A. S., Fournier, D., Hustache-Mathieu, L., Klopfenstein, T., Moreau, J., Lim, P., Oliver, L., Ternacle, J., Moussafeur, A., Chavanet, P., Piroth, L., Buisson, M., Mahy, S., Martins, C., Salmon-Rousseau, A., Gohier, S., Piper, C., Börgermann, J., Guckel, D., Horstkotte, D., Brockmeier, B., Winkelmann, E., Hagendorff, A., Grey, D., Nickenig, G., Schueler, R., Öztürk, C., Stöhr, E., Hamm, C., Walther, T., Brandt, R., Frühauf, A. C., Hartung, C. T., Hellner, C., Wild, C., Becker, M., Hamada, S., Kaestner, W., Stangl, K., Knebel, F., Baldenhofer, G., Brecht, A., Dreger, H., Isner, C., Pfafflin, F., Stegemann, M., Zahn, R., Fraiture, B., Kilkowski, C., Karcher, A. K., Klinger, S., Tolksdorf, H., Tousoulis, D., Aggeli, C., Sarri, G., Sideris, S., Venieri, E., Athanassopoulos, G., Tsiapras, D., Armenis, I., Koutsiari, A., Floros, G., Grassos, C., Dragasis, S., Rallidis, L., Varlamos, C., Michalis, L., Naka, K., Bechlioulis, A., Kotsia, A., Lakkas, L., Pappas, K., Papadopoulos, C., Kiokas, S., Lioni, A., Misailidou, S., Barbetseas, J., Bonou, M., Kapelios, C., Tomprou, I., Zerva, K., Manolis, A., Hamodraka, E., Athanasiou, D., Haralambidis, G., Poulimenos, L., Samaras, H., Nagy, A., Bartykowszki, A., Gara, E., Sengupta, S., Mungulmare, K., Kasliwal, R., Bansal, M., Bhan, A., Ranjan, S., Kyavar, M., Maleki, M., Bezanjani, F. Noohi, Sadeghpour, A., Alizadehasl, A., Boudagh, S., Ghavidel, A., Moradnejad, P., Pasha, H. 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H., Heo, R., Lee, S., Song, J. M., Jung, E., Plisiene, J., Dambrauskaite, A., Gruodyte, G., Jonkaitiene, R., Vaskelyte, J., Mizariene, V., Atkocaityte, J., Zvirblyte, R., Sow, R., Codreanu, A., de la Vega, E. C. L., Michaux, C., Staub, T., Jacobs-Orazi, L., Azzopardi, C. Mallia, Xuereb, R. G., Piscopo, T., Borg, D., Casha, R., Farrugia, J., Fenech, M., Pllaha, E., Vella, C., Yamagata, K., Grib, L., Raevschi, E., Grejdieru, A., Balan, G., Cardaniuc, I., Cardaniuc, L., Corcea, V., Feodorovici, A., Gaina, V., Girbu, L., Jimbei, P., Kravcenco, D., Panfile, E., Prisacari, E., Samohvalov, E., Samohvalov, S., Sceglova, N., Benesco, I., Marian, V., Sumarga, N., Mirocevic, M., Bozovic, B., Bulatovic, N., Lakovic, P., Music, L., Roos-Hesselink, J., Budde, R., Gamela, T., Wahadat, A., Kamp, O., Meijers, T., van Melle, J. P., Deursen, V. M., Crijns, H., Bekkers, S., Cheriex, E., Gilbers, M., Kietselaer, B., Knackstedt, C., Lorusso, R., Schalla, S., Streukens, S., Chamuleau, S., Cramer, M. J., Teske, A., van der Spoel, T., Wind, A., Liesbek, O., Lokhorst, J., van Heusden, H., Tanis, W., van der Bilt, I., Vriend, J., de Lange-van Bruggen, H., Karijodikoro, E., Riezebos, R., van Dongen, E., Schoep, J., Stolk, V., Axler, O., Baumann, F., Lebras, S., Edvardsen, T., Offstad, J. T., Beitnes, J. O., Helle-Valle, T., Skulstad, H., Skardal, R., Qamar, N., Furnaz, S., Ahmed, B., Butt, M. H., Khanzada, M. F., Saghir, T., Wahid, A., Hryniewiecki, T., Szymanski, P., Marzec, K., Misztal-Ogonowska, M., Kosmala, W., Przewlocka-Kosmala, M., Rojek, A., Woznicka, K., Zachwyc, J., Lisowska, A., Kaminska, M., Kasprzak, J., Kowalczyk, E., Strzecka, D. F., Wejner-Mik, P., Trabulo, M., Freitas, P., Ranchordas, S., Rodrigues, G., Pinto, P., Queiros, C., Azevedo, J., Marques, L., Seabra, D., Branco, L., Cruz, M., Galrinho, A., Moreira, R., Rio, P., Timoteo, A. T., Selas, M., Cardim, N. M., Carmelo, V., Neves, B. Duque, Pereira, H., Cruz, I., Guerra, A., Marques, A., Pintassilgo, I., Tomescu, M. C., Trofenciuc, N. M., Andor, M., Bordejevic, A., Branea, H. S., Caruntu, F., Cirin, L., Citu, I. M., Cotoraci, C. A., Darabantiu, D., Farcas, R., Marincu, I., Mavrea, A., Onel, M. F., Parvanescu, T., Pop, D., Pop-Moldovan, A. L., Puticiu, M. I., Velcean, L. A., Ionac, A., Cozma, D., Mornos, C., Goanta, F., Popescu, I., Beyer, R., Mada, R., Rancea, R., Rosianu, H., Tomoaia, R., Stanescu, C., Kobalava, Z., Karaulova, J., Kotova, E., Milto, A., Pisaryuk, A., Povalyaev, N., Sorokina, M., Alrahimi, J., Elshiekh, A., Jamiel, A., Ahmed, A., Al-Mallah, M., Attia, N., Putnikovic, B., Neskovic, A., Dimic, A., Ivanovic, B., Matic, S., Trifunovic, D., Petrovic, J., Kosevic, D., Dabic, P., Milojevic, P., Petrovic, I., Stojanovic, I., Srdanovic, I., Kovacevic, M., Redzek, A., Stefanovic, M., Susak, S., Velicki, L., Vulin, A., Yeo, T. C., Kong, W. K. F., Poh, K. K., Vilacosta, I., Nasser, M. Abd El, Ferrera, C., Olmos, C., Iglesias, F. Calvo, Blanco-Gonzalez, E., Amaro, M. Bravo, Germinas, A. 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Abstract

In this article the “EURO-ENDO Investigators group” member U. Y. Sinan was incorrectly written as U.S. Yasar. The original article has been corrected.

Published
2022

14. 944P Hazard function analysis of recurrence in patients with curatively resected lung cancer: Results from the Japanese Lung Cancer Registry in 2010

Author

Yamauchi, Y., primary, Kawamura, M., additional, Okami, J., additional, Shintani, Y., additional, Ito, H., additional, Ohtsuka, T., additional, Toyooka, S., additional, Mori, T., additional, Watanabe, S-I., additional, Asamura, H., additional, Chida, M., additional, Endo, S., additional, Kadokura, M., additional, Nakanishi, R., additional, Miyaoka, E., additional, Yoshino, I., additional, and Date, H., additional

Published
2022
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15. The ESC-EORP EURO-ENDO (European Infective Endocarditis) registry

Author

Habib G., Lancellotti P., Erba P. -A., Sadeghpour A., Meshaal M., Sambola A., Furnaz S., Citro R., Ternacle J., Donal E., Cosyns B., Popescu B., Iung B., Prendergast B., Laroche C., Tornos P., Pazdernik M., Maggioni A., Gale C. P., Ali Tatar-Chentir N. N., Al-Mallah M., Astrom Aneq M., Athanassopoulos G., Badano L, Benyoussef S., Calderon Aranda E., Cardim N. M., Chan K. -L., Cruz I., Edvardsen T., Goliasch G., Hagendorff A., Hristova K., Kamp O., Kang D. -H., Kong W., Matskeplishvili S., Mirocevic M., Neskovic A. N., Plonska-Gosciniak E., Popescu B. A., Raissouni M., Ronderos R., Sade L. E., Sengupta S., Separovic-Hanzevacki J., Takeuchi M., Tucay E., Tude Rodrigues A. C., Varga A., Vaskelyte J., Yamagata K., Yiangou K., Zaky H., Granada I., Mahia M., Ressi S., Nacinovich F., Iribarren A., Fernandez Oses P., Avegliano G., Filipini E., Obregon R., Bangher M., Dho J., Cartasegna L., Plastino M. L., Novas V., Shigel C., Reyes G., De Santos M., Gastaldello N., Granillo Fernandez M., Potito M., Streitenberger G., Velazco P., Casabe J. H., Cortes C., Guevara E., Salmo F., Seijo M., Weidinger F., Heger M., Brooks R., Stollberger C., Ho C. -Y., Perschy L., Puskas L., Binder C., Rosenhek R., Schneider M., Winter M. -P., Hoffer E., Melissopoulou M., Lecoq E., Legrand D., Jacquet S., Massoz M., Pierard L., Marchetta S., Dulgheru R., Emal C. D., Oury C., Droogmans S., Kerkhove D., Plein D., Soens L., Weytjens C., Motoc A., Roosens B., Lemoine I., Rodrigus I., Paelinck B., Amsel B., Unger P., Konopnicki D., Beauloye C., Pasquet A., Vanoverschelde J. L., Pierard S., Vancraeynest D., Sinnaeve F., Andrade J. L., Staszko K., Dos Santos Monteiro R., Miglioranza M. H., Shuha D. L., Alcantara M., Cravo V., Fazzio L., Felix A., Iso M., Musa C., Siciliano A. P., Villaca Filho F., Rodrigues A., Vilela F., Braga J., Silva R., Rodrigues D., Silva L., Morhy S., Fischer C., Vieira M., Afonso T., Abreu J., Falcao S. N., Moises V. A., Gouvea A., Mancuso F. J., Souza A. C., Silva C. Y., Joao G., Abboud C. S., Bellio De Mattos Barretto R., Ramos A., Arnoni R., Assef J. E., Della Togna D. J., Bihan D. L., Miglioli L., Romero Oliveira A. P., Tadeu Magro Kroll R., Cortez D., Gelape C. L., Peirira Nunes M. D. C., De Abreu Ferrari T. C., Hay K., Le V., Page M., Poulin F., Sauve C., Serri K., Mercure C., Beaudoin J., Pibarot P., Sebag I. A., Rudski L. G., Ricafort G., Barsic B., Krajinovic V., Vargovic M., Lovric D., Reskovic-Luksic V., Vincelj J., Jaksic Jurinjak S., Yiannikourides V., Ioannides M., Pofaides C., Masoura V., Pudich J., Linhart A., Siranec M., Marek J., Blechova K., Kamenik M., Pelouch R., Coufal Z., Mikulica M., Griva M., Jancova E., Mikulcova M., Taborsky M., Precek J., Jecmenova M., Latal J., Widimsky J., Butta T., MacHacek S., Vancata R., Spinar J., Holicka M., Pow Chon Long F., Anzules N., Bajana Carpio A., Largacha G., Penaherrera E., Moreira D., Mahfouz E., Elsafty E., Soliman A., Zayed Y., Aboulenein J., Abdel-Hay M., Almaghraby A., Abdelnaby M., Ahmed M., Hammad B., Saleh Y., Zahran H., Elgebaly O., Saad A., Ali M., Zeid A., El Sharkawy R., Al Kholy A., Doss R., Osama D., Rizk H., Elmogy A., Mishriky M., Assayag P., El Hatimi S., Hubert S., Casalta J. -P., Gouriet F., Arregle F., Cammilleri S., Tessonnier L., Riberi A., Botelho-Nevers E., Gagneux-Brunon A., Pierrard R., Tulane C., Campisi S., Fuzellier J. -F., Detoc M., Mehalla T., Boutoille D., Lecompte A. S., Lefebvre M., Pattier S., Al Habash O., Asseray-Madani N., Biron C., Brochard J., Caillon J., Cueff C., Tourneau T. L., Lecomte R., Magali Michel M. M., Orain J., Delarue S., Bras M. L., Faucher J. -F., Aboyans V., Beeharry A., Durox H., Lacoste M., Magne J., Mohty D., David A., Pradel V., Sierra V., Neykova A., Bettayeb B., Elkentaoui S., Tzvetkov B., Landry G., Strady C., Ainine K., Baumard S., Brasselet C., Tassigny C., Valente-Pires V., Lefranc M., Hoen B., Lefevre B., Curlier E., Callier C., Fourcade N., Jobic Y., Ansard S., Berre R. L., Ven F. L., Pouliquen M. -C., Prat G., Roux P. L., Bouchart F., Savoure A., Alarcon C., Chapuzet C., Gueit I., Tribouilloy C., Bohbot Y., Peugnet F., Gun M., Duval X., Lescure X., Ilic-Habensus E., Sadoul N., Selton-Suty C., Alla F., Goehringer F., Huttin O., Chevalier E., Garcia R., Marcis V. L., Tattevin P., Flecher E., Revest M., Chirouze C., Bouiller K., Hustache-Mathieu L., Klopfenstein T., Moreau J., Fournier D., Brunel A. -S., Lim P., Oliver L., Moussafeur A., Chavanet P., Piroth L., Salmon-Rousseau A., Buisson M., Mahy S., Martins C., Gohier S., Axler O., Baumann F., Lebras S., Piper C., Guckel D., Borgermann J., Horstkotte D., Winkelmann E., Brockmeier B., Grey D., Nickenig G., Schueler R., Ozturk C., Stohr E., Hamm C., Walther T., Brandt R., Fruhauf A. -C., Hartung C. T., Hellner C., Wild C., Becker M., Hamada S., Kaestner W., Stangl K., Knebel F., Baldenhofer G., Brecht A., Dreger H., Isner C., Pfafflin F., Stegemann M., Zahn R., Fraiture B., Kilkowski C., Karcher A. -K., Klinger S., Tolksdorf H., Tousoulis D., Aggeli C., Sideris S., Venieri E., Sarri G., Tsiapras D., Armenis I., Koutsiari A., Floros G., Grassos C., Dragasis S., Rallidis L., Varlamos C., Michalis L., Naka K., Bechlioulis A., Kotsia A., Lakkas L., Pappas K., Papadopoulos C., Kiokas S., Lioni A., Misailidou S., Barbetseas J., Bonou M., Kapelios C., Tomprou I., Zerva K., Manolis A., Hamodraka E., Athanasiou D., Haralambidis G., Samaras H., Poulimenos L., Nagy A., Bartykowszki A., Gara E., Mungulmare K., Kasliwal R., Bansal M., Ranjan S., Bhan A., Kyavar M., Maleki M., Noohi Bezanjani F., Alizadehasl A., Boudagh S., Ghavidel A., Moradnejad P., Pasha H. R., Ghadrdoost B., Gilon D., Strahilevitz J., Wanounou M., Israel S., D'Agostino C., Colonna P., Michele L. D., Fumarola F., Stante M., Marchionni N., Scheggi V., Alterini B., Del Pace S., Stefano P., Sparano C., Ruozi N., Tenaglia R., Muraru D., Limbruno U., Cresti A., Baratta P., Solari M., Giannattasio C., Moreo A., Chiara B. D., Lopez Montero B., Musca F., Orcese C. A., Panzeri F., Spano F., Russo C. F., Alfieri O., Bonis M. D., Chiappetta S., Del Forno B., Ripa M., Scarpellini P., Tassan Din C., Castiglioni B., Pasciuta R., Carletti S., Ferrara D., Guffanti M., Iaci G., Lapenna E., Nisi T., Oltolini C., Busnardo E., Pajoro U., Agricola E., Meneghin R., Schiavi D., Piscione F., Benvenga R. M., Greco L., Soriente L., Radano I., Prota C., Bellino M., Vece D. D., Santini F., Salsano A., Olivieri G. M., Turrini F., Messora R., Tondi S., Olaru A., Agnoletto V., Grassi L., Leonardi C., Sansoni S., Del Ponte S., Actis Dato G. M., Martino A. D., Ohte N., Kikuchi S., Wakami K., Aonuma K., Seo Y., Ishizu T., MacHino-Ohtsuka T., Yamamoto M., Iida N., Nakajima H., Nakagawa Y., Izumi C., Amano M., Miyake M., Takahashi K., Shiojima I., Miyasaka Y., Maeba H., Suwa Y., Taniguchi N., Tsujimoto S., Kitai T., Ota M., Yuda S., Sasaki S., Hagiwara N., Yamazaki K., Ashihara K., Arai K., Saitou C., Saitou S., Suzuki G., Shibata Y., Watanabe N., Nishino S., Ashikaga K., Kuriyama N., Mahara K., Okubo T., Fujimaki H., Shitan H., Yamamoto H., Abe K., Terada M., Takanashi S., Sata M., Yamada H., Kusunose K., Saijo Y., Seno H., Yuichiro O., Onishi T., Sera F., Nakatani S., Mizuno H., Sengoku K., Park S. W., Eun Kyoung K., Ga Yeon L., Hwang J. -W., Jin-Oh C., Park S. -J., Sang-Chol L., Sung-A C., Jang S. Y., Heo R., Lee S., Song J. -M., Jung E., Plisiene J., Dambrauskaite A., Gruodyte G., Jonkaitiene R., Mizariene V., Atkocaityte J., Zvirblyte R., Sow R., Codreanu A., Staub T., Michaux C., De La Vega E. C. L., Jacobs-Orazi L., Mallia Azzopardi C., Xuereb R. G., Piscopo T., Farrugia J., Fenech M., Pllaha E., Vella C., Borg D., Casha R., Grib L., Raevschi E., Grejdieru A., Kravcenco D., Prisacari E., Samohvalov E., Samohvalov S., Sceglova N., Panfile E., Cardaniuc L., Corcea V., Feodorovici A., Gaina V., Girbu L., Jimbei P., Balan G., Cardaniuc I., Benesco I., Marian V., Sumarga N., Bozovic B., Bulatovic N., Lakovic P., Music L., Budde R., Wahadat A., Gamela T., Meijers T., Van Melle J. P., Deursen V. M., Crijns H. J., Bekkers S. C., Cheriex E. C., Gilbers M., Kietselaer B. L., Knackstedt C., Lorusso R., Schalla S., Streukens S. A., Chamuleau S., Cramer M. -J., Teske A., Van Der Spoel T., Wind A., Lokhorst J., Liesbek O., Van Heusden H., Tanis W., Van Der Bilt I., Vriend J., Lange-Van Bruggen H. D., Karijodikoro E., Riezebos R., Van Dongen E., Schoep J., Stolk V., Offstad J. T., Beitnes J. O., Helle-Valle T., Skulstad H., Skardal R., Qamar N., Ahmed B., Butt M. H., Khanzada M. F., Saghir T., Wahid A., Hryniewiecki T., Szymanski P., Marzec K., Misztal-Ogonowska M., Kosmala W., Przewlocka-Kosmala M., Rojek A., Woznicka K., Zachwyc J., Lisowska A., Kaminska M., Kasprzak J. D., Kowalczyk E., Strzecka D. F., Wejner-Mik P., Trabulo M., Freitas P., Ranchordas S., Rodrigues G., Pinto P., Queiros C., Azevedo J., Marques L., Seabra D., Branco L., Cruz M., Galrinho A., Moreira R., Rio P., Timoteo A. T., Selas M., Carmelo V., Duque Neves B., Pereira H., Guerra A., Marques A., Pintassilgo I., Tomescu M. C., Trofenciuc N. -M., Andor M., Bordejevic A., Branea H. S., Caruntu F., Velcean L. A., Mavrea A., Onel M. F., Parvanescu T., Pop D., Pop-Moldovan A. L., Puticiu M. I., Cirin L., Citu I. M., Cotoraci C. A., Darabantiu D., Farcas R., Marincu I., Ionac A., Cozma D., Mornos C., Goanta F., Popescu I., Beyer R., Mada R., Rancea R., Tomoaia R., Rosianu H., Stanescu C., Kobalava Z., Karaulova J., Kotova E., Milto A., Pisaryuk A., Povalyaev N., Sorokina M., Alrahimi J., Elshiekh A., Jamiel A., Ahmed A., Attia N., Putnikovic B., Dimic A., Ivanovic B., Matic S., Trifunovic D., Petrovic J., Kosevic D., Stojanovic I., Petrovic I., Dabic P., Milojevic P., Srdanovic I., Susak S., Velicki L., Vulin A., Kovacevic M., Redzek A., Stefanovic M., Yeo T. C., Kong W. K. F., Poh K. K., Vilacosta I., Ferrera C., Olmos C., Abd El-Nasser M., Calvo Iglesias F., Blanco-Gonzalez E., Bravo Amaro M., Lopez-Rodriguez E., Lugo Adan J., Germinas A. N., Pazos-Lopez P., Pereira Loureiro M., Perez M. T., Raposeiras-Roubin S., Rasheed Yas S., Suarez-Varela M. -M., Vasallo Vidal F., Garcia-Dorado D., Fernandez-Hidalgo N., Gonzalez-Alujas T., Lozano J., Maisterra O., Pizzi N., Rios R., Bayes-Genis A., Pedro Botet L., Vallejo N., Llibre C., Mateu L., Nunez R., Quesada D., Berastegui E., Bosch Portell D., Aboal Vinas J., Albert Bertran X., Brugada Tarradellas R., Loma-Osorio Ricon P., Tiron De Llano C., Arnau M. A., Bel A., Blanes M., Osa A., Anguita M., Carrasco F., Castillo J. C., Zamorano J. L., Moya Mur J. L., Alvaro M., Fernandez-Golfin C., Monteagudo J. M., Navas Elorza E., Farinas Alvarez M. C., Aguero Balbin J., Zarauza J., Gutierrez-Diez J. F., Arminanzas C., Arnaiz De Las Revillas F., Arnaiz Garcia A., Cobo Belaustegui M., Fernandez Sampedro M., Gutierrez Cuadra M., Garcia Cuello L., Gonzalez Rico C., Rodriguez-Alvarez R., Goikoetxea J., Montejo M., Miro J. M., Almela M., Ambrosioni J., Moreno A., Quintana E., Sandoval E., Tellez A., Tolosana J. M., Vidal B., Falces C., Fuster D., Garcia-De-La-Maria C., Hernandez-Meneses M., Llopis J., Marco F., Ruiz-Zamora I., Bardaji Ruiz A., Sanz Girgas E., Garcia-Pardo G., Guillen Marzo M., Rodriguez Oviedo A., Villares Jimenez A., Abid L., Hammami R., Kammoun S., Mourali M. S., Ben Hlima M., Boudiche S., Ouali S., Zakhama L., Antit S., Slama I., Gulel O., Sahin M., Karacaglar E., Kucukoglu S., Cetinarslan O., Yasar U. S., Canpolat U., Mutlu B., Atas H., Dervishova R., Ileri C., Alhashmi J., Tahir J., Zarger P., Baslib F., Woldman S., Menezes L., Primus C., Uppal R., Bvekerwa I., Chandrasekaran B., Kopanska A., Chambers J., Hancock J., Klein J., Rajani R., Ursi M. P., Cannata S., Dworakowski R., Fife A., Breeze J., Browne-Morgan M., Gunning M., Streather S., Asch F. M., Zemedkun M., Alyavi B., Uzokov J., Cardiovascular Centre (CVC), Universidad de Cantabria, Habib, G, Lancellotti, P, Erba, P, Sadeghpour, A, Meshaal, M, Sambola, A, Furnaz, S, Citro, R, Ternacle, J, Donal, E, Cosyns, B, Popescu, B, Iung, B, Prendergast, B, Laroche, C, Tornos, P, Pazdernik, M, Maggioni, A, Gale, C, Ali Tatar-Chentir, N, Al-Mallah, M, Astrom Aneq, M, Athanassopoulos, G, Badano, L, Benyoussef, S, Calderon Aranda, E, Cardim, N, Chan, K, Cruz, I, Edvardsen, T, Goliasch, G, Hagendorff, A, Hristova, K, Kamp, O, Kang, D, Kong, W, Matskeplishvili, S, Mirocevic, M, Neskovic, A, Plonska-Gosciniak, E, Raissouni, M, Ronderos, R, Sade, L, Sengupta, S, Separovic-Hanzevacki, J, Takeuchi, M, Tucay, E, Tude Rodrigues, A, Varga, A, Vaskelyte, J, Yamagata, K, Yiangou, K, Zaky, H, Granada, I, Mahia, M, Ressi, S, Nacinovich, F, Iribarren, A, Fernandez Oses, P, Avegliano, G, Filipini, E, Obregon, R, Bangher, M, Dho, J, Cartasegna, L, Plastino, M, Novas, V, Shigel, C, Reyes, G, De Santos, M, Gastaldello, N, Granillo Fernandez, M, Potito, M, Streitenberger, G, Velazco, P, Casabe, J, Cortes, C, Guevara, E, Salmo, F, Seijo, M, Weidinger, F, Heger, M, Brooks, R, Stollberger, C, Ho, C, Perschy, L, Puskas, L, Binder, C, Rosenhek, R, Schneider, M, Winter, M, Hoffer, E, Melissopoulou, M, Lecoq, E, Legrand, D, Jacquet, S, Massoz, M, Pierard, L, Marchetta, S, Dulgheru, R, Emal, C, Oury, C, Droogmans, S, Kerkhove, D, Plein, D, Soens, L, Weytjens, C, Motoc, A, Roosens, B, Lemoine, I, Rodrigus, I, Paelinck, B, Amsel, B, Unger, P, Konopnicki, D, Beauloye, C, Pasquet, A, Vanoverschelde, J, Pierard, S, Vancraeynest, D, Sinnaeve, F, Andrade, J, Staszko, K, Dos Santos Monteiro, R, Miglioranza, M, Shuha, D, Alcantara, M, Cravo, V, Fazzio, L, Felix, A, Iso, M, Musa, C, Siciliano, A, Villaca Filho, F, Rodrigues, A, Vilela, F, Braga, J, Silva, R, Rodrigues, D, Silva, L, Morhy, S, Fischer, C, Vieira, M, Afonso, T, Abreu, J, Falcao, S, Moises, V, Gouvea, A, Mancuso, F, Souza, A, Silva, C, Joao, G, Abboud, C, Bellio De Mattos Barretto, R, Ramos, A, Arnoni, R, Assef, J, Della Togna, D, Bihan, D, Miglioli, L, Romero Oliveira, A, Tadeu Magro Kroll, R, Cortez, D, Gelape, C, Peirira Nunes, M, De Abreu Ferrari, T, Hay, K, Le, V, Page, M, Poulin, F, Sauve, C, Serri, K, Mercure, C, Beaudoin, J, Pibarot, P, Sebag, I, Rudski, L, Ricafort, G, Barsic, B, Krajinovic, V, Vargovic, M, Lovric, D, Reskovic-Luksic, V, Vincelj, J, Jaksic Jurinjak, S, Yiannikourides, V, Ioannides, M, Pofaides, C, Masoura, V, Pudich, J, Linhart, A, Siranec, M, Marek, J, Blechova, K, Kamenik, M, Pelouch, R, Coufal, Z, Mikulica, M, Griva, M, Jancova, E, Mikulcova, M, Taborsky, M, Precek, J, Jecmenova, M, Latal, J, Widimsky, J, Butta, T, Machacek, S, Vancata, R, Spinar, J, Holicka, M, Pow Chon Long, F, Anzules, N, Bajana Carpio, A, Largacha, G, Penaherrera, E, Moreira, D, Mahfouz, E, Elsafty, E, Soliman, A, Zayed, Y, Aboulenein, J, Abdel-Hay, M, Almaghraby, A, Abdelnaby, M, Ahmed, M, Hammad, B, Saleh, Y, Zahran, H, Elgebaly, O, Saad, A, Ali, M, Zeid, A, El Sharkawy, R, Al Kholy, A, Doss, R, Osama, D, Rizk, H, Elmogy, A, Mishriky, M, Assayag, P, El Hatimi, S, Hubert, S, Casalta, J, Gouriet, F, Arregle, F, Cammilleri, S, Tessonnier, L, Riberi, A, Botelho-Nevers, E, Gagneux-Brunon, A, Pierrard, R, Tulane, C, Campisi, S, Fuzellier, J, Detoc, M, Mehalla, T, Boutoille, D, Lecompte, A, Lefebvre, M, Pattier, S, Al Habash, O, Asseray-Madani, N, Biron, C, Brochard, J, Caillon, J, Cueff, C, Tourneau, T, Lecomte, R, Magali Michel, M, Orain, J, Delarue, S, Bras, M, Faucher, J, Aboyans, V, Beeharry, A, Durox, H, Lacoste, M, Magne, J, Mohty, D, David, A, Pradel, V, Sierra, V, Neykova, A, Bettayeb, B, Elkentaoui, S, Tzvetkov, B, Landry, G, Strady, C, Ainine, K, Baumard, S, Brasselet, C, Tassigny, C, Valente-Pires, V, Lefranc, M, Hoen, B, Lefevre, B, Curlier, E, Callier, C, Fourcade, N, Jobic, Y, Ansard, S, Berre, R, Ven, F, Pouliquen, M, Prat, G, Roux, P, Bouchart, F, Savoure, A, Alarcon, C, Chapuzet, C, Gueit, I, Tribouilloy, C, Bohbot, Y, Peugnet, F, Gun, M, Duval, X, Lescure, X, Ilic-Habensus, E, Sadoul, N, Selton-Suty, C, Alla, F, Goehringer, F, Huttin, O, Chevalier, E, Garcia, R, Marcis, V, Tattevin, P, Flecher, E, Revest, M, Chirouze, C, Bouiller, K, Hustache-Mathieu, L, Klopfenstein, T, Moreau, J, Fournier, D, Brunel, A, Lim, P, Oliver, L, Moussafeur, A, Chavanet, P, Piroth, L, Salmon-Rousseau, A, Buisson, M, Mahy, S, Martins, C, Gohier, S, Axler, O, Baumann, F, Lebras, S, Piper, C, Guckel, D, Borgermann, J, Horstkotte, D, Winkelmann, E, Brockmeier, B, Grey, D, Nickenig, G, Schueler, R, Ozturk, C, Stohr, E, Hamm, C, Walther, T, Brandt, R, Fruhauf, A, Hartung, C, Hellner, C, Wild, C, Becker, M, Hamada, S, Kaestner, W, Stangl, K, Knebel, F, Baldenhofer, G, Brecht, A, Dreger, H, Isner, C, Pfafflin, F, Stegemann, M, Zahn, R, Fraiture, B, Kilkowski, C, Karcher, A, Klinger, S, Tolksdorf, H, Tousoulis, D, Aggeli, C, Sideris, S, Venieri, E, Sarri, G, Tsiapras, D, Armenis, I, Koutsiari, A, Floros, G, Grassos, C, Dragasis, S, Rallidis, L, Varlamos, C, Michalis, L, Naka, K, Bechlioulis, A, Kotsia, A, Lakkas, L, Pappas, K, Papadopoulos, C, Kiokas, S, Lioni, A, Misailidou, S, Barbetseas, J, Bonou, M, Kapelios, C, Tomprou, I, Zerva, K, Manolis, A, Hamodraka, E, Athanasiou, D, Haralambidis, G, Samaras, H, Poulimenos, L, Nagy, A, Bartykowszki, A, Gara, E, Mungulmare, K, Kasliwal, R, Bansal, M, Ranjan, S, Bhan, A, Kyavar, M, Maleki, M, Noohi Bezanjani, F, Alizadehasl, A, Boudagh, S, Ghavidel, A, Moradnejad, P, Pasha, H, Ghadrdoost, B, Gilon, D, Strahilevitz, J, Wanounou, M, Israel, S, D'Agostino, C, Colonna, P, Michele, L, Fumarola, F, Stante, M, Marchionni, N, Scheggi, V, Alterini, B, Del Pace, S, Stefano, P, Sparano, C, Ruozi, N, Tenaglia, R, Muraru, D, Limbruno, U, Cresti, A, Baratta, P, Solari, M, Giannattasio, C, Moreo, A, Chiara, B, Lopez Montero, B, Musca, F, Orcese, C, Panzeri, F, Spano, F, Russo, C, Alfieri, O, Bonis, M, Chiappetta, S, Del Forno, B, Ripa, M, Scarpellini, P, Tassan Din, C, Castiglioni, B, Pasciuta, R, Carletti, S, Ferrara, D, Guffanti, M, Iaci, G, Lapenna, E, Nisi, T, Oltolini, C, Busnardo, E, Pajoro, U, Agricola, E, Meneghin, R, Schiavi, D, Piscione, F, Benvenga, R, Greco, L, Soriente, L, Radano, I, Prota, C, Bellino, M, Vece, D, Santini, F, Salsano, A, Olivieri, G, Turrini, F, Messora, R, Tondi, S, Olaru, A, Agnoletto, V, Grassi, L, Leonardi, C, Sansoni, S, Del Ponte, S, Actis Dato, G, Martino, A, Ohte, N, Kikuchi, S, Wakami, K, Aonuma, K, Seo, Y, Ishizu, T, MacHino-Ohtsuka, T, Yamamoto, M, Iida, N, Nakajima, H, Nakagawa, Y, Izumi, C, Amano, M, Miyake, M, Takahashi, K, Shiojima, I, Miyasaka, Y, Maeba, H, Suwa, Y, Taniguchi, N, Tsujimoto, S, Kitai, T, Ota, M, Yuda, S, Sasaki, S, Hagiwara, N, Yamazaki, K, Ashihara, K, Arai, K, Saitou, C, Saitou, S, Suzuki, G, Shibata, Y, Watanabe, N, Nishino, S, Ashikaga, K, Kuriyama, N, Mahara, K, Okubo, T, Fujimaki, H, Shitan, H, Yamamoto, H, Abe, K, Terada, M, Takanashi, S, Sata, M, Yamada, H, Kusunose, K, Saijo, Y, Seno, H, Yuichiro, O, Onishi, T, Sera, F, Nakatani, S, Mizuno, H, Sengoku, K, Park, S, Eun Kyoung, K, Ga Yeon, L, Hwang, J, Jin-Oh, C, Sang-Chol, L, Sung-A, C, Jang, S, Heo, R, Lee, S, Song, J, Jung, E, Plisiene, J, Dambrauskaite, A, Gruodyte, G, Jonkaitiene, R, Mizariene, V, Atkocaityte, J, Zvirblyte, R, Sow, R, Codreanu, A, Staub, T, Michaux, C, De La Vega, E, Jacobs-Orazi, L, Mallia Azzopardi, C, Xuereb, R, Piscopo, T, Farrugia, J, Fenech, M, Pllaha, E, Vella, C, Borg, D, Casha, R, Grib, L, Raevschi, E, Grejdieru, A, Kravcenco, D, Prisacari, E, Samohvalov, E, Samohvalov, S, Sceglova, N, Panfile, E, Cardaniuc, L, Corcea, V, Feodorovici, A, Gaina, V, Girbu, L, Jimbei, P, Balan, G, Cardaniuc, I, Benesco, I, Marian, V, Sumarga, N, Bozovic, B, Bulatovic, N, Lakovic, P, Music, L, Budde, R, Wahadat, A, Gamela, T, Meijers, T, Van Melle, J, Deursen, V, Crijns, H, Bekkers, S, Cheriex, E, Gilbers, M, Kietselaer, B, Knackstedt, C, Lorusso, R, Schalla, S, Streukens, S, Chamuleau, S, Cramer, M, Teske, A, Van Der Spoel, T, Wind, A, Lokhorst, J, Liesbek, O, Van Heusden, H, Tanis, W, Van Der Bilt, I, Vriend, J, Lange-Van Bruggen, H, Karijodikoro, E, Riezebos, R, Van Dongen, E, Schoep, J, Stolk, V, Offstad, J, Beitnes, J, Helle-Valle, T, Skulstad, H, Skardal, R, Qamar, N, Ahmed, B, Butt, M, Khanzada, M, Saghir, T, Wahid, A, Hryniewiecki, T, Szymanski, P, Marzec, K, Misztal-Ogonowska, M, Kosmala, W, Przewlocka-Kosmala, M, Rojek, A, Woznicka, K, Zachwyc, J, Lisowska, A, Kaminska, M, Kasprzak, J, Kowalczyk, E, Strzecka, D, Wejner-Mik, P, Trabulo, M, Freitas, P, Ranchordas, S, Rodrigues, G, Pinto, P, Queiros, C, Azevedo, J, Marques, L, Seabra, D, Branco, L, Cruz, M, Galrinho, A, Moreira, R, Rio, P, Timoteo, A, Selas, M, Carmelo, V, Duque Neves, B, Pereira, H, Guerra, A, Marques, A, Pintassilgo, I, Tomescu, M, Trofenciuc, N, Andor, M, Bordejevic, A, Branea, H, Caruntu, F, Velcean, L, Mavrea, A, Onel, M, Parvanescu, T, Pop, D, Pop-Moldovan, A, Puticiu, M, Cirin, L, Citu, I, Cotoraci, C, Darabantiu, D, Farcas, R, Marincu, I, Ionac, A, Cozma, D, Mornos, C, Goanta, F, Popescu, I, Beyer, R, Mada, R, Rancea, R, Tomoaia, R, Rosianu, H, Stanescu, C, Kobalava, Z, Karaulova, J, Kotova, E, Milto, A, Pisaryuk, A, Povalyaev, N, Sorokina, M, Alrahimi, J, Elshiekh, A, Jamiel, A, Ahmed, A, Attia, N, Putnikovic, B, Dimic, A, Ivanovic, B, Matic, S, Trifunovic, D, Petrovic, J, Kosevic, D, Stojanovic, I, Petrovic, I, Dabic, P, Milojevic, P, Srdanovic, I, Susak, S, Velicki, L, Vulin, A, Kovacevic, M, Redzek, A, Stefanovic, M, Yeo, T, Poh, K, Vilacosta, I, Ferrera, C, Olmos, C, Abd El-Nasser, M, Calvo Iglesias, F, Blanco-Gonzalez, E, Bravo Amaro, M, Lopez-Rodriguez, E, Lugo Adan, J, Germinas, A, Pazos-Lopez, P, Pereira Loureiro, M, Perez, M, Raposeiras-Roubin, S, Rasheed Yas, S, Suarez-Varela, M, Vasallo Vidal, F, Garcia-Dorado, D, Fernandez-Hidalgo, N, Gonzalez-Alujas, T, Lozano, J, Maisterra, O, Pizzi, N, Rios, R, Bayes-Genis, A, Pedro Botet, L, Vallejo, N, Llibre, C, Mateu, L, Nunez, R, Quesada, D, Berastegui, E, Bosch Portell, D, Aboal Vinas, J, Albert Bertran, X, Brugada Tarradellas, R, Loma-Osorio Ricon, P, Tiron De Llano, C, Arnau, M, Bel, A, Blanes, M, Osa, A, Anguita, M, Carrasco, F, Castillo, J, Zamorano, J, Moya Mur, J, Alvaro, M, Fernandez-Golfin, C, Monteagudo, J, Navas Elorza, E, Farinas Alvarez, M, Aguero Balbin, J, Zarauza, J, Gutierrez-Diez, J, Arminanzas, C, Arnaiz De Las Revillas, F, Arnaiz Garcia, A, Cobo Belaustegui, M, Fernandez Sampedro, M, Gutierrez Cuadra, M, Garcia Cuello, L, Gonzalez Rico, C, Rodriguez-Alvarez, R, Goikoetxea, J, Montejo, M, Miro, J, Almela, M, Ambrosioni, J, Moreno, A, Quintana, E, Sandoval, E, Tellez, A, Tolosana, J, Vidal, B, Falces, C, Fuster, D, Garcia-De-La-Maria, C, Hernandez-Meneses, M, Llopis, J, Marco, F, Ruiz-Zamora, I, Bardaji Ruiz, A, Sanz Girgas, E, Garcia-Pardo, G, Guillen Marzo, M, Rodriguez Oviedo, A, Villares Jimenez, A, Abid, L, Hammami, R, Kammoun, S, Mourali, M, Ben Hlima, M, Boudiche, S, Ouali, S, Zakhama, L, Antit, S, Slama, I, Gulel, O, Sahin, M, Karacaglar, E, Kucukoglu, S, Cetinarslan, O, Yasar, U, Canpolat, U, Mutlu, B, Atas, H, Dervishova, R, Ileri, C, Alhashmi, J, Tahir, J, Zarger, P, Baslib, F, Woldman, S, Menezes, L, Primus, C, Uppal, R, Bvekerwa, I, Chandrasekaran, B, Kopanska, A, Chambers, J, Hancock, J, Klein, J, Rajani, R, Ursi, M, Cannata, S, Dworakowski, R, Fife, A, Breeze, J, Browne-Morgan, M, Gunning, M, Streather, S, Asch, F, Zemedkun, M, Alyavi, B, Uzokov, J, UCL - SSS/IREC/CARD - Pôle de recherche cardiovasculaire, UCL - (SLuc) Service de pathologie cardiovasculaire, UCL - (SLuc) Service de pathologies cardiovasculaires intensives, UCL - (SLuc) Service de soins intensifs, Service de cardiologie, Université de la Méditerranée - Aix-Marseille 2-Assistance Publique - Hôpitaux de Marseille (APHM)- Hôpital de la Timone [CHU - APHM] (TIMONE), Service de cardiologie [Liège], CHU de Liège-Domaine Universitaire du Sart Tilman, University of Pisa - Università di Pisa, Institut Mondor de Recherche Biomédicale (IMRB), Institut National de la Santé et de la Recherche Médicale (INSERM)-IFR10-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12), Service de cardiologie et maladies vasculaires, Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Hôpital Pontchaillou-CHU Pontchaillou [Rennes], CIC - CHU Bichat, Institut National de la Santé et de la Recherche Médicale (INSERM), Oxford University Hospitals NHS Trust, University of Oxford [Oxford], Instituto Nacional de Tecnología Agropecuaria, Pergamino, Argentina, Laboratory of In Vivo Cellular and Molecular Imaging, Vrije Universiteit Brussel (VUB), Division of Engineering and Applied Science, California Institute of Technology, California Institute of Technology (CALTECH), Departamento de Biologia de la Reproduccion, Universidad Autónoma Metropolitana Iztapalapa (UAMI), Universidade Federal de Itajubá, Departamento de Física [Coimbra] (DFC), Universidade de Coimbra [Coimbra], Section of Internal Medicine and Endocrine and Metabolic Sciences, Università degli Studi di Perugia (UNIPG), Hôpital des Enfants, CHU Toulouse [Toulouse], Quebec Heart Institute/Laval Hospital, Université Laval [Québec] (ULaval)-Quebec Heart Institute, Institut Lavoisier de Versailles (ILV), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Centre National de la Recherche Scientifique (CNRS), Egyptian Geological Survey and Mining Authority, Institut Hospitalier Universitaire Méditerranée Infection (IHU AMU), Centre Hospitalier Universitaire de Saint-Etienne (CHU de Saint-Etienne), Service des maladies infectieuses et tropicales [CHU Nantes], Centre hospitalier universitaire de Nantes (CHU Nantes), Thérapeutiques cliniques et expérimentales des infections (EA 3826) (EA 3826), Université de Nantes - UFR de Médecine et des Techniques Médicales (UFR MEDECINE), Université de Nantes (UN)-Université de Nantes (UN), Service des Maladies infectieuses et tropicales [CHU Limoges], CHU Limoges, Neuroépidémiologie Tropicale (NET), Institut Génomique, Environnement, Immunité, Santé, Thérapeutique (GEIST), Université de Limoges (UNILIM)-Université de Limoges (UNILIM)-CHU Limoges-Institut d'Epidémiologie Neurologique et de Neurologie Tropicale-Institut National de la Santé et de la Recherche Médicale (INSERM), Hôpital Sainte-Marguerite [CHU - APHM] (Hôpitaux Sud ), Centre Hospitalier Universitaire de Reims (CHU Reims), Laboratoire Chrono-environnement - CNRS - UFC (UMR 6249) (LCE), Centre National de la Recherche Scientifique (CNRS)-Université de Franche-Comté (UFC), Université Bourgogne Franche-Comté [COMUE] (UBFC)-Université Bourgogne Franche-Comté [COMUE] (UBFC), Anesthésie et réanimation en chirurgie cardiaque [CHU Rouen], CHU Rouen, Normandie Université (NU)-Normandie Université (NU), Normandie Université (NU), Service des maladies infectieuses et tropicales [Rouen], Normandie Université (NU)-Normandie Université (NU)-Université de Rouen Normandie (UNIROUEN), Mécanismes physiologiques et conséquences des calcifications cardiovasculaires: rôle des remodelages cardiovasculaires et osseux, Université de Picardie Jules Verne (UPJV)-Institut National de la Santé et de la Recherche Médicale (INSERM), Department of Cardiology [Ospedali del Tigullio], Modèles et méthodes de l'évaluation thérapeutique des maladies chroniques (U738 / UMR_S738), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Diderot - Paris 7 (UPD7), Institut Lorrain du Coeur et des Vaisseaux Louis Mathieu [Nancy], Maladies chroniques, santé perçue, et processus d'adaptation (APEMAC), Université de Lorraine (UL), Service des Maladies Infectieuses et Tropicales [CHRU Nancy], Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy), Service de Cardiologie [CHRU Nancy], Service des maladies infectieuses et réanimation médicale, Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Hôpital Pontchaillou, Service de chirurgie thoracique cardiaque et vasculaire [Rennes], service de maladies infectieuses CHU J Minjoz Besancon, Hôpital Jean Minjoz, Centre Hospitalier Régional Universitaire [Besançon] (CHRU Besançon), Département d'infectiologie (CHU de Dijon), Centre Hospitalier Universitaire de Dijon - Hôpital François Mitterrand (CHU Dijon), Virologie et pathogenèse virale (VPV), Centre National de la Recherche Scientifique (CNRS)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon, Institució Catalana de Recerca i Estudis Avançats (ICREA), Shahed University [Téhéran], The University of Tokyo, University of North Carolina [Chapel Hill] (UNC), University of North Carolina System (UNC), Instituto de Investigaciones Marinas (CSIC), Paris-Centre de Recherche Cardiovasculaire (PARCC - UMR-S U970), Université Paris Descartes - Paris 5 (UPD5)-Hôpital Européen Georges Pompidou [APHP] (HEGP), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO)-Institut National de la Santé et de la Recherche Médicale (INSERM), Service de Chirurgie Cardiovasculaire, University Hospital of Cruces, Geneva University Hospital (HUG), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Universitat de Barcelona (UB), Preventive Medicine Unit, University Hospital Joan XXIII, IISPV, Rovira and Virgili University, Habib, G., Lancellotti, P., Erba, P. -A., Sadeghpour, A., Meshaal, M., Sambola, A., Furnaz, S., Citro, R., Ternacle, J., Donal, E., Cosyns, B., Popescu, B., Iung, B., Prendergast, B., Laroche, C., Tornos, P., Pazdernik, M., Maggioni, A., Gale, C. P., Ali Tatar-Chentir, N. N., Al-Mallah, M., Astrom Aneq, M., Athanassopoulos, G., Badano, L. P., Benyoussef, S., Calderon Aranda, E., Cardim, N. M., Chan, K. -L., Cruz, I., Edvardsen, T., Goliasch, G., Hagendorff, A., Hristova, K., Kamp, O., Kang, D. -H., Kong, W., Matskeplishvili, S., Mirocevic, M., Neskovic, A. N., Plonska-Gosciniak, E., Popescu, B. A., Raissouni, M., Ronderos, R., Sade, L. E., Sengupta, S., Separovic-Hanzevacki, J., Takeuchi, M., Tucay, E., Tude Rodrigues, A. C., Varga, A., Vaskelyte, J., Yamagata, K., Yiangou, K., Zaky, H., Granada, I., Mahia, M., Ressi, S., Nacinovich, F., Iribarren, A., Fernandez Oses, P., Avegliano, G., Filipini, E., Obregon, R., Bangher, M., Dho, J., Cartasegna, L., Plastino, M. L., Novas, V., Shigel, C., Reyes, G., De Santos, M., Gastaldello, N., Granillo Fernandez, M., Potito, M., Streitenberger, G., Velazco, P., Casabe, J. H., Cortes, C., Guevara, E., Salmo, F., Seijo, M., Weidinger, F., Heger, M., Brooks, R., Stollberger, C., Ho, C. -Y., Perschy, L., Puskas, L., Binder, C., Rosenhek, R., Schneider, M., Winter, M. -P., Hoffer, E., Melissopoulou, M., Lecoq, E., Legrand, D., Jacquet, S., Massoz, M., Pierard, L., Marchetta, S., Dulgheru, R., Emal, C. D., Oury, C., Droogmans, S., Kerkhove, D., Plein, D., Soens, L., Weytjens, C., Motoc, A., Roosens, B., Lemoine, I., Rodrigus, I., Paelinck, B., Amsel, B., Unger, P., Konopnicki, D., Beauloye, C., Pasquet, A., Vanoverschelde, J. L., Pierard, S., Vancraeynest, D., Sinnaeve, F., Andrade, J. L., Staszko, K., Dos Santos Monteiro, R., Miglioranza, M. H., Shuha, D. L., Alcantara, M., Cravo, V., Fazzio, L., Felix, A., Iso, M., Musa, C., Siciliano, A. P., Villaca Filho, F., Rodrigues, A., Vilela, F., Braga, J., Silva, R., Rodrigues, D., Silva, L., Morhy, S., Fischer, C., Vieira, M., Afonso, T., Abreu, J., Falcao, S. N., Moises, V. A., Gouvea, A., Mancuso, F. J., Souza, A. C., Silva, C. Y., Joao, G., Abboud, C. S., Bellio De Mattos Barretto, R., Ramos, A., Arnoni, R., Assef, J. E., Della Togna, D. J., Bihan, D. L., Miglioli, L., Romero Oliveira, A. P., Tadeu Magro Kroll, R., Cortez, D., Gelape, C. L., Peirira Nunes, M. D. C., De Abreu Ferrari, T. C., Hay, K., Le, V., Page, M., Poulin, F., Sauve, C., Serri, K., Mercure, C., Beaudoin, J., Pibarot, P., Sebag, I. A., Rudski, L. G., Ricafort, G., Barsic, B., Krajinovic, V., Vargovic, M., Lovric, D., Reskovic-Luksic, V., Vincelj, J., Jaksic Jurinjak, S., Yiannikourides, V., Ioannides, M., Pofaides, C., Masoura, V., Pudich, J., Linhart, A., Siranec, M., Marek, J., Blechova, K., Kamenik, M., Pelouch, R., Coufal, Z., Mikulica, M., Griva, M., Jancova, E., Mikulcova, M., Taborsky, M., Precek, J., Jecmenova, M., Latal, J., Widimsky, J., Butta, T., Machacek, S., Vancata, R., Spinar, J., Holicka, M., Pow Chon Long, F., Anzules, N., Bajana Carpio, A., Largacha, G., Penaherrera, E., Moreira, D., Mahfouz, E., Elsafty, E., Soliman, A., Zayed, Y., Aboulenein, J., Abdel-Hay, M., Almaghraby, A., Abdelnaby, M., Ahmed, M., Hammad, B., Saleh, Y., Zahran, H., Elgebaly, O., Saad, A., Ali, M., Zeid, A., El Sharkawy, R., Al Kholy, A., Doss, R., Osama, D., Rizk, H., Elmogy, A., Mishriky, M., Assayag, P., El Hatimi, S., Hubert, S., Casalta, J. -P., Gouriet, F., Arregle, F., Cammilleri, S., Tessonnier, L., Riberi, A., Botelho-Nevers, E., Gagneux-Brunon, A., Pierrard, R., Tulane, C., Campisi, S., Fuzellier, J. -F., Detoc, M., Mehalla, T., Boutoille, D., Lecompte, A. S., Lefebvre, M., Pattier, S., Al Habash, O., Asseray-Madani, N., Biron, C., Brochard, J., Caillon, J., Cueff, C., Tourneau, T. L., Lecomte, R., Magali Michel, M. M., Orain, J., Delarue, S., Bras, M. L., Faucher, J. -F., Aboyans, V., Beeharry, A., Durox, H., Lacoste, M., Magne, J., Mohty, D., David, A., Pradel, V., Sierra, V., Neykova, A., Bettayeb, B., Elkentaoui, S., Tzvetkov, B., Landry, G., Strady, C., Ainine, K., Baumard, S., Brasselet, C., Tassigny, C., Valente-Pires, V., Lefranc, M., Hoen, B., Lefevre, B., Curlier, E., Callier, C., Fourcade, N., Jobic, Y., Ansard, S., Berre, R. L., Ven, F. L., Pouliquen, M. -C., Prat, G., Roux, P. L., Bouchart, F., Savoure, A., Alarcon, C., Chapuzet, C., Gueit, I., Tribouilloy, C., Bohbot, Y., Peugnet, F., Gun, M., Duval, X., Lescure, X., Ilic-Habensus, E., Sadoul, N., Selton-Suty, C., Alla, F., Goehringer, F., Huttin, O., Chevalier, E., Garcia, R., Marcis, V. L., Tattevin, P., Flecher, E., Revest, M., Chirouze, C., Bouiller, K., Hustache-Mathieu, L., Klopfenstein, T., Moreau, J., Fournier, D., Brunel, A. -S., Lim, P., Oliver, L., Moussafeur, A., Chavanet, P., Piroth, L., Salmon-Rousseau, A., Buisson, M., Mahy, S., Martins, C., Gohier, S., Axler, O., Baumann, F., Lebras, S., Piper, C., Guckel, D., Borgermann, J., Horstkotte, D., Winkelmann, E., Brockmeier, B., Grey, D., Nickenig, G., Schueler, R., Ozturk, C., Stohr, E., Hamm, C., Walther, T., Brandt, R., Fruhauf, A. -C., Hartung, C. T., Hellner, C., Wild, C., Becker, M., Hamada, S., Kaestner, W., Stangl, K., Knebel, F., Baldenhofer, G., Brecht, A., Dreger, H., Isner, C., Pfafflin, F., Stegemann, M., Zahn, R., Fraiture, B., Kilkowski, C., Karcher, A. -K., Klinger, S., Tolksdorf, H., Tousoulis, D., Aggeli, C., Sideris, S., Venieri, E., Sarri, G., Tsiapras, D., Armenis, I., Koutsiari, A., Floros, G., Grassos, C., Dragasis, S., Rallidis, L., Varlamos, C., Michalis, L., Naka, K., Bechlioulis, A., Kotsia, A., Lakkas, L., Pappas, K., Papadopoulos, C., Kiokas, S., Lioni, A., Misailidou, S., Barbetseas, J., Bonou, M., Kapelios, C., Tomprou, I., Zerva, K., Manolis, A., Hamodraka, E., Athanasiou, D., Haralambidis, G., Samaras, H., Poulimenos, L., Nagy, A., Bartykowszki, A., Gara, E., Mungulmare, K., Kasliwal, R., Bansal, M., Ranjan, S., Bhan, A., Kyavar, M., Maleki, M., Noohi Bezanjani, F., Alizadehasl, A., Boudagh, S., Ghavidel, A., Moradnejad, P., Pasha, H. R., Ghadrdoost, B., Gilon, D., Strahilevitz, J., Wanounou, M., Israel, S., D'Agostino, C., Colonna, P., Michele, L. D., Fumarola, F., Stante, M., Marchionni, N., Scheggi, V., Alterini, B., Del Pace, S., Stefano, P., Sparano, C., Ruozi, N., Tenaglia, R., Muraru, D., Limbruno, U., Cresti, A., Baratta, P., Solari, M., Giannattasio, C., Moreo, A., Chiara, B. D., Lopez Montero, B., Musca, F., Orcese, C. A., Panzeri, F., Spano, F., Russo, C. F., Alfieri, O., De Bonis, M., Chiappetta, S., Del Forno, B., Ripa, M., Scarpellini, P., Tassan Din, C., Castiglioni, B., Pasciuta, R., Carletti, S., Ferrara, D., Guffanti, M., Iaci, G., Lapenna, E., Nisi, T., Oltolini, C., Busnardo, E., Pajoro, U., Agricola, E., Meneghin, R., Schiavi, D., Piscione, F., Benvenga, R. M., Greco, L., Soriente, L., Radano, I., Prota, C., Bellino, M., Vece, D. D., Santini, F., Salsano, A., Olivieri, G. M., Turrini, F., Messora, R., Tondi, S., Olaru, A., Agnoletto, V., Grassi, L., Leonardi, C., Sansoni, S., Del Ponte, S., Actis Dato, G. M., Martino, A. D., Ohte, N., Kikuchi, S., Wakami, K., Aonuma, K., Seo, Y., Ishizu, T., MacHino-Ohtsuka, T., Yamamoto, M., Iida, N., Nakajima, H., Nakagawa, Y., Izumi, C., Amano, M., Miyake, M., Takahashi, K., Shiojima, I., Miyasaka, Y., Maeba, H., Suwa, Y., Taniguchi, N., Tsujimoto, S., Kitai, T., Ota, M., Yuda, S., Sasaki, S., Hagiwara, N., Yamazaki, K., Ashihara, K., Arai, K., Saitou, C., Saitou, S., Suzuki, G., Shibata, Y., Watanabe, N., Nishino, S., Ashikaga, K., Kuriyama, N., Mahara, K., Okubo, T., Fujimaki, H., Shitan, H., Yamamoto, H., Abe, K., Terada, M., Takanashi, S., Sata, M., Yamada, H., Kusunose, K., Saijo, Y., Seno, H., Yuichiro, O., Onishi, T., Sera, F., Nakatani, S., Mizuno, H., Sengoku, K., Park, S. W., Eun Kyoung, K., Ga Yeon, L., Hwang, J. -W., Jin-Oh, C., Park, S. -J., Sang-Chol, L., Sung-A, C., Jang, S. Y., Heo, R., Lee, S., Song, J. -M., Jung, E., Plisiene, J., Dambrauskaite, A., Gruodyte, G., Jonkaitiene, R., Mizariene, V., Atkocaityte, J., Zvirblyte, R., Sow, R., Codreanu, A., Staub, T., Michaux, C., De La Vega, E. C. L., Jacobs-Orazi, L., Mallia Azzopardi, C., Xuereb, R. G., Piscopo, T., Farrugia, J., Fenech, M., Pllaha, E., Vella, C., Borg, D., Casha, R., Grib, L., Raevschi, E., Grejdieru, A., Kravcenco, D., Prisacari, E., Samohvalov, E., Samohvalov, S., Sceglova, N., Panfile, E., Cardaniuc, L., Corcea, V., Feodorovici, A., Gaina, V., Girbu, L., Jimbei, P., Balan, G., Cardaniuc, I., Benesco, I., Marian, V., Sumarga, N., Bozovic, B., Bulatovic, N., Lakovic, P., Music, L., Budde, R., Wahadat, A., Gamela, T., Meijers, T., Van Melle, J. P., Deursen, V. M., Crijns, H. J., Bekkers, S. C., Cheriex, E. C., Gilbers, M., Kietselaer, B. L., Knackstedt, C., Lorusso, R., Schalla, S., Streukens, S. A., Chamuleau, S., Cramer, M. -J., Teske, A., Van Der Spoel, T., Wind, A., Lokhorst, J., Liesbek, O., Van Heusden, H., Tanis, W., Van Der Bilt, I., Vriend, J., Lange-Van Bruggen, H. D., Karijodikoro, E., Riezebos, R., Van Dongen, E., Schoep, J., Stolk, V., Offstad, J. T., Beitnes, J. O., Helle-Valle, T., Skulstad, H., Skardal, R., Qamar, N., Ahmed, B., Butt, M. H., Khanzada, M. F., Saghir, T., Wahid, A., Hryniewiecki, T., Szymanski, P., Marzec, K., Misztal-Ogonowska, M., Kosmala, W., Przewlocka-Kosmala, M., Rojek, A., Woznicka, K., Zachwyc, J., Lisowska, A., Kaminska, M., Kasprzak, J. D., Kowalczyk, E., Strzecka, D. F., Wejner-Mik, P., Trabulo, M., Freitas, P., Ranchordas, S., Rodrigues, G., Pinto, P., Queiros, C., Azevedo, J., Marques, L., Seabra, D., Branco, L., Cruz, M., Galrinho, A., Moreira, R., Rio, P., Timoteo, A. T., Selas, M., Carmelo, V., Duque Neves, B., Pereira, H., Guerra, A., Marques, A., Pintassilgo, I., Tomescu, M. C., Trofenciuc, N. -M., Andor, M., Bordejevic, A., Branea, H. S., Caruntu, F., Velcean, L. A., Mavrea, A., Onel, M. F., Parvanescu, T., Pop, D., Pop-Moldovan, A. L., Puticiu, M. I., Cirin, L., Citu, I. M., Cotoraci, C. A., Darabantiu, D., Farcas, R., Marincu, I., Ionac, A., Cozma, D., Mornos, C., Goanta, F., Popescu, I., Beyer, R., Mada, R., Rancea, R., Tomoaia, R., Rosianu, H., Stanescu, C., Kobalava, Z., Karaulova, J., Kotova, E., Milto, A., Pisaryuk, A., Povalyaev, N., Sorokina, M., Alrahimi, J., Elshiekh, A., Jamiel, A., Ahmed, A., Attia, N., Putnikovic, B., Dimic, A., Ivanovic, B., Matic, S., Trifunovic, D., Petrovic, J., Kosevic, D., Stojanovic, I., Petrovic, I., Dabic, P., Milojevic, P., Srdanovic, I., Susak, S., Velicki, L., Vulin, A., Kovacevic, M., Redzek, A., Stefanovic, M., Yeo, T. C., Kong, W. K. F., Poh, K. K., Vilacosta, I., Ferrera, C., Olmos, C., Abd El-Nasser, M., Calvo Iglesias, F., Blanco-Gonzalez, E., Bravo Amaro, M., Lopez-Rodriguez, E., Lugo Adan, J., Germinas, A. N., Pazos-Lopez, P., Pereira Loureiro, M., Perez, M. T., Raposeiras-Roubin, S., Rasheed Yas, S., Suarez-Varela, M. -M., Vasallo Vidal, F., Garcia-Dorado, D., Fernandez-Hidalgo, N., Gonzalez-Alujas, T., Lozano, J., Maisterra, O., Pizzi, N., Rios, R., Bayes-Genis, A., Pedro Botet, L., Vallejo, N., Llibre, C., Mateu, L., Nunez, R., Quesada, D., Berastegui, E., Bosch Portell, D., Aboal Vinas, J., Albert Bertran, X., Brugada Tarradellas, R., Loma-Osorio Ricon, P., Tiron De Llano, C., Arnau, M. A., Bel, A., Blanes, M., Osa, A., Anguita, M., Carrasco, F., Castillo, J. C., Zamorano, J. L., Moya Mur, J. L., Alvaro, M., Fernandez-Golfin, C., Monteagudo, J. M., Navas Elorza, E., Farinas Alvarez, M. C., Aguero Balbin, J., Zarauza, J., Gutierrez-Diez, J. F., Arminanzas, C., Arnaiz De Las Revillas, F., Arnaiz Garcia, A., Cobo Belaustegui, M., Fernandez Sampedro, M., Gutierrez Cuadra, M., Garcia Cuello, L., Gonzalez Rico, C., Rodriguez-Alvarez, R., Goikoetxea, J., Montejo, M., Miro, J. M., Almela, M., Ambrosioni, J., Moreno, A., Quintana, E., Sandoval, E., Tellez, A., Tolosana, J. M., Vidal, B., Falces, C., Fuster, D., Garcia-De-La-Maria, C., Hernandez-Meneses, M., Llopis, J., Marco, F., Ruiz-Zamora, I., Bardaji Ruiz, A., Sanz Girgas, E., Garcia-Pardo, G., Guillen Marzo, M., Rodriguez Oviedo, A., Villares Jimenez, A., Abid, L., Hammami, R., Kammoun, S., Mourali, M. S., Ben Hlima, M., Boudiche, S., Ouali, S., Zakhama, L., Antit, S., Slama, I., Gulel, O., Sahin, M., Karacaglar, E., Kucukoglu, S., Cetinarslan, O., Yasar, U. S., Canpolat, U., Mutlu, B., Atas, H., Dervishova, R., Ileri, C., Alhashmi, J., Tahir, J., Zarger, P., Baslib, F., Woldman, S., Menezes, L., Primus, C., Uppal, R., Bvekerwa, I., Chandrasekaran, B., Kopanska, A., Chambers, J., Hancock, J., Klein, J., Rajani, R., Ursi, M. P., Cannata, S., Dworakowski, R., Fife, A., Breeze, J., Browne-Morgan, M., Gunning, M., Streather, S., Asch, F. M., Zemedkun, M., Alyavi, B., Uzokov, J., RS: Carim - H01 Clinical atrial fibrillation, MUMC+: MA Cardiologie (9), Cardiologie, RS: CARIM - R3.11 - Imaging, RS: CARIM - R2.01 - Clinical atrial fibrillation, MUMC+: MA Med Staf Artsass CTC (9), Promovendi CD, Fysiologie, RS: CARIM - R1.06 - Genetic Epidemiology and Genomics of cardiovascular diseases, MUMC+: MA Med Staf Spec Cardiologie (9), RS: Carim - V04 Surgical intervention, CTC, MUMC+: MA Med Staf Spec CTC (9), RS: CARIM - R2.12 - Surgical intervention, RS: Carim - H02 Cardiomyopathy, and RS: CARIM - R2.02 - Cardiomyopathy

Subjects
medicine.medical_specialty, Registry, MEDLINE, Infective endocarditi, infective endocarditis, registry, valve disease, Disease, Infective endocarditis, Valve disease, 030204 cardiovascular system & hematology, 03 medical and health sciences, 0302 clinical medicine, Epidemiology, medicine, Journal Article, MANAGEMENT, Endocarditis, Humans, 030212 general & internal medicine, Registries, Intensive care medicine, health care economics and organizations, Surrogate endpoint, business.industry, Health Policy, Patient data, MED/11 - MALATTIE DELL'APPARATO CARDIOVASCOLARE, medicine.disease, 3. Good health, Cardiac surgery, Europe, Practice Guidelines as Topic, business, Cardiology and Cardiovascular Medicine, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
Abstract

Aims The European Society of Cardiology (ESC) EURObservational Research Programme (EORP) European Endocarditis (EURO-ENDO) registry aims to study the care and outcomes of patients diagnosed with infective endocarditis (IE) and compare findings with recommendations from the 2015 ESC Clinical Practice Guidelines for the management of IE and data from the 2001 Euro Heart Survey. Methods and results Patients (n = 3116) aged over 18 years with a diagnosis of IE based on the ESC 2015 IE diagnostic criteria were prospectively identified between 1 January 2016 and 31 March 2018. Individual patient data were collected across 156 centres and 40 countries. The primary endpoint is all-cause mortality in hospital and at 1 year. Secondary endpoints are 1-year morbidity (all-cause hospitalization, any cardiac surgery, and IE relapse), the clinical, epidemiological, microbiological, and therapeutic characteristics of patients, the number and timing of non-invasive imaging techniques, and adherence to recommendations as stated in the 2015 ESC Clinical Practice Guidelines for the management of IE. Conclusion EURO-ENDO is an international registry of care and outcomes of patients hospitalized with IE which will provide insights into the contemporary profile and management of patients with this challenging disease.

Published
2019

16. Clinical presentation, aetiology and outcome of infective endocarditis. Results of the ESC-EORP EURO-ENDO (European infective endocarditis) registry: A prospective cohort study

Author

Habib, G, Erba, P, Iung, B, Donal, E, Cosyns, B, Laroche, C, Popescu, B, Prendergast, B, Tornos, P, Sadeghpour, A, Oliver, L, Vaskelyte, J, Sow, R, Axler, O, Maggioni, A, Lancellotti, P, Gale, C, Beleslin, B, Budaj, A, Chioncel, O, Dagres, N, Danchin, N, Emberson, J, Erlinge, D, Glikson, M, Gray, A, Kayikcioglu, M, Nagy, V, Nedoshivin, A, Petronio, A, Roos-Hesselink, J, Wallentin, L, Zeymer, U, Andarala, M, Berle, C, Brunel-Lebecq, A, Fiorucci, E, Missiamenou, V, Taylor, C, Ali Tatar-Chentir, N, Al-Mallah, M, Astrom Aneq, M, Athanassopoulos, G, Badano, L, Benyoussef, S, Calderon Aranda, E, Cardim, N, Chan, K, Cruz, I, Edvardsen, T, Goliasch, G, Hagendorff, A, Hristova, K, Kamp, O, Kang, D, Kong, W, Matskeplishvili, S, Meshaal, M, Mirocevic, M, Neskovic, A, Pazdernik, M, Plonska-Gosciniak, E, Raissouni, M, Ronderos, R, Sade, L, Sambola, A, Sengupta, S, Separovic-Hanzevacki, J, Takeuchi, M, Tucay, E, Tude Rodrigues, A, Varga, A, Yamagata, K, Yiangou, K, Zaky, H, Granada, I, Mahia, M, Ressi, S, Nacinovich, F, Iribarren, A, Fernandez Oses, P, Avegliano, G, Filipini, E, Obregon, R, Bangher, M, Dho, J, Cartasegna, L, Plastino, M, Novas, V, Shigel, C, Reyes, G, De Santos, M, Gastaldello, N, Granillo Fernandez, M, Potito, M, Streitenberger, G, Velazco, P, Casabe, J, Cortes, C, Guevara, E, Salmo, F, Seijo, M, Weidinger, F, Heger, M, Brooks, R, Stollberger, C, Ho, C, Perschy, L, Puskas, L, Binder, C, Rosenhek, R, Schneider, M, Winter, M, Hoffer, E, Melissopoulou, M, Lecoq, E, Legrand, D, Jacquet, S, Massoz, M, Pierard, L, Marchetta, S, Dulgheru, R, Emal, C, Oury, C, Droogmans, S, Kerkhove, D, Plein, D, Soens, L, Weytjens, C, Motoc, A, Roosens, B, Lemoine, I, Rodrigus, I, Paelinck, B, Amsel, B, Unger, P, Konopnicki, D, Beauloye, C, Pasquet, A, Vanoverschelde, J, Pierard, S, Vancraeynest, D, Sinnaeve, F, Andrade, J, Staszko, K, Dos Santos Monteiro, R, Miglioranza, M, Shuha, D, Alcantara, M, Cravo, V, Fazzio, L, Felix, A, Iso, M, Musa, C, Siciliano, A, Villaca Filho, F, Rodrigues, A, Vilela, F, Braga, J, Silva, R, Rodrigues, D, Silva, L, Morhy, S, Fischer, C, Vieira, M, Afonso, T, Abreu, J, Falcao, S, Moises, V, Gouvea, A, Mancuso, F, Souza, A, Silva, C, Joao, G, Abboud, C, Bellio de Mattos Barretto, R, Ramos, A, Arnoni, R, Assef, J, Della Togna, D, Le Bihan, D, Miglioli, L, Romero Oliveira, A, Tadeu Magro Kroll, R, Cortez, D, Gelape, C, Peirira Nunes, M, De Abreu Ferrari, T, Hay, K, Le, V, Page, M, Poulin, F, Sauve, C, Serri, K, Mercure, C, Beaudoin, J, Pibarot, P, Sebag, I, Rudski, L, Ricafort, G, Barsic, B, Krajinovic, V, Vargovic, M, Lovric, D, Reskovic-Luksic, V, Vincelj, J, Jaksic Jurinjak, S, Yiannikourides, V, Ioannides, M, Pofaides, C, Masoura, V, Pudich, J, Linhart, A, Siranec, M, Marek, J, Blechova, K, Kamenik, M, Pelouch, R, Coufal, Z, Mikulica, M, Griva, M, Jancova, E, Mikulcova, M, Taborsky, M, Precek, J, Jecmenova, M, Latal, J, Widimsky, J, Butta, T, Machacek, S, Vancata, R, Spinar, J, Holicka, M, Pow Chon Long, F, Anzules, N, Bajana Carpio, A, Largacha, G, Penaherrera, E, Moreira, D, Mahfouz, E, Elsafty, E, Soliman, A, Zayed, Y, Aboulenein, J, Abdel-Hay, M, Almaghraby, A, Abdelnaby, M, Ahmed, M, Hammad, B, Saleh, Y, Zahran, H, Elgebaly, O, Saad, A, Ali, M, Zeid, A, El Sharkawy, R, Al Kholy, A, Doss, R, Osama, D, Rizk, H, Elmogy, A, Mishriky, M, Assayag, P, El Hatimi, S, Hubert, S, Casalta, J, Gouriet, F, Arregle, F, Cammilleri, S, Tessonnier, L, Riberi, A, Botelho-Nevers, E, Gagneux-Brunon, A, Pierrard, R, Tulane, C, Campisi, S, Fuzellier, J, Detoc, M, Mehalla, T, Boutoille, D, Lecompte, A, Lefebvre, M, Pattier, S, Al Habash, O, Asseray-Madani, N, Biron, C, Brochard, J, Caillon, J, Cueff, C, Le Tourneau, T, Lecomte, R, Magali Michel, M, Orain, J, Delarue, S, Le Bras, M, Faucher, J, Aboyans, V, Beeharry, A, Durox, H, Lacoste, M, Magne, J, Mohty, D, David, A, Pradel, V, Sierra, V, Neykova, A, Bettayeb, B, Elkentaoui, S, Tzvetkov, B, Landry, G, Strady, C, Ainine, K, Baumard, S, Brasselet, C, Tassigny, C, Valente-Pires, V, Lefranc, M, Hoen, B, Lefevre, B, Curlier, E, Callier, C, Fourcade, N, Jobic, Y, Ansard, S, Le Berre, R, Le Ven, F, Pouliquen, M, Prat, G, Le Roux, P, Bouchart, F, Savoure, A, Alarcon, C, Chapuzet, C, Gueit, I, Tribouilloy, C, Bohbot, Y, Peugnet, F, Gun, M, Duval, X, Lescure, X, Ilic-Habensus, E, Sadoul, N, Selton-Suty, C, Alla, F, Goehringer, F, Huttin, O, Chevalier, E, Garcia, R, Le Marcis, V, Tattevin, P, Flecher, E, Revest, M, Chirouze, C, Bouiller, K, Hustache-Mathieu, L, Klopfenstein, T, Moreau, J, Fournier, D, Brunel, A, Lim, P, Ternacle, J, Moussafeur, A, Chavanet, P, Piroth, L, Salmon-Rousseau, A, Buisson, M, Mahy, S, Martins, C, Gohier, S, Baumann, F, Lebras, S, Piper, C, Guckel, D, Borgermann, J, Horstkotte, D, Winkelmann, E, Brockmeier, B, Grey, D, Nickenig, G, Schueler, R, Ozturk, C, Stohr, E, Hamm, C, Walther, T, Brandt, R, Fruhauf, A, Hartung, C, Hellner, C, Wild, C, Becker, M, Hamada, S, Kaestner, W, Stangl, K, Knebel, F, Baldenhofer, G, Brecht, A, Dreger, H, Isner, C, Pfafflin, F, Stegemann, M, Zahn, R, Fraiture, B, Kilkowski, C, Karcher, A, Klinger, S, Tolksdorf, H, Tousoulis, D, Aggeli, C, Sideris, S, Venieri, E, Sarri, G, Tsiapras, D, Armenis, I, Koutsiari, A, Floros, G, Grassos, C, Dragasis, S, Rallidis, L, Varlamos, C, Michalis, L, Naka, K, Bechlioulis, A, Kotsia, A, Lakkas, L, Pappas, K, Papadopoulos, C, Kiokas, S, Lioni, A, Misailidou, S, Barbetseas, J, Bonou, M, Kapelios, C, Tomprou, I, Zerva, K, Manolis, A, Hamodraka, E, Athanasiou, D, Haralambidis, G, Samaras, H, Poulimenos, L, Nagy, A, Bartykowszki, A, Gara, E, Mungulmare, K, Kasliwal, R, Bansal, M, Ranjan, S, Bhan, A, Kyavar, M, Maleki, M, Noohi Bezanjani, F, Alizadehasl, A, Boudagh, S, Ghavidel, A, Moradnejad, P, Pasha, H, Ghadrdoost, B, Gilon, D, Strahilevitz, J, Wanounou, M, Israel, S, D'Agostino, C, Colonna, P, De Michele, L, Fumarola, F, Stante, M, Marchionni, N, Scheggi, V, Alterini, B, Del Pace, S, Stefano, P, Sparano, C, Ruozi, N, Tenaglia, R, Muraru, D, Limbruno, U, Cresti, A, Baratta, P, Solari, M, Giannattasio, C, Moreo, A, De Chiara, B, Lopez Montero, B, Musca, F, Orcese, C, Panzeri, F, Spano, F, Russo, C, Alfieri, O, De Bonis, M, Chiappetta, S, Del Forno, B, Ripa, M, Scarpellini, P, Tassan Din, C, Castiglioni, B, Pasciuta, R, Carletti, S, Ferrara, D, Guffanti, M, Iaci, G, Lapenna, E, Nisi, T, Oltolini, C, Busnardo, E, Pajoro, U, Agricola, E, Meneghin, R, Schiavi, D, Piscione, F, Citro, R, Benvenga, R, Greco, L, Soriente, L, Radano, I, Prota, C, Bellino, M, Di Vece, D, Santini, F, Salsano, A, Olivieri, G, Turrini, F, Messora, R, Tondi, S, Olaru, A, Agnoletto, V, Grassi, L, Leonardi, C, Sansoni, S, Del Ponte, S, Actis Dato, G, De Martino, A, Ohte, N, Kikuchi, S, Wakami, K, Aonuma, K, Seo, Y, Ishizu, T, Machino-Ohtsuka, T, Yamamoto, M, Iida, N, Nakajima, H, Nakagawa, Y, Izumi, C, Amano, M, Miyake, M, Takahashi, K, Shiojima, I, Miyasaka, Y, Maeba, H, Suwa, Y, Taniguchi, N, Tsujimoto, S, Kitai, T, Ota, M, Yuda, S, Sasaki, S, Hagiwara, N, Yamazaki, K, Ashihara, K, Arai, K, Saitou, C, Saitou, S, Suzuki, G, Shibata, Y, Watanabe, N, Nishino, S, Ashikaga, K, Kuriyama, N, Mahara, K, Okubo, T, Fujimaki, H, Shitan, H, Yamamoto, H, Abe, K, Terada, M, Takanashi, S, Sata, M, Yamada, H, Kusunose, K, Saijo, Y, Seno, H, Yuichiro, O, Onishi, T, Sera, F, Nakatani, S, Mizuno, H, Sengoku, K, Park, S, Eun Kyoung, K, Ga Yeon, L, Hwang, J, Jin-Oh, C, Sang-Chol, L, Sung-A, C, Jang, S, Heo, R, Lee, S, Song, J, Jung, E, Plisiene, J, Dambrauskaite, A, Gruodyte, G, Jonkaitiene, R, Mizariene, V, Atkocaityte, J, Zvirblyte, R, Codreanu, A, Staub, T, Michaux, C, De la Vega, E, Jacobs-Orazi, L, Mallia Azzopardi, C, Xuereb, R, Piscopo, T, Farrugia, J, Fenech, M, Pllaha, E, Vella, C, Borg, D, Casha, R, Grib, L, Raevschi, E, Grejdieru, A, Kravcenco, D, Prisacari, E, Samohvalov, E, Samohvalov, S, Sceglova, N, Panfile, E, Cardaniuc, L, Corcea, V, Feodorovici, A, Gaina, V, Girbu, L, Jimbei, P, Balan, G, Cardaniuc, I, Benesco, I, Marian, V, Sumarga, N, Bozovic, B, Bulatovic, N, Lakovic, P, Music, L, Budde, R, Wahadat, A, Gamela, T, Meijers, T, Van Melle, J, Deursen, V, Crijns, H, Bekkers, S, Cheriex, E, Gilbers, M, Kietselaer, B, Knackstedt, C, Lorusso, R, Schalla, S, Streukens, S, Chamuleau, S, Cramer, M, Teske, A, Van der Spoel, T, Wind, A, Lokhorst, J, Liesbek, O, Van Heusden, H, Tanis, W, Van der Bilt, I, Vriend, J, De Lange-van Bruggen, H, Karijodikoro, E, Riezebos, R, van Dongen, E, Schoep, J, Stolk, V, Offstad, J, Beitnes, J, Helle-Valle, T, Skulstad, H, Skardal, R, Qamar, N, Furnaz, S, Ahmed, B, Butt, M, Khanzada, M, Saghir, T, Wahid, A, Hryniewiecki, T, Szymanski, P, Marzec, K, Misztal-Ogonowska, M, Kosmala, W, Przewlocka-Kosmala, M, Rojek, A, Woznicka, K, Zachwyc, J, Lisowska, A, Kaminska, M, Kasprzak, J, Kowalczyk, E, Strzecka, D, Wejner-Mik, P, Trabulo, M, Freitas, P, Ranchordas, S, Rodrigues, G, Pinto, P, Queiros, C, Azevedo, J, Marques, L, Seabra, D, Branco, L, Cruz, M, Galrinho, A, Moreira, R, Rio, P, Timoteo, A, Selas, M, Carmelo, V, Duque Neves, B, Pereira, H, Guerra, A, Marques, A, Pintassilgo, I, Tomescu, M, Trofenciuc, N, Andor, M, Bordejevic, A, Branea, H, Caruntu, F, Velcean, L, Mavrea, A, Onel, M, Parvanescu, T, Pop, D, Pop-Moldovan, A, Puticiu, M, Cirin, L, Citu, I, Cotoraci, C, Darabantiu, D, Farcas, R, Marincu, I, Ionac, A, Cozma, D, Mornos, C, Goanta, F, Popescu, I, Beyer, R, Mada, R, Rancea, R, Tomoaia, R, Rosianu, H, Stanescu, C, Kobalava, Z, Karaulova, J, Kotova, E, Milto, A, Pisaryuk, A, Povalyaev, N, Sorokina, M, Alrahimi, J, Elshiekh, A, Jamiel, A, Ahmed, A, Attia, N, Putnikovic, B, Dimic, A, Ivanovic, B, Matic, S, Trifunovic, D, Petrovic, J, Kosevic, D, Stojanovic, I, Petrovic, I, Dabic, P, Milojevic, P, Srdanovic, I, Susak, S, Velicki, L, Vulin, A, Kovacevic, M, Redzek, A, Stefanovic, M, Yeo, T, Poh, K, Vilacosta, I, Ferrera, C, Olmos, C, Abd El-Nasser, M, Calvo Iglesias, F, Blanco-Gonzalez, E, Bravo Amaro, M, Lopez-Rodriguez, E, Lugo Adan, J, Germinas, A, Pazos-Lopez, P, Pereira Loureiro, M, Perez, M, Raposeiras-Roubin, S, Rasheed Yas, S, Suarez-Varela, M, Vasallo Vidal, F, Garcia-Dorado, D, Fernandez-Hidalgo, N, Gonzalez-Alujas, T, Lozano, J, Maisterra, O, Pizzi, N, Rios, R, Bayes-Genis, A, Pedro Botet, L, Vallejo, N, Llibre, C, Mateu, L, Nunez, R, Quesada, D, Berastegui, E, Bosch Portell, D, Aboal Vinas, J, Albert Bertran, X, Brugada Tarradellas, R, Loma-Osorio Ricon, P, Tiron de Llano, C, Arnau, M, Bel, A, Blanes, M, Osa, A, Anguita, M, Carrasco, F, Castillo, J, Zamorano, J, Moya Mur, J, Alvaro, M, Fernandez-Golfin, C, Monteagudo, J, Navas Elorza, E, Farinas Alvarez, M, Aguero Balbin, J, Zarauza, J, Gutierrez-Diez, J, Arminanzas, C, Arnaiz de Las Revillas, F, Arnaiz Garcia, A, Cobo Belaustegui, M, Fernandez Sampedro, M, Gutierrez Cuadra, M, Garcia Cuello, L, Gonzalez Rico, C, Rodriguez-Alvarez, R, Goikoetxea, J, Montejo, M, Miro, J, Almela, M, Ambrosioni, J, Moreno, A, Quintana, E, Sandoval, E, Tellez, A, Tolosana, J, Vidal, B, Falces, C, Fuster, D, Garcia-de-la-Maria, C, Hernandez-Meneses, M, Llopis, J, Marco, F, Ruiz-Zamora, I, Bardaji Ruiz, A, Sanz Girgas, E, Garcia-Pardo, G, Guillen Marzo, M, Rodriguez Oviedo, A, Villares Jimenez, A, Abid, L, Hammami, R, Kammoun, S, Mourali, M, Ben Hlima, M, Boudiche, S, Ouali, S, Zakhama, L, Antit, S, Slama, I, Gulel, O, Sahin, M, Karacaglar, E, Kucukoglu, S, Cetinarslan, O, Yasar, U, Canpolat, U, Mutlu, B, Atas, H, Dervishova, R, Ileri, C, Alhashmi, J, Tahir, J, Zarger, P, Baslib, F, Woldman, S, Menezes, L, Primus, C, Uppal, R, Bvekerwa, I, Chandrasekaran, B, Kopanska, A, Chambers, J, Hancock, J, Klein, J, Rajani, R, Ursi, M, Cannata, S, Dworakowski, R, Fife, A, Breeze, J, Browne-Morgan, M, Gunning, M, Streather, S, Asch, F, Zemedkun, M, Alyavi, B, Uzokov, J, Habib G., Erba P. A., Iung B., Donal E., Cosyns B., Laroche C., Popescu B. A., Prendergast B., Tornos P., Sadeghpour A., Oliver L., Vaskelyte J. -J., Sow R., Axler O., Maggioni A. P., Lancellotti P., Gale C. P., Beleslin B., Budaj A., Chioncel O., Dagres N., Danchin N., Emberson J., Erlinge D., Glikson M., Gray A., Kayikcioglu M., Nagy V. K., Nedoshivin A., Petronio A. S., Roos-Hesselink J., Wallentin L., Zeymer U., Andarala M., Berle C., Brunel-Lebecq A., Fiorucci E., Missiamenou V., Taylor C., Ali Tatar-Chentir N. N., Al-Mallah M., Astrom Aneq M., Athanassopoulos G., Badano L. P., Benyoussef S., Calderon Aranda E., Cardim N. M., Chan K. L., Cruz I., Edvardsen T., Goliasch G., Hagendorff A., Hristova K., Kamp O., Kang D. H., Kong W., Matskeplishvili S., Meshaal M., Mirocevic M., Neskovic A. N., Pazdernik M., Plonska-Gosciniak E., Raissouni M., Ronderos R., Sade L. E., Sambola A., Sengupta S., Separovic-Hanzevacki J., Takeuchi M., Tucay E., Tude Rodrigues A. C., Varga A., Yamagata K., Yiangou K., Zaky H., Granada I., Mahia M., Ressi S., Nacinovich F., Iribarren A., Fernandez Oses P., Avegliano G., Filipini E., Obregon R., Bangher M., Dho J., Cartasegna L., Plastino M. L., Novas V., Shigel C., Reyes G., De Santos M., Gastaldello N., Granillo Fernandez M., Potito M., Streitenberger G., Velazco P., Casabe J. H., Cortes C., Guevara E., Salmo F., Seijo M., Weidinger F., Heger M., Brooks R., Stollberger C., Ho C. Y., Perschy L., Puskas L., Binder C., Rosenhek R., Schneider M., Winter M. P., Hoffer E., Melissopoulou M., Lecoq E., Legrand D., Jacquet S., Massoz M., Pierard L., Marchetta S., Dulgheru R., Emal C. D., Oury C., Droogmans S., Kerkhove D., Plein D., Soens L., Weytjens C., Motoc A., Roosens B., Lemoine I., Rodrigus I., Paelinck B., Amsel B., Unger P., Konopnicki D., Beauloye C., Pasquet A., Vanoverschelde J. L., Pierard S., Vancraeynest D., Sinnaeve F., Andrade J. L., Staszko K., Dos Santos Monteiro R., Miglioranza M. H., Shuha D. L., Alcantara M., Cravo V., Fazzio L., Felix A., Iso M., Musa C., Siciliano A. P., Villaca Filho F., Rodrigues A., Vilela F., Braga J., Silva R., Rodrigues D., Silva L., Morhy S., Fischer C., Vieira M., Afonso T., Abreu J., Falcao S. N., Moises V. A., Gouvea A., Mancuso F. J., Souza A. C., Silva C. Y., Joao G., Abboud C. S., Bellio de Mattos Barretto R., Ramos A., Arnoni R., Assef J. E., Della Togna D. J., Le Bihan D., Miglioli L., Romero Oliveira A. P., Tadeu Magro Kroll R., Cortez D., Gelape C. L., Peirira Nunes MDC., De Abreu Ferrari T. C., Hay K., Le V., Page M., Poulin F., Sauve C., Serri K., Mercure C., Beaudoin J., Pibarot P., Sebag I. A., Rudski L. G., Ricafort G., Barsic B., Krajinovic V., Vargovic M., Lovric D., Reskovic-Luksic V., Vincelj J., Jaksic Jurinjak S., Yiannikourides V., Ioannides M., Pofaides C., Masoura V., Pudich J., Linhart A., Siranec M., Marek J., Blechova K., Kamenik M., Pelouch R., Coufal Z., Mikulica M., Griva M., Jancova E., Mikulcova M., Taborsky M., Precek J., Jecmenova M., Latal J., Widimsky J., Butta T., Machacek S., Vancata R., Spinar J., Holicka M., Pow Chon Long F., Anzules N., Bajana Carpio A., Largacha G., Penaherrera E., Moreira D., Mahfouz E., Elsafty E., Soliman A., Zayed Y., Aboulenein J., Abdel-Hay M., Almaghraby A., Abdelnaby M., Ahmed M., Hammad B., Saleh Y., Zahran H., Elgebaly O., Saad A., Ali M., Zeid A., El Sharkawy R., Al Kholy A., Doss R., Osama D., Rizk H., Elmogy A., Mishriky M., Assayag P., El Hatimi S., Hubert S., Casalta J. P., Gouriet F., Arregle F., Cammilleri S., Tessonnier L., Riberi A., Botelho-Nevers E., Gagneux-Brunon A., Pierrard R., Tulane C., Campisi S., Fuzellier J. F., Detoc M., Mehalla T., Boutoille D., Lecompte A. S., Lefebvre M., Pattier S., Al Habash O., Asseray-Madani N., Biron C., Brochard J., Caillon J., Cueff C., Le Tourneau T., Lecomte R., Magali Michel M. M., Orain J., Delarue S., Le Bras M., Faucher J. F., Aboyans V., Beeharry A., Durox H., Lacoste M., Magne J., Mohty D., David A., Pradel V., Sierra V., Neykova A., Bettayeb B., Elkentaoui S., Tzvetkov B., Landry G., Strady C., Ainine K., Baumard S., Brasselet C., Tassigny C., Valente-Pires V., Lefranc M., Hoen B., Lefevre B., Curlier E., Callier C., Fourcade N., Jobic Y., Ansard S., Le Berre R., Le Ven F., Pouliquen M. C., Prat G., Le Roux P., Bouchart F., Savoure A., Alarcon C., Chapuzet C., Gueit I., Tribouilloy C., Bohbot Y., Peugnet F., Gun M., Duval X., Lescure X., Ilic-Habensus E., Sadoul N., Selton-Suty C., Alla F., Goehringer F., Huttin O., Chevalier E., Garcia R., Le Marcis V., Tattevin P., Flecher E., Revest M., Chirouze C., Bouiller K., Hustache-Mathieu L., Klopfenstein T., Moreau J., Fournier D., Brunel A. S., Lim P., Ternacle J., Moussafeur A., Chavanet P., Piroth L., Salmon-Rousseau A., Buisson M., Mahy S., Martins C., Gohier S., Baumann F., Lebras S., Piper C., Guckel D., Borgermann J., Horstkotte D., Winkelmann E., Brockmeier B., Grey D., Nickenig G., Schueler R., Ozturk C., Stohr E., Hamm C., Walther T., Brandt R., Fruhauf A. C., Hartung C. T., Hellner C., Wild C., Becker M., Hamada S., Kaestner W., Stangl K., Knebel F., Baldenhofer G., Brecht A., Dreger H., Isner C., Pfafflin F., Stegemann M., Zahn R., Fraiture B., Kilkowski C., Karcher A. K., Klinger S., Tolksdorf H., Tousoulis D., Aggeli C., Sideris S., Venieri E., Sarri G., Tsiapras D., Armenis I., Koutsiari A., Floros G., Grassos C., Dragasis S., Rallidis L., Varlamos C., Michalis L., Naka K., Bechlioulis A., Kotsia A., Lakkas L., Pappas K., Papadopoulos C., Kiokas S., Lioni A., Misailidou S., Barbetseas J., Bonou M., Kapelios C., Tomprou I., Zerva K., Manolis A., Hamodraka E., Athanasiou D., Haralambidis G., Samaras H., Poulimenos L., Nagy A., Bartykowszki A., Gara E., Mungulmare K., Kasliwal R., Bansal M., Ranjan S., Bhan A., Kyavar M., Maleki M., Noohi Bezanjani F., Alizadehasl A., Boudagh S., Ghavidel A., Moradnejad P., Pasha H. R., Ghadrdoost B., Gilon D., Strahilevitz J., Wanounou M., Israel S., d'Agostino C., Colonna P., De Michele L., Fumarola F., Stante M., Marchionni N., Scheggi V., Alterini B., Del Pace S., Stefano P., Sparano C., Ruozi N., Tenaglia R., Muraru D., Limbruno U., Cresti A., Baratta P., Solari M., Giannattasio C., Moreo A., De Chiara B., Lopez Montero B., Musca F., Orcese C. A., Panzeri F., Spano F., Russo C. F., Alfieri O., De Bonis M., Chiappetta S., Del Forno B., Ripa M., Scarpellini P., Tassan Din C., Castiglioni B., Pasciuta R., Carletti S., Ferrara D., Guffanti M., Iaci G., Lapenna E., Nisi T., Oltolini C., Busnardo E., Pajoro U., Agricola E., Meneghin R., Schiavi D., Piscione F., Citro R., Benvenga R. M., Greco L., Soriente L., Radano I., Prota C., Bellino M., Di Vece D., Santini F., Salsano A., Olivieri G. M., Turrini F., Messora R., Tondi S., Olaru A., Agnoletto V., Grassi L., Leonardi C., Sansoni S., Del Ponte S., Actis Dato G. M., De Martino A., Ohte N., Kikuchi S., Wakami K., Aonuma K., Seo Y., Ishizu T., Machino-Ohtsuka T., Yamamoto M., Iida N., Nakajima H., Nakagawa Y., Izumi C., Amano M., Miyake M., Takahashi K., Shiojima I., Miyasaka Y., Maeba H., Suwa Y., Taniguchi N., Tsujimoto S., Kitai T., Ota M., Yuda S., Sasaki S., Hagiwara N., Yamazaki K., Ashihara K., Arai K., Saitou C., Saitou S., Suzuki G., Shibata Y., Watanabe N., Nishino S., Ashikaga K., Kuriyama N., Mahara K., Okubo T., Fujimaki H., Shitan H., Yamamoto H., Abe K., Terada M., Takanashi S., Sata M., Yamada H., Kusunose K., Saijo Y., Seno H., Yuichiro O., Onishi T., Sera F., Nakatani S., Mizuno H., Sengoku K., Park S. W., Eun Kyoung K., Ga Yeon L., Hwang J. W., Jin-Oh C., Park S. J., Sang-Chol L., Sung-A C., Jang S. Y., Heo R., Lee S., Song J. M., Jung E., Plisiene J., Dambrauskaite A., Gruodyte G., Jonkaitiene R., Mizariene V., Atkocaityte J., Zvirblyte R., Codreanu A., Staub T., Michaux C., De la Vega ECL., Jacobs-Orazi L., Mallia Azzopardi C., Xuereb R. G., Piscopo T., Farrugia J., Fenech M., Pllaha E., Vella C., Borg D., Casha R., Grib L., Raevschi E., Grejdieru A., Kravcenco D., Prisacari E., Samohvalov E., Samohvalov S., Sceglova N., Panfile E., Cardaniuc L., Corcea V., Feodorovici A., Gaina V., Girbu L., Jimbei P., Balan G., Cardaniuc I., Benesco I., Marian V., Sumarga N., Bozovic B., Bulatovic N., Lakovic P., Music L., Budde R., Wahadat A., Gamela T., Meijers T., Van Melle J. P., Deursen V. M., Crijns H. J., Bekkers S. C., Cheriex E. C., Gilbers M., Kietselaer B. L., Knackstedt C., Lorusso R., Schalla S., Streukens S. A., Chamuleau S., Cramer M. J., Teske A., Van der Spoel T., Wind A., Lokhorst J., Liesbek O., Van Heusden H., Tanis W., Van der Bilt I., Vriend J., De Lange-van Bruggen H., Karijodikoro E., Riezebos R., van Dongen E., Schoep J., Stolk V., Offstad J. T., Beitnes J. O., Helle-Valle T., Skulstad H., Skardal R., Qamar N., Furnaz S., Ahmed B., Butt M. H., Khanzada M. F., Saghir T., Wahid A., Hryniewiecki T., Szymanski P., Marzec K., Misztal-Ogonowska M., Kosmala W., Przewlocka-Kosmala M., Rojek A., Woznicka K., Zachwyc J., Lisowska A., Kaminska M., Kasprzak J. D., Kowalczyk E., Strzecka D. F., Wejner-Mik P., Trabulo M., Freitas P., Ranchordas S., Rodrigues G., Pinto P., Queiros C., Azevedo J., Marques L., Seabra D., Branco L., Cruz M., Galrinho A., Moreira R., Rio P., Timoteo A. T., Selas M., Carmelo V., Duque Neves B., Pereira H., Guerra A., Marques A., Pintassilgo I., Tomescu M. C., Trofenciuc N. M., Andor M., Bordejevic A., Branea H. S., Caruntu F., Velcean L. A., Mavrea A., Onel M. F., Parvanescu T., Pop D., Pop-Moldovan A. L., Puticiu M. I., Cirin L., Citu I. M., Cotoraci C. A., Darabantiu D., Farcas R., Marincu I., Ionac A., Cozma D., Mornos C., Goanta F., Popescu I., Beyer R., Mada R., Rancea R., Tomoaia R., Rosianu H., Stanescu C., Kobalava Z., Karaulova J., Kotova E., Milto A., Pisaryuk A., Povalyaev N., Sorokina M., Alrahimi J., Elshiekh A., Jamiel A., Ahmed A., Attia N., Putnikovic B., Dimic A., Ivanovic B., Matic S., Trifunovic D., Petrovic J., Kosevic D., Stojanovic I., Petrovic I., Dabic P., Milojevic P., Srdanovic I., Susak S., Velicki L., Vulin A., Kovacevic M., Redzek A., Stefanovic M., Yeo T. C., Kong W. K., Poh K. K., Vilacosta I., Ferrera C., Olmos C., Abd El-Nasser M., Calvo Iglesias F., Blanco-Gonzalez E., Bravo Amaro M., Lopez-Rodriguez E., Lugo Adan J., Germinas A. N., Pazos-Lopez P., Pereira Loureiro M., Perez M. T., Raposeiras-Roubin S., Rasheed Yas S., Suarez-Varela M. M., Vasallo Vidal F., Garcia-Dorado D., Fernandez-Hidalgo N., Gonzalez-Alujas T., Lozano J., Maisterra O., Pizzi N., Rios R., Bayes-Genis A., Pedro Botet L., Vallejo N., Llibre C., Mateu L., Nunez R., Quesada D., Berastegui E., Bosch Portell D., Aboal Vinas J., Albert Bertran X., Brugada Tarradellas R., Loma-Osorio Ricon P., Tiron de Llano C., Arnau M. A., Bel A., Blanes M., Osa A., Anguita M., Carrasco F., Castillo J. C., Zamorano J. L., Moya Mur J. L., Alvaro M., Fernandez-Golfin C., Monteagudo J. M., Navas Elorza E., Farinas Alvarez M. C., Aguero Balbin J., Zarauza J., Gutierrez-Diez J. F., Arminanzas C., Arnaiz de Las Revillas F., Arnaiz Garcia A., Cobo Belaustegui M., Fernandez Sampedro M., Gutierrez Cuadra M., Garcia Cuello L., Gonzalez Rico C., Rodriguez-Alvarez R., Goikoetxea J., Montejo M., Miro J. M., Almela M., Ambrosioni J., Moreno A., Quintana E., Sandoval E., Tellez A., Tolosana J. M., Vidal B., Falces C., Fuster D., Garcia-de-la-Maria C., Hernandez-Meneses M., Llopis J., Marco F., Ruiz-Zamora I., Bardaji Ruiz A., Sanz Girgas E., Garcia-Pardo G., Guillen Marzo M., Rodriguez Oviedo A., Villares Jimenez A., Abid L., Hammami R., Kammoun S., Mourali M. S., Ben Hlima M., Boudiche S., Ouali S., Zakhama L., Antit S., Slama I., Gulel O., Sahin M., Karacaglar E., Kucukoglu S., Cetinarslan O., Yasar U. S., Canpolat U., Mutlu B., Atas H., Dervishova R., Ileri C., Alhashmi J., Tahir J., Zarger P., Baslib F., Woldman S., Menezes L., Primus C., Uppal R., Bvekerwa I., Chandrasekaran B., Kopanska A., Chambers J., Hancock J., Klein J., Rajani R., Ursi M. P., Cannata S., Dworakowski R., Fife A., Breeze J., Browne-Morgan M., Gunning M., Streather S., Asch F. M., Zemedkun M., Alyavi B., Uzokov J., Habib, G, Erba, P, Iung, B, Donal, E, Cosyns, B, Laroche, C, Popescu, B, Prendergast, B, Tornos, P, Sadeghpour, A, Oliver, L, Vaskelyte, J, Sow, R, Axler, O, Maggioni, A, Lancellotti, P, Gale, C, Beleslin, B, Budaj, A, Chioncel, O, Dagres, N, Danchin, N, Emberson, J, Erlinge, D, Glikson, M, Gray, A, Kayikcioglu, M, Nagy, V, Nedoshivin, A, Petronio, A, Roos-Hesselink, J, Wallentin, L, Zeymer, U, Andarala, M, Berle, C, Brunel-Lebecq, A, Fiorucci, E, Missiamenou, V, Taylor, C, Ali Tatar-Chentir, N, Al-Mallah, M, Astrom Aneq, M, Athanassopoulos, G, Badano, L, Benyoussef, S, Calderon Aranda, E, Cardim, N, Chan, K, Cruz, I, Edvardsen, T, Goliasch, G, Hagendorff, A, Hristova, K, Kamp, O, Kang, D, Kong, W, Matskeplishvili, S, Meshaal, M, Mirocevic, M, Neskovic, A, Pazdernik, M, Plonska-Gosciniak, E, Raissouni, M, Ronderos, R, Sade, L, Sambola, A, Sengupta, S, Separovic-Hanzevacki, J, Takeuchi, M, Tucay, E, Tude Rodrigues, A, Varga, A, Yamagata, K, 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Abstract

Aims: The EURO-ENDO registry aimed to study the management and outcomes of patients with infective endocarditis (IE). Methods and results: Prospective cohort of 3116 adult patients (2470 from Europe, 646 from non-ESC countries), admitted to 156 hospitals in 40 countries between January 2016 and March 2018 with a diagnosis of IE based on ESC 2015 diagnostic criteria. Clinical, biological, microbiological, and imaging [echocardiography, computed tomography (CT) scan, 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT)] data were collected. Infective endocarditis was native (NVE) in 1764 (56.6%) patients, prosthetic (PVIE) in 939 (30.1%), and device-related (CDRIE) in 308 (9.9%). Infective endocarditis was community-acquired in 2046 (65.66%) patients. Microorganisms involved were staphylococci in 1085 (44.1%) patients, oral streptococci in 304 (12.3%), enterococci in 390 (15.8%), and Streptococcus gallolyticus in 162 (6.6%). 18F-fluorodeoxyglucose positron emission tomography/computed tomography was performed in 518 (16.6%) patients and presented with cardiac uptake (major criterion) in 222 (42.9%) patients, with a better sensitivity in PVIE (66.8%) than in NVE (28.0%) and CDRIE (16.3%). Embolic events occurred in 20.6% of patients, and were significantly associated with tricuspid or pulmonary IE, presence of a vegetation and Staphylococcus aureus IE. According to ESC guidelines, cardiac surgery was indicated in 2160 (69.3%) patients, but finally performed in only 1596 (73.9%) of them. In-hospital death occurred in 532 (17.1%) patients and was more frequent in PVIE. Independent predictors of mortality were Charlson index, creatinine > 2 mg/dL, congestive heart failure, vegetation length > 10 mm, cerebral complications, abscess, and failure to undertake surgery when indicated. Conclusion: Infective endocarditis is still a life-threatening disease with frequent lethal outcome despite profound changes in its clinical, microbiolog

Published
2019

17. The ESC-EORP EURO-ENDO (European Infective Endocarditis) registry

Author

Habib, G, Lancellotti, P, Erba, P, Sadeghpour, A, Meshaal, M, Sambola, A, Furnaz, S, Citro, R, Ternacle, J, Donal, E, Cosyns, B, Popescu, B, Iung, B, Prendergast, B, Laroche, C, Tornos, P, Pazdernik, M, Maggioni, A, Gale, C, Ali Tatar-Chentir, N, Al-Mallah, M, Astrom Aneq, M, Athanassopoulos, G, Badano, L, Benyoussef, S, Calderon Aranda, E, Cardim, N, Chan, K, Cruz, I, Edvardsen, T, Goliasch, G, Hagendorff, A, Hristova, K, Kamp, O, Kang, D, Kong, W, Matskeplishvili, S, Mirocevic, M, Neskovic, A, Plonska-Gosciniak, E, Raissouni, M, Ronderos, R, Sade, L, Sengupta, S, Separovic-Hanzevacki, J, Takeuchi, M, Tucay, E, Tude Rodrigues, A, Varga, A, Vaskelyte, J, Yamagata, K, Yiangou, K, Zaky, H, Granada, I, Mahia, M, Ressi, S, Nacinovich, F, Iribarren, A, Fernandez Oses, P, Avegliano, G, Filipini, E, Obregon, R, Bangher, M, Dho, J, Cartasegna, L, Plastino, M, Novas, V, Shigel, C, Reyes, G, De Santos, M, Gastaldello, N, Granillo Fernandez, M, Potito, M, Streitenberger, G, Velazco, P, Casabe, J, Cortes, C, Guevara, E, Salmo, F, Seijo, M, Weidinger, F, Heger, M, Brooks, R, Stollberger, C, Ho, C, Perschy, L, Puskas, L, Binder, C, Rosenhek, R, Schneider, M, Winter, M, Hoffer, E, Melissopoulou, M, Lecoq, E, Legrand, D, Jacquet, S, Massoz, M, Pierard, L, Marchetta, S, Dulgheru, R, Emal, C, Oury, C, Droogmans, S, Kerkhove, D, Plein, D, Soens, L, Weytjens, C, Motoc, A, Roosens, B, Lemoine, I, Rodrigus, I, Paelinck, B, Amsel, B, Unger, P, Konopnicki, D, Beauloye, C, Pasquet, A, Vanoverschelde, J, Pierard, S, Vancraeynest, D, Sinnaeve, F, Andrade, J, Staszko, K, Dos Santos Monteiro, R, Miglioranza, M, Shuha, D, Alcantara, M, Cravo, V, Fazzio, L, Felix, A, Iso, M, Musa, C, Siciliano, A, Villaca Filho, F, Rodrigues, A, Vilela, F, Braga, J, Silva, R, Rodrigues, D, Silva, L, Morhy, S, Fischer, C, Vieira, M, Afonso, T, Abreu, J, Falcao, S, Moises, V, Gouvea, A, Mancuso, F, Souza, A, Silva, C, Joao, G, Abboud, C, Bellio De Mattos Barretto, R, Ramos, A, Arnoni, R, Assef, J, Della Togna, D, 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T., Hellner C., Wild C., Becker M., Hamada S., Kaestner W., Stangl K., Knebel F., Baldenhofer G., Brecht A., Dreger H., Isner C., Pfafflin F., Stegemann M., Zahn R., Fraiture B., Kilkowski C., Karcher A. -K., Klinger S., Tolksdorf H., Tousoulis D., Aggeli C., Sideris S., Venieri E., Sarri G., Tsiapras D., Armenis I., Koutsiari A., Floros G., Grassos C., Dragasis S., Rallidis L., Varlamos C., Michalis L., Naka K., Bechlioulis A., Kotsia A., Lakkas L., Pappas K., Papadopoulos C., Kiokas S., Lioni A., Misailidou S., Barbetseas J., Bonou M., Kapelios C., Tomprou I., Zerva K., Manolis A., Hamodraka E., Athanasiou D., Haralambidis G., Samaras H., Poulimenos L., Nagy A., Bartykowszki A., Gara E., Mungulmare K., Kasliwal R., Bansal M., Ranjan S., Bhan A., Kyavar M., Maleki M., Noohi Bezanjani F., Alizadehasl A., Boudagh S., Ghavidel A., Moradnejad P., Pasha H. R., Ghadrdoost B., Gilon D., Strahilevitz J., Wanounou M., Israel S., D'Agostino C., Colonna P., Michele L. D., Fumarola F., Stante M., Marchionni N., Scheggi V., Alterini B., Del Pace S., Stefano P., Sparano C., Ruozi N., Tenaglia R., Muraru D., Limbruno U., Cresti A., Baratta P., Solari M., Giannattasio C., Moreo A., Chiara B. D., Lopez Montero B., Musca F., Orcese C. A., Panzeri F., Spano F., Russo C. F., Alfieri O., Bonis M. D., Chiappetta S., Del Forno B., Ripa M., Scarpellini P., Tassan Din C., Castiglioni B., Pasciuta R., Carletti S., Ferrara D., Guffanti M., Iaci G., Lapenna E., Nisi T., Oltolini C., Busnardo E., Pajoro U., Agricola E., Meneghin R., Schiavi D., Piscione F., Benvenga R. M., Greco L., Soriente L., Radano I., Prota C., Bellino M., Vece D. D., Santini F., Salsano A., Olivieri G. M., Turrini F., Messora R., Tondi S., Olaru A., Agnoletto V., Grassi L., Leonardi C., Sansoni S., Del Ponte S., Actis Dato G. M., Martino A. D., Ohte N., Kikuchi S., Wakami K., Aonuma K., Seo Y., Ishizu T., MacHino-Ohtsuka T., Yamamoto M., Iida N., Nakajima H., Nakagawa Y., Izumi C., Amano M., Miyake M., Takahashi K., Shiojima I., Miyasaka Y., Maeba H., Suwa Y., Taniguchi N., Tsujimoto S., Kitai T., Ota M., Yuda S., Sasaki S., Hagiwara N., Yamazaki K., Ashihara K., Arai K., Saitou C., Saitou S., Suzuki G., Shibata Y., Watanabe N., Nishino S., Ashikaga K., Kuriyama N., Mahara K., Okubo T., Fujimaki H., Shitan H., Yamamoto H., Abe K., Terada M., Takanashi S., Sata M., Yamada H., Kusunose K., Saijo Y., Seno H., Yuichiro O., Onishi T., Sera F., Nakatani S., Mizuno H., Sengoku K., Park S. W., Eun Kyoung K., Ga Yeon L., Hwang J. -W., Jin-Oh C., Park S. -J., Sang-Chol L., Sung-A C., Jang S. Y., Heo R., Lee S., Song J. -M., Jung E., Plisiene J., Dambrauskaite A., Gruodyte G., Jonkaitiene R., Mizariene V., Atkocaityte J., Zvirblyte R., Sow R., Codreanu A., Staub T., Michaux C., De La Vega E. C. L., Jacobs-Orazi L., Mallia Azzopardi C., Xuereb R. G., Piscopo T., Farrugia J., Fenech M., Pllaha E., Vella C., Borg D., Casha R., Grib L., Raevschi E., Grejdieru A., Kravcenco D., Prisacari E., Samohvalov E., Samohvalov S., Sceglova N., Panfile E., Cardaniuc L., Corcea V., Feodorovici A., Gaina V., Girbu L., Jimbei P., Balan G., Cardaniuc I., Benesco I., Marian V., Sumarga N., Bozovic B., Bulatovic N., Lakovic P., Music L., Budde R., Wahadat A., Gamela T., Meijers T., Van Melle J. P., Deursen V. M., Crijns H. J., Bekkers S. C., Cheriex E. C., Gilbers M., Kietselaer B. L., Knackstedt C., Lorusso R., Schalla S., Streukens S. A., Chamuleau S., Cramer M. -J., Teske A., Van Der Spoel T., Wind A., Lokhorst J., Liesbek O., Van Heusden H., Tanis W., Van Der Bilt I., Vriend J., Lange-Van Bruggen H. D., Karijodikoro E., Riezebos R., Van Dongen E., Schoep J., Stolk V., Offstad J. T., Beitnes J. O., Helle-Valle T., Skulstad H., Skardal R., Qamar N., Ahmed B., Butt M. H., Khanzada M. F., Saghir T., Wahid A., Hryniewiecki T., Szymanski P., Marzec K., Misztal-Ogonowska M., Kosmala W., Przewlocka-Kosmala M., Rojek A., Woznicka K., Zachwyc J., Lisowska A., Kaminska M., Kasprzak J. D., Kowalczyk E., Strzecka D. F., Wejner-Mik P., Trabulo M., Freitas P., Ranchordas S., Rodrigues G., Pinto P., Queiros C., Azevedo J., Marques L., Seabra D., Branco L., Cruz M., Galrinho A., Moreira R., Rio P., Timoteo A. T., Selas M., Carmelo V., Duque Neves B., Pereira H., Guerra A., Marques A., Pintassilgo I., Tomescu M. C., Trofenciuc N. -M., Andor M., Bordejevic A., Branea H. S., Caruntu F., Velcean L. A., Mavrea A., Onel M. F., Parvanescu T., Pop D., Pop-Moldovan A. L., Puticiu M. I., Cirin L., Citu I. M., Cotoraci C. A., Darabantiu D., Farcas R., Marincu I., Ionac A., Cozma D., Mornos C., Goanta F., Popescu I., Beyer R., Mada R., Rancea R., Tomoaia R., Rosianu H., Stanescu C., Kobalava Z., Karaulova J., Kotova E., Milto A., Pisaryuk A., Povalyaev N., Sorokina M., Alrahimi J., Elshiekh A., Jamiel A., Ahmed A., Attia N., Putnikovic B., Dimic A., Ivanovic B., Matic S., Trifunovic D., Petrovic J., Kosevic D., Stojanovic I., Petrovic I., Dabic P., Milojevic P., Srdanovic I., Susak S., Velicki L., Vulin A., Kovacevic M., Redzek A., Stefanovic M., Yeo T. C., Kong W. K. F., Poh K. K., Vilacosta I., Ferrera C., Olmos C., Abd El-Nasser M., Calvo Iglesias F., Blanco-Gonzalez E., Bravo Amaro M., Lopez-Rodriguez E., Lugo Adan J., Germinas A. N., Pazos-Lopez P., Pereira Loureiro M., Perez M. T., Raposeiras-Roubin S., Rasheed Yas S., Suarez-Varela M. -M., Vasallo Vidal F., Garcia-Dorado D., Fernandez-Hidalgo N., Gonzalez-Alujas T., Lozano J., Maisterra O., Pizzi N., Rios R., Bayes-Genis A., Pedro Botet L., Vallejo N., Llibre C., Mateu L., Nunez R., Quesada D., Berastegui E., Bosch Portell D., Aboal Vinas J., Albert Bertran X., Brugada Tarradellas R., Loma-Osorio Ricon P., Tiron De Llano C., Arnau M. A., Bel A., Blanes M., Osa A., Anguita M., Carrasco F., Castillo J. C., Zamorano J. L., Moya Mur J. L., Alvaro M., Fernandez-Golfin C., Monteagudo J. M., Navas Elorza E., Farinas Alvarez M. C., Aguero Balbin J., Zarauza J., Gutierrez-Diez J. F., Arminanzas C., Arnaiz De Las Revillas F., Arnaiz Garcia A., Cobo Belaustegui M., Fernandez Sampedro M., Gutierrez Cuadra M., Garcia Cuello L., Gonzalez Rico C., Rodriguez-Alvarez R., Goikoetxea J., Montejo M., Miro J. M., Almela M., Ambrosioni J., Moreno A., Quintana E., Sandoval E., Tellez A., Tolosana J. M., Vidal B., Falces C., Fuster D., Garcia-De-La-Maria C., Hernandez-Meneses M., Llopis J., Marco F., Ruiz-Zamora I., Bardaji Ruiz A., Sanz Girgas E., Garcia-Pardo G., Guillen Marzo M., Rodriguez Oviedo A., Villares Jimenez A., Abid L., Hammami R., Kammoun S., Mourali M. S., Ben Hlima M., Boudiche S., Ouali S., Zakhama L., Antit S., Slama I., Gulel O., Sahin M., Karacaglar E., Kucukoglu S., Cetinarslan O., Yasar U. S., Canpolat U., Mutlu B., Atas H., Dervishova R., Ileri C., Alhashmi J., Tahir J., Zarger P., Baslib F., Woldman S., Menezes L., Primus C., Uppal R., Bvekerwa I., Chandrasekaran B., Kopanska A., Chambers J., Hancock J., Klein J., Rajani R., Ursi M. P., Cannata S., Dworakowski R., Fife A., Breeze J., Browne-Morgan M., Gunning M., Streather S., Asch F. 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M., Vidal B., Falces C., Fuster D., Garcia-De-La-Maria C., Hernandez-Meneses M., Llopis J., Marco F., Ruiz-Zamora I., Bardaji Ruiz A., Sanz Girgas E., Garcia-Pardo G., Guillen Marzo M., Rodriguez Oviedo A., Villares Jimenez A., Abid L., Hammami R., Kammoun S., Mourali M. S., Ben Hlima M., Boudiche S., Ouali S., Zakhama L., Antit S., Slama I., Gulel O., Sahin M., Karacaglar E., Kucukoglu S., Cetinarslan O., Yasar U. S., Canpolat U., Mutlu B., Atas H., Dervishova R., Ileri C., Alhashmi J., Tahir J., Zarger P., Baslib F., Woldman S., Menezes L., Primus C., Uppal R., Bvekerwa I., Chandrasekaran B., Kopanska A., Chambers J., Hancock J., Klein J., Rajani R., Ursi M. P., Cannata S., Dworakowski R., Fife A., Breeze J., Browne-Morgan M., Gunning M., Streather S., Asch F. M., Zemedkun M., Alyavi B., and Uzokov J.

Abstract

Aims: The European Society of Cardiology (ESC) EURObservational Research Programme (EORP) European Endocarditis (EURO-ENDO) registry aims to study the care and outcomes of patients diagnosed with infective endocarditis (IE) and compare findings with recommendations from the 2015 ESC Clinical Practice Guidelines for the management of IE and data from the 2001 Euro Heart Survey. Methods and results: Patients (n = 3116) aged over 18 years with a diagnosis of IE based on the ESC 2015 IE diagnostic criteria were prospectively identified between 1 January 2016 and 31 March 2018. Individual patient data were collected across 156 centres and 40 countries. The primary endpoint is all-cause mortality in hospital and at 1 year. Secondary endpoints are 1-year morbidity (all-cause hospitalization, any cardiac surgery, and IE relapse), the clinical, epidemiological, microbiological, and therapeutic characteristics of patients, the number and timing of non-invasive imaging techniques, and adherence to recommendations as stated in the 2015 ESC Clinical Practice Guidelines for the management of IE. Conclusion: EURO-ENDO is an international registry of care and outcomes of patients hospitalized with IE which will provide insights into the contemporary profile and management of patients with this challenging disease

Published
2019

18. TRY plant trait database – enhanced coverage and open access

Author

Kattge, J., Bonisch, G., Diaz, S., Lavorel, S., Prentice, I. C., Leadley, P., Tautenhahn, S., Werner, G. D. A., Aakala, T., Abedi, M., Acosta, A. T. R., Adamidis, G. C., Adamson, K., Aiba, M., Albert, C. H., Alcantara, J. M., Alcazar, C C., Aleixo, I., Ali, H., Amiaud, B., Ammer, C., Amoroso, M. M., Anand, M., Anderson, C., Anten, N., Antos, J., Apgaua, D. M. G., Ashman, T. L., Asmara, D. H., Asner, G. P., Aspinwall, M., Atkin, O., Aubin, I., Baastrup-Spohr, L., Bahalkeh, K., Bahn, M., Baker, T., Baker, W. J., Bakker, J. P., Baldocchi, D., Baltzer, J., Banerjee, A., Baranger, A., Barlow, J., Barneche, D. R., Baruch, Z., Bastianelli, D., Battles, J., Bauerle, W., Bauters, M., Bazzato, E., Beckmann, M., Beeckman, H., Beierkuhnlein, C., Bekker, R., Belfry, G., Belluau, M., Beloiu, M., Benavides, R., Benomar, L., Berdugo-Lattke, M. L., Berenguer, E., Bergamin, R., Bergmann, J., Bergmann Carlucci, M., Berner, L., Bernhardt Romermann, M., Bigler, C., Bjorkman, A. D., Blackman, C., Blanco, C., Blonder, B., Blumenthal, D., Bocanegra Gonzalez, K. T., Boeckx, P., Bohlman, S., Bohning Gaese, K., Boisvert Marsh, L., Bond, W., Bond-Lamberty, B., Boom, A., Boonman, C. C. F., Bordin, K., Boughton, E. H., Boukili, V., Bowman, D. M. J. S., Bravo, S., Brende, l M. R., Broadley, M. R., Brown, K. A., Bruelheide, H., Brumnich, F., Bruun, H. H., Bruy, D., Buchanan, S. W., Bucher, S. F., Buchmann, N., Buitenwerf, R., Bunker, D. E., Burge, r J., Burrascano, S., Burslem, D. F. R. P., Butterfield, B. J., Byun, C., Marques, M., Scalon, M. C., Caccianiga, M., Cadotte, M., Cailleret, M., Camac, J., Camarero, J. J., Campany, C., Campetella, G., Campos, J. A., Cano Arboleda, L., Canullo, R., Carbognani, M., Carvalho, F., Casanoves, F., Castagneyrol, B., Catford, J. A., Cavender Bares, J., Cerabolini, B. E. L., Cervellini, M., Chacon Madrigal, E., Chapin, K., Chapin, F. S., Chelli, S., Chen, S. C., Chen, A., Cherubini, P., Chianucci, F., Choat, B., Chung, K. S., Chytry, M., Ciccarelli, D., Coll, L., Collins, C. G., Conti, L., Coomes, D., Cornelissen, J. H. C., Cornwell, W. K., Corona, P., Coyea, M., Craine, J., Craven, D., Cromsigt, J. P. G. M., Csecserits, A., Cufar, K., Cuntz, M., da Silva, A. C., Dahlin, K. M., Dainese, M., Dalke, I., Dalle Fratte, M., Dang Le, A. T., Danihelka, J., Dannoura, M., Dawson, S., de Beer, A. J., De Frutos, A., De Long, J. R., Dechant, B., Delagrange, S., Delpierre, N., Derroire, G., Dias, A. S., Diaz Toribio, M. H., Dimitrakopoulos, P. G., Dobrowolski, M., Doktor, D., Drevojan, P., Dong, N., Dransfield, J., Dressler, S., Duarte, L., Ducouret, E., Dullinger, S., Durka, W., Duursma, R., Dymova, O., E- Vojtko, A., Eckstein, R. L., Ejtehadi, H., Elser, J., Emilio, T., Engemann, K., Erfanian, M. B., Erfmeier, A., Esquivel Muelbert, A., Esser, G., Estiarte, M., Domingues, T. F., Fagan, W. F., Fagundez, J., Falster, D. S., Fan, Y., Fang, J., Farris, E., Fazlioglu, F., Feng, Y., Fernandez, Mendez, Ferrara, C., Ferreira, J., Fidelis, A., Finegan, B., Firn, J., Flowers, T. J., Flynn, D. F. B., Fontana, V., Forey, E., Forgiarini, C., Francois, L., Frangipani, M., Frank, D., Frenette Dussault, C., Freschet, G. T., Fry, E. L., Fyllas, N. M., Mazzochini, G. G., Gachet, S., Gallagher, R., Ganade, G., Ganga, F., Garcia Palacios, P., Gargaglione, V., Garnier, E., Garrido, J. L., de Gasper, A. L., Gea Izquierdo, G., Gibson, D., Gillison, A. N., Giroldo, A., Glasenhardt, M. C., Gleason, S., Gliesch, M., Goldberg, E., Goldel, B., Gonzalez Akre, E., Gonzalez Andujar, J. L., Gonzalez Melo, A., Gonzalez Robles, A., Graae, B. J., Granda, E., Graves, S., Green, W. A., Gregor, T., Gross, N., Guerin, G. R., Gunther, A., Gutierrez, A. G., Haddock, L., Haines, A., Hall, J., Hambuckers, A., Han, W., Harrison, S. P., Hattingh, W., Hawes, J. E., He, T., He, P., Heberling, J. M., Helm, A., Hempel, S., Hentschel, J., Herault, B., Heres, A. M., Herz, K., Heuertz, M., Hickler, T., Hietz, P., Higuchi, P., Hipp, A. L., Hirons, A., Hock, M., Hogan, J. A., Holl, K., Honnay, O., Hornstein, D., Hou, E., Hough Snee, N., Hovstad, K. A., Ichie, T., Igic, B., Illa, E., Isaac, M., Ishihara, M., Ivanov, L., Ivanova, L., Iversen, C. M., Izquierdo, J., Jackson, R. B., Jackson, B., Jactel, H., Jagodzinsk, A. M., Jandt, U., Jansen, S., Jenkins, T., Jentsch, A., Jespersen, J. R. P., Jiang, G. F., Johansen, J. L., Johnson, D., Jokela, E. J., Joly, C. A., Jordan, G. J., Joseph, G. S., Junaedi, D., Junker, R. R., Justes, E., Kabzems, R., Kane, J., Kaplan, Z., Kattenborn, T., Kavelenova, L., Kearsley, E., Kempel, A., Kenzo, T., Kerkhoff, A., Khalil, M. I., Kinlock, N. L., Kissling, W. D., Kitajima, K., Kitzberger, T., Kjoller, R., Klein, T., Kleyer, M., Klimesova, J., Klipel, J., Kloeppel, B., Klotz, S., Knops, J. M. H., Kohyama, T., Koike, F., Kollmann, J., Komac, B., Komatsu, K., Konig, C., Kraft, N. J. B., Kramer, K., Kreft, H., Kuhn, I., Kumarathune, D., Kuppler, J., Kurokawa, H., Kurosawa, Y., Kuyah, S., Laclau, J. P., Lafleur, B., Lallai, E., Lamb, E., Lamprecht, A., Larkin, D. J., Laughlin, D., Le Bagousse Pinguet, Y., le Maire, G., le Roux, P. C., le Roux, E., Lee, T., Lens, F., Lewis, S. L., Lhotsky, B., Li, Y., Li, X., Lichstein, J. W., Liebergesell, M., Lim, J. Y., Lin, Y. S., Linares, Y. C., Liu, C., Liu, D., Liu, U., Livingstone, S., Llusia, J., Lohbeck, M., Lopez Garcia, A., Lopez Gonzalez, G., Lososov, a Z., Louault, F., Lukacs, B. A., Lukes, P., Luo, Y., Lussu, M., Ma, S., Maciel Rabelo Pereira, C., Mack, M., Maire, V., Makela, A., Makinen, H., Malhado, A. C. M., Mallik, A., Manning, P., Manzoni, S., Marchetti, Z., Marchino, L., Marcilio Silva, V., Marcon, E., Marignani, M., Markesteijn, L., Martin, A., Martinez Garza, C., Martinez Vilalta, J., Maskova, T., Mason, K., Mason, N., Massad, T. J., Masse, J., Mayrose, I., Mccarthy, J., Mccormack, M. L., Mcculloh, K., Mcfadden, I., Mcgill, B. J., Mcpartland, M. Y., Medeiros, J., Medlyn, B., Meerts, P., Mehrabi, Z., Meir, P., Melo, F., P. L., Mencuccini, M., Meredieu, C., Messier, J., Meszaros, I., Metsaranta, J., Michaletz, S. T., Michelaki, C., Migalina, S., Milla, R., Miller, J., E. D., Minden, V., Ming, R., Mokany, K., Moles, A. T., Molnar, A., Molofsky, J., Molz, M., Montgomery, R. A., Monty, A., Moravcova, L., Moreno Martinez, A., Moretti, M., Mori, A. S., Mori, S., Morris, D., Morrison, J., Mucina, L., Mueller, S., Muir, C. D., Muller, S. C., Munoz, F., Myers Smith, I. H., Myster, R. W., Nagano, M., Naidu, S., Narayanan, A., Natesan, B., Negoita, L., Nelson, A. S., Neuschulz, E. L., Ni, J., Niedrist, G., Nieto, J., Niinemets, U., Nolan, R., Nottebrock, H., Nouvellon, Y., Novakovskiy, A., Nystuen, K. O., O'Grady, A., O'Hara, K., O'Reilly Nugent, A., Oakley, S., Oberhuber, W., Ohtsuka, T., Oliveira, R., Ollerer, K., Olson, M. E., Onipchenko, V., Onoda, Y., Onstein, R. E., Ordonez, J. C., Osada, N., Ostonen, I., Ottaviani, G., Otto, S., Overbeck, G. E., Ozinga, W. A., Pahl, A. T., Paine, C. E. T., Pakeman, R. J., Papageorgiou, A. C., Parfionova, E., Partel, M., Patacca, M., Paula, S., Paule, J., Pauli, H., Pausas, J., Peco, B., Penuelas, J., Perea, A., Peri, P. L., Petisco Souza, A. C., Petraglia, A., Petritan, A. M., Phillips, O. L., Pierce, S., Pillar, V. D., Pisek, J., Pomogaybin, A., Poorter, H., Portsmuth, A., Poschlod, P., Potvin, C., Pounds, D., Powell, A., Power, S. A., Prinzing, A., Puglielli, G., Pysek, P., Raevel, V., Rammig, A., Ransijn, J., Ray, C. A., Reich, P. B., Reichstein, M., Reid, D. E. B., Rejou Mechain, M., de Dios, V. R., Ribeiro, S., Richardson, S., Riibak, K., Rillig, M. C., Riviera, F., Robert, E. M. R., Roberts, S., Robroek, B., Roddy, A., Rodrigues, A. V., Rogers, A., Rollinson, E., Rolo, V., Romermann, C., Ronzhina, D., Roscher, C., Rosell, J. A., Rosenfield, M. F., Rossi, C., Roy, D. B., Royer Tardif, S., Ruger, N., Ruiz Peinado, R., Rumpf, S. B., Rusch, G. M., Ryo, M., Sack, L., Saldana, A., Salgado Negret, B., Salguero Gomez, R., Santa Regina, I., Santacruz Garcia, A. C., Santos, J., Sardans, J., Schamp, B., Scherer Lorenzen, M., Schleuning, M., Schmid, B., Schmidt, M., Schmitt, S., Schneider, J. V., Schowanek, S. D., Schrader, J., Schrodt, F., Schuldt, B., Schurr, F., Selaya Garvizu, G., Semchenko, M., Seymour, C., Sfair, J. C., Sharpe, J. M., Sheppard, C. S., Sheremetiev, S., Shiodera, S., Shipley, B., Shovon, T. A., Siebenkas, A., Sierra, C., Silva, V., Silva, M., Sitzia, T., Sjoman, H., Slot, M., Smith, N. G., Sodhi, D., Soltis, P., Soltis, D., Somers, B., Sonnier, G., Sorensen, M. V., Sosinski, E. E., Soudzilovskaia, N. A., Souza, A. F., Spasojevic, M., Sperandii, M. G., Stan, A. B., Stegen, J., Steinbauer, K., Stephan, J. G., Sterck, F., Stojanovic, D. B., Strydom, T., Suarez, M. L., Svenning, J. C., Svitkova, I., Svitok, M., Svoboda, M., Swaine, E., Swenson, N., Tabarelli, M., Takagi, K., Tappeiner, U., Tarifa, R., Tauugourdeau, S., Tavsanoglu, C., te Beest, M., Tedersoo, L., Thiffault, N., Thom, D., Thomas, E., Thompson, K., Thornton, P. E., Thuiller, W., Tichy, L., Tissue, D., Tjoelker, M. G., Tng, D. Y. P., Tobias, J., Torok, P., Tarin, T., Torres Ruiz, J. M., Tothmeresz, B., Treurnicht, M., Trivellone, V., Trolliet, F., Trotsiuk, V., Tsakalos, J. L., Tsiripidis, I., Tysklind, N., Umehara, T., Usoltsev, V., Vadeboncoeur, M., Vaezi, J., Valladares, F., Vamosi, J., van Bodegom, P. M., van Breugel, M., Van Cleemput, E., van de Weg, M., van der Merwe, S., van der Plas, F., van der Sande, M. T., van Kleunen, M., Van Meerbeek, K., Vanderwel, M., Vanselow, K. A., Varhammar, A., Varone, L., Vasquez Valderrama, M. Y., Vassilev, K., Vellend, M., Veneklaas, E. J., Verbeeck, H., Verheyen, K., Vibrans, A., Vieira, I., Villacis, J., Violle, C., Vivek, P., Wagner, K., Waldram, M., Waldron, A., Walker, A . P., Waller, M., Walther, G., Wang, H., Wang, F., Wang, W., Watkins, H., Watkins, J., Weber, U., Weedon, J. T., Wei, L., Weigelt, P., Weiher, E., Wells, A. W., Wellstein, C., Wenk, E., Westoby, M., Westwood, A., White, P. J., Whitten, M., Williams, M., Winkler, D. E., Winter, K., Womack, C., Wright, I. J., Wright, S. J., Wright, J., Pinho, B. X., Ximenes, F., Yamada, T., Yamaji, K., Yanai, R., Yankov, N., Yguel, B., Zanini, K. J., Zanne, A. E., Zeleny, D., Zhao, Y. P., Zheng, J., Zieminska, K., Zirbel, C. R., Zizka, G., Zo Bi, I. C., Zotz, G., Wirth, C., Systèmes d'élevage méditerranéens et tropicaux (UMR SELMET), Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-Institut National de la Recherche Agronomique (INRA)-Centre international d'études supérieures en sciences agronomiques (Montpellier SupAgro)-Institut national d’études supérieures agronomiques de Montpellier (Montpellier SupAgro), Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro), Laboratoire de Physique et Physiologie Intégratives de l’Arbre en environnement Fluctuant - Clermont Auvergne (PIAF), Université Clermont Auvergne (UCA)-Institut National de la Recherche Agronomique (INRA), Botanique et Modélisation de l'Architecture des Plantes et des Végétations (UMR AMAP), Institut de Recherche pour le Développement (IRD [France-Sud])-Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-Institut National de la Recherche Agronomique (INRA)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), Biodiversité, Gènes & Communautés (BioGeCo), Institut National de la Recherche Agronomique (INRA)-Université de Bordeaux (UB), SILVA (SILVA), AgroParisTech-Université de Lorraine (UL)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Ecologie des forêts de Guyane (UMR ECOFOG), Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-Institut National de la Recherche Agronomique (INRA)-AgroParisTech-Université de Guyane (UG)-Centre National de la Recherche Scientifique (CNRS)-Université des Antilles (UA), Unité Mixte de Recherche sur l'Ecosystème Prairial - UMR (UREP), Institut National de la Recherche Agronomique (INRA)-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS), Ecologie fonctionnelle et biogéochimie des sols et des agro-écosystèmes (UMR Eco&Sols), Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-Institut de Recherche pour le Développement (IRD)-Institut National de la Recherche Agronomique (INRA)-Centre international d'études supérieures en sciences agronomiques (Montpellier SupAgro)-Institut national d’études supérieures agronomiques de Montpellier (Montpellier SupAgro), Unité Expérimentale Forêt Pierroton (UEFP), Institut National de la Recherche Agronomique (INRA), Max Planck Institute for Biogeochemistry Max Planck SocietyFoundation CELLEX German Centre for Integrative Biodiversity Research (iDiv) Halle-Jena-Leipzig International Programme of Biodiversity Science (DIVERSITAS) International Geosphere-Biosphere Programme (IGBP) French Foundation for Biodiversity Research (FRB) GIS 'Climat, Environnement et Societe' France AXA Research Fund NERC Natural Environment Research Council Future Earth, Max Planck Institute for Biogeochemistry (MPI-BGC), Max-Planck-Gesellschaft, German Centre for Integrative Biodiversity Research (iDiv), Instituto Multidisciplinario de Biología Vegetal [Córdoba] (IMBIV), Consejo Nacional de Investigaciones Científicas y Técnicas [Buenos Aires] (CONICET)-Facultad de Ciencias Exactas, Físicas y Naturales [Córdoba], Universidad Nacional de Córdoba [Argentina]-Universidad Nacional de Córdoba [Argentina], Laboratoire d'Ecologie Alpine (LECA ), Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA), Imperial College London, Ecologie Systématique et Evolution (ESE), AgroParisTech-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Department of Zoology [Oxford], University of Oxford, Balliol College, Helsingin yliopisto = Helsingfors universitet = University of Helsinki, Tarbiat Modares University [Tehran], Università degli Studi Roma Tre = Roma Tre University (ROMA TRE), Department of Environment [Aegean], University of the Aegean, Institute of Ecology and Evolution [Bern, Switzerland], University of Bern, University of Tartu, Tohoku University [Sendai], Institut méditerranéen de biodiversité et d'écologie marine et continentale (IMBE), Avignon Université (AU)-Aix Marseille Université (AMU)-Institut de recherche pour le développement [IRD] : UMR237-Centre National de la Recherche Scientifique (CNRS), Universidad de Jaén (UJA), Instituto Alexander Von Humboldt, Bogota, Colombia, National Institute of Amazonian Research (INPA), Manaus, Brazil, Botany Department, Faculty of Science, Suez Canal University, Ismailia, Egypt, Laboratoire Agronomie et Environnement - Antenne Colmar (LAE-Colmar ), Laboratoire Agronomie et Environnement (LAE), Université de Lorraine (UL)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Université de Lorraine (UL)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Forest Sciences, University of Göttingen, Göttingen, Germany, Centre for Biodiversity and Sustainable Land-use [University of Göttingen] (CBL), Georg-August-University = Georg-August-Universität Göttingen, Instituto de Investigaciones en Recursos Naturales, Agroecología y Desarrollo Rural (IRNAD), Universidad Nacional de Río Negro, El Bolsón, Argentina, Consejo Nacional de Investigaciones Científicas y Técnicas [Buenos Aires] (CONICET), School of Environmental Sciences, University of Guelph, Pacific Northwest National Laboratory, Richland, WA, USA, University of Massachusetts [Amherst] (UMass Amherst), University of Massachusetts System (UMASS), Centre for Crop Systems Analysis, Wageningen University and Research [Wageningen] (WUR), University of Victoria [Canada] (UVIC), College of Science & Engineering, James Cook University, Smithfield, Qld, Australia, University of Pittsburgh, Pittsburgh, PA, USA, Centre for Forest Research, Institute for Integrative Systems Biology, Université Laval, Quebec, QC, Canada, Arizona State University, Tempe, AZ, USA, University of North Florida [Jacksonville] (UNF), Australian National University (ANU), Great Lakes Forestry Centre, Canadian Forest Service, Natural Resources Canada, Sault Ste. Marie, ON, Canada, Department of Biology [Copenhagen], Faculty of Science [Copenhagen], University of Copenhagen = Københavns Universitet (UCPH)-University of Copenhagen = Københavns Universitet (UCPH), Department of Ecology [Innsbruck], Leopold Franzens Universität Innsbruck - University of Innsbruck, University of Leeds, Royal Botanic Gardens Kew, Richmond, UK, Conservation Ecology, Groningen Institute for Evolutionary Life Sciences (GELIFES), University of Groningen, Groningen, The Netherlands, Lawrence Berkeley National Laboratory [Berkeley] (LBNL), Biology Department, Wilfrid Laurier University, Waterloo, ON, Canada, Department of Forest Resources, University of Minnesota, St. Paul, MN, USA, AgroParisTech, Lancaster Environment Centre, Lancaster University, University of Exeter, University of Adelaide, Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Institut Agro - Montpellier SupAgro, Département Environnements et Sociétés (Cirad-ES), Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad), University of California [Berkeley] (UC Berkeley), University of California (UC), Department of Horticulture and Landscape Architecture, Colorado State University, Fort Collins, CO, USA, Universiteit Gent = Ghent University (UGENT), Università degli Studi di Cagliari = University of Cagliari (UniCa), Helmholtz Zentrum für Umweltforschung = Helmholtz Centre for Environmental Research (UFZ), Royal Museum for Central Africa, Tervuren, Belgium, Bayreuth Center of Ecology and Environmental Research (BayCEER), Groningen Institute of Archaeology (GIA), University of Groningen, Groningen, The Netherlands, Department of Biological Sciences, University of Tennessee, Knoxville, TN, USA, Rocky Mountain Biological Laboratory, Crested Butte, CO, USA, Département des Science, Université du Québec À Montréal, Montreal, QC, Canada, Department of Biogeography, University of Bayreuth, Bayreuth, Germany, Museo Nacional de Ciencias Naturales [Madrid] (MNCN), Consejo Superior de Investigaciones Científicas [Madrid] (CSIC), Université Laval, Quebec, QC, Canada, Instituto de Ciencias Naturales, Universidad Nacional de Colombia, Bogota, Colombia, Fundación Natura, Bogota, Colombia, Environmental Change Institute, Laboratório de Estudos em Vegetação Campestre (LEVCamp), Programa de Pós-Graduação em Botânica, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil, Freie Universität Berlin, Berlin-Brandenburg Institute of Advanced Biodiversity Research (BBIB), Berlin, Germany, Laboratório de Ecologia Funcional de Comunidades (LABEF), Departamento de Botânica, Universidade Federal do Paraná, Curitiba, Brazil, School of Informatics, Computing, and Cyber Systems (SICCS), Northern Arizona University [Flagstaff], Institute of Ecology and Evolution, Friedrich Schiller University Jena, Jena, Germany, ETH Zurich, Universitatstrasse 16, 8092 Zurich, Switzerland, University of Gothenburg (GU), Laboratoire de Physique et Physiologie Intégratives de l’Arbre en environnement Fluctuant (PIAF), Université Clermont Auvergne [2017-2020] (UCA [2017-2020])-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Universidade Federal do Rio Grande do Sul [Porto Alegre] (UFRGS), School of Life Sciences, Arizona State University, Tempe, AZ, USA, USDA-ARS Rangeland Resources & Systems Research Unit, Fort Collins, CO, USA, Grupo de Investigación en Biodiversidad y Dinámica de Ecosistémas Tropicales - Universidad del Tolima, Ibagué, Colombia, Laboratory of Applied Physical Chemistry - ISOFYS (Gent, Belgium), School of Forest Resources and Conservation [Gainesville] (UF|IFAS|FFGS), Institute of Food and Agricultural Sciences [Gainesville] (UF|IFAS), University of Florida [Gainesville] (UF)-University of Florida [Gainesville] (UF), Senckenberg Biodiversity and Climate Research Centre, Frankfurt am Main, Germany, Department of Biological Sciences, Goethe Universität Frankfurt, Frankfurt am Main, Germany, Department of Biological Sciences, University of Cape Town, Cape Town, South Africa, SAEON Fynbos Node, Claremont, South Africa, Pacific Northwest National Laboratory, College Park, MD, USA, University of Leicester, Department of Environmental Science, Institute for Water and Wetland Research, Radboud University, Nijmegen, The Netherlands, Laboratório de Ecologia Vegetal (LEVEG), Programa de Pós-Graduação em Ecologia, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil, Archbold Biological Station’s Buck Island Ranch, FL, Lake Placid, USA, Department of Ecology and Evolutionary Biology, University of Connecticut, Storrs, CT, USA, University of Tasmania [Hobart, Australia] (UTAS), Facultad de Ciencias Forestales, Universidad Nacional de Santiago del Estero, Santiago del Estero, Argentina, Universität Hohenheim, School of Geography, University of Nottingham, Nottingham, UK, Department of Geography and Geology, Kingston University, Kingston upon Thames, UK, Martin-Luther-Universität Halle Wittenberg (MLU), Facultad de Ingeniería y Ciencias Hídricas, Universidad Nacional del Litoral (FICH-UNL), Santa Fe, Argentina, Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD [France-Sud])-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Institut de Recherche pour le Développement (IRD [Nouvelle-Calédonie]), University of Toronto at Scarborough, Friedrich-Schiller-Universität = Friedrich Schiller University Jena [Jena, Germany], Section for Ecoinformatics and Biodiversity, Department of Bioscience, Aarhus University, Aarhus, Denmark, Center for Biodiversity Dynamics in a Changing World (BIOCHANGE), Department of Bioscience, Aarhus University, Aarhus, Denmark, New Jersey Institute of Technology [Newark] (NJIT), University of Rostock, Università degli Studi di Roma 'La Sapienza' = Sapienza University [Rome] (UNIROMA), School of Biological Sciences, University of Aberdeen, Aberdeen, UK, Center for Ecosystem Science and Society, Northern Arizona University, Flagstaff, AZ, USA, School of Civil and Environmental Engineering, Yonsei University, Seoul, Korea, Departamento de Botânica, SCB, UFPR – Federal University of Parana, Curitiba, Brazil, Centro Politécnico, Universidade Federal do Paraná, Curitiba, Brazil, Università degli Studi di Milano = University of Milan (UNIMI), Risques, Ecosystèmes, Vulnérabilité, Environnement, Résilience (RECOVER), Aix Marseille Université (AMU)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Department of Environmental Systems Science, ETH Zürich, Zürich, Switzerland, Swiss Federal Institute for Forest, Snow and Landscape Research WSL, Centre of Excellence for Bioscurity Risk Analysis, The University of Melbourne, Melbourne, Vic., Australia, Centro de Investigaciones Biológicas (CSIC), Colgate University, Hamilton, NY, USA, School of Biosciences and Veterinary Medicine, Plant Diversity and Ecosystems Management Unit, University of Camerino, Camerino, Italy, University of the Basque Country/Euskal Herriko Unibertsitatea (UPV/EHU), Departamento de Geociencias y Medio Ambiente, Universidad Nacional de Colombia, Medellin, Colombia, Università degli studi di Parma = University of Parma (UNIPR), Centro Agronómico Tropical de Investigación y Enseñanza - Tropical Agricultural Research and Higher Education Center (CATIE), Université de Bordeaux (UB)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Department of Geography, King’s College London, London, UK, University of Minnesota [Twin Cities] (UMN), University of Minnesota System, Universitá degli Studi dell’Insubria = University of Insubria [Varese] (Uninsubria), Alma Mater Studiorum Università di Bologna [Bologna] (UNIBO), Universidad de Costa Rica (UCR), University of Arizona, Institute of Arctic Biology, University of Alaska [Fairbanks] (UAF), Royal Botanic Gardens [Kew], Department of Biology [Fort Collins], Colorado State University [Fort Collins] (CSU), WSL Swiss Federal Research Institute, Birmensdorf, Switzerland, Faculty of Forestry, University of British Columbia, Vancouver, BC, Canada, CREA – Research Centre for Forestry and Wood, Arezzo, Italy, Western Sydney University, ungwon University, Goesan, Chungbuk, Korea, Department of Botany and Zoology [Brno] (SCI / MUNI), Faculty of Science [Brno] (SCI / MUNI), Masaryk University [Brno] (MUNI)-Masaryk University [Brno] (MUNI), University of Pisa - Università di Pisa, Department of Agriculture and Forest Engineering (EAGROF), University of Lleida, Lleida, Spain, Joint Research Unit CTFC – AGROTECNIO, Solsona, Spain, University of California Riverside, Riverside, CA, USA, Faculty of Environmental Sciences, University of Life Sciences Prague, Institute of Botany of the Czech Academy of Sciences (IB / CAS), Czech Academy of Sciences [Prague] (CAS), University of Cambridge [UK] (CAM), Systems Ecology, Department of Ecological Science, Vrije Universiteit, Amsterdam, The Netherlands, School of Biological, Earth and Environmental Sciences, UNSW Sydney, Sydney, NSW, Australia, Faculté de foresterie, de géographie et de géomatique, Université Laval, Quebec, QC, Canada, Jonah Ventures, Boulder, CO, USA, Centro de Modelación y Monitoreo de Ecosistemas, Universidad Mayor, Santiago, Chile, Department of Wildlife, Fish and Environmental Studies, Swedish University of Agricultural Sciences (SLU), Centre for African Conservation Ecology, Department of Zoology, Nelson Mandela University, Port Elizabeth, South Africa, MTA Centre for Ecological Research [Tihany], Hungarian Academy of Sciences (MTA), University of Ljubljana, Santa Catarina State University, Lages, SC, Brazil, Department of Geography, Environment, and Spatial Sciences, Michigan State University, East Lansing, MI, USA, Eurac Research, Institute for Alpine Environment, Bozen-Bolzano, Italy, Institute of Biology of Komi Science Centre of the Ural Branch of the Russian Academy of Sciences, Syktyvkar, Komi Republic, Russia, University of Science – Vietnam National University Ho Chi Minh City, Ho Chi Minh City, Vietnam, Graduate School of Agriculture, Kyoto University, Kyoto, Japan, Graduate School of Global Environmental Studies, Kyoto University, Kyoto, Japan, Swedish Species Information Centre, University of Pretoria [South Africa], Helmholtz Centre for Environmental Research – UFZ, Leipzig, Germany, Department of Terrestrial Ecology, Netherlands Institute of Ecology, Wageningen, The Netherlands, Department Computational Landscape Ecology [UFZ Leipsig], Department Computational Hydrosystems, UFZ – Helmholtz Centre for Environmental Research, Leipzig, Germany, Seoul National University [Seoul] (SNU), Institute of Temperate Forest Sciences (ISFORT), Ripon, QC, Canada, UQO, Department of Natural Sciences, Ripon, QC, Canada, Université Paris-Sud - Paris 11 (UP11)-AgroParisTech-Centre National de la Recherche Scientifique (CNRS), Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-AgroParisTech-Université de Guyane (UG)-Centre National de la Recherche Scientifique (CNRS)-Université des Antilles (UA)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Goethe-Universität Frankfurt am Main, University of Florida [Gainesville] (UF), The University of Western Australia (UWA), School of Biological Sciences, The University of Western Australia, Department of Biological Sciences, Macquarie University, Department of Botany and Molecular Evolution, Senckenberg Research Institute and Natural History Museum, Universität Wien, Karlstad University [Sweden], Ferdowsi University of Mashhad (FUM), Flathead Lake Biological Station, University of Montana, School of Sustainability, Arizona State University, Programa Nacional de Pós-Doutorado (PNPD), Programa de Pós Graduação em Ecologia, Institute of Biology, University of Campinas UNICAMP, Institute for Ecosystem Research/Geobotany, Kiel University, School of Geography, Earth and Environmental Sciences [Birmingham], University of Birmingham [Birmingham], Justus-Liebig-Universität Gießen = Justus Liebig University (JLU), Global Ecology Unit CREAF-CEAB-CSIC, Universitat Autònoma de Barcelona (UAB), FFCLRP-USP, Department of Biology [USA], University of Maryland [College Park], University of Maryland System-University of Maryland System, University of A Coruña (UDC), School of Physics [UNSW Sydney] (UNSW), University of New South Wales [Sydney] (UNSW), Icahn School of Medicine at Mount Sinai [New York] (MSSM), University of Peking, Peking University [Beijing], Università degli Studi di Sassari = University of Sassari [Sassari] (UNISS), Ordu University - Ordu Üniversitesi, Lanzhou University, Universidad del Tolima, Research Centre for Forestry and Wood, Consiglio per la Ricerca in Agricoltura e l’analisi dell’economia agraria = Council for Agricultural Research and Economics (CREA), Brazilian Agricultural Research Corporation (Embrapa), Universidade de São Paulo = University of São Paulo (USP), Centro Agronomico Tropical de Investigacion y Ensenanza (CATIE), Queensland University of Technology [Brisbane] (QUT), University of Sussex, Harvard University, Institute for Alpine Environment, European Academy of Bozen-Bolzano (EURAC), Étude et compréhension de la biodiversité (ECODIV), Université de Rouen Normandie (UNIROUEN), Normandie Université (NU)-Normandie Université (NU), Laboratoire de Physique Atmosphérique et Planétaire (LPAP), Université de Liège, Université de Sherbrooke (UdeS), Station d'écologie théorique et expérimentale (SETE), Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Observatoire Midi-Pyrénées (OMP), Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS)-Météo-France -Institut de Recherche pour le Développement (IRD)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS)-Météo-France -Centre National de la Recherche Scientifique (CNRS), Centre d’Ecologie Fonctionnelle et Evolutive (CEFE), Université Paul-Valéry - Montpellier 3 (UPVM)-École Pratique des Hautes Études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD [France-Sud])-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Institut Agro - Montpellier SupAgro, University of Manchester [Manchester], Universidade Estadual de Campinas = University of Campinas (UNICAMP), Macquarie University, Universidade Federal do Rio Grande do Norte [Natal] (UFRN), Universidad Rey Juan Carlos [Madrid] (URJC), Universidad Nacional de la Patagonia Austral (UNPA), Universidade Regional de Blumenau (FURB), INIA-CIFOR, Southern Illinois University [Carbondale] (SIU), Center for Biodiversity Management, Instituto Federal de Educação Ciência e Tecnologia do Cearà, The Morton Arboretum, United States Department of Agriculture (USDA), Swiss Federal Institute of Technology, Aarhus University [Aarhus], Smithsonian Conservation Biology Institute, Centre Supérieur de la Recherche Scientifique (CSIC), Centre Supérieur de la Recherche Scientifique, Universidad del Rosario [Bogota], Norwegian University of Science and Technology [Trondheim] (NTNU), Norwegian University of Science and Technology (NTNU), Université Paris Sud (Paris 11), Senckenberg Research Institutes and Natural History Museums, Universidad de Chile = University of Chile [Santiago] (UCHILE), Joint Global Change Research Institute, Pacific Northwest National Laboratory (PNNL)-University of Maryland [College Park], Smithsonian Tropical Research Institute, University of Liege, Université de Liège - Gembloux, Institut Pasteur de Shanghai, Académie des Sciences de Chine - Chinese Academy of Sciences (IPS-CAS), Réseau International des Instituts Pasteur (RIIP), University of Bristol [Bristol], University of the Witwatersrand [Johannesburg] (WITS), Norwegian University of Life Sciences (NMBU), Murdoch University, Carnegie Museum of Natural History [Pittsburgh], Transilvania University of Brasov, Martin-Luther-University Halle-Wittenberg, Senckenberg Biodiversity and Climate Research Centre (SBiK-F), Goethe-Universität Frankfurt am Main-Senckenberg – Leibniz Institution for Biodiversity and Earth System Research - Senckenberg Gesellschaft für Naturforschung, Leibniz Association-Leibniz Association, Universität für Bodenkultur Wien = University of Natural Resources and Life [Vienne, Autriche] (BOKU), Santa Catarina State University (UDESC), University Centre Myerscough, Kiel University, Florida International University [Miami] (FIU), Division of Plant Ststematic and Ecology, Biology department, Université Catholique de Louvain = Catholic University of Louvain (UCL), University of Applied Sciences of Weihenstephan, Four Peaks Environmental Science and Data Solutions, Norsk institutt for bioøkonomi=Norwegian Institute of Bioeconomy Research (NIBIO), Kochi University of Technology (KUT), University of Illinois [Chicago] (UIC), University of Illinois System, Universitat de Barcelona (UB), Kyoto University, Tyumen State University, Oak Ridge National Laboratory [Oak Ridge] (ORNL), UT-Battelle, LLC, Universitat Politècnica de Catalunya [Barcelona] (UPC), Stanford University, University of Edinburgh, Polish Academy of Sciences (PAN), Philips Research Europe - Hamburg, Sector Medical Imaging Systems, Philips Research, Institute for Systematic Botany and Ecology, Universität Ulm - Ulm University [Ulm, Allemagne], Ecosystèmes, biodiversité, évolution [Rennes] (ECOBIO), Université de Rennes (UR)-Institut Ecologie et Environnement (INEE), Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS)-Observatoire des Sciences de l'Univers de Rennes (OSUR), Université de Rennes (UR)-Institut national des sciences de l'Univers (INSU - CNRS)-Université de Rennes 2 (UR2)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Institut national des sciences de l'Univers (INSU - CNRS)-Université de Rennes 2 (UR2)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Centre National de la Recherche Scientifique (CNRS), Universität Bayreuth, University of Copenhagen = Københavns Universitet (UCPH), Guangxi Normal University, University College of London [London] (UCL), Hobart - Tasmania 7001, University of Venda [South Africa] (UNIVEN), University of Melbourne, Philipps Universität Marburg = Philipps University of Marburg, Agrosystèmes Cultivés et Herbagers (ARCHE), Institut National de la Recherche Agronomique (INRA)-École nationale supérieure agronomique de Toulouse (ENSAT), Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Université de Toulouse (UT), Natural Resource Operations and Rural Development, Humboldt State University (HSU), Charles University [Prague] (CU), Karlsruhe Institute of Technology (KIT), Samara National Research University, Institute of Plant Sciences, Forestry and Forest Products Research Institute (FFPRI), Kenyon College, University of Garmian, State University of New York (SUNY), Institute for Biodiversity and Ecosystem Dynamics (IBED), University of Amsterdam [Amsterdam] (UvA), Universidad Nacional del Comahue [Neuquén] (UNCOMA), IT University of Copenhagen (ITU), Agricultural Research Organization, Landscape Ecology Group, University of Oldenburg, Western Carolina University, Xi'an Jiaotong-Liverpool University [Suzhou], Hokkaido University [Sapporo, Japan], Yokohama National University, Technische Universität Munchen - Université Technique de Munich [Munich, Allemagne] (TUM), Institut d Estudis Andorrans, Smithsonian Environmental Research Center (SERC), Humboldt University Of Berlin, University of California [Los Angeles] (UCLA), Department of Biodiversity, Macroecology and Biogeography, Yamagata University, Jomo Kenyatta University of Agriculture and Technology (JKUAT), Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-Institut de Recherche pour le Développement (IRD)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Institut Agro - Montpellier SupAgro, Université du Québec en Abitibi-Témiscamingue (UQAT), University of Saskatchewan [Saskatoon] (U of S), University of Natural Resources and Life Sciences, Institute of Mountain Risk Engineering - Vienna, Austria, University of Wyoming (UW), Département Performances des systèmes de production et de transformation tropicaux (Cirad-PERSYST), Nelson Mandela University [Port Elizabeth], University of Wisconsin - Eau Claire, Naturalis Biodiversity Center [Leiden], Département de biologie [Sherbrooke] (UdeS), Faculté des sciences [Sherbrooke] (UdeS), Université de Sherbrooke (UdeS)-Université de Sherbrooke (UdeS), Yangzhou University, Leipzig University, University Pablo de Olavide, Shanghai Jiao Tong University [Shanghai], Royal Botanical Gardens, Masaryk University [Brno] (MUNI), Department of Physiology, University of Debrecen Egyetem [Debrecen]-Research Centre for Molecular Medicine-Medical and Health Science Centre, Global Change Research Centre (CzechGlobe), Université du Québec à Trois-Rivières (UQTR), Natural Resources Institute Finland (LUKE), Universidade Federal de Alagoas = Federal University of Alagoas (UFAL), Lakehead University, Stockholm University, Universidad Nacional del Litoral [Santa Fe] (UNL), Universidade Federal do Paraná (UFPR), Bangor University, Universidad Autonoma del Estado de Morelos (UAEM), Manaaki Whenua – Landcare Research [Lincoln], Gorongosa National Park, Université de Montréal (UdeM), Tel Aviv University (TAU), University of Queensland [Brisbane], University of Wisconsin-Madison, University of Maine, Holden Arboretum, Hawkesbury Institute for he Environment, Laboratoire d'Ecologie Végétale et Biogéochimie, Université libre de Bruxelles (ULB), University of British Columbia (UBC), Research School of Biology, Universidade Federal de Pernambuco [Recife] (UFPE), School of Geosciences [Edinburgh], Ecology and Evolutionary Biology [Tucson] (EEB), University of Debrecen, Northern Forestry Centre, Canadian Forest Service - CFS (CANADA), University of Illinois at Urbana-Champaign [Urbana], Data61 [Canberra] (CSIRO), Australian National University (ANU)-Commonwealth Scientific and Industrial Research Organisation [Canberra] (CSIRO), University of Debrecen Egyetem [Debrecen], University of Vermont [Burlington], Fundação Zoobotânica do Rio Grande do Sul, University of Montana, Institut de RadioAstronomie Millimétrique (IRAM), Centre National de la Recherche Scientifique (CNRS), University of Freiburg [Freiburg], University of Hawaii, Institut Français de Pondichéry (IFP), Ministère de l'Europe et des Affaires étrangères (MEAE)-Centre National de la Recherche Scientifique (CNRS), Oklahoma State University [Stillwater] (OSU), Osaka City University, Charles Darwin Research Station (CDRS), Charles Darwin Foundation, Los Alamos National Laboratory (LANL), Zhejiang Normal University, European Academy of Bolzano, Universidad Distrital Francisco Jose de Caldas [Bogota], University of Bayreuth, Institute of Biology of Komi Scientific Centre of the Ural Branch of the Russian Academy of Sciences, Russian Academy of Sciences [Moscow] (RAS), CSIRO Land and Water, Commonwealth Scientific and Industrial Research Organisation [Canberra] (CSIRO), University of Canberra, CEH, Department of Systems and Science, Graduate School of Informatics, Kyoto University-Kyoto University, Departamento de Telemática, Faculdade de Engenharia Elétrica e de Computação (DT/FEEC), Universidad Nacional Autónoma de México = National Autonomous University of Mexico (UNAM), Moscow State University, Vrije Universiteit Amsterdam [Amsterdam] (VU), Meijo University, Institute of Ecology and Earth Sciences [Tartu], Astronomical Institute of the Czech Academy of Sciences (ASU / CAS), University of Nijmegen, University of New England (UNE), The James Hutton Institute, Democritus University of Thrace (DUTH), Institute of Ecology and Earth Sciences, University of Tartu, Spanish National Research Council (CSIC), Senckenberg Research Institute and Natural History Museum, University of Vienna [Vienna], Center for Desertification Research (CIDE), Universitat de València (UV), Universidad Autónoma de Madrid (UAM), Université de Jaén, National Institute for Research and Development in Forestry, Department of Plant Production (University of Milan), Tartu Observatory, Botanical Garden of the Samara University, Forschungszentrum Jülich GmbH, Tallinn University, Universität Regensburg (REGENSBURG), Universität Regensburg, School of Social Sciences [Cardiff], Cardiff University, Estonian University of Life Sciences (EMU), Sch Life Sci Weihenstephan, Arizona State University [Tempe] (ASU), Department of Forest Resources, University of Minnesota System-University of Minnesota System, Research Institute for Networks and Communications Engineering (RINCE), Dublin City University [Dublin] (DCU)-Science Foundation Ireland-Enterprise Ireland-Higher Education Authority-School of Electronic Engineering, Southwest University of Science and Technology [Mianyang] (SWUST), Universidade Federal do Acre (UFAC), Berlin-Brandenburg Institute of Advanced Biodiversity Research (BBIB), Centre méditérannéen de médecine moléculaire (C3M), Université Nice Sophia Antipolis (1965 - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Institut National de la Santé et de la Recherche Médicale (INSERM), Mississippi State University [Mississippi], University of Southampton, Yale University [New Haven], Brookhaven National Laboratory [Upton, NY] (BNL), UT-Battelle, LLC-Stony Brook University [SUNY] (SBU), State University of New York (SUNY)-State University of New York (SUNY)-U.S. Department of Energy [Washington] (DOE), East Stroudsburg University, INDEHESA, Forestry School, Universidad de Extremadura - University of Extremadura (UEX), Institute of Physical Geography [Frankfurt am Main], Universität Zürich [Zürich] = University of Zurich (UZH), Lake Ecosystems Group [Lancaster, U.K.] (Centre for Ecology & Hydrology), Lancaster Environment Centre [Lancaster, U.K.], University of Valladolid, Norwegian Institute for Nature Research (NINA), Universidad Nacional de Colombia [Bogotà] (UNAL), Instituto de Recursos Naturales y Agrobiología de Salamanca (IRNASA), Universidade de Coimbra [Coimbra], Algoma University, Senckenberg biodiversität und klima forschungszentrum (BIK-F), Forschungsinstitut Senckenberg (SGN), University of Nottingham, UK (UON), University of Würzburg = Universität Würzburg, Agence Française de Sécurité Sanitaire des Aliments (AFSSA), Herencia, Kirstenbosch Research Centre, South African National Biodiversity Institute, Federal University of Pernambuco [Recife], Sharplex Services, University of Hohenheim, Komarov Botanical Institute RAS, Center for Sustainability Science, Hokkaido, Département de Biologie, University of Regina (UR), Technische Universität Ilmenau (TU ), Universidade de Lisboa = University of Lisbon (ULISBOA), Universidade Federal de Lavras = Federal University of Lavras (UFLA), Università degli Studi di Padova = University of Padua (Unipd), Gothenburg Global Biodiversity Centre, Department of Biology [Gainesville] (UF|Biology), Texas Tech University [Lubbock] (TTU), Florida Museum of Natural History [Gainesville], KU Leuven, Embrapa Recursos Genéticos e Biotecnologia [Brasília], Universiteit Leiden, University of California [Riverside] (UC Riverside), Pacific Northwest National Laboratory (PNNL), University of Natural Resources and Applied Life Sciences, Vienna, (BOKU) and Competence Centre Wood K plus, University of Novi Sad, Instituto Nacional de Investigaciones en Biodiversidad y Medioambiente [Bariloche] (INIBIOMA-CONICET), Consejo Nacional de Investigaciones Científicas y Técnicas [Buenos Aires] (CONICET)-Universidad Nacional del Comahue [Neuquén] (UNCOMA), Slovak Academy of Sciences (SAS), Technical University in Zvolen (TUZVO), Faculty of Forestry and Wood Sciences, Czech University of Life Sciences Prague (CZU), University of Aberdeen, University of Maryland System, Universität Innsbruck [Innsbruck], Estacion Experimental de Zonas Aridas, Hacettepe University = Hacettepe Üniversitesi, Centre for Forest Research (CFR), Université du Québec à Montréal = University of Québec in Montréal (UQAM), Bioversity International [Montpellier], Bioversity International [Rome], Consultative Group on International Agricultural Research [CGIAR] (CGIAR)-Consultative Group on International Agricultural Research [CGIAR] (CGIAR), Department of Animal and Plant Sciences [Sheffield], University of Sheffield [Sheffield], The School for Field Studies, Quantum Optics and Laser Science, Blackett Laboratory, Blackett Laboratory, Imperial College London-Imperial College London, University of Delaware [Newark], Université Clermont Auvergne [2017-2020] (UCA [2017-2020]), Biodiversity and Ecosystem Services Research Group, Stellenbosch University, Czech University of Life Science, Aristotle University of Thessaloniki, Osaka Natural History Center, Ural State Forest Engineering University, University of New Hampshire (UNH), University of Calgary, Catholic University of Leuven - Katholieke Universiteit Leuven (KU Leuven), Hawkesbury Institute for the Environment [Richmond] (HIE), Computational & Applied Vegetation Ecology (CAVElab), Dept Forest & Water Management, Lab Forestry, Museu Paraense Emílio Goeldi, Federal University of Para - Universidade Federal do Pará - UFPA [Belém, Brazil] (UFPA), State Key Laboratory of Natural and Biomimetic Drugs, Fudan University [Shanghai], Department of Ecological Science [Amsterdam], Vrije Universiteit Brussel (VUB), Laboratoire de Biologie des Ligneux et des Grandes Cultures (LBLGC), Université d'Orléans (UO)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Department of Biology, Free University of Bozen-Bolzano, Dpt Biological Sciences, Macquarie University, Duke University [Durham], IFP Energies nouvelles (IFPEN), Department of Primary Industries, Graduate School of Integrated Arts and Sciences, Hiroshima University, Université de Tsukuba = University of Tsukuba, SUNY College of Environmental Science and Forestry (SUNY-ESF), Biological Sciences Department (BIOLOGICAL SCIENCES DEPARTMENT), Nanjing University (NJU), National Taiwan University [Taiwan] (NTU), Zhejiang University, Beijing Forestry University, Institut National Polytechnique Félix Houphouët-Boigny, Universität Leipzig, Max Planck Fellow Program for Christian Wirth, the International Programme of Biodiversity Science (DIVERSITAS), the International Geosphere‐Biosphere Programme (IGBP), Future Earth, the French Foundation for Biodiversity Research (FRB), and GIS ‘Climat, Environnement et Société’ France, JENS KATTGE, MAX PLANCK INSTITUTE FOR BIOGEOCHEMISTRY, GERMANY, ELLEN L. FRY, UNIVERSITY OF LIÈGE, BELGIUM, NIKOLAOS M. FYLLAS, UNIVERSITY OF THE AEGEAN, GREECE, GERHARD BÖNISCH, MAX PLANCK INSTITUTE FOR BIOGEOCHEMISTRY, GERMANY, SUSANNE TAUTENHAHN, MAX PLANCK INSTITUTE FOR BIOGEOCHEMISTRY, JENA, GERMANY, GIJSBERT D. A. WERNER, UNIVERSITY OF OXFORD, OXFORD, UK, TUOMAS AAKALA, UNIVERSITY OF HELSINKI, FINLAND, MEHDI ABEDI, TARBIAT MODARES UNIVERSITY, IRAN, ALICIA T. R. ACOSTA, UNIVERSITY OF ROMA TRE, ITALY, GEORGE C. ADAMIDIS, UNIVERSITY OF BERN, SWITZERLAND, KAIRI ADAMSON, UNIVERSITY OF TARTU, ESTONIA, MASAHIRO AIBA, TOHOKU UNIVERSITY, JAPAN., CÉCILE H. ALBERT, AIX MARSEILLE UNIV, UNIV AVIGNON, FRANCE., JULIO M. ALCÁNTARA, UNIVERSIDAD DE JAÉN, SPAIN, CAROLINA ALCÁZAR C, Instituto Alexander Von Humboldt, Colombia., HAMADA ALI, SUEZ CANAL UNIVERSITY, EGYPT, BERNARD AMIAUD, UNIVERSITÉ DE LORRAINE, FRANCE., CHRISTIAN AMMER, UNIVERSITY OF GÖTTINGEN, GERMANY, MARIANO M. AMOROSO, UNIVERSIDAD NACIONAL DE RÍO NEGRO, ARGENTINA, MADHUR ANAND, UNIVERSITY OF GUELPH, CANADA., MARIJN BAUTERS, GHENT UNIVERSITY, BELGIUM., ERIKA BAZZATO, UNIVERSITY OF CAGLIARI, ITALY., MICHAEL BECKMANN, Helmholtz Centre for Environmental Research, Germany., HANS BEECKMAN, ROYAL MUSEUM FOR CENTRAL AFRICA, BELGIUM., CARL BEIERKUHNLEIN, UNIVERSITY OF BAYREUTH, GERMANY., RENEE BEKKER, UNIVERSITY OF GRONINGEN, THE NETHERLANDS., JOANA BERGMANN, FREIE UNIVERSITÄT BERLIN, GERMANY., MARCOS BERGMANN CARLUCCI, UFPC, LOGAN BERNER, NORTHERN ARIZONA UNIVERSITY, USA., MARKUS BERNHARDT-RÖMERMANN, FRIEDRICH SCHILLER UNIVERSITY JENA, GERMANY., CHRISTOF BIGLER, ETH ZURICH, SWITZERLAND., FEDERICO BRUMNICH, UNIVERSIDAD NACIONAL DEL LITORAL (FICH-UNL), ARGENTINA, HANS HENRIK BRUUN, UNIVERSITY OF COPENHAGEN, DENMARK, DAVID BRUY, UNIVERSITÉ DE MONTPELLIER, FRANCE, SERRA W. BUCHANAN, UNIVERSITY OF TORONTO SCARBOROUGH, CANADA, ROBERT BUITENWERF, AARHUS UNIVERSITY, DENMARK, DANIEL E. BUNKER, NEW JERSEY INSTITUTE OF TECHNOLOGY, USA, JANA BÜRGER, UNIVERSITY OF ROSTOCK, GERMANY, SABINA BURRASCANO, SAPIENZA UNIVERSITY OF ROME, ITALY, DAVID F. R. P. BURSLEM, UNIVERSITY OF ABERDEEN, UK, BRADLEY J. BUTTERFIELD, NORTHERN ARIZONA UNIVERSITY, USA, CHAEHO BYUN, YONSEI UNIVERSITY, KOREA, MARINA C. SCALON, UFP, MARCO CACCIANIGA, UNIVERSITÀ DEGLI STUDI DI MILANO, ITALY, MARC CADOTTE, UNIVERSITY OF TORONTO SCARBOROUGH, CANADA, MAXIME CAILLERET, AIX?MARSEILLE UNIVERSITY, FRANCE, JAMES CAMAC, THE UNIVERSITY OF MELBOURNE, AUSTRALIA, JESÚS JULIO CAMARERO, INSTITUTO PIRENAICO DE ECOLOGÍA (IPE?CSIC), SPAIN, COURTNEY CAMPANY, COLGATE UNIVERSITY, USA, GIANDIEGO CAMPETELLA, UNIVERSITY OF CAMERINO, ITALY, JUAN ANTONIO CAMPOS, UNIVERSITY OF THE BASQUE COUNTRY UPV/EHU, SPAIN, LAURA CANO-ARBOLEDA, UNIVERSIDAD NACIONAL DE COLOMBIA, COLOMBIA, ROBERTO CANULLO, UNIVERSITY OF CAMERINO, ITALY, MICHELE CARBOGNANI, UNIVERSITY OF PARMA, ITALY, FABIO CARVALHO, LANCASTER UNIVERSITY, UK, BASTIEN CASTAGNEYROL, UNIV. BORDEAUX, FRANCE, JANE A. CATFORD, KING'S COLLEGE LONDON, UK, JEANNINE CAVENDER-BARES, UNIVERSITY OF MINNESOTA, USA, BRUNO E. L. CERABOLINI, UNIVERSITY OF INSUBRIA, ITALY, MARCO CERVELLINI, UNIVERSITY OF BOLOGNA, ITALY, EDUARDO CHACÓN-MADRIGAL, UNIVERSIDAD DE COSTA RICA, COSTA RICA, KENNETH CHAPIN, THE UNIVERSITY OF ARIZONA, USA, SAMANTHA DAWSON, SWEDISH UNIVERSITY OF AGRICULTURAL SCIENCES, AREND JACOBUS DE BEER, UNIVERSITY OF PRETORIA, SOUTH AFRICA, ANGEL DE FRUTOS, HELMHOLTZ CENTRE FOR ENVIRONMENTAL RESEARCH, GERMANY, LEANDRO DUARTE, UFRGS, EMILIE DUCOURET, UMR ECOFOG (AGROPARISTECH, CNRS, INRA, UNIVERSITÉ DES ANTILLES, UNIVERSITÉ DE LA GUYANE), FRANCE, STEFAN DULLINGER, UNIVERSITY OF VIENNA, AUSTRIA, DAN F. B. FLYNN, ARNOLD ARBORETUM OF HARVARD UNIVERSITY, USA, VERONIKA FONTANA, INSTITUTE FOR ALPINE ENVIRONMENT, ITALY, KYONG-SOOK CHUNG, JUNGWON UNIVERSITY, KOREA, MILAN CHYTRÝ, MASARYK UNIVERSITY, CZECH REPUBLIC, DANIELA CICCARELLI, UNIVERSITY OF PISA, ITALY, LLUÍS COLL, UNIVERSITY OF LLEIDA, SPAIN, COURTNEY G. COLLINS, UNIVERSITY OF CALIFORNIA RIVERSIDE, USA, LUISA CONTI, UNIVERSITY OF LIFE SCIENCES PRAGUE, CZECH REPUBLIC, DAVID COOMES, UNIVERSITY OF CAMBRIDGE, UK, JOHANNES H. C. CORNELISSEN, VRIJE UNIVERSITEIT, THE NETHERLANDS, WILLIAM K. CORNWELL, EARTH AND ENVIRONMENTAL SCIENCES, AUSTRALIA, PIERMARIA CORONA, CREA – RESEARCH CENTRE FOR FORESTRY AND WOOD, ITALY, MARIE COYEA, UNIVERSITÉ LAVAL, CANADA, JOSEPH CRAINE, JONAH VENTURES, USA, DYLAN CRAVEN, UNIVERSIDAD MAYOR, CHILE, JORIS P. G. M. CROMSIGT, SWEDISH UNIVERSITY OF AGRICULTURAL SCIENCES, SWEDEN, ANIKÓ CSECSERITS, MTA CENTRE FOR ECOLOGICAL RESEARCH, HUNGARY, KATARINA CUFAR, UNIVERSITY OF LJUBLJANA, SLOVENIA, MATTHIAS CUNTZ, UNIVERSITÉ DE LORRAINE, FRANCE, ANA CAROLINA DA SILVA, SANTA CATARINA STATE UNIVERSITY, BRAZIL, KYLA M. DAHLIN, MICHIGAN STATE UNIVERSITY, USA, MATTEO DAINESE, INSTITUTE FOR ALPINE ENVIRONMENT, ITALY, IGOR DALKE, INSTITUTE OF BIOLOGY OF KOMI SCIENCE CENTRE OF THE URAL BRANCH OF THE RUSSIAN ACADEMY OF SCIENCES, RUSSIA, MICHELE DALLE FRATTE, UNIVERSITY OF INSUBRIA, ITALY, ANH TUAN DANG-LE, UNIVERSITY HO CHI MINH CITY, VIETNAM, JIRÍ DANIHELKA, MASARYK UNIVERSITY, CZECH REPUBLIC, MASAKO DANNOURA, KYOTO UNIVERSITY, JAPAN, JONATHAN R. DE LONG, NETHERLANDS INSTITUTE OF ECOLOGY, THE NETHERLANDS, BENJAMIN DECHANT, SEOUL NATIONAL UNIVERSITY, REPUBLIC OF KOREA, SYLVAIN DELAGRANGE, INSTITUTE OF TEMPERATE FOREST SCIENCES (ISFORT), CANADA, NICOLAS DELPIERRE, UNIVERSITY OF PARIS?SUD, FRANCE, GÉRALDINE DERROIRE, UNIVERSITÉ DES ANTILLES, FRANCE, ARILDO S. DIAS, UNIVERSITÄT FRANKFURT, GERMANY, MILTON HUGO DIAZ-TORIBIO, UNIVERSITY OF FLORIDA, USA, PANAYIOTIS G. DIMITRAKOPOULOS, UNIVERSITY OF THE AEGEAN, GREECE, MARK DOBROWOLSKI, THE UNIVERSITY OF WESTERN AUSTRALIA, AUSTRALIA, DANIEL DOKTOR, HELMHOLTZ CENTRE FOR ENVIRONMENTAL RESEARCH – UFZ, GERMANY, PAVEL DREVOJAN, MASARYK UNIVERSITY, CZECH REPUBLIC, NING DONG, MACQUARIE UNIVERSITY, AUSTRALIA, JOHN DRANSFIELD, ROYAL BOTANIC GARDENS KEW, UK, STEFAN DRESSLER, DEPARTMENT OF BOTANY AND MOLECULAR EVOLUTION, GERMANY, WALTER DURKA, GERMAN CENTER FOR INTEGRATIVE BIODIVERSITY RESEARCH (IDIV) HALLE?JENA?LEIPZIG, GERMANY, REMKO DUURSMA, WESTERN SYDNEY UNIVERSITY, AUSTRALIA, OLGA DYMOVA, KOMI REPUBLIC, RUSSIA, E-VOJTKÓ, A., UNIVERSITY OF SOUTH BOHEMIA, CZECH REPUBLIC, ROLF LUTZ ECKSTEIN, KARLSTAD UNIVERSITY, SWEDEN, HAMID EJTEHADI, FERDOWSI UNIVERSITY OF MASHHAD, IRAN, JAMES ELSER, UNIVERSITY OF MONTANA, USA, THAISE EMILIO, UNIVERSITY OF CAMPINAS UNICAMP, BRAZIL, KRISTINE ENGEMANN, AARHUS UNIVERSITY, DENMARK, MOHAMMAD BAGHER ERFANIAN, FERDOWSI UNIVERSITY OF MASHHAD, IRAN, ALEXANDRA ERFMEIER, KIEL UNIVERSITY, KIEL, GERMANY, ADRIANE ESQUIVEL-MUELBERT, EARTH AND ENVIRONMENTAL SCIENCES, AUSTRALIA, GERD ESSER, JUSTUS LIEBIG UNIVERSITY, GERMANY, MARC ESTIARTE, SPANISH NATIONAL RESEARCH COUNCIL – CSIC, SPAIN, TOMAS F. DOMINGUES, DEPARTMENT OF BIOLOGY – FFCLRP/USP, BRAZIL, WILLIAM F. FAGAN, UNIVERSITY OF MARYLAND, USA, JAIME FAGÚNDEZ, UNIVERSITY OF A CORUÑA, SPAIN, DANIEL S. FALSTER, EVOLUTION & ECOLOGY RESEARCH CENTRE, AUSTRALIA, YING FAN, RUTGERS UNIVERSITY, USA, JINGYUN FANG, PEKING UNIVERSITY, CHINA, EMMANUELE FARRIS, UNIVERSITY OF SASSARI, ITALY, FATIH FAZLIOGLU, ORDU UNIVERSITY, TURKEY, YANHAO FENG, LANZHOU UNIVERSITY, CHINA, FERNANDO FERNANDEZ-MENDEZ, UNIVERSIDAD DEL TOLIMA, COLOMBIA, CARLOTTA FERRARA, CREA – RESEARCH CENTRE FOR FORESTRY AND WOOD, ITALY, JOICE NUNES FERREIRA, CPATU, ALESSANDRA FIDELIS, (UNESP), RIO CLARO, BRAZIL, BRYAN FINEGAN, CATIE-CENTRO AGRONÓMICO TROPICAL DE INVESTIGACIÓN Y ENSEÑANZA, COSTA RICA, JENNIFER FIRN, QUEENSLAND UNIVERSITY OF TECHNOLOGY (QUT), AUSTRALIA, TIMOTHY J. FLOWERS, UNIVERSITY OF SUSSEX, UK, ESTELLE FOREY, UNIVERSITÉ DE ROUEN, FRANCE, CRISTIANE FORGIARINI, UFRGS, BRAZIL., LOUIS FRANÇOIS, UNIVERSITY OF LIÈGE, BELGIUM., MARCELO FRANGIPANI, UFRGS, BRAZIL, DOROTHEA FRANK, MAX PLANCK INSTITUTE FOR BIOGEOCHEMISTRY, GERMANY, CEDRIC FRENETTE-DUSSAULT, GÉOPOLE DE L'UNIVERSITÉ DE SHERBROOKE, CANADA, GRÉGOIRE T. FRESCHET, PAUL SABATIER UNIVERSITY TOULOUSE, FRANCE, PAUL LEADLEY, UNIVERSITY OF PARIS-SUD, UNIVERSITÉ PARIS-SACLAY, ORSAY, FRANCE, IZABELA ALEIXO, NATIONAL INSTITUTE OF AMAZONIAN RESEARCH (INPA), BRAZIL, SANDRA DÍAZ, UNIVERSIDAD NACIONAL DE CÓRDOBA, ARGENTINA, SANDRA LAVOREL, UNIV. SAVOIE MONT BLANC, LECA, GRENOBLE, FRANCE, IAIN COLIN PRENTICE, IMPERIAL COLLEGE, UK., CAROLYN ANDERSON, UNIVERSITY OF MASSACHUSETTS AMHERST, USA, NIELS ANTEN, WAGENINGEN UNIVERSITY, THE NETHERLANDS, JOSEPH ANTOS, UNIVERSITY OF VICTORIA, CANADA, DEBORAH MATTOS GUIMARÃES APGAUA, JAMES COOK UNIVERSITY, AUSTRALIA, TIA-LYNN ASHMAN, UNIVERSITY OF PITTSBURGH, USA, DEGI HARJA ASMARA, UNIVERSITÉ LAVAL, CANADA, GREGORY P. ASNER, ARIZONA STATE UNIVERSITY, USA., MICHAEL ASPINWALL, UNIVERSITY OF NORTH FLORIDA, USA., OWEN ATKIN, AUSTRALIAN NATIONAL UNIVERSITY, AUSTRALIA., ISABELLE AUBIN, NATURAL RESOURCES CANADA, LARS BAASTRUP-SPOHR, UNIVERSITY OF COPENHAGEN, DENMARK., KHADIJEH BAHALKEH, TARBIAT MODARES UNIVERSITY, IRAN., MICHAEL BAHN, UNIVERSITY OF INNSBRUCK, AUSTRIA., TIMOTHY BAKER, UNIVERSITY OF LEEDS, LEEDS, UK., WILLIAM J. BAKER, ROYAL BOTANIC GARDENS KEW, UK., JAN P. BAKKER, UNIVERSITY OF GRONINGEN, THE NETHERLANDS., DENNIS BALDOCCHI, UNIVERSITY OF CALIFORNIA BERKELEY, USA., JENNIFER BALTZER, WILFRID LAURIER UNIVERSITY, CANADA, ARINDAM BANERJEE, UNIVERSITY OF MINNESOTA, USA., ANNE BARANGER, AGROPARISTECH, FRANCE., JOS BARLOW, LANCASTER UNIVERSITY, UK., DIEGO R. BARNECHE, UNIVERSITY OF EXETER, UK., ZDRAVKO BARUCH, THE UNIVERSITY OF ADELAIDE, AUSTRALIA., DENIS BASTIANELLI, UNIV MONTPELLIER, FRANCE., JOHN BATTLES, UNIVERSITY OF CALIFORNIA AT BERKELEY, USA, WILLIAM BAUERLE, COLORADO STATE UNIVERSITY, USA, SOLVEIG FRANZISKA BUCHER, FRIEDRICH?SCHILLER?UNIVERSITÄT JENA, GERMANY, GAVIN BELFRY, UNIVERSITY OF TENNESSEE, USA., MICHAEL BELLUAU, UNIVERSITÉ DU QUÉBEC À MONTRÉAL, CANADA., MIRELA BELOIU, UNIVERSITY OF BAYREUTH, GERMANY., RAQUEL BENAVIDES, MUSEO NACIONAL DE CIENCIAS NATURALES-CSIC, SPAIN., LAHCEN BENOMAR, UNIVERSITÉ LAVAL, CANADA., MARY LEE BERDUGO-LATTKE, UNIVERSIDAD NACIONAL DE COLOMBIA, COLOMBIA., ERIKA BERENGUER, UNIVERSITY OF OXFORD, UK., RODRIGO BERGAMIN, UFRS, NINA BUCHMANN, ETH ZURICH, ZURICH, SWITZERLAND, ANNE D. BJORKMAN, UNIVERSITY OF GOTHENBURG, SWEDEN., CHRIS BLACKMAN, UNIVERSITÉ CLERMONT-AUVERGNE, FRANCE., CAROLINA BLANCO, UFRGS, BENJAMIN BLONDER, ARIZONA STATE UNIVERSITY, USA., DANA BLUMENTHAL, USDA-ARS RANGELAND RESOURCES & SYSTEMS RESEARCH UNIT, USA., KELLY T. BOCANEGRA-GONZÁLEZ, UNIVERSIDAD DEL TOLIMA, COLOMBIA., PASCAL BOECKX, GHENT UNIVERSITY, BELGIUM., STEPHANIE BOHLMAN, UNIVERSITY OF FLORIDA, USA., KATRIN BÖHNING-GAESE, UNIVERSITÄT FRANKFURT, GERMANY., LAURA BOISVERT-MARSH, UNIVERSITÄT FRANKFURT, GERMANY., WILLIAM BOND, UNIVERSITY OF CAPE TOWN, SOUTH AFRICA., BEN BOND-LAMBERTY, COLLEGE PARK, USA., ARNOUD BOOM, UNIVERSITY OF LEICESTER, UK., COLINE C. F. BOONMAN, RADBOUD UNIVERSITY, THE NETHERLANDS., KAUANE BORDIN, UFRGS, ELIZABETH H. BOUGHTON, ARCHBOLD BIOLOGICAL STATION'S BUCK ISLAND RANCH, USA., VANESSA BOUKILI, UNIVERSITY OF CONNECTICUT, USA, DAVID M. J. S. BOWMAN, UNIVERSITY OF TASMANIA, AUSTRALIA., SANDRA BRAVO, UNIVERSIDAD NACIONAL DE SANTIAGO DEL ESTERO, MARCO RICHARD BRENDEL, UNIVERSITY OF HOHENHEIM, MARTIN R. BROADLEY, UNIVERSITY OF NOTTINGHAM, UK, KERRY A. BROWN, KINGSTON UNIVERSITY, UK., HELGE BRUELHEIDE, MARTIN LUTHER UNIVERSITY HALLE?WITTENBERG, GERMANY, FERNANDO CASANOVES, CATIE-CENTRO AGRONÓMICO TROPICAL DE INVESTIGACIÓN Y ENSEÑANZA, COSTA RICA, F. STUART CHAPIN, UNIVERSITY OF ALASKA FAIRBANKS, USA, STEFANO CHELLI, UNIVERSITY OF CAMERINO, ITALY, SI?CHONG CHEN, ROYAL BOTANIC GARDENS, UK, ANPING CHEN, COLORADO STATE UNIVERSITY, USA, PAOLO CHERUBINI, UNIVERSITY OF BRITISH COLUMBIA, CANADA, FRANCESCO CHIANUCCI, CREA – RESEARCH CENTRE FOR FORESTRY AND WOOD, ITALY, BRENDAN CHOAT, WESTERN SYDNEY UNIVERSITY, AUSTRALIA, GUILHERME G. MAZZOCHINI, UNIVERSITY OF CAMPINAS, CAMPINAS, BRAZIL, SOPHIE GACHET, UNIV AVIGNON, FRANCE, RACHAEL GALLAGHER, MACQUARIE UNIVERSITY, AUSTRALIA, GISLENE GANADE, UFRN, BRAZIL., MARY-CLAIRE GLASENHARDT, THE MORTON ARBORETUM, USA, ALAIN HAMBUCKERS, UNIVERSITY OF LIÈGE, BELGIUM, MASAE ISHIHARA, KYOTO UNIVERSITY, JAPAN, LEONID IVANOV, TYUMEN STATE UNIVERSITY, RUSSIA, LARISSA IVANOVA, TYUMEN STATE UNIVERSITY, RUSSIA., COLLEEN M. IVERSEN, OAK RIDGE NATIONAL LABORATORY, USA, JORDI IZQUIERDO, Universitat Politècnica de Catalunya, Spain, ROBERT B. JACKSON, STANFORD UNIVERSITY, USA, FRANCESCA GANGA, UNIVERSITY OF CAGLIARI, ITALY, PABLO GARCÍA-PALACIOS, UNIVERSIDAD REY JUAN CARLOS, SPAIN, VERÓNICA GARGAGLIONE, UNIVERSIDAD NACIONAL DE LA PATAGONIA AUSTRAL, ARGENTINA, ERIC GARNIER, UNIV. MONTPELLIER, FRANCE, JOSE LUIS GARRIDO, ESTACIÓN EXPERIMENTAL DEL ZAIDÍN, SPAIN, ANDRÉ LUÍS DE GASPER, UNIVERSIDADE REGIONAL DE BLUMENAU, BRAZIL, GUILLERMO GEAIZQUIERDO, INIA?CIFOR, SPAIN, DAVID GIBSON, SOUTHERN ILLINOIS UNIVERSITY CARBONDALE, USA, ANDREW N. GILLISON, CENTER FOR BIODIVERSITY MANAGEMENT, AUSTRALIA, AELTON GIROLDO, INSTITUTO FEDERAL DE EDUCAÇÃO CIÊNCIA E TECNOLOGIA DO CEARÁ, BRAZIL, SEAN GLEASON, WATER MANAGEMENT AND SYSTEMS RESEARCH UNIT, USA, MARIANA GLIESCH, INSTITUTE OF INTEGRATIVE BIOLOGY, SWITZERLAND, EMMA GOLDBERG, UNIVERSITY OF MINNESOTA, USA, BASTIAN GÖLDEL, AARHUS UNIVERSITY, DENMARK, ERIKA GONZALEZ-AKRE, NORWEGIAN UNIVERSITY OF SCIENCE AND TECHNOLOGY NTNU, NORWAY, JOSE L. GONZALEZ-ANDUJAR, CSIC-INSTITUTE FOR SUSTAINABLE AGRICULTURE (IAS), SPAIN, ANDRÉS GONZÁLEZ-MELO, UNIVERSIDAD DEL ROSARIO, COLOMBIA, ANA GONZÁLEZ-ROBLES, UNIVERSIDAD DE JAÉN, SPAIN, BENTE JESSEN GRAAE, NORWEGIAN UNIVERSITY OF SCIENCE AND TECHNOLOGY NTNU, NORWAY, ELENA GRANDA, UNIVERSITY OF ALCALÁ, SPAIN, SARAH GRAVES, UNIVERSITY OF FLORIDA, USA, WALTON A. GREEN, HARVARD UNIVERSITY, USA, THOMAS GREGOR, SENCKENBERG RESEARCH INSTITUTE AND NATURAL HISTORY MUSEUM, GERMANY, NICOLAS GROSS, UNIVERSIDAD REY JUAN CARLOS, SPAIN, GREG R. GUERIN, THE UNIVERSITY OF ADELAIDE, AUSTRALIA, ANGELA GÜNTHER, MAX PLANCK INSTITUTE FOR BIOGEOCHEMISTRY, GERMANY, ALVARO G. GUTIÉRREZ, UNIVERSIDAD DE CHILE, CHILE, LILLIE HADDOCK, COLLEGE PARK, USA, ANNA HAINES, THE UNIVERSITY OF MANCHESTER, UK, JEFFERSON HALL, SMITHSONIAN TROPICAL RESEARCH INSTITUTE, REPUBLIC OF PANAMA, WENXUAN HAN, CHINA AGRICULTURAL UNIVERSITY, CHINA, SANDY P. HARRISON, UNIVERSITY OF READING, UK, WESLEY HATTINGH, UNIVERSITY OF THE WITWATERSRAND, SOUTH AFRICA, JOSEPH E. HAWES, ANGLIA RUSKIN UNIVERSITY, UK, TIANHUA HE, CURTIN UNIVERSITY, AUSTRALIA, PENGCHENG HE, CHINESE ACADEMY OF SCIENCES, CHINA, JACOB MASON HEBERLING, CARNEGIE MUSEUM OF NATURAL HISTORY, USA, AVELIINA HELM, UNIVERSITY OF TARTU, ESTONIA, STEFAN HEMPEL, FREIE UNIVERSITÄT BERLIN, GERMANY, JÖRN HENTSCHEL, FRIEDRICH-SCHILLER-UNIVERSITÄT JENA, GERMANY, BRUNO HÉRAULT, UNIVERSITÉ DE MONTPELLIER, FRANCE, ANA-MARIA HERE, TRANSILVANIA UNIVERSITY OF BRASOV, ROMANIA, KATHARINA HERZ, MARTIN LUTHER UNIVERSITY HALLE?WITTENBERG, GERMANY, MYRIAM HEUERTZ, UNIV. BORDEAUX, FRANCE, THOMAS HICKLER, GOETHE UNIVERSITY, GERMANY, PETER HIETZ, UNIVERSITY OF NATURAL RESOURCES AND LIFE SCIENCES, AUSTRIA, PEDRO HIGUCHI, SANTA CATARINA STATE UNIVERSITY, BRAZIL, ANDREW L. HIPP, THE MORTON ARBORETUM, USA, ANDREW HIRONS, UNIVERSITY CENTRE MYERSCOUGH, UK, MARIA HOCK, INSTITUTE FOR ECOSYSTEM RESEARCH/GEOBOTANY, GERMANY, JAMES AARON HOGAN, FLORIDA INTERNATIONAL UNIVERSITY, USA, KAREN HOLL, UNIVERSITY OF CALIFORNIA, USA, OLIVIER HONNAY, PLANT CONSERVATION AND POPULATION BIOLOGY, BELGIUM, KNUT ANDERS HOVSTAD, DEPARTMENT OF LANDSCAPE AND BIODIVERSITY, NORWAY, TOMOAKI ICHIE, KOCHI UNIVERSITY, JAPAN, BORIS IGIC, UNIVERSITY OF ILLINOIS AT CHICAGO, USA, ESTELA ILLA, UNIVERSITAT DE BARCELONA, SPAIN, MARNEY ISAAC, UNIVERSITY OF TORONTO, CANADA, BENJAMIN JACKSON, UNIVERSITY OF EDINBURGH, SCOTLAND, HERVÉ JACTEL, UNIV. BORDEAUX, FRANCE, ANDRZEJ M. JAGODZINSKI, UNIVERSITY OF LIFE SCIENCES, POLAND, UTE JANDT, MARTIN LUTHER UNIVERSITY HALLE-WITTENBERG, GERMANY, STEVEN JANSEN, ULM UNIVERSITY, GERMANY, THOMAS, University of Oxford [Oxford], University of Helsinki, Tarbiat Modaras University, Roma Tre University, Institut National de la Recherche Agronomique (INRA)-Université de Lorraine (UL)-Institut National de la Recherche Agronomique (INRA)-Université de Lorraine (UL), Centre for Biodiversity and Sustainable Land-use, University of Göttingen, Göttingen, Germany, Department of Biology, University of North Florida, Jacksonville, FL, USA, University of Copenhagen = Københavns Universitet (KU)-University of Copenhagen = Københavns Universitet (KU), Department of Range Management, Faculty of Natural Resources and Marine Sciences, Tarbiat Modares University, Noor, Iran, University of Innsbruck, School of Geography, University of Leeds, Leeds, UK, Centre for Ecology and Conservation, College of Life and Environmental Sciences, University of Exeter, Penryn, UK., School of Biological Sciences, The University of Adelaide, Adelaide, SA, Australia, Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-Centre international d'études supérieures en sciences agronomiques (Montpellier SupAgro)-Institut national d’études supérieures agronomiques de Montpellier (Montpellier SupAgro), Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), University of California at Berkeley, Berkeley, CA, USA, Department of Green Chemistry and Technology, Ghent University, Gent, Belgium, Department of Environment, Ghent University, Gent, Belgium, Department of Life and Environmental Sciences, Botany Division, University of Cagliari, Cagliari, Italy, Museo Nacional de Ciencias Naturales-CSIC, Madrid, Spain, Environmental Change Institute, University of Oxford, Oxford, UK, Institut für Biologie, Freie Universität Berlin, Berlin, Germany, Department of Biological and Environmental Sciences, University of Gothenburg, Gothenburg, Sweden, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil, Universiteit Gent = Ghent University [Belgium] (UGENT), School of Geography, Geology and Environment, University of Leicester, Leicester, UK, Institute of Landscape and Plant Ecology, University of Hohenheim, Stuttgart, Germany, Institute of Biology/Geobotany and Botanical Garden, Martin Luther University Halle-Wittenberg, Halle, Germany, German Center for Integrative Biodiversity Research (iDiv) Halle-Jena- Leipzig, Leipzig, Germany, University of Toronto [Scarborough, Canada], Faculty of Agricultural and Environmental Sciences, University of Rostock, Rostock, Germany, Università degli Studi di Roma 'La Sapienza' = Sapienza University [Rome], Dipartimento di Bioscienze, Università degli Studi di Milano, Milano, Italy, Department of Plant Biology and Ecology, University of the Basque Country UPV/ EHU, Bilbao, Spain, Department of Chemistry, Life Sciences and Environmental Sustainability, University of Parma, Parma, Italy, Department of Biotechnology and Life Sciences, University of Insubria, Varese, Italy, BIGEA, Department of Biological, Geological and Environmental Sciences, Alma Mater Studiorum – University of Bologna, Bologna, Italy, Escuela de Biología, Universidad de Costa Rica, San José, Costa Rica, The University of Arizona, Tucson, AZ, USA, University of Alaska [Anchorage], Royal Botanic Gardens, Kew, Department of Biology, University of Pisa, Pisa, Italy, Department of Plant Sciences, University of Cambridge, Cambridge, UK, Biotechnical Faculty, University of Ljubljana, Ljubljana, Slovenia, Institut National de la Recherche Agronomique (INRA)-Université de Lorraine (UL)-AgroParisTech, Department of Plant and Soil Sciences, University of Pretoria, Pretoria, South Africa, Department of Landscape Architecture and Rural Systems Engineering, Seoul National University, Seoul, Republic of Korea, Department of Botany and Biodiversity Research, University of Vienna, Department of Environmental and Life Sciences – Biology, Karlstad University, Quantitative Plant Ecology and Biodiversity Research Laboratory, Department of Biology, Faculty of Science, Ferdowsi University of Mashhad, Justus Liebig University, Justus-Liebig-Universität Gießen (JLU), University of Sassari, Consiglio per la Ricerca in Agricoltura e l’analisi dell’economia agraria (CREA), Universidade de São Paulo (USP), Harvard University [Cambridge], Federal University of Rio Grande do Sul, Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Observatoire Midi-Pyrénées (OMP), Météo France-Centre National d'Études Spatiales [Toulouse] (CNES)-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD)-Météo France-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD), Université Paul-Valéry - Montpellier 3 (UPVM)-Centre international d'études supérieures en sciences agronomiques (Montpellier SupAgro)-École pratique des hautes études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD [France-Sud])-Institut national d’études supérieures agronomiques de Montpellier (Montpellier SupAgro), University of Campinas [Campinas] (UNICAMP), University of Cagliari, Universidad de Chile, University of Natural Resources and Life Sciences (BOKU), University of California, Norwegian Institute of Bioeconomy Research (NIBIO), Kyoto University [Kyoto], Centre National de la Recherche Scientifique (CNRS)-Observatoire des Sciences de l'Univers de Rennes (OSUR)-Institut Ecologie et Environnement (INEE), Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS)-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES), University of Copenhagen = Københavns Universitet (KU), University of Venda, Philipps University of Marburg, Institut National de la Recherche Agronomique (INRA)-École nationale supérieure agronomique de Toulouse [ENSAT]-Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées, State University of New York, Stonybrook, IT University of Copenhagen, Smithsonian Environmental Research Center, Humboldt University of Berlin, Georg-August-University [Göttingen], Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-Institut de Recherche pour le Développement (IRD)-Centre international d'études supérieures en sciences agronomiques (Montpellier SupAgro)-Institut national d’études supérieures agronomiques de Montpellier (Montpellier SupAgro), Nelson Mandela Metropolitan University [Port Elizabeth, South Africa], Netherlands Centre for Biodiversity Naturalis, University of Leipzig [Leipzig, Allemagne], Unité d'Agronomie, University of Debrecen-Research Centre for Molecular Medicine-Medical and Health Science Centre, Global Change Research Institute, University of California [Berkeley], Natural resources institute Finland, Universita degli Studi di Cagliari [Cagliari], Tel Aviv University [Tel Aviv], Oklahoma State University [Stillwater], Kyoto University [Kyoto]-Kyoto University [Kyoto], Universidade Estadual de Campinas (UNICAMP), Universidad Nacional Autónoma de México (UNAM), Vrije universiteit = Free university of Amsterdam [Amsterdam] (VU), Universidad Autonoma de Madrid (UAM), University of Parma = Università degli studi di Parma [Parme, Italie], University of Milan, Forschungszentrum Juelich, Université Nice Sophia Antipolis (... - 2019) (UNS), U.S. Department of Energy [Washington] (DOE)-UT-Battelle, LLC-Stony Brook University [SUNY] (SBU), State University of New York (SUNY)-State University of New York (SUNY), University of Extremadura, University of Göttingen - Georg-August-Universität Göttingen, Universidade de Lisboa (ULISBOA), Federal University of Lavras, Universita degli Studi di Padova, Leiden University, University of California [Riverside] (UCR), Ferdowsi University of Mashhad, Museo Nacional de Ciencias Naturales (MNCN), Departments of Botany and Zoology, Federal University of Para - Universidade Federal do Para [Belem - Brésil], Institut National de la Recherche Agronomique (INRA)-Université d'Orléans (UO), Institut national polytechnique Félix Houphouët-Boigny, Universität Leipzig [Leipzig], Institut National de la Recherche Agronomique (INRA)-Université Clermont Auvergne (UCA), Institut national d’études supérieures agronomiques de Montpellier (Montpellier SupAgro), Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Centre international d'études supérieures en sciences agronomiques (Montpellier SupAgro)-Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-Institut de Recherche pour le Développement (IRD)-Institut National de la Recherche Agronomique (INRA), Consejo Nacional de Investigaciones Científicas y Técnicas, Instituto Multidisciplinario de Biología Vegetal (IMBIV), and Factulad de Ciencias Exactas, Físicas y Naturales, Universidad Nacional de Córdoba, Córdoba, Argentina, Laboratoire d'Ecologie Alpine (LECA), Centre National de la Recherche Scientifique (CNRS)-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Université Joseph Fourier - Grenoble 1 (UJF)-Université Grenoble Alpes (UGA), Imperial College London, London SW7 2AZ, UK., Department of Zoology, University of Oxford, Oxford, UK, Balliol College, University of Oxford, Oxford, UK, University of Roma Tre, Rome, Italy, Biodiversity Conservation Laboratory, Department of Environment, University of the Aegean, Mytilene, Greece, Institute of Ecology and Evolution, University of Bern, Bern, Switzerland, Tartu Observatory, University of Tartu, Tartumaa, Estonia, Graduate School of Life Sciences, Tohoku University, Sendai, Japan, Centre National de la Recherche Scientifique (CNRS)-Institut de recherche pour le développement [IRD] : UMR237-Aix Marseille Université (AMU)-Avignon Université (AU), Universidad de Jaén, Jaén, Spain, UMR Nancy-Université- INRA Agronomie et Environnement Nancy-Colmar, Nancy Université, Conicet-Consejo Nacional de Investigaciones Científicas y Técnicas, Buenos Aires, Argentina, Environmental Sciences, Guelph, University of Massachusetts Amherst, Amherst, MA, USA, Wageningen University and Research Center (WUR), University of Victoria, Victoria, BC, Canada, Department of Ecology, University of Innsbruck, Innsbruck, Austria, Department of Biological Sciences-Lancaster University, Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-Centre international d'études supérieures en sciences agronomiques (Montpellier SupAgro)-Institut national d’études supérieures agronomiques de Montpellier (Montpellier SupAgro)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Helmholtz Centre for Environmental Research (UFZ), School of Informatics, Computing, and Cyber Systems, Northern Arizona University, Flagstaff, AZ, USA, Université Clermont Auvergne (UCA)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Universiteit Gent [Ghent], School of Forest Resources and Conservation, University of Florida, Gainesville, FL, USA, University of Tasmania, Hobart, Tas., Australia, AMAP, IRD, Herbier de Nouvelle-Calédonie, Nouméa, New Caledonia, Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS)-Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-Institut de Recherche pour le Développement (IRD [France-Sud])-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Friedrich-Schiller-Universität Jena, Jena, Germany, Università degli Studi di Roma 'La Sapienza' [Rome], wiss Federal Institute for Forest, Snow and Landscape Research WSL, Birmensdorf, Switzerland, Consejo Superior de Investigaciones Científicas [Spain] (CSIC), Tropical Agricultural Centre for Research and Higher Education (CATIE), Tropical Agricultural Centre for Research and Higher Education, Univ. Bordeaux, INRAE, BIOGECO, Cestas, France, Department of Ecology, Evolution, and Behavior, University of Minnesota, St. Paul, MN, USA, Royal Botanic Gardens, Kew, West Sussex, UK, Department of Biology, Colorado State University, Fort Collins, CO, USA, Hawkesbury Institute for the Environment, Western Sydney University, Sydney, NSW, Australia, Department of Botany and Zoology, Masaryk University, Brno, Czech Republic, Faculty of Environmental Sciences, University of Life Sciences Prague, Praha-Suchdol, Czech Republic, Institute of Botany, Czech Academy of Sciences, Třeboň, Czech Republic, Department of Wildlife, Fish and Environmental Studies, Swedish University of Agricultural Sciences, Umeå, Sweden, MTA Centre for Ecological Research, Tihany, Hungary, Swedish Species Information Centre, Swedish University of Agricultural Sciences, Uppsala, Sweden, Université des Antilles (UA)-Centre National de la Recherche Scientifique (CNRS)-Université de Guyane (UG)-AgroParisTech-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad), University of Florida [Gainesville], UFZ - Helmholtz Centre for Environmental Research, School of Geography, Earth and Environmental Sciences – University of Birmingham, Universitat Autònoma de Barcelona [Barcelona] (UAB), University of Ordu, Council for Agricultural Research and Economics (CREA), Université de Sherbrooke [Sherbrooke], Université Paul-Valéry - Montpellier 3 (UM3)-Institut National de la Recherche Agronomique (INRA)-Centre international d'études supérieures en sciences agronomiques (Montpellier SupAgro)-École pratique des hautes études (EPHE)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD [France-Sud])-Institut national d’études supérieures agronomiques de Montpellier (Montpellier SupAgro), United States Department of Agriculture - USDA (USA), Smithsonian Institution, Carnegie Museum of Natural History, Friedrich-Schiller-Universität Jena, Biodiversité, Gènes et Communautés, Goethe-Universität Frankfurt am Main-Senckenberg Gesellschaft für Naturforschung, University of Natural Resources and Applied Life Sciences (BOKU), Florida International University (FIU), Université Catholique de Louvain (UCL), Stanford University [Stanford], Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Institut Ecologie et Environnement (INEE), Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS)-Observatoire des Sciences de l'Univers de Rennes (OSUR)-Centre National de la Recherche Scientifique (CNRS), University of Tasmania (UTAS), Institut National de la Recherche Agronomique (INRA)-Ecole Nationale Supérieure Agronomique de Toulouse-Institut National Polytechnique (Toulouse) (Toulouse INP), Charles University [Prague], Ghent University [Belgium] (UGENT), Helmholtz Zentrum für Umweltforschung (UFZ), Hokkaido University, Technical University of Munich (TUM), Wageningen University and Research Centre [Wageningen] (WUR), Georg-August-Universität Göttingen, Western Sydney University (UWS), Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-Institut de Recherche pour le Développement (IRD)-Centre international d'études supérieures en sciences agronomiques (Montpellier SupAgro)-Institut national d’études supérieures agronomiques de Montpellier (Montpellier SupAgro)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Département de Biologie, Université de Sherbrooke, Sherbrooke, QC, Canada, Université de Sherbrooke, Masaryk University, Czech Academy of Sciences [Prague] (ASCR), Natural Resources Institute Finland, Landcare Research [Lincoln], Université de Montréal [Montréal], Université Libre de Bruxelles [Bruxelles] (ULB), Centre National de la Recherche Scientifique (CNRS)-Ministère de l'Europe et des Affaires étrangères (MEAE), French Institute of Pondicherry (IFP), Normal Zhejiang University, Estonian University of Life Sciences, Institute of Biology Bucharest, Romanian Academy, VU University Amsterdam, Astronomical Institute of the Czech Academy of Sciences, Technische Universität München [München] (TUM), University of Parma, Cardiff School of Social Sciences, University of Cardiff, University of Minnesota [Twin Cities], Manaaki Whenua Landcare Research, Université Côte d'Azur (UCA)-Université Côte d'Azur (UCA)-Institut National de la Santé et de la Recherche Médicale (INSERM), Brookhaven National Laboratory [Upton] (BNL), Stony Brook University [SUNY] (SBU), University of Zürich [Zürich] (UZH), Algoma University [Canada], University of Goettingen, University of Wuerzburg, University of Würzburg, AFSSA, Sherbrooke University, University of Lisbon, Department of Biology (University of Florida), Florida Museum of Natural History, Technical University in Zvolen, University of Zvolen, Fac Forestry & Wood Sci, Université du Québec à Montréal (UQAM), Bioversity International, Consultative Group on International Agricultural Research [CGIAR], Université Clermont Auvergne (UCA), Vrije Universiteit [Brussels] (VUB), University of Tsukuba, Kattge, Jen, Bönisch, Gerhard, Díaz, Sandra, Lavorel, Sandra, Prentice, Iain Colin, Leadley, Paul, Tautenhahn, Susanne, Werner, Gijsbert D A, Aakala, Tuoma, Abedi, Mehdi, Acosta, Alicia Teresa Rosario, Adamidis, George C, Adamson, Kairi, Aiba, Masahiro, Albert, Cécile H, Alcántara, Julio M, Alcázar C, Carolina, Aleixo, Izabela, Ali, Hamada, Amiaud, Bernard, Ammer, Christian, Amoroso, Mariano M, Anand, Madhur, Anderson, Carolyn, Anten, Niel, Antos, Joseph, Apgaua, Deborah Mattos Guimarãe, Ashman, Tia-Lynn, Asmara, Degi Harja, Asner, Gregory P, Aspinwall, Michael, Atkin, Owen, Aubin, Isabelle, Baastrup-Spohr, Lar, Bahalkeh, Khadijeh, Bahn, Michael, Baker, Timothy, Baker, William J, Bakker, Jan P, Baldocchi, Denni, Baltzer, Jennifer, Banerjee, Arindam, Baranger, Anne, Barlow, Jo, Barneche, Diego R, Baruch, Zdravko, Bastianelli, Deni, Battles, John, Bauerle, William, Bauters, Marijn, Bazzato, Erika, Beckmann, Michael, Beeckman, Han, Beierkuhnlein, Carl, Bekker, Renee, Belfry, Gavin, Belluau, Michael, Beloiu, Mirela, Benavides, Raquel, Benomar, Lahcen, Berdugo-Lattke, Mary Lee, Berenguer, Erika, Bergamin, Rodrigo, Bergmann, Joana, Bergmann Carlucci, Marco, Berner, Logan, Bernhardt-Römermann, Marku, Bigler, Christof, Bjorkman, Anne D, Blackman, Chri, Blanco, Carolina, Blonder, Benjamin, Blumenthal, Dana, Bocanegra-González, Kelly T, Boeckx, Pascal, Bohlman, Stephanie, Böhning-Gaese, Katrin, Boisvert-Marsh, Laura, Bond, William, Bond-Lamberty, Ben, Boom, Arnoud, Boonman, Coline C F, Bordin, Kauane, Boughton, Elizabeth H, Boukili, Vanessa, Bowman, David M J S, Bravo, Sandra, Brendel, Marco Richard, Broadley, Martin R, Brown, Kerry A, Bruelheide, Helge, Brumnich, Federico, Bruun, Hans Henrik, Bruy, David, Buchanan, Serra W, Bucher, Solveig Franziska, Buchmann, Nina, Buitenwerf, Robert, Bunker, Daniel E, Bürger, Jana, Burrascano, Sabina, Burslem, David F R P, Butterfield, Bradley J, Byun, Chaeho, Marques, Marcia, Scalon, Marina C, Caccianiga, Marco, Cadotte, Marc, Cailleret, Maxime, Camac, Jame, Camarero, Jesús Julio, Campany, Courtney, Campetella, Giandiego, Campos, Juan Antonio, Cano-Arboleda, Laura, Canullo, Roberto, Carbognani, Michele, Carvalho, Fabio, Casanoves, Fernando, Castagneyrol, Bastien, Catford, Jane A, Cavender-Bares, Jeannine, Cerabolini, Bruno E L, Cervellini, Marco, Chacón-Madrigal, Eduardo, Chapin, Kenneth, Chapin, F Stuart, Chelli, Stefano, Chen, Si-Chong, Chen, Anping, Cherubini, Paolo, Chianucci, Francesco, Choat, Brendan, Chung, Kyong-Sook, Chytrý, Milan, Ciccarelli, Daniela, Coll, Lluí, Collins, Courtney G, Conti, Luisa, Coomes, David, Cornelissen, Johannes H C, Cornwell, William K, Corona, Piermaria, Coyea, Marie, Craine, Joseph, Craven, Dylan, Cromsigt, Joris P G M, Csecserits, Anikó, Cufar, Katarina, Cuntz, Matthia, da Silva, Ana Carolina, Dahlin, Kyla M, Dainese, Matteo, Dalke, Igor, Dalle Fratte, Michele, Dang-Le, Anh Tuan, Danihelka, Jirí, Dannoura, Masako, Dawson, Samantha, de Beer, Arend Jacobu, De Frutos, Angel, De Long, Jonathan R, Dechant, Benjamin, Delagrange, Sylvain, Delpierre, Nicola, Derroire, Géraldine, Dias, Arildo S, Diaz-Toribio, Milton Hugo, Dimitrakopoulos, Panayiotis G, Dobrowolski, Mark, Doktor, Daniel, Dřevojan, Pavel, Dong, Ning, Dransfield, John, Dressler, Stefan, Duarte, Leandro, Ducouret, Emilie, Dullinger, Stefan, Durka, Walter, Duursma, Remko, Dymova, Olga, E-Vojtkó, Anna, Eckstein, Rolf Lutz, Ejtehadi, Hamid, Elser, Jame, Emilio, Thaise, Engemann, Kristine, Erfanian, Mohammad Bagher, Erfmeier, Alexandra, Esquivel-Muelbert, Adriane, Esser, Gerd, Estiarte, Marc, Domingues, Tomas F, Fagan, William F, Fagúndez, Jaime, Falster, Daniel S, Fan, Ying, Fang, Jingyun, Farris, Emmanuele, Fazlioglu, Fatih, Feng, Yanhao, Fernandez-Mendez, Fernando, Ferrara, Carlotta, Ferreira, Joice, Fidelis, Alessandra, Finegan, Bryan, Firn, Jennifer, Flowers, Timothy J, Flynn, Dan F B, Fontana, Veronika, Forey, Estelle, Forgiarini, Cristiane, François, Loui, Frangipani, Marcelo, Frank, Dorothea, Frenette-Dussault, Cedric, Freschet, Grégoire T, Fry, Ellen L, Fyllas, Nikolaos M, Mazzochini, Guilherme G, Gachet, Sophie, Gallagher, Rachael, Ganade, Gislene, Ganga, Francesca, García-Palacios, Pablo, Gargaglione, Verónica, Garnier, Eric, Garrido, Jose Lui, de Gasper, André Luí, Gea-Izquierdo, Guillermo, Gibson, David, Gillison, Andrew N, Giroldo, Aelton, Glasenhardt, Mary-Claire, Gleason, Sean, Gliesch, Mariana, Goldberg, Emma, Göldel, Bastian, Gonzalez-Akre, Erika, Gonzalez-Andujar, Jose L, González-Melo, André, González-Robles, Ana, Graae, Bente Jessen, Granda, Elena, Graves, Sarah, Green, Walton A, Gregor, Thoma, Gross, Nicola, Guerin, Greg R, Günther, Angela, Gutiérrez, Alvaro G, Haddock, Lillie, Haines, Anna, Hall, Jefferson, Hambuckers, Alain, Han, Wenxuan, Harrison, Sandy P, Hattingh, Wesley, Hawes, Joseph E, He, Tianhua, He, Pengcheng, Heberling, Jacob Mason, Helm, Aveliina, Hempel, Stefan, Hentschel, Jörn, Hérault, Bruno, Hereş, Ana-Maria, Herz, Katharina, Heuertz, Myriam, Hickler, Thoma, Hietz, Peter, Higuchi, Pedro, Hipp, Andrew L, Hirons, Andrew, Hock, Maria, Hogan, James Aaron, Holl, Karen, Honnay, Olivier, Hornstein, Daniel, Hou, Enqing, Hough-Snee, Nate, Hovstad, Knut Ander, Ichie, Tomoaki, Igić, Bori, Illa, Estela, Isaac, Marney, Ishihara, Masae, Ivanov, Leonid, Ivanova, Larissa, Iversen, Colleen M, Izquierdo, Jordi, Jackson, Robert B, Jackson, Benjamin, Jactel, Hervé, Jagodzinski, Andrzej M, Jandt, Ute, Jansen, Steven, Jenkins, Thoma, Jentsch, Anke, Jespersen, Jens Rasmus Plantener, Jiang, Guo-Feng, Johansen, Jesper Liengaard, Johnson, David, Jokela, Eric J, Joly, Carlos Alfredo, Jordan, Gregory J, Joseph, Grant Stuart, Junaedi, Decky, Junker, Robert R, Justes, Eric, Kabzems, Richard, Kane, Jeffrey, Kaplan, Zdenek, Kattenborn, Teja, Kavelenova, Lyudmila, Kearsley, Elizabeth, Kempel, Anne, Kenzo, Tanaka, Kerkhoff, Andrew, Khalil, Mohammed I, Kinlock, Nicole L, Kissling, Wilm Daniel, Kitajima, Kaoru, Kitzberger, Thoma, Kjøller, Rasmu, Klein, Tamir, Kleyer, Michael, Klimešová, Jitka, Klipel, Joice, Kloeppel, Brian, Klotz, Stefan, Knops, Johannes M H, Kohyama, Takashi, Koike, Fumito, Kollmann, Johanne, Komac, Benjamin, Komatsu, Kimberly, König, Christian, Kraft, Nathan J B, Kramer, Koen, Kreft, Holger, Kühn, Ingolf, Kumarathunge, Dushan, Kuppler, Jona, Kurokawa, Hiroko, Kurosawa, Yoko, Kuyah, Shem, Laclau, Jean-Paul, Lafleur, Benoit, Lallai, Erik, Lamb, Eric, Lamprecht, Andrea, Larkin, Daniel J, Laughlin, Daniel, Le Bagousse-Pinguet, Yoann, le Maire, Guerric, le Roux, Peter C, le Roux, Elizabeth, Lee, Tali, Lens, Frederic, Lewis, Simon L, Lhotsky, Barbara, Li, Yuanzhi, Li, Xine, Lichstein, Jeremy W, Liebergesell, Mario, Lim, Jun Ying, Lin, Yan-Shih, Linares, Juan Carlo, Liu, Chunjiang, Liu, Daijun, Liu, Udayangani, Livingstone, Stuart, Llusià, Joan, Lohbeck, Madelon, López-García, Álvaro, Lopez-Gonzalez, Gabriela, Lososová, Zdeňka, Louault, Frédérique, Lukács, Balázs A, Lukeš, Petr, Luo, Yunjian, Lussu, Michele, Ma, Siyan, Maciel Rabelo Pereira, Camilla, Mack, Michelle, Maire, Vincent, Mäkelä, Annikki, Mäkinen, Harri, Malhado, Ana Claudia Mende, Mallik, Azim, Manning, Peter, Manzoni, Stefano, Marchetti, Zuleica, Marchino, Luca, Marcilio-Silva, Viniciu, Marcon, Eric, Marignani, Michela, Markesteijn, Lar, Martin, Adam, Martínez-Garza, Cristina, Martínez-Vilalta, Jordi, Mašková, Tereza, Mason, Kelly, Mason, Norman, Massad, Tara Joy, Masse, Jacynthe, Mayrose, Itay, Mccarthy, Jame, Mccormack, M Luke, Mcculloh, Katherine, Mcfadden, Ian R, Mcgill, Brian J, Mcpartland, Mara Y, Medeiros, Juliana S, Medlyn, Belinda, Meerts, Pierre, Mehrabi, Zia, Meir, Patrick, Melo, Felipe P L, Mencuccini, Maurizio, Meredieu, Céline, Messier, Julie, Mészáros, Ilona, Metsaranta, Juha, Michaletz, Sean T, Michelaki, Chrysanthi, Migalina, Svetlana, Milla, Ruben, Miller, Jesse E D, Minden, Vanessa, Ming, Ray, Mokany, Karel, Moles, Angela T, Molnár, Attila, Molofsky, Jane, Molz, Martin, Montgomery, Rebecca A, Monty, Arnaud, Moravcová, Lenka, Moreno-Martínez, Alvaro, Moretti, Marco, Mori, Akira S, Mori, Shigeta, Morris, Dave, Morrison, Jane, Mucina, Ladislav, Mueller, Sandra, Muir, Christopher D, Müller, Sandra Cristina, Munoz, Françoi, Myers-Smith, Isla H, Myster, Randall W, Nagano, Masahiro, Naidu, Shawna, Narayanan, Ayyappan, Natesan, Balachandran, Negoita, Luka, Nelson, Andrew S, Neuschulz, Eike Lena, Ni, Jian, Niedrist, Georg, Nieto, Jhon, Niinemets, Ülo, Nolan, Rachael, Nottebrock, Henning, Nouvellon, Yann, Novakovskiy, Alexander, Nystuen, Kristin Odden, O'Grady, Anthony, O'Hara, Kevin, O'Reilly-Nugent, Andrew, Oakley, Simon, Oberhuber, Walter, Ohtsuka, Toshiyuki, Oliveira, Ricardo, Öllerer, Kinga, Olson, Mark E, Onipchenko, Vladimir, Onoda, Yusuke, Onstein, Renske E, Ordonez, Jenny C, Osada, Noriyuki, Ostonen, Ivika, Ottaviani, Gianluigi, Otto, Sarah, Overbeck, Gerhard E, Ozinga, Wim A, Pahl, Anna T, Paine, C E Timothy, Pakeman, Robin J, Papageorgiou, Aristotelis C, Parfionova, Evgeniya, Pärtel, Meeli, Patacca, Marco, Paula, Susana, Paule, Juraj, Pauli, Harald, Pausas, Juli G, Peco, Begoña, Penuelas, Josep, Perea, Antonio, Peri, Pablo Lui, Petisco-Souza, Ana Carolina, Petraglia, Alessandro, Petritan, Any Mary, Phillips, Oliver L, Pierce, Simon, Pillar, Valério D, Pisek, Jan, Pomogaybin, Alexandr, Poorter, Hendrik, Portsmuth, Angelika, Poschlod, Peter, Potvin, Catherine, Pounds, Devon, Powell, A Shafer, Power, Sally A, Prinzing, Andrea, Puglielli, Giacomo, Pyšek, Petr, Raevel, Valerie, Rammig, Anja, Ransijn, Johanne, Ray, Courtenay A, Reich, Peter B, Reichstein, Marku, Reid, Douglas E B, Réjou-Méchain, Maxime, de Dios, Victor Resco, Ribeiro, Sabina, Richardson, Sarah, Riibak, Kersti, Rillig, Matthias C, Riviera, Fiamma, Robert, Elisabeth M R, Roberts, Scott, Robroek, Bjorn, Roddy, Adam, Rodrigues, Arthur Viniciu, Rogers, Alistair, Rollinson, Emily, Rolo, Victor, Römermann, Christine, Ronzhina, Dina, Roscher, Christiane, Rosell, Julieta A, Rosenfield, Milena Fermina, Rossi, Christian, Roy, David B, Royer-Tardif, Samuel, Rüger, Nadja, Ruiz-Peinado, Ricardo, Rumpf, Sabine B, Rusch, Graciela M, Ryo, Masahiro, Sack, Lawren, Saldaña, Angela, Salgado-Negret, Beatriz, Salguero-Gomez, Roberto, Santa-Regina, Ignacio, Santacruz-García, Ana Carolina, Santos, Joaquim, Sardans, Jordi, Schamp, Brandon, Scherer-Lorenzen, Michael, Schleuning, Matthia, Schmid, Bernhard, Schmidt, Marco, Schmitt, Sylvain, Schneider, Julio V, Schowanek, Simon D, Schrader, Julian, Schrodt, Franziska, Schuldt, Bernhard, Schurr, Frank, Selaya Garvizu, Galia, Semchenko, Marina, Seymour, Colleen, Sfair, Julia C, Sharpe, Joanne M, Sheppard, Christine S, Sheremetiev, Serge, Shiodera, Satomi, Shipley, Bill, Shovon, Tanvir Ahmed, Siebenkäs, Alrun, Sierra, Carlo, Silva, Vasco, Silva, Mateu, Sitzia, Tommaso, Sjöman, Henrik, Slot, Martijn, Smith, Nicholas G, Sodhi, Darwin, Soltis, Pamela, Soltis, Dougla, Somers, Ben, Sonnier, Grégory, Sørensen, Mia Vedel, Sosinski, Enio Egon, Soudzilovskaia, Nadejda A, Souza, Alexandre F, Spasojevic, Marko, Sperandii, Marta Gaia, Stan, Amanda B, Stegen, Jame, Steinbauer, Klau, Stephan, Jörg G, Sterck, Frank, Stojanovic, Dejan B, Strydom, Tanya, Suarez, Maria Laura, Svenning, Jens-Christian, Svitková, Ivana, Svitok, Marek, Svoboda, Miroslav, Swaine, Emily, Swenson, Nathan, Tabarelli, Marcelo, Takagi, Kentaro, Tappeiner, Ulrike, Tarifa, Rubén, Tauugourdeau, Simon, Tavsanoglu, Cagatay, Te Beest, Mariska, Tedersoo, Leho, Thiffault, Nelson, Thom, Dominik, Thomas, Evert, Thompson, Ken, Thornton, Peter E, Thuiller, Wilfried, Tichý, Lubomír, Tissue, David, Tjoelker, Mark G, Tng, David Yue Phin, Tobias, Joseph, Török, Péter, Tarin, 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Landcare Research, Institut de recherche en biologie végétale, Université de Montréal, Tel Aviv University, The University of Queensland, CSIRO, Manaaki Whenua – Landcare Research, Université Libre de Bruxelles, The Australian National University, The University of Edinburgh, Universidade Federal de Pernambuco (UFPE), ICREA, UEFP, University of Waterloo, Tulipan s/n, Vrije Universiteit Brussel, University of Illinois at Urbana-Champaign, University of Vermont, Centre for Northern Forest Ecosystem Research, Matieland, University of Freiburg, University of Hawai'i, Université Grenoble-Alpes, French Institute of Pondicherry, Oklahoma State University, Charles Darwin Research Station, University of Idaho, Instituto de Investigación de Recursos Biológicos Alexander von Humboldt, Universidad Distrital Francisco José de Caldas, NORD University, NTNU, Gifu University, Romanian Academy, Tercer Circuito s/n de Ciudad Universitaria, Universidad Nacional Autónoma de México, Moscow Lomonosov State University, Universidad de las Américas, Wageningen Environmental Research, Technische Universität München, University of New England, Democritus University of Thrace, Universidad Austral de Chile, Desertification Research Center (CIDE-CSIC), Universidad Autónoma de Madrid, Instituto Nacional de Tecnología Agropecuaria (INTA), National Institute for Research-Development in Forestry, University of Regensburg, McGill University, Morton Arboretum, Université Rennes 1/CNRS, Université Paul Valéry, Southwest University of Science and Technology, Universitat de Lleida, Universidade Federal do Acre, Manaaki Whenua-Landcare Research, Centre for Ecological Research and Forestry Applications (CREAF), Royal Museum for Central-Africa (RMCA), Mississippi State University, Radboud University Nijmegen, Yale University, Brookhaven National Laboratory, Ciudad Universitaria, University of Zurich, Chastè Planta-Wildenberg, Centre for Ecology & Hydrology (CEH), Canadian Forest Service, University of Valladolid-INIA, University of Lausanne, Norwegian Institute for Nature Research, Oxford University, Instituto de Recursos Naturales y Agrobiología de Salamanca (IRNASA-CSIC), Universidade de Coimbra, Senckenberg Biodiversität und Klima Forschungszentrum (SBiK-F), Palmengarten der Stadt Frankfurt am Main, Research Institute for Humanity and Nature, University of Regina, Technische Universität Ilmenau, Università degli Studi di Padova, Gothenburg Botanical Garden, Texas Tech University, Archbold Biological Station, Universidade Federal do Rio Grande do Norte, Slovak Academy of Sciences, Czech University of Life Sciences, Estación Experimental de Zonas Áridas (CSIC), CIRAD-UMR SELMET-PZZS, Hacettepe University, Utrecht University, Canadian Wood Fibre Centre, University of Sheffield, Silwood Park, MTA-DE Lendület Functional and Restoration Ecology Research Group, University of Delaware, UMR PIAF, MTA-TKI Biodiversity and Ecosystem Services Research Group, University of Illinois, Botanical Garden of Ural Branch of Russian Academy of Sciences, University of New Hampshire, National University of Singapore, Edinburgh University, Florida Institute of Technology, University of Konstanz, Taizhou University, University of Erlangen-Nuremberg, Universidad de Concepcion, Bulgarian Academy of Sciences, Museu Paraense Emilio Goeldi, Universidad de las Fuerzas Armadas (ESPE), Goa University, Pondicherry University, Carl von Ossietzky University of Oldenburg, Cambridge Conservation Initiative, Tsinghua University, Chinese Academy of Forestry, Fujian Normal University, Vrije Universiteit Amsterdam, Maritime and Science Technology Academy, University of Winnipeg, King Saud University, University of California – Irvine, U. S. Geological Survey, Duke University, NSW Department of Primary Industries, SUNY-College of Environmental Science and Forestry, Sorbonne-Université, Laboratório de Ecologia Vegetal (LEVEG), George Washington University, National Taiwan University, Institut National Polytechnique Félix Houphouët-Boigny (INP-HB), University Oldenburg, and Biyoloji

Subjects
[SDE] Environmental Sciences, LIFE-HISTORY, Geography & travel, WOOD DENSITY, plant trait, Biodiversity & Conservation, 05 Environmental Sciences, Growth, 580 Plants (Botany), COMMUNITY COMPOSITION, ROOT TRAITS, Biologiska vetenskaper, Ecological modeling, data coverage, data integration, data representativeness, functional diversity, plant traits, TRY plant trait database, Biodiversity, Ecology, Plants, Access to Information, Ecosystem, data representativene, ddc:910, General Environmental Science, Global and Planetary Change, GLOBAL PATTERNS, food and beverages, LEAF PHOTOSYNTHETIC TRAITS, Biological Sciences, CAVElab, Data processing, ddc:580, [SDE]Environmental Sciences, Biodiversity Conservation, Life Sciences & Biomedicine, INCLINATION ANGLE DISTRIBUTION, Environmental Sciences & Ecology, Ecology and Environment, Database, LITTER DECOMPOSITION, ddc:570, Datenintegration, Environmental Chemistry, DDC 004 / Data processing & computer science, Intraspecific competition, Data integration (Computer science), Science & Technology, Biology and Life Sciences, Plant, 06 Biological Sciences, Environmental factor, Nutrient Network, Biology and Microbiology, FUNCTIONAL TRAITS, DDC 580 / Botanical sciences, Earth and Environmental Sciences, ddc:004, [SDE.BE]Environmental Sciences/Biodiversity and Ecology, Environmental Sciences, RELATIVE GROWTH-RATE
Abstract

Plant traits—the morphological, anatomical, physiological, biochemical and phenological characteristics of plants—determine how plants respond to environmental factors, affect other trophic levels, and influence ecosystem properties and their benefits and detriments to people. Plant trait data thus represent the basis for a vast area of research spanning from evolutionary biology, community and functional ecology, to biodiversity conservation, ecosystem and landscape management, restoration, biogeography and earth system modelling. Since its foundation in 2007, the TRY database of plant traits has grown continuously. It now provides unprecedented data coverage under an open access data policy and is the main plant trait database used by the research community worldwide. Increasingly, the TRY database also supports new frontiers of trait-based plant research, including the identification of data gaps and the subsequent mobilization or measurement of new data. To support this development, in this article we evaluate the extent of the trait data compiled in TRY and analyse emerging patterns of data coverage and representativeness. Best species coverage is achieved for categorical traits—almost complete coverage for ‘plant growth form’. However, most traits relevant for ecology and vegetation modelling are characterized by continuous intraspecific variation and trait–environmental relationships. These traits have to be measured on individual plants in their respective environment. Despite unprecedented data coverage, we observe a humbling lack of completeness and representativeness of these continuous traits in many aspects. We, therefore, conclude that reducing data gaps and biases in the TRY database remains a key challenge and requires a coordinated approach to data mobilization and trait measurements. This can only be achieved in collaboration with other initiatives., publishedVersion

Published
2020

27. Randomized trial of angiotensin II-receptor blocker vs. dihydropiridine calcium channel blocker in the treatment of paroxysmal atrial fibrillation with hypertension (J-RHYTHM II Study)

Author

Yamashita, Takeshi, Inoue, Hiroshi, Okumura, Ken, Kodama, Itsuo, Aizawa, Yoshifusa, Atarashi, Hirotsugu, Ohe, Tohru, Ohtsu, Hiroshi, Kato, Takao, Kamakura, Shiro, Kumagai, Koichiro, Kurachi, Yoshihisa, Koretsune, Yukihiro, Saikawa, Tetsunori, Sakurai, Masayuki, Sato, Toshiaki, Sugi, Kaoru, Nakaya, Haruaki, Hirai, Makoto, Hirayama, Atsushi, Fukatani, Masahiko, Mitamura, Hideo, Yamazaki, Tsutomu, Watanabe, Eiichi, Ogawa, Satoshi, Katoh, T, Igawa, O, Matsumoto, N, Yamashita, T, Kaneko, Y, Watanabe, E, Ogawa, S, Osaka, T, Fujii, E, Niwano, S, Yoshioka, K, Kato, M, Okazaki, O, Kusano, K, Okuyama, Y, Furushima, H, Suzuki, M, Noda, T, Kawara, T, Sato, T, Kamakura, S, Endoh, Y, Kumagai, K, Hiyoshi, Y, Ishiyama, T, Ohtsuka, T, Matsumoto, M, Chishaki, A, Shinohara, T, Shirayama, T, Koretsune, Y, Yokoyama, E, Ajiki, K, Fujio, K, Sugi, K, Yamakawa, T, Yusu, S, Inoue, H, Kawamura, Y, Hayano, M, Date, T, Mizusawa, Y, Kobayashi, Y, Satomi, K, Imai, Y, Atarashi, H, Fukunami, M, Yokoshiki, H, Betsuyaku, T, Okumura, K, Takeda, H, Matsumoto, K, Okishige, K, Tagawa, M, Hirai, M, and Okazaki, H

Published
2011
Full Text
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32. Growth Rate of Crystal Surfaces with Several Dislocation Centers

Author

Ohtsuka, T., Tsai, Yen-Hsi Richard, Giga, Y., Ohtsuka, T., Tsai, Yen-Hsi Richard, and Giga, Y.

Abstract

We studied analytically and numerically the growth rate of a crystal surface growing by several screw dislocations. We observed some discrepancy between the growth rates computed by our level set method (J. Sci. Comput. 2015, 62., QC 20180320

Published
2018
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40. Multifocal Pancreatic Ductal Adenocarcinomas Concomitant with Intraductal Papillary Mucinous Neoplasms of the Pancreas Detected by Intraoperative Pancreatic Juice Cytology. A Case Report

Author

Mori, Y., Ohtsuka, T., Tsutsumi, K., Yasui, T., Yoshihiko Sadakari, Ueda, J., Takahata, S., Nakamura, M., and Tanaka, M.

Subjects
Male, Mucinous, and serous, endocrine system diseases, Cytodiagnosis, Carcinoma, Carcinoma, Pancreatic Ductal, Neoplasms, Cystic, Mucinous, and Serous, Pancreatectomy, Pancreatic Juice /cytology, Middle Aged, Adenocarcinoma, Mucinous, Carcinoma, Papillary, Neoplasms, Multiple Primary, Pancreatic Neoplasms, Cystic, Pancreatic Juice, Monitoring, Intraoperative, Neoplasms, Pancreatic juice/cytology, Humans, Pancreatic ductal
Abstract

Context Intraductal papillary mucinous neoplasms (IPMNs) of the pancreas have been detected with increasing frequency as a result of the progression of diagnostic modalities. Recently, invasive ductal carcinoma of the pancreas concomitant with IPMNs has been the focus of attention. Case report We report the case of a 57-year-old man with multifocal ductal carcinomas of the pancreas concomitant with IPMNs detected by intraoperative cytology. During a follow-up for branch duct IPMNs, a stenotic lesion of the main duct in the pancreatic body was found by ERCP, and brush cytology of the stenosis revealed an adenocarcinoma. A distal pancreatectomy was proposed; however, intraoperative pancreatic juice cytology from the pancreatic head also revealed adenocarcinoma, and a total pancreatectomy was finally carried out. Pathological examination of the resected specimen showed multifocal ductal carcinomas and IPMNs in the distal pancreas, and invasive ductal carcinoma in the pancreatic head which had not been detected by preoperative imaging studies. Conclusions Surgeons should be aware of the possibility of multifocal carcinomas in patients with concomitant IPMNs. Intraoperative pancreatic juice cytology should always be performed in order to confirm the absence of carcinoma in the pancreas to be left in place after planned resection. Image: Schematic representation of the location of IPMNs and non-invasive and invasive ductal carcinomas., JOP. Journal of the Pancreas, Vol 11, No 4 (2010): July - p. 299-422

Published
2010

48. In Vitro and In Vivo Evaluation of Zr-89-DS-8273a as a Theranostic for Anti-Death Receptor 5 Therapy

Author

Burvenich, IJG, Lee, F-T, Guo, N, Gan, HK, Rigopoulos, A, Parslow, AC, O'Keefe, GJ, Gong, SJ, Tochon-Danguy, H, Rudd, SE, Dormelly, PS, Kotsuma, M, Ohtsuka, T, Senaldi, G, Scott, AM, Burvenich, IJG, Lee, F-T, Guo, N, Gan, HK, Rigopoulos, A, Parslow, AC, O'Keefe, GJ, Gong, SJ, Tochon-Danguy, H, Rudd, SE, Dormelly, PS, Kotsuma, M, Ohtsuka, T, Senaldi, G, and Scott, AM

Abstract

Background: DS-8273a, an anti-human death receptor 5 (DR5) agonistic antibody, has cytotoxic activity against human cancer cells and induces apoptosis after specific binding to DR5. DS-8273a is currently being used in clinical Phase I trials. This study evaluated the molecular imaging of DR5 expression in vivo in mouse tumor models using SPECT/CT and PET/MRI, as a tool for drug development and trial design. Methods: DS-8273a was radiolabeled with indium-111 and zirconium-89. Radiochemical purity, immunoreactivity, antigen binding affinity and serum stability were assessed in vitro. In vivo biodistribution and pharmacokinetic studies were performed, including SPECT/CT and PET/MR imaging. A dose-escalation study using a PET/MR imaging quantitative analysis was also performed to determine DR5 receptor saturability in a mouse model. Results:111In-CHX-A″-DTPA-DS-8273a and 89Zr-Df-Bz-NCS-DS-8273a showed high immunoreactivity (100%), high serum stability, and bound to DR5 expressing cells with high affinity (Ka, 1.02-1.22 × 1010 M-1). The number of antibodies bound per cell was 32,000. In vivo biodistribution studies showed high and specific uptake of 111In-CHX-A″-DTPA-DS-8273a and 89Zr-Df-Bz-NCS-DS-8273a in DR5 expressing COLO205 xenografts, with no specific uptake in normal tissues or in DR5-negative CT26 xenografts. DR5 receptor saturation was observed in vivo by biodistribution studies and quantitative PET/MRI analysis. Conclusion:89Zr-Df-Bz-NCS-DS-8273a is a potential novel PET imaging reagent for human bioimaging trials, and can be used for effective dose assessment and patient response evaluation in clinical trials.

Published
2016

50. Influence of beta-FeSi2 particle size and Si growth rate on 1.5 µm photoluminescence from Si/beta-FeSi2-particles/Si structures grown by molecular-beam epitaxy

Author

Ozawa, Y., Ohtsuka, T., Li, Cheng, Suemasu, T., and Hasegawa, F.

Subjects
ComputingMethodologies_DOCUMENTANDTEXTPROCESSING
Abstract

application/pdf, Si/beta-FeSi2-particles/Si structures have been fabricated by reactive deposition epitaxy for beta-FeSi2 and molecular-beam epitaxy (MBE) for Si, and the influence of the size of the beta-FeSi2 particle and the MBE-Si growth rate for embedding the beta-FeSi2 in Si on 1.5-µm photoluminescence (PL) intensity of beta-FeSi2 was investigated. The 1.5-µm PL intensity was observed to increase with the size of the beta-FeSi2 particle, but the broad background luminescence, ranging from 1.2 to 1.4 µm, also increased. Transmission electron microscopy observation suggested that the broad luminescence was due to the dislocations induced in the Si matrix when the size of the embedded beta-FeSi2 particles was too large. Furthermore, the 1.5-µm PL intensity was observed to be strongly affected by MBE-Si growth rate. This is thought to be due to the strain induced in the beta-FeSi2 particles upon being embedded in the Si.

Published
2004

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