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259 results on '"Ohdaira, Hironori"'

21. Interaction of Vitamin D Supplements and Marine n -3 Fatty Acids on Digestive Tract Cancer Prognosis.

Author

Fukuzato, Soichiro, Ohdaira, Hironori, Suzuki, Yutaka, and Urashima, Mitsuyoshi

Abstract

A meta-analysis suggested that marine n-3 polyunsaturated fatty acids (PUFAs), e.g., eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), might reduce cancer mortality. However, a randomized clinical trial of marine n-3 PUFA and vitamin D supplementation failed to verify this benefit. This study aimed to investigate the potential interaction between vitamin D supplementation and serum EPA and DHA levels. This post hoc analysis of the AMATERASU trial (UMIN000001977), a randomized controlled trial (RCT), included 302 patients with digestive tract cancers divided into two subgroups stratified by median serum levels of EPA + DHA into higher and lower halves. The 5-year relapse-free survival (RFS) rate was significantly higher in the higher half (80.9%) than the lower half (67.8%; hazard ratio (HR), 2.15; 95% CI, 1.29–3.59). In the patients in the lower EPA + DHA group, the 5-year RFS was significantly higher in the vitamin D (74.9%) than the placebo group (49.9%; HR, 0.43; 95% CI, 0.24–0.78). Conversely, vitamin D had no effect in the higher half, suggesting that vitamin D supplementation only had a significant interactive effect on RFS in the lower half (p for interaction = 0.03). These results suggest that vitamin D supplementation may reduce the risk of relapse or death by interacting with marine n-3 PUFAs. [ABSTRACT FROM AUTHOR]

Published
2024
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22. Primary small‐cell carcinoma in the lung was found after the cold snare polypectomy of the small metastatic lesion in the cecum: A case report

Author

Suto, Daisuke, primary, Yoshida, Masashi, additional, Yamada, Hidehiko, additional, Akita, Takayuki, additional, Osawa, Yosuke, additional, Sato, Kiichi, additional, Otake, Takaaki, additional, Nakazato, Yoshimasa, additional, Arakawa, Nobuhito, additional, Ohdaira, Hironori, additional, Suzuki, Yutaka, additional, and Kohgo, Yutaka, additional

Published
2023
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25. A technique for esophagojejunostomy following robot assisted gastrectomy: a liner stapler and barbed suture device based technique: A case series

Author

Ohdaira, Hironori, primary, Kamada, Teppei, additional, Takahashi, Junji, additional, Nakashima, Keigo, additional, Nakaseko, Yuichi, additional, Ishigaki, Takayuki, additional, Suzuki, Norihiko, additional, Yoshida, Masashi, additional, Yamanouchi, Eigoro, additional, and Suzuki, Yutaka, additional

Published
2023
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