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7. Time from injury to hip-fracture surgery in low-income and middle-income regions: a secondary analysis of data from the International Orthopaedic Multicentre Study in Fracture Care (INORMUS)

Author

Guyatt, Gordon, Petrisor, Brad, Thabane, Lehana, Boniface, Respicious, Browner, Bruce, Pollak, Andrew, Slobogean, Gerard, Schemitsch, Emil, McKay, Paula, Tai, Kerry, Heels-Ansdell, Diane, Buckingham, Lisa, Norton, Robyn, Zhang, Jing, Parveen, Samina, Bhaumik, Soumyadeep, Morshed, Saam, Mackechnie, Madeline C., Zhang, Zhentao, Ma, Yinghua, Qin, Yanguo, Hu, Sanbao, Qi, Baochang, Dai, Wenjie, Cai, Xinyu, Rui, Gang, Chen, Hua, Shetty, Vijay, Dumbre Patil, Sampat, Patil, Sanjay, Shrivastava, Sandeep, Mittal, Ravi, Jepegnanam, Thilak Samuel, Mahajan, Anupam, Chhabra, Harvinder Singh, N, Rajagopalan, Amaravathi, Rajkumar S., Dhillon, Mandeep S., Chase, Asolie, Bhavsar, Neel M., Saadat, Soheil, Byanjankar, Subin, Qadir, Raja Irfan, Tabu, Irewin Alagar, Ponggsamakthai, Wanjak, Sa-ngasoongsong, Paphon, Subramanian, Panchu, Ndeleva, Benjamin Muluku, Lutomia, Mark, Otseyeno, Fred Mathew Toboso, Mwangi, Geoffrey Chege, Ndasi, Henry Tanyi, Konadu-Yeboah, Dominic, Firth, Gregory, Marealle, Paul, Temu, Rogers, Mutanda, Tony, Rio, Marcelo, Quintero, Jose Eduardo, Zuluaga, Mauricio, Minueza, Tomás, Madrigal, Ricardo, Ylizaliturri, Manuel, Garuz, Mario, Segovia Altieri, Julio, Escalante Elguezabal, Igor A., Armstrong, Elizabeth, Rogers, Kris, Li, Chuan Silvia, Jagnoor, Jagnoor, Moroz, Paul, Oguzie, Gerald Chukwuemeka, Hailu, Samuel, Miclau, Theodore, III, de la Huerta, Fernando, Martinez-Ruiz, Jose de Jesus, Bidolegui, Fernando, Zhou, Junlin, Ma, Xinlong, Wu, Bo, Sancheti, Parag, Quang, La Ngoc, Baigi, Vali, Haddadi, Mashyaneh, Tian, Maoyi, Sprague, Sheila, Devereaux, P J, Bhandari, Mohit, and Ivers, Rebecca

Published
2024
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9. A community-based intervention to improve screening, referral and follow-up of non-communicable diseases and anaemia amongst pregnant and postpartum women in rural India: study protocol for a cluster randomised trial

Author

Hirst, Jane Elizabeth, Votruba, Nicole, Billot, Laurent, Arora, Varun, Rajan, Eldho, Thout, Sudhir Raj, Peiris, David, Patel, Anushka, Norton, Robyn, Mullins, Edward, Sharma, Ankita, Kennedy, Stephen, Jha, Vivekanand, and Praveen, Devarsetty

Published
2023
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24. Protocol for process evaluation of ARTEMIS cluster randomised controlled trial: an intervention for management of depression and suicide among adolescents living in slums in India

Author

Mukherjee, Ankita, primary, Yatirajula, Sandhya Kanaka, additional, Kallakuri, Sudha, additional, Paslawar, Srilatha, additional, Lempp, Heidi, additional, Raman, Usha, additional, Kumar, Ashok, additional, Essue, Beverley M, additional, Sagar, Rajesh, additional, Singh, Renu, additional, Peiris, David, additional, Norton, Robyn, additional, Thornicroft, Graham, additional, and Maulik, Pallab Kumar, additional

Published
2024
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26. An intervention to reduce stigma and improve management of depression, risk of suicide/self-harm and other significant emotional or medically unexplained complaints among adolescents living in urban slums: protocol for the ARTEMIS project

Author

Yatirajula, Sandhya Kanaka, Kallakuri, Sudha, Paslawar, Srilatha, Mukherjee, Ankita, Bhattacharya, Amritendu, Chatterjee, Susmita, Sagar, Rajesh, Kumar, Ashok, Lempp, Heidi, Raman, Usha, Singh, Renu, Essue, Beverley, Billot, Laurent, Peiris, David, Norton, Robyn, Thornicroft, Graham, and Maulik, Pallab K.

Published
2022
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28. Why does a public health issue (not) get priority? Agenda setting for the national burns programme in India.

Author

Keshri, Vikash Ranjan, Jagnoor, Jagnoor, Peden, Margie, Norton, Robyn, and Abimbola, Seye

Subjects
PUBLIC health, CAPITAL cities, FRAMES (Social sciences), THEMATIC analysis
Abstract

There is growing scholarly interest in what leads to global or national prioritization of specific health issues. By retrospectively analysing agenda setting for India's national burn programme, this study aimed to better understand how the agenda-setting process influenced its design, implementation and performance. We conducted document reviews and key informant interviews with stakeholders and used a combination of analytical frameworks on policy prioritization and issue framing for analysis. The READ (readying material, extracting data, analysing data and distilling findings) approach was used for document reviews, and qualitative thematic analysis was used for coding and analysis of documents and interviews. The findings suggest three critical features of burns care policy prioritization in India: challenges of issue characteristics, divergent portrayal of ideas and its framing as a social and/or health issue and over-centralization of agenda setting. First, lack of credible indicators on the magnitude of the problem and evidence on interventions limited issue framing, advocacy and agenda setting. Second, the policy response to burns has two dimensions in India: response to gender-based intentional injuries and the healthcare response. While intentional burns have received policy attention, the healthcare response was limited until the national programme was initiated in 2010 and scaled up in 2014. Third, over-centralization of agenda setting (dominated by a few homogenous actors, located in the national capital, with attention focused on the national ministry of health) contributed to limitations in programme design and implementation. We note following elements to consider when analysing issues of significant burden but limited priority: the need to analyse how actors influence issue framing, the particularities of issues, the inadequacy of any one dominant frame and the limited intersection of frames. Based on this analysis in India, we recommend a decentralized approach to agenda setting and for the design and implementation of national programmes from the outset. [ABSTRACT FROM AUTHOR]

Published
2024
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29. Delays in hospital admissions in patients with fractures across 18 low-income and middle-income countries (INORMUS): a prospective observational study

Author

Bhandari, Mohit, Devereaux, PJ, Guyatt, Gordon, Petrisor, Brad, Thabane, Lehana, Boniface, Respicious L., Browner, Bruce, de la Huerta, Fernando, Ivers, Rebecca Q, Miclau, Theodore, III, Moroz, Paul, Pollak, Andrew, Slobogean, Gerard, Sancheti, Parag, Schemitsch, Emil, Zhou, Junlin, Sprague, Sheila, McKay, Paula, Li, Chuan Silvia, Mundi, Raman, O'Hara, Nathan, Heels-Ansdell, Diane, Buckingham, Lisa, Simunovic, Nicole, Jagnoor, Jagnoor, Norton, Robyn, Zhang, Jing, Tian, Maoyi, Bhaumik, Soumyadeep, Parveen, Samina, Morshed, Saam, MacKechnie, Madeline C., Liu, Yang, Zhao, Yanrui, Li, Junfei, Zhang, Haoran, Zhang, Zhentao, Zhang, Wei, Guo, Tao, Chen, Guang, Jia, Zichao, Yang, Jianzhong, Kang, Lixing, Zhang, Peng, Ma, Haoqing, Liu, Donghai, Ma, Yinghua, Qin, Yanguo, Wang, Jincheng, Liu, He, Ma, Xinlong, Ma, Jianxiong, Jia, Haobo, Cui, Shuangshuang, Zhao, Zhihu, Fu, Lin, Jiang, Hongqiang, Lv, Jianwei, Hu, Sanbao, Wang, Yongwei, Sun, Mingyao, Tao, Shuqing, Qi, Baochang, Gao, Ming, Wu, Bo, Zhi, Chunsheng, Xing, Ben, Yang, Jun, Dai, Wenjie, Lu, Duo, He, Shisheng, Cai, Xinyu, Liu, Gejun, Rui, Gang, Hu, Baoshan, Shi, Pingfang, Chen, Hua, Wang, Te, Wang, Qingqing, Xie, Linzhen, Xie, Huanguang, Mutanda, Tony, Ntuulo, Juliet, Lubega, Flavia, Tracy, Gayita Teddy, Zaitun, Kayondo, Ndayisaba, Sylvester, Amone, Titus, Odong, Samuel Remmy, Lutomia, Mark, Okatch, Caesar, Bitok, Thomas, Kiambuthi, Alexander, Otsyeno, Fred Mathew Toboso, Jani, Pankaj G, Mutiso, Vincent Muoki, Ating'a, John EO, Kilonzo, Peter Kavoo, Muoki, James, Mbogori, Makena, Wambugu, Joan Wambui, Torutt, Dorothy, Odok, Christopher, Ngetich, Elisha, Otsyeno, Dean, Wakhayanga, Juma, Nzioka, Desmond, Owende, Deogracia, Lucinde, Ruth, Kariuki, Brian Ngure, Kinyua, Dennis, Kamau, Maureen, Mwancha, Maureen, Murgor, Mellany, Nyabuti, Marilyn, Njoki, Rita, Wanza, Patricia, Odongo, Abraham, Marealle, Paul, Wanini, Athman, Elisha, Marwa, Zumbulu, Damas, Godfrey, Pariyo Bonane, Ndeleva, Benjamin Mukulu, Johnson, Murila, Kimani, Moses, Gichui, Kinuthia, Temu, Rogers Joachin, Mselle, Angela Neofitus, Kimario, Ancelimu Rafael, Ramokgopa, Mmampapatla Thomas, Firth, Gregory, Biscardi, Anna Grisillo, Poopedi, Machuene Ananias, Moolman, Johan, Milner, Brenda, Maluleke, Matimba, Jingo, Maxwell, van Deventer, Susan, Pikor, Timothy, Bhaga, Ravi, Mara, Michael, Mwangi, Geoffrey Chege, Maina, Anthony Muchiri, Gicheru, David Wamae, Mwangi, Carol, Wangai, Isaac Kingori, Maina, Peter Watson, Kiptoo, Ezra Mitei, Temiloluwa, Olufemi Olukemi, Ikechukwu, Adeyeye Adeolu, Olugbenga, Ige Oluwole, Bamidele, Ojodu Ishaq, Akanbi, Oladimeji Oladipupo, Subramanian, Panchu, Mosweu, Olivia L, Hailu, Samuel, Tessema, Geletaw, Bezabih, Bahiru, Ayana, Birhanu, Hailu, Hiwot, Zewdneh, Betelhem, Tesfaye, Hana, Tadesse, Sosena, Konadu-Yeboah, Dominic, Ativor, Vincent, Konadu, Peter, Awariyah, Dominic, Quartey, Raphael, Kumah-Ametepey, Raphael, Saani, Osman, Quansah, Robert Ekow, Baidoo, Paa Kwesi, Trafton, Peter, Anyitey-Korkor, David, Leat, Michael, Sobotie, Johnny, Opuni, Godwin, Kusi, Kwasi, Baah, Twimasi, Okyere, Paul, Mensah, Bernice, Sarpong, Doris Akuoko, Agbenorwu, Felicia, Osei-Donkor, Phyllis, Opoku, Priscilla, Segbefia, Michael, Oguzie, Gerald Chukwuemeka, Iyidobi, Emmanuel Chino, Nwadinigwe, Cajetan Uwatoronye, Oguzie, Sharon Amarachi Uloma, Kesiena, Emina Bami, Ndasi, Henry Tanyi, Ghislain, Nietiayurk Aminake, Shey, Mala Irine, Nanje, Ikose John, Shyam, Ashok, Borate, Madhav, Patil, Sampat Dumbre, Karkamakar, Sachin, Patil, Shailesh, Ranaware, Abhijeet, Tamboli, Shadab, Gandhalikar, Manish, Tupe, Rohini, Chaudhari, Vishal, Joshi, Avanti, Patil, Sanjay, Dalwekar, Mohit Madhukar, Gandhi, Tejas, Latkar, Chintamani, Pundkare, Gopal, Shrivastava, Sandeep, Singh, Pradeep K, Deshpande, Sanjay, Baheti, Sumit, Mittal, Ravi, Sharma, Vijay, Cherian, Vinoo Mathew, Jepegnanam, Thilak Samuel, Titus, Vijay T K, Nithyananth, Manasseh, Boopalan, Palapattu R J V C, Varghese, Viju Daniel, Arockiaraj, Justin, Mahajan, Anupam, John, Bobby, Pandey, Ritesh, Prakash, Jeewan S, Abraham, Valsamma, Rajkumar, Arti, Chhabra, Harvinder Singh, Sharawat, Rajesh, Kumar, Ritabh, Chawla, Pushkar, Yadav, Rashmi, Iyer, Rajagopalan N, Nair, Naveen, Amaravathi, Rajkumar S, Santhanagopa, Srinivasalu, Pilar, Anoop, Tamboowala, Keith Behram, Dhillon, Mandeep S, Dhatt, Sarvdeep S, Chase, Asolie, Bhavsar, Neel M, Musa, Rameez, Shah, Darshan, Chodavadiyah, Sunil, Patel, Pankaj G, Qadir, Raja Irfan, Bukhari, Syed Imran, Baz, Khushnood Ali, Byanjankar, Subin, Joshi, Ruban Raj, Dwivedi, Rajeev, Sharma, Jay Raj, Quang, La Ngoc, Chinh, Nguyen Duc, Hong, Vu Bao, Sa-ngasoongsong, Paphon, Kulachote, Noratep, Sirisreetreerux, Norachart, Pongsamakthai, Wanjak, Tabu, Irewin Alagar, Reyes, Paula Veronica, Caiquep, Iardinne, Bituin, Joni Mitchell Robles, González, Jenna, Golbakhsh, Mohammadreza, Haddadi, Mashyaneh, Saadat, Soheil, Zafarghandi, Mohammadreza, Orozco, Clotilde Fuentes, Ruíz, José de Jesús Martínez, Arreguin, Gustavo Armando Tafoya, Flores, César Eduardo Pinedo, Verduzco, Irydia Guadalupe Pellegrini, Camacho, Miguel Oscar Hernandez, Téllez, Diego Abraham Estrada, López, Rodrigo Salcedo, Navarro, Ileana Guadalupe Canales, Pérez, Mizael Dennis, Carrillo, Daniel de Jesús Enciso, López, Paola Alejandra Álvarez, Gómez, Adán Cervantes, Bravo, Fátima Nohemí Franco, Arias, Eugenia de los Ángeles Reyes, Elguezabal, Igor A. Escalante, Rizzo, Ennio Antonio, Hovsepian, Jean Michel, Rodriguez, Victor, Baldo, Manuel Malaret, Serrano, Andres, Valenciano, Carlos G. Sanchez, Salcedo, Edgar Efren Mercado, Medina, Fryda, Bidolegui, Fernando, Pereira, Sebastian, Aguilar, Gerardo, Rubio-Avila, Jorge, Belangero, William Dias, Mariolani, José Ricardo Lenzi, Livani, Bruno, Lugnani, André, Rossi, Felipe, Katayama, Angela, Baldy, Fernando, de Moraes, Vinícius Ynoe, Fogagnolo, Fabricio, Kojima, Kodi Edson, Silva, Jorge dos Santos, Demange, Marco Kawamura, de Andrade-Silva, Fernando Brandão, da Silva, Adriana Carvalho Gomes, Elias, Nelson, Martinez, Dino Aguilar, Contreras, Fernando, Garuz, Mario, Quintero, Jose Eduardo, Merchan, Gavino, Lurita, Christian M. Lozano, Manrique, Aturo D. Torres, Fernandez, Jorge Hurtado, Vincenti, Sergio Iriarte, Bobarin, Alfredo Pozzo, Sanchez, Dalton Salinas, Altieri, Julio Segovia, Almada, Diego, Bogado, Derlis, Coronel, Carlos, Boveda, Cristian, del Valle, Victor, Montiel, Carlos, Marin, Nelson, Barquet, Antonio, Rienzi, Daniel, Amanquez, Carlos, Beauvoir, Georges, Cutipa, Iván J Salce, Ribeiro, José Eduardo Grandi, Avila, José María Jiménez, Padilla, Luis, Ochoa, Hernando Cuevas, Cano, Hernando Cuevas, González, Adriana Vaca, Gutierrez, Nubia Itzel Gonzalez, Espinola, Victor, Pouramin, Panthea, Busse, Jason W, Devereaux, P J, and Ivers, Rebecca

Published
2020
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32. A Mobile Clinical Decision Support System for High-Risk Pregnant Women in Rural India (SMARThealth Pregnancy): Pilot Cluster Randomized Controlled Trial

Author

Nagraj, Shobhana, primary, Kennedy, Stephen, additional, Jha, Vivekananda, additional, Norton, Robyn, additional, Hinton, Lisa, additional, Billot, Laurent, additional, Rajan, Eldho, additional, Mohammed Abdul, Ameer, additional, Phalswal, Anita, additional, Arora, Varun, additional, Praveen, Devarsetty, additional, and Hirst, Jane, additional

Published
2023
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33. Burden of non-communicable diseases and behavioural risk factors in Mexico: Trends and gender observational analysis

Author

Guerrero-López, Carlos M, primary, Serván-Mori, Edson, additional, Miranda, J Jaime, additional, Jan, Stephen, additional, Orozco-Núñez, Emanuel, additional, Downey, Laura, additional, Feeny, Emma, additional, Heredia-Pi, Ileana, additional, Flamand, Laura, additional, Nigenda, Gustavo, additional, and Norton, Robyn, additional

Published
2023
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34. Multi-morbidity and blood pressure trajectories in hypertensive patients: A multiple landmark cohort study

Author

Tran, Jenny, Norton, Robyn, Canoy, Dexter, Ayala Solares, Jose Roberto, Conrad, Nathalie, Nazarzadeh, Milad, Raimondi, Francesca, Salimi-Khorshidi, Gholamreza, Rodgers, Anthony, and Rahimi, Kazem

Subjects
Blood pressure -- Demographic aspects, Comorbidity -- Physiological aspects -- Care and treatment, Hypertension -- Care and treatment, Biological sciences
Abstract

Background Our knowledge of how to better manage elevated blood pressure (BP) in the presence of comorbidities is limited, in part due to exclusion or underrepresentation of patients with multiple chronic conditions from major clinical trials. We aimed to investigate the burden and types of comorbidities in patients with hypertension and to assess how such comorbidities and other variables affect BP levels over time. Methods and findings In this multiple landmark cohort study, we used linked electronic health records from the United Kingdom Clinical Practice Research Datalink (CPRD) to compare systolic blood pressure (SBP) levels in 295,487 patients (51% women) aged 61.5 (SD = 13.1) years with first recorded diagnosis of hypertension between 2000 and 2014, by type and numbers of major comorbidities, from at least 5 years before and up to 10 years after hypertension diagnosis. Time-updated multivariable linear regression analyses showed that the presence of more comorbidities was associated with lower SBP during follow-up. In hypertensive patients without comorbidities, mean SBP at diagnosis and at 10 years were 162.3 mm Hg (95% confidence interval [CI] 162.0 to 162.6) and 140.5 mm Hg (95% CI 140.4 to 140.6), respectively; in hypertensive patients with [greater than or equal to]5 comorbidities, these were 157.3 mm Hg (95% CI 156.9 to 157.6) and 136.8 mm Hg (95% 136.4 to 137.3), respectively. This inverse association between numbers of comorbidities and SBP was not specific to particular types of comorbidities, although associations were stronger in those with preexisting cardiovascular disease. Retrospective analysis of recorded SBP showed that the difference in mean SBP 5 years before diagnosis between those without and with [greater than or equal to]5 comorbidities was -9 mm Hg (95% CI -9.7 to -8.3), suggesting that mean recorded SBP already differed according to the presence of comorbidity before baseline. Within 1 year after the diagnosis, SBP substantially declined, but subsequent SBP changes across comorbidity status were modest, with no evidence of a more rapid decline in those with more or specific types of comorbidities. We identified factors, such as prescriptions of antihypertensive drugs and frequency of healthcare visits, that can explain SBP differences according to numbers or types of comorbidities, but these factors only partly explained the recorded SBP differences. Nevertheless, some limitations have to be considered including the possibility that diagnosis of some conditions may not have been recorded, varying degrees of missing data inherent in analytical datasets extracted from routine health records, and greater measurement errors in clinical measurements taken in routine practices than those taken in well-controlled clinical study settings. Conclusions BP levels at which patients were diagnosed with hypertension varied substantially according to the presence of comorbidities and were lowest in patients with multi-morbidity. Our findings suggest that this early selection bias of hypertension diagnosis at different BP levels was a key determinant of long-term differences in BP by comorbidity status. The lack of a more rapid decline in SBP in those with multi-morbidity provides some reassurance for BP treatment in these high-risk individuals., Author(s): Jenny Tran 1, Robyn Norton 2, Dexter Canoy 1,3,4,5, Jose Roberto Ayala Solares 1, Nathalie Conrad 1, Milad Nazarzadeh 1,3, Francesca Raimondi 1, Gholamreza Salimi-Khorshidi 1,3, Anthony Rodgers 2, [...]

Published
2021
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35. A Gender-Based and Quasi-Experimental Study of the Catastrophic and Impoverishing Health-Care Expenditures in Mexican Households with Elderly Members, 2000-2020

Author

Serván-Mori, Edson, primary, Orozco-Núñez, Emanuel, additional, Guerrero-López, Carlos M., additional, Miranda, J. Jaime, additional, Jan, Stephen, additional, Downey, Laura, additional, Feeny, Emma, additional, Heredia-Pi, Ileana, additional, Flamand, Laura, additional, Nigenda, Gustavo, additional, Norton, Robyn, additional, and Lozano, Rafael, additional

Published
2023
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39. Additional file 1 of An intervention to reduce stigma and improve management of depression, risk of suicide/self-harm and other significant emotional or medically unexplained complaints among adolescents living in urban slums: protocol for the ARTEMIS project

Author

Yatirajula, Sandhya Kanaka, Kallakuri, Sudha, Paslawar, Srilatha, Mukherjee, Ankita, Bhattacharya, Amritendu, Chatterjee, Susmita, Sagar, Rajesh, Kumar, Ashok, Lempp, Heidi, Raman, Usha, Singh, Renu, Essue, Beverley, Billot, Laurent, Peiris, David, Norton, Robyn, Thornicroft, Graham, and Maulik, Pallab K.

Abstract

Additional file 1: Participant Information Sheet for Adults (parents/guardians/ASHAs/Doctors/Other stakeholders) /Adolescents in the community (Baseline/Intervention/ Post trial).

Published
2022
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47. Patterns and temporal trends of comorbidity among adult patients with incident cardiovascular disease in the UK between 2000 and 2014: A population-based cohort study

Author

Tran, Jenny, Norton, Robyn, Conrad, Nathalie, Rahimian, Fatemeh, Canoy, Dexter, Nazarzadeh, Milad, and Rahimi, Kazem

Subjects
Comorbidity -- Forecasts and trends -- Patient outcomes -- Risk factors, Cardiovascular diseases -- Patient outcomes -- Complications and side effects, Adults -- Health aspects, Market trend/market analysis, Biological sciences
Abstract

Background Multimorbidity in people with cardiovascular disease (CVD) is common, but large-scale contemporary reports of patterns and trends in patients with incident CVD are limited. We investigated the burden of comorbidities in patients with incident CVD, how it changed between 2000 and 2014, and how it varied by age, sex, and socioeconomic status (SES). Methods and findings We used the UK Clinical Practice Research Datalink with linkage to Hospital Episode Statistics, a population-based dataset from 674 UK general practices covering approximately 7% of the current UK population. We estimated crude and age/sex-standardised (to the 2013 European Standard Population) prevalence and 95% confidence intervals for 56 major comorbidities in individuals with incident non-fatal CVD. We further assessed temporal trends and patterns by age, sex, and SES groups, between 2000 and 2014. Among a total of 4,198,039 people aged 16 to 113 years, 229,205 incident cases of non-fatal CVD, defined as first diagnosis of ischaemic heart disease, stroke, or transient ischaemic attack, were identified. Although the age/sex-standardised incidence of CVD decreased by 34% between 2000 to 2014, the proportion of CVD patients with higher numbers of comorbidities increased. The prevalence of having 5 or more comorbidities increased 4-fold, rising from 6.3% (95% CI 5.6%-17.0%) in 2000 to 24.3% (22.1%-34.8%) in 2014 in age/sex-standardised models. The most common comorbidities in age/sex-standardised models were hypertension (28.9% [95% CI 27.7%-31.4%]), depression (23.0% [21.3%-26.0%]), arthritis (20.9% [19.5%-23.5%]), asthma (17.7% [15.8%-20.8%]), and anxiety (15.0% [13.7%-17.6%]). Cardiometabolic conditions and arthritis were highly prevalent among patients aged over 40 years, and mental illnesses were highly prevalent in patients aged 30-59 years. The age-standardised prevalence of having 5 or more comorbidities was 19.1% (95% CI 17.2%-22.7%) in women and 12.5% (12.0%-13.9%) in men, and women had twice the age-standardised prevalence of depression (31.1% [28.3%-35.5%] versus 15.0% [14.3%-16.5%]) and anxiety (19.6% [17.6%-23.3%] versus 10.4% [9.8%-11.8%]). The prevalence of depression was 46% higher in the most deprived fifth of SES compared with the least deprived fifth (age/sex-standardised prevalence of 38.4% [31.2%-62.0%] versus 26.3% [23.1%-34.5%], respectively). This is a descriptive study of routine electronic health records in the UK, which might underestimate the true prevalence of diseases. Conclusions The burden of multimorbidity and comorbidity in patients with incident non-fatal CVD increased between 2000 and 2014. On average, older patients, women, and socioeconomically deprived groups had higher numbers of comorbidities, but the type of comorbidities varied by age and sex. Cardiometabolic conditions contributed substantially to the burden, but 4 out of the 10 top comorbidities were non-cardiometabolic. The current single-disease paradigm in CVD management needs to broaden and incorporate the large and increasing burden of comorbidities., Author(s): Jenny Tran 1,2, Robyn Norton 1,3, Nathalie Conrad 1, Fatemeh Rahimian 1,2, Dexter Canoy 1,2, Milad Nazarzadeh 1,4, Kazem Rahimi 1,2,5,* Introduction Comorbidities, defined as the presence of additional [...]

Published
2018
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48. SMARThealth Pregnancy: Feasibility and Acceptability of a Complex Intervention for High-Risk Pregnant Women in Rural India: Protocol for a Pilot Cluster Randomised Controlled Trial

Author

Nagraj, Shobhana, primary, Kennedy, Stephen H., additional, Jha, Vivekananda, additional, Norton, Robyn, additional, Hinton, Lisa, additional, Billot, Laurent, additional, Rajan, Eldho, additional, Arora, Varun, additional, Praveen, Devarsetty, additional, and Hirst, Jane E., additional

Published
2021
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50. Investigating sex differences in the accuracy of dietary assessment methods to measure energy intake in adults: a systematic review and meta-analysis

Author

McKenzie, Briar L, primary, Coyle, Daisy H, additional, Santos, Joseph Alvin, additional, Burrows, Tracy, additional, Rosewarne, Emalie, additional, Peters, Sanne AE, additional, Carcel, Cheryl, additional, Jaacks, Lindsay M, additional, Norton, Robyn, additional, Collins, Clare E, additional, Woodward, Mark, additional, and Webster, Jacqui, additional

Published
2021
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