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10. Early and late improvement of global and regional left ventricular function after transcatheter aortic valve implantation in patients with severe aortic stenosis: an echocardiographic study

Author

Giannini, Cristina, Petronio, Anna Sonia, Talini, Enrica, Marco De Carlo, Guarracino, Fabio, Grazia, Maria, Donne, Delle, Nardi, Carmela, Conte, Lorenzo, Barletta, Valentina, Marzilli, Mario, and Di Bello, Vitantonio

Subjects
Transcatheter aortic valve implantation, left ventricular function, 2D strain, Original Article
Abstract

The recent development of transcatheter aortic valve implantation (TAVI) for severe aortic stenosis (AS) treatment offers a viable option for high-risk patient categories. Our aim is to evaluate whether 2D strain and strain rate can detect subtle improvement in global and regional LV systolic function immediately after TAVI. 2D conventional and 2D strain (speckle analysis) echocardiography was performed before, at discharge and after three months in thirty three patients with severe AS. After TAVI, we assessed by conventional echocardiography an immediate reduction of transaortic peak pressure gradient (p

Published
2011

11. COMPARISON OF THE HEMOYNAMIC PERFORMANCE AND LEFT VENTRICULAR REMODELING OF PERCUTANEOUS VS SURGICAL BIOPROSTHESES IN TREATMENT OF SEVERE AORTIC STENOSIS

Author

Giannini, Cristina, primary, De Carlo, Marco, additional, Guarracino, Fabio, additional, Talini, Enrica, additional, Donne, Maria Grazia Delle, additional, Nardi, Carmela, additional, Dini, Frank Llojd, additional, Bortolotti, Uberto, additional, Minzioni, Gaetano, additional, Petronio, Anna Sonia, additional, and Di Bello, Vitantonio, additional

Published
2010
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12. Severe Aortic Stenosis and Myocardial Function

Author

Bello, Vitantonio Di, primary, Giorgi, Davide, additional, Viacava, Paolo, additional, Enrica, Talini, additional, Nardi, Carmela, additional, Palagi, Caterina, additional, Donne, Maria Grazia Delle, additional, Verunelli, Francesco, additional, Mariani, Massimo A., additional, Grandjean, Jean, additional, Dell’Anna, Rita, additional, Di Cori, Andrea, additional, Zucchelli, Giulio, additional, Romano, Maria Francesca, additional, and Mariani, Mario, additional

Published
2004
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13. Surgical implantation of bone marrow cells may reverse perfusion and wall motion abnormalities in patients with previous myocardial infarction and dominance of scar

Author

Mariani, Massimo, primary, Limbruno, Ugo, additional, Favre, Claudio, additional, Marzullo, Paolo, additional, Sambuceti, Gianmario, additional, Di Bello, Vitoantonio, additional, Giorgi, Davide, additional, Di Stefano, Rossella, additional, Nardi, Carmela, additional, Petronio, Anna S., additional, Dell'Anna, Rita, additional, Grandjean, Jean, additional, and Mariani, Mario, additional

Published
2003
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19. Early and late improvement of global and regional left ventricular function after transcatheter aortic valve implantation in patients with severe aortic stenosis: an echocardiographic study.

Author

Giannini C, Petronio AS, Talini E, De Carlo M, Guarracino F, Grazia M, Donne D, Nardi C, Conte L, Barletta V, Marzilli M, and Di Bello V

Abstract

The recent development of transcatheter aortic valve implantation (TAVI) for severe aortic stenosis (AS) treatment offers a viable option for high-risk patient categories. Our aim is to evaluate whether 2D strain and strain rate can detect subtle improvement in global and regional LV systolic function immediately after TAVI. 2D conventional and 2D strain (speckle analysis) echocardiography was performed before, at discharge and after three months in thirty three patients with severe AS. After TAVI, we assessed by conventional echocardiography an immediate reduction of transaortic peak pressure gradient (p<0.0001), of mean pressure gradient (p<0.0001) and a concomitant increase in aortic valve area (AVA: 1.08±0.31 cm(2)/m(2); p<0.0001). 2D longitudinal systolic strain showed a significant improvement in all patients, both at septal and lateral level, as early as 72 h after procedure (septal: -14.2±5.1 vs -16.7±3.7%, p<0.001; lateral: -9.4±3.9 vs -13.1±4.5%, p<0.001; respectively) and continued at 3 months follow-up (septal: -18.1±4.6%, p<0.0001; lateral: -14.8±4.4%, p<0.0001; respectively). Conventional echocardiography after TAVI proved a significant reduction of LV end-systolic volume and of LV mass with a mild improvement of LV ejection fraction (EF) (51.2±11.8 vs 52.9±6.4%; p<0.02) only after three months. 2D strain seems to be able to detect subtle changes in LV systolic function occurring early and late after TAVI in severe AS, while all conventional echo parameters seem to be less effective for this purpose. Further investigations are needed to prove the real prognostic impact of these echocardiographic findings.

Published
2011

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