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4 results on '"Nakai, Isako"'

1. <Originals> Sudden Death and its Circumstances : 20-Year Retrospective Study of Newspaper Accounts

Author

Kambara, Hirofumi, Nakai, Isako, and Yasuda, Kayo

Abstract

The circumstances surrounding sudden death (SD) and its cause as reported in newspaper articles between 1970 and 1989 are retrospectively studied. In total, 223 cases of SD were reported. In children, sudden infant death syndrome was the most frequent cause of SD. In young adults SD was frequently encountered during exercise, while in the middle age at rest. SD was five times more common in males than in females, and approximately 70% of SD was due to cardiovascular diseases usually with fatal outcome within one hour after onset of symptoms. Thus, in order to prevent SD it is of utmost importance to educate the public to start cardiopulmonary resuscitation at sight as well as to have regular medical checkups to rule out latent cardiovascular diseases.

Published
1991

2. Laboratory Surveillance for Prospective Plasmid-Mediated AmpC β-Lactamases in the Kinki Region of Japan

Author

Yamasaki, Katsutoshi, primary, Komatsu, Masaru, additional, Abe, Noriyuki, additional, Fukuda, Saori, additional, Miyamoto, Yugo, additional, Higuchi, Takeshi, additional, Ono, Tamotsu, additional, Nishio, Hisaaki, additional, Sueyoshi, Noriyuki, additional, Kida, Kaneyuki, additional, Satoh, Kaori, additional, Toyokawa, Masahiro, additional, Nishi, Isao, additional, Sakamoto, Masako, additional, Akagi, Masahiro, additional, Nakai, Isako, additional, Kofuku, Tomomi, additional, Orita, Tamaki, additional, Wada, Yasunao, additional, Jikimoto, Takumi, additional, Kinoshita, Shohiro, additional, Miyamoto, Kazuaki, additional, Hirai, Itaru, additional, and Yamamoto, Yoshimasa, additional

Published
2010
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3. Laboratory Surveillance for Prospective Plasmid-Mediated AmpC ß-Lactamases in the Kinki Region of Japan

Author

Yamasaki, Katsutoshi, Komatsu, Masaru, Abe, Noriyuki, Fukuda, Saori, Miyamoto, Yugo, Higuchi, Takeshi, Ono, Tamotsu, Nishio, Hisaaki, Sueyoshi, Noriyuki, Kida, Kaneyuki, Satoh, Kaori, Toyokawa, Masahiro, Nishi, Isao, Sakamoto, Masako, Akagi, Masahiro, Nakai, Isako, Kofuku, Tomomi, Orita, Tamaki, Wada, Yasunao, Jikimoto, Takumi, Kinoshita, Shohiro, Miyamoto, Kazuaki, Hirai, Itaru, and Yamamoto, Yoshimasa

Abstract

ABSTRACTExtended-spectrum ß-lactamases, plasmid-mediated AmpC ß-lactamases (PABLs), and plasmid-mediated metallo-ß-lactamases confer resistance to many ß-lactams. In Japan, although several reports exist on the prevalence of extended-spectrum ß-lactamases and metallo-ß-lactamases, the prevalence and characteristics of PABLs remain unknown. To investigate the production of PABLs, a total of 22,869 strains of 4 enterobacterial species, Escherichia coli, Klebsiella pneumoniae, Klebsiella oxytoca, and Proteus mirabilis, were collected during six 6-month periods from 17 clinical laboratories in the Kinki region of Japan. PABLs were detected in 29 (0.13%) of 22,869 isolates by the 3-dimensional test, PCR analysis, and DNA sequencing analysis. PABL-positive isolates were detected among isolates from 13 laboratories. Seventeen of 13,995 (0.12%) E. coliisolates, 8 of 5,970 (0.13%) K. pneumoniaeisolates, 3 of 1,722 (0.17%) K. oxytocaisolates, and 1 of 1,182 (0.08%) P. mirabilisisolates were positive for PABLs. Of these 29 PABL-positive strains, 20 (69.0%), 6 (20.7%), 2 (6.9%), and 1 (3.4%) carried the genes for CMY-2, DHA-1, CMY-8, and MOX-1 PABLs, respectively. Pattern analysis of randomly amplified polymorphic DNA and pulsed-field gel electrophoretic analysis revealed that the prevalence of CMY-2-producing E. colistrains was not due to epidemic strains and that 3 DHA-1-producing K. pneumoniaestrains were identical, suggesting their clonal relatedness. In conclusion, the DHA-1 PABLs were predominantly present in K. pneumoniaestrains, but CMY-2 PABLs were predominantly present in E. colistrains. The present findings will provide significant information to assist in preventing the emergence and further spread of PABL-producing bacteria.

Published
2010
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4. Laboratory surveillance for prospective plasmid-mediated AmpC beta-lactamases in the Kinki region of Japan.

Author

Yamasaki K, Komatsu M, Abe N, Fukuda S, Miyamoto Y, Higuchi T, Ono T, Nishio H, Sueyoshi N, Kida K, Satoh K, Toyokawa M, Nishi I, Sakamoto M, Akagi M, Nakai I, Kofuku T, Orita T, Wada Y, Jikimoto T, Kinoshita S, Miyamoto K, Hirai I, and Yamamoto Y

Subjects
Anti-Bacterial Agents pharmacology, Bacterial Typing Techniques, DNA Fingerprinting, DNA, Bacterial chemistry, DNA, Bacterial genetics, Electrophoresis, Gel, Pulsed-Field, Escherichia coli drug effects, Escherichia coli genetics, Escherichia coli isolation & purification, Humans, Japan, Klebsiella drug effects, Klebsiella genetics, Klebsiella isolation & purification, Microbial Sensitivity Tests, Molecular Epidemiology, Polymerase Chain Reaction, Proteus mirabilis drug effects, Proteus mirabilis genetics, Proteus mirabilis isolation & purification, Random Amplified Polymorphic DNA Technique, Sequence Analysis, DNA, beta-Lactams pharmacology, Bacterial Proteins biosynthesis, Bacterial Proteins genetics, Enterobacteriaceae Infections microbiology, Escherichia coli enzymology, Klebsiella enzymology, Plasmids analysis, Proteus mirabilis enzymology, beta-Lactamases biosynthesis, beta-Lactamases genetics
Abstract

Extended-spectrum beta-lactamases, plasmid-mediated AmpC beta-lactamases (PABLs), and plasmid-mediated metallo-beta-lactamases confer resistance to many beta-lactams. In Japan, although several reports exist on the prevalence of extended-spectrum beta-lactamases and metallo-beta-lactamases, the prevalence and characteristics of PABLs remain unknown. To investigate the production of PABLs, a total of 22,869 strains of 4 enterobacterial species, Escherichia coli, Klebsiella pneumoniae, Klebsiella oxytoca, and Proteus mirabilis, were collected during six 6-month periods from 17 clinical laboratories in the Kinki region of Japan. PABLs were detected in 29 (0.13%) of 22,869 isolates by the 3-dimensional test, PCR analysis, and DNA sequencing analysis. PABL-positive isolates were detected among isolates from 13 laboratories. Seventeen of 13,995 (0.12%) E. coli isolates, 8 of 5,970 (0.13%) K. pneumoniae isolates, 3 of 1,722 (0.17%) K. oxytoca isolates, and 1 of 1,182 (0.08%) P. mirabilis isolates were positive for PABLs. Of these 29 PABL-positive strains, 20 (69.0%), 6 (20.7%), 2 (6.9%), and 1 (3.4%) carried the genes for CMY-2, DHA-1, CMY-8, and MOX-1 PABLs, respectively. Pattern analysis of randomly amplified polymorphic DNA and pulsed-field gel electrophoretic analysis revealed that the prevalence of CMY-2-producing E. coli strains was not due to epidemic strains and that 3 DHA-1-producing K. pneumoniae strains were identical, suggesting their clonal relatedness. In conclusion, the DHA-1 PABLs were predominantly present in K. pneumoniae strains, but CMY-2 PABLs were predominantly present in E. coli strains. The present findings will provide significant information to assist in preventing the emergence and further spread of PABL-producing bacteria.

Published
2010
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