1. A Case Report of Successful Kidney Donation After Brain Death Following Nicotine Intoxication
- Author
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J. Kalliomaki, Ilkka Helanterä, Marko Lempinen, M. Rasanen, Mikko J. Parry, Johanna Savikko, Clinicum, IV kirurgian klinikka, Department of Surgery, Transplantation Laboratory, Medicum, HUS Heart and Lung Center, and HUS Abdominal Center
- Subjects
Adult ,Brain Death ,Nicotine ,Tissue and Organ Procurement ,Encephalopathy ,Respiratory arrest ,030204 cardiovascular system & hematology ,Electronic Nicotine Delivery Systems ,Kidney ,Nephrectomy ,Donor Selection ,03 medical and health sciences ,0302 clinical medicine ,medicine ,Humans ,030216 legal & forensic medicine ,Organ donation ,Nicotinic Agonists ,Kidney transplantation ,Cause of death ,Transplantation ,business.industry ,Donor selection ,Graft Survival ,CIGARETTES ,medicine.disease ,3126 Surgery, anesthesiology, intensive care, radiology ,Kidney Transplantation ,Nicotine poisoning ,3. Good health ,Anesthesia ,Tissue and Organ Harvesting ,Surgery ,Female ,medicine.symptom ,Drug Overdose ,business ,medicine.drug - Abstract
Nicotine intoxication is a rare cause of death and can lead to brain death after respiratory arrest and hypoxic-ischemic encephalopathy. To our knowledge, no previous reports regarding organ donation after nicotine intoxication have been described. We present a successful case of kidney donation after brain death caused by subcutaneous nicotine overdose from liquid nicotine from an e-cigarette cartridge in an attempted suicide. Both kidneys were transplanted successfully with immediate graft function, and both recipients were discharged at postoperative day 9 with normal plasma creatinine levels. Graft function has remained excellent in follow-up. This case suggests that kidneys from a donor with fatal nicotine intoxication may be successfully used for kidney transplantation in the absence of other contraindications for donation.
- Published
- 2016