9 results on '"Mikkelsen, Dorte"'
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2. Psychiatric disorders and subsequent risk of cardiovascular disease: a longitudinal matched cohort study across three countries
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Shen, Qing, Mikkelsen, Dorte Helenius, Luitva, Laura Birgit, Song, Huan, Kasela, Silva, Aspelund, Thor, Bergstedt, Jacob, Lu, Yi, Sullivan, Patrick F., Ye, Weimin, Fall, Katja, Tornvall, Per, Pawitan, Yudi, Andreassen, Ole A., Buil, Alfonso, Milani, Lili, Fang, Fang, and Valdimarsdóttir, Unnur
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- 2023
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3. COVID-19 illness severity and 2-year prevalence of physical symptoms:an observational study in Iceland, Sweden, Norway and Denmark
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Shen, Qing, Joyce, Emily E., Ebrahimi, Omid V., Didriksen, Maria, Lovik, Anikó, Sævarsdóttir, Karen Sól, Magnúsdóttir, Ingibjörg, Mikkelsen, Dorte Helenius, Unnarsdóttir, Anna Bára, Hauksdóttir, Arna, Hoffart, Asle, Kähler, Anna K., Thórdardóttir, Edda Björk, Eythórsson, Elías, Frans, Emma M., Tómasson, Gunnar, Ask, Helga, Hardardóttir, Hrönn, Jakobsdóttir, Jóhanna, Lehto, Kelli, Lu, Li, Andreassen, Ole A., Sullivan, Patrick F., Pálsson, Runólfur, Erikstrup, Christian, Ostrowski, Sisse Rye, Werge, Thomas, Aspelund, Thor, Pedersen, Ole B. V., Johnson, Sverre Urnes, Fang, Fang, Valdimarsdóttir, Unnur Anna, Shen, Qing, Joyce, Emily E., Ebrahimi, Omid V., Didriksen, Maria, Lovik, Anikó, Sævarsdóttir, Karen Sól, Magnúsdóttir, Ingibjörg, Mikkelsen, Dorte Helenius, Unnarsdóttir, Anna Bára, Hauksdóttir, Arna, Hoffart, Asle, Kähler, Anna K., Thórdardóttir, Edda Björk, Eythórsson, Elías, Frans, Emma M., Tómasson, Gunnar, Ask, Helga, Hardardóttir, Hrönn, Jakobsdóttir, Jóhanna, Lehto, Kelli, Lu, Li, Andreassen, Ole A., Sullivan, Patrick F., Pálsson, Runólfur, Erikstrup, Christian, Ostrowski, Sisse Rye, Werge, Thomas, Aspelund, Thor, Pedersen, Ole B. V., Johnson, Sverre Urnes, Fang, Fang, and Valdimarsdóttir, Unnur Anna
- Abstract
Background: Although the persistence of physical symptoms after SARS-CoV-2 infection is a major public health concern, evidence from large observational studies beyond one year post diagnosis remain scarce. We aimed to assess the prevalence of physical symptoms in relation to acute illness severity up to more than 2-years after diagnosis of COVID-19. Methods: This multinational study included 64,880 adult participants from Iceland, Sweden, Denmark, and Norway with self-reported data on COVID-19 and physical symptoms from April 2020 to August 2022. We compared the prevalence of 15 physical symptoms, measured by the Patient Health Questionnaire (PHQ-15), among individuals with or without a confirmed COVID-19 diagnosis, by acute illness severity, and by time since diagnosis. We additionally assessed the change in symptoms in a subset of Swedish adults with repeated measures, before and after COVID-19 diagnosis. Findings: During up to 27 months of follow-up, 34.5% participants (22,382/64,880) were diagnosed with COVID-19. Individuals who were diagnosed with COVID-19, compared to those not diagnosed, had an overall 37% higher prevalence of severe physical symptom burden (PHQ-15 score ≥15, adjusted prevalence ratio [PR] 1.37 [95% confidence interval [CI] 1.23–1.52]). The prevalence was associated with acute COVID-19 severity: individuals bedridden for seven days or longer presented with the highest prevalence (PR 2.25 [1.85–2.74]), while individuals never bedridden presented with similar prevalence as individuals not diagnosed with COVID-19 (PR 0.92 [0.68–1.24]). The prevalence was statistically significantly elevated among individuals diagnosed with COVID-19 for eight of the fifteen measured symptoms: shortness of breath, chest pain, dizziness, heart racing, headaches, low energy/fatigue, trouble sleeping, and back pain. The analysis of repeated measurements rendered similar results as the main analysis. Interpretation: These data suggest an elevated prevalence of som
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- 2023
4. Infection Polygenic Factors Account for a Small Proportion of the Relationship Between Infections and Mental Disorders
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Shorter, John R., Meijsen, Joeri, Nudel, Ron, Krebs, Morten, Gådin, Jesper, Mikkelsen, Dorte H., Nogueira Avelar e Silva, Raquel, Benros, Michael E., Thompson, Wesley K., Ingason, Andrés, Werge, Thomas, Shorter, John R., Meijsen, Joeri, Nudel, Ron, Krebs, Morten, Gådin, Jesper, Mikkelsen, Dorte H., Nogueira Avelar e Silva, Raquel, Benros, Michael E., Thompson, Wesley K., Ingason, Andrés, and Werge, Thomas
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Background: Several recent studies have suggested a role for infections in the development of mental disorders; however, the genetic contribution to this association is understudied. Methods: We use the iPSYCH case-cohort genotyped sample (n = 65,534) and Danish health care registry data to study the genetic association between infections and mental disorders. To test the hypothesis that these associations are due to genetic pleiotropy, we estimated the genetic correlation between infection and mental disorders. Polygenic risk scores (PRSs) were used to assess whether genetic pleiotropy of infections and mental disorders was mediated by actual infection diagnoses. Results: We observed that schizophrenia, attention-deficit/hyperactivity disorder, major depressive disorder, bipolar disorder, and posttraumatic stress disorder (rg ranging between 0.18 and 0.83), but not autism spectrum disorder and anorexia nervosa, were significantly genetically correlated with infection diagnoses. PRSs for infections were associated with modest increase in risk of attention-deficit/hyperactivity disorder, major depressive disorder, and schizophrenia in the iPSYCH case-cohort (hazard ratios = 1.04 to 1.10) but was not associated with risk of anorexia, autism, or bipolar disorder. Using mediation analysis, we show that infection diagnoses account for only a small proportion (6%–14%) of the risk for mental disorders conferred by infection PRSs. Conclusions: Infections and mental disorders share a modest genetic architecture. Infection PRSs can predict risk of certain mental disorders; however, this effect is moderate. Finally, recorded infections partially explain the relationship between infection PRSs and mental disorders.
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- 2022
5. Cohort Profile:COVIDMENT: COVID-19 cohorts on mental health across six nations
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Unnarsdóttir, Anna Bára, Lovik, Anikó, Fawns-Ritchie, Chloe, Ask, Helga, Kõiv, Kadri, Hagen, Kristen, Didriksen, Maria, Christoffersen, Lea Arregui Nordahl, Garðarsson, Alexander Berg, McIntosh, Andrew, Kähler, Anna K, Campbell, Archie, Hauksdóttir, Arna, Erikstrup, Christian, Mikkelsen, Dorte Helenius, Altschul, Drew, Thordardottir, Edda Bjork, Frans, Emma Maria, Kvale, Gerd, Tómasson, Gunnar, Kariis, Hanna Maria, Jónsdóttir, Harpa Lind, Rúnarsdóttir, Harpa, Magnúsdóttir, Ingibjörg, Eid, Jarle, Jakobsdóttir, Jóhanna, Nielsen, Kaspar René, Kaspersen, Kathrine Agergård, Milani, Lili, Trogstad, Lill-Iren Schou, Yi, Lu, Bruun, Mie Topholm, Sullivan, Patrick F, Magnus, Per Minor, Shen, Qing, Nesvåg, Ragnar, Brandlistuen, Ragnhild E, Mägi, Reedik, Ostrowski, Sisse Rye, Løkhammer, Solveig, Solem, Stian, Reichborn-Kjennerud, Ted, Hansen, Thomas Folkmann, Werge, Thomas, Aspelund, Thor, Porteous, David J, Fang, Fang, Lehto, Kelli, Andreassen, Ole A, Pedersen, Ole Birger Vesterager, Hellard, Stephanie Le, Valdimarsdóttir, Unnur A, Unnarsdóttir, Anna Bára, Lovik, Anikó, Fawns-Ritchie, Chloe, Ask, Helga, Kõiv, Kadri, Hagen, Kristen, Didriksen, Maria, Christoffersen, Lea Arregui Nordahl, Garðarsson, Alexander Berg, McIntosh, Andrew, Kähler, Anna K, Campbell, Archie, Hauksdóttir, Arna, Erikstrup, Christian, Mikkelsen, Dorte Helenius, Altschul, Drew, Thordardottir, Edda Bjork, Frans, Emma Maria, Kvale, Gerd, Tómasson, Gunnar, Kariis, Hanna Maria, Jónsdóttir, Harpa Lind, Rúnarsdóttir, Harpa, Magnúsdóttir, Ingibjörg, Eid, Jarle, Jakobsdóttir, Jóhanna, Nielsen, Kaspar René, Kaspersen, Kathrine Agergård, Milani, Lili, Trogstad, Lill-Iren Schou, Yi, Lu, Bruun, Mie Topholm, Sullivan, Patrick F, Magnus, Per Minor, Shen, Qing, Nesvåg, Ragnar, Brandlistuen, Ragnhild E, Mägi, Reedik, Ostrowski, Sisse Rye, Løkhammer, Solveig, Solem, Stian, Reichborn-Kjennerud, Ted, Hansen, Thomas Folkmann, Werge, Thomas, Aspelund, Thor, Porteous, David J, Fang, Fang, Lehto, Kelli, Andreassen, Ole A, Pedersen, Ole Birger Vesterager, Hellard, Stephanie Le, and Valdimarsdóttir, Unnur A
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- 2022
6. Cohort Profile: COVIDMENT: COVID-19 cohorts on mental health across six nations
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Unnarsdóttir, Anna Bára, primary, Lovik, Anikó , additional, Fawns-Ritchie, Chloe, additional, Ask, Helga, additional, Kõiv, Kadri, additional, Hagen, Kristen, additional, Didriksen, Maria, additional, Christoffersen, Lea Arregui Nordahl, additional, Garðarsson, Alexander Berg, additional, McIntosh, Andrew, additional, Kähler, Anna K, additional, Campbell, Archie, additional, Hauksdóttir, Arna, additional, Erikstrup, Christian, additional, Mikkelsen, Dorte Helenius, additional, Altschul, Drew, additional, Thordardottir, Edda Bjork, additional, Frans, Emma Maria, additional, Kvale, Gerd, additional, Tómasson, Gunnar, additional, Kariis, Hanna Maria, additional, Jónsdóttir, Harpa Lind, additional, Rúnarsdóttir, Harpa, additional, Magnúsdóttir, Ingibjörg, additional, Eid, Jarle, additional, Jakobsdóttir, Jóhanna, additional, Nielsen, Kaspar René, additional, Kaspersen, Kathrine Agergård, additional, Milani, Lili, additional, Trogstad, Lill-Iren Schou, additional, Yi, Lu, additional, Bruun, Mie Topholm, additional, Sullivan, Patrick F, additional, Magnus, Per Minor, additional, Shen, Qing, additional, Nesvåg, Ragnar, additional, Brandlistuen, Ragnhild E, additional, Mägi, Reedik, additional, Ostrowski, Sisse Rye, additional, Løkhammer, Solveig, additional, Solem, Stian, additional, Reichborn-Kjennerud, Ted, additional, Hansen, Thomas Folkmann, additional, Werge, Thomas, additional, Aspelund, Thor, additional, Porteous, David J, additional, Fang, Fang, additional, Lehto, Kelli, additional, Andreassen, Ole A, additional, Pedersen, Ole Birger Vesterager, additional, Hellard, Stephanie Le, additional, and Valdimarsdóttir, Unnur A, additional
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- 2021
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7. Cohort Profile: COVIDMENT: COVID-19 cohorts on mental health across six nations.
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Unnarsdóttir, Anna Bára, Lovik, Anikó, Fawns-Ritchie, Chloe, Ask, Helga, Kõiv, Kadri, Hagen, Kristen, Didriksen, Maria, Christoffersen, Lea Arregui Nordahl, Garðarsson, Alexander Berg, McIntosh, Andrew, Kähler, Anna K, Campbell, Archie, Hauksdóttir, Arna, Erikstrup, Christian, Mikkelsen, Dorte Helenius, Altschul, Drew, Thordardottir, Edda Bjork, Frans, Emma Maria, Kvale, Gerd, and Tómasson, Gunnar
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- 2022
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8. Brug for dialog - et speciale om dialogisk kommunikation i en integrationsindsats
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Mikkelsen, Dorte, Rasmussen, Mette Emilie, and Phillips, Louise Jane
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dialog ,rollemodel ,kommunikation ,kultur ,integration - Abstract
This thesis arises from an in interest in the widespread discourse of dialogue. The specific focus is on the practical use of dialogue in a concrete campaign, which is supposedly dialogic. The examined case is a campaign launched by The Ministry of Integration, which targets parents with an ethnic minority background, and encourages dialogue about ways in which to support their children in the completion of an education. We ask how dialogue is constructed and identify the consequences for parent options with regards to their choice of action within the context. Furthermore, we look at possible ways to improve and develop the case in a more dialogic direction. The empirical data analysed are based on participant observation during six interventions and supplementary interviews with five of the participating parents. In order to conceptualise the communication process and its dialogic character, the thesis draws on dialogic communica-tion theory and social constructionism. With this as the framework, the analysis examines the interrelation of participants and the negotiation and creation of knowledge and identities dur-ing interaction. The main conclusions of the analysis are that in spite of the dialogic intentions, the interven-tions are predominantly characterised by non-dialogic communication. This can be ascribed to the practitioners’ lack of methodological and theoretical knowledge about dialogue, which makes dialogic moments occur only in rare instances and only by chance. Dialogue is ham-pered by three different factors. Firstly, the use of role models is a hindrance for dialogue as it places the participating parents in an unknowing and inferior position. This, in turn, creates a situation in which the parents are expected to learn from the role model instead of engaging actively in common meaning-making. Secondly, dialogue is inhibited by a lack of awareness of the need to facilitate a plurality of different voices along with a simultaneous lack of ac-knowledgement of voices which articulate competing and opposing forms of knowledge. Thirdly, the participating parents’ possibilities for action are limited by the prevalent assump-tion that ethnic minorities are a homogenous group. Based on these findings, the thesis concludes by making concrete suggestions as to how intervention can promote the occurrence of dialogic moments.
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- 2010
9. The ankylosing spondylitis disease activity score (ADAS) better reflects the inflammatory disease processes than BASDAI. - A comparison with biomarkers of inflammation, cartilage and bone turnover in patients with axial spondyloarthritis treated with TNF-blockers.
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Pedersen, Susanne Juhl, Sørensen, Inge Juul, Garnero, P., Johansen, Julia Sidenius, Madsen, Ole Rintek, Tvede, Niels, Hansen, Mikael Secher, Thamsborg, Gorm Milan, Andersen, Lasse Darling, Majgaard, O., Loft, Anne Gitte, Erlendsson, J., Asmussen, Karsten Heller, Jurik, Anne Grethe, Møller, Jakob Møllenbach, Hasselquist, Maria, Mikkelsen, Dorte, Skjødt, Thomas, Hansen, Annette, Østergaard, Mikkel, Pedersen, Susanne Juhl, Sørensen, Inge Juul, Garnero, P., Johansen, Julia Sidenius, Madsen, Ole Rintek, Tvede, Niels, Hansen, Mikael Secher, Thamsborg, Gorm Milan, Andersen, Lasse Darling, Majgaard, O., Loft, Anne Gitte, Erlendsson, J., Asmussen, Karsten Heller, Jurik, Anne Grethe, Møller, Jakob Møllenbach, Hasselquist, Maria, Mikkelsen, Dorte, Skjødt, Thomas, Hansen, Annette, and Østergaard, Mikkel
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- 2010
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