1. Sex-specific differences in HPA axis activity in VLBW preterm newborns
- Author
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Britt J van Keulen, Michelle Romijn, Bibian van der Voorn, Marita de Waard, Michaela F Hartmann, Johannes B van Goudoever, Stefan A Wudy, Joost Rotteveel, and Martijn J J Finken
- Subjects
glucocorticoid ,metabolites ,steroid ,sexual dimorphism ,Diseases of the endocrine glands. Clinical endocrinology ,RC648-665 - Abstract
Objective: Sex-specific differences in hypothalamic–pituitary–adrenal axis activity might explain why male preterm infants are at higher risk of neonatal mortality and morbidity than their female counterparts. We examined whether male and female preterm infants differed in cortisol production and metabolism at 10 days post-p artum. Design and methods: This prospective study included 36 preterm born infants (18 boys) with a very low birth weight (VLBW) (
- Published
- 2021
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