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Introduction Circadian phase and homeostatic sleep drive affect selective visual attention during sleep inertia (SI), a period of cognitive performance decrement upon awakening that dissipates with time. This study examined the combined effects of circadian misalignment and sleep restriction on visual search performance during SI. Methods Twenty adults (mean±standard deviation [SD] age 25.7±4.2 years; 12M, 8F) completed a 39-day protocol. Prior to a 4-day in-laboratory visit, participants maintained habitual 8h sleep schedules for 2 weeks at home. In-laboratory sleep opportunities (1 per day) were timed to induce varying levels of both circadian misalignment and sleep restriction: 8h on night 1, 3h on night 2, and 3h on mornings 3 and 4. After 3 days of recovery sleep at home (unscheduled), participants repeated the entire protocol. SI was assessed with the Serial Visual Search Task, a measure of selective visual attention, ~ 1, 16, and 31 min after electroencephalogram (EEG) verified awakening following each 3h sleep opportunity. The task required participants to determine whether a target was present or absent among nontarget distractors. Outcomes included median reaction times (RT) and number of missed targets. Sleep opportunities with ≥4.5 min of EEG-verified wakefulness in the 30 min prior to scheduled awakening were excluded from analysis. Data were analyzed with mixed-model ANOVA. Results Mean±SD average amount of wakefulness in the 30 min and 10 min prior to SI testing was 1.2±0.11 and 0.43±0.06 minutes, respectively. Following all sleep opportunities, median RT for overall correct responses and for correct response to target absent trials improved with time since awakening (all p Conclusion Reaction speed was impaired during SI regardless of circadian timing or level of homeostatic sleep drive, whereas missing targets appears to be dependent upon circadian phase and the level of homeostatic sleep debt. These findings have important implications for military and first responders. Support (If Any) Office of Naval Research MURI N00014-15-1-2809; NIH TR001082; Undergraduate Research Opportunities Grant, University of Colorado Boulder.

Dans le cadre d'une analyse sociologique de la culture intellectuelle du XVIII e siecle, l'A. met en evidence l'ethique aristocratique qui domine la Republique des lettres de l'epoque, en general, et qui se manifeste dans la production litteraire de Fontenelle, en particulier. Examinant le lien entre les notions de noblesse et de vertu dans les «Eloges» de l'ecrivain, l'A. montre que celui-ci developpe une philosophie morale qui influence l'image du savant moderne.

This essay argues for the emergence of a cultural and epistemological divide between amateur savants and members of the Royal Academy of the Sciences in late Old Regime and revolutionary France and suggests that the amateur ideal rose in significance even as intellectual activity came to be increasingly centralized in the postrevolutionary era. At the crux of the tensions between the amateur ideal and the professionalizing reality in the immediate postrevolutionary period stood Aubin-Louis Millin and his journal, the Magasin Encyclopédique. The essay examines, in particular, the revival in the pages of the Magasin Encyclopédique of interest in Nicolas-Claude Fabri de Peiresc, the seventeenth-century icon of an amateur ideal in which investigations in the natural sciences and scholarship were private, decentralized, often provincial activities. Although the sciences in the revolutionary and Napoleonic eras were often perceived as forward looking and dismissive of the past, this essay finds that a sentimental and nostalgic attachment to the past-to a myth of Peiresc-continued to play an important role in the identity of postrevolutionary men of letters.