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1. Community-Acquired and Healthcare-Associated Sepsis: Characteristics and in-Hospital Mortality in Italy

Author

Gabriella Di Giuseppe, Maria Mitidieri, Federica Cantore, Concetta P. Pelullo, and Maria Pavia

Subjects
community-acquired sepsis, healthcare-associated sepsis, mortality, sepsis, Therapeutics. Pharmacology, RM1-950
Abstract

Background: The main aim of the study was to analyse characteristics of sepsis according to the setting of occurrence and to identify predictors of sepsis-related in-hospital mortality. Methods: 544 medical records of adult patients with a diagnosis of sepsis were consulted and divided into two groups according to the setting where sepsis originated: community-acquired (CA) and healthcare-associated (HA) sepsis. Results: Overall, 257 (47.2%) patients had HA sepsis and the in-hospital death rate was 33.6%. Results of the multiple logistic regression revealed that patients with HA sepsis were significantly more likely to have been admitted from another hospital or ward, to have a ≥1 Charlson’s index, to be immunesuppressed, and to have undergone a surgical intervention during hospitalization. In-hospital deaths were significantly associated with older age, admission from another hospital or ward, need of haemodialysis and mechanical ventilation (MV), whereas they were less likely in patients with HA sepsis as compared with CA sepsis. Conclusion: Community-acquired and HA sepsis show distinct clinical, prognostic and risk factors profiles, and should be managed according to their differential characteristics.

Published
2020
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2. Cancer prevention: Knowledge, attitudes and lifestyle cancer-related behaviors among adolescents in Italy

Author

Concetta Paola Pelullo, Giuseppe Lioi, Maria Mitidieri, Maria Pavia, Gabriella Di Giuseppe, Di Giuseppe, G., Pelullo, C. P., Mitidieri, M., Lioi, G., and Pavia, M.

Subjects
Male, medicine.medical_specialty, Health Knowledge, Attitudes, Practice, Adolescent, Health, Toxicology and Mutagenesis, Physical activity, lcsh:Medicine, lifestyle cancer-related behaviors, Article, 03 medical and health sciences, 0302 clinical medicine, Lifestyle cancer-related behavior, Surveys and Questionnaires, Neoplasms, Health care, medicine, Humans, risk factors, Surveys and Questionnaire, 030212 general & internal medicine, adolescents, Exercise, Life Style, Cancer, Response rate (survey), Cancer prevention, attitudes, business.industry, Prevention, Risk Factor, lcsh:R, Public Health, Environmental and Occupational Health, medicine.disease, Lifestyle, Knowledge, Attitude, Italy, 030220 oncology & carcinogenesis, Family medicine, Female, business, Human
Abstract

This study explores knowledge, attitudes and lifestyle behaviors related to cancer in a sample of adolescents. Data were collected through a self-administered questionnaire. 871 adolescents agreed to participate, with a response rate of 96.8%. Only 26.1% had a good level of knowledge on most risk factors for cancer. Adolescents with both parents employed, with a personal, familiar or friend history of cancer or having received information about cancer prevention from a physician, were more likely to have good knowledge about the risk factors for cancer. In total, 41% of participants declared that they consumed alcohol and 25.3% declared they were current smokers, 19.2% consumed fruits or vegetables more than once a day and 75.2% reported poor physical activity. Older adolescents, with a personal, familiar or friend history of cancer, not having one parent in the healthcare sector or not physically active were significantly more likely to be current smokers, whereas physical activity was significantly more likely in adolescents who had been informed by physicians on cancer prevention, and had one parent in the healthcare sector. This study highlights a need for improved education of adolescents about cancer prevention and lifestyle cancer-related behaviors.

Published
2020

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