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Populations of species living at the edge of their range need long-term and constant monitoring to analyze the number and condition of individuals of the species. When populations fall out of natural phytocenoses in conditions of regulated nature management, it is possible to restore these cenopopulations by repopulation. For optimization of work on structuring of data on populations, a GIS-map of medicinal plants was created. A full set of studies has been carried out for Bupleurum aureum populations, which are experiencing significant anthropogenic pressure near the western border of its range. The species has practically disappeared from the broad-leaved forests of the Predvolga region. The created GIS-map contains information with precise georeferencing of the identified cenopopulations in relation to landscape and soil type. Another block of the GIS-map database contains information on productivity and genetic polymorphism of cenopopulations, which should be taken into account when restoring lost populations.The conducted studies have shown that the share of generative plants of B. aureum in the population decreases when the light intensity decreases in the forest. In this case, individuals preserved in meadows adjacent to the forest are of great importance. It can be assumed that forest edge communities are important key sites for the conservation of forest biodiversity.

See the retraction notice BIO Web of Conferences 138, 00001 (2024), https://doi.org/10.1051/bioconf/202413800001

Maria K Makeeva,1,2 Fatima Yu Daurova,1 Svetlana F Byakova,2 Anna Yu Turkina2 1Conservative Dentistry Department, People’s Friendship University of Russia (RUDN University), Moscow, Russia; 2Therapeutic Dentistry Department, I.M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, RussiaCorrespondence: Maria K MakeevaConservative Dentistry Department, Peoples Friendship University of Russia (RUDN University), Mikluho-Maklaya Street 10-2, Room 267, Moscow 117198, RussiaTel +79057416437Email abrek93@mail.ruAbstract: The pulp and periodontium have obvious relationships that have been described in many studies. Pulp infections may affect periodontal tissues and vice versa. Teeth with endo-perio lesions have a worse prognosis than isolated endodontic or periodontal lesions. Elimination of endodontic and periodontal infections is essential for successful treatment, so co-operation between endodontists and periodontists is necessary. In this clinical case, a 44-year-old male presented with primary periodontal disease with secondary endodontic involvement in his lower right canine because of aggressive periodontitis. There was 10 mm of clinical attachment loss and 8 mm periodontal pocket mesial from the tooth and bone radiolucency periapical and lateral from the root. Periodontal therapy was followed by endodontic treatment. Periodontal therapy included root scaling and planing, treatment of the periodontal pocket with ozone gas, systemic antibiotics, oral hygiene instructions, and chlorhexidine rinsing. Endodontic therapy included root canal instrumentation with rotary endodontic files, irrigation, root canal treatment with ozone gas, and obturation with lateral compaction. Radiographs at a 6-month follow-up appointment showed complete healing of the periapical lesion and alveolar bone lateral to the root. Using an interdisciplinary approach to treat endo-perio lesions provides favorable clinical outcomes. Ozone therapy is beneficial for the successful treatment of endo-perio lesions with narrow periodontal pockets in patients with aggressive periodontitis and poor prognosis.Keywords: endo-perio lesion, ozone therapy, ozone gas

The article is devoted to pragmatic analysis of mass media metaphors which nowadays became a frequent means of information transfer in the political, economical and social world. Illustrative material is acquired by continuous sampling from Internet versions of most popular Russian, English and French print media both of informational and advertising nature which allowed the authors to identify the common, conditioned by globalization problems, and national-cultural vision of the processes occurring in the modern socio-cultural and economical space. The authors also referred to the Russian National Newspaper Corpus. Data content analysis served as the basic research method. It is shown that public speeches of politicians, economists, analytics, managers of different levels and contextual advertising posted in network discourse and aimed at a wide audience most clearly represent metaphor’s manipulative function which presupposes imposing views, formation of necessary attitude towards a certain event or phenomenon. The usage of metaphors is associated with a certain world model existing in the consciousness of representatives of a certain political trend, and spheres of human activity are represented through the perspectives determined by conceptual metaphors. Metaphor determines the style and way of perceiving the object and subject of political, economical and social life, forms the axiological potential of the produced information. Pragmatic analysis of mass media metaphors indicates that axiological characteristics of metaphor’s content fluctuate, the value orientation changes depending on what feature forming the basis of meaning transfer is actualized at the moment.

The article is devoted to the issue of information structuring within the concept «Ecology». Each concept contains various information which constitutes the core and the periphery of the concept and is actualized in the person’s picture of the world. The same information can be regarded differently; the reason is a partial discrepancy in pictures of the world and the difference of gained experience. The information within the concept consists not only of proved knowledge but of associations and representation of each individual as well. Thus, the quantity of information within the concept is considerably large. To systematize the knowledge within the concept models of knowledge representation were introduced; a frame is an example of such a model. In the following article a frame is regarded as a schematic representation of knowledge within the concept consisting of the frame’s name and its slots – well-ordered units which organize the structure of the frame. Having studied frames as the unit of knowledge representation attention is drawn to the peculiarities of frame perception which are determined by their recipients’ characteristics. The names of the slots are usually common for frames of one thematic group unlike their content which is unique for slots of different frames. On the basis of the comparative analysis of «Global warming» frame in Australian and Arctic representatives’ pictures of the world the conclusion has been made that this frame unfolds to its recipients differently due to their location, experience and urgency of the problem in each country.

The present stage of development of our country is distinguished by dynamism and qualitative changes in all spheres of public life. As the information component of the modern economy grows in Russia, the role and importance of the information interaction of an enterprise with representatives of the internal and external business environment increases significantly, and this has a direct impact on the effective functioning of the organization at all stages of its production, sales and management activities. Properly organized processes of receiving, storing, processing and analyzing data within the organization allow us to assess the company state of affairs, plan for the nearest future and assess future prospects, make timely decisions about changing of business policies, reorganizing the structure, timely fulfillment of sales and production plans, and effectively use the employees’ working hours with the greatest benefit to the organization. The set of information flows that ensure an organization interaction with its internal and external representatives forms the information space of the enterprise.

The interaction of different dental alloys with the oral environment may cause severe side effects (e.g., burning sensation, inflammatory reactions, carcinogenesis) as a result of oral galvanism. However, the pathogenesis of side effects associated with oral galvanism is still unclear, and the effects of direct current and alloy corrosion ions are considered potentially contributing factors. Therefore, the aim of this study was to systemically compare the damaging effects of (1) galvanism as a synergistic process (direct current + corrosion ions), (2) direct current separately, and (3) corrosion ions separately on an in vitro mucosa-like model based on a cell line of immortalized human keratinocytes (HaCaTs) to reveal the factors playing a pivotal role in dental alloys side effects. For this, we chose and compared the dental alloys with the highest risk of oral galvanism: Ti64-AgPd and NiCr-AgPd. We showed that galvanic current may be the leading damaging factor in the cytotoxic processes associated with galvanic coupling of metallic intraoral appliances in the oral cavity, especially in the short-term period (28 days). However, the contribution of corrosion ions (Ni 2+ ) to the synergistic toxicity was also shown, and quite possibly, in the long term, it could be no less dangerous.

Background: chronic apical periodontitis is a common pathology in dentistry, especially in endodontics. It is necessary to systematize data concerning commonly used irrigation solutions. The development of new protocols for endodontic treatment is a very promising direction. The use of a polyhexanide-based antiseptic can positively affect the results of endodontic treatment., Methods: the review was carried out involving the search for English language research and meta-analyses in the Google Scholar and PubMed databases., Results: the number of literary sources that were identified during the literature review is 180. After excluding publications that did not match the search criteria, the total number of articles included in the systematic review was determined to be 68., Conclusions: polyhexanide is a promising solution for infected root canal irrigation. The antibacterial activity of this substance is suitable for the elimination of pathogens responsible for the appearance of apical periodontitis.

Calcineurin is a calcium-dependent phosphatase that is involved in many cellular processes including hypertrophy. Inhibition or genetic loss of calcineurin blocks pathological cardiac hypertrophy and diabetic renal hypertrophy. However, calcineurin does not appear to be involved in physiological cardiac hypertrophy induced by exercise. The role of calcineurin in a compensatory, non-pathological model of renal hypertrophy has not been tested. Therefore, in this study, we examined activation of calcineurin and the effect of calcineurin inhibition or knockout on compensatory hypertrophy following uninephrectomy (UNX). UNX induces ~15% increase in the size of the remaining kidney; the data show no change in the generation of reactive oxygen species (ROS), Nox4 or transforming growth factor-β expression confirming the model as one of compensatory hypertrophy. Next, analyses of the remaining kidney reveal that total calcineurin activity is increased, and, to a lesser extent, transcriptional activity of the calcineurin substrate nuclear factor of activated T cell is up-regulated following UNX. However, inhibition of calcineurin with cyclosporine failed to prevent compensatory renal hypertrophy. Likewise, hypertrophy was comparable to WT in mice lacking either isoform of the catalytic subunit of calcineurin (CnAα-/- or CnAβ-/-). In conclusion, similar to its role in the heart, calcineurin is required for pathological but not compensatory renal hypertrophy. This separation of signalling pathways could therefore help further define key factors necessary for pathological hypertrophy including diabetic nephropathy., (© 2014 The Authors. Journal of Cellular and Molecular Medicine published by John Wiley & Sons Ltd and Foundation for Cellular and Molecular Medicine.)