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1. Wave packet scattering in porous planar semiconductor channel

Author

Lopes, D. S., de Sousa, A. A., de Sousa, J. S., da Costa, D. R., and Pereira, T. A. S.

Subjects
Condensed Matter - Mesoscale and Nanoscale Physics, 81U08, I.6.6
Abstract

In this work, we investigate the dynamics of the wave packet traveling through a porous semiconductor channel, with the defects being simulated by a disordered scattering region produced by obstruction potentials. The theoretical framework is based on the $split-operator$ technique to solve the time-dependent Schr$\"o$dinger equation within the effective mass approximation. In our simulation, we consider the semiconductor channel made by InGaAs with a width of 100 angstrom, growth on an InAlAs substrate, and the porous ones with circular symmetry and different densities. The results for the current probability density and reflection, and transmission coefficients are analyzed for different initial values of the kinetic energy of the Gaussian wave packet, disordered pore densities, and pore randomness., Comment: The title of the work will have to be changed and the results will have to be more widely discussed

Published
2023

2. DO ANALÓGICO AO DIGITAL: O JOGO PANDEMIC COMO POTENCIAL PEDAGÓGICO PARA O ENSINO DE CIÊNCIAS EM AMBIENTES DIGITAIS.

Author

LOPES, D. S. and ALVES, L. R. G.

Abstract

Since the Covid-19 Pandemic, growth in the sale/interaction of/with digital games has been recorded. This study analyzed the contributions of digital games that bring information linked to Health in their narratives, in this case, to the epidemiological aspects of a Pandemic. To this end, based on a survey of the literature, referring to the relationship between digital games and digital teaching spaces, the Pandemic game was chosen as the object of study due to its hybrid characteristic (Analogical/Digital), being analyzed through the principles of Heuristic Assessment of Gameplay. After analysis, the potential of this digital artifact for discussing the Biology curriculum was highlighted, in addition to the specific development of a didactic sequence linked to the contents of the area. It was possible to see that games, like Pandemic, are capable of contributing to the development of pedagogical interventions that directly and indirectly deal with health issues involving a health crisis, such as a Pandemic. [ABSTRACT FROM AUTHOR]

Published
2023
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4. Action of neuwiedase, a metalloproteinase isolated from Bothrops neuwiedi venom, on skeletal muscle: An ultrastructural and immunocytochemistry study

Author

Baldo, C., Ferreira, M. J., Lopes, D. S., Izidoro, L. F. M., Gomes, A. O., Eloisa Ferro, Hamaguchi, A., Homsi-Brandeburgo, M. I., and Rodrigues, V. M.

Subjects
Bothrops neuwiedi, neuwiedase, snake venom metalloproteinases, skeletal muscle, musculoskeletal system
Abstract

The damaging effects of neuwiedase, a non-hemorrhagic snake venom metalloproteinase from P-I class, on gastrocnemius muscle are studied herein. Following neuwiedase injection, ultrastructural alterations were detected early showing disarrangement of skeletal muscle fibers (characterized by discontinuity of Z lines), mitochondrial swelling, and disruption of plasma membrane and basal lamina. Degradation of skeletal muscle and the appearance of an amorphous substance, primarily composed of cellular debris, were noted after 24 hours. The presence of neuwiedase at the injection site (detected by immunocytochemistry) revealed highly specific labeling of myofibril components of damaged myocytes. In addition, proteolysis of muscle proteins assayed through myofibrils extracted from gastrocnemius muscle indicated that neuwiedase provoked degradation of myofibrils, especially myosin. These results suggest that skeletal muscle damage, induced by neuwiedase, is probably due to its proteolytic action on myofibrils, which are responsible for the maintenance of the cellular architecture.

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