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1. Tumor mutational load is prognostic for progression to therapy among high-count monoclonal B-cell lymphocytosis

Author

Kleinstern, Geffen, Boddicker, Nicholas J., O’Brien, Daniel R., Allmer, Cristine, Rabe, Kari G., Norman, Aaron D., Griffin, Rosalie, Yan, Huihuang, Ma, Tao, Call, Timothy G., Bruins, Laura, Brown, Sochilt, Bonolo de Campos, Cecilia, Hanson, Curtis A., Leis, Jose F., Ding, Wei, Vachon, Celine M., Kay, Neil E., Oakes, Christopher C., Parker, Alexander S., Brander, Danielle M., Weinberg, J. Brice, Furman, Richard R., Shanafelt, Tait D., Cerhan, James R., Parikh, Sameer A., Braggio, Esteban, and Slager, Susan L.

Published
2024
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2. Artificial Intelligence Electrocardiography to Predict Atrial Fibrillation in Patients With Chronic Lymphocytic Leukemia

Author

Christopoulos, Georgios, Attia, Zachi I., Achenbach, Sara J., Rabe, Kari G., Call, Timothy G., Ding, Wei, Leis, Jose F., Muchtar, Eli, Kenderian, Saad S., Wang, Yucai, Hampel, Paul J., Koehler, Amber B., Kay, Neil E., Kapoor, Prashant, Slager, Susan L., Shanafelt, Tait D., Noseworthy, Peter A., Friedman, Paul A., Herrmann, Joerg, and Parikh, Sameer A.

Published
2024
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3. Differential prognosis of single and multiple TP53 abnormalities in high-count MBL and untreated CLL

Author

Griffin, Rosalie, Wiedmeier-Nutor, Julia E., Parikh, Sameer A., McCabe, Chantal E., O'Brien, Daniel R., Boddicker, Nicholas J., Kleinstern, Geffen, Rabe, Kari G., Bruins, Laura, Brown, Sochilt, Bonolo de Campos, Cecilia, Ding, Wei, Leis, Jose F., Hampel, Paul J., Call, Timothy G., Van Dyke, Daniel L., Kay, Neil E., Cerhan, James R., Yan, Huihuang, Slager, Susan L., and Braggio, Esteban

Published
2023
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4. Ibrutinib–Rituximab or Chemoimmunotherapy for Chronic Lymphocytic Leukemia

Author

Shanafelt, Tait D, Wang, Xin V, Kay, Neil E, Hanson, Curtis A, O'Brien, Susan, Barrientos, Jacqueline, Jelinek, Diane F, Braggio, Esteban, Leis, Jose F, Zhang, Cong C, Coutre, Steven E, Barr, Paul M, Cashen, Amanda F, Mato, Anthony R, Singh, Avina K, Mullane, Michael P, Little, Richard F, Erba, Harry, Stone, Richard M, Litzow, Mark, and Tallman, Martin

Subjects
Biomedical and Clinical Sciences, Cardiovascular Medicine and Haematology, Oncology and Carcinogenesis, Orphan Drug, Clinical Research, Clinical Trials and Supportive Activities, Hematology, Rare Diseases, Cancer, Lymphoma, 6.1 Pharmaceuticals, Evaluation of treatments and therapeutic interventions, Good Health and Well Being, Adenine, Aged, Antineoplastic Combined Chemotherapy Protocols, Cyclophosphamide, Female, Humans, Immunotherapy, Intention to Treat Analysis, Kaplan-Meier Estimate, Leukemia, Lymphocytic, Chronic, B-Cell, Male, Middle Aged, Piperidines, Progression-Free Survival, Pyrazoles, Pyrimidines, Rituximab, Vidarabine, Medical and Health Sciences, General & Internal Medicine, Biomedical and clinical sciences, Health sciences
Abstract

BackgroundData regarding the efficacy of treatment with ibrutinib-rituximab, as compared with standard chemoimmunotherapy with fludarabine, cyclophosphamide, and rituximab, in patients with previously untreated chronic lymphocytic leukemia (CLL) have been limited.MethodsIn a phase 3 trial, we randomly assigned (in a 2:1 ratio) patients 70 years of age or younger with previously untreated CLL to receive either ibrutinib and rituximab for six cycles (after a single cycle of ibrutinib alone), followed by ibrutinib until disease progression, or six cycles of chemoimmunotherapy with fludarabine, cyclophosphamide, and rituximab. The primary end point was progression-free survival, and overall survival was a secondary end point. We report the results of a planned interim analysis.ResultsA total of 529 patients underwent randomization (354 patients to the ibrutinib-rituximab group, and 175 to the chemoimmunotherapy group). At a median follow-up of 33.6 months, the results of the analysis of progression-free survival favored ibrutinib-rituximab over chemoimmunotherapy (89.4% vs. 72.9% at 3 years; hazard ratio for progression or death, 0.35; 95% confidence interval [CI], 0.22 to 0.56; P

Published
2019

5. Long-term outcomes for ibrutinib–rituximab and chemoimmunotherapy in CLL: updated results of the E1912 trial

Author

Shanafelt, Tait D., Wang, Xin Victoria, Hanson, Curtis A., Paietta, Elisabeth M., O'Brien, Susan, Barrientos, Jacqueline, Jelinek, Diane F., Braggio, Esteban, Leis, Jose F., Zhang, Cong Christine, Coutre, Steven E., Barr, Paul M., Cashen, Amanda F., Mato, Anthony R., Singh, Avina K., Mullane, Michael P., Little, Richard F., Erba, Harry, Stone, Richard M., Litzow, Mark, Tallman, Martin, and Kay, Neil E.

Published
2022
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6. Clinical outcomes in patients with chronic lymphocytic leukemia with disease progression on ibrutinib

Author

Hampel, Paul J., Rabe, Kari G., Call, Timothy G., Ding, Wei, Leis, Jose F., Chanan-Khan, Asher A., Kenderian, Saad S., Muchtar, Eli, Wang, Yucai, Ailawadhi, Sikander, Koehler, Amber B., Parrondo, Ricardo, Schwager, Susan M., Sher, Taimur, Hanson, Curtis A., Shi, Min, Van Dyke, Daniel L., Braggio, Esteban, Slager, Susan L., Kay, Neil E., and Parikh, Sameer A.

Published
2022
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8. Natural history of monoclonal B-cell lymphocytosis among relatives in CLL families

Author

Slager, Susan L., Lanasa, Mark C., Marti, Gerald E., Achenbach, Sara J., Camp, Nicola J., Abbasi, Fatima, Kay, Neil E., Vachon, Celine M., Cerhan, James R., Johnston, James B., Call, Timothy G., Rabe, Kari G., Kleinstern, Geffen, Boddicker, Nicholas J., Norman, Aaron D., Parikh, Sameer A., Leis, Jose F., Banerji, Versha, Brander, Danielle M., Glenn, Martha, Ferrajoli, Alessandra, Curtin, Karen, Braggio, Esteban, Shanafelt, Tait D., McMaster, Mary L., Weinberg, J. Brice, Hanson, Curtis A., and Caporaso, Neil E.

Published
2021
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9. Tolerability and long-term disease control by IGHV mutation status among patients with CLL on ibrutinib arm of E1912

Author

Shanafelt, Tait D., Wang, Xin Victoria, Hanson, Curtis A., Paietta, Elisabeth, O’Brien, Susan, Barrientos, Jacqueline, Jelinek, Diane F., Braggio, Esteban, Leis, Jose F., Zhang, Cong Christine, Barr, Paul M., Cashen, Amanda F., Mato, Anthony R., Singh, Avina K., Mullane, Michael P., Little, Richard F., Erba, Harry, Stone, Richard M., Litzow, Mark, Tallman, Martin, and Kay, Neil E.

Published
2025
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10. Atrial fibrillation in patients with chronic lymphocytic leukemia (CLL) treated with ibrutinib: risk prediction, management, and clinical outcomes

Author

Archibald, William J., Rabe, Kari G., Kabat, Brian F., Herrmann, Joerg, Ding, Wei, Kay, Neil E., Kenderian, Saad S., Muchtar, Eli, Leis, Jose F., Wang, Yucai, Chanan-Khan, Asher A., Schwager, Susan M., Koehler, Amber B., Fonder, Amie L., Slager, Susan L., Shanafelt, Tait D., Call, Timothy G., and Parikh, Sameer A.

Published
2021
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11. Chronic lymphocytic leukemia (CLL) with Reed–Sternberg-like cells vs Classic Hodgkin lymphoma transformation of CLL: does this distinction matter?

Author

King, Rebecca L., Gupta, Alia, Kurtin, Paul J., Ding, Wei, Call, Timothy G., Rabe, Kari G., Kenderian, Saad S., Leis, Jose F., Wang, Yucai, Schwager, Susan M., Slager, Susan L., Kay, Neil. E., Koehler, Amber, Ansell, Stephen M., Inwards, David J., Habermann, Thomas M., Shi, Min, Hanson, Curtis A., Howard, Matthew T., and Parikh, Sameer A.

Published
2022
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14. Association of polygenic risk score with the risk of chronic lymphocytic leukemia and monoclonal B-cell lymphocytosis

Author

Kleinstern, Geffen, Camp, Nicola J., Goldin, Lynn R., Vachon, Celine M., Vajdic, Claire M., de Sanjose, Silvia, Weinberg, J. Brice, Benavente, Yolanda, Casabonne, Delphine, Liebow, Mark, Nieters, Alexandra, Hjalgrim, Henrik, Melbye, Mads, Glimelius, Bengt, Adami, Hans-Olov, Boffetta, Paolo, Brennan, Paul, Maynadie, Marc, McKay, James, Cocco, Pier Luigi, Shanafelt, Tait D., Call, Timothy G., Norman, Aaron D., Hanson, Curtis, Robinson, Dennis, Chaffee, Kari G., Brooks-Wilson, Angela R., Monnereau, Alain, Clavel, Jacqueline, Glenn, Martha, Curtin, Karen, Conde, Lucia, Bracci, Paige M., Morton, Lindsay M., Cozen, Wendy, Severson, Richard K., Chanock, Stephen J., Spinelli, John J., Johnston, James B., Rothman, Nathaniel, Skibola, Christine F., Leis, Jose F., Kay, Neil E., Smedby, Karin E., Berndt, Sonja I., Cerhan, James R., Caporaso, Neil, and Slager, Susan L.

Published
2018
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15. Genome-wide association study identifies multiple risk loci for chronic lymphocytic leukemia

Author

Berndt, Sonja I, Skibola, Christine F, Joseph, Vijai, Camp, Nicola J, Nieters, Alexandra, Wang, Zhaoming, Cozen, Wendy, Monnereau, Alain, Wang, Sophia S, Kelly, Rachel S, Lan, Qing, Teras, Lauren R, Chatterjee, Nilanjan, Chung, Charles C, Yeager, Meredith, Brooks-Wilson, Angela R, Hartge, Patricia, Purdue, Mark P, Birmann, Brenda M, Armstrong, Bruce K, Cocco, Pierluigi, Zhang, Yawei, Severi, Gianluca, Zeleniuch-Jacquotte, Anne, Lawrence, Charles, Burdette, Laurie, Yuenger, Jeffrey, Hutchinson, Amy, Jacobs, Kevin B, Call, Timothy G, Shanafelt, Tait D, Novak, Anne J, Kay, Neil E, Liebow, Mark, Wang, Alice H, Smedby, Karin E, Adami, Hans-Olov, Melbye, Mads, Glimelius, Bengt, Chang, Ellen T, Glenn, Martha, Curtin, Karen, Cannon-Albright, Lisa A, Jones, Brandt, Diver, W Ryan, Link, Brian K, Weiner, George J, Conde, Lucia, Bracci, Paige M, Riby, Jacques, Holly, Elizabeth A, Smith, Martyn T, Jackson, Rebecca D, Tinker, Lesley F, Benavente, Yolanda, Becker, Nikolaus, Boffetta, Paolo, Brennan, Paul, Foretova, Lenka, Maynadie, Marc, McKay, James, Staines, Anthony, Rabe, Kari G, Achenbach, Sara J, Vachon, Celine M, Goldin, Lynn R, Strom, Sara S, Lanasa, Mark C, Spector, Logan G, Leis, Jose F, Cunningham, Julie M, Weinberg, J Brice, Morrison, Vicki A, Caporaso, Neil E, Norman, Aaron D, Linet, Martha S, De Roos, Anneclaire J, Morton, Lindsay M, Severson, Richard K, Riboli, Elio, Vineis, Paolo, Kaaks, Rudolph, Trichopoulos, Dimitrios, Masala, Giovanna, Weiderpass, Elisabete, Chirlaque, María-Dolores, Vermeulen, Roel CH, Travis, Ruth C, Giles, Graham G, Albanes, Demetrius, Virtamo, Jarmo, Weinstein, Stephanie, Clavel, Jacqueline, Zheng, Tongzhang, Holford, Theodore R, Offit, Kenneth, Zelenetz, Andrew, Klein, Robert J, Spinelli, John J, and Bertrand, Kimberly A

Subjects
Biological Sciences, Genetics, Lymphatic Research, Cancer Genomics, Cancer, Hematology, Prevention, Lymphoma, Rare Diseases, Human Genome, Case-Control Studies, Chromosomes, Human, Pair 2, Genetic Loci, Genetic Predisposition to Disease, Genome-Wide Association Study, Humans, Leukemia, Lymphocytic, Chronic, B-Cell, Linkage Disequilibrium, Polymorphism, Single Nucleotide, Recombination, Genetic, Risk, Medical and Health Sciences, Developmental Biology, Agricultural biotechnology, Bioinformatics and computational biology
Abstract

Genome-wide association studies (GWAS) have previously identified 13 loci associated with risk of chronic lymphocytic leukemia or small lymphocytic lymphoma (CLL). To identify additional CLL susceptibility loci, we conducted the largest meta-analysis for CLL thus far, including four GWAS with a total of 3,100 individuals with CLL (cases) and 7,667 controls. In the meta-analysis, we identified ten independent associated SNPs in nine new loci at 10q23.31 (ACTA2 or FAS (ACTA2/FAS), P=1.22×10(-14)), 18q21.33 (BCL2, P=7.76×10(-11)), 11p15.5 (C11orf21, P=2.15×10(-10)), 4q25 (LEF1, P=4.24×10(-10)), 2q33.1 (CASP10 or CASP8 (CASP10/CASP8), P=2.50×10(-9)), 9p21.3 (CDKN2B-AS1, P=1.27×10(-8)), 18q21.32 (PMAIP1, P=2.51×10(-8)), 15q15.1 (BMF, P=2.71×10(-10)) and 2p22.2 (QPCT, P=1.68×10(-8)), as well as an independent signal at an established locus (2q13, ACOXL, P=2.08×10(-18)). We also found evidence for two additional promising loci below genome-wide significance at 8q22.3 (ODF1, P=5.40×10(-8)) and 5p15.33 (TERT, P=1.92×10(-7)). Although further studies are required, the proximity of several of these loci to genes involved in apoptosis suggests a plausible underlying biological mechanism.

Published
2013

17. Genome-wide association study of follicular lymphoma identifies a risk locus at 6p21.32

Author

Conde, Lucia, Halperin, Eran, Akers, Nicholas K, Brown, Kevin M, Smedby, Karin E, Rothman, Nathaniel, Nieters, Alexandra, Slager, Susan L, Brooks-Wilson, Angela, Agana, Luz, Riby, Jacques, Liu, Jianjun, Adami, Hans-Olov, Darabi, Hatef, Hjalgrim, Henrik, Low, Hui-Qi, Humphreys, Keith, Melbye, Mads, Chang, Ellen T, Glimelius, Bengt, Cozen, Wendy, Davis, Scott, Hartge, Patricia, Morton, Lindsay M, Schenk, Maryjean, Wang, Sophia S, Armstrong, Bruce, Kricker, Anne, Milliken, Sam, Purdue, Mark P, Vajdic, Claire M, Boyle, Peter, Lan, Qing, Zahm, Shelia H, Zhang, Yawei, Zheng, Tongzhang, Becker, Nikolaus, Benavente, Yolanda, Boffetta, Paolo, Brennan, Paul, Butterbach, Katja, Cocco, Pierluigi, Foretova, Lenka, Maynadié, Marc, de Sanjosé, Silvia, Staines, Anthony, Spinelli, John J, Achenbach, Sara J, Call, Timothy G, Camp, Nicola J, Glenn, Martha, Caporaso, Neil E, Cerhan, James R, Cunningham, Julie M, Goldin, Lynn R, Hanson, Curtis A, Kay, Neil E, Lanasa, Mark C, Leis, Jose F, Marti, Gerald E, Rabe, Kari G, Rassenti, Laura Z, Spector, Logan G, Strom, Sara S, Vachon, Celine M, Weinberg, J Brice, Holly, Elizabeth A, Chanock, Stephen, Smith, Martyn T, Bracci, Paige M, and Skibola, Christine F

Subjects
Biological Sciences, Genetics, Rare Diseases, Lymphatic Research, Lymphoma, Human Genome, Prevention, Cancer, Hematology, 2.1 Biological and endogenous factors, Disease Susceptibility, Genetic Variation, Genome-Wide Association Study, Humans, Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Major Histocompatibility Complex, Risk Factors, Medical and Health Sciences, Developmental Biology, Agricultural biotechnology, Bioinformatics and computational biology
Abstract

To identify susceptibility loci for non-Hodgkin lymphoma subtypes, we conducted a three-stage genome-wide association study. We identified two variants associated with follicular lymphoma at 6p21.32 (rs10484561, combined P = 1.12 x 10(-29) and rs7755224, combined P = 2.00 x 10(-19); r(2) = 1.0), supporting the idea that major histocompatibility complex genetic variation influences follicular lymphoma susceptibility. We also found confirmatory evidence of a previously reported association between chronic lymphocytic leukemia/small lymphocytic lymphoma and rs735665 (combined P = 4.24 x 10(-9)).

Published
2010

18. Pembrolizumab in patients with CLL and Richter transformation or with relapsed CLL

Author

Ding, Wei, LaPlant, Betsy R., Call, Timothy G., Parikh, Sameer A., Leis, Jose F., He, Rong, Shanafelt, Tait D., Sinha, Sutapa, Le-Rademacher, Jennifer, Feldman, Andrew L., Habermann, Thomas M., Witzig, Thomas E., Wiseman, Gregory A., Lin, Yi, Asmus, Erik, Nowakowski, Grzegorz S., Conte, Michael J., Bowen, Deborah A., Aitken, Casey N., Van Dyke, Daniel L., Greipp, Patricia T., Liu, Xin, Wu, Xiaosheng, Zhang, Henan, Secreto, Charla R., Tian, Shulan, Braggio, Esteban, Wellik, Linda E., Micallef, Ivana, Viswanatha, David S., Yan, Huihuang, Chanan-Khan, Asher A., Kay, Neil E., Dong, Haidong, and Ansell, Stephen M.

Published
2017
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20. DTRMWXHS ‐12, a novel Bruton tyrosine kinase inhibitor, in combination with everolimus and pomalidomide in patients with relapsed/refractory lymphomas: An open‐label, multicenter, phase 1a/1b study

Author

Huntington, Scott F., primary, Schuster, Stephen J., additional, Ding, Wei, additional, Koehler, Amber B., additional, Brander, Danielle M., additional, Rosenthal, Allison C., additional, Leis, Jose F., additional, Tun, Han W., additional, Moustafa, Muhamad Alhaj, additional, Iqbal, Madiha, additional, He, Wei, additional, Kearney, Albert S., additional, McKinlay, Timothy P., additional, Gui, Min, additional, and Mato, Anthony R., additional

Published
2023
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21. Low Incidence of Fungal Infections after Chimeric Antigen Receptor T-Cell Therapy for Non-Hodgkin Lymphoma in an Endemic Region for Coccidioidomycosis

Author

Gaulin, Charles, primary, Ulrickson, Matthew L., additional, Husnain, Muhammad, additional, Iqbal, Madiha, additional, Vergidis, Paschalis, additional, Rosenthal, Allison, additional, Murthy, Hemant, additional, Mead-Harvey, Carolyn, additional, Wang, Yucai, additional, Castro, Januario E., additional, Palmer, Jeanne, additional, Leis, Jose F., additional, Johnston, Patrick B., additional, Blair, Janis, additional, Kharfan-Dabaja, Mohamed A., additional, Lin, Yi, additional, and Muñoz, Javier, additional

Published
2023
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23. Nonmyeloablative Allogeneic Hematopoietic Stem Cell Transplant for the Treatment of Patients with Hematologic Malignancies Using Busulfan, Fludarabine, and Total Body Irradiation Conditioning Is Effective in an Elderly and Infirm Population

Author

Brammer, Jonathan E., Stentz, Alexander, Gajewski, James, Curtin, Peter, Hayes-Lattin, Brandon, Kovacsovics, Tibor, Leis, Jose F., Meyers, Gabrielle, Nemecek, Eneida, Subbiah, Nan, Frires, Rachel, Palmbach, Gundula, Avraham, Galit Perets, Slater, Susan, and Maziarz, Richard T.

Published
2015
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24. Comparison of Treatment-Emergent Adverse Events of Covalent BTK Inhibitors in Clinical Trials in B-Cell Malignancies: A Systematic Review and Meta-Analysis

Author

Wang, Jacqueline F, primary, Hwang, Steven R, additional, Jiang, Yi, additional, Qi, Xinyue, additional, Zhang, Shijia, additional, Parikh, Sameer A., additional, Ding, Wei, additional, Kenderian, Saad S., additional, Muchtar, Eli, additional, Hampel, Paul J., additional, Leis, Jose F., additional, Munoz, Javier L, additional, Thanarajasingam, Gita, additional, Paludo, Jonas, additional, Inwards, David J., additional, Nowakowski, Grzegorz S., additional, Ansell, Stephen M., additional, Habermann, Thomas M., additional, Witzig, Thomas E., additional, Kay, Neil E., additional, Zhou, Shouhao, additional, and Wang, Yucai, additional

Published
2022
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25. Treatment Patterns and Outcomes of Patients with Chronic Lymphocytic Leukemia with TP53 Mutations

Author

Hwang, Steven R, primary, Wang, Yucai, additional, Rabe, Kari G, additional, He, Rong, additional, Kenderian, Saad S., additional, Muchtar, Eli, additional, Hampel, Paul J., additional, Kay, Neil E., additional, Call, Timothy G., additional, Koehler, Amber, additional, Behnken, Amy L, additional, Leis, Jose F., additional, Braggio, Esteban, additional, Shi, Min, additional, Viswanatha, David S., additional, Van Dyke, Daniel L., additional, Slager, Susan L., additional, Parikh, Sameer A., additional, and Ding, Wei, additional

Published
2022
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26. Low Incidence of Fungal Infections after Chimeric Antigen Receptor T-Cell Therapy for Non-Hodgkin Lymphoma in an Endemic Region for Coccidioidomycosis

Author

Gaulin, Charles, primary, Ulrickson, Matthew, additional, Husnain, Muhammad, additional, Iqbal, Madiha, additional, Vergidis, Paschalis, additional, Rosenthal, Allison C., additional, Murthy, Hemant S., additional, Mead-Harvey, Carolyn, additional, Wang, Yucai, additional, Castro, Januario E., additional, Palmer, Jeanne M., additional, Leis, Jose F., additional, Johnston, Patrick B., additional, Blair, Janis E., additional, Kharfan-Dabaja, Mohamed A., additional, Lin, Yi, additional, and Munoz, Javier, additional

Published
2022
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29. Outcomes of Human Leukocyte Antigen–Matched Sibling Donor Hematopoietic Cell Transplantation in Chronic Lymphocytic Leukemia: Myeloablative Versus Reduced-Intensity Conditioning Regimens

Author

Sobecks, Ronald M., Leis, Jose F., Gale, Robert Peter, Ahn, Kwang Woo, Zhu, Xiaochun, Sabloff, Mitchell, de Lima, Marcos, Brown, Jennifer R., Inamoto, Yoshihiro, Hale, Gregory A., Aljurf, Mahmoud D., Kamble, Rammurti T., Hsu, Jack W., Pavletic, Steven Z., Wirk, Baldeep, Seftel, Matthew D., Lewis, Ian D., Alyea, Edwin P., Cortes, Jorge, Kalaycio, Matt E., Maziarz, Richard T., and Saber, Wael

Published
2014
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30. Reduced Toxicity Conditioning and Allogeneic Stem Cell Transplantation in Adults Using Fludarabine, Carmustine, Melphalan, and Antithymocyte Globulin: Outcomes Depend on Disease Risk Index but Not Age, Comorbidity Score, Donor Type, or Human Leukocyte Antigen Mismatch

Author

Slack, James L., Dueck, Amylou C., Fauble, Veena D., Sproat, Lisa O., Reeder, Craig B., Noel, Pierre, Khera, Nandita, Betcher, Jeffery A., Klein, Jared L., Leis, Jose F., and Adams, Roberta H.

Published
2013
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31. Genome-wide association study identifies a novel susceptibility locus at 6p21.3 among familial CLL

Author

Slager, Susan L., Rabe, Kari G., Achenbach, Sara J., Vachon, Celine M., Goldin, Lynn R., Strom, Sara S., Lanasa, Mark C., Spector, Logan G., Rassenti, Laura Z., Leis, Jose F., Camp, Nicola J., Glenn, Martha, Kay, Neil E., Cunningham, Julie M., Hanson, Curtis A., Marti, Gerald E., Weinberg, J. Brice, Morrison, Vicki A., Link, Brian K., Call, Timothy G., Caporaso, Neil E., and Cerhan, James R.

Published
2011
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32. Quality of Life in Patients <=70 Years of Age with Chronic Lymphocytic Leukemia Treated Frontline with Ibrutinib-Rituximab Versus Fludarabine Cyclophosphamide Rituximab: Analysis from ECOG-ACRIN E1912

Author

Pophali, Priyanka A, primary, Wang, Xin Victoria, additional, Zhao, Fengmin, additional, Kay, Neil E., additional, Hanson, Curtis A., additional, Thomas, Mary L., additional, O'Brien, Susan M., additional, Barrientos, Jacqueline, additional, Paietta, Elisabeth M., additional, Leis, Jose F., additional, Zhang, Cong Christine, additional, Coutre, Steven, additional, Barr, Paul M., additional, Cashen, Amanda, additional, Mato, Anthony R., additional, Singh, Avina, additional, Little, Richard F., additional, Erba, Harry P., additional, Stone, Richard M., additional, Litzow, Mark R., additional, Tallman, Martin S., additional, Shanafelt, Tait, additional, and Wagner, Lynne I., additional

Published
2021
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33. Humoral and cellular immune responses to recombinant herpes zoster vaccine in patients with chronic lymphocytic leukemia and monoclonal B cell lymphocytosis

Author

Muchtar, Eli, primary, Koehler, Amber B., additional, Johnson, Michael J., additional, Rabe, Kari G., additional, Ding, Wei, additional, Call, Timothy G., additional, Leis, Jose F., additional, Kenderian, Saad S., additional, Hayman, Suzanne R., additional, Wang, Yucai, additional, Hampel, Paul J., additional, Holets, Matthew A., additional, Darby, Heather C., additional, Slager, Susan L., additional, Kay, Neil E., additional, Miao, Congrong, additional, Canniff, Jennifer, additional, Whitaker, Jennifer A., additional, Levin, Myron J., additional, Schmid, D. Scott, additional, Kennedy, Richard B., additional, Weinberg, Adriana, additional, and Parikh, Sameer A., additional

Published
2021
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34. Response to COVID-19 Vaccination Post-CAR T Therapy in Patients with Non-Hodgkin Lymphoma and Multiple Myeloma

Author

Wiedmeier, Julia E., primary, Iqbal, Madiha, additional, Munoz, Javier, additional, Bezerra, Evandro D., additional, Garcia Robledo, Juan Esteban, additional, Bansal, Radhika, additional, Johnston, Patrick B., additional, Hathcock, Matthew, additional, Larsen, Jeremy T., additional, Bergsagel, P. Leif, additional, Wang, Yucai, additional, Reeder, Craig B., additional, Leis, Jose F., additional, Fonseca, Rafael, additional, Palmer, Jeanne M., additional, Warsame, Rahma M, additional, Kourelis, Taxiarchis, additional, Hayman, Suzanne R., additional, Dingli, David, additional, Kapoor, Prashant, additional, Kumar, Shaji, additional, Durani, Urshila, additional, Villasboas, Jose C., additional, Paludo, Jonas, additional, Bennani, N. Nora, additional, Ansell, Stephen M., additional, Castro, Januario E, additional, Kharfan-Dabaja, Mohamed A., additional, Lin, Yi, additional, Vergidis, Paschalis, additional, Murthy, Hemant S., additional, and Rosenthal, Allison C., additional

Published
2021
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35. Higher Skeletal Muscle Index Is Associated with Improved Overall Survival in Older Patients with Sarcopenia Undergoing Allogeneic Stem Cell Transplant

Author

Gaulin, Charles, primary, Langlais, Blake T., additional, Mountjoy, Luke, additional, Korfiatis, Panagiotis, additional, Tan, Nelly, additional, Leis, Jose F., additional, Khera, Nandita, additional, Noel, Pierre, additional, Sproat, Lisa Z., additional, Jain, Tania, additional, and Palmer, Jeanne M., additional

Published
2021
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36. Outcomes of Patients with Chronic Lymphocytic Leukemia (CLL) Treated with the Combination of Ibrutinib (I) and Venetoclax (V; I+V) after Progression on I Alone (V-naïve) or after Progression on Sequential I and V (Double-Refractory)

Author

Hampel, Paul J., primary, Rabe, Kari G., additional, Call, Timothy G., additional, Ding, Wei, additional, Leis, Jose F., additional, Chanan-Khan, Asher, additional, Kenderian, Saad S., additional, Muchtar, Eli, additional, Wang, Yucai, additional, Ailawadhi, Sikander, additional, Koehler, Amber, additional, Schwager, Susan M., additional, Sher, Taimur, additional, Hanson, Curtis A., additional, Shi, Min, additional, Van Dyke, Daniel L., additional, Braggio, Esteban, additional, Slager, Susan L., additional, Kay, Neil E., additional, and Parikh, Sameer A., additional

Published
2021
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37. Differential prognosis of single and multiple TP53abnormalities in high-count MBL and untreated CLL

Author

Griffin, Rosalie, Wiedmeier-Nutor, Julia E., Parikh, Sameer A., McCabe, Chantal E., O'Brien, Daniel R., Boddicker, Nicholas J., Kleinstern, Geffen, Rabe, Kari G., Bruins, Laura, Brown, Sochilt, Bonolo de Campos, Cecilia, Ding, Wei, Leis, Jose F., Hampel, Paul J., Call, Timothy G., Van Dyke, Daniel L., Kay, Neil E., Cerhan, James R., Yan, Huihuang, Slager, Susan L., and Braggio, Esteban

Abstract

•Similar mutation frequency, type, and location in TP53between 849 patients newly diagnosed with CLL and 381 patients with HCMBL.•Having multiple TP53abnormalities increased the risk of progression to therapy and shortened the overall survival.

Published
2023
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41. Outcomes of Patients with Small Lymphocytic Lymphoma (SLL) Receiving First Line Treatment

Author

Kosydar, Samuel, Rabe, Kari G., Wang, Yucai, Kenderian, Saad S., Ding, Wei, Muchtar, Eli, Leis, Jose F., Koehler, Amber, Tsang, Mazie, Parrondo, Ricardo, Hilal, Talal, Bubik, Rachel, Schwager, Susan Marie, Hanson, Curtis A., Braggio, Esteban, Slager, Susan L., Shi, Min, Van Dyke, Daniel L., Call, Timothy G., Kay, Neil E., Parikh, Sameer A., and Hampel, Paul J

Published
2023
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42. Incidence of Richter Transformation in Patients with Chronic Lymphocytic Leukemia (CLL) /Small Lymphocytic Lymphoma (SLL): A Cohort Study Evaluating Different Therapeutic Eras

Author

Hampel, Paul J., Rabe, Kari G., Wang, Yucai, Hwang, Steven R, Kenderian, Saad S., Muchtar, Eli, Leis, Jose F., Koehler, Amber, Tsang, Mazie, Parrondo, Ricardo, Bubik, Rachel, Schwager, Susan Marie, Hanson, Curtis A., Braggio, Esteban, Slager, Susan L., Shi, Min, Van Dyke, Daniel L., Call, Timothy G., Kay, Neil E., Ding, Wei, and Parikh, Sameer A.

Published
2023
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45. Identification of a Novel Role for PD-1 Signaling in Promotion Tumor Proliferation in B-Cell Lymphoma

Author

Sinha, Sutapa, Ding, Wei, Price-Troska, Tammy, Sakemura, Reona, Tian, Shulan, Secreto, Charla R., Wu, Xiaosheng, Call, Timothy G., He, Rong, Parikh, Sameer A., Wang, Yucai, Leis, Jose F., Yan, Huihuang, Rech, Karen, Koehler, Amber B., Van Dyke, Daniel L., Liu, Minetta C., Slager, Susan L., Braggio, Esteban, Ansell, Stephen M., Kenderian, Saad S., and Kay, Neil E.

Published
2020
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46. Abstract 2209: Characterization of underlying genomic features among African ancestry populations diagnosed with chronic lymphocytic leukemia

Author

de Campos, Cecilia Bonolo, primary, O'Brien, Daniel R., additional, McCabe, Chantal E., additional, Yan, Huihuang, additional, Kleinstern, Geffen, additional, Wang, Zhiquan, additional, Bruins, Laura A., additional, Allmer, Cristine, additional, Boddicker, Nicholas J., additional, Secreto, Charla R., additional, Norman, Aaron D., additional, Tian, Shulan, additional, Rabe, Kari G., additional, Call, Timothy G., additional, Parikh, Sameer A., additional, Leis, Jose F., additional, Ding, Wei, additional, Furman, Richard, additional, Weinberg, J Brice, additional, Cerhan, James R., additional, Vachon, Celine M., additional, Kay, Neil E., additional, Slager, Susan L., additional, and Braggio, Esteban, additional

Published
2021
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47. Abstract 884: Tumor mutational load derived from recurrently mutated genes in chronic lymphocytic leukemia (CLL) predicts time-to-first treatment in high-count monoclonal B-cell lymphocytosis (HC MBL)

Author

Kleinstern, Geffen, primary, de Campos, Cecilia Bonolo, additional, Boddicker, Nicholas J., additional, O'Brien, Daniel R., additional, Tian, Shulan, additional, Barney, Chantel, additional, Rabe, Kari G., additional, Allmer, Cristine, additional, Bruins, Laura, additional, Norman, Aaron D., additional, Call, Timothy G., additional, Parikh, Sameer A., additional, Leis, Jose F., additional, Ding, Wei, additional, Yan, Huihuang, additional, Cerhan, James R., additional, Kay, Neil E., additional, Vachon, Celine, additional, Braggio, Esteban, additional, and Slager, Susan L., additional

Published
2021
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48. Relapse risk in patients with malignant diseases given allogeneic hematopoietic cell transplantation after nonmyeloablative conditioning

Author

Kahl, Christoph, Storer, Barry E., Sandmaier, Brenda M., Mielcarek, Marco, Maris, Michael B., Blume, Karl G., Niederwieser, Dietger, Chauncey, Thomas R., Forman, Stephen J., Agura, Edward, Leis, Jose F., Bruno, Benedetto, Langston, Amelia, Pulsipher, Michael A., McSweeney, Peter A., Wade, James C., Epner, Elliot, Bo Petersen, Finn, Bethge, Wolfgang A., Maloney, David G., and Storb, Rainer

Published
2007
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49. The prognostic significance of del6q23 in chronic lymphocytic leukemia

Author

Audil, Hadiyah Y., primary, Hampel, Paul J., additional, Van Dyke, Daniel L., additional, Achenbach, Sara J., additional, Rabe, Kari G., additional, Smoley, Stephanie A., additional, Call, Timothy G., additional, Ding, Wei, additional, Shi, Min, additional, Hanson, Curtis A., additional, Wang, Yucai, additional, Muchtar, Eli, additional, Koehler, Amber B., additional, Schwager, Susan M., additional, Leis, Jose F., additional, Braggio, Esteban, additional, Slager, Susan L., additional, Kay, Neil E., additional, Kenderian, Saad S., additional, and Parikh, Sameer A., additional

Published
2021
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50. Use of Artificial Intelligence Electrocardiography to Predict Atrial Fibrillation (AF) in Patients with Chronic Lymphocytic Leukemia (CLL)

Author

Christopoulos, Georgios, primary, Attia, Zachi I., additional, Noseworthy, Peter A., additional, Call, Timothy G., additional, Ding, Wei, additional, Leis, Jose F., additional, Muchtar, Eli, additional, Kenderian, Saad S., additional, Wang, Yucai, additional, Koehler, Amber, additional, Kay, Neil E., additional, Kapoor, Prashant, additional, Friedman, Paul A., additional, Herrmann, Joerg, additional, and Parikh, Sameer A., additional

Published
2020
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