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1. Advanced capabilities for materials modelling with Quantum ESPRESSO

Author

Giannozzi, P., Andreussi, O., Brumme, T., Bunau, O., Nardelli, M. Buongiorno, Calandra, M., Car, R., Cavazzoni, C., Ceresoli, D., Cococcioni, M., Colonna, N., Carnimeo, I., Corso, A. Dal, de Gironcoli, S., Delugas, P., DiStasio Jr., R. A., Ferretti, A., Floris, A., Fratesi, G., Fugallo, G., Gebauer, R., Gerstmann, U., Giustino, F., Gorni, T., Jia, J., Kawamura, M., Ko, H. -Y., Kokalj, A., Küçükbenli, E., Lazzeri, M., Marsili, M., Marzari, N., Mauri, F., Nguyen, N. L., Nguyen, H. -V., Otero-de-la-Roza, A., Paulatto, L., Poncé, S., Rocca, D., Sabatini, R., Santra, B., Schlipf, M., Seitsonen, A. P., Smogunov, A., Timrov, I., Thonhauser, T., Umari, P., Vast, N., Wu, X., and Baroni, S.

Subjects
Condensed Matter - Materials Science
Abstract

Quantum ESPRESSO is an integrated suite of open-source computer codes for quantum simulations of materials using state-of-the art electronic-structure techniques, based on density-functional theory, density-functional perturbation theory, and many-body perturbation theory, within the plane-wave pseudo-potential and projector-augmented-wave approaches. Quantum ESPRESSO owes its popularity to the wide variety of properties and processes it allows to simulate, to its performance on an increasingly broad array of hardware architectures, and to a community of researchers that rely on its capabilities as a core open-source development platform to implement theirs ideas. In this paper we describe recent extensions and improvements, covering new methodologies and property calculators, improved parallelization, code modularization, and extended interoperability both within the distribution and with external software., Comment: Psi-k highlight September 2017: psi-k.net/dowlnload/highlights/Highlight_137.pdf; J. Phys.: Condens. Matter, accepted

Published
2017
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2. Temperature evolution of infrared- and Raman-active phonons in graphite

Author

Giura, P., Bonini, N., Creff, G., Brubach, J. B., Roy, P., and Lazzeri, M.

Subjects
Condensed Matter - Materials Science
Abstract

We perform a comparative experimental and theoretical study of the temperature dependence up to 700 K of the frequency and linewidths of the graphite E1u and E2g optical phonons (~1590 and 1580 cm-1) by infra-red (IR) and Raman spectroscopy. Despite their similar character, the temperature dependence of the two modes is quite different, being, e.g., the frequency shift of the IR-active E1u mode is almost twice as big as that of the Raman active E2g mode. Ab initio calculations of the anharmonic properties are in remarkable agreement with measurements and explain the observed behavior., Comment: 5 pages, 4 figures

Published
2012
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3. Quantum ESPRESSO: a modular and open-source software project for quantum simulations of materials

Author

Giannozzi, P., Baroni, S., Bonini, N., Calandra, M., Car, R., Cavazzoni, C., Ceresoli, D., Chiarotti, G. L., Cococcioni, m., Dabo, I., Corso, A. Dal, Fabris, S., Fratesi, G., de Gironcoli, S., Gebauer, R., Gerstmann, U., Gougoussis, C., Kokalj, A., Lazzeri, M., Martin-Samos, L., Marzari, N., Mauri, F., Mazzarello, R., Paolini, S., Pasquarello, A., Paulatto, L., Sbraccia, C., Scandolo, S., Sclauzero, G., Seitsonen, A. P., Smogunov, A., Umari, P., and Wentzcovitch, R. M.

Subjects
Condensed Matter - Materials Science
Abstract

Quantum ESPRESSO is an integrated suite of computer codes for electronic-structure calculations and materials modeling, based on density-functional theory, plane waves, and pseudopotentials (norm-conserving, ultrasoft, and projector-augmented wave). Quantum ESPRESSO stands for "opEn Source Package for Research in Electronic Structure, Simulation, and Optimization". It is freely available to researchers around the world under the terms of the GNU General Public License. Quantum ESPRESSO builds upon newly-restructured electronic-structure codes that have been developed and tested by some of the original authors of novel electronic-structure algorithms and applied in the last twenty years by some of the leading materials modeling groups worldwide. Innovation and efficiency are still its main focus, with special attention paid to massively-parallel architectures, and a great effort being devoted to user friendliness. Quantum ESPRESSO is evolving towards a distribution of independent and inter-operable codes in the spirit of an open-source project, where researchers active in the field of electronic-structure calculations are encouraged to participate in the project by contributing their own codes or by implementing their own ideas into existing codes., Comment: 36 pages, 5 figures, resubmitted to J.Phys.: Condens. Matter

Published
2009
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4. Phonon surface mapping of graphite: disentangling quasi--degenerate phonon dispersions

Author

Grüneis, A., Serrano, J., Bosak, A., Lazzeri, M., Molodtsov, S. L., Wirtz, L., Attaccalite, C., Krisch, M., Rubio, A., Mauri, F., and Pichler, T.

Subjects
Condensed Matter - Strongly Correlated Electrons
Abstract

The two-dimensional mapping of the phonon dispersions around the $K$ point of graphite by inelastic x-ray scattering is provided. The present work resolves the longstanding issue related to the correct assignment of transverse and longitudinal phonon branches at $K$. We observe an almost degeneracy of the three TO, LA and LO derived phonon branches and a strong phonon trigonal warping. Correlation effects renormalize the Kohn anomaly of the TO mode, which exhibits a trigonal warping effect opposite to that of the electronic band structure. We determined the electron--phonon coupling constant to be 166$\rm(eV/\AA)^2$ in excellent agreement to $GW$ calculations. These results are fundamental for understanding angle-resolved photoemission, double--resonance Raman and transport measurements of graphene based systems.

Published
2009
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5. Multi-imaging model for local staging and targeted treatment of localized prostate cancer using high-intensity focused ultrasound (HIFU) focal therapy

Author

Maffei, D., primary, Fasulo, V., additional, Moretto, S., additional, Adjaye, E.N.Y.D., additional, Paciotti, M., additional, Avolio, P.P., additional, De Carne, F., additional, Arena, P., additional, Lopci, E., additional, Colombo, P.G., additional, Balzarini, L., additional, Saita, A.R., additional, Hurle, R., additional, Guazzoni, G.F., additional, Buffi, N., additional, Casale, P., additional, Lazzeri, M., additional, and Lughezzani, G., additional

Published
2023
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6. The predictive role of left ventricular cathode topography relative to CMR-determined latest mechanical activation and scar segments on response to cardiac resynchronisation therapy

Author

Bertelli, M, primary, Van Slochteren, F J, additional, Rondanina, E, additional, Lazzeri, M, additional, Carecci, A, additional, Quaranta, A, additional, Angeletti, A, additional, Spadotto, A, additional, Massaro, G, additional, Frisoni, J, additional, Diemberger, I, additional, Martignani, C, additional, Galie', N, additional, Biffi, M, additional, and Ziacchi, M, additional

Published
2023
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7. Cassandra speaks: a case series of unanticipated subcutaneous ICD premature battery depletion in a single-centre experience

Author

Lazzeri, M, primary, Carecci, A, additional, Bertelli, M, additional, Quaranta, A, additional, Spadotto, A, additional, Bartoli, L, additional, Massaro, G, additional, Angeletti, A, additional, Frisoni, J, additional, Valzania, C, additional, Diemberger, I, additional, Martignani, C, additional, Ziacchi, M, additional, Galie', N, additional, and Biffi, M, additional

Published
2023
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8. Lead placement in extravascular ICD recipients: the first step to prevent P-wave oversensing

Author

Quaranta, A, primary, Carecci, A, additional, Lazzeri, M, additional, Bertelli, M, additional, Angeletti, A, additional, Spadotto, A, additional, Massaro, G, additional, Bartoli, L, additional, Frisoni, J, additional, Valzania, C, additional, Diemberger, I, additional, Martignani, C, additional, Ziacchi, M, additional, Galie', N, additional, and Biffi, M, additional

Published
2023
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9. Is multiparametric MRI always needed in biopsy-naïve patients with abnormal digital rectal examination? A single-institutional experience combining clinical and micro-ultrasonography based factors to optimize prostate cancer detection.

Author

Avolio, P.P., primary, Maffei, D., additional, Fasulo, V., additional, Paciotti, M., additional, Saitta, C., additional, De Carne, F., additional, Buffi, N.M., additional, Lazzeri, M., additional, and Lughezzani, G., additional

Published
2023
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11. Intermuscular placement and defibrillation with the extravascular ICD: a single-centre experience

Author

Carecci, A, primary, Lazzeri, M, additional, Quaranta, A, additional, Bertelli, M, additional, Spadotto, A, additional, Angeletti, A, additional, Massaro, G, additional, Bartoli, L, additional, Frisoni, J, additional, Martignani, C, additional, Valzania, C, additional, Diemberger, I, additional, Ziacchi, M, additional, Galie', N, additional, and Biffi, M, additional

Published
2023
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12. Electron Transport and Hot Phonons in Carbon Nanotubes

Author

Lazzeri, M., Piscanec, S., Mauri, F., Ferrari, A. C., and Robertson, J.

Subjects
Condensed Matter - Materials Science
Abstract

We demonstrate the key role of phonon occupation in limiting the high-field ballistic transport in metallic carbon nanotubes. In particular, we provide a simple analytic formula for the electron transport scattering length, that we validate by accurate first principles calculations on (6,6) and (11,11) nanotubes. The comparison of our results with the scattering lengths fitted from experimental I-V curves indicates the presence of a non-equilibrium optical phonon heating induced by electron transport. We predict an effective temperature for optical phonons of thousands Kelvin., Comment: 4 pages, 1 figure

Published
2005
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13. Kohn Anomalies and Electron-Phonon Interaction in Graphite

Author

Piscanec, S., Lazzeri, M., Mauri, F., Ferrari, A. C., and Robertson, J.

Subjects
Condensed Matter - Materials Science
Abstract

We demonstrate that graphite phonon dispersions have two Kohn anomalies at the Gamma-E_2g and K-A'1 modes. The anomalies are revealed by two sharp kinks. By an exact analytic derivation, we show that the slope of these kinks is proportional to the square of the electron-phonon coupling (EPC). Thus, we can directly measure the EPC from the experimental dispersions. The Gamma-E_2g and K-A'1 EPCs are particularly large, whilst they are negligible for all the other modes at Gamma and K., Comment: 4 pages, 2 figures

Published
2004
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14. The last shall be the first: the role of combined QLV- and CMR-determined electromechanical concordance in predicting optimal left ventricular stimulation site in cardiac resynchronisation therapy

Author

Bertelli, M, primary, Ziacchi, M, additional, Van Slochteren, F J, additional, Rondanina, E, additional, Martignani, C, additional, Angeletti, A, additional, Massaro, G, additional, Spadotto, A, additional, Lazzeri, M, additional, Carecci, A, additional, Diemberger, I, additional, and Biffi, M, additional

Published
2023
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20. The role of Mayo Adhesive Probability score in operative outcomes: A single center prospective analysis

Author

Garofano, G., primary, Diana, P., additional, Saitta, C., additional, Uleri, A., additional, Lughezzani, G., additional, Beatrici, E., additional, Chiarelli, G., additional, Frego, N., additional, Contieri, R., additional, Paciotti, M., additional, Fasulo, V., additional, Lazzeri, M., additional, Saita, A., additional, Hurle, R., additional, Casale, P., additional, Guazzoni, G., additional, and Buffi, N., additional

Published
2022
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22. Early oncological outcomes of a novel high-intensity focused ultrasound focal therapy program using a multi-imaging model for local and systemic staging of prostate cancer

Author

Maffei, D., primary, Fasulo, V., additional, Adjaye, E.N.A., additional, Diana, P., additional, Saitta, C., additional, Uleri, A., additional, Lazzeri, M., additional, Hurle, R., additional, Guazzoni, G.F., additional, Casale, P., additional, Buffi, N.M., additional, and Lughezzani, G., additional

Published
2022
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23. Development of BIFECTA: A surgical success score for percutaneous microwave ablation of renal masses and validation of PADUA, SPARE and R.E.N.A.L. nephrometry scores

Author

Uleri, A., primary, Beatrici, E., additional, Diana, P., additional, Lughezzani, G., additional, Casale, P., additional, Garofano, G., additional, Avolio, P.P., additional, Saitta, C., additional, Lazzeri, M., additional, Lanza, E., additional, Poretti, D., additional, Pedicini, V., additional, and Buffi, N., additional

Published
2022
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24. Adherent perinephric fat as predictor of post-operative functional recovery after robot-assisted partial nephrectomy

Author

Diana, P., primary, Garofano, G., additional, Uleri, A., additional, Lughezzani, G., additional, Beatrici, E., additional, Saitta, C., additional, Chiarelli, G., additional, Frego, N., additional, Paciotti, M., additional, Fasulo, V., additional, Lazzeri, M., additional, Saita, A., additional, Hurle, R., additional, Casale, P., additional, Guazzoni, G., additional, and Buffi, N., additional

Published
2022
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25. Renal cell carcinoma with venous thrombus: A retrospective single center surgical and oncological analysis

Author

Saitta, C., primary, Diana, P., additional, Lughezzani, G., additional, Casale, P., additional, Uleri, A., additional, Beatrici, E., additional, Chiarelli, G., additional, Garofano, G., additional, Fasulo, V., additional, Avolio, P.P., additional, Lazzeri, M., additional, Hurle, R., additional, Saita, A., additional, Giorgio, G., additional, and Buffi, N., additional

Published
2022
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27. Assessing the detrimental effect of the covid-19 pandemic on the outcomes of robot-assisted radical prostatectomy. A single-institutional analysis

Author

Avolio, P.P., primary, Fasuolo, V., additional, Paciotti, M., additional, Maffei, D., additional, Frego, N., additional, Diana, P., additional, Uleri, A., additional, Contieri, R., additional, Saitta, C., additional, Arena, P., additional, Chiarelli, G., additional, Garofano, G., additional, De Carne, F., additional, Casale, P., additional, Saita, A., additional, Lazzeri, M., additional, Hurle, R., additional, Lughezzani, G., additional, and Buffi, N.M., additional

Published
2022
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28. [18F]-FDG PET/CT for bladder cancer staging and decision-making in patients with high-risk non-muscle invasive bladder cancer (HR-NMIBC)

Author

Hurle, R., primary, Contieri, R., additional, Gobbo, A., additional, Frego, N., additional, Uleri, A., additional, Avolio, P.P., additional, Mancon, S., additional, Saita, A., additional, Chiti, A., additional, Rodari, M., additional, Sollini, M., additional, Pini, C., additional, Gelardi, F., additional, Fasulo, V., additional, Paciotti, M., additional, Lughezzani, G., additional, Buffi, N.M., additional, Guazzoni, G., additional, Casale, P., additional, and Lazzeri, M., additional

Published
2022
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29. Diagnostic performance of micro-ultrasound guided reclassification biopsies in patients under active surveillance for prostate cancer

Author

Maffei, D., primary, Saitta, C., additional, Avolio, P.P., additional, Fasulo, V., additional, Paciotti, M., additional, Frego, N., additional, Diana, P., additional, Lazzeri, M., additional, Hurle, R., additional, Saita, A., additional, Guazzoni, G.F., additional, Casale, P., additional, Buffi, N.M., additional, and Lughezzani, G., additional

Published
2022
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30. Accuracy of AUA and EAU risk stratification groups in predicting early recurrence in HG TA non-muscle invasive bladder cancer: a comparison analysis

Author

Contieri, R., primary, Gobbo, A., additional, Paciotti, M., additional, Avolio, P.P., additional, Fasulo, V., additional, Saitta, C., additional, Uleri, A., additional, Valeri, M., additional, Colombo, P., additional, Saita, A., additional, Lazzeri, M., additional, Lughezzani, G., additional, Buffi, N.M., additional, Casale, P., additional, Guazzoni, G., additional, and Hurle, R., additional

Published
2022
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31. Assessing the role of high-resolution micro-ultrasound among patients with a negative multiparametric MRI and persistent suspicion of prostate cancer

Author

Avolio, P.P., primary, Fasuolo, V., additional, Paciotti, M., additional, Diana, P., additional, Frego, N., additional, Maffei, D., additional, Contieri, R., additional, Uleri, A., additional, Saitta, C., additional, Beatrici, E., additional, Chiarelli, G., additional, De Carne, F., additional, Hurle, R., additional, Lazzeri, M., additional, Saita, A., additional, Casale, P., additional, Buffi, N.M., additional, and Lughezzani, G., additional

Published
2022
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32. Developing of a novel nephrometry score to predict the outcomes of percutaneous ablation of renal masses

Author

Sordelli, F., primary, Uleri, A., additional, Diana, P., additional, Beatrici, E., additional, Saitta, C., additional, Lughezzani, G., additional, Lazzeri, M., additional, Casale, P., additional, Pedicini, V., additional, Hurle, R., additional, Saita, A., additional, Arena, P., additional, Frego, N., additional, Poretti, D., additional, and Buffi, N., additional

Published
2022
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34. The update from bladder cancer italian active surveillance (BIAS) project for low-grade bladder tumors: long-term oncological outcomes of patients under active surveillance

Author

Beatrici, E., primary, Contieri, R., additional, Frego, N., additional, Fasulo, V., additional, Diana, P., additional, Paciotti, M., additional, Saitta, C., additional, Chiarelli, G., additional, Arena, P., additional, Gobbo, A., additional, Avolio, P.P., additional, Uleri, A., additional, Buffi, N.M., additional, Lazzeri, M., additional, Casale, P., additional, Saita, A., additional, Guazzoni, G., additional, Lughezzani, G., additional, and Hurle, R., additional

Published
2022
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36. Is testis sparing surgery safe in patients with incidental small testicular lesions referring to a fertility center? a retrospective analysis reporting factors correlated to malignancy and long-term oncological outcomes

Author

Gobbo, A., primary, Fasulo, V., additional, Saitta, C., additional, Benaglia, R., additional, Lughezzani, G., additional, Saita, A., additional, Guazzoni, G.F., additional, Hurle, R., additional, Lazzeri, M., additional, Contieri, R., additional, Casale, P., additional, Setti, P. Levi, additional, Chiarelli, G., additional, Buffi, N.M., additional, and Negri, L., additional

Published
2022
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37. Is less always more? A prospective two-centre study addressing clinical outcomes in leadless versus transvenous single-chamber pacemaker recipients

Author

Bertelli, M, primary, Toniolo, S, additional, Gasperetti, A, additional, Schiavone, M, additional, Arosio, R, additional, Statuto, G, additional, Ziacchi, M, additional, Mitacchione, G, additional, Angeletti, A, additional, Spadotto, A, additional, Bartoli, L, additional, Lazzeri, M, additional, Carecci, A, additional, Forleo, G B, additional, and Biffi, M, additional

Published
2022
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39. The relationship between adherent perinephric fat and the mayo adhesive probability (MAP) score and post-operative functional outcomes in patients subjected to robot-assisted partial nephrectomy

Author

Garofano, G., primary, Diana, P., additional, Uleri, A., additional, Lughezzani, G., additional, Beatrici, E., additional, Saitta, C., additional, Frego, N., additional, Paciotti, M., additional, Contieri, R., additional, Lazzeri, M., additional, Saita, A., additional, Hurle, R., additional, Guazzoni, G., additional, and Buffi, N..M., additional

Published
2022
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40. Percutaneous microwave ablation may represent an effective treatment in selected patients with clinical T1 renal masses: a single-institutional experience

Author

Beatrici, E., primary, Uleri, A., additional, Diana, P., additional, Saitta, C., additional, Chiarelli, G., additional, Arena, P., additional, Gobbo, A., additional, Fasulo, V., additional, Avolio, P.P., additional, D’Antuono, F., additional, Poretti, D., additional, Pedicini, V., additional, Lazzeri, M., additional, Saita, A., additional, Hurle, R., additional, Lughezzani, G., additional, Guazzoni, G., additional, and Buffi, N.M., additional

Published
2022
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41. Sigh in patients with acute hypoxemic respiratory failure and acute respiratory distress syndrome: the PROTECTION pilot randomized clinical trial

Author

Mauri, T, Foti, G, Fornari, C, Grasselli, G, Pinciroli, R, Lovisari, F, Tubiolo, D, Volta, C, Spadaro, S, Rona, R, Rondelli, E, Navalesi, P, Garofalo, E, Knafelj, R, Gorjup, V, Colombo, R, Cortegiani, A, Zhou, J, D'Andrea, R, Calamai, I, Gonzalez, A, Roca, O, Grieco, D, Jovaisa, T, Bampalis, D, Becher, T, Battaglini, D, Ge, H, Luz, M, Constantin, J, Ranieri, M, Guerin, C, Mancebo, J, Pelosi, P, Fumagalli, R, Brochard, L, Pesenti, A, Papoff, A, Di Fenza, R, Gianni, S, Spinelli, E, Lissoni, A, Abbruzzese, C, Bronco, A, Villa, S, Russotto, V, Iachi, A, Ball, L, Patroniti, N, Spina, R, Giuntini, R, Peruzzi, S, Menga, L, Fossali, T, Castelli, A, Ottolina, D, Garcia-De-Acilu, M, Santafe, M, Schadler, D, Weiler, N, Carvajal, E, Calvo, C, Neou, E, Wang, Y, Zhou, Y, Longhini, F, Bruni, A, Leonardi, M, Gregoretti, C, Ippolito, M, Milazzo, Z, Querci, L, Ranieri, S, Insom, G, Berden, J, Noc, M, Mikuz, U, Arzenton, M, Lazzeri, M, Villa, A, Barreto, B, Rios, M, Gusmao-Flores, D, Phull, M, Barnes, T, Musarat, H, Conti, S, Mauri T., Foti G., Fornari C., Grasselli G., Pinciroli R., Lovisari F., Tubiolo D., Volta C. A., Spadaro S., Rona R., Rondelli E., Navalesi P., Garofalo E., Knafelj R., Gorjup V., Colombo R., Cortegiani A., Zhou J. -X., D'Andrea R., Calamai I., Gonzalez A. V., Roca O., Grieco D. L., Jovaisa T., Bampalis D., Becher T., Battaglini D., Ge H., Luz M., Constantin J. -M., Ranieri M., Guerin C., Mancebo J., Pelosi P., Fumagalli R., Brochard L., Pesenti A., Papoff A., Di Fenza R., Gianni S., Spinelli E., Lissoni A., Abbruzzese C., Bronco A., Villa S., Russotto V., Iachi A., Ball L., Patroniti N., Spina R., Giuntini R., Peruzzi S., Menga L. S., Fossali T., Castelli A., Ottolina D., Garcia-De-Acilu M., Santafe M., Schadler D., Weiler N., Carvajal E. R., Calvo C. P., Neou E., Wang Y. -M., Zhou Y. -M., Longhini F., Bruni A., Leonardi M., Gregoretti C., Ippolito M., Milazzo Z., Querci L., Ranieri S., Insom G., Berden J., Noc M., Mikuz U., Arzenton M., Lazzeri M., Villa A., Barreto B. B., Rios M. N. O., Gusmao-Flores D., Phull M., Barnes T., Musarat H., Conti S., Mauri, T, Foti, G, Fornari, C, Grasselli, G, Pinciroli, R, Lovisari, F, Tubiolo, D, Volta, C, Spadaro, S, Rona, R, Rondelli, E, Navalesi, P, Garofalo, E, Knafelj, R, Gorjup, V, Colombo, R, Cortegiani, A, Zhou, J, D'Andrea, R, Calamai, I, Gonzalez, A, Roca, O, Grieco, D, Jovaisa, T, Bampalis, D, Becher, T, Battaglini, D, Ge, H, Luz, M, Constantin, J, Ranieri, M, Guerin, C, Mancebo, J, Pelosi, P, Fumagalli, R, Brochard, L, Pesenti, A, Papoff, A, Di Fenza, R, Gianni, S, Spinelli, E, Lissoni, A, Abbruzzese, C, Bronco, A, Villa, S, Russotto, V, Iachi, A, Ball, L, Patroniti, N, Spina, R, Giuntini, R, Peruzzi, S, Menga, L, Fossali, T, Castelli, A, Ottolina, D, Garcia-De-Acilu, M, Santafe, M, Schadler, D, Weiler, N, Carvajal, E, Calvo, C, Neou, E, Wang, Y, Zhou, Y, Longhini, F, Bruni, A, Leonardi, M, Gregoretti, C, Ippolito, M, Milazzo, Z, Querci, L, Ranieri, S, Insom, G, Berden, J, Noc, M, Mikuz, U, Arzenton, M, Lazzeri, M, Villa, A, Barreto, B, Rios, M, Gusmao-Flores, D, Phull, M, Barnes, T, Musarat, H, Conti, S, Mauri T., Foti G., Fornari C., Grasselli G., Pinciroli R., Lovisari F., Tubiolo D., Volta C. A., Spadaro S., Rona R., Rondelli E., Navalesi P., Garofalo E., Knafelj R., Gorjup V., Colombo R., Cortegiani A., Zhou J. -X., D'Andrea R., Calamai I., Gonzalez A. V., Roca O., Grieco D. L., Jovaisa T., Bampalis D., Becher T., Battaglini D., Ge H., Luz M., Constantin J. -M., Ranieri M., Guerin C., Mancebo J., Pelosi P., Fumagalli R., Brochard L., Pesenti A., Papoff A., Di Fenza R., Gianni S., Spinelli E., Lissoni A., Abbruzzese C., Bronco A., Villa S., Russotto V., Iachi A., Ball L., Patroniti N., Spina R., Giuntini R., Peruzzi S., Menga L. S., Fossali T., Castelli A., Ottolina D., Garcia-De-Acilu M., Santafe M., Schadler D., Weiler N., Carvajal E. R., Calvo C. P., Neou E., Wang Y. -M., Zhou Y. -M., Longhini F., Bruni A., Leonardi M., Gregoretti C., Ippolito M., Milazzo Z., Querci L., Ranieri S., Insom G., Berden J., Noc M., Mikuz U., Arzenton M., Lazzeri M., Villa A., Barreto B. B., Rios M. N. O., Gusmao-Flores D., Phull M., Barnes T., Musarat H., and Conti S.

Abstract

Background: Sigh is a cyclic brief recruitment maneuver: previous physiologic studies showed that its use could be an interesting addition to pressure support ventilation to improve lung elastance, decrease regional heterogeneity, and increase release of surfactant. Research Question: Is the clinical application of sigh during pressure support ventilation (PSV) feasible? Study Design and Methods: We conducted a multicenter noninferiority randomized clinical trial on adult intubated patients with acute hypoxemic respiratory failure or ARDS undergoing PSV. Patients were randomized to the no-sigh group and treated by PSV alone, or to the sigh group, treated by PSV plus sigh (increase in airway pressure to 30 cm H2O for 3 s once per minute) until day 28 or death or successful spontaneous breathing trial. The primary end point of the study was feasibility, assessed as noninferiority (5% tolerance) in the proportion of patients failing assisted ventilation. Secondary outcomes included safety, physiologic parameters in the first week from randomization, 28-day mortality, and ventilator-free days. Results: Two-hundred and fifty-eight patients (31% women; median age, 65 [54-75] years) were enrolled. In the sigh group, 23% of patients failed to remain on assisted ventilation vs 30% in the no-sigh group (absolute difference, –7%; 95% CI, –18% to 4%; P =. 015 for noninferiority). Adverse events occurred in 12% vs 13% in the sigh vs no-sigh group (P =. 852). Oxygenation was improved whereas tidal volume, respiratory rate, and corrected minute ventilation were lower over the first 7 days from randomization in the sigh vs no-sigh group. There was no significant difference in terms of mortality (16% vs 21%; P =. 337) and ventilator-free days (22 [7-26] vs 22 [3-25] days; P =. 300) for the sigh vs no-sigh group. Interpretation: Among hypoxemic intubated ICU patients, application of sigh was feasible and without increased risk.

Published
2021

42. Dynamic bedside assessment of the physiologic effects of prone position in acute respiratory distress syndrome patients by electrical impedance tomography

Author

Dalla Corte, F, Mauri, T, Spinelli, E, Lazzeri, M, Turrini, C, Albanese, M, Abbruzzese, C, Lissoni, A, Galazzi, A, Eronia, N, Bronco, A, Maffezzini, E, Pesenti, A, Foti, G, Bellani, G, Grasselli, G, Dalla Corte F., Mauri T., Spinelli E., Lazzeri M., Turrini C., Albanese M., Abbruzzese C., Lissoni A., Galazzi A., Eronia N., Bronco A., Maffezzini E., Pesenti A., Foti G., Bellani G., Grasselli G., Dalla Corte, F, Mauri, T, Spinelli, E, Lazzeri, M, Turrini, C, Albanese, M, Abbruzzese, C, Lissoni, A, Galazzi, A, Eronia, N, Bronco, A, Maffezzini, E, Pesenti, A, Foti, G, Bellani, G, Grasselli, G, Dalla Corte F., Mauri T., Spinelli E., Lazzeri M., Turrini C., Albanese M., Abbruzzese C., Lissoni A., Galazzi A., Eronia N., Bronco A., Maffezzini E., Pesenti A., Foti G., Bellani G., and Grasselli G.

Abstract

BACKGROUND: Prone position (PP) improves acute respiratory distress syndrome (ARDS) survival by reducing the risk of ventilation-induced lung injury. However, inter-individual variability is a hallmark of ARDS and lung protection by PP might not be optimal in all patients. In the present study, we dynamically assessed physiologic effects of PP by electrical impedance tomography (EIT) and identified predictors of improved lung protection by PP in ARDS patients. METHODS: Prospective physiologic study on 16 intubated, sedated and paralyzed patients with ARDS undergoing PP as per clinical decision. EIT data were recorded during two consecutive steps: 1) baseline supine position before and after a recruitment maneuver (RM); 2) prone position before and after a RM. “Improved lung protection” by PP was defined in the presence of simultaneous improvement of ventilation homogeneity (Hom), alveolar overdistension and collapse (ODCL) and amount of recruitable lung volume by RM in comparison to supine. RESULTS: PP versus supine increased the tidal volume distending the dependent regions (Vtdep), resulting in improved Hom (1.1±0.9 vs. 1.7±0.9, P=0.021). PP also reduced ODCL (19±9% vs. 28±8%, P=0.005) and increased the recruitable lung volume (80 [71-157] vs. 59 [1-110] mL, P=0.025). “Improved lung protection” by PP was predicted by lower Vtdep, higher Vtndep and poorer Hom measured during baseline supine position (P<0.05). CONCLUSIONS: EIT enables dynamic bedside assessment of the physiologic effects of PP and might support early recognition of ARDS patients more likely to benefit from PP.

Published
2020

43. Exciton and Phonon Radiative Linewidths in Monolayer Boron Nitride

Author

Cassabois, G., primary, Fugallo, G., additional, Elias, C., additional, Valvin, P., additional, Rousseau, A., additional, Gil, B., additional, Summerfield, A., additional, Mellor, C. J., additional, Cheng, T. S., additional, Eaves, L., additional, Foxon, C. T., additional, Beton, P. H., additional, Lazzeri, M., additional, Segura, A., additional, and Novikov, S. V., additional

Published
2022
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44. Sigh in patients with acute hypoxemic respiratory failure and acute respiratory distress syndrome: the PROTECTION pilot randomized clinical trial

Author

Mauri T., Foti G., Fornari C., Grasselli G., Pinciroli R., Lovisari F., Tubiolo D., Volta C. A., Spadaro S., Rona R., Rondelli E., Navalesi P., Garofalo E., Knafelj R., Gorjup V., Colombo R., Cortegiani A., Zhou J. -X., D'Andrea R., Calamai I., Gonzalez A. V., Roca O., Grieco D. L., Jovaisa T., Bampalis D., Becher T., Battaglini D., Ge H., Luz M., Constantin J. -M., Ranieri M., Guerin C., Mancebo J., Pelosi P., Fumagalli R., Brochard L., Pesenti A., Papoff A., Di Fenza R., Gianni S., Spinelli E., Lissoni A., Abbruzzese C., Bronco A., Villa S., Russotto V., Iachi A., Ball L., Patroniti N., Spina R., Giuntini R., Peruzzi S., Menga L. S., Fossali T., Castelli A., Ottolina D., Garcia-De-Acilu M., Santafe M., Schadler D., Weiler N., Carvajal E. R., Calvo C. P., Neou E., Wang Y. -M., Zhou Y. -M., Longhini F., Bruni A., Leonardi M., Gregoretti C., Ippolito M., Milazzo Z., Querci L., Ranieri S., Insom G., Berden J., Noc M., Mikuz U., Arzenton M., Lazzeri M., Villa A., Barreto B. B., Rios M. N. O., Gusmao-Flores D., Phull M., Barnes T., Musarat H., Conti S., Mauri, Tommaso, Foti, Giuseppe, Fornari, Carla, Grasselli, Giacomo, Pinciroli, Riccardo, Lovisari, Federica, Tubiolo, Daniela, Volta, Carlo Alberto, Spadaro, Savino, Rona, Roberto, Rondelli, Egle, Navalesi, Paolo, Garofalo, Eugenio, Knafelj, Rihard, Gorjup, Vojka, Colombo, Riccardo, Cortegiani, Andrea, Zhou, Jian-Xin, D'Andrea, Rocco, Calamai, Italo, González, Ánxela Vidal, Roca, Oriol, Grieco, Domenico Luca, Jovaisa, Toma, Bampalis, Dimitrio, Becher, Tobia, Battaglini, Denise, Ge, Huiqing, Luz, Mariana, Constantin, Jean-Michel, Ranieri, Marco, Guerin, Claude, Mancebo, Jordi, Pelosi, Paolo, Fumagalli, Roberto, Brochard, Laurent, Pesenti, Antonio, PROTECTION collaborators: Alessandra Papoff, Raffaele Di Fenza, Stefano Gianni, Elena Spinelli, Alfredo Lissoni, Chiara Abbruzzese, Alfio Bronco, Silvia Villa, Vincenzo Russotto, Arianna Iachi, Lorenzo Ball, Nicolò Patroniti, Rosario Spina, Romano Giuntini, Simone Peruzzi, Luca Salvatore Menga, Tommaso Fossali, Antonio Castelli, Davide Ottolina, Marina García-de-Acilu, Manel Santafè, Dirk Schädler, Norbert Weiler, Emilia Rosas Carvajal, César Pérez Calvo, Evangelia Neou, Yu-Mei Wang, Yi-Min Zhou, Federico Longhini, Andrea Bruni, Mariacristina Leonardi, Cesare Gregoretti, Mariachiara Ippolito, Zelia Milazzo, Lorenzo Querci, Serena Ranieri, Giulia Insom, Jernej Berden, Marko Noc, Ursa Mikuz, Matteo Arzenton, Marta Lazzeri, Arianna Villa, Bruna Brandão Barreto, Marcos Nogueira Oliveira Rios, Dimitri Gusmao-Flores, Mandeep Phull, Tom Barnes, Hussain Musarat, Sara Conti, Mauri, T, Foti, G, Fornari, C, Grasselli, G, Pinciroli, R, Lovisari, F, Tubiolo, D, Volta, C, Spadaro, S, Rona, R, Rondelli, E, Navalesi, P, Garofalo, E, Knafelj, R, Gorjup, V, Colombo, R, Cortegiani, A, Zhou, J, D'Andrea, R, Calamai, I, Gonzalez, A, Roca, O, Grieco, D, Jovaisa, T, Bampalis, D, Becher, T, Battaglini, D, Ge, H, Luz, M, Constantin, J, Ranieri, M, Guerin, C, Mancebo, J, Pelosi, P, Fumagalli, R, Brochard, L, Pesenti, A, Papoff, A, Di Fenza, R, Gianni, S, Spinelli, E, Lissoni, A, Abbruzzese, C, Bronco, A, Villa, S, Russotto, V, Iachi, A, Ball, L, Patroniti, N, Spina, R, Giuntini, R, Peruzzi, S, Menga, L, Fossali, T, Castelli, A, Ottolina, D, Garcia-De-Acilu, M, Santafe, M, Schadler, D, Weiler, N, Carvajal, E, Calvo, C, Neou, E, Wang, Y, Zhou, Y, Longhini, F, Bruni, A, Leonardi, M, Gregoretti, C, Ippolito, M, Milazzo, Z, Querci, L, Ranieri, S, Insom, G, Berden, J, Noc, M, Mikuz, U, Arzenton, M, Lazzeri, M, Villa, A, Barreto, B, Rios, M, Gusmao-Flores, D, Phull, M, Barnes, T, Musarat, H, and Conti, S

Subjects
pressure support, ventilation, sigh, ARDS, mechanical ventilation, feasibility
Abstract

Background: Sigh is a cyclic brief recruitment manoeuvre: previous physiological studies showed that its use could be an interesting addition to pressure support ventilation to improve lung elastance, decrease regional heterogeneity and increase release of surfactant. Research question: Is the clinical application of sigh during pressure support ventilation (PSV) feasible? Study design and methods: We conducted a multi-center non-inferiority randomized clinical trial on adult intubated patients with acute hypoxemic respiratory failure or acute respiratory distress syndrome undergoing PSV. Patients were randomized to the No Sigh group and treated by PSV alone, or to the Sigh group, treated by PSV plus sigh (increase of airway pressure to 30 cmH2Ofor 3 seconds once per minute) until day 28 or death or successful spontaneous breathing trial. The primary endpoint of the study was feasibility, assessed as non-inferiority (5% tolerance) in the proportion of patients failing assisted ventilation. Secondary outcomes included safety, physiological parameters in the first week from randomization, 28-day mortality and ventilator-free days. Results: Two-hundred fifty-eight patients (31% women; median age 65 [54-75] years) were enrolled. In the Sigh group, 23% of patients failed to remain on assisted ventilation vs. 30% in the No Sigh group (absolute difference -7%, 95%CI -18% to 4%; p=0.015 for non-inferiority). Adverse events occurred in 12% vs. 13% in Sigh vs. No Sigh (p=0.852). Oxygenation was improved while tidal volume, respiratory rate and corrected minute ventilation were lower over the first 7 days from randomization in Sigh vs. No Sigh. There was no significant difference in terms of mortality (16% vs. 21%, p=0.342) and ventilator-free days (22 [7-26] vs. 22 [3-25] days, p=0.300) for Sigh vs. No Sigh. Interpretation: Among hypoxemic intubated ICU patients, application of sigh was feasible and without increased risk.

Published
2020

45. Are nephrometry scores accurate for the prediction of outcomes in patients with renal angiomyolipoma treated with robot-assisted partial nephrectomy? A multi-institutional analysis

Author

Uleri, A., primary, Diana, P., additional, Lughezzani, G., additional, Paciotti, M., additional, Casale, P., additional, Lazzeri, M., additional, Porpiglia, F., additional, Amparore, D., additional, Verri, P., additional, Mottrie, A., additional, Rosiello, G., additional, De Groote, R., additional, De Naeyer, G., additional, Porter, J., additional, and Buffi, N., additional

Published
2021
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46. Prostate biopsies by micro-ultrasound for clinically significant cancer detection: Results from a high-volume center

Author

Maffei, D., primary, Paciotti, M., additional, Avolio, P.P., additional, Frego, N., additional, Diana, P., additional, Fasulo, V., additional, Uleri, A., additional, Contieri, R., additional, Hurle, R., additional, Lazzeri, M., additional, Saita, A.R., additional, Casale, P., additional, Guazzoni, G.F., additional, Buffi, N.M., additional, and Lughezzani, G., additional

Published
2021
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47. Head-to-head comparison of high resolution micro-ultrasound and multiparametric magnetic resonance imaging for detecting extraprostatic extension in prostate cancer

Author

Paciotti, M., primary, Maffei, D., additional, Disconzi, L., additional, Regis, F., additional, Fasulo, V., additional, Persico, F., additional, Uleri, A., additional, Frego, N., additional, Colombo, P., additional, Mrakic-Sposta, F., additional, Balzarini, L., additional, Hurle, R., additional, Lazzeri, M., additional, Saita, A.R., additional, Casale, P., additional, Chiti, A., additional, Guazzoni, G.F., additional, Buffi, N.M., additional, and Lughezzani, G., additional

Published
2021
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48. Head-to-head comparison between high-resolution microultrasound imaging and multiparametric MRI in detecting and local staging of bladder cancer: the BUS-MISS protocol

Author

Beatrici, E., primary, Diana, P., additional, Uleri, A., additional, Saita, A., additional, Frego, N., additional, Contieri, R., additional, Buffi, N., additional, Balzarini, L., additional, D’Orazio, F., additional, Colombo, P., additional, Elefante, M.G., additional, Lazzeri, M., additional, Guazzoni, G., additional, Casale, P., additional, Hurle, R.F., additional, and Lughezzani, G., additional

Published
2021
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49. Micro-ultrasound guided prostate biopsies for clinically significant prostate cancer diagnosis in a cohort of biopsy-naive patients with MPMRI

Author

Chiarelli, G., primary, Maffei, D., additional, Avolio, P.P., additional, Paciotti, M., additional, Benevento, S., additional, Frego, N., additional, Diana, P., additional, Fasulo, V., additional, Colombo, P.G., additional, Lazzeri, M., additional, Hurle, R., additional, Saita, A.R., additional, Casale, P., additional, Guazzoni, G.F., additional, and Buffi, N.M., additional

Published
2021
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50. Active surveillance in low-grade non-muscle-invasive bladder cancers. Results after 8 years of bladder cancer Italian Active Surveillance (BIAS) project

Author

Contieri, R., primary, Frego, N., additional, Paciotti, M., additional, Diana, P., additional, Beatrici, E., additional, Avolio, P.P., additional, Uleri, A., additional, Fasulo, V., additional, Saita, A., additional, Casale, P., additional, Buffi, N.M., additional, Lughezzani, G., additional, Lazzeri, M., additional, Guazzoni, G., additional, and Hurle, R., additional

Published
2021
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