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1. Gender-stratified analysis of DLG5 R30Q in 4707 patients with Crohn disease and 4973 controls from 12 caucasian cohorts

Author

Browning, B.L., Annese, V., Braclay, M.L., Bingham, S.A., Brand, S., Buning, C., Castro, M., Cucchiara, S., Dallapiccola, B., Drummond, H., Ferguson, L.R., Ferraris, A., Fisher, S.A., Gearry, R.B., Glas, J., Henckaerts, L., Huebner, C., Knafelz, D., Lakatos, L., Lakatos, P.L., Latiano, A., Liu, X., Mathew, C., Muller-Myhsok, B., Newman, W.G., Nimmo, E.R., Noble, C.L., Palmieri, O., Parkes, M., Peterman, I., Rutgeerts, P., Satsangi, J., Shelling, A.N., Siminovitch, K.A., Torok, H.P., Tremelling, M., Vermeire, S., Valvano, M.R., and Witt, H.

Subjects
Crohn's disease -- Risk factors, Crohn's disease -- Genetic aspects, Sex factors in disease -- Research, Genetic research -- Reports, Health
Published
2008

5. ECCO Position statement on the use of biosimilars for inflammatory bowel disease-an update

Author

Danese, S. (Silvio), Fiorino, G. (Gionata), Raine, T. (Tim), Ferrante, M. (Marc), Kemp, K. (Karen), Kierkus, J. (J.), Lakatos, P.L. (Peter L.), Mantzaris, G.J. (Gerassimos ), van der Woude, J. (Janneke), Panes, J. (Julian), Peyrin-Biroulet, L. (Laurent), Danese, S. (Silvio), Fiorino, G. (Gionata), Raine, T. (Tim), Ferrante, M. (Marc), Kemp, K. (Karen), Kierkus, J. (J.), Lakatos, P.L. (Peter L.), Mantzaris, G.J. (Gerassimos ), van der Woude, J. (Janneke), Panes, J. (Julian), and Peyrin-Biroulet, L. (Laurent)

Published
2017
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6. 3rd European evidence-based consensus on the diagnosis and management of Crohn's disease 2016: Part 2: Surgical management and special situations

Author

Gionchetti, P. (Paolo), Dignass, A. (Axel), Danese, S. (Silvio), Dias, F.J.M. (Fernando José Magro), Rogler, G. (Gerhard), Lakatos, P.L. (Péter Laszlo), Adamina, M. (Michel), Ardizzone, S. (Sandro), Buskens, C.J. (Christianne), Sebastian, S. (Shaji), Laureti, S. (Silvio), Sampietro, G.M. (Gianluca M.), Vucelic, B. (B.), Woude, C.J. (Janneke) van der, Manuel Barreiro-de Acosta, (), Maaser, C. (Christian), Portela, F. (Francisco), Vavricka, S.R. (Stephan R.), Gomollón, F. (Fernando), Vito, A. (Annese), Marco, D. (Daperno), Alessandro, A. (Armuzzi), Gionata, F. (Fiorino), Fernando, R. (Rizzello), Silvio, D. (Danese), Sandro, A. (Ardizzone), Paolo, G. (Gionchetti), Gianluca, S. (Sampietro), Silvio, L. (Laureti), Kohn, A. (Anna), Simone, S. (Saibeni), Livia, B. (Biancone), Herbert, T. (Tilg), Garret, C. (Cullen), Colm O'Morain, (), Torsten, K. (Kucharzik), Axel, D. (Dignass), Jost, L. (Langhorst), Christian, M. (Maaser), Sturm, A. (Andreas), Lasitschka, F. (Felix), Florian, R. (Rieder), van Gert, A. (Assche), Bossuyt, P. (Peter), Sven, A. (Almer), Harbord, M. (Marcus), James, L. (Lindsay), Shaji, S. (Sebastian), Irving, P. (Peter), Miquel, S. (Sans), Fernando, G. (Gomollon), Manuel, B.D.A. (Barreiro De Acosta), Jorda, F.C. (Francesc Casellas), Federico, A.A. (Arguelles Arias), Laurent, P.-B. (Peyrin-Biroulet), Carbonnel, F. (Franck), Yehuda, C. (Chowers), Pascal, J. (Juillerat), Michel, A. (Adamina), Gerhard, R. (Rogler), Stephan, V. (Vavricka), Mantzaris Gerassimos, J. (J.), Koutroubakis, I. (Ioannis), Katsanos, K. (Konstantinos), Fernando, M. (Magro), Francisco, P. (Portela), Christianne, B. (Buskens), van der Woude, J. (Janneke), Boris, V. (Vucelic), Mijandrusic-Sincic, B. (Brankica), Peter, L. (Lakatos), Douda, T. (Thomas), Brynskov, J. (Jorn), Knudsen, T. (Torben), Manninen, P. (Pia), Berset, I.P. (Ingrid Prytz), Kierkus, J. (J.), Zagorowicz, E. (Edyta), Diculescu, M.M. (Mihai Mircea), Goldis, A.E. (Adrian Eugen), Potapov, A. (Alexander), Celik, A.F. (Aykut Ferhat), Aldis, P. (Pukitis), Gionchetti, P. (Paolo), Dignass, A. (Axel), Danese, S. (Silvio), Dias, F.J.M. (Fernando José Magro), Rogler, G. (Gerhard), Lakatos, P.L. (Péter Laszlo), Adamina, M. (Michel), Ardizzone, S. (Sandro), Buskens, C.J. (Christianne), Sebastian, S. (Shaji), Laureti, S. (Silvio), Sampietro, G.M. (Gianluca M.), Vucelic, B. (B.), Woude, C.J. (Janneke) van der, Manuel Barreiro-de Acosta, (), Maaser, C. (Christian), Portela, F. (Francisco), Vavricka, S.R. (Stephan R.), Gomollón, F. (Fernando), Vito, A. (Annese), Marco, D. (Daperno), Alessandro, A. (Armuzzi), Gionata, F. (Fiorino), Fernando, R. (Rizzello), Silvio, D. (Danese), Sandro, A. (Ardizzone), Paolo, G. (Gionchetti), Gianluca, S. (Sampietro), Silvio, L. (Laureti), Kohn, A. (Anna), Simone, S. (Saibeni), Livia, B. (Biancone), Herbert, T. (Tilg), Garret, C. (Cullen), Colm O'Morain, (), Torsten, K. (Kucharzik), Axel, D. (Dignass), Jost, L. (Langhorst), Christian, M. (Maaser), Sturm, A. (Andreas), Lasitschka, F. (Felix), Florian, R. (Rieder), van Gert, A. (Assche), Bossuyt, P. (Peter), Sven, A. (Almer), Harbord, M. (Marcus), James, L. (Lindsay), Shaji, S. (Sebastian), Irving, P. (Peter), Miquel, S. (Sans), Fernando, G. (Gomollon), Manuel, B.D.A. (Barreiro De Acosta), Jorda, F.C. (Francesc Casellas), Federico, A.A. (Arguelles Arias), Laurent, P.-B. (Peyrin-Biroulet), Carbonnel, F. (Franck), Yehuda, C. (Chowers), Pascal, J. (Juillerat), Michel, A. (Adamina), Gerhard, R. (Rogler), Stephan, V. (Vavricka), Mantzaris Gerassimos, J. (J.), Koutroubakis, I. (Ioannis), Katsanos, K. (Konstantinos), Fernando, M. (Magro), Francisco, P. (Portela), Christianne, B. (Buskens), van der Woude, J. (Janneke), Boris, V. (Vucelic), Mijandrusic-Sincic, B. (Brankica), Peter, L. (Lakatos), Douda, T. (Thomas), Brynskov, J. (Jorn), Knudsen, T. (Torben), Manninen, P. (Pia), Berset, I.P. (Ingrid Prytz), Kierkus, J. (J.), Zagorowicz, E. (Edyta), Diculescu, M.M. (Mihai Mircea), Goldis, A.E. (Adrian Eugen), Potapov, A. (Alexander), Celik, A.F. (Aykut Ferhat), and Aldis, P. (Pukitis)

Abstract

This paper is the second in a series of two publications relating to the European Crohn's and Colitis Organisation [ECCO] evidence-based consensus on the diagnosis and management of Crohn's disease [CD] and concerns the surgical management of CD as well as special situations including management of perianal CD and extraintestinal manifestations. Diagnostic approaches and medical management of CD of this ECCO Consensus are covered in the first paper [Gomollon et al. JCC 2016].

Published
2017
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7. The First European Evidence-Based Consensus on Extra-Intestinal Manifestations in Inflammatory Bowel Disease

Author

Harbord, M. (Marcus), Annese, V. (Vito), Vavricka, S.R. (Stephan), Allez, M. (Matthieu), Barreiro-de Acosta, M. (Manuel), Borberg, K. (Kirsten), Burisch, B. (Johan), Vos, M. (Martine) de, Vries, A.M. (Anne-Marie) de, Dick, A.D. (Andrew), Juillerat, P. (Pascal), Karlson, T. (Tom), Koutroubakis, L. (Loannis), Lakatos, P.L. (Peter), Orchard, T., Papay, P. (Pavol), Raine, T. (Tim), Reinshagen, M. (Max), Thaçi, D. (Diamant), Tilg, H. (Herbert), Carbonnel, F. (Franck), Harbord, M. (Marcus), Annese, V. (Vito), Vavricka, S.R. (Stephan), Allez, M. (Matthieu), Barreiro-de Acosta, M. (Manuel), Borberg, K. (Kirsten), Burisch, B. (Johan), Vos, M. (Martine) de, Vries, A.M. (Anne-Marie) de, Dick, A.D. (Andrew), Juillerat, P. (Pascal), Karlson, T. (Tom), Koutroubakis, L. (Loannis), Lakatos, P.L. (Peter), Orchard, T., Papay, P. (Pavol), Raine, T. (Tim), Reinshagen, M. (Max), Thaçi, D. (Diamant), Tilg, H. (Herbert), and Carbonnel, F. (Franck)

Published
2016
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8. Infliximab Reduces Endoscopic, but Not Clinical, Recurrence of Crohn’s Disease After Ileocolonic Resection

Author

Regueiro, Miguel, primary, Feagan, Brian G., additional, Zou, Bin, additional, Johanns, Jewel, additional, Blank, Marion A., additional, Chevrier, Marc, additional, Plevy, Scott, additional, Popp, John, additional, Cornillie, Freddy J., additional, Lukas, Milan, additional, Danese, Silvio, additional, Gionchetti, Paolo, additional, Hanauer, Stephen B., additional, Reinisch, Walter, additional, Sandborn, William J., additional, Sorrentino, Dario, additional, Rutgeerts, Paul, additional, Debinski, H., additional, Florin, T., additional, Hetzel, D., additional, Lawrance, I., additional, Radford-Smith, G., additional, Sloss, A., additional, Sorrentino, D., additional, Gassner, S., additional, Haas, T., additional, Reicht, G., additional, Reinisch, W., additional, Strasser, M., additional, Vogelsang, H., additional, Bossuyt, P., additional, DeWit, O., additional, D'Haens, G., additional, Franchimont, D., additional, Louis, E., additional, Vermeire, S., additional, Bernstein, C.N., additional, Bourdages, R., additional, Chiba, N., additional, Dhalla, S.S., additional, Feagan, B.G., additional, Fedorak, R.N., additional, Lachance, J.R., additional, Panaccione, R., additional, Ropeleski, M., additional, Singh Salh, B., additional, Lukas, M, additional, Colombel, J-F, additional, Allez, M., additional, Desreumaux, P., additional, Dupas, J.L., additional, Grimaud, J-C., additional, Hebuterne, X., additional, Laharie, D., additional, Lerebours, E., additional, Peyrin-Biroulet, L., additional, Reimund, J-M., additional, Viennot, S., additional, Zerbib, F., additional, Antoni, C., additional, Atreya, R., additional, Baumgart, D.C., additional, Berg, C., additional, Boecker, U., additional, Bramkamp, G., additional, Bünning, C., additional, Ehehalt, R., additional, Howaldt, S., additional, Kucharzik, T., additional, Lamprecht, H.G., additional, Mudter, J., additional, Preiss, J.C., additional, Schreiber, S., additional, Seidler, U., additional, Altorjay, I., additional, Banai, J., additional, Lakatos, P.L., additional, Varga, M., additional, Vincze, A., additional, Avni-Biron, I., additional, Fishman, S., additional, Fraser, G.M., additional, Goldin, E., additional, Rachmilewitz, D., additional, Annese, V., additional, Ardizzone, S., additional, Biancone, L., additional, Bossa, F., additional, Danese, S., additional, Fries, W., additional, Gionchetti, P., additional, Maconi, G., additional, Terrosu, G., additional, Usai, P., additional, D'Haens, G.R., additional, Gearry, R.B., additional, Hill, J., additional, Rowbotham, D.S., additional, Schultz, M., additional, Stubbs, R.S., additional, Wallace, D., additional, Walmsley, R.S., additional, Wyeth, J., additional, Malecka-Panas, E., additional, Paradowski, L., additional, Regula, J., additional, Beales, I.P., additional, Campbell, S., additional, Hawthorne, A.B., additional, Parkes, M., additional, Travis, S.P., additional, Achkar, J.P., additional, Behm, B.W., additional, Bickston, S.J., additional, Brown, K.J., additional, Chiorean, M.V., additional, DeVilliers, W.J.S., additional, Elliott, D.E., additional, Grunkmeier, D., additional, Hamilton, J.W., additional, Hanauer, S.B., additional, Hanson, J.S., additional, Hardi, R., additional, Helper, D.J., additional, Herfarth, H., additional, Higgins, P.D.R., additional, Holderman, W.H., additional, Kottoor, R., additional, Kreines, M.D., additional, Leman, B.I., additional, Li, X., additional, Loftus, E.V., additional, Noar, M., additional, Oikonomou, I., additional, Onken, J., additional, Peterson, K.A., additional, Phillips, R.P., additional, Randall, C.W., additional, Ricci, M., additional, Ritter, T., additional, Rubin, D.T., additional, Safdi, M., additional, Sandborn, W.J., additional, Sauberman, L., additional, Scherl, E., additional, Schwarz, R.P., additional, Sedghi, S., additional, Shafran, I., additional, Sninsky, C.A., additional, Stein, I., additional, Swoger, J., additional, Vecchio, J., additional, Weinberg, D.I., additional, Wruble, L.D., additional, Yajnik, V., additional, and Younes, Z., additional

Published
2016
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9. East-West gradient in the incidence of inflammatory bowel disease in Europe: the ECCO-EpiCom inception cohort

Author

Burisch, J., Pedersen, N., Cukovic-Cavka, S., Brinar, M., Kaimakliotis, I., Duricova, D., Shonova, O., Vind, I., Avnstrom, S., Thorsgaard, N., Andersen, V., Krabbe, S., Dahlerup, J.F., Salupere, R., Nielsen, K.R., Olsen, J., Manninen, P., Collin, P., Tsianos, E.V., Katsanos, K.H., Ladefoged, K., Lakatos, L., Bjornsson, E., Ragnarsson, G., Bailey, Y., Odes, S., Schwartz, D., Martinato, M., Lupinacci, G., Milla, M., De Padova, A., D'lnca, R., Beltrami, M., Kupcinskas, L., Kiudelis, G., Turcan, S., Tighineanu, O., Mihu, I., Magro, F., Barros, L.F., Goldis, A., Lazar, D., Belousova, E., Nikulina, I., Hernandez, V., Martinez-Ares, D., Almer, Sven, Zhulina, Y., Halfvarson, J., Arebi, N., Sebastian, S., Lakatos, P.L., Langholz, E., Munkholm, P., Burisch, J., Pedersen, N., Cukovic-Cavka, S., Brinar, M., Kaimakliotis, I., Duricova, D., Shonova, O., Vind, I., Avnstrom, S., Thorsgaard, N., Andersen, V., Krabbe, S., Dahlerup, J.F., Salupere, R., Nielsen, K.R., Olsen, J., Manninen, P., Collin, P., Tsianos, E.V., Katsanos, K.H., Ladefoged, K., Lakatos, L., Bjornsson, E., Ragnarsson, G., Bailey, Y., Odes, S., Schwartz, D., Martinato, M., Lupinacci, G., Milla, M., De Padova, A., D'lnca, R., Beltrami, M., Kupcinskas, L., Kiudelis, G., Turcan, S., Tighineanu, O., Mihu, I., Magro, F., Barros, L.F., Goldis, A., Lazar, D., Belousova, E., Nikulina, I., Hernandez, V., Martinez-Ares, D., Almer, Sven, Zhulina, Y., Halfvarson, J., Arebi, N., Sebastian, S., Lakatos, P.L., Langholz, E., and Munkholm, P.

Abstract

Objective The incidence of inflammatory bowel disease (IBD) is increasing in Eastern Europe. The reasons for these changes remain unknown. The aim of this study was to investigate whether an East–West gradient in the incidence of IBD in Europe exists. Design A prospective, uniformly diagnosed, population based inception cohort of IBD patients in 31 centres from 14 Western and eight Eastern European countries covering a total background population of approximately 10.1 million people was created. One-third of the centres had previous experience with inception cohorts. Patients were entered into a low cost, web based epidemiological database, making participation possible regardless of socioeconomic status and prior experience. Results 1515 patients aged 15 years or older were included, of whom 535 (35%) were diagnosed with Crohn's disease (CD), 813 (54%) with ulcerative colitis (UC) and 167 (11%) with IBD unclassified (IBDU). The overall incidence rate ratios in all Western European centres were 1.9 (95% CI 1.5 to 2.4) for CD and 2.1 (95% CI 1.8 to 2.6) for UC compared with Eastern European centres. The median crude annual incidence rates per 100 000 in 2010 for CD were 6.5 (range 0–10.7) in Western European centres and 3.1 (range 0.4–11.5) in Eastern European centres, for UC 10.8 (range 2.9–31.5) and 4.1 (range 2.4–10.3), respectively, and for IBDU 1.9 (range 0–39.4) and 0 (range 0–1.2), respectively. In Western Europe, 92% of CD, 78% of UC and 74% of IBDU patients had a colonoscopy performed as the diagnostic procedure compared with 90%, 100% and 96%, respectively, in Eastern Europe. 8% of CD and 1% of UC patients in both regions underwent surgery within the first 3 months of the onset of disease. 7% of CD patients and 3% of UC patients from Western Europe received biological treatment as rescue therapy. Of all European CD patients, 20% received only 5-aminosalicylates as induction therapy. Conclusions An East–West gradient in IBD incidence exists in Europe. Among

Published
2014
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10. The management of iron deficiency in inflammatory bowel disease

Author

Reinisch, W. (Walter), Chowers, Y. (Yehuda), Danese, S. (Silvio), Dignass, A. (Axel), Gomollõn, F., Haagen Nielsen, O., Lakatos, P.L. (Peter), Lees, C.W. (Charlie), Lindgren, S., Lukas, M.A. (Mary Ann), Mantzaris, G.J. (Gerassimos ), Michetti, P. (Pierre), Moum, B., Peyrin-Biroulet, L. (Laurent), Toruner, M., Woude, C.J. (Janneke) van der, Weiss, G. (Gunter), Stoevelaar, H. (Herman), Reinisch, W. (Walter), Chowers, Y. (Yehuda), Danese, S. (Silvio), Dignass, A. (Axel), Gomollõn, F., Haagen Nielsen, O., Lakatos, P.L. (Peter), Lees, C.W. (Charlie), Lindgren, S., Lukas, M.A. (Mary Ann), Mantzaris, G.J. (Gerassimos ), Michetti, P. (Pierre), Moum, B., Peyrin-Biroulet, L. (Laurent), Toruner, M., Woude, C.J. (Janneke) van der, Weiss, G. (Gunter), and Stoevelaar, H. (Herman)

Abstract

__Background__ Iron deficiency is a common and undertreated problem in inflammatory bowel disease (IBD). __Aim__ To develop an online tool to support treatment choice at the patient-specific level. __Methods__ Using the RAND/UCLA Appropriateness Method (RUAM), a European expert panel assessed the appropriateness of treatment regimens for a variety of clinical scenarios in patients with non-anaemic iron deficiency (NAID) and iron deficiency anaemia (IDA). Treatment options included adjustment of IBD medication only, oral iron supplementation, high-/low-dose intravenous (IV) regimens, IV iron plus erythropoietin-stimulating agent (ESA), and blood transfusion. The panel process consisted of two individual rating rounds and three plenary discussion meetings. __Results__ The panel reached agreement on 71% of treatment indications. 'No treatment' was never considered appropriate, and repeat treatment after previous failure was generally discouraged. For 98% of scenarios, at least one treatment was appropriate. Adjustment of IBD medication was deemed appropriate in all patients with active disease. Use of oral iron was mainly considered an option in NAID and mildly anaemic patients without disease activity. IV regimens were often judged appropriate, with high-dose IV iron being the preferred option in 77% of IDA scenarios. Blood transfusion and IV+ESA were indicated in exceptional cases only. __Conclusions__ The RUAM revealed high agreement amongst experts on the management of iron deficiency in patients with IBD. High-dose IV iron was more often considered appropriate than other options. To facilitate dissemination of the recommendations, panel outcomes were embedded in an online tool, accessible via http://ferroscope.com/.

Published
2013
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11. P285 COMPARING CONVENTIONAL AND GASCA TESTS FOR THE DIAGNOSIS AND DETERMINATION OF CLINICAL PHENOTYPE IN CROHN'S DISEASE

Author

Lakatos, P.L., primary, Altorjay, I., additional, Dotan, N., additional, Tumpek, J., additional, Sipka, S., additional, Lakos, G., additional, Palatka, K., additional, Lakatos, L., additional, Kovacs, A., additional, Molnar, T., additional, Tulassay, Z., additional, Miheller, P., additional, Norman, G.L., additional, Szamosi, T., additional, and Maria, P., additional

Published
2008
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12. P209 NFKBIA 3'UTR AND NFKB1 -94INS/DELATTG VARIANTS IN HUNGARIAN IBD PATIENTS: THE 3'UTR VARIANT IS ASSOCIATED WITH EXTENSIVE COLITIS

Author

Szamosi, T., primary, Szilvasi, A., additional, Lakatos, L., additional, Kovacs, A., additional, Molnar, T., additional, Altorjay, I., additional, Papp, M., additional, Szabo, O., additional, Satori, A., additional, Tulassay, Z., additional, Miheller, P., additional, Papp, J., additional, Tordai, A., additional, Andrikovics, H., additional, and Lakatos, P.L., additional

Published
2008
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16. P253 NEW SEROLOGICAL MARKERS FOR INFLAMMATORY BOWEL DISEASE ARE ASSOCIATED WITH EARLIER AGE AT ONSET, COMPLICATED DISEASE BEHAVIOR, RISK FOR SURGERY, AND NOD2/CARD15 GENOTYPE IN A HUNGARIAN IBD COHORT

Author

Papp, M., primary, Altorjay, I., additional, Dotan, N., additional, Palatka, K., additional, Foldi, I., additional, Tumpek, J., additional, Sipka, S., additional, Udvardy, M., additional, Lakatos, L., additional, Kovacs, A., additional, Molnar, T., additional, Tulassay, Z., additional, Miheller, P., additional, Szamosi, T., additional, and Lakatos, P.L., additional

Published
2008
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18. P120 THE ATP-BINDING CASSETTE TRANSPORTER ABCG2 (BCRP) AND ABCB1 (MDR1) VARIANTS ARE NOT ASSOCIATED WITH DISEASE SUSCEPTIBILITY, DISEASE PHENOTYPE, RESPONSE TO MEDICAL THERAPY OR NEED FOR SURGERY IN HUNGARIAN PATIENTS WITH INFLAMMATORY BOWEL DISEASES

Author

Lakatos, P.L., primary, Fischer, S., additional, Lakatos, L., additional, Kovacs, A., additional, Molnar, T., additional, Altorjay, I., additional, Papp, M., additional, Szilvasi, A., additional, Tulassay, Z., additional, Osztovits, J., additional, Papp, J., additional, and Demeter, P., additional

Published
2007
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19. ECCO Guidelines on Therapeutics in Ulcerative Colitis: Medical Treatment

Author

Tim Raine, Stefanos Bonovas, Johan Burisch, Torsten Kucharzik, Michel Adamina, Vito Annese, Oliver Bachmann, Dominik Bettenworth, Maria Chaparro, Wladyslawa Czuber-Dochan, Piotr Eder, Pierre Ellul, Catarina Fidalgo, Gionata Fiorino, Paolo Gionchetti, Javier P Gisbert, Hannah Gordon, Charlotte Hedin, Stefan Holubar, Marietta Iacucci, Konstantinos Karmiris, Konstantinos Katsanos, Uri Kopylov, Peter L Lakatos, Theodore Lytras, Ivan Lyutakov, Nurulamin Noor, Gianluca Pellino, Daniele Piovani, Edoardo Savarino, Francesco Selvaggi, Bram Verstockt, Antonino Spinelli, Yves Panis, Glen Doherty, Raine T., Bonovas S., Burisch J., Kucharzik T., Adamina M., Annese V., Bachmann O., Bettenworth D., Chaparro M., Czuber-Dochan W., Eder P., Ellul P., Fidalgo C., Fiorino G., Gionchetti P., Gisbert J.P., Gordon H., Hedin C., Holubar S., Iacucci M., Karmiris K., Katsanos K., Kopylov U., Lakatos P.L., Lytras T., Lyutakov I., Noor N., Pellino G., Piovani D., Savarino E., Selvaggi F., Verstockt B., Spinelli A., Panis Y., Doherty G., Raine, Tim, Bonovas, Stefano, Burisch, Johan, Kucharzik, Torsten, Adamina, Michel, Annese, Vito, Bachmann, Oliver, Bettenworth, Dominik, Chaparro, Maria, Czuber-Dochan, Wladyslawa, Eder, Piotr, Ellul, Pierre, Fidalgo, Catarina, Fiorino, Gionata, Gionchetti, Paolo, Gisbert, Javier P, Gordon, Hannah, Hedin, Charlotte, Holubar, Stefan, Iacucci, Marietta, Karmiris, Konstantino, Katsanos, Konstantino, Kopylov, Uri, Lakatos, Peter L, Lytras, Theodore, Lyutakov, Ivan, Noor, Nurulamin, Pellino, Gianluca, Piovani, Daniele, Savarino, Edoardo, Selvaggi, Francesco, Verstockt, Bram, Spinelli, Antonino, Panis, Yve, Doherty, Glen, Raine, T., Bonovas, S., Burisch, J., Kucharzik, T., Adamina, M., Annese, V., Bachmann, O., Bettenworth, D., Chaparro, M., Czuber-Dochan, W., Eder, P., Ellul, P., Fidalgo, C., Fiorino, G., Gionchetti, P., Gisbert, J. P., Gordon, H., Hedin, C., Holubar, S., Iacucci, M., Karmiris, K., Katsanos, K., Kopylov, U., Lakatos, P. L., Lytras, T., Lyutakov, I., Noor, N., Pellino, G., Piovani, D., Savarino, E., Selvaggi, F., Verstockt, B., Spinelli, A., Panis, Y., and Doherty, G.

Subjects
"guidelines", Gastroenterology, "ulcerative colitis", Humans, "ulcerative colitis", "guidelines", "medical management", Colitis, Ulcerative, General Medicine, Severity of Illness Index, "medical management", Human
Abstract

hese recommendations summarise the current evidence on the medical management of adult patients with UC. Gaps were iden-tified during the analysis of the data, which should be addressed by further research. Where evidence is lacking or is very weak and evidence-based recommendations cannot be given, ECCO provides alternative tools, such as Topical Reviews28,95,153–158 or Position Papers.159–161 It is important that clinicians use these guidelines within the framework of local regulations, and seek to understand and address the individual needs and expectations of every patient. We recognise that constraints on health care resources are an im-portant factor in determining whether recommendations can be implemented for patients in many countries. The recommendations outlined here should be used to inform treatment decisions and form part of an overall multidisciplinary treatment plan for patients with UC, which may also encompass psychological, nutritional, and other non-pharmacological interventions.

Published
2022

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