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Your search keyword '"Kinnari, T."' showing total 13 results
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13 results on '"Kinnari, T."'

1. Finnish version of the eating assessment tool (F-EAT-10):a valid and reliable patient-reported outcome measure for dysphagia evaluation

Author

Järvenpää, P. (Pia), Kuuskoski, J. (Jonna), Pietarinen, P. (Petra), Markkanen-Leppänen, M. (Mari), Freiberg, H. (Hanna), Ruuskanen, M. (Miia), Rekola, J. (Jami), Ilmarinen, T. (Taru), Kinnari, T. J. (Teemu J.), Autio, T. J. (Timo J.), Penttilä, E. (Elina), Muttilainen, M. S. (Marika S.), Laaksonen, A. (Annika), Oksanen, L. (Lotta), Geneid, A. (Ahmed), Aaltonen, L.-M. (Leena-Maija), Järvenpää, P. (Pia), Kuuskoski, J. (Jonna), Pietarinen, P. (Petra), Markkanen-Leppänen, M. (Mari), Freiberg, H. (Hanna), Ruuskanen, M. (Miia), Rekola, J. (Jami), Ilmarinen, T. (Taru), Kinnari, T. J. (Teemu J.), Autio, T. J. (Timo J.), Penttilä, E. (Elina), Muttilainen, M. S. (Marika S.), Laaksonen, A. (Annika), Oksanen, L. (Lotta), Geneid, A. (Ahmed), and Aaltonen, L.-M. (Leena-Maija)

Abstract

Our aim was to validate a Finnish version of the Eating Assessment Tool (F-EAT-10) for clinical use and to test its reliability and validity in a multicenter nationwide study. Normative data were acquired from 180 non-dysphagic participants (median age 57.0 years, 62.2% female). Dysphagia patients (n = 117, median age 69.7 years, 53.0% female) referred to fiberoptic endoscopic evaluation of swallowing (FEES) completed F-EAT-10 before the examination and after 2 weeks. Patients underwent the 100-ml water swallow test (WST) and FEES was evaluated using the following three scales: the Yale Pharyngeal Residue Severity Rating Scale, Penetration-Aspiration Scale, and the Dysphagia Outcome Severity Scale. An operative cohort of 19 patients (median age 75.8 years, 57.9% female) underwent an endoscopic operation on Zenker’s diverticulum, tight cricopharyngeal muscle diagnosed in videofluorography, or both. Patients completed the F-EAT-10 preoperatively and 3 months postoperatively. The cut-off score for controls was < 3 (sensitivity 94.0%, specificity 96.1%) suggesting that ≥ 3 is abnormal. Re-questionnaires for test–retest reliability analysis were available from 92 FEES patients and 123 controls. The intraclass correlation coefficient was excellent for the total F-EAT-10 score (0.93, 95% confidence interval 0.91–0.95). Pearson correlation coefficients were strong (p < 0.001) for each of the questions and the total score. Internal consistency as assessed by Cronbach’s alpha was excellent (0.95). Some correlations between findings in FEES and 100-ml WST with F-EAT-10 were observed. The change in subjective symptoms of operative patients paralleled the change in F-EAT-10. F-EAT-10 is a reliable, valid, and symptom-specific patient-reported outcome measure for assessing dysphagia among Finnish speakers.

Published
2022

4. Union of the European Phoniatricians position statement on the exit strategy of phoniatric and laryngological services: staying safe and getting back to normal after the peak of coronavirus disease 2019 (issued on 25th May 2020)

Author

Geneid, A., Nawka, T., Schindler, A., Oguz, H., Chrobok, V, Calcinoni, O., Am Zehnhoff-Dinnesen, A., Neumann, K., Farahat, M., Abou-Elsaad, T., Moerman, M., Chavez, E., Fishman, J., Yazaki, R., Arnold, B., Frajkova, Z., Graf, S., Pflug, C., Drsata, J., Desuter, G., Samuelsson, Christina, Tedla, M., Costello, D., Sjogren, E., Hess, M., Kinnari, T., Rubin, J., Geneid, A., Nawka, T., Schindler, A., Oguz, H., Chrobok, V, Calcinoni, O., Am Zehnhoff-Dinnesen, A., Neumann, K., Farahat, M., Abou-Elsaad, T., Moerman, M., Chavez, E., Fishman, J., Yazaki, R., Arnold, B., Frajkova, Z., Graf, S., Pflug, C., Drsata, J., Desuter, G., Samuelsson, Christina, Tedla, M., Costello, D., Sjogren, E., Hess, M., Kinnari, T., and Rubin, J.

Abstract

Background The following position statement from the Union of the European Phoniatricians, updated on 25th May 2020 (superseding the previous statement issued on 21st April 2020), contains a series of recommendations for phoniatricians and ENT surgeons who provide and/or run voice, swallowing, speech and language, or paediatric audiology services. Objectives This material specifically aims to inform clinical practices in countries where clinics and operating theatres are reopening for elective work. It endeavours to present a current European view in relation to common procedures, many of which fall under the aegis of aerosol generating procedures. Conclusion As evidence continues to build, some of the recommended practices will undoubtedly evolve, but it is hoped that the updated position statement will offer clinicians precepts on safe clinical practice.

Published
2020
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9. Tryptophan 272: an essential determinant of crystalline cellulose degradation by Trichoderma reesei cellobiohydrolase Cel6A (FEBS 20361) (vol 429, pg 341, 1998)

Author

Koivula, A, Kinnari, T, Harjunpaa, V, Ruohonen, L, Teleman, A, Drakenberg, T, Rouvinen, J, Jones, TA, Teeri, TT, Koivula, A, Kinnari, T, Harjunpaa, V, Ruohonen, L, Teleman, A, Drakenberg, T, Rouvinen, J, Jones, TA, and Teeri, TT

Abstract

Addresses: Koivula A, VTT, Biotechnol & Food Res, POB 1500, FIN-02044 Espoo, Finland. VTT, Biotechnol & Food Res, FIN-02044 Espoo, Finland. VTT, Chem Technol, FIN-02044 Espoo, Finland. BMC, Dept Biol Mol, S-75124 Uppsala, Sweden.

Published
1999

10. Tryptophan 272: an essential determinant of crystalline cellulose degradation by Trichoderma reesei cellobiohydrolase Cel6A

Author

Koivula, A, Kinnari, T, Harjunpaa, V, Ruohonen, L, Teleman, A, Drakenberg, T, Rouvinen, J, Jones, TA, Teeri, TT, Koivula, A, Kinnari, T, Harjunpaa, V, Ruohonen, L, Teleman, A, Drakenberg, T, Rouvinen, J, Jones, TA, and Teeri, TT

Abstract

Trichoderma reesei cellobiohydrolase Cel6A (formerly CBHII) has a tunnel shaped active site with four internal subsites for the glucose units. We have predicted an additional ring stacking interaction for a sixth glucose moiety with a tryptophan residue (, Addresses: Teeri TT, Kungliga Tekniska Hogskolan, Dept Biochem & Biotechnol, S-10044 Stockholm, Sweden. VTT Biotechnol & Food Res, FIN-02044 Espoo, Finland. VTT Chem Technol, FIN-02044 Espoo, Finland. BMC, Dept Biol Mol, S-75124 Uppsala, Sweden.

Published
1998

12. Efficient management of benign laryngeal symptoms in an endoscopy outpatient clinic.

Author

Järvenpää P, Kinnari T, Pietarinen P, and Ilmarinen T

Abstract

Objectives: A globus and thick mucus in the throat are common reasons for referral to an ear, nose, and throat (ENT) specialist. ENT outpatient appointments focus on nasolaryngoscopy examinations, patient education, and reassurance. An endoscopic outpatient clinic (EOC) was established to efficiently manage patients with benign laryngeal symptoms., Methods: Patients referred between February 2022 and June 2023 due to a globus and/or thick mucus in the throat were immediately contacted via post. The contact letter included patient education about the potential underlying reasons for their symptoms and self-care instructions. A 15-min outpatient visit was scheduled for an ENT examination and nasolaryngoscopy. Patients completed a questionnaire about their current symptoms and whether they had followed the self-care instructions just before visiting the EOC and 1-month following their appointment., Results: In total, 203 patients examined in the EOC were included in the study. Before the EOC visit, most patients (89.2%) considered the information letter useful, it relieved concerns in 44.2% of patients, and 73.2% patients had already followed the self-care instructions. After the 1-month follow-up period, symptoms diminished significantly ( p  < .001)., Conclusions: Instructions for self-care and encouragement relieved concerns among patients with benign laryngeal symptoms. Moreover, symptoms improved significantly after a 1-month follow-up period., Level of Evidence: 4., Competing Interests: The authors declare no conflicts of interest., (© 2024 The Authors. Laryngoscope Investigative Otolaryngology published by Wiley Periodicals LLC on behalf of The Triological Society.)

Published
2024
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13. Estimating head-related transfer functions of human subjects from pressure-velocity measurements.

Author

Hiipakka M, Kinnari T, and Pulkki V

Subjects
Acoustic Stimulation, Acoustics instrumentation, Adult, Cues, Energy Transfer physiology, Evoked Potentials, Auditory physiology, Head, Hearing physiology, Humans, Male, Middle Aged, Models, Anatomic, Phonons, Pressure, Sound Localization physiology, Young Adult, Sound, Tympanic Membrane physiology
Abstract

Direct measurements of individual head-related transfer functions (HRTFs) with a probe microphone at the eardrum are unpleasant, risky, and unreliable and therefore have not been widely used. Instead, the HRTFs are commonly measured from the blocked ear canal entrance, which excludes the effects of the individual ear canals and eardrums. This paper presents a method that allows obtaining individually correct magnitude frequency responses of HRTFs at the eardrum from pressure-velocity (PU) measurements at the ear canal entrance with a miniature PU sensor. The HRTFs of 25 test subjects with nine directions of sound incidence were estimated using real anechoic measurements and an energy-based estimation method. To validate the approach, measurements were also conducted with probe microphones near the eardrums as well as at blocked ear canal entrances. Comparisons between the different methods show that the method presented is a valid and reliable technique for obtaining magnitude frequency responses of HRTFs. The HRTF filters designed using the PU measurements are also shown to yield more correct frequency responses at the eardrum than the filters designed using measurements from the blocked ear canal entrance.

Published
2012
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