1. Plasmablastic lymphoma: oral presentation in patient suffering from osteradionecrosis of the jaw
- Author
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Kichenbrand, C., Egloff, C., Guillet, J., Delaître, B., Bastien, C., Leroux, A., Dolivet, G., Phulpin, B., Ingénierie Moléculaire et Physiopathologie Articulaire (IMoPA), Université de Lorraine (UL)-Centre National de la Recherche Scientifique (CNRS), Laboratoire Chrono-environnement - CNRS - UBFC (UMR 6249) (LCE), Université de Franche-Comté (UFC), Université Bourgogne Franche-Comté [COMUE] (UBFC)-Université Bourgogne Franche-Comté [COMUE] (UBFC)-Centre National de la Recherche Scientifique (CNRS), Institut de Cancérologie de Lorraine - Alexis Vautrin [Nancy] (UNICANCER/ICL), and UNICANCER
- Subjects
stomatognathic diseases ,stomatognathic system ,Osteoradionecrosis ,Radiotherapy ,hemic and lymphatic diseases ,Head and neck oncology ,[SDV]Life Sciences [q-bio] ,Case Report ,Plasmablastic lymphoma ,ComputingMilieux_MISCELLANEOUS - Abstract
Highlights • Unusual buccal plasmablastic lymphoma. • In a immunocometent patient. • Suffering from osteoradionecrosis after head and neck radiotherapy., Introduction We describe here an unusual presentation of a plasmablastic lymphoma in a patient suffering from an osteoradionecrosis of the jaw. Presentation of case We report the case of a 64-year-old patient who was followed up on oncology because of an oropharyngeal cancer treated by a combined procedure of both surgery and radio-chemotherapy procedure. This patient developed an osteoradionecrosis of the jaw. In the vicinity of this necrotic area appeared an ulceration which could evoke a new necrotic area. Given the persistence of this ulceration, a biopsy was performed which highlighted a plasmablastic lymphoma oral localization. Discussion The plasmablastic lymphoma, belonging to the diffuse large B-cell lymphoma family, is a very aggressive and unusual form of cancer with poor prognosis. If it is found mainly in patients with positive HIV, in whom it was first described, it is also found in immunosuppressed patients such as transplanted patients or patients suffering from leukaemia. Conclusion Plasmablastic lymphoma is a rare and an aggressive pathology in immunocompetent patients.
- Published
- 2016