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Archaeologists have traditionally framed the impacts of natural disasters in terms of societal collapse versus cultural resilience. The 7.3ka cal BP Kikai-Akahoya (K-Ah) ‘super-eruption’ in south-western Japan was among the largest volcanic events of the Holocene. Here, the authors deploy a multi-proxy approach to examine how K-Ah devastated Tanegashima Island. While local Jōmon populations were annihilated, surrounding communities survived and eventually returned, adjusting their subsistence base to survive in the damaged environment. The article concludes that neither ‘collapse’ nor ‘resilience’ fully capture the complex dynamics of this process and that more research is needed to understand how disasters shape cultural trajectories.

Background The benefits of early continuous neuromuscular blockade in patients with acute respiratory distress syndrome (ARDS) who are receiving mechanical ventilation remain unclear. Meth...

Importance Data on the efficacy of hydroxychloroquine for the treatment of coronavirus disease 2019 (COVID-19) are needed. Objective To determine whether hydroxychloroquine is an efficacious treatment for adults hospitalized with COVID-19. Design, Setting, and Participants This was a multicenter, blinded, placebo-controlled randomized trial conducted at 34 hospitals in the US. Adults hospitalized with respiratory symptoms from severe acute respiratory syndrome coronavirus 2 infection were enrolled between April 2 and June 19, 2020, with the last outcome assessment on July 17, 2020. The planned sample size was 510 patients, with interim analyses planned after every 102 patients were enrolled. The trial was stopped at the fourth interim analysis for futility with a sample size of 479 patients. Interventions Patients were randomly assigned to hydroxychloroquine (400 mg twice daily for 2 doses, then 200 mg twice daily for 8 doses) (n = 242) or placebo (n = 237). Main Outcomes and Measures The primary outcome was clinical status 14 days after randomization as assessed with a 7-category ordinal scale ranging from 1 (death) to 7 (discharged from the hospital and able to perform normal activities). The primary outcome was analyzed with a multivariable proportional odds model, with an adjusted odds ratio (aOR) greater than 1.0 indicating more favorable outcomes with hydroxychloroquine than placebo. The trial included 12 secondary outcomes, including 28-day mortality. Results Among 479 patients who were randomized (median age, 57 years; 44.3% female; 37.2% Hispanic/Latinx; 23.4% Black; 20.1% in the intensive care unit; 46.8% receiving supplemental oxygen without positive pressure; 11.5% receiving noninvasive ventilation or nasal high-flow oxygen; and 6.7% receiving invasive mechanical ventilation or extracorporeal membrane oxygenation), 433 (90.4%) completed the primary outcome assessment at 14 days and the remainder had clinical status imputed. The median duration of symptoms prior to randomization was 5 days (interquartile range [IQR], 3 to 7 days). Clinical status on the ordinal outcome scale at 14 days did not significantly differ between the hydroxychloroquine and placebo groups (median [IQR] score, 6 [4-7] vs 6 [4-7]; aOR, 1.02 [95% CI, 0.73 to 1.42]). None of the 12 secondary outcomes were significantly different between groups. At 28 days after randomization, 25 of 241 patients (10.4%) in the hydroxychloroquine group and 25 of 236 (10.6%) in the placebo group had died (absolute difference, −0.2% [95% CI, −5.7% to 5.3%]; aOR, 1.07 [95% CI, 0.54 to 2.09]). Conclusions and Relevance Among adults hospitalized with respiratory illness from COVID-19, treatment with hydroxychloroquine, compared with placebo, did not significantly improve clinical status at day 14. These findings do not support the use of hydroxychloroquine for treatment of COVID-19 among hospitalized adults. Trial Registration ClinicalTrials.gov:NCT04332991

The invention of pottery was a fundamental technological advancement with far-reaching economic and cultural consequences. Pottery containers first emerged in East Asia during the Late Pleistocene in a wide range of environmental settings, but became particularly prominent and much more widely dispersed after climatic warming at the start of the Holocene. Some archaeologists argue that this increasing usage was driven by environmental factors, as warmer climates would have generated a wider range of terrestrial plant and animal resources that required processing in pottery. However, this hypothesis has never been directly tested. Here, in one of the largest studies of its kind, we conducted organic residue analysis of >800 pottery vessels selected from 46 Late Pleistocene and Early Holocene sites located across the Japanese archipelago to identify their contents. Our results demonstrate that pottery had a strong association with the processing of aquatic resources, irrespective of the ecological setting. Contrary to expectations, this association remained stable even after the onset of Holocene warming, including in more southerly areas, where expanding forests provided new opportunities for hunting and gathering. Nevertheless, the results indicate that a broader array of aquatic resources was processed in pottery after the start of the Holocene. We suggest this marks a significant change in the role of pottery of hunter-gatherers, corresponding to an increased volume of production, greater variation in forms and sizes, the rise of intensified fishing, the onset of shellfish exploitation, and reduced residential mobility.

The goal of this contribution is to stimulate a wider reflection on the role of food consumption practices throughout prehistory. We focussed on the Jōmon communities of Hokkaidō Island in Northern Japan since these mobile foragers underwent a process of economic diversification and intensification, eventually leading to higher levels of sedentism across the Pleistocene-Holocene transition. Moreover, dynamic social settings and expansion of the subsistence base at the start of the Holocene would have provided rich opportunities for novelfood combinations, and potentially, the rise of diverse regional cuisines. We investigated tool kits and resource landscapes, and sampled pottery from a range of sites, phases and regions. We then applied organic residueanalysis to confirm the actual spatiotemporal patterning in cuisine. Although we predicted that ruminants and nuts would have played a major role in local cuisine, especially in inland areas, our results indicate that aquaticresources were central to pottery-based cuisines across the island, and that other food groups had probably been processed in other ways. While organic residue analysis enabled us to reconstruct some major patterns in Jōmoncuisine, we conclude that archaeologists will need to look “beyond the cooking pot” to fully appreciate the full diversity of local foodways.

The Neolithic is a key topic in the study of Old World prehistory but how the Neolithic is defined varies between regions. In East Asia the invention of pottery is often seen as marking the start of the Neolithic. In contrast to this ‘eastern’ perspective, in western parts of Eurasia it is the presence of agriculture that usually defines the onset of a Neolithic way of life. This paper adopts a comparative perspective, examining the origins and development of pottery, agriculture and sedentary life in East Asia and Southwest Asia. We suggest that a comparative perspective indicates that some of the most enduring themes of Neolithic studies need to be reconsidered, namely: (1) the idea of a Neolithic package consisting of a number of associated traits (including, among other things, agriculture, sedentary sites, and pottery) that developed and spread together, (2) the notion of the Neolithic as a revolutionary event marking a sharp break from the preceding Palaeolithic period, and (3) the enduring impact of the Neolithic on later periods.

Copyright © 2016 Antiquity Publications Ltd. Where did pottery first appear in the Old World? Statistical modelling of radiocarbon dates suggests that ceramic vessel technology had independent origins in two different hunter-gatherer societies. Regression models were used to estimate average rates of spread and geographic dispersal of the new technology. The models confirm independent origins in East Asia (c. 16000 cal BP) and North Africa (c. 12000 cal BP). The North African tradition may have later influenced the emergence of Near Eastern pottery, which then flowed west into Mediterranean Europe as part of a Western Neolithic, closely associated with the uptake of farming.

The Neolithic in north-east Asia is defined by the presence of ceramic containers, rather than agriculture, among hunter-gatherer communities. The role of pottery in such groups has, however, hitherto been unclear. This article presents the results of organic residue analysis of Neolithic pottery from Sakhalin Island in the Russian Far East. Results indicate that early pottery on Sakhalin was used for the processing of aquatic species, and that its adoption formed part of a wider Neolithic transition involving the reorientation of local lifeways towards the exploitation of marine resources.

The invention of ceramic objects made from fire-hardened clay represents an important and early step in the development of pyrotechnology. This paper examines pottery invention and innovation by hunter-gatherers in East Asia and by farmers in the Near East to examine how prehistoric communities in different socio-economic systems came to rely heavily on fired-clay containers. Drawing on advances in archaeological science, it examines from a comparative perspective early pottery's broader entanglements related to technology and use and argues that early pottery production by farmers in the Near East can be viewed as a process of innovation in a longer tradition of container technology, while the first hunter-gatherer pottery production in East Asia provides a better case for independent invention.

Compared to the Pre-Pottery Neolithic B (PPNB), evidence for potentially symbolic imagery is rare in the Late Neolithic of the Southern Levant, consisting primarily of figurines and decorated pottery. While the symbolic roles of fi gurines have occasionally been discussed, studies of decorated pottery have usually focused on developing chronologies or defirning the boundaries of archaeological cultures. In an attempt to better understand pottery symbolism this paper suggests that over the course of the Late Neolithic pottery decoration became more varied but also became simpler. These developments may refl ect an increase of symbolic ambiguity. The decline in fi gurine use over the course of the Late Neolithic similarly suggests a focus on ambiguous symbols during the later part of the period. A tentative suggestion is that this shift may be related to a change in community organization. Some early Late Neolithic sites are relatively large and each one may have comprised a single, spatially contiguous community. In the later part of the period, at least in some areas, community groups may have been dispersed across several small sites. A symbolic system emphasizing ambiguity may have facilitated the occasional interactions that were a part of such dispersed communities., Dans la région du Levant Sud, les témoins potentiels d’une imagerie symbolique sont peu nombreux au Néolithique récent, contrairement au Néolithique précéramique B, et se composent principalement de figurines et de poterie décorée. Si le rôle symbolique des figurines a parfois été abordé par les chercheurs, les études portant sur la poterie décorée ont surtout servi à la mise en place de chronologies et à la définition de cultures archéologiques. Afin de mieux comprendre le rôle symbolique joué par la poterie, le présent article suggère que le décor des céramiques s’est non seulement diversifié, mais également simplifié tout au long du Néolithique récent. Ces développements pourraient être le reflet d’une ambiguïté symbolique croissante. Une diminution de l’utilisation des figurines au cours du Néolithique récent pourrait aussi refléter une nouvelle préférence pour les symboles ambigus à la fi n de cette période. Il est possible qu’une telle transformation soit reliée à un changement dans l’organisation sociale des communautés qui est perceptible à la même époque. Au début du Néolithique récent quelques sites très étendus suggèrent l’occupation d’un espace contigu par des communautés entières, tandis que la fi n du Néolithique récent voit une dispersion des communautés entre plusieurs petits sites, au moins dans certaines régions. Un système symbolique mettant l’accent sur l’ambiguïté a pu faciliter les interactions sociales épisodiques que nécessitait une telle dispersion des communautés., Gibbs Kevin. Late Neolithic Pottery and Ambiguous Symbols in the Southern Levant. In: Paléorient, 2013, vol. 39, n°2. pp. 69-84.

This article examines Siberia’s increasingly important role in the study of the emergence of pottery across northern Eurasia. The world’s earliest pottery comes from Late Pleistocene hunter-gatherer sites in East Asia. This material is typically seen as disconnected from later pottery traditions in Europe, which are generally associated with sedentary farmers. However, new evidence suggests that Asian and European pottery traditions may be linked to a Hyperborean stream of hunter-gatherer pottery dispersals that spanned eastern and western Asia, and introduced pottery into the prehistoric societies of northern Europe. As a potential bridge between the eastern and western early pottery traditions, Siberia’s prehistory is therefore set to play an increasingly central role in one of world archaeology’s most important debates.

The earliest pots in the world are from East Asia and date to the Late Pleistocene. However, ceramic vessels were only produced in large numbers during the warmer and more stable climatic conditions of the Holocene. It has long been assumed that the expansion of pottery was linked with increased sedentism and exploitation of new resources that became available with the ameliorated climate, but this hypothesis has never been tested. Through chemical analysis of their contents, we herein investigate the use of pottery across an exceptionally long 9,000-y sequence from the Jomon site of Torihama in western Japan, intermittently occupied from the Late Pleistocene to the mid-Holocene. Molecular and isotopic analyses of lipids from 143 vessels provides clear evidence that pottery across this sequence was predominantly used for cooking marine and freshwater resources, with evidence for diversification in the range of aquatic products processed during the Holocene. Conversely, there is little indication that ruminant animals or plants were processed in pottery, although it is evident from the faunal and macrobotanical remains that these foods were heavily exploited. Supported by other residue analysis data from Japan, our results show that the link between pottery and fishing was established in the Late Paleolithic and lasted well into the Holocene, despite environmental and socio-economic change. Cooking aquatic products in pottery represents an enduring social aspect of East Asian hunter-gatherers, a tradition based on a dependable technology for exploiting a sustainable resource in an uncertain and changing world.

This study examined relationships among individual demographics, environmental features (e.g., fast food outlet density, park land use) of residential neighborhoods and activity spaces, and weight-related behaviors (diet, physical activity). Participants’ movement was tracked for 7 days using global positioning systems (GPS). Two activity space measures (one standard deviation ellipse, daily path area) were derived from the GPS data. Activity spaces were generally larger than residential neighborhoods; environmental features of residential neighborhoods and activity spaces were weakly associated; and some activity space environmental features were related to dietary behaviors. Activity spaces may provide new insights into environmental influences on obesity-related behaviors.

Excavations at al-Basatin in Wadi Ziqlab, northern Jordan, have recovered evidence for an EB I occupation at the site, in addition to strata dating to the Late Neolithic and Classical periods. Arti...

During the summer and fall of 2002, an epidemic (223 cases) and epizootic of West Nile virus infections occurred in Chicago. Retrospective spatial analysis demonstrated that age-adjusted human case rates were three times higher inside geographic areas with high early-season crow deaths than outside these areas.

Objective: 1) Compare the outcomes of 2 surgical modalities used to treat hypopharyngeal diverticulum and esophageal stenosis at the Medical University of South Carolina (MUSC) and analyze the economic efficiency of each. 2) Compare the MUSC experience with statewide treatment in South Carolina (SC) Medicare patients.Method: Retrospective analysis was conducted of 50 patients treated at MUSC. The 2 approaches utilized were endoscopic laser diverticulotomy and transcervical open diverticulectomy with cricopharyngeal myotomy. SC Medicare data was collected for patients undergoing these procedures. Primary outcomes investigated were intraoperative complications, operative charge, hospital stay, and postoperative complications.Results: Statistically significant differences between the 2 operative groups at MUSC were observed in length of stay (1.08 days endoscopic group and 4.75 days transcervical open group; P > .0001) and operative charge (US $ 2842 endoscopic and US$ 3425 transcervical; P > .0001). The per...

Research in Wadi Ziqlab, Northern Jordan, has focused on the discovery and excavation of Late Neolithic sites in an attempt to understand its regional settlement system in the sixth millennium cal. BC. Previous evidence suggested that small hamlets or farmsteads may have characterized this settlement system, as represented at Tabaqat al-Bûma. Recent excavations at a site downstream, al-Basatîn, have revealed evidence for a settlement that was partly contemporary with Tabaqat al-Bûma and shared much of its material culture, but seems to have been markedly different in character. Whether for seasonal or some other reasons, its architecture as currently understood consisted of stone platforms and possibly tents, rather than the substantial houses found at the other site. Toward the end of the sixth millennium, like Tabaqat al-Bûma, it was abandoned, not to be reoccupied until Early Bronze I., Les recherches dans le Wadi Ziqlab (Jordanie) ont porté sur la découverte et la fouille de sites du Néolithique récent afin de comprendre le système régional d’implantation des sites au sixième millénaire cal. av. J.-C. Si les recherches précédentes ont suggéré que de petits hameaux ou fermes caractérisaient ce système, ainsi que l’illustre l’exemple de Tabaqat al-Bûma, les fouilles récentes du site d’al-Basatîn, localisé en aval, ont mis en évidence une occupation partiellement contemporaine de Tabaqat al-Bûma. Malgré les fortes similitudes de la culture matérielle avec celle de ce dernier site, al-Basatîn semble d’un caractère différent. Que ce soit pour des raisons saisonnières ou autres, son architecture, telle qu’elle est actuellement comprise, était constituée de plateformes en pierre et probablement de tentes, plutôt que de maisons véritables, comme celles connues à Tabaqat al-Bûma. Vers la fin du sixième millénaire, le site, à l’instar de Tabaqat al-Bûma, a été abandonné, puis réoccupé à partir du Bronze Ancien I., Kadowaki Seiji, Gibbs Kevin, Allentuck Adam, Banning Edward B. Late Neolithic Settlement in Wadi Ziqlab, Jordan: al-Basatîn. In: Paléorient, 2008, vol. 34, n°1. pp. 105-129.