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1. Spallation reaction study for the long-lived fission products in nuclear waste: Cross section measurements for 137Cs, 90Sr and 107Pd using inverse kinematics method

Author

Wang, He, Otsu, Hideaki, Sakurai, Hiroyoshi, Ahn, DeukSoon, Chiga, Nobuyuki, Doornenbal, Pieter, Fukuda, Naoki, Isobe, Tadaaki, Kubo, Toshiyuki, Kubono, Shigeru, Lorusso, Giusseppe, Söderström, Pär-Anders, Suzuki, Hiroshi, Takeda, Hiroyuki, Watanabe, Yasushi, Yoshida, Koichi, Matsuzaki, Teiichiro, Shimizu, Yohei, Sumikama, Toshiyuki, Uesaka, Meiko, Kawase, Shoichiro, Nakano, Keita, Watanabe, Yukinobu, Araki, Shouhei, Kin, Tadahiro, Takeuchi, Satoshi, Togano, Yasuhiro, Nakamura, Takashi, Kondo, Yosuke, Ozaki, Tomoyuki, Saito, Atsumi, Tsubota, Junichi, Aikawa, Masayuki, Makinaga, Ayano, Ando, Takashi, Koyama, Shunpei, Momiyama, Satoru, Nagamine, Shunsuke, Niikura, Megumi, Saito, Takeshi, Taniuchi, Ryo, Wimmer, Kathrin, Kawakami, Shunsuke, Maeda, Yukie, Yamamoto, Tatsuya, Shiga, Yoshiaki, Matsushita, Masafumi, Michimasa, Shin’ichiro, and Shimoura, Susumu

Published
2017
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2. Isotope-production cross sections of residual nuclei in proton- and deuteron-induced reactions on 93Zr at 50 MeV/u

Author

Nakano Keita, Watanabe Yukinobu, Kawase Shoichiro, Wang He, Otsu Hideaki, Sakurai Hiroyoshi, Chiga Nobuyuki, Suwa Junki, Sumikama Toshiyuki, Takeuchi Satoshi, Nakamura Takashi, Chikaato Kazuya, Takechi Maya, Koyama Shunpei, Soon Ahn Deuk, Baba Hidetada, Chen Sidong, Cortes Martha Liliana, Doornenbal Pieter, Fukuda Naoki, Hirayama Akihiro, Hosoda Ryohei, Isobe Tadaaki, Kawakami Shunsuke, Kondo Yosuke, Kubono Shigeru, Maeda Yukie, Masuoka Shoichiro, Michimasa Shin’ichiro, Murray Ian, Nakajima Ryo, Niikura Megumi, Ozaki Tomoyuki, Saito Atsumi, Saito Takeshi, Sato Hiromi, Shimizu Yohei, Shimoura Susumu, Soudo Yoshiki, Söderström Pär-Anders, Sun Xiaohui, Suzuki Daisuke, Suzuki Hiroshi, Takeda Hiroyuki, Togano Yasuhiro, Tomai Takato, Yamada Hiroki, Yasuda Masahiro, and Yoshida Koichi

Subjects
Physics, QC1-999
Abstract

The isotope-production cross sections in p- and d-induced reactions on 93Zr at approximately 50 MeV/nucleon were measured by using the inverse-kinematics method at RIKEN RI Beam Factory. The measured data were compared with the previous experimental 93Zr + p, d at 105 and 209 MeV/nucleon data. This comparison represents that the isotopic distribution of production cross sections at 51 MeV p-induced reaction is appreciably different from those at 105 and 209 MeV. On the other hand, these three data sets show that the shape of isotopic distribution is similar in the case of the d-induced reaction. Also, the measured production cross sections were compared with the theoretical model calculations with Particle and Heavy Ion Transport code System (PHITS) version 3.10 in order to investigate the reproducibility of the models implemented in PHITS. The calculations well reproduced the experimental data even in such low incident energy, while several discrepancies were still seen as in the p- and d-induced reactions at 105 and 209 MeV/nucleon.

Published
2020
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3. Spallation reaction study for long-lived fission products in nuclear waste

Author

Wang He, Otsu Hideaki, Sakurai Hiroyoshi, Ahn DeukSoon, Aikawa Masayuki, Ando Takashi, Araki Shouhei, Chen Sidong, Chiga Nobuyuki, Doornenbal Pieter, Fukuda Naoki, Isobe Tadaaki, Kawakami Shunsuke, Kawase Shoichiro, Kin Tadahiro, Kondo Yosuke, Koyama Shunpei, Kubono Shigeru, Maeda Yukie, Makinaga Ayano, Matsushita Masafumi, Matsuzaki Teiichiro, Michimasa Shin ichiro, Momiyama Satoru, Nagamine Shunsuke, Nakamura Takashi, Nakano Keita, Niikura Megumi, Ozaki Tomoyuki, Saito Atsumi, Saito Takeshi, Shiga Yoshiaki, Shikata Mizuki, Shimizu Yohei, Shimoura Susumu, Sumikama Toshiyuki, Söderstrom Pär-Anders, Suzuki Hiroshi, Takeda Hiroyuki, Takeuchi Satoshi, Taniuchi Ryo, Togano Yasuhiro, Tsubota Junichi, Uesaka Meiko, Watanabe Yasushi, Watanabe Yukinobu, Wimmer Kathrin, Yamamoto Tatsuya, and Yoshida Koichi

Subjects
Physics, QC1-999
Abstract

Spallation reaction for the long-lived fission product 107Pd has been studied for the purpose of nuclear waste transmutation. The isotopic-distribution cross sections on both proton and deuteron were obtained at 118 MeV/nucleon in inverse kinematics at the RIKEN Radioactive Isotope Beam Factory. A large cross-section difference was found between the proton and deuteron results for the light-mass products. The data were compared with the SPACS semi-empirical parameterization and the PHITS calculations including both the intranuclear cascade and evaporation processes. In addition, the potential of spallation reaction for transmutation of 107Pd is discussed.

Published
2020
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5. Cross sections for nuclide production in proton- and deuteron-induced reactions on 93Nb measured using the inverse kinematics method

Author

Nakano Keita, Watanabe Yukinobu, Kawase Shoichiro, Wang He, Otsu Hideaki, Sakurai Hiroyoshi, Takeuchi Satoshi, Togano Yasuhiro, Nakamura Takashi, Maeda Yukie, Ahn Deuk Soon, Aikawa Masayuki, Araki Shouhei, Chen Sidong, Chiga Nobuyuki, Doornenbal Pieter, Fukuda Naoki, Ichihara Takashi, Isobe Tadaaki, Kawakami Shunsuke, Kin Tadahiro, Kondo Yosuke, Koyama Shunpei, Kubo Toshiyuki, Kubono Shigeru, Kurokawa Meiko, Makinaga Ayano, Matsushita Masafumi, Matsuzaki Teiichiro, Michimasa Shin'ichiro, Momiyama Satoru, Nagamine Shunsuke, Niikura Megumi, Ozaki Tomoyuki, Saito Atsumi, Saito Takeshi, Shiga Yoshiaki, Shikata Mizuki, Shimizu Yohei, Shimoura Susumu, Sumikama Toshiyuki, Söderström Pär-Anders, Suzuki Hiroshi, Takeda Hiroyuki, Taniuchi Ryo, Tsubota Jun'ichi, Watanabe Yasushi, Wimmer Kathrin, Yamamoto Tatsuya, and Yoshida Koichi

Subjects
Physics, QC1-999
Abstract

Isotopic production cross sections were measured for proton- and deuteron-induced reactions on 93Nb by means of the inverse kinematics method at RIKEN Radioactive Isotope Beam Factory. The measured production cross sections of residual nuclei in the reaction 93Nb + p at 113 MeV/u were compared with previous data measured by the conventional activation method in the proton energy range between 46 and 249 MeV. The present inverse kinematics data of four reaction products (90Mo, 90Nb, 88Y, and 86Y) were in good agreement with the data of activation measurement. Also, the model calculations with PHITS describing the intra-nuclear cascade and evaporation processes generally well reproduced the measured isotopic production cross sections.

Published
2017
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6. Cross section measurement of residues produced in proton- and deuteron-induced spallation reactions on 93Zr at 105 MeV/u using the inverse kinematics method

Author

Kawase Shoichiro, Watanabe Yukinobu, Wang He, Otsu Hideaki, Sakurai Hiroyoshi, Takeuchi Satoshi, Togano Yasuhiro, Nakamura Takashi, Maeda Yukie, Ahn Deuk Soon, Aikawa Masayuki, Araki Shouhei, Chen Sidong, Chiga Nobuyuki, Doornenbal Pieter, Fukuda Naoki, Ichihara Takashi, Isobe Tadaaki, Kawakami Shunsuke, Kin Tadahiro, Kondo Yosuke, Koyama Shunpei, Kubo Toshiyuki, Kubono Shigeru, Kurokawa Meiko, Makinaga Ayano, Matsushita Masafumi, Matsuzaki Teiichiro, Michimasa Shin'ichiro, Momiyama Satoru, Nagamine Shunsuke, Nakano Keita, Niikura Megumi, Ozaki Tomoyuki, Saito Atsumi, Saito Takeshi, Shiga Yoshiaki, Shikata Mizuki, Shimizu Yohei, Shimoura Susumu, Sumikama Toshiyuki, Söderström Pär-Anders, Suzuki Hiroshi, Takeda Hiroyuki, Taniuchi Ryo, Tsubota Jun'ichi, Watanabe Yasushi, Wimmer Kathrin, Yamamoto Tatsuya, and Yoshida Koichi

Subjects
Physics, QC1-999
Abstract

Isotopic production cross sections in the proton- and deuteron-induced spallation reactions on 93Zr at an energy of 105 MeV/u were measured in inverse kinematics conditions for the development of realistic nuclear transmutation processes for long-lived fission products (LLFPs) with neutron and light-ion beams. The experimental results were compared to the PHITS calculations describing the intra-nuclear cascade and evaporation processes. Although an overall agreement was obtained, a large overestimation of the production cross sections for the removal of a few nucleons was seen. A clear shell effect associated with the neutron magic number N = 50 was observed in the measured isotopic production yields of Zr and Y isotopes, which can be reproduced reasonably by the PHITS calculation.

Published
2017
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7. Spallation reaction study for fission products in nuclear waste: Cross section measurements for 137Cs, 90Sr and 107Pd on proton and deuteron

Author

Wang He, Otsu Hideaki, Sakurai Hiroyoshi, Ahn DeukSoon, Aikawa Masayuki, Ando Takashi, Araki Shouhei, Chen Sidong, Chiga Nobuyuki, Doornenbal Pieter, Fukuda Naoki, Isobe Tadaaki, Kawakami Shunsuke, Kawase Shoichiro, Kin Tadahiro, Kondo Yosuke, Koyama Shupei, Kubono Shigeru, Maeda Yukie, Makinaga Ayano, Matsushita Masafumi, Matsuzaki Teiichiro, Michimasa Shinichiro, Momiyama Satoru, Nagamine Shunsuke, Nakamura Takashi, Nakano Keita, Niikura Megumi, Ozaki Tomoyuki, Saito Atsumi, Saito Takeshi, Shiga Yoshiaki, Shikata Mizuki, Shimizu Yohei, Shimoura Susumu, Sumikama Toshiyuki, Söderström Pär-Anders, Suzuki Hiroshi, Takeda Hiroyuki, Takeuchi Satoshi, Taniuchi Ryo, Togano Yasuhiro, Tsubota Junichi, Uesaka Meiko, Watanabe Yasushi, Watanabe Yukinobu, Wimmer Kathrin, Yamamoto Tatsuya, and Yoshida Koichi

Subjects
Physics, QC1-999
Abstract

Spallation reactions for the long-lived fission products 137Cs, 90Sr and 107Pd have been studied for the purpose of nuclear waste transmutation. The cross sections on the proton- and deuteron-induced spallation were obtained in inverse kinematics at the RIKEN Radioactive Isotope Beam Factory. Both the target and energy dependences of cross sections have been investigated systematically. and the cross-section differences between the proton and deuteron are found to be larger for lighter fragments. The experimental data are compared with the SPACS semi-empirical parameterization and the PHITS calculations including both the intra-nuclear cascade and evaporation processes.

Published
2017
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8. Isotope production in proton-, deuteron-, and carbon-induced reactions on Nb 93 at 113 MeV/nucleon

Author

Nakano, Keita, Watanabe, Yukinobu, Kawase, Shoichiro, Wang, He, Otsu, Hideaki, Sakurai, Hiroyoshi, Takeuchi, Satoshi, Togano, Yasuhiro, Nakamura, Takashi, Maeda, Yukie, Ahn, Deuk Soon, Aikawa, Masayuki, Araki, Shouhei, Chen, Sidong, Chiga, Nobuyuki, Doornenbal, Pieter, Fukuda, Naoki, Ichihara, Takashi, Isobe, Tadaaki, Kawakami, Shunsuke, Kin, Tadahiro, Kondo, Yosuke, Koyama, Shunpei, Kubo, Toshiyuki, Kubono, Shigeru, Uesaka, Meiko, Makinaga, Ayano, Matsushita, Masafumi, Matsuzaki, Teiichiro, Michimasa, Shin'ichiro, Momiyama, Satoru, Nagamine, Shunsuke, Niikura, Megumi, Ozaki, Tomoyuki, Saito, Atsumi, Saito, Takeshi, Shiga, Yoshiaki, Shikata, Mizuki, Shimizu, Yohei, Shimoura, Susumu, Sumikama, Toshiyuki, Söderström, Pär Anders, Suzuki, Hiroshi, Takeda, Hiroyuki, Taniuchi, Ryo, Tsubota, Jun'ichi, Watanabe, Yasushi, Wimmer, Kathrin, Yamamoto, Tatsuya, and Yoshida, Koichi

Abstract

Isotope-production cross sections for p-, d-, and C-induced spallation reactions on Nb93 at 113 MeV/nucleon were measured using the inverse-kinematics method employing secondary targets of CH2, CD2, and C. The measured cross sections for Mo90, Nb90, Y86,88 produced by p-induced reactions were found to be consistent with those measured by the conventional activation method. We performed benchmark tests of the reaction models INCL-4.6, JQMD, and JQMD-2.0 implemented in the Particle and Heavy Ion Transport code System (PHITS) and of the nuclear data libraries JENDL-4.0/HE, TENDL-2017, and ENDF/B-VIII.0. The model calculations also showed generally good agreement with the measured isotope-production cross sections for p-, d-, and C-induced reactions. It also turns out that, among the three nuclear data libraries, JENDL-4.0/HE provides the best agreement with the measured data for the p-induced reactions. We compared the present Nb93 data with the Zr93 data, that were measured previously by the same inverse kinematics method (Kawase et al., Prog. Theor. Exp. Phys. 2017, 093D03 (2017)2050-391110.1093/ptep/ptx110), with particular attention to the effect of neutron-shell closure on isotope production in p- and d-induced spallation reactions. The isotopic distributions of the measured production cross sections in the Zr93 data showed noticeable jumps at neutron number N=50 in the isotopic chains of ΔZ=0 and -1, whereas no such jump appeared in isotopic chain of ΔZ=0 in the Nb93 data. From INCL-4.6 + GEM calculations, we found that the jump formed in the evaporation process is smeared out by the intranuclear cascade component in Nb91 produced by the Nb93(p,p2n) and (d,d2n) reactions on Nb93. Moreover, for Nb93, the distribution of the element-production cross sections as a function of the change in proton number ΔZ is shifted to smaller ΔZ than for Zr93, because the excited Nb prefragments generated by the cascade process are more likely to emit protons than the excited Zr prefragments, due to the smaller proton-separation energies of the Nb isotopes.

Published
2019

9. Coulomb breakup reactions of 93,94 Zr in inverse kinematics

Author

Takeuchi, Satoshi, Nakamura, Takashi, Shikata, Mizuki, Togano, Yasuhiro, Kondo, Yosuke, Tsubota, Junichi, Ozaki, Tomoyuki, Saito, Atsumi, Otsu, Hideaki, Wang, He, Sakurai, Hiroyoshi, Watanabe, Yukinobu, Kawase, Shoichiro, Ahn, Deuk Soon, Aikawa, Masayuki, Ando, Takashi, Araki, Shohei, Chen, Sidong, Chiga, Nobuyuki, Doornenbal, Pieter, Ebata, Shuichiro, Fukuda, Naoki, Isobe, Tadaaki, Kawakami, Shunsuke, Kin, Tadahiro, Koyama, Shunpei, Kubono, Shigeru, Maeda, Yukie, Makinaga, Ayano, Matsushita, Masafumi, Matsuzaki, Teiichiro, Michimasa, Shin'ichiro, Momiyama, Satoru, Nagamine, Shunsuke, Nakano, Keita, Niikura, Megumi, Ogata, Kazuyuki, Saito, Takeshi, Shiga, Yoshiaki, Shimizu, Yohei, Shimoura, Susumu, Sumikama, Toshiyuki, Söderstrom, Pär Anders, Suzuki, Hiroshi, Takeda, Hiroyuki, Taniuchi, Ryo, Uesaka, Meiko, Watanabe, Yasushi, Wimmer, Kathrin, Yamamoto, Tatsuya, and Yoshida, Koichi

Subjects
Nuclear Theory, Nuclear Experiment
Abstract

Coulomb breakup reactions of 93,94 Zr have been studied in inverse kinematics at incident beam energies of about 200 MeV/nucleon in order to evaluate neutron capture reaction methods. The 93 Zr(n,γ) 94 Zr reaction is particularly important as a candidate nuclear transmutation reaction for the long-lived fission product 93 Zr in nuclear power plants. One- and two-neutron removal cross sections on Pb and C targets were measured to deduce the inclusive Coulomb breakup cross sections, 375 ± 29 (stat.) ± 30 (syst.) and 403 ± 26 (stat.) ± 31 (syst.) mb for 93 Zr and 94 Zr, respectively. The results are compared with estimates using the standard Lorentzian model and microscopic calculations. The results reveal a possible contribution of the pygmy dipole resonance or giant quadrupole resonance in the Coulomb breakup reactions of 94 Zr.

Published
2019

12. Coulomb breakup reactions of 93,94Zr in inverse kinematics

Author

Takeuchi, Satoshi, primary, Nakamura, Takashi, additional, Shikata, Mizuki, additional, Togano, Yasuhiro, additional, Kondo, Yosuke, additional, Tsubota, Junichi, additional, Ozaki, Tomoyuki, additional, Saito, Atsumi, additional, Otsu, Hideaki, additional, Wang, He, additional, Sakurai, Hiroyoshi, additional, Watanabe, Yukinobu, additional, Kawase, Shoichiro, additional, Ahn, DeukSoon, additional, Aikawa, Masayuki, additional, Ando, Takashi, additional, Araki, Shohei, additional, Chen, Sidong, additional, Chiga, Nobuyuki, additional, Doornenbal, Pieter, additional, Ebata, Shuichiro, additional, Fukuda, Naoki, additional, Isobe, Tadaaki, additional, Kawakami, Shunsuke, additional, Kin, Tadahiro, additional, Koyama, Shunpei, additional, Kubono, Shigeru, additional, Maeda, Yukie, additional, Makinaga, Ayano, additional, Matsushita, Masafumi, additional, Matsuzaki, Teiichiro, additional, Michimasa, Shin’ichiro, additional, Momiyama, Satoru, additional, Nagamine, Shunsuke, additional, Nakano, Keita, additional, Niikura, Megumi, additional, Ogata, Kazuyuki, additional, Saito, Takeshi, additional, Shiga, Yoshiaki, additional, Shimizu, Yohei, additional, Shimoura, Susumu, additional, Sumikama, Toshiyuki, additional, Söderstrom, Pär-Anders, additional, Suzuki, Hiroshi, additional, Takeda, Hiroyuki, additional, Taniuchi, Ryo, additional, Uesaka, Meiko, additional, Watanabe, Yasushi, additional, Wimmer, Kathrin, additional, Yamamoto, Tatsuya, additional, and Yoshida, Koichi, additional

Published
2019
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14. Spallation reaction study for the long-lived fission products in nuclear waste: Cross section measurements for 137 Cs, 90 Sr and 107 Pd using inverse kinematics method

Author

Wang, He, primary, Otsu, Hideaki, additional, Sakurai, Hiroyoshi, additional, Ahn, DeukSoon, additional, Chiga, Nobuyuki, additional, Doornenbal, Pieter, additional, Fukuda, Naoki, additional, Isobe, Tadaaki, additional, Kubo, Toshiyuki, additional, Kubono, Shigeru, additional, Lorusso, Giusseppe, additional, Söderström, Pär-Anders, additional, Suzuki, Hiroshi, additional, Takeda, Hiroyuki, additional, Watanabe, Yasushi, additional, Yoshida, Koichi, additional, Matsuzaki, Teiichiro, additional, Shimizu, Yohei, additional, Sumikama, Toshiyuki, additional, Uesaka, Meiko, additional, Kawase, Shoichiro, additional, Nakano, Keita, additional, Watanabe, Yukinobu, additional, Araki, Shouhei, additional, Kin, Tadahiro, additional, Takeuchi, Satoshi, additional, Togano, Yasuhiro, additional, Nakamura, Takashi, additional, Kondo, Yosuke, additional, Ozaki, Tomoyuki, additional, Saito, Atsumi, additional, Tsubota, Junichi, additional, Aikawa, Masayuki, additional, Makinaga, Ayano, additional, Ando, Takashi, additional, Koyama, Shunpei, additional, Momiyama, Satoru, additional, Nagamine, Shunsuke, additional, Niikura, Megumi, additional, Saito, Takeshi, additional, Taniuchi, Ryo, additional, Wimmer, Kathrin, additional, Kawakami, Shunsuke, additional, Maeda, Yukie, additional, Yamamoto, Tatsuya, additional, Shiga, Yoshiaki, additional, Matsushita, Masafumi, additional, Michimasa, Shin’ichiro, additional, and Shimoura, Susumu, additional

Published
2017
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15. Study of proton- and deuteron-induced spallation reactions on the long-lived fission product 93Zr at 105 MeV/nucleon in inverse kinematics

Author

Kawase, Shoichiro, primary, Nakano, Keita, additional, Watanabe, Yukinobu, additional, Wang, He, additional, Otsu, Hideaki, additional, Sakurai, Hiroyoshi, additional, Ahn, Deuk Soon, additional, Aikawa, Masayuki, additional, Ando, Takashi, additional, Araki, Shouhei, additional, Chen, Sidong, additional, Chiga, Nobuyuki, additional, Doornenbal, Pieter, additional, Fukuda, Naoki, additional, Isobe, Tadaaki, additional, Kawakami, Shunsuke, additional, Kin, Tadahiro, additional, Kondo, Yosuke, additional, Koyama, Shunpei, additional, Kubono, Shigeru, additional, Maeda, Yukie, additional, Makinaga, Ayano, additional, Matsushita, Masafumi, additional, Matsuzaki, Teiichiro, additional, Michimasa, Shin'ichiro, additional, Momiyama, Satoru, additional, Nagamine, Shunsuke, additional, Nakamura, Takashi, additional, Niikura, Megumi, additional, Ozaki, Tomoyuki, additional, Saito, Atsumi, additional, Saito, Takeshi, additional, Shiga, Yoshiaki, additional, Shikata, Mizuki, additional, Shimizu, Yohei, additional, Shimoura, Susumu, additional, Sumikama, Toshiyuki, additional, Söderström, Pär-Anders, additional, Suzuki, Hiroshi, additional, Takeda, Hiroyuki, additional, Takeuchi, Satoshi, additional, Taniuchi, Ryo, additional, Togano, Yasuhiro, additional, Tsubota, Jun'ichi, additional, Uesaka, Meiko, additional, Watanabe, Yasushi, additional, Wimmer, Kathrin, additional, Yamamoto, Tatsuya, additional, and Yoshida, Koichi, additional

Published
2017
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16. Spallation reaction study for the long-lived fission product 107Pd

Author

Wang, He, primary, Otsu, Hideaki, additional, Sakurai, Hiroyoshi, additional, Ahn, DeukSoon, additional, Aikawa, Masayuki, additional, Ando, Takashi, additional, Araki, Shouhei, additional, Chen, Sidong, additional, Nobuyuki, Chiga, additional, Doornenbal, Pieter, additional, Fukuda, Naoki, additional, Isobe, Tadaaki, additional, Kawakami, Shunsuke, additional, Kawase, Shoichiro, additional, Kin, Tadahiro, additional, Kondo, Yosuke, additional, Koyama, Shunpei, additional, Kubono, Shigeru, additional, Maeda, Yukie, additional, Makinaga, Ayano, additional, Matsushita, Masafumi, additional, Matsuzaki, Teiichiro, additional, Michimasa, Shin'ichiro, additional, Momiyama, Satoru, additional, Nagamine, Shunsuke, additional, Nakamura, Takashi, additional, Nakano, Keita, additional, Niikura, Megumi, additional, Ozaki, Tomoyuki, additional, Saito, Atsumi, additional, Saito, Takeshi, additional, Shiga, Yoshiaki, additional, Shikata, Mizuki, additional, Shimizu, Yohei, additional, Shimoura, Susumu, additional, Sumikama, Toshiyuki, additional, Söderström, Pär-Anders, additional, Suzuki, Hiroshi, additional, Takeda, Hiroyuki, additional, Takeuchi, Satoshi, additional, Taniuchi, Ryo, additional, Togano, Yasuhiro, additional, Tsubota, Junichi, additional, Uesaka, Meiko, additional, Watanabe, Yasushi, additional, Watanabe, Yukinobu, additional, Wimmer, Kathrin, additional, Yamamoto, Tatsuya, additional, and Yoshida, Koichi, additional

Published
2017
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21. Characterization of GABABReceptors Involved in Inhibition of Motility Associated With Acetylcholine Release in the Dog Small Intestine: Possible Existence of a Heterodimer of GABAB1and GABAB2Subunits

Author

Kawakami, Shunsuke, Uezono, Yasuhito, Makimoto, Noriaki, Enjoji, Akihito, Kaibara, Muneshige, Kanematsu, Takashi, and Taniyama, Kohtaro

Abstract

Characterization of the γ-aminobutyric acid (GABA)Breceptor involved in the motility of dog small intestine was analyzed by application of the microdialysis method to the small intestine of the whole body of the dog. The reverse transcription-polymerase chain reaction (RT-PCR) was used. Intraarterial administration of muscimol induced acceleration of motility associated with acetylcholine (ACh) release, these responses being antagonized by bicuculline. Intraarterial administration of baclofen induced inhibition of motility associated with ACh release, these responses being antagonized by CGP62349. GABA induced inhibition of motility associated with decrease in ACh release. CGP62349 alone induced acceleration of motility associated with increase in ACh release. RT-PCR revealed the presence of mRNAs for both subunits of GABABreceptor, GABAB1and GABAB2, in the dog small intestine, although GABAB1subunits were 6 isoforms of GABAB1(GABAB1(a)– GABAB1(g)), except GABAB1(d). Thus, the GABABreceptor located at cholinergic neurons as a heterodimer with subunits of GABAB1and GABAB2in the dog small intestine operates predominantly relative to the GABAAreceptor in physiological motility.

Published
2004
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22. Characterization of GABABReceptor in the Human Colon

Author

Uezono, Yasuhito, Kaibara, Muneshige, Hayashi, Hideki, Kawakami, Shunsuke, Enjoji, Akihito, Kanematsu, Takashi, and Taniyama, Kohtaro

Abstract

Characterization of the GABABreceptor in the human colon was performed by the reverse transcription-polymerase chain reaction (RT-PCR). mRNAs for both subunits of the GABABreceptor, GABAB1and GABAB2, were detected in the human colon. The GABAB1(e)isoform was detected in the human colon, but not in the brain, and the other isoforms, except GABAB1(d), were detected in both tissues. Thus, the GABABreceptor may be present as a heterodimer with subunits of GABAB1and GABAB2in the human colon.

Published
2004
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