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3 results on '"Karen Waddell"'

1. California's forest resources: Forest Inventory and Analysis, 2001–2010

Author

Sharon M. Stanton, Olaf Kuegler, Karen Waddell, and Glenn Christensen

Subjects
0106 biological sciences, Biomass (ecology), Forest inventory, 010504 meteorology & atmospheric sciences, Agroforestry, Logging, Forest management, Biodiversity, Forestry, 01 natural sciences, Invasive species, Inventory valuation, Geography, Disturbance (ecology), 010606 plant biology & botany, 0105 earth and related environmental sciences
Abstract

This report highlights key findings from the most recent (2001–2010) data collected by the Forest Inventory and Analysis program across all forest land in California, updating previously published findings from data collected from 2001 through 2005 (Christensen et al. 2008). We summarize and interpret basic resource information such as forest area, ownership, volume, biomass, and carbon stocks; forest structure and function topics such as biodiversity, forest age, and dead wood; disturbance information such as tree damage, fire, and invasive plants; and tree growth, mortality, and removals for timber products. Consistent sampling across different ownerships and forest management regimes now allow comparisons. The appendices provide details on inventory methods and design and include summary tables of data, with statistical error, for the suite of forest characteristics inventoried.

Published
2016
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2. Variable Efficiency of the Thymidine Kinase/Ganciclovir System in Human Glioblastoma Cell Lines: Implications for Gene Therapy

Author

Xiaozhuo Chen, Franck Sturtz, Karen Waddell, H. Ralph Snodgrass, Janine Shulok, Marc Sanson, Manuel Caruso, and Doros Platika

Subjects
Ganciclovir, Cell Survival, viruses, Genetic enhancement, Genetic Vectors, Biology, Transfection, Thymidine Kinase, Genes, Reporter, In vivo, Tumor Cells, Cultured, Genetics, Bystander effect, medicine, Animals, Humans, Simplexvirus, Cation Exchange Resins, Molecular Biology, Histocytochemistry, Gene Transfer Techniques, Genetic Therapy, beta-Galactosidase, Lipids, Molecular biology, Rats, Lipofectamine, Thymidine kinase, Cell culture, Molecular Medicine, Glioblastoma, medicine.drug
Abstract

The gene therapy strategy using the hsvl-thymidine kinase gene (TK) and ganciclovir (GCV) injections that has been used for treating human glioblastomas has not been as effective as expected after the first animal experiments. A better understanding of the different steps involved in this treatment, like gene transfer, gene expression, and sensitivity of the recipient cells, is needed. After proposing sensitivity criteria for the TK/GCV system and for the bystander effect, based on the levels of GCV that can be reached in vivo, we studied seven human glioblastoma cell lines (U87, U118, U251, SNB19, SNB75, SF295, SF539) for their sensitivity to the TK/GCV system. We also studied their in vitro bystander effect and their in vitro transfectability using LipofectAMINE as a transfection enhancer. Among six human glioblastoma cell lines stably transfected with the TK gene, five were sensitive to TK/GCV, and two had a good in vitro bystander effect. The in vitro transfectability of the cell lines tested was low (or = 1%) compared to that of an established animal cell line, C6 rat glioma, in which 20-30% of the cells can be transfected routinely. According to this in vitro analysis, most of the glioblastoma cell lines should be sensitive to the TK/GCV system, but there is an urgent need for agents to increase transfection efficiency.

Published
1997
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3. Subject Index Vol. 68, 1997

Author

Nicholas Ayache, Thomas M. Moriarty, G. Antoniadis, Bengt Linderoth, F. Lavenne, Roman Mirsky, Jacques Feldmar, C. Giorgi, Y. Muragaki, Ch. Matula, Michael J. Levy, J.R. Schvarcz, H. Goerzer, T. Taira, K. Ungersboeck, Serge Bracard, Björn A. Meyerson, D.E. Richardson, P. Charles Garell, Marc Sindou, Andrey V. Oblyapin, Audun Stubhaug, N. Hopf, F.E. Roux, E. Blondet, K. Roessler, Sang Sup Chung, Jamal M. Taha, Kazuhiko Nonomura, Igor O. Volkov, C.W. Dempsey, L. Mahfouf, Olof Flodmark, In Ki Mun, Tetsuo Kanno, C.R. Wirtz, Volker M. Tronnier, N. Tomiyama, Grégoire Malandain, W. Tschiltschke, N.L. Dorward, Jin Woo Chang, O. Alberti, Y. Terada, Matthew A. Howard, A. Ishida, D. Hellwig, Alf Sollevi, Per Kristian Eide, Andrey D. Anichkov, François Mauguière, Karen Waddell, M. Tremoulet, R. Andrews, Jeffrey Labuz, N.D. Kitchen, Eben Alexander, N. Soliman, A.T. Bergenheim, K. Takakura, Kirk Moffitt, J.H. Song, L. Casentini, M. Daniel Noh, Yong Gou Park, Catherine Fischer, Jacques Favre, Xiaozhuo Chen, Juriy Z. Polonskiy, M. Wallace, C. Vial, Yong Ko, Marshall Devor, Margareta B. Møller, G. Lanner, Blaine S. Nashold, R. Mah, Joseph A. Maldjian, J. Mukawa, D. Albe-Fessard, Kyung Hoe Lee, B. Abdennebi, Ron Kikinis, D.S. Casolino, E. Emery, Peter W. Carmel, C. Manelfe, Ruth Govrin-Lippmann, W. Wagner, Z. Harry Rappaport, P. Calvi, Luis Garcia-Larrea, Krupa Shanker, Eric Maurincomme, H.W.S. Schroeder, A. Perneczky, Y. Yoshii, J. Winters, K. Ericson, Joseph C.T. Chen, Luc Picard, Vadim Yakhnitsa, Mario M. Bonsanto, Michael Söderman, Vladimir B. Nizkovolos, Bernard Laurent, Vladimir A. Shoustin, J. Sabatier, I. Berry, Michael Schulder, H. Iseki, P.-Å. Ridderheim, Andreas Staubert, J.F. Kahamba, M.C. Spendel, Wen-Ching Liu, Erwan Kerrien, F. Colombo, K. Yamashiro, S.A. Rath, H. Bertalanffy, D.G.T. Thomas, A. Cavaggioni, R. Deinsberger, W.Th. Koos, P. Shamsgovara, J.P. Ranjeva, K. Seitz, Michael Knauth, Y. Lajat, Franck Sturtz, M. Zanusso, W. Dietrich, Friedrich K. Albert, L. Benes, Marie-Claude Gregoire, Stefan Kunze, William T. O'Connor, Peter McL. Black, René Anxionnat, Roland Peyron, D. Menegalli-Boggelli, Kazuhiro Katada, Joon Hyong Cho, Märta Segerdahl, M. Iwahara, Arcady V. Korzenev, M. Guerrero, Dennis E. Bullard, Doros Platika, Ferenc M. Jolesz, Laurent Launay, Kim J. Burchiel, H.-P. Richter, Th. Czech, Janine Shulok, Chul-Won Park, P. Grunert, Y. Masutani, Carl-Olav Stiller, A. Galvagni, Philip L. Gildenberg, M.R. Gaab, Mark A. Granner, K. Boulanouar, T. Dohi, M. Aichholzer, B.L. Bauer, T. Tanikawa, Jian-Guo Cui, Frédéric Bonnefoi, T. Nedjahi, W.R. Niendorf, R.R. Tasker, D. Heyman, J.C. Acevedo, E. Franchin, G. Palù, H. Ralph Snodgrass, Patrick Mertens, and R. Papasin

Subjects
medicine.medical_specialty, Index (economics), business.industry, Medicine, Surgery, Subject (documents), Medical physics, Neurology (clinical), business
Published
1997
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