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In quantum computing, error mitigation is a method to improve the results of an error-prone quantum processor by post-processing them on a classical computer. In this work, we improve the General Error Mitigation (GEM) method for scalability. GEM relies on the use of a matrix to represent the device error, which requires the execution of $2^{n+1}$ calibration circuits on the quantum hardware, where $n$ is the number of qubits. With our improved method, the number of calibration runs is independent of the number of qubits and depends only on the number of non-zero states in the output distribution. We run 1853 randomly generated circuits with widths between 2-7 qubits and depths between 10-140 gates on IBMQ superconducting devices. The experiments show that the mitigation works comparably well to GEM, while requiring a fraction of the calibration runs. Finally, an experiment to mitigate errors in a 100 qubit circuit demonstrates the scalable features of our method.

Quantum annealers conventionally use forward annealing to generate heuristic solutions. Reverse annealing can potentially generate better solutions but necessitates an appropriate initial state. Ways to find such states are generally unknown or highly problem dependent, offer limited success, and severely restrict the scope of reverse annealing. We use a general method that improves the overall solution quality and quantity by feeding reverse annealing with low-quality solutions obtained from forward annealing. An experimental demonstration of solving the graph coloring problem using the D-Wave quantum annealers shows that our method is able to convert invalid solutions obtained from forward annealing to at least one valid solution obtained after assisted reverse annealing for $57\%$ of $459$ random Erd\H{o}s-R\'enyi graphs. Our method significantly outperforms random initial states, obtains more unique solutions on average, and widens the applicability of reverse annealing. Although the average number of valid solutions obtained drops exponentially with the problem size, a scaling analysis for the graph coloring problem shows that our method effectively extends the computational reach of conventional forward annealing using reverse annealing.

Hybrid algorithms that combine quantum and classical resources have become commonplace in quantum computing. The variational quantum eigensolver (VQE) is routinely used to solve prototype problems. Currently, hybrid algorithms use no more than one kind of quantum computer connected to a classical computer. In this work, a novel triple-hybrid algorithm combines the effective use of a classical computer, a gate-based quantum computer, and a quantum annealer. The solution of a graph coloring problem found using a quantum annealer reduces the resources needed from a gate-based quantum computer to accelerate VQE by allowing simultaneous measurements within commuting groups of Pauli operators. We experimentally validate our algorithm by evaluating the ground state energy of H$_2$ using different IBM Q devices and the DWave Advantage system requiring only half the resources of standard VQE. Other larger problems we consider exhibit even more significant VQE acceleration. Several examples of algorithms are provided to further motivate a new field of multi-hybrid algorithms that leverage different kinds of quantum computers to gain performance improvements.

The variational quantum eigensolver (VQE) is a hybrid quantum-classical algorithm designed for current and near-term quantum devices. Despite its initial success, there is a lack of understanding involving several of its key aspects. There are problems with VQE that forbid a favourable scaling towards quantum advantage. In order to alleviate the problems, we propose and extensively test a quantum annealing inspired heuristic that supplements VQE. The improved VQE enables an efficient initial state preparation mechanism, in a recursive manner, for a quasi-dynamical unitary evolution. We conduct an in-depth scaling analysis of finding the ground state energies with increasing lattice sizes of the Heisenberg model, employing simulations of up to $40$ qubits that manipulate the complete state vector. For the current devices, we further propose a benchmarking toolkit using a mean-field model and test it on IBM Q devices. The improved VQE avoids barren plateaus, exits local minima, and works with low-depth circuits. Realistic gate execution times estimate a longer computational time to complete the same computation on a fully functional error-free quantum computer than on a quantum computer emulator implemented on a classical computer. However, our proposal can be expected to help accurate estimations of the ground state energies beyond $50$ qubits when the complete state vector can no longer be stored on a classical computer, thus enabling quantum advantage.

We present and analyze large-scale simulation results of a hybrid quantum-classical variational method to calculate the ground state energy of the anti-ferromagnetic Heisenberg model. Using a massively parallel universal quantum computer simulator, we observe that a low-depth-circuit ansatz advantageously exploits the efficiently preparable N\'{e}el initial state, avoids potential barren plateaus, and works for both one- and two-dimensional lattices. The analysis reflects the decisive ingredients required for a simulation by comparing different ans\"{a}tze, initial parameters, and gradient-based versus gradient-free optimizers. Extrapolation to the thermodynamic limit accurately yields the analytical value for the ground state energy, given by the Bethe ansatz. We predict that a fully functional quantum computer with 100 qubits can calculate the ground state energy with a relatively small error.

A general method to mitigate the effect of errors in quantum circuits is outlined. The method is developed in sight of characteristics that an ideal method should possess and to ameliorate an existing method which only mitigates state preparation and measurement errors. The method is tested on different IBM Q quantum devices, using randomly generated circuits with up to four qubits. A large majority of results show significant error mitigation.

We use discrete-event simulation to construct a subquantum model that can reproduce the quantum-theoretical prediction for the statistics of data produced by the Einstein-Podolsky-Rosen-Bohm experiment and an extension thereof. This model satisfies Einstein's criterion of locality and generates data in an event-by-event and cause-and-effect manner. We show that quantum theory can describe the statistics of the simulation data for a certain range of model parameters only.