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Purpose: To study the efficacy of Unani pharmacopoeial formulations viz Jawarish Zarooni, Majoon Kundur and Arq e Badiyaan as a treatment regimen in patients of overactive bladder and evaluate its effect on their quality of life. Materials and Method: This open labeled, single arm clinical study was conducted at Regional Research Institute of Unani Medicine (RRIUM), Srinagar. Patients fulfilling the inclusion criteria were enrolled in the study after signing the informed consent form. Jawarish Zarooni and Arq e Badiyaan were prescribed orally in the dosage of 7g and 30 ml respectively twice a day along with 7g single oral dose of Majoon Kundur. The duration of treatment was for 82 days. The patients were followed up on first, fourth, eighth and twelfth week. The results were expressed as Mean ± SEM. Symptomatic relief was assessed as percentage change in terms of presence of any symptom at baseline and at 82nd day. Results: Of the 36 patients enrolled 31 patients completed the study. The study demonstrated highly significant results (p<0.001) for nocturia and QOL as measured by patients perception of bladder control (PPBC), urinary incontinence and daytime micturation whereas very significant results were observed (p<0.01) for urgency. Conclusions: The Unani regimen was highly effective in managing the symptoms of OAB as the regimen has an array of phyto-constituents which demonstrated muscuranic antagonism, Ca2+ channel blocking, K channel opening, neuro-protection, neuro-toning and anxiety relieving properties. About 50% of the ingredients of the regimen were Ca2+ blockers. The synergism of these phyto-constituents probably made Ca2+ blockers effective in OAB. Keywords: Over Active Bladder, Ca2+ blocker, antimuscuranics

Background: Evolvulusalsinoidesis a well-known herbal drug possessing various promising medicinal properties described by prominent ancient scholars and also numerous preclinical and clinical researches has been performed, thus attestingit’s ample of pharmacological actions. So, thorough review of classical as well as contemporary literature has been executed on Evolvulusalsinoides to validate the pharmacological actions mentioned.           . Methods:For classical review,a comprehensive search of Unani literature is done and for latest research work on evolvulus, articles published in English language using PubMed, MEDLINE, and the Google scholar with search term including Sahnkpushpi, sankhaoli, Evolvulusalsinoides since 1991 to 2019 is done. Results: The search includescontemporary literature, ethnomedicinal sources and 35 research articles from 1992 to 2019 which further ascertains various pharmacological actions being mentioned in Unani literature including anti-inflammatory, anti-diarrheal, anti-helminthic, anti-convulsantand nootropicproperty of herb. Conclusion: The pharmacological action and therapeutic application of Shankhaholi/ Shankpushpiwhich ismentioned inclassical Unani literature are in accordance with latest research. Despite of having several researches on Evolvulusalsinoides there are still numerous indications mentioned in classical literature which are yet to be explored.   Keywords: Evolvulusalsinoides, herb, Unani, contemporary. &nbsp

With increased industrialization and urbanization, although a lot of progress has been achieved in the medical field leading to the increase in life expectancy. But simultaneously there has been an emergence of health and cosmetic related issues. Almost every individual is suffering from one or the other problem due to change in their lifestyle, dietary habits, stress, and other environmental factors such as pollution.  Hair fall, among various health and dermatology problems is most common cosmetic concern experienced by everyone at any point of their life with prevalence of 50% by the age of 35years which increases with advancing age in men and in women to 40% by the age of 50 years. Though it is not life threatening or debilitating condition but it has huge social and psychological impact as it is concerned with one’s appearance. In Unani System of Medicine, hair fall is classified as Intithār al-Sha‘r (Telogen Effluvium) and a number of local and oral drugs have been mentioned in classical Unani literature for the management of hair fall, but before starting pharmacotherapy Unani scholars recommend balance moderation in Asbab –e sitta zaruriyah (Six essential pre-requisite for maintaining health), to cut down dependency over pharmacotherapy.  In this paper, we have discussed the prevention of Intithār al-Sha‘r (Telogen Effluvium) by alteration in Asbab-e- Sitta Zaruriyah. Key words: Hair fall, Asbabe Sitta Zaruriyah, Telogen Effluvium &nbsp