Search

ICGEM is one of the five services coordinated by the International Gravity Field Service (IGFS) of the International Association of Geodesy (IAG)and has been serving to the community for almost two decades.Theservice providesthe scientific community with anarchive of static,temporal, and topographicglobal gravity field models of the Earth in a standardized format withthepossibility to assign DOIs.Furthermore, ICGEMprovidesinteractive calculation and visualisation services of gravity field functionals.Maintenance of such a service and development of new “demand-based” tools are of utmost importance to provide state-of-the-art products. In 2016, the ICGEM portal has been renewed to guarantee a smooth transition to future needs. The last remaining component of the previous ICGEM portal, the G3 Browser, has now been upgraded and integrated into the present ICGEM portal. The G3 Browser aims to compute time series of equivalent water height interactively and gives users the opportunity to compare different gravity model time series as well as impacts of corrections (e.g., GIA, C20) or filters. The G3 Browser is complementary to existing services such as GFZ’s GravIS portal which provides ready-to-use products based on GFZ and COST-G solutions with already applied corrections and filters. On the other hand, the ICGEM G3 Browser includes time series from further processing centres and institutions and different filtering options. This presentation includes the recent progress and how ICGEM and its components contribute to the gravity field related research and educational purposes in universities at graduate and undergraduate level.&nbsp, The 28th IUGG General Assembly (IUGG2023) (Berlin 2023)

Gravity determination at sea is essential for the definition of physical height systems at sea and adjacent coastal areas. Since 2017, four shipborne gravimetry campaigns were conducted using a Chekan-AM gyro stabilized platform gravimeter containing quartz spring sensors and an iMAR Inertial Measurement Unit serving as strapdown gravimeter. The comparison of both gravimeter types exposed complementary properties of both sensors. With proper maintenance, the gyro stabilized gravimeter shows a very stable linear drift, but its recordings are impaired by steering manoeuvres and harsh sea conditions. In contrast, the strapdown gravimeter recordings are typically reliable during the whole cruise. But with up to 80 hours, the durations of some of the analysed cruises were exceptionally challenging for strapdown measurements. Under these conditions, the accuracy of the strapdown recordings is slightly degraded due to non-linear sensor drift, although the major part of the drift can be eliminated by thermal calibration or stabilisation. Under smooth sea conditions at the Baltic Sea with cruise durations of less than 35 hours, a precision of 0.4 to 0.5 mGal was obtained for both individual gravimeter results. A combination of both gravimeter types using complementary high- and low-pass filtering provided drift reduction and the possibility of gravity determination during the entire cruise. In the latest campaign, two strapdown gravimeters were installed in addition to the gyro stabilized platform gravimeter allowing for a detailed comparison of the drift behaviour of all three gravimeters., The 28th IUGG General Assembly (IUGG2023) (Berlin 2023)

The almost 20-year-old ICGEM is one of the five services coordinated by the International Gravity Field Service (IGFS) of the International Association of Geodesy (IAG). Hosted by the GFZ Potsdam, it provides the scientific community with a comprehensive archive of static, temporal, and topographic global gravity field models (GGMs) of the Earth. Furthermore, ICGEM offers an interactive calculation and visualization service of gravity field functionals and tutorials on the theory. The current service cannot address the advancements in the field of gravity modelling and the wide range of applications of such models and their deliverables in Earth sciences. There is an immediate need to expand, modernise, and upgrade the existing database, research data and metadata included in all facets of the service. In this presentation, we will introduce an upcoming project that will improve, actualize and expand ICGEM with providing additional data and a sustainable infrastructure that follows the FAIR Principles (Findable, Accessible, Interoperable and Reusable). New gravity field related data of transdisciplinary importance (e.g., altimetry grids, DEMs) as well as new calculated gravity field functionals (e.g., isostatic gravity anomalies) and readily computed gravity functional grids will be added. The evaluation tools will be improved and data and metadata standards will be established. The new portal will be interlinked to other national and international research data initiatives (e.g., GGOS, NFDI4Earth). Finally, an improved public outreach strategy shall be developed. The realization of this project shall be done in close contact and communication with the international Earth Gravity Field community., The 28th IUGG General Assembly (IUGG2023) (Berlin 2023)

Data publications with digital object identifiers (DOI) are best practice for FAIR sharing data. Originally developed with the purpose of providing permanent access to (static) datasets described in scholarly literature, DOI today are more and more assigned to dynamic data. These DOIs are providing a citable and traceable reference of various types of sources (data, software, samples, equipment) and means of rewarding the originators and institutions. As a result of international groups, like the Coalition on Publishing Data in the Earth, Space and Environmental Sciences (COPDESS) and the Enabling FAIR Data project, data with assigned DOIs are fully citable in scholarly literature and many journals require the data underlying a publication to be available – even before accepting an article. Initial metrics for data citation allows data providers to demonstrate the value of the data collected by institutes and individual scientists.This is especially relevant for the geodesy, because, geodesy researchers are often much more involved in operational aspects and data provision than researchers in other fields might be. Therefore, compared to other scientific disciplines, geodesy researchers appear to be producing less “countable scientific” output. Consequently, geodesy data and equipment require a structured and well-documented mechanism which will enable citability, scientific recognition and reward that can be provided by assigning DOI to data and data products.To address these challenges and to identify opportunities for improved coordination and advocacy within the geodetic community, the International Association of Geodesy’s (IAG) Global Geodetic Observing System (GGOS) has established a Working Group on “Digital Object Identifiers (DOIs) for Geodetic Data Sets” in 2019. This Working Group is designated to establish best practices and advocate for the consistent implementation of DOIs across all IAG Services and in the greater geodetic community.The main objectives and activities of this working group are:(1) to identify what the community needs from consistent usage of DOIs for data in terms of being able to discover data, permanently cite data, and acknowledge the data providers (2) to develop recommendations for DOI minting strategies for different geodetic data types and granularity across IAG Services (static, dynamic, observational data, data products, combination products, networks) (3) to develop recommendations for a consistent method for data citation across all IAG Services, to support data providers, and to provide quantitative support detailing the use of geodetic datasets and other resources. (4) to develop recommendations for connecting metadata standards for data discovery (e.g. DataCite, ISO19115) with community metadata standards (GeodesyML, Station Logs) This presentation will provide an update on recent topics and first recommendations from the GGOS DOI Working Group.

The global gravitational potential generated by the attraction of the Earth’s topographic masses has been computed in spectral domain. The mass-source information is provided by the 1 arcmin resolution Earth2014 relief model and four averaged density values for rock, ocean, lake, and ice areas. The topography and bathymetry are split into confocal ellipsoidal shells of a defined thickness. Based on the provided mass-source information, the gravitational potential is expanded for each shell and then summed up to represent the complete gravitational potential of the topography (and bathymetry). In this contribution, we present the impact of different shell thicknesses to the model accuracy and computation time. Moreover, we expanded our topographic gravity field model up to spherical harmonic degree and order 5,494. Such short scale mass information represented by the topography can be used to complement high-resolution combined static gravity field models for the very high-frequency components of the gravity field. As an example, we enhanced (augmented) EIGEN-6C4 model with the high frequency components retrieved from the topographic model. The deflections of vertical values computed from the augmented model are compared w.r.t. ground truth observations in Germany, Southern Colorado and Iowa (USA) which suggest as expected a considerable improvement over rugged mountainous regions and comparable residuals in areas of moderate topography.

During the last few years, the determination of high-resolution global gravity field has gained momentum due to high-accuracy satellite-derived observations and development of forward gravity modelling. Forward modelling computes the global gravitational field from mass distribution sources instead of actual gravity measurements and helps improving and complementing the medium to high-frequency components of the global gravity field models. In this study, we approximate the global gravity potential of the Earth’s upper crust based on ellipsoidal approximation and a mass layer concept. Such an approach has an advantage of spectral methods and also avoids possible instabilities due to the use of a sequence of thin ellipsoidal shells. Lateral density within these volumetric shells bounded by confocal lower and upper shell ellipsoids is used in the computation of the ellipsoidal harmonic coefficients which are then transformed into spherical harmonic coefficients on the Earth’s surface in the final step. The main outcome of this research is a spectral representation of the gravitatioal potential of the Earth’s upper crust, computed up to degree and order 3660 in terms of spherical harmonic coefficients (ROLI_EllApprox_SphN_3660). We evaluate our methodology by comparing this model with other similar forward models in the literature which show sub-cm agreement in terms of geoid undulations. Finally, EIGEN-6C4 is augmented by ROLI_EllApprox_SphN_3660 and the gravity field functionals computed from the expanded model which has about 5 km half-wavelength spatial resolution are compared w.r.t. ground-truth data in different regions worldwide. Our investigations show that the contribution of the topographic model increases the agreement up to ~ 20% in the gravity value comparisons.

In this study, Al matrix composites consisting of different amounts of Zn, Cu, and Mg were produced using the powder metallurgy technique. In the alloying, powders were ball milled for 120 min via mechanical alloying. After alloying process, the powders were pressed at 800 MPa at room temperature. Sintering (2 h at 600 degrees C in argon atmosphere), solution treatment (2 h at 480 degrees C), and aging processes (3, 6, 9, and 12 h, respectively, at 120 degrees C) were applied to the samples. The hardness and tribo-metallurgy properties of the products were investigated. After sintering, the hardness values of the three alloys were close to each other; however, the solution treatment after sintering caused the hardness values to increase significantly. It was determined that the Al-2Zn-5Cu-4Mg alloy had the highest hardness increase with the 6-h aging heat treatment. The wear resistance of the materials in all the compositions had increased. The highest wear resistance and lowest friction coefficient were obtained for the Al-2Zn-5Cu-4Mg alloy with the 6-h aging heat treatment. C1 [Kaplan, Yavuz] Pamukkale Univ, Fac Technol, Dept Mech & Mfg Engn, Denizli, Turkey. [Aksoz, Sinan] Pamukkale Univ, Fac Technol, Dept Met & Mat Engn, Denizli, Turkey. [Ada, Hakan] Kastamonu Univ, Dept Mech Engn, Fac Engn & Architecture, Kastamonu, Turkey. [Ince, Emre; Ozsoy, Serkan] Kastamonu Univ, Inst Sci & Technol, Kastamonu, Turkey.

FAMOS (Finalizing Surveys for the Baltic Motorways of the Sea) is a recently run project which was supported by EU to improve the safety of ship navigation on the Baltic Sea. One task of FAMOS was to work on a common height reference for the Baltic Sea, the Baltic Sea Chart Datum 2000 (BSCD2000), which will be based on a new gravimetric geoid for this sea. The German institutions German Research Centre for Geosciences (GFZ), Federal Agency for Cartography and Geodesy (BKG), Federal Maritime and Hydrographic Agency (BSH) and Technical University of Darmstadt performed several marine gravimetry surveys to contribute to this project. The primary measurement equipment was GFZ’s Chekan-AM gravimeter. On two of these campaigns an iMAR strapdown inertial measurement unit (IMU) was used together with the Chekan. The data records from both instruments are of very good consistency. Since the FAMOS project ended ahead of the planned schedule already in 2019, finalization of the new chart Datum is now coordinated by the Chart Datum Working Group within the Baltic Sea Hydrographic Commission. It is planned to implement the new BSCD2000 by 2023.

Within the European Union FAMOS project, GFZ performed two gravimetry campaigns on commercial ferries in the Baltic Sea in 2017 and 2018. The nature of such “non-dedicated” campaigns is different from “dedicated” campaigns which are performed on research vessels with tracks planned according to gravity measurement needs. The non-dedicated campaigns use non-survey vessels (e.g. ferries) or survey vessels running for other purposes (e.g. hydrographic measurements). Measurements conducted on such conditions may require additional corrections besides the typical marine gravimetry corrections. We investigated two additional corrections, namely the vertical accelerations due to the motion of the ferry in the vertical direction and the dynamical effect due to the cross-coupling between horizontal and vertical acceleration components. To assess the usefulness of non-dedicated campaigns, we analysed gravity measurements collected on two commercial ferries and demonstrated that the standard processing without the above mentioned two corrections, as used in dedicated campaigns, already delivers good quality end products that fulfil the requirements of a typical marine gravimetry survey with an uncertainty of about 1 mGal for a much lower cost. Therefore, the data published in this contribution is a product of the same algorithm we use for dedicated campaign measurements. Based on our findings, we suggest that gravimetry campaigns on commercial ferries can be used to complement dedicated marine gravimetry campaigns and contribute to geodetic purposes.

Natural language processing which is an engineering field which is concerned with the design and implementation of computer systems whose main function is to analyze, understand, interpret and produce a natural language. Literature review was conducted using Turkish natural language studies documentation method. Documentation on the current method of examination to be reliable scientific research and thesis studies on natural language processing in Turkey were examined by scanning pages of the thesis of Higher Education. Evaluated in terms of the subjects of the study samples obtained as a result of the literature review Morphological analysis studies, syntactic analysis studies, semantic analysis studies and problem analysis criteria were determined and presented. Yilmaz Ince, E "Turkish Natural Language Processing Studies" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-4 | Issue-1 , December 2019, URL: https://www.ijtsrd.com/papers/ijtsrd29831.pdf

In this research, it is aimed to determine the success level of the students according to the answers given in the previous exams with TOPSIS method, to send the question to the related student by the authorized teacher according to the determined success level, to analyze the students periodical weekly monthly yearly performance with graphical data and to create a data bank and to determine the overall performance of the student. Developmental research technique was used, which is one of the design based research method derivatives including the design of educational tools. This study consists of question suggestion and question selection tool components. Adaptive question suggestion system perform generation, storage, classification, disclosure and publication of the content. The software has been successfully tested by 350 students and teachers by using 1000 questions prepared by the educator about the courses and subjects previously defined. As a result, it is seen that students check all the questions related to courses and subjects in the application database and submit the most appropriate question to the requestor in response to the question requests. Also it is observed that the TOPSIS algorithm quickly determined the desired number of questions from the question bank formed by the authorized teacher in accordance with the required criteria, and the process of creating a trial or subject test was performed successfully. ‡akir, A. | Yilmaz Ince, E. | Babanyyazova, Y. "Adaptive Question Recommendation System Based on Student Achievement" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-4 | Issue-1 , December 2019, URL: https://www.ijtsrd.com/papers/ijtsrd29789.pdf

Öz bulunamadı.

OBJECTIVE This study aimed to define the status of juvenile myelomonocytic leukemia (JMML) patients in Turkey in terms of time of diagnosis, clinical characteristics, mutational studies, clinical course, and treatment strategies. MATERIALS AND METHODS Data including clinical and laboratory characteristics and treatment strategies of JMML patients were collected retrospectively from pediatric hematology-oncology centers in Turkey. RESULTS Sixty-five children with JMML diagnosed between 2002 and 2016 in 18 institutions throughout Turkey were enrolled in the study. The median age at diagnosis was 17 months (min-max: 2-117 months). Splenomegaly was present in 92% of patients at the time of diagnosis. The median white blood cell, monocyte, and platelet counts were 32.9x109/L, 5.4x109/L, and 58.3x109/L, respectively. Monosomy 7 was present in 18% of patients. JMML mutational analysis was performed in 32 of 65 patients (49%) and PTPN11 was the most common mutation. Hematopoietic stem cell transplantation (HSCT) could only be performed in 28 patients (44%), the majority being after the year 2012. The most frequent reason for not performing HSCT was the inability to find a suitable donor. The median time from diagnosis to HSCT was 9 months (min-max: 2-63 months). The 5-year cumulative survival rate was 33% and median estimated survival time was 30±17.4 months (95% CI: 0-64.1) for all patients. Survival time was significantly better in the HSCT group (log-rank p=0.019). Older age at diagnosis (>2 years), platelet count of less than 40x109/L, and PTPN11 mutation were the factors significantly associated with shorter survival time. CONCLUSION Although there has recently been improvement in terms of definitive diagnosis and HSCT in JMML patients, the overall results are not satisfactory and it is necessary to put more effort into this issue in Turkey.

The determination of the global gravity field has gained momentum due to high accuracy satellite-derived observations and development of forward gravity modelling. Forward modelling computes the global gravitational field from mass distribution sources instead of actual gravity measurements and helps improving and complementing the medium to high frequency components of the global gravity field models. In this study, we approximate the global gravity potential of the Earth’s upper crust based on ellipsoidal approximation and a mass layer concept. Lateral density variations within a sequence of thin volumetric shells bounded by confocal lower and upper shell ellipsoids are used in the computation of the ellipsoidal harmonic coefficients which are then transformed into spherical harmonic coefficients on the Earth’s surface in the final step. The main outcome of this research is a spectral representation of the Earth’s upper crust’s gravitational potential, computed up to degree and order 3660 in terms spherical harmonic coefficients (ROLI_EllApprox_SphN_3660).

The 15 year old ICGEM is one of the five services coordinated by the International Gravity Field Service (IGFS)of the International Association of Geodesy (IAG). The aim of the ICGEM service is to provide the scientificcommunity with a state of the art archive of static and temporal global gravity field models of the Earth in astandardized format with a possibility to assign DOI number and develop interactive calculation and visualisationservices of gravity field functionals. Development and maintenance of such a unique platform is crucial for thescientific community in geodesy, geophysics, oceanography and climatology and has a positive impact in thegovernmental organisations and industrial practice. In this presentation, we will cover the maintenance, and the newfeatures and future plans of the ICGEM Service. New features include the calculation of gravity field functionalsat a list of distributed points and new topographic gravity field models whereas the future plans aim to meet theneeds of the scientific community.

22nd Congress of the European-Hematology-Association -- JUN 22-25, 2017 -- Madrid, SPAIN, WOS: 000404127006027, European Hematol Assoc

Kedi tırmık hastalığı (Cat Scratch Disease, CSD), kedilerde görülen ve bütün dünyada halk sağlığı problemi olan önemli bir zoonozdur. Bu çalışmada, prospektif kesitsel tarama ile pet ve başıboş kedilerdeki Bartonella henselae antikorlarının seroprevalansı ve bölge sağlık kuruluşlarının CSD kayıtları üzerinden hastalığın halk sağlığı açısından durumu araştırıldı. Total B. henselae antikorları, Selçuk Üniversitesi Veteriner Fakültesi Hayvan Hastanesi ve Konya Büyükşehir Belediyesi Geçici Hayvan Bakımevi'nden 93 pet ve 93 başıboş kediden alınan serum örneklerinde indirekt flörosan antikor testi (IFAT) ile değerlendirildi. B. henselae seropozitifliği pet ve başıboş kediler (sırasıyla, %26.88 ve %41.94) arasında yapılan karşılaştırmada, başıboş kedilerde belirgin şekilde yüksekti. Çalışmada, B. henselae' nın total seroprevalansı %34.41 olarak bulundu. Bölge sağlık örgütlerinin 1.5 yıllık kayıtlarına göre Konya bölgesinde toplamda 438 CSD vakası görüldüğü tespit edildi. Başıboş kedilerde B. henselae seroprevalansının yüksek olması, başıboş kedilerin vektörlerle yoğun temasta olmalarına yorumlandı. Sonuç olarak, Konya bölgesinde CSD'nin halk sağlığı açısından önemli bir risk olduğu gözlendi. Bu çerçevede bölgedeki CSD prevalansını azaltmak ve insanlara geçişini önlemek için tek sağlık konsepti içerisinde bilgilendirme, tedavi ve koruma çalışmaları yapılması gerektiği sonucuna varıldı, Cat Scratch Disease (CSD) is an important zoonosis seen in cats and a public health problem in all over the world. In this study, prospective cross-sectional serologic survey and examination of local health authority records for CSD, the seroprevalence of antibodies against Bartonella henselae in pet and stray cats, and its public health aspect were investigated. Total antibodies to B. henselae were evaluated by indirect fluorescent antibody test (IFAT) in serum samples taken from 93 pet cats and 93 stray cats from the Selcuk University Veterinary Faculty Animal Hospital and Konya Municipality Stray Animal Shelter. Percentages of pet cats and stray cats seropositive for antibodies against Bartonella henselae (26.88% and 41.94%, respectively) were significantly higher than percentages of pet cats. Total seroprevalence of Bartonella henselae was found to be 34.41% in the study. A total of 438 CSD cases were identified in the Konya region according to the data received from local health authority records in the previous 1.5 years . Stray cats have higher seroprevalences of antibodies against Bartonella henselae, but this likely was related to greater exposure to vectors of these organisms. In conclusion, it was observed that CSD is an important risk for public health in Konya region. Therefore in order to decrease CSD prevalence in this region and prevent transmission of the disease to humans, information, treatment and prevention studies must be carried out within the One Health concept

Öz bulunamadı.

A rhizosphere isolate Streptomyces sp. CAH29 was found to possess potent antibacterial and antifungal activity against a variety of test organisms. Based on 16S ribosomal ribonucleic acid sequence homology studies, this strain was found to be similar to Streptomyces stramineus (gene sequence similarity 99 %). The major bioactive metabolite produced by Streptomyces sp. CAH29 isolate was extracted, purified andidentified by nuclear magnetic resonance as tetrangomycin. This known anthraquinone-exhibited antimicrobial activity against Staphylococcus aureus, Streptococcus pyogenes, methicillin resistant Staphylococcus aureus and Candida albicans with inhibition zones of 14, 10, 12 and 8 mm, respectively. Docking results demonstrate that tetrangomycin has a similar mode of action and a comparable docking score to bind to the dehydrosqualene synthase (CrtM) enzyme of methicillin resistant Staphylococcus aureus compared to the current inhibitor. Hence, this suggests that tetrangomycin has a potential to be used as an anti-methicillin resistant Staphylococcus aureus agent. Tetrangomycin also showed moderate free radical scavenging activity with 1,1-diphenyl-2-picryl-hydrazil. Tetrangomycin apparently decreased all of the studied cytokine (pro-inflammatory: interleukin 1B, interleukin 2, tumor necrosis factor and interleukin L6 and anti-inflammatory: interleukin 10) expression levels at IC50 concentrations in A459 (adenocarcinomic human alveolar basal epithelial) and LNCAP (human prostate adenocarcinoma) cell lines. In addition, it reduced Caspase 8 and 3 mRNA levels in LNCAP and A549 cells. This study describes for the first time novel in vitro immunosuppressive function of tetrangomycin by reducing the transcription of cytokine genes.

Background: Surgical site infections (SSIs) are a threat to patient safety; however, there were no available data on SSI rates stratified by surgical procedure (SP) in Turkey. Methods: Between January 2005 and December 2011, a cohort prospective surveillance study on SSIs was conducted by the International Nosocomial Infection Control Consortium (INICC) in 20 hospitals in 16 Turkish cities. Data from hospitalized patients were registered using the Centers for Disease Control and Prevention (CDC) National Healthcare Safety Network (NHSN) methods and definitions for SSIs. Surgical procedures (SPs) were classified into 22 types according to International Classification of Diseases, Ninth Revision criteria. Results: We recorded 1879 SSIs, associated with 41,563 SPs (4.3%; 95% confidence interval, 4.3-4.7). Among the results, the SSI rate per type of SP compared with rates reported by the INICC and CDC NHSN were 11.9% for ventricular shunt (vs 12.9% vs 5.6%); 5.3% for craniotomy (vs 4.4% vs 2.6%); 4.9% for coronary bypass with chest and donor incision (vs 4.5 vs 2.9); 3.5% for hip prosthesis (vs 2.6% vs 1.3%), and 3.0% for cesarean section (vs 0.7% vs 1.8%). Conclusions: In most of the 22 types of SP analyzed, our SSI rates were higher than the CDC NHSN rates and similar to the INICC rates. This study advances the knowledge of SSI epidemiology in Turkey, allowing the implementation of targeted interventions. Copyright (C) 2015 by the Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. All rights reserved.

WOS: 000310091000001, The level structures of the N = 50 As-83, Ge-82, and Ga-81 isotones have been investigated by means of multi-nucleon transfer reactions. A first experiment was performed with the CLARA PRISMA setup to identify these nuclei. A second experiment was carried out with the GASP array in order to deduce the gamma-ray coincidence information. The results obtained on the high-spin states of such nuclei are used to test the stability of the N = 50 shell closure in the region of Ni-78 (Z = 28). The comparison of the experimental level schemes with the shell-model calculations yields an N = 50 energy gap value of 4.7(3) MeV at Z = 28. This value, in a good agreement with the prediction of the finite-range liquid-drop model as well as with the recent large-scale shell model calculations, does not support a weakening of the N = 50 shell gap down to Z = 28. (c) 2012 Elsevier B.V. All rights reserved., NSF [PHY0244389, PHY0555396]; European Commission within the Sixth Framework Programme through I3-EURONS [RII3-CT-2004-506065]; DGF (Germany) [DE 1516/-1]; Science and Technology Facilities Council [ST/G000689/1 NuSTAR, ST/F004052/1, ST/G000689/1, ST/J000108/1], We thank O. Sorlin for the useful discussions and the accelerator crews of LNL for the excellent support. A.F.L. acknowledges partial support of this work from NSF grants PHY0244389 and PHY0555396. This work has been partially supported by the European Commission within the Sixth Framework Programme through I3-EURONS (contract No. RII3-CT-2004-506065) and the DGF (Germany under contract No. DE 1516/-1).

Experimental liquid-liquid equilibria of the water-acetic acid-butyl acetate system were studied at temperatures of 298.15± 0.20, 303.15± 0.20 and 308.15± 0.20 K. Complete phase diagrams were obtained by determining solubility and tie-line data. The reliability of the experimental tie-line data was ascertained by using the Othmer and Tobias correlation. The UNIFAC group contribution method was used to predict the observed ternary liquid-liquid equilibrium (LLE) data. It was found that UNIFAC group interaction parameters used for LLE did not provide a good prediction. Distribution coefficients and separation factors were evaluated for the immiscibility region.

Background: Device-associated healthcare-acquired infections (DA-HAI) pose a threat to patient safety, particularly in the intensive care unit (ICU). We report the results of the International Infection Control Consortium (INICC) study conducted in Turkey from August 2003 through October 2012. Methods: A DA-HAI surveillance study in 63 adult, paediatric ICUs and neonatal ICUs (NICUs) from 29 hospitals, in 19 cities using the methods and definitions of the U.S. NHSN and INICC methods. Results: We collected prospective data from 94,498 ICU patients for 647,316 bed days. Pooled DA-HAI rates for adult and paediatric ICUs were 11.1 central line-associated bloodstream infections (CLABSIs) per 1000 central line (CL)-days, 21.4 ventilator-associated pneumonias (VAPs) per 1000 mechanical ventilator (MV)-days and 7.5 catheter-associated urinary tract infections (CAUTIs) per 1000 urinary catheter-days. Pooled DA-HAI rates for NICUs were 30 CLABSIs per 1000 CL-days, and 15.8 VAPs per 1000 MV-days. Extra length of stay (LOS) in adult and paediatric ICUs was 19.4 for CLABSI, 8.7 for VAP and 10.1 for CAUTI. Extra LOS in NICUs was 13.1 for patients with CLABSI and 16.2 for patients with VAP. Extra crude mortality was 12% for CLABSI, 19.4% for VAP and 10.5% for CAUTI in ICUs, and 15.4% for CLABSI and 10.5% for VAP in NICUs. Pooled device use (DU) ratios for adult and paediatric ICUs were 0.54 for MV, 0.65 for CL and 0.88 for UC, and 0.12 for MV, and 0.09 for CL in NICUs. The CLABSI rate was 8.5 per 1,000 CL days in the Medical Surgical ICUs included in this study, which is higher than the INICC report rate of 4.9, and more than eight times higher than the NHSN rate of 0.9. Similarly, the VAP and CAUTI rates were higher compared with U. S. NHSN (22.3 vs. 1.1 for VAP; 7.9 vs. 1.2 for CAUTI) and with the INICC report (22.3 vs. 16.5 in VAP; 7.9 vs. 5.3 in CAUTI). Conclusions: DA-HAI rates and DU ratios in our ICUs were higher than those reported in the INICC global report and in the US NHSN report.

Background: Device-associated healthcare-acquired infections (DA-HAI) pose a threat to patient safety, particularly in the intensive care unit (ICU). We report the results of the International Infection Control Consortium (INICC) study conducted in Turkey from August 2003 through October 2012. Methods: A DA-HAI surveillance study in 63 adult, paediatric ICUs and neonatal ICUs (NICUs) from 29 hospitals, in 19 cities using the methods and definitions of the U.S. NHSN and INICC methods. Results: We collected prospective data from 94,498 ICU patients for 647,316 bed days. Pooled DA-HAI rates for adult and paediatric ICUs were 11.1 central line-associated bloodstream infections (CLABSIs) per 1000 central line (CL)-days, 21.4 ventilator-associated pneumonias (VAPs) per 1000 mechanical ventilator (MV)-days and 7.5 catheter-associated urinary tract infections (CAUTIs) per 1000 urinary catheter-days. Pooled DA-HAI rates for NICUs were 30 CLABSIs per 1000 CL-days, and 15.8 VAPs per 1000 MV-days. Extra length of stay (LOS) in adult and paediatric ICUs was 19.4 for CLABSI, 8.7 for VAP and 10.1 for CAUTI. Extra LOS in NICUs was 13.1 for patients with CLABSI and 16.2 for patients with VAP. Extra crude mortality was 12% for CLABSI, 19.4% for VAP and 10.5% for CAUTI in ICUs, and 15.4% for CLABSI and 10.5% for VAP in NICUs. Pooled device use (DU) ratios for adult and paediatric ICUs were 0.54 for MV, 0.65 for CL and 0.88 for UC, and 0.12 for MV, and 0.09 for CL in NICUs. The CLABSI rate was 8.5 per 1,000 CL days in the Medical Surgical ICUs included in this study, which is higher than the INICC report rate of 4.9, and more than eight times higher than the NHSN rate of 0.9. Similarly, the VAP and CAUTI rates were higher compared with U.S. NHSN (22.3 vs. 1.1 for VAP; 7.9 vs. 1.2 for CAUTI) and with the INICC report (22.3 vs. 16.5 in VAP; 7.9 vs. 5.3 in CAUTI). Conclusions: DA-HAI rates and DU ratios in our ICUs were higher than those reported in the INICC global report and in the US NHSN report. © 2014 Leblebicioglu et al.

AMAÇ: Antiretroviral tedavinin (ART) kullanıma girmesiyle HIV'e bağlı ölümler azalmış, HIV/AIDS hastalarının yaşam kaliteleri artmıştır. Bununla beraber ART yan etkiler, tedaviye uyum problemleri, ilaç etkileşimleri ve direnç sorunu ile oldukça karmaşıktır. Bu çalışmada, polikliniğimizde takip edilen HIV/AIDS hastalarında ART'ye bağlı gelişen yan etki prevalansını belirlemeyi amaçladık.YÖNTEMLER: Enfeksiyon Hastalıkları ve Klinik Mikrobiyoloji HIV/AIDS Polikliniğinde Ocak 2006- Aralık 2011 tarihleri arasında takip edilen 260 hasta çalışma kapsamına alındı. Tedavi alan hastalarda gelişen yan etkilerin sıklığı, nedenleri ve sonuçları takip dosyalarının retrospektif incelemesi ile elde edildi.BULGULAR: Polikliniğimizden takipli 260 HIV/AIDS hastasının 171'i (%65.7) ART kullanmakta idi. ART altındaki olguların 123’ünde (%72) tedaviye bağlı yan etkiler gözlendi.En sık görülen yan etkiler nöropsikiyatrik komplikasyonlar (%30.4), ishal (%9.3) ve hiperlipidemi (%16.9) idi.. ART'ye bağlı yan etki gelişen tüm hastaların yalnızca 13 'ünün (%7.6) tedavisi değiştirildi.SONUÇ: ART ile ilişkili yan etki prevalansı yüksektir ve tedavi uyumunu bozabilmektedir. Bu nedenle ART altındaki HIV/AIDS hastalarında yan etkilerin yakın takibi son derece önemlidir.., OBJECTIVE: Since introduction of antiretroviral therapy (ART), HIV-related mortality has decreased and quality of life in HIV/AIDS patients has improved. ART is quite complicated due to side effects, drug interractions, adherence and drug resistance problems. In this study, we aimed to determine the side effects related to ART among HIV/AIDS patients followed by our Outpatient Clinic. METHODS: HIV/AIDS patients followed by the Infectious Diseases and Clinical Microbiology HIV/AIDS Outpatient Clinic between January 2006 and December 2011 were included in this study. Medical records were reviewed to determine the prevalence of side effects, causes and results in HIV/AIDS patients on ART.RESULTS: Of 260 HIV/AIDS patients 171(%65.7) were under ART. Of these, number of patients with ART related side effects 123 (%72). The most frequent side effects were neuropsychiatric complications (%30.4), diarrhea (%9.3) and hyperlipidemia (%16.9). ART regimen was changed in 13 (%7.6) of the patients had ART related side effects.CONCLUSION: The prevalence of ART related side effects are common and it may decrease drug adherence. Hence, close monitoring of ART toxicities in HIV/AIDS patients on ART assumes great importance.

Amaç: Antiretroviral tedavinin (ART) kullanıma girmesiyle HIV'e bağlı ölümler azalmış, HIV/AIDS hastalarının yaşam kaliteleri artmıştır. Bununla beraber ART yan etkiler, tedaviye uyum problemleri, ilaç etkileşimleri ve direnç sorunu ile oldukça karmaşıktır. Bu çalışmada, polikliniğimizde takip edilen HIV/AIDS hastalarında ART'ye bağlı gelişen yan etki prevalansını belirlemeyi amaçladık. Gereç ve yöntem: Enfeksiyon Hastalıkları ve Klinik Mikrobiyoloji HIV/AIDS Polikliniğinde Ocak 2006 - Aralık 2011 tarihleri arasında takip edilen 260 hasta çalışma kapsamına alındı. Tedavi alan hastalarda gelişen yan etkilerin sıklığı, nedenleri ve sonuçları takip dosyalarının retrospektif incelemesi ile elde edildi. Bulgular: Polikliniğimizden takipli 260 HIV/AIDS hastasının 171'i (%65.7) ART kullanmakta idi. ART altındaki olguların 123’ünde (%72) tedaviye bağlı yan etkiler gözlendi.?En sık görülen yan etkiler nöropsikiyatrik komplikasyonlar (%30.4), ishal (%9.3) ve hiperlipidemi (%16.9) idi. ART'ye bağlı yan etki gelişen tüm hastaların yalnızca 13 'ünün (%7.6) tedavisi değiştirildi. Sonuç: ART ile ilişkili yan etki prevalansı yüksektir ve tedavi uyumunu bozabilmektedir. Bu nedenle ART altındaki HIV/AIDS hastalarında yan etkilerin yakın takibi son derece önemlidir., Purpose: Since introduction of antiretroviral therapy (ART), HIV-related mortality has decreased and quality of life in HIV/AIDS patients has improved. ART is quite complicated due to side effects, drug interractions, adherence and drug resistance problems. In this study, we aimed to determine the side effects related to ART among HIV/AIDS patients followed by our outpatient clinic. Materials and methods: HIV/AIDS patients followed by the Infectious Diseases and Clinical Microbiology HIV/ AIDS Outpatient Clinic between January 2006 and December 2011 were included in this study. Medical records were reviewed to determine the prevalence of side effects, causes and results in HIV/AIDS patients on ART. Results: Of the 260 HIV/AIDS patients 171(65.7%) were under ART. Among these, the number of patients with ART related side effects was 123 (72.0%). The most frequent side effects were neuropsychiatric complications (30.4%), diarrhea (9.3%) and hyperlipidemia (16.9%). ART regimen was changed in 13 (7.6%) of the patients had ART related side effects. Conclusion: The prevalence of ART related side effects are common and it may decrease drug adherence. Hence, close monitoring of ART toxicities in HIV/AIDS patients on ART assumes great importance.

The results of a surveillance study conducted by the International Nosocomial Infection Control Consortium (INICC) from January 2004 through December 2009 in 422 intensive care units (ICUs) of 36 countries in Latin America, Asia, Africa, and Europe are reported. During the 6-year study period, using Centers for Disease Control and Prevention (CDC) National Healthcare Safety Network (NHSN; formerly the National Nosocomial Infection Surveillance system [NNIS]) definitions for device-associated health care-associated infections, we gathered prospective data from 313,008 patients hospitalized in the consortium's ICUs for an aggregate of 2,194,897 ICU bed-days. Despite the fact that the use of devices in the developing countries' ICUs was remarkably similar to that reported in US ICUs in the CDC's NHSN, rates of device-associated nosocomial infection were significantly higher in the ICUs of the INICC hospitals; the pooled rate of central line-associated bloodstream infection in the INICC ICUs of 6.8 per 1,000 central line-days was more than 3-fold higher than the 2.0 per 1,000 central line-days reported in comparable US ICUs. The overall rate of ventilator-associated pneumonia also was far higher (15.8 vs 3.3 per 1,000 ventilator-days), as was the rate of catheter-associated urinary tract infection (6.3 vs. 3.3 per 1,000 catheter-days). Notably, the frequencies of resistance of Pseudomonas aeruginosa isolates to imipenem (47.2% vs 23.0%), Klebsiella pneumoniae isolates to ceftazidime (76.3% vs 27.1%), Escherichia coli isolates to ceftazidime (66.7% vs 8.1%), Staphylococcus aureus isolates to methicillin (84.4% vs 56.8%), were also higher in the consortium's ICUs, and the crude unadjusted excess mortalities of device-related infections ranged from 7.3% (for catheter-associated urinary tract infection) to 15.2% (for ventilator-associated pneumonia). Copyright © 2012 by the Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. All rights reserved.

WOS: 000208479701301

This paper describes a framework for carrying out face recognition on a subset of standard color FERET database using two different subspace projection methods, namely PCA and Fisherfaces. At first, a rule based skin region segmentation algorithm is discussed and then details about eye localization and geometric normalization are given. The work achieves scale and rotation invariance by fixing the inter ocular distance to a selected value and by setting the direction of the eye-to-eye axis. Furthermore, the work also tries to avoid the small sample space (S3) problem by increasing the number of shots per subject through the use of one duplicate set per subject. Finally, performance analysis for the normalized global faces, the individual extracted features and for a multiple component combination are provided using a nearest neighbour classifier with Euclidean and/or Cosine distance metrics.

Experimental liquid-liquid equilibria of the water-acetic acid-butyl acetate system were studied at temperatures of 298.15± 0.20, 303.15± 0.20 and 308.15± 0.20 K. Complete phase diagrams were obtained by determining solubility and tie-line data. The reliability of the experimental tie-line data was ascertained by using the Othmer and Tobias correlation. The UNIFAC group contribution method was used to predict the observed ternary liquid-liquid equilibrium (LLE) data. It was found that UNIFAC group interaction parameters used for LLE did not provide a good prediction. Distribution coefficients and separation factors were evaluated for the immiscibility region.