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Your search keyword '"Huyskens, D."' showing total 9 results
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9 results on '"Huyskens, D."'

1. The potential impact of treatment variations on the results of radiotherapy of the internal mammary lymph node chain: a quality-assurance report on the dummy run of EORTC Phase III randomized trial 22922/10925 in Stage I--III breast cancer(1)

Author

Poortmans, P. M., Venselaar, J. L., Struikmans, H., Hurkmans, C. W., Davis, J. B., Huyskens, D., van Tienhoven, G., Vlaun, V., Lagendijk, J. J., Mijnheer, B. J., de Winter, K. A., van der Hulst, M. H., van den Bogaert, W. F., and Other departments

Abstract

PURPOSE: To present the results of the dummy run of the European Organization for Research and Treatment of Cancer (EORTC) trial investigating the role of adjuvant internal mammary and medial supraclavicular (IM-MS) irradiation in Stage I--III breast cancer. METHODS AND MATERIALS: All participating institutions were asked to produce a treatment plan without (Arm 1) and with (Arm 2) simultaneous IM-MS irradiation of 1 patient after mastectomy and of 1 patient after lumpectomy. Thirty-two dummy runs have been evaluated for compliance to protocol guidelines, with respect to treatment technique and dose prescription. RESULTS: A number of more or less important deviations in treatment setup and prescription have been found. The dose in the IM-MS region deviated significantly from the prescribed dose in 10% of the cases for Arm 1, and in 21% for Arm 2. Assuming a true 5% 10-year survival benefit from optimal IM-MS irradiation, an increase of only 3.8% will be found due to this suboptimal dose distribution. CONCLUSION: In the dummy run, a number of potential systematic protocol deviations that might lead to false-negative results were detected. By providing recommendations to the participating institutions, we expect to improve the interinstitutional consistency and to promote a high quality irradiation in all institutions participating in the trial

Published
2001

3. Breathing curve produced by magnetic sensors: Development and testing

Author

UCL - Autre, Remouchamps, VM, Destine, M, Beckers, B, Ansay, P, Iaisaouiyan, B, Huyskens, D, Salamon, E., De Neve, W, 47th Annual Meeting of the American-Society-for-Therapeutic-Radiology-and-Oncology, UCL - Autre, Remouchamps, VM, Destine, M, Beckers, B, Ansay, P, Iaisaouiyan, B, Huyskens, D, Salamon, E., De Neve, W, and 47th Annual Meeting of the American-Society-for-Therapeutic-Radiology-and-Oncology

Published
2005

6. Quality assurance in the EORTC phase III randomised trial 22922/10925 investigating the role of internal mammary and medial supraclavicular lymph node chain irradiation in stage I–III breast cancer: A report on the dummy run

Author

Poortmans, P.M, primary, Venselaar, J.L, additional, Struikmans, H, additional, Hurkmans, C, additional, Davis, B, additional, Huyskens, D, additional, van Tienhoven, G, additional, Vlaun, V, additional, Lagendijk, J.J, additional, Mijnheer, B, additional, De Winter, K.A, additional, Van der Hulst, M.H, additional, and Van de Bogaert, W.F, additional

Published
2000
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9. The potential impact of treatment variations on the results of radiotherapy of the internal mammary lymph node chain: a quality-assurance report on the dummy run of EORTC Phase III randomized trial 22922/10925 in Stage I--III breast cancer(1).

Author

Poortmans PM, Venselaar JL, Struikmans H, Hurkmans CW, Davis JB, Huyskens D, van Tienhoven G, Vlaun V, Lagendijk JJ, Mijnheer BJ, De Winter KA, Van der Hulst MH, and Van den Bogaert WF

Subjects
Breast Neoplasms pathology, Breast Neoplasms surgery, Female, Humans, Mastectomy, Mastectomy, Segmental, Neoplasm Staging, Physical Phenomena, Physics, Practice Guidelines as Topic, Quality Assurance, Health Care, Radiotherapy Dosage, Radiotherapy, Adjuvant standards, Breast Neoplasms radiotherapy, Lymphatic Irradiation standards
Abstract

Purpose: To present the results of the dummy run of the European Organization for Research and Treatment of Cancer (EORTC) trial investigating the role of adjuvant internal mammary and medial supraclavicular (IM-MS) irradiation in Stage I--III breast cancer., Methods and Materials: All participating institutions were asked to produce a treatment plan without (Arm 1) and with (Arm 2) simultaneous IM-MS irradiation of 1 patient after mastectomy and of 1 patient after lumpectomy. Thirty-two dummy runs have been evaluated for compliance to protocol guidelines, with respect to treatment technique and dose prescription., Results: A number of more or less important deviations in treatment setup and prescription have been found. The dose in the IM-MS region deviated significantly from the prescribed dose in 10% of the cases for Arm 1, and in 21% for Arm 2. Assuming a true 5% 10-year survival benefit from optimal IM-MS irradiation, an increase of only 3.8% will be found due to this suboptimal dose distribution., Conclusion: In the dummy run, a number of potential systematic protocol deviations that might lead to false-negative results were detected. By providing recommendations to the participating institutions, we expect to improve the interinstitutional consistency and to promote a high quality irradiation in all institutions participating in the trial.

Published
2001
Full Text
View/download PDF

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