160 results on '"Hutchins, Andrew P."'
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2. c-Jun as a one-way valve at the naive to primed interface
3. Restricting epigenetic activity promotes the reprogramming of transformed cells to pluripotency in a line-specific manner
4. In vitro generation of mouse morula-like cells
5. Disruption of neuronal RHEB signaling impairs oligodendrocyte differentiation and myelination through mTORC1-DLK1 axis
6. Species-specific rewiring of definitive endoderm developmental gene activation via endogenous retroviruses through TET1-mediated demethylation
7. A programmable system to methylate and demethylate N6-methyladenosine (m6A) on specific RNA transcripts in mammalian cells
8. The effects of sequencing depth on the assembly of coding and noncoding transcripts in the human genome
9. Single‐cell RNA sequencing reveals immune cell dysfunction in the peripheral blood of patients with highly aggressive gastric cancer
10. Identifying transposable element expression dynamics and heterogeneity during development at the single-cell level with a processing pipeline scTE
11. Single cells and transposable element heterogeneity in stem cells and development
12. c-JUN is a barrier in hESC to cardiomyocyte transition
13. JMJD3 acts in tandem with KLF4 to facilitate reprogramming to pluripotency
14. Transposable elements are regulated by context-specific patterns of chromatin marks in mouse embryonic stem cells
15. Pluripotency reprogramming by competent and incompetent POU factors uncovers temporal dependency for Oct4 and Sox2
16. c-JUN is a barrier in hESC to cardiomyocyte transition.
17. The homeodomain of Oct4 is a dimeric binder of methylated CpG elements
18. PCGF5 is required for neural differentiation of embryonic stem cells
19. Single-cell multiomics sequencing reveals the reprogramming defects in embryos generated by round spermatid injection
20. Metabolic and epigenetic dysfunctions underlie the arrest of in vitro fertilized human embryos in a senescent-like state
21. Transposable Elements in Pluripotent Stem Cells and Human Disease
22. CTCF functions as an insulator for somatic genes and a chromatin remodeler for pluripotency genes during reprogramming
23. Oct4 switches partnering from Sox2 to Sox17 to reinterpret the enhancer code and specify endoderm
24. Transposable element sequence fragments incorporated into coding and noncoding transcripts modulate the transcriptome of human pluripotent stem cells
25. β-Catenin safeguards the ground state of mouse pluripotency by strengthening the robustness of the transcriptional apparatus
26. Chromatin and Epigenetic Rearrangements in Embryonic Stem Cell Fate Transitions
27. DNA Damage Induces Dynamic Associations of BRD4/P-TEFb With Chromatin and Modulates Gene Transcription in a BRD4-Dependent and -Independent Manner
28. The IL-10/STAT3-mediated anti-inflammatory response: recent developments and future challenges
29. Systematic screening of CTCF binding partners identifies that BHLHE40 regulates CTCF genome-wide distribution and long-range chromatin interactions
30. β-Catenin safeguards the ground state of mousepluripotency by strengthening the robustness of the transcriptional apparatus
31. Selective recruitment of proteins to 5′ cap complexes during the growth cycle in Arabidopsis
32. DPre: computational identification of differentiation bias and genes underlying cell type conversions
33. An alternative CTCF isoform antagonizes canonical CTCF occupancy and changes chromatin architecture to promote apoptosis
34. Resolving Cell Fate Decisions during Somatic Cell Reprogramming by Single-Cell RNA-Seq
35. Computational Methods for Mapping, Assembly and Quantification for Coding and Non-coding Transcripts
36. Chromatin Accessibility Dynamics during iPSC Reprogramming
37. Kdm2b Regulates Somatic Reprogramming through Variant PRC1 Complex-Dependent Function
38. A sequential EMT-MET mechanism drives the differentiation of human embryonic stem cells towards hepatocytes
39. RNA Helicase DDX5 Inhibits Reprogramming to Pluripotency by miRNA-Based Repression of RYBP and its PRC1-Dependent and -Independent Functions
40. Generation of Human Liver Chimeric Mice with Hepatocytes from Familial Hypercholesterolemia Induced Pluripotent Stem Cells
41. Models of global gene expression define major domains of cell type and tissue identity
42. DPre: computational identification of differentiation bias and genes underlying cell type conversions.
43. Transcriptional Intricacies of Stem Cells
44. ADrosophila-centric view of protein tyrosine phosphatases
45. The p53-induced lincRNA-p21 derails somatic cell reprogramming by sustaining H3K9me3 and CpG methylation at pluripotency gene promoters
46. Transcriptional Pause Release Is a Rate-Limiting Step for Somatic Cell Reprogramming
47. Genome of Acanthamoeba castellanii highlights extensive lateral gene transfer and early evolution of tyrosine kinase signaling
48. Transient Activation of Mitoflashes Modulates Nanog at the Early Phase of Somatic Cell Reprogramming.
49. Unraveling the Human Embryonic Stem Cell Phosphoproteome
50. A Drosophila-centric view of protein tyrosine phosphatases.
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