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2. Dynamic 4D MRI for Characterization of Parathyroid Adenomas: Multiparametric Analysis.

Author

Hur, J, Bauer, A, Khan, R, Sepahdari, A, Inampudi, R, Guerrero, M, and Nael, Kambiz

Subjects
Adenoma, Adult, Aged, Contrast Media, Female, Humans, Logistic Models, Magnetic Resonance Imaging, Male, Middle Aged, Parathyroid Neoplasms, ROC Curve, Retrospective Studies, Sensitivity and Specificity
Abstract

BACKGROUND AND PURPOSE: The hypervascular nature of parathyroid adenomas can be explored by proper dynamic imaging to narrow the target lesions for surgical exploration. The purpose of this study was to establish MR perfusion characteristics of parathyroid adenomas to differentiate them from their mimics, such as subjacent thyroid tissue and cervical lymph nodes. MATERIALS AND METHODS: Preoperative high-spatial and -temporal resolution dynamic 4D contrast-enhanced MR imaging in 30 patients with surgically proved parathyroid adenomas was evaluated retrospectively. Using coregistered images, we placed ROIs over the parathyroid adenoma, thyroid gland, and a cervical lymph node (jugulodigastric) to obtain peak enhancement, time-to-peak, wash-in, and washout in each patient. Data were analyzed by logistic regression and analysis of variance. Receiver operating characteristic analysis was performed to determine the optimal parameters for determination of parathyroid adenomas versus thyroid tissue and cervical lymph nodes. RESULTS: Parathyroid adenomas showed significantly (P < .05) faster time-to-peak, higher wash-in, and higher washout compared with cervical lymph nodes and significantly (P < .05) higher peak enhancement, faster time-to-peak, higher wash-in, and higher washout compared with thyroid tissue. Logistic regression analysis indicated significant contribution from time-to-peak (P = .02), wash-in (P = .03), and washout (P = .008) for differentiation of parathyroid adenomas from thyroid and cervical lymph nodes. Using receiver operating characteristic analysis, we obtained the best diagnostic accuracy from a combination of time-to-peak/wash-in/washout in the differentiation of parathyroid adenomas versus lymph nodes (area under the curve, 0.96; sensitivity/specificity, 88%/90%) and in distinguishing parathyroid adenomas versus thyroid tissue (area under the curve, 0.96; sensitivity/specificity, 91%/95%). CONCLUSIONS: Dynamic 4D contrast-enhanced MR imaging can be used to exploit the hypervascular nature of parathyroid adenomas. Multiparametric MR perfusion can distinguish parathyroid adenomas from subjacent thyroid tissue or lymph nodes with diagnostic accuracies of 96%.

Published
2015

3. Fabrication of high performance MgB2 wires by an internal Mg diffusion process

Author

Hur, J. M., Togano, K., Matsumoto, A., Kumakura, H., Wada, H., and Kimura, K.

Subjects
Condensed Matter - Superconductivity, Condensed Matter - Other Condensed Matter
Abstract

We succeeded in the fabrication of high-Jc MgB2/Fe wires applying the internal Mg diffusion (IMD) process with pure Mg core and SiC addition. A pure Mg rod with 2 mm diameter was placed at the center of a Fe tube, and the space between Mg and Fe tube was filled with B powder or the powder mixture of B-(5mol%)SiC. The composite was cold worked into 1.2mm diameter wire and finally heat treated at temperatures above the melting point of Mg(~650oC). During the heat treatment liquid Mg infiltrated into B layer and reacted with B to form MgB2. X-ray diffraction analysis indicated that the major phase in the reacted layer is MgB2. SEM analysis shows that the density of MgB2 layer is higher than that of usual powder-in-tube(PIT) processed wires. The wires with 5mol% SiC addition heat treated at 670oC showed Jc values higher than 105A/cm2 in 8T and 41,000A/cm2 in 10T at 4.2K. These values are much higher than those of usual PIT processed wires even compared to the ones with SiC addition. Higher density of MgB2 layer obtained by the diffusion reaction is the major cause of this excellent Jc values., Comment: 7page, 6figures

Published
2007
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4. Global consortium for the classification of fungi and fungus-like taxa

Author

Hyde, K. D., Abdel-Wahab, M. A., Abdollahzadeh, J., Abeywickrama, P. D., Absalan, S., Afshari, N., Ainsworth, A. M., Akulov, O. Y., Aleoshin, V. V., Al-Sadi, A. M., Alvarado, P., Alves, A., Alves-Silva, G., Amalfi, M., Amira, Y., Amuhenage, T. B., Anderson, J. L., Antonín, V., Aouali, S., Aptroot, A., Apurillo, C. C. S., Araújo, J. P.M., Ariyawansa, H. A., Armand, A., Arumugam, E., Asghari, R., Assis, D. M.A., Atienza, V., Avasthi, S., Azevedo, E., Bahkali, A. H., Bakhshi, M., Banihashemi, Z., Bao, D. F., Baral, H. O., Barata, M., Barbosa, F. R., Barbosa, R. N., Barreto, R. W., Baschien, C., Belamesiatseva, D. B., Reuel, M. Bennett, Bera, I., Bezerra, J. D. P., Bezerra, J. L., Bhat, D. J., Bhunjun, C. S., Bianchinotti, M. V., Błaszkowski, J., Blondelle, A., Boekhout, T., Bonito, G., Boonmee, S., Boonyuen, N., Bregant, C., Buchanan, P., Bundhun, D., Burgaud, G., Burgess, T., Buyck, B., Cabarroi-Hernández, M., Cáceres, M. E. S., Caeiro, M. F., Cai, L., Cai, M. F., Calabon, M. S., Calaça, F. J. S., Callalli, M., Camara, M. P. S., Cano-Lira, J. F., Cantillo, T., Cao, B., Carlavilla, J. R., Carvalho, A., Castañeda-Ruiz, R. F., Castlebury, L., Castro-Jauregui, O., Catania, M. D., Cavalcanti, L. H., Cazabonne, J., Cedeño-Sanchez, M. L., Chaharmiri-Dokhaharani, S., Chaiwan, N., Chakraborty, N., Chaverri, P., Cheewangkoon, R., Chen, C., Chen, C. Y., Chen, K. H., Chen, J., Chen, Q., Chen, W. H., Chen, Y. P., Chethana, K. W. T., Coleine, C., Condé, T. O., Corazon-Guivin, M. A., Cortés-Pérez, A., Costa-Rezende, D. H., Courtecuisse, R., Crouch, J. A., Crous, P. W., Cui, B. K., Cui, Y. Y., da Silva, D. K. A., da Silva, G. A., da Silva, I. R., da Silva, R. M. F., da Silva Santos, A. C., Dai, D. Q., Dai, Y. C., Damm, U., Darmostuk, V., Zoha, Daroodi, Das, K., Davoodian, N., Davydov, E. A., Dayarathne, M. C., Decock, C., de Groot, M. D., De Kesel, A., de la Cruz, T. E. E., De Lange, R., Delgado, G., Denchev, C. M., Denchev, T. T., de Oliveira, N. T., de Silva, N. I., de Souza, F. A., Dentinger, B., Devadatha, B., Dianese, J. C., Dima, B., Diniz, A. G., Dissanayake, A. J., Dissanayake, L. S., Doğan, H. H., Doilom, M., Dolatabadi, S., Dong, W., Dong, Z. Y., Dos Santos, L. A., Drechsler-Santos, E. R., Du, T. Y., Dubey, M. K., Dutta, A. K., Egidi, E., Elliott, T. F., Elshahed, M. S., Erdoğdu, M., Ertz, D., Etayo, J., Evans, H. C., Fan, X. L., Fan, Y. G., Fedosova, A. G., Fell, J., Fernandes, I., Firmino, A. L., Fiuza, P. O., Flakus, A., de Souza, C. A.Fragoso, Frisvad, J. C., Fryar, S. C., Gabaldón, T., Gajanayake, A. J., Galindo, L. J., Gannibal, P. B., García, D., García-Sandoval, S. R., Garrido-Benavent, I., Garzoli, L., Gautam, A. K., Ge, Z. W., Gené, D. J., Gentekaki, E., Ghobad-Nejhad, M., Giachini, A. J., Gibertoni, T. B., Góes-Neto, A., Gomdola, D., de Farias, A. R. Gomes, Gorjón, S. P., Goto, B. T., Granados-Montero, M. M., Griffith, G. W., Groenewald, J. Z., Groenewald, M., Grossart, H. P., Gueidan, C., Gunarathne, A., Gunaseelan, S., Gusmão, L. F.P., Gutierrez, A. C., Guzmán-Dávalos, L., Haelewaters, D., Halling, R., Han, Y. F., Hapuarachchi, K. K., Harder, C. B., Harrington, T. C., Hattori, T., He, M. Q., He, S., He, S. H., Healy, R., Herández-Restrepo, M., Heredia, G., Hodge, K. T., Holgado-Rojas, M., Hongsanan, S., Horak, E., Hosoya, T., Houbraken, J., Huang, S. K., Huanraluek, N., Hur, J. S., Hurdeal, V. G., Hustad, V. P., Iotti, M., Iturriaga, T., Jafar, E., Janik, P., Jany, J. L., Jayalal, R. G.U., Jayasiri, S. C., Jayawardena, R. S., Jeewon, R., Jerônimo, G. H., Jesus, A. L., Jin, J., Johnston, P. R., Jones, E. B.G., Joshi, Y., Justo, A., Kaishian, P., Kakishima, M., Kaliyaperumal, M., Kang, G. P., Kang, J. C., Karakehian, J. M., Karimi, O., Karpov, S. A., Karunarathna, S. C., Kaufmann, M., Kemler, M., Kezo, K., Khyaju, S., Kirchmair, M., Kirk, P. M., Kitaura, M. J., Klawonn, I., Kolarik, M., Kong, A., Kuhar, F., Kukwa, M., Kumar, S., Kušan, I., Lado, C., Larsson, K. H., Latha, K. P.D., Lee, H. B., Leonardi, M., Leontyev, D. L., Lestari, A. S., Li, C. J.Y., Li, D. W., Li, H. Y., Li, L., Li, Q. R., Li, W. L., Li, Y., Li, Y. C., Liao, C. F., Liimatainen, K., Lim, Y. W., Lin, C. G., Linaldeddu, B. T., Linde, C. C., Linn, M. M., Liu, F., Liu, J. K., Liu, N. G., Liu, S., Liu, X. F., Liu, X. Z., Liu, Z. B., Lu, L., Lu, Y. Z., Luangharn, T., Luangsa-ard, J. J., Lumbsch, H. T., Lumyong, S., Luo, L., Luo, M., Luo, Z. L., Ma, J., Machado, A. R., Madagammana, A. D., Madrid, H., Magurno, F., Magyar, D., Mahadevan, N., Maharachchikumbura, S. S.N., Maimaiti, Y., Malosso, E., Manamgoda, D. S., Manawasinghe, I. S., Mapook, A., Marasinghe, D. S., Mardones, M., Marin-Felix, Y., Márquez, R., Masigol, H., Matočec, N., May, T. W., McKenzie, E. H.C., Meiras-Ottoni, A., Melo, R. F.R., Mendes-Alvarenga, R. L., Mendieta, S., Meng, Q. F., Menkis, A., Menolli, N., Mešić, A., Calvo, J. G.Meza, Mikhailov, K. V., Miller, S. L., Moncada, B., Moncalvo, J. M., Monteiro, J. S., Monteiro, M., Mora-Montes, H. M., Moreau, P. A., Mueller, G. M., Mukhopadyay, S., Murugadoss, R., Nagy, L. G., Najafiniya, M., Nanayakkara, C. M., Nascimento, C. C., Nei, Y., Neves, M. A., Neuhauser, S., Niego, A. G.T., Nilsson, R. H., Niskanen, T., Niveiro, N., Noorabadi, M. T., Noordeloos, M. E., Norphanphoun, C., Otaño, N. B.Nuñez, O’Donnell, R. P., Oehl, F., Olariaga, I., Orlando, O. P., Pang, K. L., Papp, V., Pawłowska, J., Peintner, U., Pem, D., Pereira, O. L., Perera, R. H., Perez-Moreno, J., Perez-Ortega, S., Péter, G., Phillips, A. J.L., Phonemany, M., Phukhamsakda, C., Phutthacharoen, K., Piepenbring, M., Pires-Zottarelli, C. L.A., Poinar, G., Pošta, A., Prieto, M., Promputtha, I., Quandt, C. A., Radek, R., Rahnama, K., Raj, K. N.A., Rajeshkumar, K. C., Rämä, T., Rambold, G., Ramírez-Cruz, V., Rasconi, S., Rathnayaka, A. R., Raza, M., Ren, G. C., Robledo, G. L., Rodriguez-Flakus, P., Ronikier, A., Rossi, W., Ryberg, M., Ryvarden, L. R., Salvador-Montoya, C. A., Samant, B., Samarakoon, B. C., Samarakoon, M. C., Sánchez-Castro, I., Sánchez-García, M., Sandoval-Denis, M., Santamaria, B., Santiago, A. L.C.M.A., Sarma, V. V., Savchenko, A., Savchenko, K., Saxena, R. K., Scholler, M., Schoutteten, N., Seifollahi, E., Selbmann, L., Selcuk, F., Senanayake, I. C., Shabashova, T. G., Shen, H. W., Shen, Y. M., Silva-Filho, A. G.S., Simmons, D. R., Singh, R., Sir, E. B., Song, C. G., Souza-Motta, C. M., Sruthi, O. P., Stadler, M., Stchigel, A. M., Stemler, J., Stephenson, S. L., Strassert, J. F.H., Su, H. L., Su, L., Suetrong, S., Sulistyo, B., Sun, Y. R., Svantesson, S., Sysouphanthong, P., Takamatsu, S., Tan, T. H., Tanaka, K., Tang, A. M.C., Tang, X., Tanney, J. B., Tavakol, N. M., Taylor, J. E., Taylor, P. W.J., Tedersoo, L., Tennakoon, D. S., Thamodini, G. K., Thines, M., Thiyagaraja, V., Thongklang, N., Tiago, P. V., Tian, Q., Tian, W. H., Tibell, L., Tibell, S., Tibpromma, S., Tkalčec, Z., Tomšovský, M., Toome-Heller, M., Torruella, G., Tsurykau, A., Udayanga, D., Ulukapi, M., Untereiner, W. A., Uzunov, B. A., Valle, L. G., Van Caenegem, W., Van den Wyngaert, S., Van Vooren, N., Velez, P., Verma, R. K., Vieira, L. C., Vieira, W. A.S., Vizzini, A., Walker, A., Walker, A. K., Wanasinghe, D. N., Wang, C. G., Wang, K., Wang, S. X., Wang, X. Y., Wang, Y., Wannasawang, N., Wartchow, F., Wei, D. P., Wei, X. L., White, J. F., Wijayawardene, N. N., Wijesinghe, S. N., Wijesundara, D. S.A., Wisitrassameewong, K., Worthy, F. R., Wu, F., Wu, G., Wu, H. X., Wu, N., Wu, W. P., Wurzbacher, C., Xiao, Y. P., Xiong, Y. R., Xu, B., Xu, L. J., Xu, R., Xu, T. M., Yakovchenko, L., Yan, J. Y., Yang, H. D., Yang, J., Yang, Z. L., Yang, Y. H., Yapa, N., Yasanthika, E., Youssef, N. H., Yu, F. M., Yu, Q., Yu, X. D., Yu, Y. X., Yu, Z. F., Yuan, H. S., Yuan, Y., Yurkov, A., Zafari, D., Zamora, J. C., Zare, R., Zeng, M., Zeng, N. K., Zeng, X. Y., Zhang, F., Zhang, H., Zhang, J. F., Zhang, J. Y., Zhang, Q. Y., Zhang, S. N., Zhang, W., Zhang, Y., Zhao, C. L., Zhao, H., Zhao, Q., Zhao, R. L., Zhou, L. W., Zhou, M., Zhurbenko, M. P., Zin, H. H., Zucconi, L., Hyde, K. D., Abdel-Wahab, M. A., Abdollahzadeh, J., Abeywickrama, P. D., Absalan, S., Afshari, N., Ainsworth, A. M., Akulov, O. Y., Aleoshin, V. V., Al-Sadi, A. M., Alvarado, P., Alves, A., Alves-Silva, G., Amalfi, M., Amira, Y., Amuhenage, T. B., Anderson, J. L., Antonín, V., Aouali, S., Aptroot, A., Apurillo, C. C. S., Araújo, J. P.M., Ariyawansa, H. A., Armand, A., Arumugam, E., Asghari, R., Assis, D. M.A., Atienza, V., Avasthi, S., Azevedo, E., Bahkali, A. H., Bakhshi, M., Banihashemi, Z., Bao, D. F., Baral, H. O., Barata, M., Barbosa, F. R., Barbosa, R. N., Barreto, R. W., Baschien, C., Belamesiatseva, D. B., Reuel, M. Bennett, Bera, I., Bezerra, J. D. P., Bezerra, J. L., Bhat, D. J., Bhunjun, C. S., Bianchinotti, M. V., Błaszkowski, J., Blondelle, A., Boekhout, T., Bonito, G., Boonmee, S., Boonyuen, N., Bregant, C., Buchanan, P., Bundhun, D., Burgaud, G., Burgess, T., Buyck, B., Cabarroi-Hernández, M., Cáceres, M. E. S., Caeiro, M. F., Cai, L., Cai, M. F., Calabon, M. S., Calaça, F. J. S., Callalli, M., Camara, M. P. S., Cano-Lira, J. F., Cantillo, T., Cao, B., Carlavilla, J. R., Carvalho, A., Castañeda-Ruiz, R. F., Castlebury, L., Castro-Jauregui, O., Catania, M. D., Cavalcanti, L. H., Cazabonne, J., Cedeño-Sanchez, M. L., Chaharmiri-Dokhaharani, S., Chaiwan, N., Chakraborty, N., Chaverri, P., Cheewangkoon, R., Chen, C., Chen, C. Y., Chen, K. H., Chen, J., Chen, Q., Chen, W. H., Chen, Y. P., Chethana, K. W. T., Coleine, C., Condé, T. O., Corazon-Guivin, M. A., Cortés-Pérez, A., Costa-Rezende, D. H., Courtecuisse, R., Crouch, J. A., Crous, P. W., Cui, B. K., Cui, Y. Y., da Silva, D. K. A., da Silva, G. A., da Silva, I. R., da Silva, R. M. F., da Silva Santos, A. C., Dai, D. Q., Dai, Y. C., Damm, U., Darmostuk, V., Zoha, Daroodi, Das, K., Davoodian, N., Davydov, E. A., Dayarathne, M. C., Decock, C., de Groot, M. D., De Kesel, A., de la Cruz, T. E. E., De Lange, R., Delgado, G., Denchev, C. M., Denchev, T. T., de Oliveira, N. T., de Silva, N. I., de Souza, F. A., Dentinger, B., Devadatha, B., Dianese, J. C., Dima, B., Diniz, A. G., Dissanayake, A. J., Dissanayake, L. S., Doğan, H. H., Doilom, M., Dolatabadi, S., Dong, W., Dong, Z. Y., Dos Santos, L. A., Drechsler-Santos, E. R., Du, T. Y., Dubey, M. K., Dutta, A. K., Egidi, E., Elliott, T. F., Elshahed, M. S., Erdoğdu, M., Ertz, D., Etayo, J., Evans, H. C., Fan, X. L., Fan, Y. G., Fedosova, A. G., Fell, J., Fernandes, I., Firmino, A. L., Fiuza, P. O., Flakus, A., de Souza, C. A.Fragoso, Frisvad, J. C., Fryar, S. C., Gabaldón, T., Gajanayake, A. J., Galindo, L. J., Gannibal, P. B., García, D., García-Sandoval, S. R., Garrido-Benavent, I., Garzoli, L., Gautam, A. K., Ge, Z. W., Gené, D. J., Gentekaki, E., Ghobad-Nejhad, M., Giachini, A. J., Gibertoni, T. B., Góes-Neto, A., Gomdola, D., de Farias, A. R. Gomes, Gorjón, S. P., Goto, B. T., Granados-Montero, M. M., Griffith, G. W., Groenewald, J. Z., Groenewald, M., Grossart, H. P., Gueidan, C., Gunarathne, A., Gunaseelan, S., Gusmão, L. F.P., Gutierrez, A. C., Guzmán-Dávalos, L., Haelewaters, D., Halling, R., Han, Y. F., Hapuarachchi, K. K., Harder, C. B., Harrington, T. C., Hattori, T., He, M. Q., He, S., He, S. H., Healy, R., Herández-Restrepo, M., Heredia, G., Hodge, K. T., Holgado-Rojas, M., Hongsanan, S., Horak, E., Hosoya, T., Houbraken, J., Huang, S. K., Huanraluek, N., Hur, J. S., Hurdeal, V. G., Hustad, V. P., Iotti, M., Iturriaga, T., Jafar, E., Janik, P., Jany, J. L., Jayalal, R. G.U., Jayasiri, S. C., Jayawardena, R. S., Jeewon, R., Jerônimo, G. H., Jesus, A. L., Jin, J., Johnston, P. R., Jones, E. B.G., Joshi, Y., Justo, A., Kaishian, P., Kakishima, M., Kaliyaperumal, M., Kang, G. P., Kang, J. C., Karakehian, J. M., Karimi, O., Karpov, S. A., Karunarathna, S. C., Kaufmann, M., Kemler, M., Kezo, K., Khyaju, S., Kirchmair, M., Kirk, P. M., Kitaura, M. J., Klawonn, I., Kolarik, M., Kong, A., Kuhar, F., Kukwa, M., Kumar, S., Kušan, I., Lado, C., Larsson, K. H., Latha, K. P.D., Lee, H. B., Leonardi, M., Leontyev, D. L., Lestari, A. S., Li, C. J.Y., Li, D. W., Li, H. Y., Li, L., Li, Q. R., Li, W. L., Li, Y., Li, Y. C., Liao, C. F., Liimatainen, K., Lim, Y. W., Lin, C. G., Linaldeddu, B. T., Linde, C. C., Linn, M. M., Liu, F., Liu, J. K., Liu, N. G., Liu, S., Liu, X. F., Liu, X. Z., Liu, Z. B., Lu, L., Lu, Y. Z., Luangharn, T., Luangsa-ard, J. J., Lumbsch, H. T., Lumyong, S., Luo, L., Luo, M., Luo, Z. L., Ma, J., Machado, A. R., Madagammana, A. D., Madrid, H., Magurno, F., Magyar, D., Mahadevan, N., Maharachchikumbura, S. S.N., Maimaiti, Y., Malosso, E., Manamgoda, D. S., Manawasinghe, I. S., Mapook, A., Marasinghe, D. S., Mardones, M., Marin-Felix, Y., Márquez, R., Masigol, H., Matočec, N., May, T. W., McKenzie, E. H.C., Meiras-Ottoni, A., Melo, R. F.R., Mendes-Alvarenga, R. L., Mendieta, S., Meng, Q. F., Menkis, A., Menolli, N., Mešić, A., Calvo, J. G.Meza, Mikhailov, K. V., Miller, S. L., Moncada, B., Moncalvo, J. M., Monteiro, J. S., Monteiro, M., Mora-Montes, H. M., Moreau, P. A., Mueller, G. M., Mukhopadyay, S., Murugadoss, R., Nagy, L. G., Najafiniya, M., Nanayakkara, C. M., Nascimento, C. C., Nei, Y., Neves, M. A., Neuhauser, S., Niego, A. G.T., Nilsson, R. H., Niskanen, T., Niveiro, N., Noorabadi, M. T., Noordeloos, M. E., Norphanphoun, C., Otaño, N. B.Nuñez, O’Donnell, R. P., Oehl, F., Olariaga, I., Orlando, O. P., Pang, K. L., Papp, V., Pawłowska, J., Peintner, U., Pem, D., Pereira, O. L., Perera, R. H., Perez-Moreno, J., Perez-Ortega, S., Péter, G., Phillips, A. J.L., Phonemany, M., Phukhamsakda, C., Phutthacharoen, K., Piepenbring, M., Pires-Zottarelli, C. L.A., Poinar, G., Pošta, A., Prieto, M., Promputtha, I., Quandt, C. A., Radek, R., Rahnama, K., Raj, K. N.A., Rajeshkumar, K. C., Rämä, T., Rambold, G., Ramírez-Cruz, V., Rasconi, S., Rathnayaka, A. R., Raza, M., Ren, G. C., Robledo, G. L., Rodriguez-Flakus, P., Ronikier, A., Rossi, W., Ryberg, M., Ryvarden, L. R., Salvador-Montoya, C. A., Samant, B., Samarakoon, B. C., Samarakoon, M. C., Sánchez-Castro, I., Sánchez-García, M., Sandoval-Denis, M., Santamaria, B., Santiago, A. L.C.M.A., Sarma, V. V., Savchenko, A., Savchenko, K., Saxena, R. K., Scholler, M., Schoutteten, N., Seifollahi, E., Selbmann, L., Selcuk, F., Senanayake, I. C., Shabashova, T. G., Shen, H. W., Shen, Y. M., Silva-Filho, A. G.S., Simmons, D. R., Singh, R., Sir, E. B., Song, C. G., Souza-Motta, C. M., Sruthi, O. P., Stadler, M., Stchigel, A. M., Stemler, J., Stephenson, S. L., Strassert, J. F.H., Su, H. L., Su, L., Suetrong, S., Sulistyo, B., Sun, Y. R., Svantesson, S., Sysouphanthong, P., Takamatsu, S., Tan, T. H., Tanaka, K., Tang, A. M.C., Tang, X., Tanney, J. B., Tavakol, N. M., Taylor, J. E., Taylor, P. W.J., Tedersoo, L., Tennakoon, D. S., Thamodini, G. K., Thines, M., Thiyagaraja, V., Thongklang, N., Tiago, P. V., Tian, Q., Tian, W. H., Tibell, L., Tibell, S., Tibpromma, S., Tkalčec, Z., Tomšovský, M., Toome-Heller, M., Torruella, G., Tsurykau, A., Udayanga, D., Ulukapi, M., Untereiner, W. A., Uzunov, B. A., Valle, L. G., Van Caenegem, W., Van den Wyngaert, S., Van Vooren, N., Velez, P., Verma, R. K., Vieira, L. C., Vieira, W. A.S., Vizzini, A., Walker, A., Walker, A. K., Wanasinghe, D. N., Wang, C. G., Wang, K., Wang, S. X., Wang, X. Y., Wang, Y., Wannasawang, N., Wartchow, F., Wei, D. P., Wei, X. L., White, J. F., Wijayawardene, N. N., Wijesinghe, S. N., Wijesundara, D. S.A., Wisitrassameewong, K., Worthy, F. R., Wu, F., Wu, G., Wu, H. X., Wu, N., Wu, W. P., Wurzbacher, C., Xiao, Y. P., Xiong, Y. R., Xu, B., Xu, L. J., Xu, R., Xu, T. M., Yakovchenko, L., Yan, J. Y., Yang, H. D., Yang, J., Yang, Z. L., Yang, Y. H., Yapa, N., Yasanthika, E., Youssef, N. H., Yu, F. M., Yu, Q., Yu, X. D., Yu, Y. X., Yu, Z. F., Yuan, H. S., Yuan, Y., Yurkov, A., Zafari, D., Zamora, J. C., Zare, R., Zeng, M., Zeng, N. K., Zeng, X. Y., Zhang, F., Zhang, H., Zhang, J. F., Zhang, J. Y., Zhang, Q. Y., Zhang, S. N., Zhang, W., Zhang, Y., Zhao, C. L., Zhao, H., Zhao, Q., Zhao, R. L., Zhou, L. W., Zhou, M., Zhurbenko, M. P., Zin, H. H., and Zucconi, L.

Abstract

The Global Consortium for the Classification of Fungi and fungus-like taxa is an international initiative of more than 550 mycologists to develop an electronic structure for the classification of these organisms. The members of the Consortium originate from 55 countries/regions worldwide, from a wide range of disciplines, and include senior, mid-career and early-career mycologists and plant pathologists. The Consortium will publish a biannual update of the Outline of Fungi and fungus-like taxa, to act as an international scheme for other scientists. Notes on all newly published taxa at or above the level of species will be prepared and published online on the Outline of Fungi website (https://www.outlineoffungi.org/), and these will be finally published in the biannual edition of the Outline of Fungi and fungus-like taxa. Comments on recent important taxonomic opinions on controversial topics will be included in the biannual outline. For example, 'to promote a more stable taxonomy in Fusarium given the divergences over its generic delimitation', or 'are there too many genera in the Boletales?' and even more importantly, 'what should be done with the tremendously diverse 'dark fungal taxa?' There are undeniable differences in mycologists' perceptions and opinions regarding species classification as well as the establishment of new species. Given the pluralistic nature of fungal taxonomy and its implications for species concepts and the nature of species, this consortium aims to provide a platform to better refine and stabilise fungal classification, taking into consideration views from different parties. In the future, a confidential voting system will be set up to gauge the opinions of all mycologists in the Consortium on important topics. The results of such surveys will be presented to the International Commission on the Taxonomy of Fungi (ICTF) and the Nomenclature Committee

Published
2023

5. P02.01.B The telomere maintenance mechanism spectrum and its dynamics in gliomas

Author

Kim, S, primary, Chowdhury, T, additional, Yu, H, additional, Choi, S, additional, Kim, K, additional, Kang, H, additional, Lee, J, additional, Lee, S, additional, Won, J, additional, Kim, M, additional, Kim, J, additional, Kim, Y, additional, Kim, T, additional, Phi, J, additional, Shin, Y, additional, Ku, J, additional, Yun, H, additional, Lee, H, additional, Kim, D, additional, Hur, J K, additional, Park, S, additional, Kim, S, additional, and Park, C, additional

Published
2022
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7. Role of Gasdermins in the Biogenesis of Apoptotic Cell–Derived Exosomes

Author

Yoo Hs, Shahriyar Sa, Jaesik Kim, Young-Jin Kim, Mustajab T, Kang Dw, Hur J, Chwae Y, Kim Dy, and Choi Da

Subjects
Cytosol, medicine.anatomical_structure, Endosome, Chemistry, Cell, medicine, Pyroptosis, Grancalcin, Microvesicles, Biogenesis, Cell biology, Proinflammatory cytokine
Abstract

The gasdermins, GSDMA, GSDMB, GSDMC, GSDMD, DFNA5, and DFNB59, are a family of pore-forming proteins that has recently been suggested to play a central role in the pyroptosis and the release of inflammatory cytokines. Here, we describe the novel roles of gasdermins in the biogenesis of apoptotic cell–derived exosomes. In apoptotic cells, GADMA, GSDMC, GSDMD, and DFNA5 increased the release of ApoExos, and both their full-length and cleaved forms were localized in the exosomal membrane. GSDMB and DFNB59, on the other hand, negatively affected the release of ApoExos. The caspase-mediated cleavage of gasdermins, especially DFNA5, is suggested to enable cytosolic Ca2+ to flow through endosomal pores and thus increase the biogenesis of ApoExos. In addition, the DFNA5-meidiated biogenesis of ApoExos depended on the ESCRT-III complex and endosomal recruitment of Ca2+-dependent proteins: annexins A2 and A7, the PEF domain family proteins sorcin and grancalcin, and the Bro1 domain protein HD-PTP. Therefore, we propose that the biogenesis of ApoExos begins when gasdermin-mediated endosomal pores increase cytosolic Ca2+, continues through the recruitment of annexin-sorcin/grancalcin-HD-PTP, and is completed when the ESCRT-III complex synthesizes intraluminal vesicles in the multivesicular bodies of dying cells. Finally, we found that Dfna5-bearing tumors released ApoExos to induce inflammatory responses in the in vivo 4T1 orthotropic model of breast cancer. The data presented in this study indicate that the switch from apoptosis to pyroptosis could drive the transfer of mass signals to nearby or distant living cells and tissues by way of extracellular vesicles, and that gasdermins play critical roles in that process.

Published
2021

9. Sugar-sweetened beverage and sugar intake during adolescence and risk of colorectal cancer precursors: a large prospective U.S. cohort study

Author

Joh, H.K., Lee, D.H., Hur, J., Nimptsch, K., Chang, Y., Joung, H., Zhang, X., Rezende, L.F.M., Lee, J.E., Ng, K., Chen, Y., Meyerhardt, J.A., Chan, A.T, Pischon, T., Song, M., Fuchs, C.S., Willett, W.C., Cao, Y., Ogino, S., Giovannucci, E., and Wu, K.

Subjects
Cardiovascular and Metabolic Diseases
Abstract

OBJECTIVE: To examine the associations of adolescent sugar-sweetened beverage (SSB) and sugar intake with risk of colorectal cancer (CRC) precursors. DESIGN: Prospective cohort study. SETTING: Nurses' Health Study II (1998-2015), United States. PARTICIPANTS: 33106 women who completed a validated high school food frequency questionnaire about adolescent diet in 1998 and underwent lower gastrointestinal endoscopy between 1999 and 2015. MAIN OUTCOME MEASURES: Incident CRC precursors confirmed by medical record review. RESULTS: During follow-up, 2909 conventional adenoma, 1082 high-risk adenoma (≥1 cm in size, villous, high-grade dysplasia, or number ≥2), and 2355 serrated lesions were identified. Independent of adult intake, adolescent SSB and sugar intake was positively associated with risk of total and high-risk adenoma. Comparing ≥2 servings/day v

Published
2020

10. Altered Cortical Gyrification Morphology in Nonsucidal Self-injury.

Author

Choi, S., Moon, H., and Hur, J.-W.

Subjects
BECK Anxiety Inventory, SUICIDE risk factors, MAGNETIC resonance imaging, TEMPORAL lobe, YOUNG adults
Abstract

Introduction: Nonsuicidal self-injury (NSSI) is defined as deliberate and direct damage to one's body tissues without any suicidal intent. NSSI is now recognized as a major risk factor for suicide and is prevalent among adolescents, with prevalence rates ranging from 7.5% to 46.5%, leading to increased interest in the pathophysiology of NSSI. This study aimed to examine cortical gyrification morphology, a neurobiological index of cortical folding and patterning, among unmedicated individuals with NSSI, which is prevalent in adolescents and young adults. Objectives: The main objective of this study is to compare cortical morphological abnormalities between individuals with NSSI and controls in terms of the local gyrification index (LGI), the ratio of the smooth cortical surface area at each vertex to the corresponding sulcal folds. In addition, we hypothesized that the LGI, a stable neurodevelopmental marker of cortical and subcortical circuit intergrity, would correlate with clinical measures in youth with NSSI. Methods: A total of 101 individuals with NSSI and 100 age-, gender-, and handedness-matched controls completed self-report questionnaires and structural magnetic resonance imaging (MRI) data were acquired on a 3T Siemens scanner. A surface-based analysis was conducted using the Computational Anatomy Toolbox (CAT12) in Statistical Parametric Mapping (SPM12). Partial correlation analysis was also performed using R software to investigate the association between the LGI values extracted from the region of interest (ROI) and clinical symptoms, including depression, anxiety, emotion dysregulation, and anhedonia in individuals with NSSI. Results: Individuals with NSSI showed significantly increased LGI in the right insula sulcus and left superior temporal sulcus (STS), along with decreased LGI in the right calcarine and left superior parietal sulcus (SPS), compared to controls (5000 permutation correction, threshold-free cluster enhancement with a threshold of p <.05). In addition, higher LGI in left STS was correlated with greater scores of the Beck Anxiety Inventory (r = 0.22 , p <.05) and of the Impulse Control Difficulties subscale of the Difficulties in Emotion Regulation Scale (r = 0.34 , p <.001). Conversely, reduced LGI of the right calcarine was associated with a higher score on the Anhedonia subscale of the Beck Depression Inventory (r = -0.23 , p <.05) within individuals with NSSI. Conclusions: This study identified hypergyria in the right insular and left STS and hypogyria in the right calcarine and left SPS in individuals with NSSI. The former pattern was associated with anxiety and impulse control difficulties, and the latter was with anhedonia. This study is the first to alter distinct neurodevelopmental patterns of local gyrification and their correlations with clinical manifestations in individuals with NSSI. Disclosure of Interest: None Declared [ABSTRACT FROM AUTHOR]

Published
2024
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11. Efficacy of Digital Interventions for Anxiety Disorders: A Systematic Review and Meta-Analysis.

Author

Ji, H.-G., Kang, S., Bae, H., Kim, G., and Hur, J.-W.

Subjects
ANXIETY disorders, RANDOMIZED controlled trials, DATA integrity, MENTAL illness, DATABASES, VIRTUAL reality
Abstract

Introduction: Anxiety disorders are one of the most common mental disorders, yet only less than 20% of people with anxiety disorders receive adequate treatment. Digital interventions for anxiety disorders can potentially increase access to evidence-based treatment. However, there is no comprehensive meta-analysis study that covers all modalities of digital interventions and all anxiety disorders. Objectives: A preliminary meta-analysis was conducted to examine the treatment efficacy of digital interventions [e.g., virtual reality (VR)-, mobile application-, internet-based interventions] for anxiety disorders and to identify potential moderators that may lead to better treatment outcomes. Methods: We searched Embase, PubMed, PsycINFO, Web of Science, and the Cochrane Library for randomized controlled trials examining the therapeutic efficacy of digital interventions for individuals with anxiety disorders from database inception to April 18, 2023. Search keywords were developed by combining the PICOS framework and MeSH terms. Data screening and extraction adhered to PRISMA guidelines. We used a random-effects model with effect sizes expressed as Hedge's g. The quality of the studies was assessed using the Revised Cochrane risk-of-bias tool for randomized trials (RoB 2). The study protocol was registered in PROSPERO on April 22, 2023 (CRD42023412139). Results: A systematic literature search identified 19 studies with randomized controlled trials (21 comparisons; 1936 participants) with high overall heterogeneity (Q = 104.49; P <.001; I 2 = 80.9%). Digital interventions reduced anxiety symptoms with medium to large effect sizes (g = 0.78; 95% CI: 0.55-1.02; P <.001), with interventions for specific phobia showing the largest effect size (n = 6; g = 1.22; 95% CI: 0.51-1.93; P <.001). VR-based interventions had a larger effect size (n = 6; g = 0.98; 95% CI: 0.39-1.57; P <.001) than mobile- or internet-based interventions, which had medium effect sizes. Meta-regression results exhibited that effect sizes of digital interventions were associated with the mean age of participants (β = 0.04; 95% CI: 0.02-0.06; P <.001). Conclusions: The results of this study provide evidence for the efficacy of digital interventions for anxiety disorders. However, this also suggests that the degrees of effectiveness in reducing anxiety symptoms can be moderated by the specific diagnosis, the modalities of digital technologies, and mean age, implying that the application of digital interventions for anxiety disorders should be accompanied by personalized guidance. Disclosure of Interest: None Declared [ABSTRACT FROM AUTHOR]

Published
2024
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12. High critical current density Mg[B.sub.2]/Fe multicore wires fabricated by an internal Mg diffusion process

Author

Hur, J., Togano, K., Matsumoto, A., Kumakura, H., Wada, H., and Kimura, K.

Subjects
Diffusion processes -- Analysis, Iron -- Electric properties, Iron -- Thermal properties, Magnesium compounds -- Electric properties, Magnesium compounds -- Thermal properties, Semiconductor doping -- Analysis, Silicon carbide -- Electric properties, Silicon carbide -- Thermal properties, Business, Electronics, Electronics and electrical industries
Published
2009

13. β-secretase (BACE1)-inhibiting stilbenoids from Smilax Rhizoma

Author

Jeon, S.-Y., Kwon, S.-H., Seong, Y.-H., Bae, K., Hur, J.-M., Lee, Y.-Y., Suh, D.-Y., and Song, K.-S.

Subjects
Sarsaparilla -- Research, Alzheimer's disease -- Care and treatment -- Research, Biological sciences, Health, Science and technology
Abstract

Abstract In the course of searching for BACE1 (β-secretase) inhibitors from natural products, the ethyl acetate soluble fraction of Smilax Rhizoma (the dried rhizomes of Smilax china L.) showed potent [...]

Published
2007

14. Added Value of Very High Resolution Climate Simulations Over South Korea Using WRF Modeling System

Author

Qiu, Liying EVNG, Im, Eun Soon, Hur, J., Shim, K.M., Qiu, Liying EVNG, Im, Eun Soon, Hur, J., and Shim, K.M.

Abstract

This study investigates the added value of very high resolution in long-term climate simulations over South Korea using the Weather Research and Forecasting (WRF) model. A one-way double-nested modeling system consisting of a mother domain (20-km resolution) and nested domain (5-km resolution) is customized for simulating the distinct climatological patterns in Korea, where the region-specific climate is largely influenced by the area’s complex geographical features. The ERA-Interim reanalysis data are used for the initial and boundary conditions, and the simulation spans the period from December 1, 1985 to December 31, 2005 (20-year analysis period with 1-month spin-up). Simulations from both the mother and the nested domain show reasonable performance in capturing the general characteristics of summer temperature and precipitation in terms of temporally and spatially averaged quantities. However, the added value from the nested domain with its higher resolution is apparently found in the reproduction of the intensity and frequency of extreme events and in the physical realism related to the partitioning of convective and large-scale precipitation. The nested domain not only better resolves the sharp gradients of temperature variation over short distances but also substantially reduces the systematic cold bias seen in temperature extremes produced by the mother domain. Furthermore, the nested domain is better able to simulate the upper tail of precipitation distributions and thus of extreme events. The higher resolution also improves the simulation of partitioning between convective and large-scale precipitation, leading to a plausible relationship between extreme precipitation and temperature and showing good agreement with in situ observation. Given the different behaviors of convective and large-scale precipitation in response to temperature changes, their realistic partitioning in the model has important potential for enhancing the reliability of precipitation

Published
2020

16. Organic carbon source-dependent properties of soluble microbial products in sequencing batch reactors and its effects on membrane fouling

Author

Ly, QV, Nghiem, LD, Cho, J, Maqbool, T, and Hur, J

Subjects
Spectrometry, Fluorescence, Bioreactors, Chromatography, Gel, Ultrafiltration, Membranes, Artificial, Environmental Sciences, Carbon
Abstract

© 2019 Elsevier Ltd This study investigated the influence of three different organic carbon sources including sodium acetate (SOD), glucose (GLU), and starch (STAR), on soluble microbial products (SMP), which presumably have dissimilar uptake rates and metabolic pathways, in sequencing batch reactors (SBR) and their subsequent effects on membrane fouling of ultrafiltration (UF). SMP were mainly characterized by fluorescence excitation emission matrix coupled with parallel factor analysis (EEM-PARAFAC) and size exclusion chromatography (SEC). SMP produced in SOD-fed SBR showed higher abundances of protein-like fluorescent component and large sized aliphatic biopolymer (BP) than GLU- or STAR-fed counterpart did, while the STAR-based operation resulted in more SMP enriched with humic-like fluorescence. The differences in SMP exerted marked effects on UF membrane fouling as indicated by the highest fouling potential with reversibility shown for the SMP from the SOD-fed reactor. Regardless of the carbon source, BP fraction and protein-like component exhibited the greatest extent of reversible fouling, suggesting that size exclusion plays a critical role. However, notable differences in the reversible fouling propensity of relatively smaller size fractions among the three SBRs signified the possible involvement of chemical interactions as a secondary fouling mechanism and its dependency on different carbon sources. Our results provide a new insight into the roles of carbon sources in the characteristics of SMP in biological treatment systems and their effects on the post-treatment using membrane filtration, which is ultimately beneficial to the optimization of biological treatment design and membrane filtration operation.

Published
2019

17. Interior potential of a toroidal shell from pole values

Author

Hur��, J. -M., Trova, A., Karas, V., Lesca, C., Bordeaux, Univ., France, CNRS-LAB, Bremen, University of, Technology, Center of Applied Space, Microgravity, Germany, Institute, Astronomical, Sciences, Academy of, Republic, Czech, ECLIPSE 2019, Laboratoire d'Astrophysique de Bordeaux [Pessac] (LAB), Université de Bordeaux (UB)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS)-Université de Bordeaux (UB)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS), Astronomical Institute of the Czech Academy of Sciences (ASU / CAS), Czech Academy of Sciences [Prague] (CAS), Institut de pharmacologie et de biologie structurale (IPBS), Centre National de la Recherche Scientifique (CNRS)-Université Toulouse III - Paul Sabatier (UT3), and Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées

Subjects
Physics, Mathematical analysis, Shell (structure), [SDU.ASTR.EP]Sciences of the Universe [physics]/Astrophysics [astro-ph]/Earth and Planetary Astrophysics [astro-ph.EP], FOS: Physical sciences, Astronomy and Astrophysics, Torus, Toroidal coordinates, Radius, Singular point of a curve, Curvature, 01 natural sciences, Gravitational potential, Astrophysics - Solar and Stellar Astrophysics, Space and Planetary Science, 0103 physical sciences, Elliptic integral, 010306 general physics, Astrophysics - Instrumentation and Methods for Astrophysics, 010303 astronomy & astrophysics, Instrumentation and Methods for Astrophysics (astro-ph.IM), Solar and Stellar Astrophysics (astro-ph.SR)
Abstract

We have investigated the toroidal analog of ellipsoidal shells of matter, which are of great significance in Astrophysics. The exact formula for the gravitational potential $\Psi(R,Z)$ of a shell with a circular section at the pole of toroidal coordinates is first established. It depends on the mass of the shell, its main radius and axis-ratio $e$ (i.e. core-to-main radius ratio), and involves the product of the complete elliptic integrals of the first and second kinds. Next, we show that successive partial derivatives $\partial^{n +m} \Psi/\partial_{R^n} \partial_{Z^m}$ are also accessible by analytical means at that singular point, thereby enabling the expansion of the interior potential as a bivariate series. Then, we have generated approximations at orders $0$, $1$, $2$ and $3$, corresponding to increasing accuracy. Numerical experiments confirm the great reliability of the approach, in particular for small-to-moderate axis ratios ($e^2 \lesssim 0.1$ typically). In contrast with the ellipsoidal case (Newton's theorem), the potential is not uniform inside the shell cavity as a consequence of the curvature. We explain how to construct the interior potential of toroidal shells with a thick edge (i.e. tubes), and how a core stratification can be accounted for. This is a new step towards the full description of the gravitating potential and forces of tori and rings. Applications also concern electrically-charged systems, and thus go beyond the context of gravitation., Comment: Accepted for publication in MNRAS

Published
2019

20. Dynamic analysis of ventricular repolarization duration from 24-hour Holter recordings

Author

Merri, Mario, Alberti, Michaela, and Moss, Art hur J.

Subjects
Electrocardiogram -- Analysis, Heart beat -- Research, Nervous system, Autonomic -- Research, Biological sciences, Business, Computers, Health care industry
Abstract

Evaluation of the influence of the autonomic nervous system on the ventricular repolarization duration was carried out using beat-to-beat analysis of the time intervals between the peaks of the R and T waves (RTm). After pre-processing of digitized Holter ECG's, auto and cross spectrum analyses were applied to heart rate and repolarization duration variability signals. Coherence analysis was used to assess the existence of common spectral contributions. The heart rate variability signal was used as reference of the sympatho-vagal balance at the sinus node. It was found that, in normal individuals, the autonomic nervous system directly influences the ventricular repolarization duration and that this influence is qualitatively very similar to the one that modulates the heart rate. Pathological alteration of these parallel autonomic activities to the heart (on the sinus node and on the ventricle) might cause uncoupling between depolarization and repolarization.

Published
1993

21. New monophyletic branches of the teloschistaceae (lichen-forming ascproved by three gene phylogenyomycota)

Author

Kondratyuk S. Y., Lokos L., Upreti D. K., Nayaka S., Mishra G. K., Ravera S., Jeong M. -H., Jang S. -H., Park J. S., Hur J. -S., Kondratyuk S.Y., Lokos L., Upreti D.K., Nayaka S., Mishra G.K., Ravera S., Jeong M.-H., Jang S.-H., Park J.S., and Hur J.-S.

Subjects
Phylogenetic analysi, Teloschistaceae, Three gene phylogeny, Phylogenetic tree
Abstract

Seventeen robust monophyletic branches newly discovered in the phylogenetic tree of the Teloschistaceae after separate nrITS, nrLSU and mtSSU, as well as combined phylogenetic analysis are proposed to consider as the following separate genera: Dijigiella S. Y. Kondr. et L. Lo′kös gen. nov. for the D. kaernefeltiana group, Elixjohnia S. Y. Kondr. et J.-S. Hur gen. nov. for the Sirenophila jackelixii group, Fominiella S. Y. Kondr., D. Upreti et J.-S. Hur gen. nov. for the F. tenerifensis group; Gintarasiella S. Y. Kondr. et J.-S. Hur gen. nov. for Caloplaca aggregata, Hanstrassia S. Y. Kondr. gen. nov. for the Elenkiniana lenae group, Harusavskia S. Y. Kondr. gen. nov. for H. elenkinianoides sp. n., Huriella S. Y. Kondr. et D. Upreti gen. nov. for H. loekoesiana sp. n., Ikaeria S. Y. Kondr., D. Upreti et J.-S. Hur gen. nov. for Caloplaca aurantiellina, Klauderuiella S. Y. Kondr. et J.-S. Hur gen. nov. for the Variospora thallincola group, Laundonia S. Y. Kondr., L. Lo′kös et J.-S. Hur gen. nov. for the Gyalolechia flavovirescens group, Lazarenkoiopsis S. Y. Kondr., L. Lo′kös et J.-S. Hur gen. nov. for Caloplaca ussuriensis, Nevilleiella S. Y. Kondr. et J.-S. Hur gen. nov. for the Caloplaca marchantii group, Opeltia S. Y. Kondr. et L. Lo′kös gen. nov. for the Caloplaca neobaltistanica group, Oxneriopsis S. Y. Kondr., D. Upreti et J.-S. Hur gen. nov. for the Caloplaca oxneri group, Teuvoahtiana S. Y. Kondr. et J.-S. Hur gen. nov. for the Caloplaca rugulosa group, Tomnashia S. Y. Kondr. et J.-S. Hur gen. nov. for the Polycauliona rosei group, and Xanthaptychia S. Y. Kondr. et S. Ravera gen. nov. for the Seirophora orientalis group. Hitherto missing molecular data on three gene sequences of the type species of the genera Seirophora and Sirenophila are completed within this study. Six new to science species (Dijigiella kaernefeltiana S. Y. Kondr. sp. n., D. subaggregata S. Y. Kondr. et Kärnefelt sp. n., Fominiella tenerifensis S. Y. Kondr., Kärnefelt, A. Thell et T. Feuerer sp. n., Hanstrassia jaeseounhurii S. Y. Kondr., Ch.-H. Park et L. Lo′kös sp. n., Harusavskia elenkinianoides S. Y. Kondr., X. Y. Wang, S.-O. Oh et J.-S. Hur sp. n., Huriella loekoesiana S. Y. Kondr. et D. Upreti sp. n.) are described, compared with closely related taxa. A total of 34 new combinations for genera mentioned above are proposed.

Published
2017

22. Evaluation of an App-based brief Cognitive Behavioral Therapy for individuals with Nonsuicidal Self-injury.

Author

Kang, S., Zoh, S. M., and Hur, J.-W.

Subjects
COGNITIVE therapy, YOUNG adults, EMOTION regulation, MENTAL depression, PUBLIC health
Abstract

Introduction: Nonsuicidal self-injury (NSSI), the deliberate and direct destruction of one's own body tissue without suicidal intent, has represented a significant public health concern among adolescents and young adults worldwide, yet they have limited access to evidence-based interventions. App-based digital therapy, with its advantages of high cost-effectiveness, accessibility, and user receptivity, could be an effective intervention for NSSI. We expected that the use of an app-based brief cognitive-behavioral therapy (CBT) would improve depressive symptoms and emotion dysregulation, the most prevalent symptoms among individuals with NSSI. Objectives: This study aimed to evaluate the efficacy of a 3-week app-based brief CBT program focusing on cognitive distortion correction for individuals with NSSI. Methods: A total of 34 participants who engaged in NSSI were included in the final analysis, with 18 individuals assigned to the 'app group' and 16 to the 'waitlist group.' The brief CBT program consisted of three quizzes designed to prompt the users to identify cognitive distortions embedded in a series of short scenarios, develop more realistic perspectives, and imagine advising to significant others. The app group was instructed to complete three quizzes per day for three weeks, while the waitlist group received no intervention. Results: Baseline and follow-up assessments of depression and emotion regulation were conducted. After the 3-week program, the app group showed a significant reduction in depressive symptoms (F  = 8.30,  P  =.007) compared to the waitlist group. There was no group difference regarding emotion regulation. Conclusions: Depression is a prominent symptom in individuals with NSSI. Our findings suggest that an app-based brief CBT intervention targeting cognitive distortions can effectively alleviate depression in individuals with NSSI. The results also highlight the need for digital interventions that are tailored and designed to improve emotion regulation in this population. Disclosure of Interest: None Declared [ABSTRACT FROM AUTHOR]

Published
2024
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24. Effects of COD/N ratio on soluble microbial products in effluent from sequencing batch reactors and subsequent membrane fouling

Author

Ly, QV, Nghiem, LD, Sibag, M, Maqbool, T, Hur, J, Ly, QV, Nghiem, LD, Sibag, M, Maqbool, T, and Hur, J

Abstract

© 2018 Elsevier Ltd The relative ratios of chemical oxygen demand (COD) to nitrogen (N) in wastewater are known to have profound effects on the characteristics of soluble microbial products (SMP) from activated sludge. In this study, the changes in the SMP characteristics upon different COD/N ratios and the subsequent effects on ultrafiltration (UF) membrane fouling potentials were examined in sequencing batch reactors (SBR) using excitation emission matrix-parallel factor analysis (EEM-PARAFAC) and size exclusion chromatography (SEC). Three unique fluorescent components were identified from the SMP samples in the bioreactors operated at the COD/N ratios of 100/10 (N rich), 100/5 (N medium), and 100/2 (N deficient). The tryptophan-like component (C1) was the most depleted at the N medium condition. Fulvic-like (C2) and humic-like (C3) components were more abundant with N rich wastewater. Greater abundances of large size biopolymer (BP) and low molecular weight neutrals (LMWN) were found under the N deficient and N rich conditions, respectively. SMPs from various COD/N exhibited a greater degree on membrane fouling following the order of 100/2 > 100/10 > 100/5. C1 and C2 had close associations with reversible and irreversible fouling, respectively, while the reversible fouling potential of C3 depended on the COD/N ratios. No significant impact of COD/N ratio was observed on the relative contributions of SMP size fractions to either reversible or irreversible fouling potential. However, the COD/N ratios likely altered the BP foulants' composition with greater contribution of proteinaceous substances to reversible fouling under the N deficient condition than at other N richer conditions. The opposite trend was observed for irreversible fouling. Our results provided further insight into changes in different SMP constitutes and their membrane fouling in response to microbial activities under different COD/N ratios.

Published
2018

25. Insights into the roles of recently developed coagulants as pretreatment to remove effluent organic matter for membrane fouling mitigation

Author

Ly, QV, Nghiem, LD, Cho, J, Hur, J, Ly, QV, Nghiem, LD, Cho, J, and Hur, J

Abstract

© 2018 Elsevier B.V. Membrane fouling by dissolved organic matter (EfOM) in secondary treated effluent is a problematic and inevitable issue during wastewater reclamation using low pressure membrane filtration. This study evaluates the performance of coagulation/flocculation (C/F) using two recently developed coagulants (namely TiCl4 and ZrCl4) in comparison to conventional alum (i.e. Al2(SO4)3) as pretreatment to remove EfOM for subsequent ultrafiltration (UF) membrane fouling mitigation. At the optimal dosage, TiCl4-based C/F pretreatment showed the greatest performance in membrane fouling mitigation, followed by ZrCl4 and then alum. The underlying mechanisms were well explained by classical fouling models and the extended Derjaguin-Landau-Verwey-Overbeek (xDLVO) theory, highlighting a dominant role of standard blocking in the fouling potential of the C/F treated EfOM. The interfacial free energy of cohesion and adhesion showed that C/F pretreatment using TiCl4 and ZrCl4 as coagulant can lower the binding affinity between EfOM molecules and between EfOM molecules and membrane surface, ultimately reduce membrane fouling. The results of size exclusion chromatography (SEC) and fluorescence excitation emission matrix- parallel factor analysis (EEM-PARAFAC) also supported the classical fouling mechanisms, providing additional insights into the potential roles of chemical interactions in the preferential removal of certain organic substances by C/F pretreatment and the chemical composition of subsequent membrane foulants. Protein-like components were highly associated with reversible fouling after the C/F, while the reversibility of humic-like substances was enhanced upon C/F pretreatment. After C/F pretreatment, small sized EfOM molecules became the dominant fraction responsible for UF membrane fouling.

Published
2018

26. Abnormal RNA stability in amyotrophic lateral sclerosis

Author

Tank, E. M., primary, Figueroa-Romero, C., additional, Hinder, L. M., additional, Bedi, K., additional, Archbold, H. C., additional, Li, X., additional, Weskamp, K., additional, Safren, N., additional, Paez-Colasante, X., additional, Pacut, C., additional, Thumma, S., additional, Paulsen, M. T., additional, Guo, K., additional, Hur, J., additional, Ljungman, M., additional, Feldman, E. L., additional, and Barmada, S. J., additional

Published
2018
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31. Thinning of the RPE and choroid associated with T lymphocyte recruitment in aged and light-challenged mice

Author

Camelo, S., Calippe, B., Lavalette, S., Dominguez, E., Hur, J., Devevre, E., Guillonneau, X., William Raoul, Sennlaub, F., Unité de Recherche Clinique, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Lariboisière-Fernand-Widal [APHP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Institut de la Vision, Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Centre de Recherche des Cordeliers (CRC (UMR_S 872)), Université Pierre et Marie Curie - Paris 6 (UPMC)-Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Génétique, immunothérapie, chimie et cancer (GICC), UMR 7292 CNRS [2012-2017] (GICC UMR 7292 CNRS), Université de Tours (UT)-Centre National de la Recherche Scientifique (CNRS), ERC-2007 St.G. 210345, Raoul, William, Université de Tours-Centre National de la Recherche Scientifique (CNRS), Assistance publique - Hôpitaux de Paris (AP-HP)-Hôpital Lariboisière, Centre National de la Recherche Scientifique ( CNRS ) -Institut National de la Santé et de la Recherche Médicale ( INSERM ) -Université Pierre et Marie Curie - Paris 6 ( UPMC ), Centre de Recherche des Cordeliers ( CRC (UMR_S 872) ), Université Pierre et Marie Curie - Paris 6 ( UPMC ) -Université Paris Descartes - Paris 5 ( UPD5 ) -Institut National de la Santé et de la Recherche Médicale ( INSERM ) -Centre National de la Recherche Scientifique ( CNRS ), Génétique, Immunothérapie, Chimie et Cancer ( GICC ), Université de Tours-Centre National de la Recherche Scientifique ( CNRS ), and Université Paris Descartes - Paris 5 (UPD5)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)

Subjects
cis-trans-Isomerases, Aging, Light, genetic structures, Retinal Pigment Epithelium, Chemokine CXCL9, Mice, Cell Movement, Animals, Humans, RNA, Messenger, [SDV.NEU] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC], [SDV.MHEP.OS]Life Sciences [q-bio]/Human health and pathology/Sensory Organs, Choroid, Photochemical Processes, eye diseases, Chemokine CXCL10, Mice, Inbred C57BL, Oxidative Stress, Gene Expression Regulation, [SDV.MHEP.OS] Life Sciences [q-bio]/Human health and pathology/Sensory Organs, [ SDV.NEU ] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC], [ SDV.MHEP.OS ] Life Sciences [q-bio]/Human health and pathology/Sensory Organs, [SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC], sense organs, T-Lymphocytes, Cytotoxic, Research Article
Abstract

International audience; The choroidal vasculature is essential when it comes to bringing oxygen and nutrients to the functioning retina and evacuating debris resulting from the normal visual cycle. Choroidal thinning is a common feature in many human eye diseases, including high myopia [1,2] and retinitis pigmentosa [3,4], and has been reproducibly observed with age [5-7]. However, the association between choroidal thinning and age-related macular degeneration (AMD) remains controversial. Some authors have reported the loss of choriocapillaries in eyes with exudative AMD [8], and choroidal thinning has been detected in some studies [9-11]. Choroidal thinning has also been associated with geographic atrophy (GA), the dry form of late AMD [12-15]. A morphometric analysis by Ramrattan et al. more than two decades ago showed a decrease in choriocapillary density and diameter with age and in GA, but choroidal thinning was only significant with age [6]. Moreover, it has been reported that the choriocapillaries and choroid are thinner in areas where the RPE has degenerated [8]. However, all studies agree that aging is associated with significant choroidal thinning [16-18]. The exact mechanisms behind choroidal thinning with age or disease are not clear. The RPE is a monolayer of pigmented cells situated between photoreceptors and Bruch's membrane; its plays an essential role in the visual cycle. RPE65, which is also called 11-cis retinol isomerase and is strongly expressed in the RPE, participates in the production of 11-cis retinal [19], which is essential for photoreceptor function [20]. Mutations in the RPE65 gene cause progressive photoreceptor degeneration [21,22] and adult RPE65 −/−

Published
2015

33. First data on molecular phylogeny of the genus Protoparmeliopsis M. Choisy (Lecanoraceae, Ascomycota)

Author

Kondratyuk S., Kim J., Kondratiuk A., Jeong M.-H., Jang S.-H., Pirogov M., and Hur J.-S.

Subjects
nuclear, sequences, Lecanora, mitochondrial DNA, Protoparmeliopsis, Rhizoplaca
Abstract

Results on molecular phylogeny of lichen-forming fungi of the genus Protoparmeliopsis based on nrDNA ITS1/ITS2 and 28S LSU and mtDNA 12S SSU as well as on combined data set are provided. The position of this genus in the phylogenetic tree of the family Lecanoraceae is discussed. The genus Protoparmeliopsis found to be polyphyletic similarly to the genera Rhizoplaca, Lecanora and Protoparmelia.

Published
2014
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36. Phylogeny and taxonomy of the Teloschistaceae (Ascomycota): Importance of monophyletic groups

Author

Kondratyuk S., Jeong M.-H., Kärnefelt I., Elix J., Hur J.-S., and Thell A.

Subjects
ITS1/ITS2, Teloschistaceae, DNA, lichen-forming fungi, Letrouitiaceae, molecular phylogeny
Abstract

The molecular phylogeny of the Parmeliaceae, Physciaceae, Caliciaceae and many other families of lichen-forming fungi is now based on polyphasic approach using up to six or seven different genes of nuclear and mitochondrial DNA. As a consequence the taxonomy of the Parmeliaceae and other families can now be based on segregation of robust monophyletic groups of species. The majority of phylogenetic analyses of small species groups of the Teloschistaceae (especially of Caloplaca) are based on ITS1/ITS2 sequences of nuclear DNA as the main molecular tool. There are fewer reports of polyphasic molecular data having been used in such phylogenetic analyses (Gaya 2003, 2008; Fedorenko 2009, 2012). Such investigations have indicated that the currently accepted genera Caloplaca, Fulgensia, Xanthoria and Teloschistes are polyphyletic and the delineation of Caloplaca and Xanthoria and of Caloplaca and Fulgensia is problematic. The existence of well defined monophyletic groups within species groups like those of Caloplaca cerina, C.saxicola, C. regalis, C. ferruginea, C. variabilis and Fulgensia fulgens (some of which are type species of different genera proposed in ‘premolecular time’) are found to be distributed among other monophyletic branches of the xanthorioid lichens following analysis of nuclear molecular data. As a consequence generic names proposed for the above species groups (i.e. Blastenia, Pyrenodesmia, Polycauliona etc.) can be used together with Caloplaca s.str., Teloschistes, Seirophora and Fulgensia. However, it should be emphasized that following molecular analysis such groups/genera as Blastenia, Pyrenodesmia and the Caloplaca saxicola- group include far fewer species than was proposed from morphological segregation in the ‘premolecular’ period. Alternatively, molecular data confirms that the morphologically defined groups (i.e. Blastenia, Pyrenodesmia, Polycauliona etc.) are just as polyphyletic as the genera Teloschistes, Seirophora and Fulgensia. Caloplaca subgenus Gasparrinia is similarly polyphyletic. Furthermore, there have been recent proposals to retain the xanthorioid genera Jackelixia, Ovealmbornia, Xanthokarooa within Xanthoria. However, this is in complete disagreement with the presently accepted molecular phylogenetic tree of the Teloschistaceae. Molecular data indicates that Jackelixia, Ovealmbornia and Xanthokarooa could be considered to belong to Xanthodactylon s.l., but certainly not Xanthoria s.l. Further, present molecular data does not support the families Letrouitiaceae and Teloschistaceae. In future we will probably have three families, i.e. Teloschistaceae s. emend., Caloplacaceae s. emend. and Xanthoriaceae s. emend., instead of the two mentioned above. Special attention to monophyletic groups in the current Teloschistaceae as well as wider usage of a polyphasic molecular approach will also help to clarify the position and circumscription of generic groups within these families.

Published
2012
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37. Identification of Cladosporium sphaerospermum species complex after morphology and molecular phylogeny

Author

Kondratyuk T., Jeong M.-H., Hur J.-S., and Kondratyuk S.

Subjects
ITS1/UTS2, phylogenetic analysis, morphology, food and beverages, Ukraine, Cladosporium
Abstract

Cladosporium isolates, which are morphologically similar to C. sphaerospermum were phylogenetically analyzed on the basis of DNA sequences and of the ribosomal RNA (the internal transcribed spacer regions ITS1 and ITS 2, the 5.8 S rDNA (ITS)). Six analyzed isolates have found to represent three species of C. sphaerospermum complex. Cladosporium halotolerans and C. psyhrotolerans are for the first time recorded for Ukraine.

Published
2012
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41. An Automated Sensor Fusion Approach for the RUL Prediction of Electromagnetic Pumps

Author

Ugochukwu Ejike Akpudo and Hur Jang-Wook

Subjects
Sensor fusion, remaining useful life prediction, electromagnetic pumps, MOGA-LSTM, wavelet decomposition, Electrical engineering. Electronics. Nuclear engineering, TK1-9971
Abstract

The remaining useful life (RUL) prediction of industrial cyber-physical system components demands the use of reliable prognostics parameters and frameworks. Against the traditional use of a single measure of degradation, data from multiple sensors provide abundant characteristic information for modeling, assessing, and extracting useful parameters via appropriate signal processing and sensor fusion methods. This study introduces a multi-sensor prognostics approach which merges highly prognosible statistical features from vibrational and pressure sensor measurements after a multi-level wavelet decomposition of the signals. The prognostic algorithm presented in this work for solenoid pump RUL prediction is a multi-objective genetic algorithm-optimized long short-term memory (MOGA-LSTM) which accepts the fused sensor features as input and returns the RUL of the pump as output. The framework was tested on a run-to-failure experiment on a VSC63A5 Solenoid pump following a significant pump malfunction caused by a clogged suction filter after the test. Using standard prognostic performance evaluation metrics, the performance of the prognostics framework was compared with other reliable state-of-the-art methods with a remarkable comparative advantage in addition to better automation potentials for real-time condition monitoring and RUL prediction.

Published
2021
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44. Intraperitoneal injection of the pancreatic peptide amylin potently reduces behavioral impairment and brain amyloid pathology in murine models of Alzheimer’s disease

Author

Zhu, H, primary, Wang, X, additional, Wallack, M, additional, Li, H, additional, Carreras, I, additional, Dedeoglu, A, additional, Hur, J-Y, additional, Zheng, H, additional, Fine, R, additional, Mwamburi, M, additional, Sun, X, additional, Kowall, N, additional, Stern, R A, additional, and Qiu, W Q, additional

Published
2014
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45. Multi-level LINC transmitter with non-isolated power combiner

Author

Hur, J., Kim, H., Lee, O., Woo, S., Kim, K., Kim, W., Lee, C.H., Lim, K., Laskar, Joy, Hur, J., Kim, H., Lee, O., Woo, S., Kim, K., Kim, W., Lee, C.H., Lim, K., and Laskar, Joy

Abstract

By using a non-isolated power combiner, the overall power efficiency can be improved by reducing the wasted power at the combined out-phased signal. To further improve the efficiency of the low-power mode, a multi-power mode out-phasing power amplifier (PA) is proposed with load modulation by switches. Compared with the conventional linear amplification using nonlinear component (LINC) transmitter, the proposed multi-level LINC improves the power-added-efficiency more than 40% for a 7 dB peak-to-average power ratio orthogonal frequency division multiplexing signal. To the authors' knowledge, the proposed LINC PA is the first multi-level LINC PA without multiple power supplies.

Published
2013

47. Remaining Useful Life Estimation of BLDC Motor Considering Voltage Degradation and Attention-Based Neural Network

Author

Tanvir Alam Shifat and Hur Jang-Wook

Subjects
Attention mechanism, BLDC motor, remaining useful life, LSTM, stator fault, Electrical engineering. Electronics. Nuclear engineering, TK1-9971
Abstract

Brushless DC motor, also referred to as BLDC motor, has been a widely used electric machine due to its excellent performance over conventional DC motors. Due to complex operating conditions and overloading, several irregularities can take place in a motor. Stator related faults are among the most commonly occurring faults in BLDC motor. With an initial raise in local heating, a fault in the stator can largely reduce motor efficiency and account for the entire system breakdown. In this study, we present a deep learning-based approach to estimate the remaining useful life (RUL) of BLDC motor affected by different stator related faults. To analyze the motor health degradation, we have investigated two types of stator faults namely inter-turn fault (ITF) and winding short-circuit fault (WSC). A generator was coupled with the motor and using an average value rectifier (AVR), generator's output voltage was monitored for the entire lifecycle. A proven neural network for effective sequence modeling, recurrent neural network (RNN) is selected to train the voltage degradation data. For a better estimation of nonlinear trends, long-short term memory (LSTM) with attention mechanism is chosen to make predictions of the motor RUL for both types of faults. The main concern that encourages authors of this paper is the proposed method can be used for the real-time condition monitoring and health state estimation of BLDC motors. Also, the proposed AVR-LSTM method is not affected by environmental influences, making it suitable for diverse operating conditions.

Published
2020
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48. A Multi-Domain Diagnostics Approach for Solenoid Pumps Based on Discriminative Features

Author

Ugochukwu Ejike Akpudo and Hur Jang-Wook

Subjects
Binary particle swarm optimization, comprehensive feature extraction, continuous wavelet transform, Mel frequency cepstral coefficients, solenoid pumps, support vector machine, Electrical engineering. Electronics. Nuclear engineering, TK1-9971
Abstract

Accurate condition monitoring of industrial cyber-physical systems/components demands the use of reliable fault detection and isolation (FD&I) methodologies. Meta-heuristic algorithms for feature selection have good exploration capability for optimal discriminative feature selection for fault isolation/classification of which the Binary Particle swarm optimization (BPSO) is superior to its counterparts. This study presents a robust approach for vibration-based failure diagnostics of electromagnetic/solenoid pumps which employ a multi-domain feature extraction procedure (statistical time-domain and frequency-domain features, Mel frequency cepstral coefficients, and continuous wavelet coefficients) for capturing linear and nonlinear properties from the signals. Compared with other filter and wrapper methods for supervised feature selection, a hybrid filter-wrapper (Pearson's correlation-BPSO (ρ-BPSO)) feature selection procedure is proposed for global search of optimal discriminative (uncorrelated) features for fault diagnosis with an RBF-kernel support vector machine (SVM*). Subsequently, a practical case study involving five VSC63A5 solenoid pumps at various operating/fault conditions is presented for validating the performance of the proposed approach. Results show the superior performance of the proposed hybrid filter-wrapper approach against filter-based and wrapper-based techniques for discriminative feature selection. Also, the proposed ρ-BPSO-SVM* diagnostics model performance was compared with other standard fault isolation/classification methods.

Published
2020
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