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1. Learning imaging in axial spondyloarthritis: more than just a matter of experience

Author

Radny, Felix, primary, Ziegeler, Katharina, additional, Eshed, Iris, additional, Greese, Juliane, additional, Deppe, Dominik, additional, Stelbrink, Carsten, additional, Biesen, Robert, additional, Haibel, Hildrun, additional, Rios Rodriguez, Valeria, additional, Rademacher, Judith, additional, Protopopov, Mikhail, additional, Proft, Fabian, additional, Hermann, Kay Geert A, additional, Poddubnyy, Denis, additional, Diekhoff, Torsten, additional, and Ulas, Sevtap Tugce, additional

Published
2024
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8. Deep Learning Detects Changes Indicative of Axial Spondyloarthritis at MRI of Sacroiliac Joints

Author

Bressem, Keno K., primary, Adams, Lisa C., additional, Proft, Fabian, additional, Hermann, Kay Geert A., additional, Diekhoff, Torsten, additional, Spiller, Laura, additional, Niehues, Stefan M., additional, Makowski, Marcus R., additional, Hamm, Bernd, additional, Protopopov, Mikhail, additional, Rios Rodriguez, Valeria, additional, Haibel, Hildurn, additional, Rademacher, Judith, additional, Torgutalp, Murat, additional, Lambert, Robert G., additional, Baraliakos, Xenofon, additional, Maksymowych, Walter P., additional, Vahldiek, Janis L., additional, and Poddubny, Denis, additional

Published
2023
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10. Current Role of Conventional Radiography of Sacroiliac Joints in Adults and Juveniles with Suspected Axial Spondyloarthritis: Opinion from the ESSR Arthritis and Pediatric Subcommittees

Author

Sudoł-Szopińska, Iwona, Herregods, Nele, Zejden, Anna, Jans, Lennart, Giraudo, Chiara, Boesen, Mikael, Becce, Fabio, Bazzocchi, Alberto, Simoni, Paolo, Aparisi, Pilar, Jaremko, Jacob J.L., Maas, Mario, Teh, James, Hermann, Kay Geert, Menegotto, Flavia, Isaac, Amanda, Reijnierse, Monique, Shah, Amit, Rennie, Winston W.J., Jurik, Anne Grethe, Sudoł-Szopińska, Iwona, Herregods, Nele, Zejden, Anna, Jans, Lennart, Giraudo, Chiara, Boesen, Mikael, Becce, Fabio, Bazzocchi, Alberto, Simoni, Paolo, Aparisi, Pilar, Jaremko, Jacob J.L., Maas, Mario, Teh, James, Hermann, Kay Geert, Menegotto, Flavia, Isaac, Amanda, Reijnierse, Monique, Shah, Amit, Rennie, Winston W.J., and Jurik, Anne Grethe

Abstract

This opinion article by the European Society of Musculoskeletal Radiology Arthritis and Pediatric Subcommittees discusses the current use of conventional radiography (CR) of the sacroiliac joints in adults and juveniles with suspected axial spondyloarthritis (axSpA). The strengths and limitations of CR compared with magnetic resonance imaging (MRI) and computed tomography (CT) are presented. Based on the current literature and expert opinions, the subcommittees recognize the superior sensitivity of MRI to detect early sacroiliitis. In adults, supplementary pelvic radiography, low-dose CT, or synthetic CT may be needed to evaluate differential diagnoses. CR remains the method of choice to detect structural changes in patients with suspected late-stage axSpA or established disease and in patients with suspected concomitant hip or pubic symphysis involvement. In children, MRI is the imaging modality of choice because it can detect active as well as structural changes and is radiation free., SCOPUS: ar.j, info:eu-repo/semantics/published

Published
2023

11. Current Role of Conventional Radiography of Sacroiliac Joints in Adults and Juveniles with Suspected Axial Spondyloarthritis:Opinion from the ESSR Arthritis and Pediatric Subcommittees

Author

Sudoł-Szopińska, Iwona, Herregods, Nele, Zejden, Anna, Jans, Lennart, Giraudo, Chiara, Boesen, Mikael, Becce, Fabio, Bazzocchi, Alberto, Simoni, Paolo, Aparisi, Pilar, Jaremko, Jacob, Maas, Mario, Teh, James, Hermann, Kay Geert, Menegotto, Flavia, Isaac, Amanda, Reijnierse, Monique, Shah, Amit, Rennie, Winston, Jurik, Anne Grethe, Sudoł-Szopińska, Iwona, Herregods, Nele, Zejden, Anna, Jans, Lennart, Giraudo, Chiara, Boesen, Mikael, Becce, Fabio, Bazzocchi, Alberto, Simoni, Paolo, Aparisi, Pilar, Jaremko, Jacob, Maas, Mario, Teh, James, Hermann, Kay Geert, Menegotto, Flavia, Isaac, Amanda, Reijnierse, Monique, Shah, Amit, Rennie, Winston, and Jurik, Anne Grethe

Abstract

This opinion article by the European Society of Musculoskeletal Radiology Arthritis and Pediatric Subcommittees discusses the current use of conventional radiography (CR) of the sacroiliac joints in adults and juveniles with suspected axial spondyloarthritis (axSpA). The strengths and limitations of CR compared with magnetic resonance imaging (MRI) and computed tomography (CT) are presented.Based on the current literature and expert opinions, the subcommittees recognize the superior sensitivity of MRI to detect early sacroiliitis. In adults, supplementary pelvic radiography, low-dose CT, or synthetic CT may be needed to evaluate differential diagnoses. CR remains the method of choice to detect structural changes in patients with suspected late-stage axSpA or established disease and in patients with suspected concomitant hip or pubic symphysis involvement. In children, MRI is the imaging modality of choice because it can detect active as well as structural changes and is radiation free.

Published
2023

13. Deep Learning Detects Changes Indicative of Axial Spondyloarthritis at MRI of Sacroiliac Joints

Author

Bressem, Keno K., primary, Adams, Lisa C., additional, Proft, Fabian, additional, Hermann, Kay Geert A., additional, Diekhoff, Torsten, additional, Spiller, Laura, additional, Niehues, Stefan M., additional, Makowski, Marcus R., additional, Hamm, Bernd, additional, Protopopov, Mikhail, additional, Rios Rodriguez, Valeria, additional, Haibel, Hildurn, additional, Rademacher, Judith, additional, Torgutalp, Murat, additional, Lambert, Robert G., additional, Baraliakos, Xenofon, additional, Maksymowych, Walter P., additional, Vahldiek, Janis L., additional, and Poddubnyy, Denis, additional

Published
2022
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15. Anatomical variation of the sacroiliac joint carries an increased risk for erosion and bone marrow oedema in axial spondyloarthritis.

Author

Ziegeler, Katharina, Ulas, Sevtap Tugce, Poddubnyy, Denis, Proft, Fabian, Rodriguez, Valeria Rios, Rademacher, Judith, Hermann, Kay Geert A, and Diekhoff, Torsten

Subjects
SACROILIAC joint radiography, SACROILIAC joint, CONFIDENCE intervals, ANKYLOSIS, MAGNETIC resonance imaging, SPONDYLOARTHROPATHIES, RISK assessment, DESCRIPTIVE statistics, RESEARCH funding, BONE marrow diseases, LOGISTIC regression analysis, ODDS ratio, EDEMA, LONGITUDINAL method, DISEASE risk factors
Abstract

Objectives To assess the impact of joint shape variations on inflammatory lesions on SI joint MRIs in patients with axial spondyloarthritis (axSpA). Methods A total of 1194 patients from four different prospective cohorts were evaluated, with 684 (57.3%) having sufficient imaging data for inclusion (379 axSpA, 305 controls). All images were evaluated for joint form, erosion, sclerosis, fat metaplasia and bone marrow oedema (BMO) by two independent readers. Logistic regression analyses were used to assess the association of joint form and lesions on imaging for axSpA patients and controls. Results Atypical joint forms were common in both axSpA (43.5% [154/354]) and control patients (44.2% [134/303]); both intra-articular variants and a crescent joint shape were significantly more common in axSpA patients (18.4% vs 11.6% and 11.0% vs 5.3.%, respectively; P  < 0.001). The axSpA patients with intra-articular joint form variants had 2-fold higher odds of exhibiting erosions [odds ratio (OR) 2.09 (95% CI 1.18, 3.69)] and BMO [OR 1.79 (95% CI 1.13, 2.82)]; this association was not observed in controls. Accessory joints increased the odds for sclerosis in axSpA patients [OR 2.54 (95% CI 1.10, 5.84)] and for sclerosis [OR 17.91 (95% CI 6.92, 46.37)] and BMO [OR 2.05 (95% CI 1.03, 4.07)] in controls. Conclusions Joint form variations are associated with the presence of inflammatory lesions on SI joint MRIs of axSpA patients. This should be taken into consideration in future research on the interplay of mechanical strain and inflammation in axSpA. [ABSTRACT FROM AUTHOR]

Published
2023
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24. Detection of radiographic sacroiliitis with an artificial neural network in patients with suspicion of axial spondyloarthritis

Author

Poddubnyy, Denis, primary, Proft, Fabian, additional, Hermann, Kay-Geert A, additional, Spiller, Laura, additional, Niehues, Stefan M, additional, Adams, Lisa C, additional, Protopopov, Mikhail, additional, Rios Rodriguez, Valeria, additional, Muche, Burkhard, additional, Rademacher, Judith, additional, Torgutalp, Murat, additional, Bressem, Keno K, additional, and Vahldiek, Janis L, additional

Published
2021
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25. sj-docx-1-tab-10.1177_1759720X211057975 ��� Supplemental material for Axial Involvement in Psoriatic Arthritis cohort (AXIS): the protocol of a joint project of the Assessment of SpondyloArthritis international Society (ASAS) and the Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA)

Author

Poddubnyy, Denis, Baraliakos, Xenofon, Van den Bosch, Filip, Braun, J��rgen, Coates, Laura C., Chandran, Vinod, Diekhoff, Torsten, van Gaalen, Floris A., Gensler, Lianne S., Goel, Niti, Gottlieb, Alice B., van der Heijde, D��sir��e, Helliwell, Philip S., Hermann, Kay Geert A., Jadon, Deepak, Lambert, Robert G., Maksymowych, Walter P., Mease, Philip, Nash, Peter, Proft, Fabian, Protopopov, Mikhail, Sieper, Joachim, Torgutalp, Murat, and Gladman, Dafna D.

Subjects
FOS: Clinical medicine, 110604 Sports Medicine, FOS: Health sciences, 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified, 110314 Orthopaedics
Abstract

Supplemental material, sj-docx-1-tab-10.1177_1759720X211057975 for Axial Involvement in Psoriatic Arthritis cohort (AXIS): the protocol of a joint project of the Assessment of SpondyloArthritis international Society (ASAS) and the Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA) by Denis Poddubnyy, Xenofon Baraliakos, Filip Van den Bosch, J��rgen Braun, Laura C. Coates, Vinod Chandran, Torsten Diekhoff, Floris A. van Gaalen, Lianne S. Gensler, Niti Goel, Alice B. Gottlieb, D��sir��e van der Heijde, Philip S. Helliwell, Kay Geert A. Hermann, Deepak Jadon, Robert G. Lambert, Walter P. Maksymowych, Philip Mease, Peter Nash, Fabian Proft, Mikhail Protopopov, Joachim Sieper, Murat Torgutalp and Dafna D. Gladman in Therapeutic Advances in Musculoskeletal Disease

Published
2021
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26. sj-docx-2-tab-10.1177_1759720X211057975 ��� Supplemental material for Axial Involvement in Psoriatic Arthritis cohort (AXIS): the protocol of a joint project of the Assessment of SpondyloArthritis international Society (ASAS) and the Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA)

Author

Poddubnyy, Denis, Baraliakos, Xenofon, Van den Bosch, Filip, Braun, J��rgen, Coates, Laura C., Chandran, Vinod, Diekhoff, Torsten, van Gaalen, Floris A., Gensler, Lianne S., Goel, Niti, Gottlieb, Alice B., van der Heijde, D��sir��e, Helliwell, Philip S., Hermann, Kay Geert A., Jadon, Deepak, Lambert, Robert G., Maksymowych, Walter P., Mease, Philip, Nash, Peter, Proft, Fabian, Protopopov, Mikhail, Sieper, Joachim, Torgutalp, Murat, and Gladman, Dafna D.

Subjects
FOS: Clinical medicine, 110604 Sports Medicine, FOS: Health sciences, 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified, 110314 Orthopaedics
Abstract

Supplemental material, sj-docx-2-tab-10.1177_1759720X211057975 for Axial Involvement in Psoriatic Arthritis cohort (AXIS): the protocol of a joint project of the Assessment of SpondyloArthritis international Society (ASAS) and the Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA) by Denis Poddubnyy, Xenofon Baraliakos, Filip Van den Bosch, J��rgen Braun, Laura C. Coates, Vinod Chandran, Torsten Diekhoff, Floris A. van Gaalen, Lianne S. Gensler, Niti Goel, Alice B. Gottlieb, D��sir��e van der Heijde, Philip S. Helliwell, Kay Geert A. Hermann, Deepak Jadon, Robert G. Lambert, Walter P. Maksymowych, Philip Mease, Peter Nash, Fabian Proft, Mikhail Protopopov, Joachim Sieper, Murat Torgutalp and Dafna D. Gladman in Therapeutic Advances in Musculoskeletal Disease

Published
2021
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31. Deep learning for detection of radiographic sacroiliitis: achieving expert-level performance

Author

Bressem, Keno K., Vahldiek, Janis L., Adams, Lisa, Niehues, Stefan Markus, Haibel, Hildrun, Rodriguez, Valeria Rios, Torgutalp, Murat, Protopopov, Mikhail, Proft, Fabian, Rademacher, Judith, Sieper, Joachim, Rudwaleit, Martin, Hamm, Bernd, Makowski, Marcus R., Hermann, Kay-Geert, and Poddubnyy, Denis

Subjects
Research Article, Axial spondyloarthritis, Sacroiliitis, Artificial intelligence, Deep learning, Machine learning, ddc
Published
2020

32. Development and validation of an artificial intelligence approach for the detection of radiographic sacroiliitis

Author

Bressem, Keno-Kyrill, Vahldiek, Janis Lucas, Adams, Lisa, Niehues, Stefan M, Haibel, Hildrun, Rios Rodriguez, Valeria, Torgutalp, Murat, Protopopov, Mikhail, Proft, Fabian, Rademacher, Judith, Sieper, Joachim, Rudwaleit, Martin, Hamm, Bernd, Makowski, Markus, Hermann, Kay Geert A, and Poddubnyy, Denis

Abstract

Objectives: To develop and validate an artificial neural network for the detection of definite radiographic sacroiliitis as a manifestation of axial spondyloarthritis. Methods: Conventional radiographs of sacroiliac joints from two independent cohorts of patients with axial spondyloarthritis (axSpA) were used. The first cohort consisted of 1669 radiographs and was used for training and validation of a neural network. The second cohort consisted of 525 radiographs, of which 100 radiographs were randomly selected for the test dataset. In both cohorts all radiographs underwent central reading; the final decision on the presence or absence of definite radiographic sacroiliitis was used as a reference. For performance evaluation of the neural network, areas under the receiver operating characteristic curves (AUROC) were calculated. Sensitivity and specificity for the prediction cut-offs were calculated. Cohens Kappa and the absolute agreement were used to assess the agreement between the neural network and the human readers. Results: The neural network achieved an excellent performance in recognition of definite radiographic sacroiliitis with AUROC of 0.97 and 0.96 for the validation and test datasets, respectively. Sensitivity and specificity for the cut-off weighting both measurements equally were 0.90 and 0.93 for the validation and 0.87 and 0.97 for the test set. The Cohens kappa between the neural network and the reference judgements were 0.80 for both validation and test sets, and the absolute agreement on the classification yielded 91% and 90%, respectively. Conclusions: Artificial neural networks enable the accurate detection of definite radiographic sacroiliitis relevant for the diagnosis and classification of axSpA.

Published
2020
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33. Imaging assessment of children presenting with suspected or known juvenile idiopathic arthritis : ESSR-ESPR points to consider.

Author

Hemke, Robert, Herregods, Nele, Jaremko, Jacob L, Åström, Gunnar, Avenarius, Derk, Becce, Fabio, Bielecki, Dennis K, Boesen, Mikael, Dalili, Danoob, Giraudo, Chiara, Hermann, Kay-Geert, Humphries, Paul, Isaac, Amanda, Jurik, Anne Grethe, Klauser, Andrea S, Kvist, Ola, Laloo, Frederiek, Maas, Mario, Mester, Adam, Oei, Edwin, Offiah, Amaka C, Omoumi, Patrick, Papakonstantinou, Olympia, Plagou, Athena, Shelmerdine, Susan, Simoni, Paolo, Sudoł-Szopińska, Iwona, Tanturri de Horatio, Laura, Teh, James, Jans, Lennart, Rosendahl, Karen, Hemke, Robert, Herregods, Nele, Jaremko, Jacob L, Åström, Gunnar, Avenarius, Derk, Becce, Fabio, Bielecki, Dennis K, Boesen, Mikael, Dalili, Danoob, Giraudo, Chiara, Hermann, Kay-Geert, Humphries, Paul, Isaac, Amanda, Jurik, Anne Grethe, Klauser, Andrea S, Kvist, Ola, Laloo, Frederiek, Maas, Mario, Mester, Adam, Oei, Edwin, Offiah, Amaka C, Omoumi, Patrick, Papakonstantinou, Olympia, Plagou, Athena, Shelmerdine, Susan, Simoni, Paolo, Sudoł-Szopińska, Iwona, Tanturri de Horatio, Laura, Teh, James, Jans, Lennart, and Rosendahl, Karen

Abstract

Juvenile idiopathic arthritis (JIA) is the most common paediatric rheumatic disease. It represents a group of heterogenous inflammatory disorders with unknown origin and is a diagnosis of exclusion in which imaging plays an important role. JIA is defined as arthritis of one or more joints that begins before the age of 16 years, persists for more than 6 weeks and is of unknown aetiology and pathophysiology. The clinical goal is early suppression of inflammation to prevent irreversible joint damage which has shifted the emphasis from detecting established joint damage to proactively detecting inflammatory change. This drives the need for imaging techniques that are more sensitive than conventional radiography in the evaluation of inflammatory processes as well as early osteochondral change. Physical examination has limited reliability, even if performed by an experienced clinician, emphasising the importance of imaging to aid in clinical decision-making. On behalf of the European Society of Musculoskeletal Radiology (ESSR) arthritis subcommittee and the European Society of Paediatric Radiology (ESPR) musculoskeletal imaging taskforce, based on literature review and/or expert opinion, we discuss paediatric-specific imaging characteristics of the most commonly involved, in literature best documented and clinically important joints in JIA, namely the temporomandibular joints (TMJs), spine, sacroiliac (SI) joints, wrists, hips and knees, followed by a clinically applicable point to consider for each joint. We will also touch upon controversies in the current literature that remain to be resolved with ongoing research. KEY POINTS: • Juvenile idiopathic arthritis (JIA) is the most common chronic paediatric rheumatic disease and, in JIA imaging, is increasingly important to aid in clinical decision-making. • Conventional radiographs have a lower sensitivity and specificity for detection of disease activity and early destructive change, as compared to MRI or ultrasound. Nonet

Published
2020
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34. Axial Involvement in Psoriatic Arthritis cohort (AXIS): the protocol of a joint project of the Assessment of SpondyloArthritis international Society (ASAS) and the Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA)

Author

Poddubnyy, Denis, primary, Baraliakos, Xenofon, additional, Van den Bosch, Filip, additional, Braun, Jürgen, additional, Coates, Laura C., additional, Chandran, Vinod, additional, Diekhoff, Torsten, additional, van Gaalen, Floris A., additional, Gensler, Lianne S., additional, Goel, Niti, additional, Gottlieb, Alice B., additional, van der Heijde, Désirée, additional, Helliwell, Philip S., additional, Hermann, Kay Geert A., additional, Jadon, Deepak, additional, Lambert, Robert G., additional, Maksymowych, Walter P., additional, Mease, Philip, additional, Nash, Peter, additional, Proft, Fabian, additional, Protopopov, Mikhail, additional, Sieper, Joachim, additional, Torgutalp, Murat, additional, and Gladman, Dafna D., additional

Published
2021
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38. Radiographic Progression Is Associated With Resolution of Systemic Inflammation in Patients With Axial Spondylarthritis Treated With Tumor Necrosis Factor α Inhibitors: a Study of Radiographic Progression, Inflammation on Magnetic Resonance Imaging, and Circulating Biomarkers of Inflammation, Angiogenesis, and Cartilage and Bone Turnover

Author

Pedersen, Susanne Juhl, Srensen, Inge Juul, Lambert, Robert G. W., Hermann, Kay-Geert A., Garnero, Patrick, Johansen, Julia Sidenius, Madsen, Ole Rintek, Hansen, Annette, Hansen, Michael Sejer, Thamsborg, Gorm, Andersen, Lis Smedegaard, Majgaard, Ole, Loft, Anne Gitte, Erlendsson, Jon, Asmussen, Karsten H., Jurik, Anne Grethe, Mller, Jakob, Hasselquist, Maria, Mikkelsen, Dorrit, and stergaard, Mikkel

Published
2011
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39. Clinical and imaging characteristics of osteitis condensans ilii as compared with axial spondyloarthritis

Author

Poddubnyy, Denis, primary, Weineck, Henning, additional, Diekhoff, Torsten, additional, Redeker, Imke, additional, Gobejishvili, Nino, additional, Llop, Maria, additional, Rodriguez, Valeria Rios, additional, Proft, Fabian, additional, Protopopov, Mikhail, additional, Haibel, Hildrun, additional, Sieper, Joachim, additional, and Hermann, Kay Geert A, additional

Published
2020
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41. Joint anatomy in axial spondyloarthritis: strong associations between sacroiliac joint form variation and symptomatic disease.

Author

Ziegeler, Katharina, Kreutzinger, Virginie, Proft, Fabian, Poddubnyy, Denis, Hermann, Kay Geert A, and Diekhoff, Torsten

Subjects
SACROILIAC joint, CROSS-sectional method, COMPARATIVE studies, SEX distribution, DIAGNOSTIC imaging, DISEASE prevalence, COMPUTED tomography
Abstract

Objectives The aim of this investigation was to determine the prevalence of variant SI joint forms in symptomatic patients with mechanical joint disease (MJD) and axial SpA (axSpA) compared with control patients. Method A total of 973 patients were included in this cross-sectional study (95 axSpA; 61 MJD; 817 controls); clinical diagnosis, age and gender were noted. An established scoring system was used to classify joint forms on CT scans of the pelvis. Frequencies of joint forms were compared between groups (axSpA; MJD; controls). Results Patients with MJD exhibited the highest proportion of atypical joints (80.3% in MJD vs 44.1% in axSpA and 37.5% in controls; P  < 0.001). Overall, females had a significantly higher proportion of atypical joints than men (65.0 vs 17.8%; P < 0.001); proportions of atypical joints were significantly higher in males with symptomatic joint disease than in male controls: 32.2% in axSpA, 55.0% in MJD and 13.9% in controls; P  ≤ 0.001. Two specific joint forms were significantly more prevalent in symptomatic patients than in controls: the iliosacral complex (16.2 vs 4.2%; P  < 0.001) and the crescent-shaped ilium (9.1 vs 2.8%; P  < 0.05). Conclusions Our data demonstrate a strong association between atypical joint forms and symptomatic joint disease. [ABSTRACT FROM AUTHOR]

Published
2022
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42. Development and Validation of an OMERACT MRI Whole-Body Score for Inflammation in Peripheral Joints and Entheses in Inflammatory Arthritis (MRI-WIPE)

Author

Krabbe, Simon, Eshed, Iris, Gandjbakhch, Frédérique, Pedersen, Susanne J, Bird, Paul, Mathew, Ashish J, Lambert, Robert G, Maksymowych, Walter P, Glinatsi, Daniel, Stoenoiu, Maria, Poggenborg, René, Jans, Lennart, Jaremko, Jacob L, Herregods, Nele, Foltz, Violaine, Conaghan, Philip G, Althoff, Christian E, Paschke, Joel, Peterfy, Charles, Hermann, Kay-Geert A, Østergaard, Mikkel, OMERACT MRI in Arthritis Working Group, UCL - SSS/IREC/RUMA - Pôle de Pathologies rhumatismales, and UCL - (SLuc) Service de rhumatologie

Subjects
medicine.medical_specialty, Inflammatory arthritis, Immunology, Arthritis, Enthesopathy, 030218 nuclear medicine & medical imaging, Arthritis, Rheumatoid, 03 medical and health sciences, 0302 clinical medicine, Magnetic resonance imaging, Rheumatology, Internal medicine, Synovitis, medicine, Immunology and Allergy, Humans, Whole Body Imaging, 030203 arthritis & rheumatology, Inflammation, medicine.diagnostic_test, business.industry, Enthesitis, Reproducibility of Results, medicine.disease, Enthesis, Magnetic Resonance Imaging, Outcome assessment, Radiology, medicine.symptom, Osteitis, business, Omeract
Abstract

Objective.To develop a whole-body magnetic resonance imaging (MRI) scoring system for peripheral arthritis and enthesitis.Methods.After consensus on definitions/locations of MRI pathologies, 4 multireader exercises were performed. Eighty-three joints were scored 0–3 separately for synovitis and osteitis, and 33 entheses 0–3 separately for soft tissue inflammation and osteitis.Results.In the last exercise, reliability was moderate-good for musculoskeletal radiologists and rheumatologists with previously demonstrated good scoring proficiency. Median pairwise single-measure/average-measure ICC were 0.67/0.80 for status scores and 0.69/0.82 for change scores; κ ranged 0.35–0.77.Conclusion.Whole-body MRI scoring of peripheral arthritis and enthesitis is reliable, which encourages further testing and refinement in clinical trials.

Published
2019

43. Identification of a typical pattern of MRI lesions of sacroiliac joints in patients with osteitis condensans ilii as compared to axial spondyloarthritis

Author

Poddubnyy, Denis, Gobejishvili, Nino, Diekhoff, Torsten, Weineck, Henning, Llop, Maria, Rios Rodriguez, Valeria, Sieper, Joachim, and Hermann, Kay-Geert

Subjects
musculoskeletal diseases, ddc: 610, 610 Medical sciences, Medicine
Abstract

Background: Osteitis condensans ilii (OCI) is regarded as a non-inflammatory disorder that is believed to be induced, for example, by mechanical stress and mechanical instability of the sacroiliac joints (SIJ) related to pregnancy/delivery. OCI is being increasingly recognized as an important differential[for full text, please go to the a.m. URL], 46. Kongress der Deutschen Gesellschaft für Rheumatologie (DGRh), 32. Jahrestagung der Deutschen Gesellschaft für Orthopädische Rheumatologie (DGORh), Wissenschaftliche Herbsttagung der Gesellschaft für Kinder- und Jugendrheumatologie (GKJR)

Published
2019

44. Similarities and differences between osteitis condensans ilii and axial spondyloarthritis patients presenting with chronic back pain in a rheumatology setting

Author

Poddubnyy, Denis, Weineck, Henning, Listing, Joachim, Diekhoff, Torsten, Hermann, Kay-Geert, and Sieper, Joachim

Subjects
musculoskeletal diseases, ddc: 610, 610 Medical sciences, Medicine
Abstract

Background: Osteitis condensans ilii (OCI) is regarded as a non-inflammatory disorder, which is considered to be induced by mechanical stress (e.g., by pregnancy and delivery). The diagnosis is normally based on wide spread sclerosis of the sacroiliac joint without erosions or ankyloses on imaging. [for full text, please go to the a.m. URL], 46. Kongress der Deutschen Gesellschaft für Rheumatologie (DGRh), 32. Jahrestagung der Deutschen Gesellschaft für Orthopädische Rheumatologie (DGORh), Wissenschaftliche Herbsttagung der Gesellschaft für Kinder- und Jugendrheumatologie (GKJR)

Published
2019

50. The OMERACT MRI in enthesitis initiative:Definitions of key pathologies, suggested MRI sequences, and a novel heel enthesitis scoring system

Author

Mathew, Ashish J., Krabbe, Simon, Eshed, Iris, Gandjbakhch, Frédérique, Bird, Paul, Pedersen, Susanne J., Stoenoiu, Maria S., Foltz, Violaine, Glinatsi, Daniel, Lambert, Robert G., Hermann, Kay Geert A., Maksymowych, Walter P., Haugen, Ida K., Jaremko, Jacob L., Poggenborg, René P., Paschke, Joel, Laredo, Jean Denis, Carron, Philippe, Conaghan, Philip G., Østergaard, Mikkel, Mathew, Ashish J., Krabbe, Simon, Eshed, Iris, Gandjbakhch, Frédérique, Bird, Paul, Pedersen, Susanne J., Stoenoiu, Maria S., Foltz, Violaine, Glinatsi, Daniel, Lambert, Robert G., Hermann, Kay Geert A., Maksymowych, Walter P., Haugen, Ida K., Jaremko, Jacob L., Poggenborg, René P., Paschke, Joel, Laredo, Jean Denis, Carron, Philippe, Conaghan, Philip G., and Østergaard, Mikkel

Abstract

Objective. To develop and validate an enthesitis magnetic resonance imaging (MRI) scoring system for spondyloarthritis/psoriatic arthritis, using the heel as model. Methods. Consensus definitions of key pathologies and 3 heel enthesitis multireader scoring exercises were done, separated by discussion, training, and calibration. Results. Definitions for bone and soft tissue pathologies were agreed. In the final exercise, median pairwise single-measures intraclass correlation coefficients (ICC; patient-level) for entheseal inflammation status/change scores were 0.83/0.82 for all readers. For radiologists and selected rheumatologists, ICC were 0.91/0.84 and quadratic-weighted κ (lesion-level) 0.57-0.91/0.45-0.81. Conclusion. The proposed definitions and Heel Enthesitis Scoring System (HEMRIS) are reliable among trained readers and promising for clinical trials.

Published
2019

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