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2. Multicenter, Prospective, Randomized Controlled Trial of High-Sensitivity Cardiac Troponin I–Guided Combination Angiotensin Receptor Blockade and Beta-Blocker Therapy to Prevent Anthracycline Cardiotoxicity: The Cardiac CARE Trial

Author

Henriksen, Peter A., Hall, Peter, MacPherson, Iain R., Joshi, Shruti S., Singh, Trisha, Maclean, Morag, Lewis, Steff, Rodriguez, Aryelly, Fletcher, Alex, Everett, Russell J., Stavert, Harriet, Broom, Angus, Eddie, Lois, Primrose, Lorraine, McVicars, Heather, McKay, Pam, Borley, Annabel, Rowntree, Clare, Lord, Simon, Collins, Graham, Radford, John, Guppy, Amy, Williams, Michelle C., Japp, Alan, Payne, John R., Newby, David E., Mills, Nick L., Oikonomidou, Olga, and Lang, Ninian N.

Published
2023
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7. Sex Differences in Revascularization, Treatment Goals, and Outcomes of Patients With Chronic Coronary Disease: Insights From the ISCHEMIA Trial

Author

Reynolds, Harmony R., primary, Cyr, Derek D., additional, Merz, C. Noel Bairey, additional, Shaw, Leslee J., additional, Chaitman, Bernard R., additional, Boden, William E., additional, Alexander, Karen P., additional, Rosenberg, Yves D., additional, Bangalore, Sripal, additional, Stone, Gregg W., additional, Held, Claes, additional, Spertus, John, additional, Goetschalckx, Kaatje, additional, Bockeria, Olga, additional, Newman, Jonathan D., additional, Berger, Jeffrey S., additional, Elghamaz, Ahmed, additional, Lopes, Renato D., additional, Min, James K., additional, Berman, Daniel S., additional, Picard, Michael H., additional, Kwong, Raymond Y., additional, Harrington, Robert A., additional, Thomas, Boban, additional, O'Brien, Sean M., additional, Maron, David J., additional, Hochman, Judith S., additional, Mavromatis, Kreton, additional, Linefsky, Jason, additional, Miller, Todd, additional, Banerjee, Subhash, additional, Reynolds, Harmony R., additional, Donnino, Robert M., additional, Phillips, Lawrence M., additional, Saric, Muhamed, additional, Abdul‐Nour, Khaled, additional, Stone, Peter H., additional, Jang, James J., additional, Yee, Gennie, additional, Weitz, Steven, additional, Arnold, Suzanne, additional, O’Keefe, James Henry, additional, Shapiro, Michael D., additional, El‐Hajjar, Mohammad, additional, Sidhu, Mandeep S., additional, Fein, Steven A., additional, Torosoff, Mikhail T., additional, Lyubarova, Radmila, additional, Mookherjee, Sulagna, additional, Drzymalski, Krzysztof, additional, McFalls, Edward O., additional, Garcia, Santiago A., additional, Bertog, Stefan C., additional, Siddiqui, Rizwan A., additional, Ishani, Areef, additional, Hansen, Ronnell A., additional, Khouri, Michel Georges, additional, Goldberg, Jonathan L., additional, Goldweit, Richard, additional, Cohen, Ronny A., additional, Mirrer, Brooks, additional, Navarro, Victor, additional, Winchester, David E., additional, Kronenberg, Marvin, additional, Rogal, Philip, additional, McFarren, Christopher, additional, Heitner, John F., additional, Dauber, Ira M., additional, Cannan, Charles, additional, Sudarshan, Sriram, additional, Mehta, Puja K., additional, McDaniel, Michael, additional, Lerakis, Stamatios, additional, Quyyumi, Arshed, additional, Wenger, Nanette K., additional, Hedgepeth, Chester M., additional, Hurlburt, Heather, additional, Rosen, Alan, additional, Sahul, Zakir, additional, Booth, David, additional, Leung, Steve, additional, Abdel‐Latif, Ahmed, additional, Reda, Hassan, additional, Ziada, Khaled, additional, Setty, Sampoornima, additional, Barua, Rajat S., additional, Hage, Fadi, additional, Caldeira, Christiano, additional, Davies, James E., additional, Leesar, Massoud, additional, Heo, Jaekyeong, additional, Iskandrian, Amy, additional, Al Solaiman, Firas, additional, Singh, Satinder, additional, Dajani, Khaled, additional, Der Mesropian, Paul, additional, Sacco, Joseph, additional, McCandless, Brian, additional, Orgera, Marisa, additional, Arif, Imran, additional, Kerr, Hanan, additional, Trejo (Gutierrez), Jorge F., additional, Fletcher, Gerald, additional, Lane, Gary E., additional, Neeson, Lynn M., additional, Parikh, Pragnesh P., additional, Pollak, Peter M., additional, Shapiro, Brian P., additional, Landolfo, Kevin, additional, Gemignani, Anthony, additional, O’Rourke, Daniel, additional, Meadows, Judith L., additional, Call, Jason T., additional, Hannan, Joseph, additional, Bojar, Robert, additional, Kumar, Deepti, additional, Mukai, John, additional, Martin, Edward T., additional, Vorobiof, Gabriel, additional, Moorman, Alec, additional, Kinlay, Scott, additional, Hamburger, Robert J., additional, Rocco, Thomas P., additional, Bhatt, Deepak L., additional, Croce, Kevin, additional, Quin, Jacquelyn A., additional, Anumpa, Jati, additional, Zenati, Marco, additional, Faxon, David P., additional, Rayos, Glenn, additional, Seedhom, Ashraf, additional, Sullenberger, Lance, additional, Kumkumian, Gregory, additional, Sedlis, Steven P., additional, Donnino, Robert M., additional, Lorin, Jeffrey, additional, Tamis‐Holland, Jacqueline E., additional, Kornberg, Robert, additional, Leber, Robert, additional, Saba, Souheil, additional, Lee, Michael W., additional, Small, Delano R., additional, Nona, Wassim, additional, Alexander, Patrick B., additional, Rehman, Iram, additional, Badami, Umesh, additional, Marzo, Kevin, additional, Robbins, Inga H., additional, Levite, Howard A., additional, Shetty, Sanjay, additional, Patel, Mayuri, additional, Hamroff, Glenn S., additional, Little, Raymond W., additional, Zimbelman, Brandi D., additional, Lui, Charles Y., additional, Smith, Brigham R., additional, Vezina, Daniel P., additional, Khor, Lillian L., additional, Abraham, Josephine D., additional, Bull, David A., additional, McKellar, Stephen H., additional, Kotter, John, additional, Hu, Bob, additional, Labovitz, Arthur J., additional, Berlowitz, Michael, additional, Matar, Fadi, additional, Rodriguez, Fatima, additional, Schnittger, Ingela, additional, Fearon, William F., additional, Deedwania, Prakash, additional, Reddy, Kiran, additional, Sweeny, Joseph, additional, Spizzieri, Christopher, additional, Hochberg, Claudia P., additional, Salerno, William D., additional, Wyman, Ray, additional, Zarka, Amer, additional, Shah, Anil V., additional, Haldis, Thomas, additional, Kohn, Jeffrey A., additional, Girotra, Saket, additional, Almousalli, Omar, additional, Krishnam, Mayil S., additional, Milliken, Jeffrey C., additional, Patel, Pranav M., additional, Seto, Arnold H., additional, Harley, Kevin T., additional, Gibson, Michael A., additional, Allen, Byron J., additional, Coram, Rita, additional, Thomas, Sabu, additional, Schwartz, Ronald G., additional, Chen, Wei, additional, El Shahawy, Mahfouz, additional, Stafford, James, additional, Abernethy, William B., additional, Zurick, Andrew, additional, Meyer, Thomas M., additional, Morford, Ronald G., additional, Rutkin, Bruce, additional, Bokhari, Sabahat, additional, Sokol, Seth I., additional, Meisner, Jay, additional, Hamzeh, Ihab, additional, Misra, Arunima, additional, Wall, Matthew, additional, De Rosen, Veronica Lenges, additional, Alam, Mahboob, additional, Turner, Michael C., additional, Mulhearn, Thomas J., additional, Good, Arnold P., additional, Shammas, Nicolas W., additional, Chilton, Robert, additional, Nguyen, Patricia K., additional, Jezior, Matthew, additional, Gordon, Paul C., additional, Crain, Thomas, additional, Stenberg, Robert, additional, Pedalino, Ronald P., additional, Wiesel, Joseph, additional, Juang, George J., additional, Al‐Amoodi, Mohammed, additional, Wohns, David, additional, Lader, Ellis W., additional, Mumma, Michael, additional, Dharmarajan, Lekshmi, additional, McGarvey, Joseph F. X., additional, Downes, Thomas R., additional, Luckasen, Gary J., additional, Cheong, Benjamin, additional, Potluri, Srinivasa, additional, Mastouri, Ronald A., additional, Breall, Jeffery A., additional, Revtyak, George E., additional, Bazeley, Jonathan W., additional, Li, Dayuan, additional, Giedd, Kenneth, additional, Old, Wayne, additional, Burt, Francis, additional, Sokhon, Kozhaya, additional, Gopal, Deepika, additional, Valeti, Uma S., additional, Kobashigawa, Jon, additional, Govindan, Sajeev Chakanalil, additional, Nair, Rajesh Gopalan, additional, Manjunath, Cholenahally Nanjappa, additional, Moorthy, Nagaraja, additional, Manjunath, Satvic Cholenahally, additional, Narayanappa, Suryaprakash, additional, Pandit, Neeraj, additional, Nath, Ranjit Kumar, additional, Dwivedi, S. K., additional, Narain, V. S., additional, Chandra, Sharad, additional, Wander, Gurpreet S., additional, Tandon, Rohit, additional, Ralhan, Sarju, additional, Aslam, Naved, additional, Goyal, Abhishek, additional, Bhargava, Balram, additional, Karthikeyan, G., additional, Ramakrishnan, S., additional, Seth, Sandeep, additional, Yadav, Rakesh, additional, Singh, Sandeep, additional, Roy, Ambuj, additional, Parakh, Neeraj, additional, Verma, Sunil Kumar, additional, Narang, Rajiv, additional, Mishra, Sundeep, additional, Naik, Nitish, additional, Sharma, Gautam, additional, Choudhary, Shiv Kumar, additional, Patel, Chetan, additional, Gulati, Gurpreet, additional, Sharma, Sanjeev, additional, Bahl, V. K., additional, Mathew, Anoop, additional, Punnoose, Eapen, additional, Gadkari, Milind Avdhoot, additional, Gadage, Siddharth, additional, Pillay, Tapan Umesh, additional, Satheesh, Santhosh, additional, Mathur, Atul, additional, Kaul, Upendra, additional, Christopher, Johann, additional, Menon, Rajeev, additional, Kumar, Nirmal, additional, Oomman, Abraham, additional, Mao, Robert, additional, Solomon, Hilda, additional, Naik, Sudhir, additional, Khan, Sajeeda Parveen, additional, Grant, Purvez, additional, Kachru, Ranjan, additional, Ajit Kumar, V. K., additional, Ganapathi, Sanjay, additional, Jayakumar, K., additional, Sivadasanpillai, Harikrishnan, additional, Sasidharan, Bijulal, additional, Kapilamoorthy, T. R., additional, Polamuri, Praneeth, additional, Senior, Roxy, additional, Gurunathan, Sothinathan, additional, Karogiannis, Nikolaos, additional, Shah, Benoy N., additional, Trimlett, Richard HJ, additional, Rubens, Michael B., additional, Nicol, Edward D., additional, Mittal, Tarun K., additional, Hampson, Reinette, additional, Gamma, Reto Andreas, additional, de Belder, Mark A., additional, Thambyrajah, Jeet, additional, Nageh, Thuraia, additional, Davies, John R., additional, Lindsay, Steven J., additional, Kurian, John, additional, Jamil, Haqeel, additional, Raheem, Osama, additional, Hoye, Angela, additional, Donnelly, Patrick, additional, Valecka, Bernardas, additional, Chauhan, Anoop, additional, Barr, Craig, additional, Alfakih, Khaled, additional, Byrne, Jonathan, additional, Webb, Ian, additional, Henriksen, Peter, additional, OKane, Peter, additional, de Silva, Ramesh, additional, Conway, Dwayne S. G., additional, Sirker, Alexander A, additional, Hoole, Stephen P., additional, Witherow, Fraser N., additional, Johnston, Nicola, additional, Harbinson, Mark, additional, Walsh, Simon, additional, Douglas, Hanna, additional, Luckie, Matthew, additional, Sobolewska, Jolanta, additional, Jeetley, Paramjit, additional, Patel, Niket, additional, Kotecha, Tushar, additional, Travill, Christopher, additional, Karimullah, Iqbal, additional, Al‐Bustami, Mahmud, additional, Braganza, Denise, additional, Henderson, Robert, additional, Pointon, Kate, additional, Naik, Surendra, additional, Mathew, Thomas, additional, Berry, Colin, additional, Collison, Damien, additional, Roditi, Giles, additional, Moriarty, Andrew J., additional, Glover, Jason D., additional, Pradhan, Jiwan, additional, Mikhail, Ghada, additional, Francis, Darrel P., additional, Gosselin, Gilbert, additional, Diaz, Ariel, additional, Rheault, Philippe, additional, Barrero, Miguel, additional, Gagné, Carl‐Éric, additional, Pépin‐Dubois, Yanek, additional, Costa, Ricardo, additional, Sia, Ying Tung, additional, Lemay, Catherine, additional, Gisbert, Alejandro, additional, Gervais, Pierre, additional, Rheault, Alain, additional, Phaneuf, Denis Carl, additional, Garg, Pallav, additional, Chow, Benjamin J. W., additional, Hessian, Renee C., additional, Beanlands, Rob S., additional, Davies, Richard F., additional, Bainey, Kevin R., additional, Cheema, Asim N., additional, Bagai, Akshay, additional, Wald, Ron, additional, Goodman, Shaun, additional, Graham, John Joseph, additional, Peterson, Mark, additional, Chow, Chi‐Ming, additional, Abramson, Beth, additional, Cheema, Asim Nazir, additional, Vakani, Mohammad Tariq, additional, Cha, James, additional, Howarth, Andrew G, additional, Wong, Graham, additional, Uxa, Amar, additional, Galiwango, Paul, additional, Kassam, Saleem, additional, Mukherjee, Ashok, additional, Ricci, A. Joseph, additional, Lam, Andy, additional, Mehta, Shamir, additional, Udell, Jacob, additional, Généreux, Philippe, additional, Hameed, Adnan, additional, Daba, Ledjalem, additional, Hueb, Whady, additional, Rezende, Paulo Cury, additional, Silva, Expedito Eustáquio Ribeiro, additional, Hueb, Alexandre Ciappina, additional, Smanio, Paola Emanuela Poggio, additional, de Quadros, Alexandre Schaan, additional, Kalil, Renato Abdala Karam, additional, da Costa Vieira, José Luiz, additional, Grossmann, Gabriel, additional, de Oliveira, Pedro Píccaro, additional, Bridi, Leonardo, additional, Savaris, Simone, additional, Vitola, João V., additional, Cerci, Rodrigo J., additional, Farias, Fabio R., additional, Fernandes, Miguel M., additional, Marin‐Neto, José Antonio, additional, Schmidt, André, additional, de Oliveira Lima Filho, Moysés, additional, Oliveira, Ricardo Mendes, additional, Chierice, João Reynaldo Abbud, additional, Polanczyk, Carísi A., additional, Furtado, Mariana V., additional, Smidt, Luis F., additional, Carvalho, Antonio Carlos, additional, Pucci, Gustavo, additional, Lyra, Flavio, additional, Junior, Alvaro Rabelo Alves, additional, Dracoulakis, Marianna D. A., additional, Lima, Rodolfo G. S. D, additional, Figueiredo, Estevao, additional, Caramori, Paulo Ricardo, additional, Tumelero, Rogerio, additional, Dall’Orto, Frederico, additional, Mesquita, Claudio T., additional, Colafranseschi, Alexandre S., additional, Oliveira, Amarino C., additional, Carvalho, Luiz A., additional, Palazzo, Isabella C., additional, Sousa, Andre S., additional, da Silva, Expedito Eustáquio Ribeiro, additional, de Barros, Pedro Gabriel Melo, additional, de Pádua Silva Baptista, Luciana, additional, Rodrigues, Marcelo Jamus, additional, de Resende, Marcos Valério Coimbra, additional, Saraiva, Jose Francisco, additional, Costantini, Costantino, additional, Demkow, Marcin, additional, Pracon, Radoslaw, additional, Kepka, Cezary, additional, Teresinska, Anna, additional, Kryczka, Karolina, additional, Henzel, Jan, additional, Solecki, Mateusz, additional, Kaczmarska, Edyta, additional, Mazurek, Tomasz, additional, Drozdz, Jaroslaw, additional, Czarniak, Bartosz, additional, Frach, Malgorzata, additional, Szymczyk, Konrad, additional, Niedzwiecka, Iwona, additional, Sobczak, Sebastian, additional, Ciurus, Tomasz, additional, Jakubowski, Piotr, additional, Misztal‐Teodorczyk, Magdalena, additional, Teodorczyk, Dawid, additional, Fratczak, Aleksandra, additional, Szkopiak, Marcin, additional, Lebioda, Patrycja, additional, Wlodarczyk, Michal, additional, Plachcinska, Anna, additional, Kusmierek, Jacek, additional, Miller, Magdalena, additional, Marciniak, Halina, additional, Wojtczak‐Soska, Karolina, additional, Luczak, Katarzyna, additional, Tarchalski, Tomasz, additional, Cichocka‐Radwan, Anna, additional, Szwed, Hanna, additional, Szulczyk, Grazyna Anna, additional, Witkowski, Adam, additional, Kukula, Krzysztof, additional, Celinska‐Spodar, Malgorzta, additional, Zalewska, Joanna, additional, Gajos, Grzegorz, additional, Bury, Krzysztof, additional, Pruszczyk, Piotr, additional, Roik, Marek, additional, Loboz‐Grudzien, Krystyna, additional, Sokalski, Leszek, additional, Brzezinska, Barbara, additional, Lesiak, Maciej, additional, Lanocha, Magdalena, additional, Reczuch, Krzysztof W., additional, Kalarus, Zbigniew, additional, Swiatkowski, Andrzej, additional, Szulik, Mariola, additional, Musial, Wlodzimierz J., additional, Bockeria, Leo, additional, Petrosyan, Karen, additional, Trifonova, Tatiana, additional, Chernyavskiy, Alexander M., additional, Kretov, Evgeniy I., additional, Grazhdankin, Igor O., additional, Bershtein, Leonid L., additional, Sayganov, Sergey A., additional, Kuzmina‐Krutetskaya, Anastasia M., additional, Zbyshevskaya, Elizaveta V., additional, Katamadze, Nana O., additional, Demchenko, Elena A., additional, Kozlov, Pavel S., additional, Kozulin, Vikentiy Y., additional, Lubinskaya, Ekaterina I., additional, Lopez‐Sendon, Jose, additional, Castro, Almudena, additional, Salicio, Elena Refoyo, additional, Guzman, Gabriela, additional, Galeote, Gabriel, additional, Valbuena, Silvia, additional, Peteiro, Jesús, additional, Martínez‐Ruíz, María Dolores, additional, Pérez‐Fernández, Ruth, additional, Cuenca‐Castillo, José J., additional, Flores‐Ríos, Xacobe, additional, Prada‐Delgado, Óscar, additional, Barge‐Caballero, Gonzalo, additional, Juanatey, Jose Ramon Gonzalez, additional, Bayarri, Miguel Souto, additional, Nuñez, Virginia Pubull, additional, Sanchez, Raymundo Ocaranza, additional, Alvarez, Belen Cid, additional, Gil, Carlos Peña, additional, Monzonis, Amparo Martinez, additional, Sionis, Alessandro, additional, Perales, Montserrat Vila, additional, Padró, Josep Maria, additional, Peñaranda, Antonio Serra, additional, Picart, Joan García, additional, Iglesias, Antonino Ginel, additional, Marimon, Xavier Garcia‐Moll, additional, Lladó, Guillem Pons, additional, Costa, Francesc Carreras, additional, Miro, Vicente, additional, Diez, Jose L., additional, Calvillo, Pilar, additional, Ortuño, F. Marin, additional, Chávarri, M. Valdés, additional, Montolliu, A. Tello, additional, Bermudez, E. Pinar, additional, De La Morena, G., additional, Blancas, Montserrat Gracida, additional, Luena, Jose Enrique Castillo, additional, Fernandez‐Aviles, Francisco, additional, Chen, Jiyan, additional, Wu, Yongjian, additional, Ma, Yitong, additional, Yang, Yining, additional, Ji, Zheng, additional, Yang, Xinchun, additional, Lin, Wenhua, additional, Zeng, Hesong, additional, Fu, Xin, additional, Yang, Bin, additional, Wang, Songtao, additional, Cheng, Gong, additional, Zhao, Yulan, additional, Fang, Xuehua, additional, Zeng, Qiutang, additional, Su, Xi, additional, Li, Qingxian, additional, Nie, Shao‐ping, additional, Yu, Qin, additional, Wang, Jian’an, additional, Zhang, Shuyang, additional, Liu, Zhenyu, additional, Perna, Gian Piero, additional, Marini, Marco, additional, Gabrielli, Gabriele, additional, Provasoli, Stefano, additional, Verna, Edoardo, additional, Monti, Lorenzo, additional, Nardi, Barbara, additional, Di Chiara, Antonio, additional, Mortara, Andrea, additional, Galvani, Marcello, additional, Ottani, Filippo, additional, Sicuro, Marco, additional, Calabro, Paolo, additional, Formisano, Tiziana, additional, Tarantini, Giuseppe, additional, Cucchini, Umberto, additional, Andres, Anto Luigi, additional, Racca, Emanuela, additional, Briguori, Carlo, additional, Amati, Roberto, additional, Vergoni, William, additional, Russo, Aldo, additional, Fanelli, Raffaele, additional, Poh, Kian‐Keong, additional, Chai, Ping, additional, Lau, Titus, additional, Loh, Joshua P., additional, Tay, Edgar L., additional, Teoh, Kristine, additional, Teo, Lynette L., additional, Ong, Ching‐Ching, additional, Wong, Raymond C., additional, Loh, Poay‐Huan, additional, Kofidis, Theodoros, additional, Chan, Wan Xian, additional, Chan, Koo Hui, additional, Foo, David, additional, Kong, Jason Loh Kwok, additional, Er, Ching Min, additional, Jafary, Fahim Haider, additional, Chua, Terrance, additional, Doerr, Rolf, additional, Stumpf, Juergen, additional, Matschke, Klaus, additional, Simonis, Gregor, additional, Kadalie, Clemens T., additional, Sechtem, Udo, additional, Ong, Peter, additional, Schulze, P. Christian, additional, Goebel, Bjoern, additional, Lenk, Karsten, additional, Nickenig, Georg, additional, Schuchlenz, Herwig, additional, Weikl, Stefan, additional, Lang, Irene Marthe, additional, Huber, Kurt, additional, Jakl‐Kotauschek, Gabriele, additional, Vertes, Andras, additional, Varga, Albert, additional, Fontos, Geza, additional, Merkely, Bela, additional, Kerecsen, Gabor, additional, Hinic, Sasa, additional, Zdravkovic, Marija, additional, Mudrenovic, Vladan, additional, Crnokrak, Bogdan, additional, Beleslin, Branko D., additional, Boskovic, Nikola N., additional, Petrovic, Marija T., additional, Dobric, Milan R., additional, Markovic, Zeljko Z., additional, Mladenovic, Ana S., additional, Cemerlic‐Adjic, Nada, additional, Davidovic, Goran, additional, Vucic, Rada, additional, Dekleva, Milica Nikola, additional, Stankovic, Goran, additional, Apostolovic, Svetlana, additional, Escobedo, Jorge, additional, Baleón‐Espinosa, Rubén, additional, Campos‐Santaolalla, Arturo S., additional, Durán‐Cortés, Elihú, additional, Flores‐Palacios, José M., additional, García‐Rincón, Andrés, additional, Jiménez‐Santos, Moisés, additional, Peñafiel, Joaquín V., additional, Ortega‐Ramírez, José A., additional, Valdespino‐Estrada, Aquiles, additional, Rosas, Erick Alexánderson, additional, Selvanayagam, Joseph B., additional, Joseph, Majo X., additional, Thambar, Suku T., additional, Beltrame, John F., additional, Hillis, Graham S., additional, Thuaire, Christophe, additional, Dutoiu, Téodora, additional, Steg, Philippe Gabriel, additional, Juliard, Jean‐Michel, additional, Slama, Michel S., additional, El Mahmoud, Rami, additional, Nicollet, Eric, additional, Goube, Pascal, additional, Barone‐Rochette, Gilles, additional, Furber, Alain, additional, Bière, Loïc, additional, Laucevicius, Aleksandras, additional, Celutkiene, Jelena, additional, Kedhi, Elvin, additional, Timmer, Jorik, additional, Hermanides, Rik, additional, Kaplan, Eliza, additional, Riezebos, Robert K., additional, Samadi, Pouneh, additional, van Dongen, Elise, additional, Niehe, Sander R., additional, Suryapranata, Harry, additional, van Vugt, Stijn, additional, Ramos, Ruben, additional, Cacela, Duarte, additional, Santana, Ana, additional, Fiarresga, Antonio, additional, Sousa, Lidia, additional, Marques, Hugo, additional, Patricio, Lino, additional, Bernanrdes, Luis, additional, Rio, Pedro, additional, Carvalho, Ramiro, additional, Ferreira, Rui, additional, Silva, Tiago, additional, Rodrigues, Ines, additional, Modas, Pedro, additional, Portugal, Guilherme, additional, Fragata, Jose, additional, Pinto, Fausto J., additional, Menezes, Miguel Nobre, additional, Lopes, Guilhermina Cantinho, additional, Almeida, Ana Gomes, additional, Silva, Pedro Canas, additional, Nobre, Angelo, additional, Francisco, Ana Rita, additional, Ferreira, Nuno, additional, Lopes, Ricardo L., additional, Guzman, Luis, additional, Figal, Julio César, additional, Méndiz, Oscar, additional, Cortés, Claudia, additional, Favaloro, Roberto René, additional, Alvarez, Carlos, additional, Courtis, Javier, additional, Zeballos, Gabriela, additional, Schiavi, Lilia, additional, Rubio, Mariano, additional, Devlin, Gerard Patrick, additional, Fisher, Raewyn, additional, Stewart, Ralph Alan Huston, additional, White, Harvey Douglas, additional, Benatar, Jocelyne, additional, Kedev, Sasko, additional, Mitevska, Irena Peovska, additional, Kostovska, Elizabeta Srbinovska, additional, Pejkov, Hristo, additional, Eggers, Kai, additional, Frostfelt, Gunnar, additional, Johnston, Nina, additional, Olsowka, Maciej, additional, Åkerblom, Axel, additional, Soveri, Inga, additional, Aspberg, Johannes, additional, Sharir, Tali, additional, Elian, Dan, additional, Kerner, Arthur, additional, Massalha, Samia, additional, Fukuda, Keiichi, additional, Kohsaka, Shun, additional, Yasuda, Satoshi, additional, Nishimura, Shigeyuki, additional, Van de Werf, Frans, additional, Claes, Kathleen, additional, Hung, Chung‐Lieh, additional, Yun, Chun‐Ho, additional, Hou, Charles Jia‐Yin, additional, Kuo, Jen‐Yuan, additional, Yeh, Hung‐I, additional, Hung, Ta‐Chuan, additional, Li, Jiun‐Yi, additional, Chien, Chen‐Yen, additional, Tsai, Cheng‐Ting, additional, Liu, Chun‐Chieh, additional, Yu, Fa‐Chang, additional, Lin, Yueh‐Hung, additional, Lan, Wei‐Ren, additional, Yen, Chih‐Hsuan, additional, Tsai, Jui‐Peng, additional, Sung, Kuo‐Tzu, additional, Ntsekhe, Mpiko, additional, Pandie, Shaheen, additional, Viljoen, Charle A., additional, De Andrade, Marianne, additional, Moccetti, Tiziano, additional, Rossi, M. Grazia, additional, Abdelhamid, Magdy, additional, Adel, Ahmed, additional, Kamal, Ahmed, additional, Mahrous, Hossam, additional, El Kaffas, Sameh, additional, El Fishawy, Hussien, additional, Pop, Calin, additional, Claudia, Matei, additional, Popescu, Bogdan A., additional, Ginghina, Carmen, additional, Deleanu, Dan, additional, Iliescu, Vlad A., additional, Al‐Mallah, Mouaz H., additional, Aljzeeri, Ahmed, additional, Najm, Hani, additional, Alghamdi, Ali, additional, Ramos, Walter Enrique Mogrovejo, additional, Kuanprasert, Srun, additional, Prommintikul, Arintaya, additional, Nawarawong, Weerachai, additional, Woragidpoonpol, Surin, additional, Tepsuwan, Thitipong, additional, Taksaudom, Noppon, additional, Rimsukcharoenchai, Chataroon, additional, Euathrongchit, Juntima, additional, Wannasopha, Yutthaphan, additional, Yamwong, Sukit, additional, Sritara, Piyamitr, additional, Aramcharoen, Suthara, additional, Meemuk, Krissada, additional, Khairuddin, Ahmad, additional, Hadi, Hafidz Abd, additional, and Yahaya, Shaiful Azmi, additional

Published
2024
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11. TCT-426 Optimal Use of the Recross Dual Lumen Microcatheter: A UK Registry

Author

Hung, John, primary, Ladwiniec, Andrew, additional, Mozid, Abdul, additional, Lucking, Andrew, additional, Smith, Elliot, additional, Gallagher, Sean, additional, Strange, Julian, additional, Elghamaz, Ahmed, additional, Bagnall, Alan, additional, Wilson, Simon, additional, Hill, Jonathan, additional, Palmer, Nick, additional, Henriksen, Peter, additional, O'Kane, Peter, additional, McEntegart, Margaret, additional, Walsh, Simon J., additional, and Spratt, James, additional

Published
2023
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12. Endothelial injury in atherosclerosis : identification of mediators and attenuation of inflammation by adenoviral augmentation of elafin and SLPI

Author

Henriksen, Peter Andrew

Subjects
616.1
Abstract

Gene expression profiling failed to identify candidate ‘endothelial protective’ mediators and attention focussed on elafin and secretory leucocyte protease inhibitor (SLPI), two low molecular weight elastase inhibitors. Elafin has been demonstrated within human coronary arteries although its function as a locally active antiprotease, antagonising the inflammatory effects of human neurophil elastase (HNE) and bacterial injury has best been characterised within the lung. Here we have used adenovirus as a vector to deliver elafin and SLPI genes to human endothelial cells and macrophages. We have devised a protocol involving pre-complexing of adenovirus with lipofectamine to enhance gene delivery and subsequent gene expression in human endothelial cells and to facilitate gene delivery to human macrophages. Elafin and SLPI overexpression were associated with reduced inflammatory cytokine production in endothelial cells and macrophages in response to a range of atherogenic stimuli including oxidised LDL. This anti-inflammatory activity was associated with reduced activation of the transcription factor NF-κB and preservation of its inhibitory sub-unit IκBα. Furthermore, elafin overexpression protected endothelial cells from HNE mediated injury and attenuated HNE mediated impairment of macrophage apoptotic cell recognition. In summary, angiopoietin-2 was identified as a novel mediator produced by endothelial cells in response to oxidised LDL and may contribute to plaque development through facilitation of neointimal angiogenesis. Adenoviral overexpression of elafin and SLPI exhibited therapeutic potential through reducing inflammatory responses and protecting the structure and function of endothelial cells and macrophages in the presence of atherogenic stimuli.

Published
2005

13. Abstract 13030: Causes of Cardiovascular and Non-cardiovascular Mortality in the Ischemia Trial

Author

Sidhu, Mandeep S, Alexander, Karen P, Huang, Zhen, O’Brien, Sean M, Chaitman, Bernard R, Stone, Gregg W, Newman, Jonathan D, Boden, William E, Maggioni, Aldo P, Steg, Philippe Gabriel, Ferguson, T Bruce, Demkow, Marcin, Peteiro, Jesus, Wander, Gurpreet S, de Belder, Mark A, Szwed, Hanna, Doerr, Rolf, Alexanderson, Erick, Polanczyk, Carisi, Henriksen, Peter, Conway, Dwayne, Miro, Vicente, Sharir, Tali, Rosenberg, Yves D, Bangalore, Sripal, Reynolds, Harmony R, Hochman, Judith S, and Maron, David J

Published
2020
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17. Nye undersøgelser af Bromme locus classicus

Author

Sørensen, Mikkel, Pedersen, Kristoffer Buck, Mortensen, Morten Fischer, Henriksen, Peter Steen, Hartmann, Niels, Sørensen, Lasse, Sørensen, Mikkel, Pedersen, Kristoffer Buck, Mortensen, Morten Fischer, Henriksen, Peter Steen, Hartmann, Niels, and Sørensen, Lasse

Published
2023

18. The concepts of a legal sanction and sanction regime : a EU blueprint for international criminal and financial law and a constitutional challenge for the EU financial sectors

Author

SAND-HENRIKSEN, Peter

Subjects
Sanctions (Law) -- European Union countries
Abstract

Defence date: 3 April 2023 Examining Board: Professor Stefan Grundmann, Humboldt University Berlin Professor Christos V. Gortsos, National and Kapodistrian University of Athens Professor Hans-W. Micklitz, European University Institute Professor André Klip, Maastricht University This Thesis aims to define the concept of a legal ‘sanction’ and develop the sanction theory and principles that are connected with this definition. Part I of this Thesis therefore establishes the theoretical, constitutional and international architecture for sanctions, whereby the philosophical and traditional views on punishment from the old theoretical discussions of the justification for punishment is providing the broader context for the legal concept of sanctions; the case-law of European Court of Human Rights on Articles 6 and 7 and Article 4 of Protocol 7 to the European Convention of Human Rights (ECHR) is providing the main foundation for establishing the constitutional concept of sanctions by providing the architecture and principles for constructing a legal concept of sanctions; and the international standards and principles on sanctioning which the EU Member States has agreed to comply with under the Financial Sector Assessment Program, a task jointly charged on the International Monetary Fund and World Bank, is providing the international aspects on financial sanctions. The conclusions made in Part I will be applied in Part II of this Thesis, which will discuss the EU regimes of sanctions in the financial sector by first establishing the concept of ‘sanction regimes’ and determine its structures and principles. Second, the general requirements for the imposition of sanctions will then be established and discussed just as the constitutional framework will be applied in order to assess the classification of the EU financial law. Third, the specific types of EU financial sanctions will then be analysed and discussed by the application of the Engel-test and the principles establishing the constitutional concept of sanctions. Finally, the last Chapter will bring it all together and answer the research questions examined in this Thesis.

Published
2023

20. Multiomics signatures of type 1 diabetes with and without albuminuria

Author

Clos-Garcia, Marc, primary, Ahluwalia, Tarunveer S., additional, Winther, Signe A., additional, Henriksen, Peter, additional, Ali, Mina, additional, Fan, Yong, additional, Stankevic, Evelina, additional, Lyu, Liwei, additional, Vogt, Josef K., additional, Hansen, Torben, additional, Legido-Quigley, Cristina, additional, Rossing, Peter, additional, and Pedersen, Oluf, additional

Published
2022
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21. Inside and out: recent studies of ancient meals in Denmark

Author

Henriksen, Peter Steen, Mortensen, Morten Fischer, and Hald, Mette Marie

Abstract

Two recent research projects focus on the remains of meals from, respectively, a collection of ancient latrines, and the Tollund Man bogbody. For both projects, the close collaboration between archaeobotanists and palynologists provide us with data that would not havebeen available with only one of the disciplines at hand. Where the larger plant remains represent the consumption of the seeds ofplants, pollen provides us with evidence of the flowering plants that were consumed before seeding. Together, we have been able todramatically increase the range of plant species identifed.

Published
2022

22. Prehistoric Plant Exploitation and Domestication: An Inspiration for the Science of De Novo Domestication in Present Times.

Author

Hebelstrup, Kim Henrik, Azariadis, Aristotelis, Cordes, Adam, Henriksen, Peter Steen, and Brinch-Pedersen, Henrik

Subjects
DOMESTICATION of plants, PLANT genetics, PLANT identification, BOTANISTS, PLANT species, SPECIES diversity
Abstract

De novo domestication is a novel trend in plant genetics, where traits of wild or semi-wild species are changed by the use of modern precision breeding techniques so that they conform to modern cultivation. Out of more than 300,000 wild plant species, only a few were fully domesticated by humans in prehistory. Moreover, out of these few domesticated species, less than 10 species dominate world agricultural production by more than 80% today. Much of this limited diversity of crop exploitation by modern humans was defined early in prehistory at the emergence of sedentary agro-pastoral cultures that limited the number of crops evolving a favorable domestication syndrome. However, modern plant genetics have revealed the roadmaps of genetic changes that led to these domestication traits. Based on such observations, plant scientists are now taking steps towards using modern breeding technologies to explore the potential of de novo domestication of plant species that were neglected in the past. We suggest here that in this process of de novo domestication, the study of Late Paleolithic/Late Archaic and Early Neolithic/Early Formative exploration of wild plants and identification of neglected species can help identify the barriers towards domestication. Modern breeding technologies may then assist us to break these barriers in order to perform de novo domestication to increase the crop species diversity of modern agriculture. [ABSTRACT FROM AUTHOR]

Published
2023
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24. Rationale and Design of the Cardiac CARE Trial: A Randomized Trial of Troponin-Guided Neurohormonal Blockade for the Prevention of Anthracycline Cardiotoxicity

Author

Henriksen, Peter A., primary, Hall, Peter, additional, Oikonomidou, Olga, additional, MacPherson, Iain R., additional, Maclean, Morag, additional, Lewis, Steff, additional, McVicars, Heather, additional, Broom, Angus, additional, Scott, Fiona, additional, McKay, Pam, additional, Borley, Annabel, additional, Rowntree, Clare, additional, Lord, Simon, additional, Collins, Graham, additional, Radford, John, additional, Guppy, Amy, additional, Payne, John R., additional, Newby, David E., additional, Mills, Nick L., additional, and Lang, Ninian N., additional

Published
2022
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25. Multiomics signatures of type 1 diabetes with and without albuminuria

Author

Clos-Garcia, Marc, Ahluwalia, Tarunveer S., Winther, Signe A., Henriksen, Peter, Ali, Mina, Fan, Yong, Stankevic, Evelina, Lyu, Liwei, Vogt, Josef K., Hansen, Torben, Legido-Quigley, Cristina, Rossing, Peter, Pedersen, Oluf, Clos-Garcia, Marc, Ahluwalia, Tarunveer S., Winther, Signe A., Henriksen, Peter, Ali, Mina, Fan, Yong, Stankevic, Evelina, Lyu, Liwei, Vogt, Josef K., Hansen, Torben, Legido-Quigley, Cristina, Rossing, Peter, and Pedersen, Oluf

Abstract

Aims/hypothesis: To identify novel pathophysiological signatures of longstanding type 1 diabetes (T1D) with and without albuminuria we investigated the gut microbiome and blood metabolome in individuals with T1D and healthy controls (HC). We also mapped the functional underpinnings of the microbiome in relation to its metabolic role. Methods: One hundred and sixty-one individuals with T1D and 50 HC were recruited at the Steno Diabetes Center Copenhagen, Denmark. T1D cases were stratified based on levels of albuminuria into normoalbuminuria, moderate and severely increased albuminuria. Shotgun sequencing of bacterial and viral microbiome in stool samples and circulating metabolites and lipids profiling using mass spectroscopy in plasma of all participants were performed. Functional mapping of microbiome into Gut Metabolic Modules (GMMs) was done using EggNog and KEGG databases. Multiomics integration was performed using MOFA tool. Results: Measures of the gut bacterial beta diversity differed significantly between T1D and HC, either with moderately or severely increased albuminuria. Taxonomic analyses of the bacterial microbiota identified 51 species that differed in absolute abundance between T1D and HC (17 higher, 34 lower). Stratified on levels of albuminuria, 10 species were differentially abundant for the moderately increased albuminuria group, 63 for the severely increased albuminuria group while 25 were common and differentially abundant both for moderately and severely increased albuminuria groups, when compared to HC. Functional characterization of the bacteriome identified 23 differentially enriched GMMs between T1D and HC, mostly involved in sugar and amino acid metabolism. No differences in relation to albuminuria stratification was observed. Twenty-five phages were differentially abundant between T1D and HC groups. Six of these varied with albuminuria status. Plasma metabolomics indicated differences in the steroido, Aims/hypothesis: To identify novel pathophysiological signatures of longstanding type 1 diabetes (T1D) with and without albuminuria we investigated the gut microbiome and blood metabolome in individuals with T1D and healthy controls (HC). We also mapped the functional underpinnings of the microbiome in relation to its metabolic role. Methods: One hundred and sixty-one individuals with T1D and 50 HC were recruited at the Steno Diabetes Center Copenhagen, Denmark. T1D cases were stratified based on levels of albuminuria into normoalbuminuria, moderate and severely increased albuminuria. Shotgun sequencing of bacterial and viral microbiome in stool samples and circulating metabolites and lipids profiling using mass spectroscopy in plasma of all participants were performed. Functional mapping of microbiome into Gut Metabolic Modules (GMMs) was done using EggNog and KEGG databases. Multiomics integration was performed using MOFA tool. Results: Measures of the gut bacterial beta diversity differed significantly between T1D and HC, either with moderately or severely increased albuminuria. Taxonomic analyses of the bacterial microbiota identified 51 species that differed in absolute abundance between T1D and HC (17 higher, 34 lower). Stratified on levels of albuminuria, 10 species were differentially abundant for the moderately increased albuminuria group, 63 for the severely increased albuminuria group while 25 were common and differentially abundant both for moderately and severely increased albuminuria groups, when compared to HC. Functional characterization of the bacteriome identified 23 differentially enriched GMMs between T1D and HC, mostly involved in sugar and amino acid metabolism. No differences in relation to albuminuria stratification was observed. Twenty-five phages were differentially abundant between T1D and HC groups. Six of these varied with albuminuria status. Plasma metabolomics indicated differences in the steroidogenesis and sugar metabolism and cir

Published
2022

35. Commissioning and qualification of the Low-Energy X-ray Reectometer and its utilization in development of X-ray mirror coatings for astronomical instrumentation

Author

Henriksen, Peter Lindquist

Abstract

With the continuous effort to study X-ray emission from astronomical objects, there is an ever increasing demand for observatories of high quality in terms of focusing properties of the energetic radiation and large photon collecting areas. The European Space Agency's next generation X-ray telescope, the Advanced Telescope for High Energy Astrophysics (Athena), is under development, and extensive studies are carried out to ensure that its scientific requirements will be met.The main purpose of this project was the commissioning, qualification, and utilization of a state-of-the-art compact Low-Energy X-ray Reflectometer with the aim of enabling quick characterization of mirrors at 1.487 keV, in order to evaluate the performance of low-density overcoatings and the impact of the Athena mirror post-coating processing and assembly steps on the quality of the coatings. The instrument was successfully commissioned and validated, and data acquisition modes were developed to optimize its performance and quality of measurements. The operational reflectometer has excellent measurement repeatability, high angular resolution, good spectral purity, and large dynamic range.With the use of the Low-Energy X-ray Reflectometer as well as 8.048 keV measurements and synchrotron measurements in the range 3.4-10 keV, characterization of carbon coatings were performed which indicated resistance of this material to the Athena mirror cleaning procedure, thus allowing carbon to be introduced as an Athena coating material candidate. Optimized iridium/carbon bilayers are shown to be stable over time, resistant to the cleaning procedure, and not adversely affected by post-coating annealing of the mirrors. Diamond-like carbon coatings were also studied but were not found to be significantly better than the regular sputtered carbon.The last part of this project concerned the optics development for a future axion helioscope called BabyIAXO. Simulations and numerical optimizations were carried out to determine the optimal geometry in terms of focal length and distribution of mirrors in its optic, as well as optimization of coating recipes. A focal length of just over 5 m and coatings consisting of simple bilayers, similar to those for Athena, were found to be best for the source in question. Test mirrors were produced, validating the compatibility of a baseline iridium coating with the cold-slumped glass approach envisioned for BabyIAXO.

Published
2021

36. Iridium thin-film coatings for the BabyIAXO hybrid X-ray optic

Author

Henriksen, Peter L., primary, Ferreira, Desiree D. M., additional, Massahi, Sonny, additional, Civitani, Marta C., additional, Basso, Stefano, additional, Vogel, Julia, additional, Armendariz, Jaime R., additional, Knudsen, Erik B., additional, Irastorza, Igor G., additional, and Christensen, Finn E., additional

Published
2021
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37. Borgring. Uncovering the strategy for a Viking Age ring fortress in Denmark

Author

Christensen, Jonas, primary, Daly, Aoife, additional, Henriksen, Peter Steen, additional, Holm, Nanna, additional, Jessen, Catherine, additional, Jørgensen, Sofie, additional, Olesen, Line, additional, Olesen, Jesper, additional, Schultz, Maja Kildetoft, additional, Sindbæk, Søren Michael, additional, and Ulriksen, Jens, additional

Published
2021
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38. The lost landscape of Borgring

Author

Jessen, Catherine, primary, Henriksen, Peter Steen, additional, Hald, Mette Marie, additional, Sindbæk, Søren Michael, additional, and Ulriksen, Jens, additional

Published
2021
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41. Role of serum biomarkers in cancer patients receiving cardiotoxic cancer therapies

Author

Pudil, Radek, Mueller, Christian, Celutkiene, Jelena, Henriksen, Peter A., Lenihan, Dan, Dent, Susan, Barac, Ana, Stanway, Susanna, Moslehi, Javid, Suter, Thomas M., Ky, Bonnie, Sterba, Martin, Cardinale, Daniela, Cohen-Solal, Alain, Tocchetti, Carlo Gabriele, Farmakis, Dimitrios, Bergler-Klein, Jutta, Anker, Markus S., Von Haehling, Stephan, Belenkov, Yury, Iakobishvili, Zaza, Maack, Christoph, Ciardiello, Fortunato, Ruschitzka, Frank, Coats, Andrew J. S., Seferovic, Petar, Lainscak, Mitja, Piepoli, Massimo F., Chioncel, Ovidiu, Bax, Jereon, Hulot, Jean-Sebastien, Skouri, Hadi, Hagler-Laube, Eva Simona, Asteggiano, Riccardo, Fernandez, Teresa Lopez, de Boer, Rudolf A., Lyon, Alexander R., and Cardiovascular Centre (CVC)

Subjects
CARDIOVASCULAR TOXICITY, MULTIPLE BIOMARKERS, Radiotherapy, Heart failure, TRASTUZUMAB-INDUCED CARDIOTOXICITY, Proteasome inhibitors, ACUTE CORONARY SYNDROME, PLUS TRASTUZUMAB, Vascular endothelial growth factor inhibitors, Cardiotoxicity, Cardio-oncology, Myocarditis, Immune checkpoint inhibitors, B-type natriuretic peptides, MYOCARDIAL-INFARCTION, BRAIN NATRIURETIC PEPTIDE, SENSITIVITY CARDIAC TROPONIN, HEART-FAILURE, BREAST-CANCER, Cardiac troponin, Anthracyclines, HER2-targeted therapies, Biomarkers
Abstract

Serum biomarkers are an important tool in the baseline risk assessment and diagnosis of cardiovascular disease in cancer patients receiving cardiotoxic cancer treatments. Increases in cardiac biomarkers including cardiac troponin and natriuretic peptides can be used to guide initiation of cardioprotective treatments for cancer patients during treatment and to monitor the response to cardioprotective treatments, and they also offer prognostic value. This position statement examines the role of cardiac biomarkers in the management of cancer patients. The Cardio-Oncology Study Group of the Heart Failure Association (HFA) of the European Society of Cardiology (ESC) in collaboration with the Cardio-Oncology Council of the ESC have evaluated the current evidence for the role of cardiovascular biomarkers in cancer patients before, during and after cardiotoxic cancer therapies. The characteristics of the main two biomarkers troponin and natriuretic peptides are discussed, the link to the mechanisms of cardiovascular toxicity, and the evidence for their clinical use in surveillance during and after anthracycline chemotherapy, trastuzumab and HER2-targeted therapies, vascular endothelial growth factor inhibitors, proteasome inhibitors, immune checkpoint inhibitors, cyclophosphamide and radiotherapy. Novel surveillance clinical pathways integrating cardiac biomarkers for cancer patients receiving anthracycline chemotherapy or trastuzumab biomarkers are presented and future direction in cardio-oncology biomarker research is discussed.

Published
2020

42. Full-scale bioremediation of diesel-polluted soil in an Arctic landfarm

Author

Johnsen, Anders R, Boe, Uffe S, Henriksen, Peter, Malmquist, Linus M.V., Christensen, Jan H., Johnsen, Anders R, Boe, Uffe S, Henriksen, Peter, Malmquist, Linus M.V., and Christensen, Jan H.

Abstract

A full-scale, experimental landfarm was tested for the capacity to biodegrade oil-polluted soil under high-Arctic tundra conditions in northeast Greenland at the military outpost 9117 Station Mestersvig. Soil contaminated with Arctic diesel was transferred to the landfarm in August 2012 followed by yearly addition of fertilizer and plowing and irrigation to optimize microbial diesel biodegradation. Biodegradation was determined from changes in total petroleum hydrocarbons (TPH), enumeration of specific subpopulations of oil-degrading microorganisms (MPN), and changes in selected classes of alkylated isomers and isomer ratios. Sixty-four percent of the diesel was removed in the landfarm within the first year, but a recalcitrant fraction (18%) remained after five years. n-alkanes and naphthalenes were biodegraded as demonstrated by changing isomer ratios. Dibenzothiophenes and phenanthrenes showed almost constant isomer ratios indicating that their removal was mostly abiotic. Oil-degrading microorganisms were present for the major components of diesel (n-alkanes, alkylbenzenes and alkylnaphthalenes). The degraders showed very large population increases in the landfarm with a peak population of 1.2 × 109 cells g-1 of total diesel degraders. Some diesel compounds such as cycloalkanes, hydroxy-PAHs and sulfur-heterocycles had very few or no specific degraders, these compounds may consequently be degraded only by slow co-metabolic processes or not at all.

Published
2021

43. Identification of prehistoric malting and partial grain germination from starch granules in charred barley grains

Author

Cordes, Adam, Henriksen, Peter Steen, Hald, Mette Marie, Sørensen, Lasse, Nielsen, Poul Otto, Xu, Jinchuan, Lund, Jørgen, Møller, Niels Algreen, Nielsen, Finn Ole Sonne, Sarauw, Torben, Simonsen, John, Sparrevohn, Lotte Reedtz, Westphal, Jørgen, Blennow, Andreas, Hebelstrup, Kim Henrik, Cordes, Adam, Henriksen, Peter Steen, Hald, Mette Marie, Sørensen, Lasse, Nielsen, Poul Otto, Xu, Jinchuan, Lund, Jørgen, Møller, Niels Algreen, Nielsen, Finn Ole Sonne, Sarauw, Torben, Simonsen, John, Sparrevohn, Lotte Reedtz, Westphal, Jørgen, Blennow, Andreas, and Hebelstrup, Kim Henrik

Abstract

This paper presents results from a study of starch granules in charred archaeological grains with the purpose of identifying markers of malting. Starch granules are microstructures from plant organs that can be identified to the level of plant genus based on their shape and size. Starch granules have been extracted from archaeological deposits. However, surprisingly few studies have focused on identifying starch granules preserved in the actual cereal grains. This study included experimental charring of modern cereal grains to investigate whether starch granules survive charring, as well as investigating an assemblage of charred barley grains from Danish archaeological excavations spanning the Early Neolithic (3900 BCE) to the Late Viking Age (1050 CE). We show that starch granule structures can be preserved in charred archaeological grains using Scanning Electron Microscopy (SEM). Three different types/phases of starch granule preservation in charred archaeological grains are observed: 1) separate granules, 2) partly plastisized granules and 3) fully plastisized granules. Two grains dated to the Viking Age (800 CE – 1050 CE) and 1st century CE (Roman Iron Age), respectively, had holes on the surface of their starch granule similar to those seen in malted/germinated barley (called amylolytic pores). Both grains were found in circumstances with other indications of malting activity. Another grain dated to 50 BCE (Pre-Roman Iron Age) also contained starch granules with amylolytic pores that marks the beginning of germination. However, this grain was found in a vessel of stored unthreshed grain in a grain storage basement and therefore is more likely to be an outcome of unintended germination. The identification of the germination process – accidental or deliberate – from starch granules in charred cereal grains means that we are now able to identify malting in prehistory from the cereal grains themselves, including naked grains, which has hitherto not been possible

Published
2021

44. Development of low-density coatings for soft x-ray reflectivity enhancement for ATHENA and other missions

Author

O'Dell, Stephen L., Gaskin, Jessica A., Pareschi, Giovanni, Cotroneo, Vincenzo, Bruni, Ricardo, Döhring, Thorsten, Ferreira, Desiree, Gibertini, Eugenio, Henriksen, Peter, Magagnin, Luca, Massahi, Sonny, Romaine, Suzanne, Sethares, Leandra, Sironi, Giorgia, Spiga, Daniele, Tagliaferri, Gianpiero, Valsecchi, Giuseppe, O'Dell, Stephen L., Gaskin, Jessica A., Pareschi, Giovanni, Cotroneo, Vincenzo, Bruni, Ricardo, Döhring, Thorsten, Ferreira, Desiree, Gibertini, Eugenio, Henriksen, Peter, Magagnin, Luca, Massahi, Sonny, Romaine, Suzanne, Sethares, Leandra, Sironi, Giorgia, Spiga, Daniele, Tagliaferri, Gianpiero, and Valsecchi, Giuseppe

Abstract

Metallic coatings made of precious metals (e.g. Ir, Pt or Au) with high atomic number Z have been traditionally employed at grazing incidence for X-rays reflection and focalization. These materials offer a range of reflection extended to higher energies, but also present a series of absorption edges, which limit the reflectivity in the 2-4 keV band and below. Therefore the search for alternative coatings, able to improve the reflection in the soft energy range, is particularly relevant for the development of future telescopes, like ATHENA (ESA), Lynx (NASA) and eXTP (CAS). Low-Z overcoatings (e.g. carbon or B4C), applied on top of the high-Z metallic layer, can enhance the reflectivity in the softer band (mainly below 2 keV), but conventional deposition methods for these materials are not easily compatible with some of the mainstream technologies for mirror fabrication (notably, the silicon pore optics that will be used for the ATHENA X-ray mission which is being implemented by ESA). In this work we discuss novel solutions (carbon-like overcoatings realized by dip coating or vapor phase deposition), which can be particularly convenient for the application to ATHENA and to future telescopes.

Published
2021

45. Effect of mirror curvature on the angular resolution of silicon pore optics

Author

O'Dell, Stephen L., Gaskin, Jessica A., Pareschi, Giovanni, Jegers, Arne S., Ferreira, Desiree Della Monica, Bergbäck Knudsen, Erik, Massahi, Sonny, Svendsen, Sara, Lindquist Henriksen, Peter, Gellert, Nis Christian, Sironi, Giorgia, Spiga, Daniele, Ferreira, Ivo, Shortt, Brian, Bavdaz, Marcos, O'Dell, Stephen L., Gaskin, Jessica A., Pareschi, Giovanni, Jegers, Arne S., Ferreira, Desiree Della Monica, Bergbäck Knudsen, Erik, Massahi, Sonny, Svendsen, Sara, Lindquist Henriksen, Peter, Gellert, Nis Christian, Sironi, Giorgia, Spiga, Daniele, Ferreira, Ivo, Shortt, Brian, and Bavdaz, Marcos

Abstract

Silicon Pore Optics are a novel technology for focusing high-energy photons, where pairs of mirror plates stacked into mirror modules. This paper presents a study of the angular resolution of SPO mirror assemblies, using a selection of sagittal mirror curvatures. Results were achieved by ray-tracing the different configurations of the mirror with the ray tracing software SPORT, or Silicon Pore Optics Ray Tracer, using an observation of the Crab Nebula originally obtained by Chandra. It is found that a true Wolter geometry most closely reproduces the original image, while geometries with a conic approximation on either their primary or secondary mirrors create the most diffuse image. A geometry with conic approximations on both primary and secondary mirrors falls in between the two extremes.

Published
2021

46. Detection of anatoxin-a(s) in environmental samples of cyanobacteria by using a biosensor with engineered acetylcholinesterases

Author

Devic, Eric, Dunhai Li, Dauta, Alain, Henriksen, Peter, Codd, Geoffrey A., Marty, Jean-Louis, and Fournier, Didier

Subjects
Microbiological research -- Analysis, Microbiology -- Environmental aspects, Cyanobacteria -- Physiological aspects, Acetylcholinesterase -- Physiological aspects, Biosensors -- Physiological aspects, Microbial toxins -- Environmental aspects, Enzymes -- Genetic aspects, Gene mutations -- Physiological aspects, Biological sciences
Abstract

Research has been conducted on the anatoxin-a(s) detection. The study of the sensitive to anatoxin-a(s) acetylcholinesterase carried out in obtaining high sensitivity and of the mutant enzymes which identify cyanobacterial toxins is presented.

Published
2002

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