1. Is a Wider Margin (2 cm vs. 1 cm) for a 1.01–2.0 mm Melanoma Necessary?
- Author
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Doepker, Matthew P, Thompson, Zachary J, Fisher, Kate J, Yamamoto, Maki, Nethers, Kevin W, Harb, Jennifer N, Applebaum, Matthew A, Gonzalez, Ricardo J, Sarnaik, Amod A, Messina, Jane L, Sondak, Vernon K, and Zager, Jonathan S
- Subjects
Biomedical and Clinical Sciences ,Clinical Sciences ,Oncology and Carcinogenesis ,Clinical Research ,Dental/Oral and Craniofacial Disease ,Cancer ,Rare Diseases ,Adolescent ,Adult ,Aged ,Aged ,80 and over ,Female ,Follow-Up Studies ,Humans ,Lymph Node Excision ,Male ,Melanoma ,Middle Aged ,Neoplasm Recurrence ,Local ,Prognosis ,Retrospective Studies ,Sentinel Lymph Node Biopsy ,Skin Neoplasms ,Survival Rate ,Young Adult ,Oncology & Carcinogenesis ,Oncology and carcinogenesis - Abstract
BackgroundThe current NCCN recommendation for resection margins in patients with melanomas between 1.01 and 2 mm deep is a 1-2 cm radial margin. We sought to determine whether margin width had an impact on local recurrence (LR), disease-specific survival (DSS), and type of wound closure.MethodsMelanomas measuring 1.01-2.0 mm were evaluated at a single institution between 2008 and 2013. All patients had a 1 or 2 cm margin.ResultsWe identified 965 patients who had a 1 cm (n = 302, 31.3 %) or 2 cm margin (n = 663, 68.7 %). Median age was 64 years, and 592 (61.3 %) were male; 32.5 and 48.7 % of head and neck and extremity patients had a 1 cm margin versus 18.9 % of trunk patients (p
- Published
- 2016