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The south‐east margin of the Xing'an–Mongolian Orogenic Belt (SM‐XMOB) is a tectonic junction that is characterized by widespread Late Palaeozoic to Early Mesozoic igneous rocks. To determine the tectonic settings and provide new constraints on the regional tectonic evolution, petrological, geochronological, geochemical, and Hf isotope analyses have been conducted on the Permian volcanic rocks along the SM‐XMOB. Zircon U–Pb geochronological data indicate that these rocks were formed at 271.4 ± 3.2 Ma and 268.3 ± 3.2 Ma during the Early–Middle Permian. Geochemical results suggest that the volcanic rock samples have 61.5–66.4 wt% SiO2 and 0.98–1.71 wt% MgO, and belong to the calc‐alkaline series, suggesting an affinity with fractionated I‐type granite. They also exhibit positive zircon εHf (t) values ranging from + 8.6 to + 14.7, indicating that the primary magmas were dominantly derived from partial melting of Early Palaeozoic juvenile lower crustal. These volcanic rocks show an enrichment in large‐ion lithophile elements (LILEs; e.g., Rb, Th, and U) and depletion in high‐field‐strength elements (HFSEs; e.g., Nb, Ta, Ti, and P), similar to that from an active continental margin setting. We therefore propose that the widespread Permian volcanic rocks in the SM‐XMOB were closely associated with the southward subduction of the Palaeo‐Asian Ocean (PAO) Plate to the lithosphere beneath the XMOB, and that the PAO had not closed prior to the Middle Permian in the SM‐XMOB. [ABSTRACT FROM AUTHOR]

The Yangbishan iron–tungsten deposit, located in the central part of the Jiamusi Massif, Heilongjiang Province, NE China, is the oldest tungsten deposit in NE China to date. Both ore‐forming conditions and mineralisation characteristics indicate that tungsten mineralisation belongs to the skarn type. Petrography, microthermometric measurements and laser Raman spectroscopy of fluid inclusions in quartz grains associated with scheelite indicate that the ore‐forming fluid of the tungsten mineralisation in Yangbishan deposit belonged to the moderate‐temperature NaCl–H2O–CH4±N2 system. Fluid inclusion analyses indicate that ore‐forming fluid experienced decreasing temperatures and fluid degassing, inducing scheelite precipitation. Analysis of C, H and O isotopes of fluid inclusions within scheelite grains show δ13C values varying from −20.7 to −24.9‰, δD from −109.9 to −119.9‰, δ18O from 6.8 to 10.0‰ and δ18OH2O from 8.7 to 11.9‰. These data, together with C, H and O isotope compositions of the quartz associated with scheelite in tungsten ores, imply that ore‐forming fluid was derived dominantly from magma but influenced by organic material (reducing carbon) derived from wall rocks. Sm/Nd ratios of scheelite vary from 0.15 to 0.21, εNd (t = 520 Ma) values from −5.64 to −17.95 (average of −10.21) and TDM2 values from 702 and 2693 Ma (average of 2070 Ma), indicating the ores were sourced from ancient crustal rocks. The compositions of C–H–O–S–Pb and Nd isotopes support the fact that interaction between crust‐derived magma and strata rich in organics played an important role in the tungsten mineralisation of the Yangbishan deposit. [ABSTRACT FROM AUTHOR]

Ultrahigh‐temperature (UHT) mafic granulites in the southern part of the Shiguai area in Daqingshan, China, crop out within the Shanheyuan Gneiss of the Khondalite Belt (KB), a Paleoproterozoic tectonic belt in the Western Block of the North China Craton (NCC). The UHT mafic granulites occur within hypersthene‐bearing dioritic–granitic gneiss as irregular lenses and deformed dike swarms. Four metamorphic generation assemblages (M1–M4) are recognized in the studied samples. M1 is defined by the enclosed orthopyroxene and clinopyroxene within the "red eye" corona of the garnet, representing the prograde metamorphic stage. M2 (UHT granulite‐facies) is marked by the appearance of "red eye" corona of the garnet, with mineral assemblages of grt–cpx–opx–pl–ilm–q. M3 is defined by spinel‐rich symplectites between garnet and orthopyroxene, including grt–opx–pl–spl–mt–ilm. M4 (amphibolite facies) is featured by the development of amphibole. Phase equilibrium modelling and some critical thermobarometers are combined to constrain the P–T evolution of the studied samples. The P–T conditions for the M1–M4 are respectively estimated at ~8 kbar/~771–852°C, ~9.4–10.0 kbar/~930–965°C, ~5.0–5.4 kbar/~865–910°C, ~5.0–5.2 kbar/~675–682°C, which define a clockwise P–T path, involving near‐isothermal decompression following the peak metamorphism. The P–T path indicates that the rocks underwent a sequence of tectonothermal processes that started with crustal thickening (M1–M2), followed by rapid crustal uplift (M3) and cooling (M4). This process is inferred that the metamorphism of the UHT mafic granulites was associated with rapid exhumation and uplift that followed the continent–continent collision and amalgamation of the Yinshan and Ordos blocks. This amalgamation formed the Paleoproterozoic KB in the Western Block of the NCC. [ABSTRACT FROM AUTHOR]

The Shanmen Ag deposit, located in the southeastern part of the Siping area, Jilin Province, is one of the large-scale Ag deposits in Northeastern (NE) China. Almost all Ag orebodies, Ag-bearing quartz-sulfide veins are strictly controlled by NE-trending faults or brittle fractures and are hosted in the Yanshanian monzonite and quartz diorite. In terms of deposit geology, three mineralization stages are recognized: the pyrite-quartz stage (I), the quartz-Ag-polymetallic sulfide stage (II), and the carbonate-quartz stage (III). The research results of the fluid inclusions in the different stages indicate that the early stage (Stage I) mainly contains three types of fluid inclusions: liquid-rich two-phase (L-type), vapor-rich two-phase (V-type), and CO2 aqueous multi-phase (C-type). The fluid belongs to a medium–high temperature and medium–low salinity H2O-NaCl-CO2 system and has boiling characteristics. The middle stage (Stage II) is mainly characterized by liquid-rich two-phase (L-type) and vapor-rich two-phase (V-type) inclusions, in which the mixing of fluids of different nature leads to the escape of CO2. Only liquid-rich two-phase (L-type) inclusions are distinguished in the late stage (Stage III). The fluids of two later stages belong to the medium-low-temperature and low-salinity H2O-NaCl system. Homogenization temperatures from the early to late stages range from 272.2 to 412.5 °C, 124.1 to 313.3 °C, and 128.6 to 224 °C, respectively. Fluid salinities in the early to late stages range from 1.6 to 12.1, 1.4 to 8.9, and 0.4 to 5.8 wt.% NaCl equivalent, respectively. The gradually decreasing trends of homogenization temperatures and salinities and the reduction in the CO2 content indicate that the release of CO2 and the low-temperature environment are important causes of the precipitation of Ag-bearing minerals. The δ18OH2O values of the ore-bearing quartz veins in the different stages range from −3.7 to +8.1‰, and the δD values of fluid inclusions in the quartz range from −113 to −103‰, indicating that the initial ore-forming fluid was mainly derived from magma and that the input of meteoric water gradually increased during the mineralization process. The δ34S values (ranging from −11.4‰ to +1.8‰) and Pb isotope compositions (206Pb/204Pb = 18.143–18.189, 207Pb/204Pb = 15.543–15.599, 208Pb/204Pb = 38.062–38.251) of sulfides suggest that the ore-forming materials have mixed mantle and crustal sources. Therefore, we propose that the release of CO2 and the low-temperature environment are important conditions for silver minerals precipitation, and the mixing of fluids of different nature is the dominant mechanism causing precipitation. The Shanmen Ag deposit can be classified as an intrusion-related medium–low temperature hydrothermal vein-type deposit. [ABSTRACT FROM AUTHOR]

Sepsis is a syndrome of organ dysfunction caused by a dysregulated immune response to infection, with high morbidity and mortality. At present, there have been many advances in the study of its pathogenesis, especially the cardiac dysfunction caused by sepsis, namely sepsis-induced myocardial dysfunction, SIMD, which has received widespread attention. The mechanisms of SIMD mainly include excessive release of inflammatory mediators, impaired mitochondrial function, autophagy, apoptosis and myocardial dysfunction. This article reviews the pathogenesis of SIMD and elaborates on the progress in its treatment, aiming to improve the prognosis of patients with SIMD and sepsis., Competing Interests: The authors report no conflicts of interest in this work., (© 2024 Hao et al.)